Ammonium carbamate supplier

Name
Ammonium carbamate
EINECS 214-185-2
CAS No. 1111-78-0
Article Data47
CAS DataBase
Density 1.6 g/cm³
Solubility Soluble in water, ethanol
Melting Point 59-61°C (subl.)
Formula CH₃NO₂·H₃N
Boiling Point 251 °C at 760 mmHg
Molecular Weight 78.0708
Flash Point 105.6 °C
Transport Information
Appearance white crystalline solid
Safety 22-24/25
Risk Codes 22
Molecular Structure
Hazard Symbols Xn
Synonyms Ammoniumcarbamate (6CI,7CI);Carbamic acid, monoammonium salt (8CI,9CI);Carbamic acid, ammoniumsalt (1:1);
PSA 66.56000
LogP 0.64730

Synthetic route

: 124-38-9
carbon dioxide

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With ammonia at 0℃; for 8h;	90%
With ammonia
With ammonia; water; urea

: 14066-73-0
benzophenone semicarbazone

A: 110-21-4
hydrazodicarboxamide

B: 16240-68-9
1,5-dibenzhydrylidene-carbonohydrazide

C: 1111-78-0
ammonium carbamate

D: 983-79-9
benzophenone azine

Conditions

Conditions	Yield
bei Erhitzen ueber den Schmelzpunkt;

...Expand

: 556-02-5, 556-03-6, 34537-57-0, 55520-40-6, 96946-98-4, 60-18-4
›Tyr

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With alkaline potassium permanganate

: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

A: 4366-93-2
potassium carbamate

B: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With potassium ammonium Nebenproduktd wird entfernt durch Erwaermen im Vakuum auf 50grad;

: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With ammonia
With ammonia Waermetoenung;
With ethanol; ammonia at 100 - 110℃;

: 56-40-6
glycine

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With alkaline potassium permanganate

: 328-39-2
LEUCINE

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With alkaline potassium permanganate

: 57-13-6
urea

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With phosphate-EDTA-buffer; urea amidohydrolase EC 3.5.1.5 at 25℃; rates of urea amidohydrolase catalyzed hydrolysis; pH 7.0;
With water

: 124-38-9
carbon dioxide

A: 50-00-0
formaldehyd

B: 64-18-6
formic acid

C: 463-77-4
carbamic Acid

D: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With ammonia; water at -258.15℃; bombardment with 1 MeV protons; Further byproducts given;

...Expand

Fe(CO)5: Fe(CO)5

: 1111-78-0
ammonium carbamate

Conditions

Conditions	Yield
With ammonia; water auch bei Sauerstoff-Ausschluss;

: 124-38-9
carbon dioxide

: 7664-41-7
ammonia

: 1111-78-0
ammonium carbamate

: 124-38-9
carbon dioxide

A: 1111-78-0
ammonium carbamate

B: 57-13-6
urea

Conditions

Conditions	Yield
With ammonia at 182℃; under 116262 Torr; for 0.333333h; Conversion of starting material; Industry scale;
With ammonia In water at 182℃; under 116262 Torr; for 0.333333h; Industry scale; Compressed gas(es);
With ammonia at 182℃; under 116262 Torr; for 0.333333h; Conversion of starting material; Industry scale;
With ammonia
With ammonia Product distribution / selectivity;

: 124-38-9
carbon dioxide

A: 7732-18-5
water

B: 1111-78-0
ammonium carbamate

C: 57-13-6
urea

Conditions

Conditions	Yield
With ammonia Product distribution / selectivity; Industry scale;

...Expand

: 50-69-1
D-ribose

: 1111-78-0
ammonium carbamate

: (2R,3R,4R,5R)-2-Amino-tetrahydro-pyran-3,4,5-triol; compound with carbamic acid

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 3h;	94%

: 61-58-5, 13299-15-5, 13299-16-6, 14215-77-1, 14215-78-2, 20789-85-9, 23568-30-1, 25494-04-6, 34339-39-4, 34339-40-7, 34339-46-3, 34339-47-4, 114717-20-3, 114717-21-4, 137491-75-9, 137491-76-0
2-deoxy-D-lyxo-hexopyranose

