Acetaldehyde supplier | CasNO.75-07-0

Name
Acetic aldehyde
EINECS 200-836-8
CAS No. 75-07-0
Article Data3149
CAS DataBase
Density 0.748 g/cm³
Solubility > 500 g/L (20 °C) in water
Melting Point -123 °C
Formula C₂H₄O
Boiling Point 18.588 °C at 760 mmHg
Molecular Weight 44.0532
Flash Point 133°F
Transport Information UN 1198 3/PG 3
Appearance clear, colorless liquid
Safety 36/37-33-16-26
Risk Codes 23/24/25-34-40-43-36/37-12-67-11-41-22-10
Molecular Structure
Hazard Symbols F+, Xn, F, T
Synonyms Aceticaldehyde;Ethanal;Ethyl aldehyde;NSC 7594;
PSA 17.07000
LogP 0.20520

Synthetic route

: 64-17-5
ethanol

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With CuO2H at 45℃; for 4h; under 30W sonication;	100%
With PQQTME; calcium perchlorate; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile Oxidation;	100%
With oxygen; iron(III) perchlorate; ozone Kinetics; Reagent/catalyst; Concentration;	100%

: 74-85-1
ethene

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With bis(benzonitrile)palladium(II) dichloride; py.Co(N,N'-bis(alicylidene-o-phenylene)diamino).NO2 In tetrahydrofuran at 50℃; under 760 Torr; for 0.916667h;	100%
With bis(benzonitrile)palladium(II) dichloride; py.Co(N,N'-bis(alicylidene-o-phenylene)diamino).NO2 In tetrahydrofuran at 50℃; under 760 Torr; for 0.916667h; Product distribution; influence of Pd/Co ratio, solvent, further olefins;	100%
With aluminum(III) sulfate; water at 350 - 360℃;

: 108-05-4
vinyl acetate

: 100-51-6
benzyl alcohol

A: 140-11-4
Benzyl acetate

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With 1,3-dicyclohexylimidazolium-2-thiocarboxylate In tetrahydrofuran at 80℃; for 2h; Inert atmosphere;	A 100% B n/a
With lipase from Pseudomonas Cepacia In benzene at 35℃; other ω-substituted-1-alkanols, var. solvents; kinetic parameters of transesterification;

...Expand

: 16457-30-0
hydridopentacarbonylrhenium(I)

: pentacarbonyl(methyl)manganese(I)

: 2206-26-0
[D3]acetonitrile

A: 98688-79-0
(CO)5ReMn(CO)4(C(2)H3CN)

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
In [D3]acetonitrile MeMn(CO)5, CD3CN, and HRe(CO)5 were vac. transferred into an NMR tube, the tube was sealed, thawed, and rapidly placed in the instrument probe (ca. 30°C), reaction was complete within 35 min; followed by (1)H NMR, MeCHO was identified by (1)H NMR, (CO)5ReMn(CO)4(CD3CN) was isolated by preparative layer chromy. on SiO2 followed by recrystn. from CH2Cl2/hexanes (ca. 1:3) at -25°C; elem. anal.;	A 62% B 100%

Yield

In [D3]acetonitrile MeMn(CO)5, CD3CN, and HRe(CO)5 were vac. transferred into an NMR tube, the tube was sealed, thawed, and rapidly placed in the instrument probe (ca. 30°C), reaction was complete within 35 min; followed by (1)H NMR, MeCHO was identified by (1)H NMR, (CO)5ReMn(CO)4(CD3CN) was isolated by preparative layer chromy. on SiO2 followed by recrystn. from CH2Cl2/hexanes (ca. 1:3) at -25°C; elem. anal.;

A 62%
B 100%

...Expand

: 22372-70-9, 18972-42-4
H2Os(CO)4

: pentacarbonyl(methyl)manganese(I)

