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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Propanone,1-cyclohexyl-

Cas:103-78-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

CYCLOHEXYLACETONE cas no: 103-78-6

Cas:103-78-6

Min.Order:1 Gram

FOB Price: $10000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 103-78-6 with competitive price

Cas:103-78-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

103-78-6 CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Propanone,1-cyclohexyl- 103-78-6

Cas:103-78-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

best price,best quality and fast delivery assurance available in sample product and customization with years of export experience along with excellent quality, advanced services and competitive prices the quality of products conform u

CYCLOHEXYLACETONE CAS NO.103-78-6

Cas:103-78-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Propanone,1-cyclohexyl-

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Cyclohexylacetone

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply cyclohexylacetone

Cas:103-78-6

Min.Order:0

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Propanone,1-cyclohexyl-

Cas:103-78-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Cyclohexylacetone

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

cyclohexylacetone

Cas:103-78-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

1-cyclohexylacetone

Cas:103-78-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

factory?direct?sale Application:healing drugs

2-Propanone,1-cyclohexyl-

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

2-Propanone,1-cyclohexyl- cas 103-78-6Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-Propanone,1-cyclohexyl- cas 103-78-6

Cas:103-78-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

2-Propanone,1-cyclohexyl-

Cas:103-78-6

Min.Order:0

Negotiable

Type:Other

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Cyclohexylacetone

Cas:103-78-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

103-78-6

Cas:103-78-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Yinghao Pharm Co.,Ltd.

Yinghao Pharm products include: leader molecule, heterocyclic compounds,chiral compounds, photoelectric materials, biochemical reagents etc. For example:benzene, pyrimidine, boricacid,pyridine, pyrazole, imidazole, pyrrole, fluorine and other derivat

CYCLOHEXYLACETONE

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

U-Chemo Holding Co.,Limited

U-CHEMO is a high-tech enterprise taking pharmaceutical intermediates and fine chemicals as main products. We pay high attention on product quality and apply quality management in the whole manufacturing process from research to production. In additi

1-Cyclohexylacetone

Cas:103-78-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane
104543-13-7

1-cyclohexyl-2-nitro-2(pyridine-2-thiyl)-propane

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With titanium(III) chloride In tetrahydrofuran; water Ambient temperature;100%
prop-2-ynylcyclohexane
17715-00-3

prop-2-ynylcyclohexane

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With hexafluoroantimonic acid; AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); water at 120℃; for 24h;94%
1-phenyl-acetone
103-79-7

1-phenyl-acetone

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With hydrogen In tetrahydrofuran at 24.84℃; under 30003 Torr; chemoselective reaction;92%
With hydrogen; K5PPdW11O39/C In various solvent(s) at 200℃; under 22502.3 Torr; for 4h;100 % Chromat.
2-((E)-2-Cyclohexyl-1-methyl-vinyl)-[1,3,2]dioxaborinane
105763-14-2

2-((E)-2-Cyclohexyl-1-methyl-vinyl)-[1,3,2]dioxaborinane

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide In tetrahydrofuran for 2h; Ambient temperature;86%
allylcyclohexane
2114-42-3

allylcyclohexane

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With tetrakis(acetonitrile)palladium(II) tetrafluoroborate; [bis(acetoxy)iodo]benzene; water; nitrobenzene; p-benzoquinone In dimethyl sulfoxide at 35℃; for 48h; Wacker Oxidation; Sealed tube; Darkness;85%
With oxygen; copper(l) chloride; palladium dichloride In water; N,N-dimethyl-formamide at 55℃; under 760.051 Torr; for 24h; Wacker Oxidation; regioselective reaction;68%
Cyclohexylacetic acid
5292-21-7

Cyclohexylacetic acid

methyllithium
917-54-4

methyllithium

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
Stage #1: methyllithium With copper(l) cyanide In diethyl ether at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: Cyclohexylacetic acid In diethyl ether at 0 - 20℃; for 15h; Inert atmosphere;
81%
In diethyl ether
cyclohexane
110-82-7

cyclohexane

percarbonate de O,O-tert-butyle et O-isopropyle
65700-06-3

percarbonate de O,O-tert-butyle et O-isopropyle

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With tert-butyl peroxyacetate at 95℃; for 16h;72%
allylcyclohexane
2114-42-3

