Furan supplier | CasNO.110-00-9

Name
Furan
EINECS 203-727-3
CAS No. 110-00-9
Article Data303
CAS DataBase
Density 0.942 g/cm³
Solubility insoluble in water
Melting Point -85.6 °C
Formula C₄H₄O
Boiling Point 31.36 °C at 760 mmHg
Molecular Weight 68.0752
Flash Point -35 °C
Transport Information UN 2811 6.1/PG 2
Appearance clear colorless liquid
Safety 53-45-61
Risk Codes 45-12-19-20/22-38-48/22-52/53-68
Molecular Structure
Hazard Symbols T, F+
Synonyms Divinyleneoxide;Furfuran;Oxacyclopentadiene;Oxole;Tetrole;
PSA 13.14000
LogP 1.27960

Synthetic route

: 98-01-1
furfural

: 110-00-9
furan

Conditions

Conditions	Yield
With carbon dioxide; palladium/alumina at 145℃; under 45004.5 Torr; for 6.5h; Green chemistry;	99%
With carbon dioxide; 5% Pd(II)/C(eggshell) at 250℃; under 112511 Torr; Supercritical conditions;	98%
With palladium nanoparticles deposited on porous SBA-15 In cyclohexane at 150℃; for 24h; Molecular sieve;	96%

: 82660-71-7
2',6'-exo-spirodioxatricyclo<5.2.1.02,6>dec-8'-en-3'-one>

A: 110-00-9
furan

B: 5732-90-1
1-oxaspiro<4.4>non-3-en-2-one

Conditions

Conditions	Yield
In tetrahydrofuran at 130℃;	A n/a B 98%

: [3-(1-Benzylamino-pentyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-methanol

A: 110-00-9
furan

B: (Z)-4-Benzylamino-oct-2-en-1-ol

Conditions

Conditions	Yield
at 120℃; for 0.25h; Irradiation;	A n/a B 98%

: {3-[1-(4-Methoxy-benzylamino)-pentyl]-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl}-methanol

A: 110-00-9
furan

B: (Z)-4-(4-Methoxy-benzylamino)-oct-2-en-1-ol

Conditions

Conditions	Yield
at 120℃; for 0.25h; Irradiation;	A n/a B 98%

: [3-(1-Dibenzylamino-pentyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-methanol

A: 110-00-9
furan

B: (Z)-4-Dibenzylamino-oct-2-en-1-ol

Conditions

Conditions	Yield
at 140℃; for 0.166667h; Irradiation;	A n/a B 98%

: {3-[4-Benzyloxy-1-(4-methoxy-benzylamino)-butyl]-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl}-methanol

A: 110-00-9
furan

B: (Z)-7-Benzyloxy-4-(4-methoxy-benzylamino)-hept-2-en-1-ol

Conditions

Conditions	Yield
at 120℃; for 0.25h; Irradiation;	A n/a B 98%

: [3-(4-Benzyloxy-1-dibenzylamino-butyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-methanol

A: 110-00-9
furan

B: (Z)-7-Benzyloxy-4-dibenzylamino-hept-2-en-1-ol

Conditions

Conditions	Yield
at 140℃; for 0.166667h; Irradiation;	A n/a B 98%

: 82660-72-8
2',6'-exo-spirodioxatricyclo<5.2.1.02,6>dec-8'-en-3'-one>

A: 110-00-9
furan

B: 4435-19-2
1-oxa-spiro[4.5]dec-3-en-2-one

Conditions

Conditions	Yield
In tetrahydrofuran at 130℃; under 7 Torr;	A n/a B 97%

: 930-22-3
epoxybutene

A: 1708-29-8
2,5-dihydrofuran

B: 110-00-9
furan

C: 123-73-9
trans-Crotonaldehyde

Conditions

Conditions	Yield
tetra-n-heptylammonium iodide; tributyltin iodide In para-xylene at 109 - 117℃; for 0.75h;	A 96.1% B n/a C n/a

...Expand

: 25414-22-6
2-methoxyfuran

: 123-73-9
trans-Crotonaldehyde

dichloroacetic acid (DCA): dichloroacetic acid (DCA)

: 346440-54-8
(2S,5S)-5-benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one

