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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Cyclohexanecarbonitrile Manufacturer/High quality/Best price/In stock

Cas:766-05-2

Min.Order:1 Kilogram

FOB Price: $3.0

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Cyclohexanecarbonitrile supplier in China

Cas:766-05-2

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Cyclohexanecarbonitrile Manufacturer/High quality/Best price/In stock CAS NO.766-05-2

Cas:766-05-2

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 766-05-2 Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Gram

FOB Price: $0.1

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cyanocyclohexane

Cas:766-05-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 766-05-2 with best quality

Cas:766-05-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 766-05-2 Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:10 Kilogram

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Henan Sinotech Import&Export Corporation

CAS:766-05-2 Structure: Assay: >99% Molecular formula: C7H11N Molecular weight: 109.17 Synonym:Cyanocycloh

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:5 Metric Ton

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Cyclohexanecarbonitrile 766-05-2

Cas:766-05-2

Min.Order:1 Kilogram

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Qingdao Beluga Import and Export Co., LTD

Cyclohexanecarbonitrile CAS:766-05-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

Cyclohexanecarbonitrile CAS:766-05-2

Cas:766-05-2

Min.Order:1 Gram

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Kilogram

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Cyclohexanecarbonitrile

Cas:766-05-2

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Ethyl nipecotate

Cas:766-05-2

Min.Order:4 Kilogram

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Gram

FOB Price: $1.0

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:10 Gram

FOB Price: $100.0

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

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HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Used as Pharmaceutical Intermediates Transp

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Kilogram

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

cyclohexanecarbonitrile low price

Cas:766-05-2

Min.Order:1 Gram

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Siwei Development Group Ltd.

Product name: Cyclohexanecarbonitrile CAS No.:766-05-2 Molecule Formula:C7H11N Molecule Weight:109.16 Purity: 99% Package: 200kg/drum Description:Light yellow transparent liquid Manufacture Standards:Enterprise Standard TESTING I

High Quality Cyclohexanecarbonitrile in stock

Cas:766-05-2

Min.Order:1 Kilogram

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

CyclohexanecarbonitrileCAS NO.: 766-05-2

Cas:766-05-2

Min.Order:1 Gram

FOB Price: $2.0

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferCyclohexanecarbonitrile

Cas:766-05-2

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Shanghai Minstar Chemical Co., Ltd

Melting point 11 °C (lit.) Boiling point 75-76 °C/16 mmHg (lit.) density 0.919 g/mL at 25 °C (lit.) refractive index n20/D 1.4505(lit.) Fp 149 °F storage temp. Store below +30°C. CAS DataBase Referen

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Metric Ton

FOB Price: $66.0

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Gram

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Metric Ton

FOB Price: $1.5

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:0

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Kilogram

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Type:Other

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:1 Metric Ton

FOB Price: $1.0

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Cas no.766-05-2 98% Cyclohexanecarbonitrile

Cas:766-05-2

Min.Order:0

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Synthetic route

cyclohexanecarbaldoxime
4715-11-1

cyclohexanecarbaldoxime

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With nickel(II) chloride dihydrate In acetonitrile at 80℃; Molecular sieve; Inert atmosphere;100%
With MIL-100 (Fe)-NH4F In o-xylene at 153 - 160℃; for 1h; Dean-Stark; Inert atmosphere;97%
With phosphoric acid diethyl ester 2-phenylbenzimidazol-1-yl ester; triethylamine In acetonitrile at 20℃; for 0.916667h;94%
N(C4H9)4(1+)*Cu(1+)*2CN(1-)=(N(C4H9)4)[Cu(CN)2]