A: 33292-90-9
Os(CO)4(Mn(CO)5)2

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
In [D3]acetonitrile MeMn(CO)5, H2Os(CO)4 (2:1 molar ratio), and CD3CN were sealed in a NMR tube under vac., the tube was thawed, reaction was complete in 70 min; monitored by (1)H NMR, yield of MeCHO was detd. by integration of the corresponding peak in the (1)H NMR spectrum, Mn2Os(CO)14 was identified by its IR and mass spectra;	A n/a B 100%
With carbon monoxide In tetrahydrofuran MeMn(CO)5 and H2Os(CO)4 (2:1 molar ratio) in THF were reacted overnightat room temp. (IR spectrum showed the presence of MeCHO), soln. was frozen, degassed, and CO (2 atm) admitted, reaction was stirred overnight at room temp.; product was isolated via preparative layer chromy.;	A 68% B n/a
With carbon monoxide In acetonitrile MeMn(CO)5, H2Os(CO)4 (2:1 molar ratio), and MeCN were reacted for 8 h at room temp., solvent was removed under vac., residue taken up in CH2Cl2, soln. was frozen, degassed, and CO (2 atm) admitted, reaction was stirred for 32 h in the dark at room temp.; product was isolated via preparative layer chromy.;	A 62% B n/a

...Expand

: 75-05-8
acetonitrile

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With potassium carbonate In water; dimethyl sulfoxide at 60℃; for 8h; High pressure; Green chemistry;	99.9%
With tin(ll) chloride
With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; triethylamine Quantum yield; Product distribution; Mechanism; Irradiation; further metal-complexes;

: 108-05-4
vinyl acetate

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

A: 21040-45-9
Cinnamyl acetate

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
[(nBuSn)12(μ3-O)14(μ2-OH)6](2+)*2(2,5-Me2C6H3SO3(1-)) at 75℃; for 4.5h;	A 99% B n/a

...Expand

: (H2O)5CrCH(CH3)OH(2+)

A: chromium (III) ion

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With Fe(3+) In ethanol; water Kinetics; byproducts: H(1+); excess of Fe(3+) in 1 M aq. EtOH at 24.8°C under N2 by controlled ionic strength;	A n/a B 99%
With Cu(2+) In ethanol; water Kinetics; byproducts: H(1+); excess of Cu(2+) in 1 M aq. EtOH at 24.8°C under N2 by controlled ionic strength;	A n/a B >99

: 542-10-9
ethylidene diacetate

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With ethanol at 50℃; for 0.166667h; chemoselective reaction;	98%
durch thermische Zersetzung;
durch thermische Zersetzung;

: NiMe2(PEt3)2

A: 16787-33-0
(CO)2Ni(P(C2H5)3)2

B: 75-07-0
acetaldehyde

C: 431-03-8
dimethylglyoxal

D: 67-64-1
acetone

Conditions

Conditions	Yield
With carbon monoxide In diethyl ether Et2O soln. of Ni complex stirred under CO at -78°C for 0.2 h, warmed to room temp.; drying up; GLC anal.;	A n/a B 0% C 0% D 98%

...Expand

: N-fluoro-N-(1-(m-tolyl)ethyl)benzenesulfonamide

A: 13587-57-0
N-m-tolyl-benzenesulfonamide

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃;	A 98% B n/a

: 109-53-5
isobutyl vinyl ether

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With sulfuric acid; water In neat (no solvent) at 80 - 100℃; for 3.5h; Temperature;	97%
Hydrolysis;

: 88099-81-4
2-methyl-23-crown-8

A: 5617-32-3
heptaethylene glycol

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With water; hydrogenchloride In 1,4-dioxane Rate constant; Equilibrium constant; Ambient temperature; effect of alkali and alkaline earth metal chlorides and concentrations of alkali-metal chlorides and HCl;	A n/a B 97%

: 108-05-4
vinyl acetate

: 98-85-1, 13323-81-4
1-Phenylethanol

A: 93-92-5, 50373-55-2
1-phenylethyl acetate

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
[(nBuSn)12(μ3-O)14(μ2-OH)6](2+)*2(2,5-Me2C6H3SO3(1-)) at 75℃; for 5.5h;	A 97% B n/a
In isopropyl ether at 23℃; Enzymatic reaction;