: 110-00-9
furan

Conditions

Conditions	Yield
In diethyl ether; chloroform	95%

...Expand

: 22037-28-1
3-bromofurane

A: 110-00-9
furan

B: 6142-87-6
furan-3-d

Conditions

Conditions	Yield
With n-butyllithium; deuteromethanol In tetrahydrofuran; cyclohexane at -65℃;	A 6% B 93%

: 4208-64-4
1-(2-furyl)ethanol

: 110-00-9
furan

Conditions

Conditions	Yield
With 1,10-Phenanthroline; oxygen; copper diacetate; silver nitrate; sodium hydroxide In dimethyl sulfoxide at 140℃; under 3750.38 Torr; for 12h; Autoclave; Green chemistry;	91%

: 95641-44-4
C13H13NO4

A: 110-00-9
furan

B: 1,3,5-trimethyl-4H-furo<3,4-c>pyrrole-4,6(5H)-dione

Conditions

Conditions	Yield
at 500℃; under 0.01 Torr; Irradiation;	A n/a B 90%

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

: 110-00-9
furan

Conditions

Conditions	Yield
With 1,10-Phenanthroline; oxygen; copper diacetate; silver nitrate; sodium hydroxide In dimethyl sulfoxide at 140℃; under 3750.38 Torr; for 12h; Autoclave; Green chemistry;	90%

: 124031-50-1
(1R,2S,5R,6S,7S)-5-(2'-oxo-1'-propyl)-4,10-dioxatricyclo<5.2.1.O2,6>dec-8-ene

A: 110-00-9
furan

B: 124031-52-3
(R)-2-(2'-oxo-1'-propyl)-2,5-dihydrofuran

Conditions

Conditions	Yield
at 500℃; under 0.01 Torr; flash termolyses, contact time = 50 ms;	A n/a B 82%

: 148066-39-1
2-Furan-2-yl-4-hydroxy-6-oxo-4-phenyl-cyclohexanecarboxylic acid ethyl ester

A: 110-00-9
furan

B: 148066-43-7
ethyl 3-hydroxy-[1,1'-biphenyl]-4-carboxylate

Conditions

Conditions	Yield
With perchloric acid In benzene for 10h; Heating;	A n/a B 82%

: 124031-49-8
(1R,2S,5R,6S,7S)-5-cyanomethyl-4,10-dioxatricyclo<5.2.1.O2,6>dec-8-ene

A: 110-00-9
furan

B: 124031-51-2
(R)-2-cyanomethyl-2,5-dihydrofuran

Conditions

Conditions	Yield
at 500℃; under 0.01 Torr; flash termolyses, contact time = 50 ms;	A n/a B 80%

: 24736-85-4
diethyl 7-oxabicyclo[2.2.1]hepta-2(3),5(6)-diene-2,3-dicarboxylate

: 62-53-3
aniline

A: 110-00-9
furan

B: diethyl (Z)-2-(phenylamino)but-2-enedioate

Conditions

Conditions	Yield
In neat (no solvent) at 90℃; for 6h; Solvent; Temperature; Schlenk technique; Green chemistry;	A n/a B 77%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 110-00-9
furan

C: 534-22-5
2-methylfuran

D: 98-00-0
(2-furyl)methyl alcohol

Conditions

Conditions	Yield
With hydrogen In methanol at 119.84℃; under 7500.75 Torr; for 1h; Catalytic behavior; Solvent; Reagent/catalyst; Autoclave;	A 6.2% B 8.9% C 7.7% D 75.5%
With hydrogen In isopropyl alcohol at 180℃; under 15001.5 Torr; for 5h; Kinetics; Catalytic behavior; Time; Autoclave; Sealed tube;	A 13% B 22% C 54% D 8%
With hydrogen at 250℃; under 760.051 Torr;	A 10.2% B 13.5% C 38.6% D 19%

...Expand

: 98-01-1
furfural

A: 110-00-9
furan

B: 534-22-5
2-methylfuran

Conditions

Conditions	Yield
With hydrogen at 210℃; Catalytic behavior; Temperature;	A 24.5% B 75.4%
With nickel supported catalyst In methanol; water at 260℃; under 7500.75 Torr; for 4h; Reagent/catalyst; Inert atmosphere; Autoclave;	A 58% B 31%
With hydrogen; palladium on activated charcoal at 200℃; Product distribution; other catalysts, other temperatures, different ratios of H2, other selectivity;