allylcyclohexane

A

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

B

3-cyclohexylpropanal
4361-28-8

3-cyclohexylpropanal

Conditions
ConditionsYield
With bis(benzonitrile)palladium(II) dichloride; silver(I) nitrite; copper(II) choride dihydrate; nitromethane; oxygen; tert-butyl alcohol at 20℃; under 760.051 Torr; for 6h; Wacker Oxidation; Overall yield = 75 %;A n/a
B 60%
With ethanol; iodine; mercury(II) oxide Erwaermen mit alkoh. Kalilauge und verd. Schwefelsaeure;
With diethyl ether; iodine; mercury(II) oxide Behandeln mit Silbernitrat in Aether;
With methanol; iodine; mercury(II) oxide Erwaermen mit alkoh. Kalilauge und verd. Schwefelsaeure;
acetone
67-64-1

acetone

cyclohexene
110-83-8

cyclohexene

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With potassium permanganate; potassium acetate; manganese(II) acetate; acetic acid at 70℃; addition of KMnO4, 4-10 h;56%
With sodium persulfate; silver nitrate In water for 8h; Heating;40%
In water at 40℃; for 6h; Photoirradiation; Inert atmosphere;43 %Chromat.
With potassium acetate; manganese(II) acetate; acetic anhydride; lead dioxide; acetic acid at 70℃; for 6h;5.9 g
cyclohexane
110-82-7

cyclohexane

percarbonate de O,O-tert-butyle et O-isopropyle
65700-06-3

percarbonate de O,O-tert-butyle et O-isopropyle

A

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

B

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

C

2,5-hexanedione
110-13-4

2,5-hexanedione

Conditions
ConditionsYield
at 130℃; for 2.5h;A 55%
B n/a
C n/a
cyclohexane
110-82-7

cyclohexane

percarbonate de O,O-tert-butyle et O-isopropyle
65700-06-3

percarbonate de O,O-tert-butyle et O-isopropyle

A

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

B

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

C

2,5-hexanedione
110-13-4

2,5-hexanedione

D

tert-butyl alcohol
75-65-0

tert-butyl alcohol

Conditions
ConditionsYield
at 130℃; for 2.5h; Further byproducts given;A 55%
B n/a
C n/a
D n/a
1-(1-phenylethyl)-2-methyleneaziridine

1-(1-phenylethyl)-2-methyleneaziridine

c-C6H11MgX

c-C6H11MgX

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
Stage #1: N-(1-Phenylethyl)-2-methyleneaziridine; c-C6H11MgX With copper(l) iodide; boron trifluoride diethyl etherate In tetrahydrofuran at -30 - 0℃; Ring cleavage;
Stage #2: In tetrahydrofuran Hydrolysis; Further stages.;
50%
cyclohexylmagnesiumchloride
931-51-1

cyclohexylmagnesiumchloride

1-(1-phenylethyl)-2-methyleneaziridine

1-(1-phenylethyl)-2-methyleneaziridine

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With copper(l) iodide; boron trifluoride diethyl etherate In tetrahydrofuran at -30 - 0℃; for 1h;49%
3-cyclohexyl-2-methyl-1-nitro-2-propanol

3-cyclohexyl-2-methyl-1-nitro-2-propanol

A

(R)-3-cyclohexyl-2-methyl-1-nitro-2-propanol

(R)-3-cyclohexyl-2-methyl-1-nitro-2-propanol

B

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With (S)-La-Li3-(binaphthoxide)3; C42H36LaLi3O12 In tetrahydrofuran at -20℃; for 15h; Retro-nitroaldol reaction; optical yield given as %ee; enantioselective reaction;A 40%
B n/a
cyclohexylallene
5664-17-5

cyclohexylallene

A

(E)-1,6-Dicyclohexyl-hex-5-en-2-one

(E)-1,6-Dicyclohexyl-hex-5-en-2-one

B

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With carbon monoxide; trifluoroacetic acid; dodecacarbonyl-triangulo-triruthenium In water; isopropyl alcohol at 120℃; under 760 Torr; for 12h;A 17%
B 8%
1-cyclohexenylacetone
768-50-3

1-cyclohexenylacetone

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With hydrogen; palladium
1-iodocyclohexane
626-62-0

1-iodocyclohexane

sodium ethyl acetylacetate enolate
1007476-32-5

sodium ethyl acetylacetate enolate

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With ethanol
1-iodocyclohexane
626-62-0

1-iodocyclohexane

sodium ethyl acetylacetate enolate
1007476-32-5

sodium ethyl acetylacetate enolate

A

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

B

ethyl 2-cyclohexylacetoacetate
10547-56-5

ethyl 2-cyclohexylacetoacetate

C

cyclohexene
110-83-8

cyclohexene

2-cyclohexylacetonitrile
4435-14-7

2-cyclohexylacetonitrile

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With methyl magnesium iodide
1-cyclohexyl-2-propanol
76019-86-8

