KDMF USDMF EDMF are all available! Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for t
Cas:100286-90-6
Min.Order:1 Kilogram
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:100286-90-6
Min.Order:1 Gram
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inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:100286-90-6
Min.Order:1 Kilogram
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inquiryQuickDetails CASNo.: 136572-09-3 OtherNames: … Appearance:White fine powder Storage:Preserve in tightly sealed,light and oxygen resistant containers Package:Drum and foil bag,or required by clients Application:For supplements and pharmaceut
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:100286-90-6
Min.Order:1 Gram
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Type:Manufacturers
inquiryUnique advantages for Irinotecan hydrochloride Cas 100286-90-6 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Yellowish or yellow crystalline powder Storage:Refrigerator Pac
Cas:100286-90-6
Min.Order:10 Gram
FOB Price: $43.0 / 45.0
Type:Trading Company
inquiryGood products, good service. We have professional sales team working on sales service for 15 years. Good products can win good market but can not stand long without good service. We have strict sales regulation and service procedure to make sure yo
Cas:100286-90-6
Min.Order:1 Metric Ton
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Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:100286-90-6
Min.Order:1 Gram
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Type:Manufacturers
inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:100286-90-6
Min.Order:1 Kilogram
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Type:Manufacturers
inquiryName:Irinotecan HCL CAS NO:100286-90-6 Grade:Medical scientific research and export Molecular formula:C33H39ClN4O6 Molecular weight:623.139 Product Quality 12 years of chemical raw materials Mature operation of the industry System stabilit
Cas:100286-90-6
Min.Order:25 Kilogram
FOB Price: $2.0 / 3.0
Type:Other
inquiryProduct Name: Irinotecan hydrochloride Synonyms: Camptothecin II;CPT-II;[1,4′-Bipiperidine]-1′-carboxylic acid, CPT-11,(S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,
Cas:100286-90-6
Min.Order:1 Gram
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:100286-90-6
Min.Order:1 Kilogram
FOB Price: $50.0 / 80.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:100286-90-6
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:100286-90-6
Min.Order:10 Kilogram
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Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:100286-90-6
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inquiryOur Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua
Cas:100286-90-6
Min.Order:10 Gram
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Type:Other
inquiryHanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
Cas:100286-90-6
Min.Order:1 Kilogram
FOB Price: $200.0 / 400.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:100286-90-6
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:100286-90-6
Min.Order:10 Gram
FOB Price: $3.5
Type:Trading Company
inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
Cas:100286-90-6
Min.Order:1 Gram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryIrinotecan hydrochloride CAS:100286-90-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:100286-90-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:100286-90-6
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) reasonable &
Cas:100286-90-6
Min.Order:10 Gram
Negotiable
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Hangzhou ZeErRui Chemical Co., Ltd. is a leading company that is focused on developing and producing high-quality flavor ingredients used for foods, pharmaceutic, cosmetics, and daily-use goods. Our goal is to produce flavor ingredients through scien
Cas:100286-90-6
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:100286-90-6
Min.Order:0 Metric Ton
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Type:Lab/Research institutions
inquiryHubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:100286-90-6
Min.Order:1 Kilogram
FOB Price: $3.0 / 5.0
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:100286-90-6
Min.Order:0
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Type:Lab/Research institutions
inquiry1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Binbo is engaged in R&D with perfect eq
Cas:100286-90-6
Min.Order:1 Kilogram
FOB Price: $0.1 / 0.2
Type:Lab/Research institutions
inquiryirinotecan
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With hydrogenchloride In dichloromethane; water at 0℃; for 2 - 3h; Product distribution / selectivity; | 100% |
With hydrogenchloride In tetrahydrofuran; water Product distribution / selectivity; | 100% |
With hydrogenchloride In water Product distribution / selectivity; | 95% |
4-piperidinopiperidin
7-ethyl-10-hydroxycamptothecin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Stage #1: 4-piperidinopiperidine-1-carbonyl chloride hydrochloride; 7-ethyl-10-hydroxycamptothecin With triethylamine In pyridine; dichloromethane at 30 - 40℃; for 1.5h; Stage #2: 4-piperidinopiperidin In pyridine; dichloromethane for 0.5h; | 90% |
7-ethyl-10-hydroxycamptothecin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Stage #1: 4-piperidinopiperidine-1-carbonyl chloride hydrochloride; 7-ethyl-10-hydroxycamptothecin With pyridine; triethylamine In dichloromethane at 30 - 40℃; for 1.5h; Stage #2: With 4-piperidinopiperidin In dichloromethane at 0 - 80℃; for 0.5h; pH=4.0; Stage #3: With hydrogenchloride In water; acetonitrile at 20℃; for 20h; Product distribution / selectivity; | 90% |