: 452-51-7, 13046-70-3, 29780-54-9, 36792-87-7, 36792-88-8, 113890-35-0, 113890-38-3
D-2-deoxyribose

A: 110-00-9
furan

B: 75-07-0
acetaldehyde

C: 141-46-8
Glycolaldehyde

Conditions

Conditions	Yield
at 358℃; for 0.000833333h; Product distribution; Curie-point pyrolysis;	A 15.3% B 74% C 2%

...Expand

: 110-91-8
morpholine

: 24736-85-4
diethyl 7-oxabicyclo[2.2.1]hepta-2(3),5(6)-diene-2,3-dicarboxylate

A: 110-00-9
furan

B: 116308-60-2
diethyl (Z)-2-(morpholino)-2-butenedioate

Conditions

Conditions	Yield
In neat (no solvent) at 90℃; for 0.0166667h; Schlenk technique; Green chemistry;	A n/a B 73%

...Expand

: 98-01-1
furfural

A: 110-00-9
furan

B: 534-22-5
2-methylfuran

C: 98-00-0
(2-furyl)methyl alcohol

Conditions

Conditions	Yield
With hydrogen In methanol at 119.84℃; for 1h; Catalytic behavior; Solvent; Reagent/catalyst; Autoclave;	A 13.4% B 10.3% C 70.7%
With hydrogen at 210℃;	A 56.6% B 11.5% C 16.2%
With hydrogen In isopropyl alcohol at 240℃; under 18751.9 Torr; for 1h; Catalytic behavior; Temperature;	A 39% B 7.3% C 25.9%

...Expand

: 6117-80-2
1,4-butenediol

: 110-00-9
furan

Conditions

Conditions	Yield
With oxygen; palladium diacetate; copper (I) acetate at 40℃; for 20h;	70%

: 82698-71-3
4-(3,6-Dihydro-[1,2]oxazin-2-yl)-benzoic acid methyl ester

A: 110-00-9
furan

B: 23351-08-8
1-(4-(methyl carboxylate) phenyl) pyrrole

C: 619-45-4
4-methoxycarbonyl aniline

Conditions

Conditions	Yield
In methanol Irradiation;	A n/a B 70% C 24%

...Expand

: 24736-85-4
diethyl 7-oxabicyclo[2.2.1]hepta-2(3),5(6)-diene-2,3-dicarboxylate

: 92-54-6
4-phenyl-1-piperazine

A: 110-00-9
furan

B: diethyl 2-(4-phenylpiperazin-1-yl)fumarate

Conditions

Conditions	Yield
In neat (no solvent) at 90℃; for 0.0166667h; Schlenk technique; Green chemistry;	A n/a B 70%

...Expand

: 489-91-8, 528-16-5, 552-12-5, 577-46-8, 643-33-4, 2240-07-5, 6294-16-2, 10133-02-5, 18402-78-3, 18968-14-4, 21179-08-8, 23018-83-9, 33599-45-0, 33599-46-1, 46171-67-9, 46171-69-1, 46172-26-3, 70021-34-0, 71031-08-8, 104195-06-4, 106499-29-0, 124817-72-7
D-galacturonic acid

A: 110-00-9
furan

B: 98-01-1
furfural

C: 141-46-8
Glycolaldehyde

D: 67-64-1
acetone

Conditions

Conditions	Yield
at 358℃; for 0.000833333h; Product distribution; Curie-point pyrolysis;	A 3.2% B 69.8% C 3.1% D 8.6%

...Expand

: 530-26-7
D-Mannose

A: 110-00-9
furan

B: 98-01-1
furfural

C: 141-46-8
Glycolaldehyde

D: 116-09-6
hydroxy-2-propanone

Conditions

Conditions	Yield
at 358℃; for 0.000833333h; Product distribution; Curie-point pyrolysis;	A 2.2% B 63.4% C 18.4% D 7.2%

...Expand

: 110-00-9
furan

: 108-31-6
maleic anhydride

: 6118-51-0
exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

Conditions

Conditions	Yield
In neat (no solvent, solid phase) for 1h; Diels-Alder Cycloaddition; Milling;	100%
In toluene at 110℃; for 24h; Diels-Alder Cycloaddition; Reflux; stereospecific reaction;	100%
at 25℃; for 16h; Diels-Alder reaction;	98%