1-cyclohexyl-2-propanol

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With chromic acid
cyclohexanone
108-94-1

cyclohexanone

isopropyl alcohol
67-63-0

isopropyl alcohol

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With aluminium oxide-zinc oxide-copper (II)-oxide contact at 350℃; under 15445.7 Torr;
methyl magnesium iodide
917-64-6

methyl magnesium iodide

cyclohexylacetic acid chloride
23860-35-7

cyclohexylacetic acid chloride

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
at -10℃;
ethyl 2-cyclohexylacetoacetate
10547-56-5

ethyl 2-cyclohexylacetoacetate

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
at 525℃;
3-bromo-2-methoxypropene
26562-24-3

3-bromo-2-methoxypropene

1-iodocyclohexane
626-62-0

1-iodocyclohexane

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
(i) Ni(CO)4, (ii) /BRN= 1900797/; Multistep reaction;
1-cyclohexylpropyne
18736-95-3

1-cyclohexylpropyne

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
(i) dicyclohexylborane, THF, (ii) aq. H2O2, aq. NaOH; Multistep reaction;
2-chloro-3-cyclohexylprop-1-ene
67894-88-6

2-chloro-3-cyclohexylprop-1-ene

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
With mercury(II) diacetate In trifluoroacetic acid
chloroacetone
78-95-5

chloroacetone

cyclohexene
110-83-8

cyclohexene

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
Irradiation;
((Z)-2-Bromo-1-methyl-vinyloxy)-trimethyl-silane
61668-34-6

((Z)-2-Bromo-1-methyl-vinyloxy)-trimethyl-silane

cyclohexylmagnesium bromide
931-50-0

cyclohexylmagnesium bromide

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

Conditions
ConditionsYield
(i) Ni catalyst, (ii) aq. HCl; Multistep reaction;
cyclohexane
110-82-7

cyclohexane

percarbonate de O,O-tert-butyle et O-isopropyle
65700-06-3

percarbonate de O,O-tert-butyle et O-isopropyle

A

4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

B

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

C

2,5-hexanedione
110-13-4

2,5-hexanedione

D

acetone
67-64-1

acetone

E

tert-butyl alcohol
75-65-0

tert-butyl alcohol

Conditions
ConditionsYield
at 130℃; for 2.5h; Product distribution; Mechanism; variation of time and temperature;
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

1-bromo-3-cyclohexyl-2-propanone
152757-52-3

1-bromo-3-cyclohexyl-2-propanone

Conditions
ConditionsYield
With bromine In methanol at 15℃;98%
With water; bromine In methanol at 15 - 20℃;78%
With bromine In methanol at 15℃; Cooling with ice;
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

1-cyclohexyl-2-propanol
76019-86-8

1-cyclohexyl-2-propanol

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one With n-butyllithium; 1-(2-hydroxyethyl)-3-methyl-1H-imidazol-3-ium trifluoromethanesulfonate; iron(II) acetate In tetrahydrofuran at 65℃; for 3h; Inert atmosphere;
Stage #2: With water; sodium hydroxide In tetrahydrofuran; methanol at 20℃; for 2h; Inert atmosphere;
85%
With methanol; sodium tetrahydroborate at 0 - 20℃; for 2.25h;79%
Stage #1: 4-cyclohexyl-butan-2-one With n-butyllithium; iron(II) acetate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride In tetrahydrofuran; hexane at 65℃; Inert atmosphere;
Stage #2: With sodium hydroxide In tetrahydrofuran; methanol; hexane; water at 20℃; for 3h; Inert atmosphere;
66%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With aluminum (III) chloride; sodium nitrite In N,N-dimethyl-formamide at 100℃; for 5h; Schlenk technique;77%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

C14H26Si
1266614-73-6

C14H26Si

Conditions
ConditionsYield
Stage #1: diazomethyl-trimethyl-silane With n-butyllithium In tetrahydrofuran; diethyl ether; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: 4-cyclohexyl-butan-2-one In tetrahydrofuran; diethyl ether; hexane at -78 - 20℃; for 4h; Inert atmosphere; regioselective reaction;
61%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

ethyl α,γ-dioxo-cyclohexanepentanoate
1561966-01-5

ethyl α,γ-dioxo-cyclohexanepentanoate

Conditions
ConditionsYield
With sodium hydride In ethanol at 20℃; for 5.25h; Cooling with ice;59%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