: 1111-78-0
ammonium carbamate

: 2-deoxy-β-D-lyxo-hexopyranosylammonium carbamate

Conditions

Conditions	Yield
With ammonia In methanol; water at 20℃; for 7h;	94%

: 58-86-6
D-xylose

: 1111-78-0
ammonium carbamate

: (2R,3R,4S,5R)-2-Amino-tetrahydro-pyran-3,4,5-triol; compound with carbamic acid

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 5h;	93%

: 59-23-4
D-Galactose

: 1111-78-0
ammonium carbamate

: (2R,3R,4S,5R,6R)-2-Amino-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol; compound with carbamic acid

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 15h;	93%

: 1111-78-0
ammonium carbamate

: 123-54-6
acetylacetone

: 1118-66-7
4-Aminopent-3-en-2-one

Conditions

Conditions	Yield
In methanol at 20℃; for 2h;	93%

: 1111-78-0
ammonium carbamate

: 16712-16-6, 64165-14-6, 65387-22-6, 70179-79-2, 540-69-2
ammonium formate

Conditions

Conditions	Yield
With 5% Pd/C; hydrogen In ethanol; water at 20℃; under 20627.1 Torr; for 8h; Kinetics; Catalytic behavior; Solvent; Pressure; Reagent/catalyst; Temperature; Time;	91.7%
With 5%-palladium/activated carbon; hydrogen In ethanol; water at 20℃; under 20627.1 Torr; for 8h; Solvent; Temperature; Pressure; Time; Reagent/catalyst;	91.7%

: 2280-44-6
D-Glucose

: 1111-78-0
ammonium carbamate

: β-D-glucopyranosylammonium carbamate

Conditions

Conditions	Yield
In methanol at 37℃; for 16h;	91%

: 63-29-6, 487-44-5, 575-64-4, 14362-29-9, 18281-92-0, 26623-21-2
D-glucurono-6,3-lactone

: 1111-78-0
ammonium carbamate

: (β-D-glucopyranosylammonium)uronamide carbamate

Conditions

Conditions	Yield
In methanol at 20℃; for 16h;	89.5%

: 1111-78-0
ammonium carbamate

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 35342-88-2
N,O-bis<(trimethylsilyl)oxy>acetamide

Conditions

Conditions	Yield
With sulfuric acid In chloroform at 35 - 40℃; for 15h;	89.1%
With sulfuric acid In chloroform at 35 - 40℃; for 12h; Product distribution; other temperatures; other reaction time; other solvents: CCl4, THF, DMF.;

: 50-99-7
D-glucose

: 1111-78-0
ammonium carbamate

: β-D-glucopyranosylammonium carbamate

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 24h;	89%

: 60839-94-3
2-fluoro-methylthiobenzene

: 1111-78-0
ammonium carbamate

A: 1280126-02-4
(fluoromethyl)(imino)(phenyl)-λ6-sulfanone

B: N-[oxidophenyl(fluoromethyl)- λ4-sulfanylidene]-acetamide

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene In methanol at 20℃; for 0.5h;	A 89% B n/a

...Expand

: 1111-78-0
ammonium carbamate

: 81931-98-8
1-<(Difluoromethyl)thio>-4-methoxybenzene

A: (difluoromethyl)(imino)(4-methoxyphenyl)-λ6-sulfanone

B: C10H11F2NO3S

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene In methanol at 20℃; for 12h;	A 88% B n/a

...Expand

: 1111-78-0
ammonium carbamate

: 499-40-1, 554-91-6, 585-99-9, 4233-70-9, 5077-31-6, 5188-47-6, 6614-35-3, 7286-49-9, 13117-25-4, 17296-19-4, 19940-03-5, 20113-42-2, 21216-58-0, 25538-26-5, 28447-39-4, 34097-00-2, 40246-35-3, 40592-71-0, 52611-34-4, 71184-87-7, 77881-87-9, 96844-88-1, 117249-74-8, 117249-83-9, 117249-87-3, 117249-92-0, 117249-96-4, 117250-05-2, 117250-10-9, 117250-14-3, 117250-19-8, 117306-23-7, 117306-27-1, 117306-32-8, 117306-37-3, 117306-42-0, 117306-47-5, 117469-04-2, 117469-05-3, 117469-10-0
melibiose