...Expand

: 4-chloro-N-fluoro-N-(1-phenylethyl)benzenesulfonamide

A: 7454-47-9
4-chloro-N-phenyl-benzenesulfonamide

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃;	A 97% B n/a

: 108-05-4
vinyl acetate

: 2612-30-8
2-benzyl-1,3-propanediol

A: 110270-49-0
(R)-3-acetoxy-2-benzyl-1-propanol

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
Lipase P at 25℃; for 1.5h;	A 96% B n/a

...Expand

: 88099-82-5
2-methyl-26-crown-9

A: 5117-19-1
octaethylene glycol

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With water; hydrogenchloride In 1,4-dioxane Rate constant; Equilibrium constant; Ambient temperature; effect of alkali-metal chlorides;	A n/a B 96%

: N-fluoro-N-(1-phenylethyl)benzenesulfonamide

A: 1678-25-7
N-phenylbenzenesulfonamide

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃; Reagent/catalyst;	A 96% B n/a

: N-(1-(3,4-dimethylphenyl)ethyl)-N-fluorobenzenesulfonamide

A: N-(3,4-dimethylphenyl)benzenesulfonamide

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃;	A 96% B n/a

: N-fluoro-N-(1-(naphthalen-2-yl)ethyl)benzenesulfonamide

A: 7504-85-0
N-(naphthalen-2-yl)benzenesulfonamide

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃;	A 96% B n/a

: 83206-73-9
percarbonate de O,O-α-cumyle et O-vinyle

A: 124-38-9
carbon dioxide

B: 617-94-7
1-methyl-1-phenylethyl alcohol

C: 698-91-9
2-phenoxypropene

D: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
In various solvent(s) Product distribution; other solvent;	A n/a B n/a C 95% D n/a

...Expand

: N-fluoro-4-nitro-N-(1-phenylethyl)benzenesulfonamide

A: 1576-44-9
N-nosylaniline

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃;	A 95% B n/a

: 87051-08-9
(4aS,10aR)-2,4a,9-Trimethyl-4a,10a-dihydro-1,3,4-trioxa-phenanthrene

: 114390-56-6
(1S,2R)-1,4-Dimethyl-1,2-dihydro-naphthalene-1,2-diol

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With acetic acid; zinc In diethyl ether at -5℃; for 1.5h;	A 94% B n/a

: 624-64-6
trans-2-Butene

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With oxygen; ozone In gas Product distribution; gas-phase ozonolysis of alkenes; formation of OH radicals; use of CO as scavenger for OH radicals;	94%
With ozone at 24.85℃; under 760 Torr; for 0.166667h; Oxidation;

: 75-00-3
chloroethane

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With oxygen; kieselguhr; copper(l) chloride In dichloromethane for 1.5h; Oxidation; Heating;	94%

: 27131-71-1
2-methyl-3-oxo-1,4-dioxaspiro<4.5>decane

A: 108-94-1
cyclohexanone

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
at 800℃; Product distribution; other temperatures;	A 93% B n/a

: 80857-63-2
β-isopropoxyethyl vinyl sulfoxide

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
at 280 - 290℃; for 1.5h; Product distribution;	93%

: 38982-12-6
3-(anthracene-9-yl)acrylaldehyde

A: 75-07-0
acetaldehyde

B: 642-31-9
9-anthracene aldehyde

Conditions

Conditions	Yield
With tetra(n-butyl)ammonium hydroxide; water at 150℃; for 0.166667h; Reagent/catalyst; Microwave irradiation; Green chemistry;	A n/a B 93%

: N-fluoro-N-(1-(p-tolyl)ethyl)benzenesulfonamide

A: 6311-65-5
N-p-tolyl-benzenesulfonamide

B: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With formic acid at 50℃;	A 93% B n/a

: 74-96-4
ethyl bromide

: 75-07-0
acetaldehyde

Conditions

Conditions	Yield
With C30H38Cl2Ir2N4 In dimethyl sulfoxide at 30℃; for 4.5h;	93%

: 534-22-5
2-methylfuran

: 75-07-0
acetaldehyde

: 3209-79-8
1,1-bis<2-(5-methyl)-furyl>-ethane

Conditions

Conditions	Yield
With ion-exchange resin Lewatit SPC 108 (acid form) In 1,4-dioxane; water at 20℃; for 1h;	100%
With N-(trifluoromethanesulfonyl)phosphoramidic acid diphenyl ester In toluene at 20 - 95℃; for 5h;	81%
With o-benzenedisulfonimide In toluene at 90℃; for 5h;	80%
With hydrogenchloride
With improved graphene oxide In neat (no solvent) at 60℃; for 6h;