: 110-00-9
furan

: 109-99-9
tetrahydrofuran

Conditions

Conditions	Yield
With 3% Pd/C; hydrogen In isopropyl alcohol at 219.84℃; under 25858.1 Torr; for 5h; Inert atmosphere;	100%
With hydrogen; acetic acid In water at 39.84℃; for 2h; Inert atmosphere;	98%
With ruthenium; hydrogen; 1-butyl-3-methylimidazolium Tetrafluoroborate at 25℃; under 22502.3 Torr; for 36h; Autoclave; chemoselective reaction;	95%

: 110-00-9
furan

: 108-31-6
maleic anhydride

: 5426-09-5
7-oxanorborn-5-ene-2,3-dicarboxylic anhydride

Conditions

Conditions	Yield
In diethyl ether Diels-Alder reaction;	100%
In diethyl ether at 20℃; for 6h; Diels-Alder Cycloaddition;	98%
In toluene at 20℃; for 72h;	97%

: 110-00-9
furan

: 1191-95-3
cyclobutanone

: 131041-44-6
1-(furan-2-yl)cyclobutan-1-ol

Conditions

Conditions	Yield
Stage #1: furan With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran; hexanes at -78℃; for 1h; Inert atmosphere; Stage #2: cyclobutanone In tetrahydrofuran; hexanes at -78℃; for 1h; Inert atmosphere; Stage #3: With ammonium chloride In tetrahydrofuran; hexanes; water	100%
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane at 0 - 20℃; for 4h; Inert atmosphere; Stage #2: cyclobutanone In tetrahydrofuran; hexane at 0℃; for 1h; Inert atmosphere;	82%
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 3h; Inert atmosphere; Stage #2: cyclobutanone In tetrahydrofuran; hexane at -78 - 20℃; for 3h; Inert atmosphere;	71%

: 110-00-9
furan

: 6773-29-1
dimethyl diazomalonate

: 120508-09-0
2-((Z)-4-Oxo-but-2-enylidene)-malonic acid dimethyl ester

Conditions

Conditions	Yield
With rhodium(II) acetate at 20℃; for 96h;	100%

: 110-00-9
furan

: 67132-63-2
Se-methyl heptaneselenoate

: 5466-40-0
1-furan-2-yl-heptan-1-one

Conditions

Conditions	Yield
With copper (I) trifluoromethane sulfonate benzene In benzene for 0.25h; Ambient temperature;	100%
With <(CF3SO3Cu)2PhH>; calcium carbonate In benzene for 0.25h; Ambient temperature; Yield given;

: 110-00-9
furan

: 136035-18-2
ethyl bromopyruvate tert-butoxycarbonylhydrazone

: 136035-33-1
t-Butyl ethyl 1,4,4a,7a-tetrahydrofuro<3,2-c>pyridazine-1,3-dicarboxylate

Conditions

Conditions	Yield
With sodium carbonate In dichloromethane for 16h; Ambient temperature;	100%

: 110-00-9
furan

: 107-13-1
acrylonitrile

: 53750-68-8
5-cyano-7-oxabicyclo<2.2.1>hept-2-ene

Conditions

Conditions	Yield
With zinc(II) iodide at 40℃; for 48h;	100%
With zinc(II) chloride at 20℃; for 16h;	90%
Stage #1: acrylonitrile With zinc(II) chloride at 20℃; for 0.166667h; Stage #2: furan at 20℃; for 14h;	83%

: 110-00-9
furan

: 1026360-69-9
(Phenyl) iodonium triflate

: 573-57-9
1,4-epoxy-1,4-dihydronaphthalene

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In dichloromethane for 0.166667h; Ambient temperature;	100%
With tetrabutyl ammonium fluoride In tetrahydrofuran; toluene at 20℃; for 0.5h;	64%

: 110-00-9
furan

: <4-Methyl-6-(trimethylsilyl)phenyl>(phenyl) iodonium triflate

: 6-Methyl-1,4-dihydronaphthalene-1,4-endo-oxide

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In dichloromethane Ambient temperature;	100%

: 110-00-9
furan

: <2-Methyl-6-(trimethylsilyl)phenyl>(phenyl) iodonium triflate

: 5-Methyl-1,4-dihydronaphthalene-1,4-endo-oxide

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In dichloromethane Ambient temperature;	100%