Stage #1: 4-piperidinopiperidine-1-carbonyl chloride hydrochloride; 7-ethyl-10-hydroxycamptothecin With pyridine; triethylamine In dichloromethane at 20℃; for 2h; Stage #2: With hydrogenchloride In water at 0 - 80℃; for 20h; pH=4.0; Product distribution / selectivity; | 80% |
With triethylamine In pyridine; dichloromethane; water at 20℃; for 2h; | 80% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With Britton-Robinson's buffer pH 6.0; water at 37℃; Equilibrium constant; Kinetics; Thermodynamic data; Ea, A, var. pH, var. temp., var. time; |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With hydrogenchloride In ethanol; n-heptane; water at 0 - 10℃; for 1h; pH=< 4; | |
With hydrogenchloride In ethanol; water; ethyl acetate at 0 - 10℃; for 1h; pH=< 4; | |
With hydrogenchloride In ethanol; water; ethyl acetate at 0 - 10℃; for 1h; pH=< 4; | |
With hydrogenchloride In methanol; water; ethyl acetate at 0 - 10℃; for 1h; pH=< 4; | |
With hydrogenchloride In methanol at 50℃; |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With hydrogenchloride In methanol; water at 50℃; |
4-piperidinopiperidin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: dichloromethane; acetonitrile / 20 - 70 °C 1.2: 20 °C 2.1: triethylamine; pyridine; acetamide / dichloromethane / 2 h / 30 - 40 °C / Inert atmosphere 3.1: hydrogenchloride / water View Scheme | |
Multi-step reaction with 3 steps 1.1: dichloromethane; hexane; acetonitrile / 20 - 25 °C 1.2: 20 °C 2.1: pyridine / dichloromethane; acetamide / 2 h / 30 - 40 °C / Inert atmosphere 3.1: hydrogenchloride / water / 20 h / 2 - 70 °C View Scheme | |
Multi-step reaction with 3 steps 1: dichloromethane / 0 - 20 °C 2: 1-Methylpyrrolidine / dichloromethane / 20 - 45 °C 3: hydrogenchloride / water / 3 h / 70 °C View Scheme | |
Multi-step reaction with 3 steps 1: N,N-dimethyl-formamide / 3 h / 60 - 65 °C 2: dichloromethane / 6 h / 45 - 50 °C 3: hydrogenchloride / water / 12 h / 20 °C View Scheme |
7-ethyl-10-hydroxycamptothecin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine; pyridine; acetamide / dichloromethane / 2 h / 30 - 40 °C / Inert atmosphere 2: hydrogenchloride / water View Scheme | |
Multi-step reaction with 2 steps 1: pyridine / dichloromethane; acetamide / 2 h / 30 - 40 °C / Inert atmosphere 2: hydrogenchloride / water / 20 h / 2 - 70 °C View Scheme |
4-piperidinopiperidine-1-carbonyl chloride
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine; pyridine; acetamide / dichloromethane / 2 h / 30 - 40 °C / Inert atmosphere 2: hydrogenchloride / water View Scheme | |
Multi-step reaction with 2 steps 1: pyridine / dichloromethane; acetamide / 2 h / 30 - 40 °C / Inert atmosphere 2: hydrogenchloride / water / 20 h / 2 - 70 °C View Scheme |
(4S)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: trifluoroacetic acid / toluene / 20 h / 85 - 90 °C / Industry scale 2: 1-Methylpyrrolidine / dichloromethane / 20 - 45 °C 3: hydrogenchloride / water / 3 h / 70 °C View Scheme |
2'-amino-5'-hydroxypropiophenone
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: trifluoroacetic acid / toluene / 20 h / 85 - 90 °C / Industry scale 2: 1-Methylpyrrolidine / dichloromethane / 20 - 45 °C 3: hydrogenchloride / water / 3 h / 70 °C View Scheme | |
Multi-step reaction with 3 steps 1: trifluoroacetic acid / toluene / 6 h / 80 °C 2: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 3: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: toluene-4-sulfonic acid / toluene / 5 h / Reflux 2.1: lithium hydroxide / methanol; water / 1 h / 25 - 30 °C 2.2: 18 - 22 °C 3.1: sulfuric acid / 2 h / 0 - 5 °C 4.1: triethylamine; pyridine / dichloromethane / 20 - 40 °C 4.2: pH 2-3 View Scheme |
1-(5-fluoro-2-nitrophenyl)propan-1-one
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: sodium hydroxide / 2 h / 0 - 20 °C 2: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux 3: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 4: trifluoroacetic acid / toluene / 6 h / 80 °C 5: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 6: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux 2: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 3: trifluoroacetic acid / toluene / 6 h / 80 °C 4: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 5: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
1-(5-hydroxy-2-nitrophenyl)propan-1-one
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 2: trifluoroacetic acid / toluene / 6 h / 80 °C 3: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 4: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
3-Fluorobenzaldehyde
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1.1: hydroxylamine hydrochloride; sodium hydroxide; water / ethanol / 4 h / 5 °C 2.1: acetic anhydride / 2 h / 110 °C 3.1: magnesium / tetrahydrofuran / 0.5 h / 40 °C 3.2: 1 h / 40 °C 4.1: nitric acid / dichloromethane / 12 h / 10 - 20 °C 5.1: sodium hydroxide / 2 h / 0 - 20 °C 6.1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux 7.1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 8.1: trifluoroacetic acid / toluene / 6 h / 80 °C 9.1: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 10.1: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
3-fluorobenzaldehyde oxime