: 109-80-8
1.3-propanedithiol

: 75-07-0
acetaldehyde

: 6007-26-7
2-methyl-1,3-dithian

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane at 0℃; for 1h;	100%
acid	74%
With toluene-4-sulfonic acid In benzene for 6h; Heating;	70%

: 14316-14-4
N-(2-hydroxy-ethyl)-4-methyl-benzenesulfonamide

: 75-07-0
acetaldehyde

: 2-methyl-3-tosyloxazolidine

Conditions

Conditions	Yield
With amberlyst-15 In dichloromethane at 20℃; for 2h; Inert atmosphere; Molecular sieve;	100%
With hydrogenchloride; benzene

: 75-07-0
acetaldehyde

: 127-17-3
2-oxo-propionic acid

: 513-86-0, 52217-02-4
3-hydroxy-2-butanon

Conditions

Conditions	Yield
With sodium hydroxide; thiamine diphosphate chloride hydrochloride In methanol at 37℃; for 5.5h;	100%
Vergaerung durch Essigbakterien;
durch Hefe; Ausbeute ist groesser,wenn zu der gaerenden Brenztraubensaeure-Loesung gleich nach Beginn der Gaerung noch Acetalehyd zugesetzt wird;

: 75-07-0
acetaldehyde

: 64-17-5
ethanol

Conditions

Conditions	Yield
With perchloric acid; 9,10-dihydro-10-methylacridine In acetonitrile at 59.9℃; for 1h; Product distribution; other aldehydes and ketones; primary kinetic isotope effects (kH/kD);	100%
With tris(triphenylphosphine)ruthenium(II) chloride; formic acid; tributyl-amine In various solvent(s) for 0.5h; Ambient temperature;	89%
With ammonium chloride; zinc In tetrahydrofuran; water at 20℃; for 0.333333h;	84%

: 7677-24-9
trimethylsilyl cyanide

: 75-07-0
acetaldehyde

: 41309-99-3
2-<(trimethylsilyl)oxy>propanenitrile

Conditions

Conditions	Yield
With Zr(IV) metal-organic framework with 1,4-benzenedicarboxylate in anhydrous form In dichloromethane at 40℃; for 46h; Inert atmosphere; Reflux;	100%
With Eu2(benzene-1,2,3,4,5,6-hexacarboxylate)(H2O)3 In acetonitrile at 20 - 100℃; for 3h;	99%
With {[Zn3(1,2-bis(4-pyridyl)ethene)4(μ-OOCC2H5)4](1,2-bis(4-pyridyl)ethene)(ClO4)2}n In dichloromethane Catalytic behavior; Reagent/catalyst; Solvent;	82%

: 75-07-0
acetaldehyde

: 536-74-3
phenylacetylene

: 73922-81-3, 81555-86-4, 104597-03-7, 5876-76-6
4-phenyl-but-3-yn-2-ol

Conditions

Conditions	Yield
With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at -78 - 20℃; for 2h;	100%
Stage #1: phenylacetylene With n-butyllithium In diethyl ether; hexane at -78℃; for 0.5h; Inert atmosphere; Schlenk technique; Stage #2: acetaldehyde In diethyl ether; hexane at -78 - 20℃; for 1h; Inert atmosphere; Schlenk technique;	98%
Stage #1: phenylacetylene With n-butyllithium In tetrahydrofuran; hexane for 0.5h; Cooling with ice; Stage #2: acetaldehyde In tetrahydrofuran; hexane	87%

: 554-14-3
2-Methylthiophene

: 75-07-0
acetaldehyde

: 19077-07-7
2-methyl-5-(1-(5-methylthiophen-2-yl)ethyl)thiophene

Conditions

Conditions	Yield
With ion-exchange resin Lewatit SPC 108 (acid form) In 1,4-dioxane; water at 20℃; for 1.5h;	100%