: 110-00-9
furan

: 98081-82-4
methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate

: (1R,3R,4S,5S)-3-(2,6-Dichloro-phenyl)-8-oxa-2-aza-tricyclo[3.2.1.02,4]oct-6-ene-4-carboxylic acid methyl ester

Conditions

Conditions	Yield
In tetrahydrofuran for 168h; Ambient temperature;	100%

: 110-00-9
furan

: 1026471-76-0
(phenyl)[2,4,5-tris(trimethylsilyl)phenyl]iodonium triflate

: 220300-23-2
1,4-endoxy-1,4-dihydro-6,7-bis(trimethylsilyl)naphthalene

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 20℃; for 0.333333h;	100%
With tetrabutyl ammonium fluoride; diisopropylamine In tetrahydrofuran; dichloromethane for 0.166667h; Ambient temperature; Yield given;
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃;	600 mg

: 110-00-9
furan

: (5-(methoxycarbonyl)-2-(trimethylsilyl)phenyl)(phenyl)iodonium trifluoromethanesulfonate

: 232264-73-2
11-oxa-tricyclo[6.2.1.0(2,7)]undeca-2,4,6,9-tetraene-4-carboxylic acid methyl ester

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 0℃; for 0.5h;	100%

: 110-00-9
furan

: methyl 2,4,6-tri(tert-butyl)phenylglyoxylate

: 6-methoxycarbonyl-endo-6-(2',4',6'-tri(tert-butyl)phenyl)-2,7-dioxabicyclo[3.2.0]hept-3-ene

Conditions

Conditions	Yield
In benzene Cycloaddition; UV-irradiation;	100%

: 110-00-9
furan

: 86958-27-2
5,5,5',5'-Tetramethyl-5H,5'H-[3,3']bipyrazolyl

A: 68470-88-2
2,7-dimethyl-octa-2,6-dien-4-yne

B: 86958-28-3, 87036-98-4
(1S,5S,6S)-6-(4-Methyl-pent-3-en-1-ynyl)-2-oxa-bicyclo[3.1.0]hex-3-ene

C N2: N2

Conditions

Conditions	Yield
In various solvent(s) at 12℃; Irradiation; pyrex, Philips HPK 125;	A 100% B 68% C n/a

...Expand

: 110-00-9
furan

: 104-87-0
4-methyl-benzaldehyde

: 224962-61-2
2-[α-(4-tolyl)-α-hydroxymethyl]furan

Conditions

Conditions	Yield
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane for 1h; Reflux; Inert atmosphere; Stage #2: 4-methyl-benzaldehyde In tetrahydrofuran; hexane at 20℃; for 0.166667h;	100%
Stage #1: furan With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In hexane for 0.5h; Metallation; lithiation; Heating; Stage #2: 4-methyl-benzaldehyde In tetrahydrofuran; hexane at 20℃; for 0.5h; Substitution;	84%
Stage #1: furan With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane at 0℃; for 1h; Stage #2: 4-methyl-benzaldehyde In tetrahydrofuran; diethyl ether; hexane at 0℃; for 0.25h;	56%

: 110-00-9
furan

: Phenyl[2-(trimethylsilyl)phenyl]iodonium trifluoromethanesulfonate

: 573-57-9
1,4-dihydronaphthalene-1,4-epoxide

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 20℃; for 0.5h; cycloaddition; elimination;	100%

: 110-00-9
furan

: [2-methyl-6-(trimethylsilyl)phenyl](phenyl)iodonium triflate

: 19061-32-6
3-methyl-11-oxatricyclo[6.2.1.02,7]undeca-2(7)3,5,9-tetraene

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 20℃; for 0.5h; cycloaddition; elimination;	100%

: 110-00-9
furan

: [4-methyl-2-(trimethylsilyl)phenyl](phenyl)iodonium triflate

: 19061-31-5
1,4-dihydro-1,4-epoxy-6-methylnaphthalene

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 20℃; for 0.5h; cycloaddition; elimination;	100%

: 110-00-9
furan

: 328119-67-1
2-azidoacrylic acid benzyl ester

: benzyl 8-oxa-2-azatricyclo[3.2.1.02,4]oct-6-ene-4-carboxylate

Conditions

Conditions	Yield
Stage #1: 2-azidoacrylic acid benzyl ester In toluene at 110℃; Stage #2: furan In toluene at 20℃; for 168h; Diels-Alder reaction; Further stages.;	100%