4-Cyclohexylacetessigsaeure-ethylester
64127-44-2

4-Cyclohexylacetessigsaeure-ethylester

Conditions
ConditionsYield
With sodium ethanolate In ethanol at 0 - 20℃; Inert atmosphere;57%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

diethyl 2-acetamido-2-(2-(aminomethyl)benzyl)malonate

diethyl 2-acetamido-2-(2-(aminomethyl)benzyl)malonate

diethyl 2-acetamido-2-(2-(((1-cyclohexylpropan-2-yl)amino)methyl)benzyl)malonate

diethyl 2-acetamido-2-(2-(((1-cyclohexylpropan-2-yl)amino)methyl)benzyl)malonate

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; diethyl 2-acetamido-2-(2-(aminomethyl)benzyl)malonate In methanol at 100℃; for 2h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 6h;
57%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

(2-(cyclohexyloxy)phenyl)methanamine

(2-(cyclohexyloxy)phenyl)methanamine

1-cyclohexyl-N-(2-(cyclohexyloxy)benzyl)propan-2-amine

1-cyclohexyl-N-(2-(cyclohexyloxy)benzyl)propan-2-amine

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; (2-(cyclohexyloxy)phenyl)methanamine In methanol at 100℃; for 2h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 6h;
51%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

(2-(aminomethyl)phenyl)methanesulfonamide

(2-(aminomethyl)phenyl)methanesulfonamide

(2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)methanesulfonamide

(2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)methanesulfonamide

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; (2-(aminomethyl)phenyl)methanesulfonamide In methanol at 100℃; for 2h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 6h;
51%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

(2-((methylsulfonyl)methyl)phenyl)methanamine

(2-((methylsulfonyl)methyl)phenyl)methanamine

1-cyclohexyl-N-(2-((methylsulfonyl)methyl)benzyl)propan-2-amine

1-cyclohexyl-N-(2-((methylsulfonyl)methyl)benzyl)propan-2-amine

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; (2-((methylsulfonyl)methyl)phenyl)methanamine In methanol at 100℃; for 2h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 6h;
49%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

methyl (1r,3r)-3-(((2-(aminomethyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

methyl (1r,3r)-3-(((2-(aminomethyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

methyl (1r,3r)-3-(((2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

methyl (1r,3r)-3-(((2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; methyl (1r,3r)-3-(((2-(aminomethyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate In methanol at 100℃; for 3h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 7h;
44%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

(2-((3-methoxybenzyl)oxy)phenyl)methanamine

(2-((3-methoxybenzyl)oxy)phenyl)methanamine

1-cyclohexyl-N-(2-((3-methoxybenzyl)oxy)benzyl)propan-2-amine

1-cyclohexyl-N-(2-((3-methoxybenzyl)oxy)benzyl)propan-2-amine

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; (2-((3-methoxybenzyl)oxy)phenyl)methanamine In methanol at 100℃; for 2h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 6h;
44%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

1-(2-(aminomethyl)phenyl)-N-(1-methylpiperidin-4-yl)methanesulfonamide

1-(2-(aminomethyl)phenyl)-N-(1-methylpiperidin-4-yl)methanesulfonamide

1-(2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)-N-(1-methylpiperidin-4-yl)methanesulfonamide

1-(2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)-N-(1-methylpiperidin-4-yl)methanesulfonamide

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; 1-(2-(aminomethyl)phenyl)-N-(1-methylpiperidin-4-yl)methanesulfonamide In methanol at 100℃; for 3h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 7h;
42%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

(2-((3-methylcyclohexyl)oxy)phenyl)methanamine

(2-((3-methylcyclohexyl)oxy)phenyl)methanamine

1-cyclohexyl-N-(2-((3-methylcyclohexyl)oxy)benzyl)propan-2-amine

1-cyclohexyl-N-(2-((3-methylcyclohexyl)oxy)benzyl)propan-2-amine

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; (2-((3-methylcyclohexyl)oxy)phenyl)methanamine In methanol at 100℃; for 2h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 6h;
41%
4-cyclohexyl-butan-2-one
103-78-6

4-cyclohexyl-butan-2-one

methyl (1s,3s)-3-(((2-(aminomethyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

methyl (1s,3s)-3-(((2-(aminomethyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

methyl (1s,3s)-3-(((2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

methyl (1s,3s)-3-(((2-(((1-cyclohexylpropan-2-yl)amino)methyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate

Conditions
ConditionsYield
Stage #1: 4-cyclohexyl-butan-2-one; methyl (1s,3s)-3-(((2-(aminomethyl)phenyl)methyl)sulfonamido)cyclobutane-1-carboxylate In methanol at 100℃; for 3h;
Stage #2: With methanol; sodium tetrahydroborate at 60℃; for 7h;
41%

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