: 584-13-4
4-amino-1,2,4-triazole

: 75-07-0
acetaldehyde

: 33761-49-8
4-(Ethylideneamino)-1,2,4-triazole

Conditions

Conditions	Yield
With sulfuric acid In ethanol for 4h; Heating;	100%
With molecular sieve for 3h; Ambient temperature;	39%

: 6089-04-9
3-(tetrahydropyran-2'-yloxy)propyne

: 75-07-0
acetaldehyde

: 14092-30-9
5-<(Tetrahydro-2H-pyran-2-yl)oxy>-3-pentyn-2-ol

Conditions

Conditions	Yield
Stage #1: 3-(tetrahydropyran-2'-yloxy)propyne With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 2h; Stage #2: acetaldehyde In tetrahydrofuran; hexane at -78℃; for 1h; Further stages.;	100%
With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at -78 - 20℃; for 2h;	95%
Stage #1: 3-(tetrahydropyran-2'-yloxy)propyne With n-butyllithium In tetrahydrofuran; hexane at -78 - 0℃; Inert atmosphere; Stage #2: acetaldehyde In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;	89%

: 7677-24-9
trimethylsilyl cyanide

: 554-00-7
2,4-Dichloroaniline

: 75-07-0
acetaldehyde

: 145100-49-8
2-(2,4-Dichloro-phenylamino)-propionitrile

Conditions

Conditions	Yield
With water In dichloromethane for 24h; Ambient temperature;	100%

...Expand

: 4761-34-6
N-Hydroxytryptamine

: 75-07-0
acetaldehyde

: C12H14N2O

Conditions

Conditions	Yield
With acetic acid In methanol for 12h;	100%

: 5344-90-1
2-Aminobenzyl alcohol

: 75-07-0
acetaldehyde

: 59689-24-6
2-methyl-1,4-dihydro-2H-benz[d][1,3]oxazine

Conditions

Conditions	Yield
With calcium chloride In dichloromethane	100%
With magnesium sulfate In tetrahydrofuran at 60℃; for 3h;	75%
In benzene

: 54125-02-9
danishefsky's diene

: 75-07-0
acetaldehyde

: 19185-89-8
2-methyl-2,3-dihydro-4H-pyran-4-one

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In diethyl ether at -70℃; for 1h;	100%
With boron trifluoride diethyl etherate In diethyl ether at -78℃; for 2h;	89%
With boron trifluoride In diethyl ether at -78℃; for 2h; hetero-Diels-Alder reaction;	88%

: 63366-56-3
methylene bis phosphonate de diethyle

: 75-07-0
acetaldehyde

: 123146-81-6
2-ethoxy-2-(2',2'-diethoxy-3',5'-dimethyl-1',4',2'-dioxaphospholanyl)methylene-3,5-dimethyl-1,4,2-dioxaphospholane

Conditions

Conditions	Yield
In neat (no solvent) 1) 20 deg C, 2h, 2) 0.5 mm Hg, 20 deg C;	100%

: 68385-34-2
N-(2-hydroxy-1,1-dimethyl-2-phenylethyl)hydroxylamine

: 75-07-0
acetaldehyde

: 3-hydroxy-2,2,4-trimethyl-5-phenyloxazolidine

Conditions

Conditions	Yield
In ethanol	100%

: 37477-17-1
O-mesitoylhydroxylamine

: 75-07-0
acetaldehyde

: 84298-25-9
mesityloylacetaldoxime

Conditions

Conditions	Yield
With magnesium sulfate In diethyl ether at 0℃; for 82h;	100%

: 129295-70-1
2-(2'-Hydroxy-5'-nitrophenyl)ethylamine hydrochloride

: 75-07-0
acetaldehyde

: 129295-72-3
N,N-Diethyl-2-(2'-hydroxy-5'-nitrophenyl)ethylamine hydrochloride

Conditions

Conditions	Yield
With sodium cyanoborohydride In methanol pH 6-8;	100%

: 2999-46-4
Ethyl isocyanoacetate

: 75-07-0
acetaldehyde

: 55942-37-5
5-Methyl-4,5-dihydro-oxazole-4-carboxylic acid ethyl ester

Conditions

Conditions	Yield
triethylamine; copper(l) chloride In tetrahydrofuran for 10h; Ambient temperature;	100%