: 110-00-9
furan

: 497-38-1, 2630-41-3
(1S,4R)-bicyclo[2.2.1]heptan-2-one

: (1S,2R,4R)-2-endo-hydroxy-2-exo-(2'-furyl)bicyclo-[2.2.1]heptane

Conditions

Conditions	Yield
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 1h; Stage #2: (1S,4R)-bicyclo[2.2.1]heptan-2-one In tetrahydrofuran; hexane at 20℃; for 6h;	100%
With n-butyllithium In tetrahydrofuran at 20℃; for 18h;	100%

: 110-00-9
furan

: 541-59-3
maleiimide

: 6253-28-7, 19878-26-3, 42074-03-3
3,6-epoxy-1,2,3,6-tetrahydrophthalimide

Conditions

Conditions	Yield
In diethyl ether Diels-Alder reaction;	100%
In diethyl ether at 100℃; for 8h; Autoclave;	99%
In diethyl ether at 100℃; Inert atmosphere; Sealed tube;	99%

: 110-00-9
furan

: 7423-55-4
3-maleimidepropionic acid

: 3-((3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-epoxyisoindol-2-yl)propanoic acid

Conditions

Conditions	Yield
In chloroform at 38℃; for 120h;	100%
In chloroform at 35℃; for 336000h; Diels-Alder reaction;	74%
Stage #1: furan; 3-maleimidepropionic acid In chloroform Darkness; Heating; Stage #2: In methanol; ethyl acetate at 45℃; for 0.25h;	65%

: 110-00-9
furan

: C6H16N2*2C9H18N(1-)*C4H9Na*Mg(2+)

: C6H16N2*C4H3NaO*(C4H3O)2Mg

Conditions

Conditions	Yield
In hexane at 20℃; for 1h;	100%

: 110-00-9
furan

: 2695-48-9
8-Bromo-1-octene

: 2-(oct-7-enyl)furan

Conditions

Conditions	Yield
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 5h; Stage #2: 8-Bromo-1-octene In tetrahydrofuran; hexane at -78 - 20℃;	100%
Stage #1: furan With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 4h; Stage #2: 8-Bromo-1-octene In tetrahydrofuran; hexane at 20℃; Further stages.;

: 110-00-9
furan

: 81971-46-2
[Rh(H)(Ph)(η5-pentamethylcyclopentadienyl)(PMe3)]

: 161301-05-9
(C5Me5)Rh(PMe3)(2-furanyl)H

Conditions

Conditions	Yield
In hexane N2-atmosphere; stirring (60°C, 23 h); evapn. (vac.);	100%

: 110-00-9
furan

: [Ru(1,5-cyclooctadiene)(1,3,5-cyclooctatriene)]

: 554-70-1
triethylphosphine

: 656260-97-8
[Ru(1-5-η5-C8H11)(2-furyl)(PEt3)2]

Conditions

Conditions	Yield
In hexane (N2); standard Schlenk technique; hexane and PEt3 were added via syringeto mixt. of Ru complex and ligand; mixt. was stirred at room temp. for 20 h; volatiles evapd. with oil diffusion pump; crystd. from hexane at -30°C; recrystd. (pentane);	100%

...Expand

: 110-00-9
furan

: 252054-91-4
10-(trimethylsilyl)phenanthren-9-yl trifluoromethanesulfonate

: 1,4-dihydro-1,4-epoxytriphenylene

Conditions

Conditions	Yield
With cesium fluoride In acetonitrile at 40℃; for 16h; Inert atmosphere;	100%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 2h;	81%

: 110-00-9
furan

: 1136845-05-0
6-bromo-2,5,8-trimethoxy-4-methylquinoline

: 1136845-02-7
5-aza-8-methyl-6,9,10-Dimethoxy-1,4-dihydro-1,4-epoxyanthracene

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at -75℃; for 3h;	100%

Furan Chemical Properties

Molecular Structure:

Molecular Formula: C₄H₄O
Molecular Weight: 68.074
IUPAC Name: Furan
Synonyms of Furan (CAS NO.110-00-9): 1,4-Epoxy-1,3-butadiene ; 5-17-01-00291 (Beilstein Handbook Reference) ; AI3-24244 ; Axole ; BRN 0103221 ; CCRIS 3159 ; Divinylene oxide ; EINECS 203-727-3 ; Furfuran ; HSDB 89 ; NCI-C56202 ; Oxacyclopentadiene ; Oxole ; RCRA waste number U124 ; Tetrole ; Furan [UN2389] [Flammable liquid] ; UN2389
CAS NO: 110-00-9
Classification Code: Mutation data ; Reproductive Effect ; Tumor data
Melting point: -85.6 °C
Index of Refraction: 1.427
Molar Refractivity: 18.55 cm³
Molar Volume: 72.2 cm³
Surface Tension: 24.8 dyne/cm
Density: 0.942 g/cm³
Enthalpy of Vaporization: 27.1 kJ/mol
Boiling Point: 31.4 °C at 760 mmHg
Vapour Pressure: 605 mmHg at 25°C
Furan is aromatic because one of the lone pairs of electrons on the oxygen atom is delocalized into the ring, creating a 4n+2 aromatic system similar to benzene. Because of the aromaticity, the molecule is flat and lacks discrete double bonds. The other lone pair of electrons of the oxygen atom extends in the plane of the flat ring system. The sp2 hybridization is to allow one of the lone pairs of oxygen to reside in a p orbital and thus allow it to interact within the pi-system.

Furan History

In 1780 by Carl Wilhelm Scheele, the first Furan (CAS NO.110-00-9) derivative to be described was 2-furoic acid. Another important derivative, furfural, was reported by Johann Wolfgang Döbereiner in 1831 and characterised nine years later by John Stenhouse. Furan itself was first prepared by Heinrich Limpricht in 1870, although he called it tetraphenol.

Furan Uses

Furan (CAS NO.110-00-9) is mainly used to produce large quantities of hot-box process core Binder.

Furan Production

Furan can be obtained from FURFURAL by oxidation and decarboxylation of the resulting furan-2-carboxylic acid, the FURFURAL being derived by destructive distillation of corn cobs in the presence of SULFURIC ACID.
the Feist-Benary synthesis is the organic synthesis of classic furan.
and there is a simple synthesis methods for furans is the reaction of 1,4-diketones with PHOSPHORUS PENTOXIDE in the Paal-Knorr Synthesis. It is interesting that the Thiophene formation reaction of 1,4-diketones with Lawesson's reagent also forms furans as side products.

Furan Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	140mg/kg (140mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: HEMORRHAGE	Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926.
dog	LDLo	oral	234mg/kg (234mg/kg)	GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: HEMORRHAGE	Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926.
mouse	LC50	inhalation	120mg/m3/1H (120mg/m3)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979.
mouse	LD50	intraperitoneal	7mg/kg (7mg/kg)		American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979.
rabbit	LDLo	oral	234mg/kg (234mg/kg)	GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: HEMORRHAGE	Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926.
rat	LC50	inhalation	3398ppm/1H (3398ppm)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Hazelton Laboratories, Reports. Vol. HLA468-102, Pg. 1987,
rat	LD50	intraperitoneal	5200ug/kg (5.2mg/kg)		American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979.

Furan Safety Profile

Hazard Codes of Furan (CAS NO.110-00-9): Toxic T, Highly F+
Risk Statements: 45-12-19-20/22-38-48/22-52/53-68
R45: May cause cancer.
R12: Extremely flammable.
R19: May form explosive peroxides.
R20/22: Harmful by inhalation and if swallowed.
R38: Irritating to skin.
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed.
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R68: Possible risk of irreversible effects.
Safety Statements: 53-45-61
S53: Avoid exposure - obtain special instructions before use.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: OB3870000
F: 8-9-23
HazardClass: 3
PackingGroup: I

Furan Specification

Behavior of Furan (CAS NO.110-00-9) is quite dissimilar to that of the more typical heterocyclic ethers such as tetrahydrofuran due to its aromaticity, .It is considerably more reactive than benzene in electrophilic substitution reactions, due to the electron-donating effects of the oxygen heteroatom. Examination of the resonance contributors shows the increased electron density of the ring, leading to increased rates of electrophilic substitution.

Product Name

Furan

Synthetic route

Furan Chemical Properties

Furan History

Furan Uses

Furan Production

Furan Toxicity Data With Reference

Furan Safety Profile

Furan Specification

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