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1.1: acetic anhydride / 2 h / 110 °C 2.1: magnesium / tetrahydrofuran / 0.5 h / 40 °C 2.2: 1 h / 40 °C 3.1: nitric acid / dichloromethane / 12 h / 10 - 20 °C 4.1: sodium hydroxide / 2 h / 0 - 20 °C 5.1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux 6.1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 7.1: trifluoroacetic acid / toluene / 6 h / 80 °C 8.1: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 9.1: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
m-Fluorobenzonitrile
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: magnesium / tetrahydrofuran / 0.5 h / 40 °C 1.2: 1 h / 40 °C 2.1: nitric acid / dichloromethane / 12 h / 10 - 20 °C 3.1: sodium hydroxide / 2 h / 0 - 20 °C 4.1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux 5.1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 6.1: trifluoroacetic acid / toluene / 6 h / 80 °C 7.1: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 8.1: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
1-(3-fluorophenyl)propan-1-one
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: nitric acid / dichloromethane / 12 h / 10 - 20 °C 2: sodium hydroxide / 2 h / 0 - 20 °C 3: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux 4: sodium carbonate; sodium dithionite; water / 1 h / 20 °C 5: trifluoroacetic acid / toluene / 6 h / 80 °C 6: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere 7: hydrogenchloride; water / 3 h / 20 - 70 °C View Scheme |
4-piperidinopiperidine-1-carbonyl chloride
7-ethyl-10-hydroxycamptothecin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Stage #1: 4-piperidinopiperidine-1-carbonyl chloride; 7-ethyl-10-hydroxycamptothecin With dmap; triethylamine In dichloromethane at 20℃; Stage #2: With hydrogenchloride In methanol pH=1 - 2; Reagent/catalyst; | 14.1 g |
4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: toluene-4-sulfonic acid / toluene / 5 h / Reflux 2.1: lithium hydroxide / methanol; water / 1 h / 25 - 30 °C 2.2: 18 - 22 °C 3.1: sulfuric acid / 2 h / 0 - 5 °C 4.1: triethylamine; pyridine / dichloromethane / 20 - 40 °C 4.2: pH 2-3 View Scheme |
4,11-diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14 (4H,12H)-dione
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: lithium hydroxide / methanol; water / 1 h / 25 - 30 °C 1.2: 18 - 22 °C 2.1: sulfuric acid / 2 h / 0 - 5 °C 3.1: triethylamine; pyridine / dichloromethane / 20 - 40 °C 3.2: pH 2-3 View Scheme |
camptothecin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: ferrous(II) sulfate heptahydrate; sulfuric acid; acetic acid / water / 5 °C 1.2: 0.25 h / 5 °C 2.1: acetic acid; dihydrogen peroxide / 8 h / 80 °C 3.1: sulfuric acid; water / 1,4-dioxane; acetonitrile / Inert atmosphere; Irradiation 4.1: dichloromethane / 6 h / 45 - 50 °C 5.1: hydrogenchloride / water / 12 h / 20 °C View Scheme |
7-ethylcamptothecin
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: acetic acid; dihydrogen peroxide / 8 h / 80 °C 2: sulfuric acid; water / 1,4-dioxane; acetonitrile / Inert atmosphere; Irradiation 3: dichloromethane / 6 h / 45 - 50 °C 4: hydrogenchloride / water / 12 h / 20 °C View Scheme |
7-Ethylcamptothecin 1-Oxide
irinotecan hydrochloirde
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sulfuric acid; water / 1,4-dioxane; acetonitrile / Inert atmosphere; Irradiation 2: dichloromethane / 6 h / 45 - 50 °C 3: hydrogenchloride / water / 12 h / 20 °C View Scheme |
N-(t-butoxycarbonyl)glycinal
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 17℃; Inert atmosphere; | 95% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane; acetonitrile at 0 - 20℃; Inert atmosphere; | 95% |
irinotecan hydrochloirde
14-azido-3,6,9,12-tetraoxa-1-tetradecanoic acid
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane Inert atmosphere; | 90% |
irinotecan hydrochloirde
irinotecan hydrochloride trihydrate
Conditions | Yield |
---|---|
With hydrogenchloride; water In ethanol at 75 - 80℃; | 87% |
With water In ethanol Heating / reflux; |
Conditions | Yield |
---|---|
With hydrogenchloride In water at 65℃; for 0.0833333h; | 84% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 77.1% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 76.7% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 74.3% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 73.7% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 73.5% |
Conditions | Yield |
---|---|
Stage #1: irinotecan hydrochloirde With dmap In dichloromethane for 0.166667h; Stage #2: 1,4-oxathiane-2,6-dione With dmap In dichloromethane at 20℃; for 19h; | 73% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 72.8% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 71% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 70.5% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 69.5% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 69% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 67.6% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 67.2% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane; acetonitrile at 20℃; | 67% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 66.7% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 65.7% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 65.7% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 63.8% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 60.5% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 60.3% |
irinotecan hydrochloirde
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 57.8% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 30℃; | 57.4% |
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