: 79618-03-4
(4aR,7R,8aR)-4,4,7-Trimethyl-hexahydro-1-oxa-3-thia-naphthalene

: 75-07-0
acetaldehyde

: 79563-69-2, 112067-00-2, 112067-01-3
1-((2R,4aR,7R,8aR)-4,4,7-Trimethyl-hexahydro-1-oxa-3-thia-naphthalen-2-yl)-ethanol

Conditions

Conditions	Yield
With n-butyllithium 1.) THF, -78 deg C;	100%

: 130857-96-4
1R,2S-N,N-dimethyl-2-phenyl-3-methyl-1,3-diaminoethane

: 75-07-0
acetaldehyde

: 130827-40-6
(1S,2S,3R,4S,5R)-1,2,3,4-Tetramethyl-5-phenyl-imidazolidine

Conditions

Conditions	Yield
In chloroform for 24h; Ambient temperature;	100%

: 136103-76-9
1-mercaptomethyl-2-(α-mercaptoethyl)benzene

: 75-07-0
acetaldehyde

: 136103-74-7
cis-2,4-dimethyl-1,3-dithia-5,6-benzocycloheptene

Conditions

Conditions	Yield
With hydrogenchloride In 1,4-dioxane for 0.25h;	100%

: 97051-77-9
methyl 5-methoxybenzocyclobutene-1-carboxylate

: 75-07-0
acetaldehyde

: 126444-40-4, 126444-58-4
methyl 1-(1-hydroxyethyl)-5-methoxybenzocyclobutene-1-carboxylate

Conditions

Conditions	Yield
With n-butyllithium; diisopropylamine; lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.833333h;	100%

: 151-50-8
potassium cyanide

: 75-07-0
acetaldehyde

: 60-15-1, 156-34-3, 51-64-9, 300-62-9
2-amino-1-phenylpropane

: 3535-04-4
2-<(1-methyl-2-phenylethyl)amino>propanenitrile

Conditions

Conditions	Yield
With sodium hydrogensulfite In methanol; water Ambient temperature;	100%

...Expand

: 75-07-0
acetaldehyde

: 622-30-0
N-benzyl hydroxylalmine

: 243140-08-1
5(Z)-N-ethylidene-1-phenylmethanamine N-oxide

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 1h;	100%
With sodium sulfate In dichloromethane Ambient temperature;	55%

: 75-07-0
acetaldehyde

: 622-30-0
N-benzyl hydroxylalmine

: 20135-15-3, 243140-08-1, 139189-66-5
N-ethylidenebenzylamine N-oxide

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane at 20℃; for 1h; Inert atmosphere;	100%
With magnesium sulfate In dichloromethane at 20℃; for 1h; Inert atmosphere;	100%
With magnesium sulfate In dichloromethane at 20℃; for 1h; Inert atmosphere;	100%

: 75-07-0
acetaldehyde

: 81549-01-1
1-Phenylazo-ethylamine

: 41217-48-5
3,5-dimethyl-1-phenyl-1H-1,2,4-triazole

Conditions

Conditions	Yield
In chloroform Ambient temperature;	100%

: 75-07-0
acetaldehyde

: 86993-52-4
(1S*,2R*)-cis-bicyclo<3.3.0>oct-3,7-diene-2-spiro-4'-<(α,α-bis(phenylsulfenyl))-γ-butyrolactone>

: 86971-75-7
(1S*,2R*)-cis-bicyclo<3.3.0>oct-3,7-diene-2-spiro-4'-<α-(1-hydroxyethyl)-α-(Phenylsulfenyl)-γ-butyrolactone>

Conditions

Conditions	Yield
With ethylmagnesium bromide In tetrahydrofuran; diethyl ether 1.) 0 deg C;	100%
With ethylmagnesium bromide	100%

Acetaldehyde History

Acetaldehyde was first prepared by Scheele in 1774, by the action of manganese dioxide (MnO₂) and sulfuric acid (H₂SO₄) on ethyl alcohol (ethanol, CH₃CH₂OH).
The formation of acetaldehyde by the addition of water to acetylene was observed by Kutscherow in 1881.