: C12H23NO10*CH3NO2

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 10h;	87%

: 1111-78-0
ammonium carbamate

: 554-91-6
O6-β-D-Glucopyranosyl-D-glucose

: C12H23NO10*CH3NO2

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 12h;	85%

: 1111-78-0
ammonium carbamate

: 63-42-3
D-(+)-lactose

: (2S,3R,4S,5R,6R)-2-((2R,3S,4R,5R,6R)-6-Amino-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol; compound with carbamic acid

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 20h;	85%

: 7512-17-6
2-acetamido-2-deoxy-D-glucose

: 1111-78-0
ammonium carbamate

: 2-acetamido-2-deoxy-β-D-glucopyranosylammonium carbamate

Conditions

Conditions	Yield
In methanol; water at 5 - 37℃; for 64h;	83%

: 1111-78-0
ammonium carbamate

: 528-50-7
cellobiose

: (2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-6-Amino-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol; compound with carbamic acid

Conditions

Conditions	Yield
With ammonium hydroxide In methanol at 37℃; for 25h;	82%

: 61-58-5, 13299-15-5, 13299-16-6, 14215-77-1, 14215-78-2, 20789-85-9, 23568-30-1, 25494-04-6, 34339-39-4, 34339-40-7, 34339-46-3, 34339-47-4, 114717-20-3, 114717-21-4, 137491-75-9, 137491-76-0
2-deoxy-D-arabino-hexopyranose

: 1111-78-0
ammonium carbamate

: 2-deoxy-β-D-arabino-hexopyranosylammonium carbamate

Conditions

Conditions	Yield
In methanol at 20℃; for 48h;	82%

: 1535-67-7
difluoromethyl phenyl sulfide

: 1111-78-0
ammonium carbamate

A: 1333375-53-3
(difluoromethyl)(imino)(phenyl)-λ6-sulfanone

B: N-acetyl S-difluoromethyl-S-phenyl sulfoximine

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene In methanol at 20℃; for 8h;	A 82% B n/a

...Expand

: 6556-12-3, 489-91-8, 528-16-5, 552-12-5, 577-46-8, 643-33-4, 2240-07-5, 6294-16-2, 10133-02-5, 18402-78-3, 18968-14-4, 21179-08-8, 23018-83-9, 33599-45-0, 33599-46-1, 46171-67-9, 46171-69-1, 46172-26-3, 70021-34-0, 71031-08-8, 104195-06-4, 106499-29-0, 124817-72-7
D-glucuronic acid

: 1111-78-0
ammonium carbamate

: C6H11NO6*CH3NO2*H3N

Conditions

Conditions	Yield
With ammonia In methanol; water at 20℃; for 48h;	81%

: 65325-64-6
1-[(fluoromethyl)sulfanyl]-4-methylbenzene

: 1111-78-0
ammonium carbamate

A: (fluoromethyl)(imino)(p-tolyl)-λ6-sulfanone

B: C10H12FNO2S

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene In methanol at 20℃; for 0.5h;	A 80% B n/a

...Expand

: 1111-78-0
ammonium carbamate

: 93-91-4
1-phenylbutan-1,3-dione

: 23652-90-6
(2Z)-3-amino-1-phenylbut-2-en-1-one

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	75%

: 151-50-8
potassium cyanide

: 1111-78-0
ammonium carbamate

: 142924-43-4
(S)-N-(3-oxo-1-phenylbutan-2-yl)acetamide

: (S)-5-(1-acetamido-2-phenyl)ethyl-5-methylimidazolidine-2,4-dione

Conditions

Conditions	Yield
With ammonium carbonate In ethanol; water at 45℃; for 3h; sonification;	74%

...Expand

: 75-77-4
chloro-trimethyl-silane

: 1111-78-0
ammonium carbamate

: 58078-34-5
trimethylsilyl carbamate

Conditions

Conditions	Yield
In chloroform at 20℃;	73%

: 151-50-8
potassium cyanide

: 1111-78-0
ammonium carbamate

: 3-acetamido-4-(4-acetoxyphenyl)butan-2-one

: N-[2-(4-hydroxy-phenyl)-1-(4-methyl-2,5-dioxo-imidazolidin-4-yl)-ethyl]-acetamide

Conditions

Conditions	Yield
With ammonium carbonate In ethanol; water at 45℃; for 3h; sonification;	73%