Acetaldehyde Specification

The Acetaldehyde, with the CAS registry number 75-07-0 and EINECS registry number 200-001-8, is a kind of colourless clear liquid with the molecular formula of C₂H₄O. It is one of the most important aldehydes, occurring widely in nature and being produced on a large scale industrially. Acetaldehyde can be found naturally in coffee, bread, and ripe fruit, and it is produced by plants as part of their normal metabolism.

The physical properties of Acetaldehyde are as followings: (1)# of Rule of 5 Violations: 0; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 20.875; (5)ACD/KOC (pH 7.4): 20.875; (6)#H bond acceptors: 1; (7)#H bond donors: 0; (8)#Freely Rotating Bonds: 0; (9)Polar Surface Area: 17.07 Å²; (10)Index of Refraction: 1.315; (11)Molar Refractivity: 11.501 cm³; (12)Molar Volume: 58.868 cm³; (13)Polarizability: 4.56×10^-24cm³; (14)Surface Tension: 17.618 dyne/cm; (15)Density: 0.748 g/cm³; (16)Enthalpy of Vaporization: 25.76 kJ/mol; (17)Boiling Point: 18.588 °C at 760 mmHg; (18)Vapour Pressure: 964.536 mmHg at 25°C.

Preparation: The main production method is the oxidation of ethylene via the Wacker process:
2CH₂=CH₂+O₂ → 2CH₃CHO

Uses: It is usually used as a precursor to acetic acid, but this application has declined because it can be made more efficiently from methanol by the Monsanto and Cativa processes. And in terms of condensation reactions, acetaldehyde is an important precursor to pyridine derivatives, pentaerythritol, and crotonaldehyde.

You should be cautious while dealing with this chemical. It is a kind of extremely flammable chemical which irritates to eyes and respiratory system. And there's limited evidence of a carcinogenic effect. Therefore, you had better take the following instructions: Keep away from sources of ignition - No smoking; Wear suitable protective clothing and gloves; Take precautionary measures against static discharges.

You can still convert the following datas into molecular structure:
(1)SMILES: CC=O
(2)InChI: InChI=1/C2H4O/c1-2-3/h2H,1H3
(3)InChIKey: IKHGUXGNUITLKF-UHFFFAOYAB

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	intravenous	800mg/kg (800mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
hamster	LC50	inhalation	17000ppm/4H (17000ppm)		Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979.
hamster	LD50	intratracheal	96mg/kg (96mg/kg)		Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979.
human	TCLo	inhalation	134ppm/30M (134ppm)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.
mammal (species unspecified)	LC50	inhalation	20100mg/m³ (20100mg/m³)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(7), Pg. 54, 1975.
mouse	LC50	inhalation	23gm/m³/4H (23000mg/m³)		Current Toxicology. Vol. 1, Pg. 47, 1993.
mouse	LD50	intraperitoneal	500mg/kg (500mg/kg)		IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 36, Pg. 101, 1985.
mouse	LD50	oral	900mg/kg (900mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981.
mouse	LD50	subcutaneous	560mg/kg (560mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC	Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rabbit	LD50	skin	3540mg/kg (3540mg/kg)		Union Carbide Data Sheet. Vol. 12/13/1963,
rabbit	LDLo	intravenous	300mg/kg (300mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
rabbit	LDLo	subcutaneous	1200mg/kg (1200mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
rat	LC50	inhalation	13300ppm/4H (13300ppm)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA	National Technical Information Service. Vol. OTS0534485,
rat	LD50	oral	661mg/kg (661mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Agents and Actions, A Swiss Journal of Pharmacology. Vol. 4, Pg. 125, 1974.
rat	LD50	subcutaneous	640mg/kg (640mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC	Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rat	LDLo	intraperitoneal	500mg/kg (500mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Biological Chemistry. Vol. 152, Pg. 41, 1944.

Product Name

Acetic aldehyde

Synthetic route

Acetaldehyde History

Acetaldehyde Specification

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