...Expand

: 1111-78-0
ammonium carbamate

: 76043-69-1
2,2-dichloro-3-phenylpropionaldehyde

: 18166-56-8
α-chloro-β-phenylpropionamide

Conditions

Conditions	Yield
With 2-(2,4,6-trichlorophenyl)-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazol-4-ylium tetrafluoroborate In tetrahydrofuran at 20℃; for 0.75h;	73%

: 530-26-7
D-Mannose

: 1111-78-0
ammonium carbamate

: β-D-mannopyranosylammonium carbamate

Conditions

Conditions	Yield
In methanol at 20℃; for 24h;	71%

: 1111-78-0
ammonium carbamate

: 28637-56-1
2,2-dimethyl-5,6,7,8-tetrahydro-4H-benzo[d][1,3]dioxin-4-one

: 141772-31-8
2-fluoro-4-chloro-5-methoxycarbonylaniline

: methyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate

Conditions

Conditions	Yield
Stage #1: 2,2-dimethyl-5,6,7,8-tetrahydro-4H-benzo[d][1,3]dioxin-4-one; 2-fluoro-4-chloro-5-methoxycarbonylaniline In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 10h; Stage #2: ammonium carbamate In methanol at 60℃; for 12h; Stage #3: With orthoformic acid triethyl ester for 12h; Reflux;	69%

...Expand

: (3-phenylpropyl)(difluoromethyl)sulfide

: 1111-78-0
ammonium carbamate

A: imino(3-phenylpropyl)(difluoromethyl)-λ6-sulfanone

B: C12H15F2NO2S

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene In methanol at 20℃; for 3h;	A 68% B n/a

...Expand

Ammonium carbamate Consensus Reports

Reported in EPA TSCA Inventory.

Ammonium carbamate Specification

Ammonium carbamate is an organic compound with the formula CH₃NO₂·H₃N, and its systematic name is the same with the product name. With the CAS registry number 1111-78-0, it is also named as Carbamic acid, ammoniumsalt (1:1). It belongs to the product category of Industrial/Fine Chemicals. Its EINECS number is 214-185-2. In addition, the molecular weight is 78.07. This chemical is stable at common pressure and temperature, and it should be sealed and stored in a cool and dry place. Moreover, it should be protected from oxides, acids, alkali and water. This chemical will decompose slowly in the air and release ammonia, and it can slightly volatilize at room temperature and completely sublimate and decompose at the temperature of 50 °C. Moreover, it will turn into ammonium carbonate when placed in damp air or aqueous solution. When heated, it will produce urea. This chemical can be used as aluminum phosphide intermediate, and it is also used in medicine.

Physical properties of Ammonium carbamate are: (1)ACD/LogP: -1.194; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.94; (4)ACD/LogD (pH 7.4): -3.73; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 40.54 Å²; (13)Flash Point: 105.6 °C; (14)Enthalpy of Vaporization: 53.77 kJ/mol; (15)Boiling Point: 251 °C at 760 mmHg; (16)Vapour Pressure: 0.00662 mmHg at 25°C.

Preparation: this chemical can be prepared by anhydrous liquid ammonia and drikold. Moreover, 400 mL liquid ammonia can produce 200-300 g Ammonium carbamate.

Uses of Ammonium carbamate: it can be used to produce trimethylsilyl carbamate at the temperature of 20 °C. It will need solvent CHCl₃. The yield is about 73%.

Ammonium carbamate can be used to produce trimethylsilyl carbamate at the temperature of 20 °C

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed. You should not breathe dust. When using it, you must avoid contact with eyes.

You can still convert the following datas into molecular structure:
(1)SMILES: [O-]C(=O)N.[NH4+]
(2)Std. InChI: InChI=1S/CH3NO2.H3N/c2-1(3)4;/h2H2,(H,3,4);1H3
(3)Std. InChIKey: BVCZEBOGSOYJJT-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	77mg/kg (77mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	American Journal of Veterinary Research. Vol. 29, Pg. 897, 1968.
rat	LD50	intravenous	39mg/kg (39mg/kg)		American Journal of Veterinary Research. Vol. 29, Pg. 897, 1968.
rat	LD50	oral	> 681mg/kg (681mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER	National Technical Information Service. Vol. OTS0535595,

Product Name

Ammonium carbamate

Synthetic route

Ammonium carbamate Consensus Reports

Ammonium carbamate Specification

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