N(C4H9)4(1+)*Cu(1+)*2CN(1-)=(N(C4H9)4)[Cu(CN)2]

cyclohexyl chloride
542-18-7

cyclohexyl chloride

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide In acetonitrile at 20℃; for 4h; Reagent/catalyst; Inert atmosphere; UV-irradiation;98%
cyclohexylmethylamine
3218-02-8

cyclohexylmethylamine

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With pyridine; Oxone; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; Pyridine hydrobromide In dichloromethane at 20℃; for 12h; Green chemistry;97%
With pyridine; 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate In dichloromethane at 20℃; for 12h; Inert atmosphere;95%
With water; potassium hydroxide at 25℃; pH=13.6; Electrochemical reaction;95%
cyclohexanylcarbonyl chloride
2719-27-9

cyclohexanylcarbonyl chloride

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With sulfonamide In sulfolane at 120℃; for 3h;95%
1-cyclohexanecarboxaldehyde N,N-dimethylhydrazone
19888-79-0

1-cyclohexanecarboxaldehyde N,N-dimethylhydrazone

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With pyridine; dihydrogen peroxide; acetic acid; methyltrioxorhenium(VII) In water; acetonitrile for 0.25h;95%
Multi-step reaction with 2 steps
1: benzene / 7 h / Heating
2: NaOMe / methanol / 4 h / Heating
View Scheme
cyclohexylmethyl alcohol
100-49-2

cyclohexylmethyl alcohol

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With ammonia at 210℃; Inert atmosphere;95%
With nitrogen; ammonia at 240℃; Heating;88%
With ammonium hydroxide; dihydrogen peroxide In water; acetonitrile at 50℃; for 8h;76%
cyclohexanecarbaldehyde
2043-61-0

cyclohexanecarbaldehyde

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With ammonia; iodine In tetrahydrofuran; water at 20℃; for 0.166667h;94%
Stage #1: cyclohexanecarbaldehyde With 3 A molecular sieve; hydroxylamine hydrochloride; 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 10h;
Stage #2: With ethyl phosphodichloridite In dichloromethane at 20℃; for 5h; Further stages.;
92%
With bismuth(lll) trifluoromethanesulfonate; acetylhydroxamic acid In acetonitrile for 24h; Reflux;88%
cyclohexylcarboxamide
1122-56-1

cyclohexylcarboxamide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With trichloromethyl chloroformate In various solvent(s) 0-5 deg C then heated to 60 deg C, 5 min;93%
With lead acetate In dichloromethane for 12h; Reflux;90%
With oxalyl dichloride; triethylamine In dimethyl sulfoxide; acetonitrile at 20℃; for 0.666667h; Swern Oxidation;87%
Dimethyl-dithiocarbamic acid 1-cyano-cyclohexyl ester
61540-43-0

Dimethyl-dithiocarbamic acid 1-cyano-cyclohexyl ester

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In benzene at 80℃; for 5h;93%
methanesulfonyl cyanide
24225-08-9

methanesulfonyl cyanide

Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester
105398-69-4

Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
In dichloromethane at 0℃; Irradiation;90%
N-cyanoimidazole
36289-36-8

N-cyanoimidazole

cyclohexylmagnesium bromide
931-50-0

cyclohexylmagnesium bromide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
In tetrahydrofuran at -78℃; for 0.5h; cyanation;90%
(E)-N-(cyclohexylmethylidene)hydroxylamine
30950-35-7

(E)-N-(cyclohexylmethylidene)hydroxylamine

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; 4 A molecular sieve In acetonitrile at 80℃; for 0.166667h;90%
Cyclohexanethiol
1569-69-3

Cyclohexanethiol

tetra-n-butylammonium cyanide
10442-39-4

tetra-n-butylammonium cyanide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile at 20℃; for 5h;90%
2-(cyclohexyloxy)tetrahydro-2H-pyran
709-83-1

2-(cyclohexyloxy)tetrahydro-2H-pyran

tetra-n-butylammonium cyanide
10442-39-4

tetra-n-butylammonium cyanide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile for 7h; Heating;90%
cyclohexane
110-82-7

cyclohexane

3-oxo-1λ3-benzo[d][1,2]iodaoxole-1(3H)-carbonitrile
172876-96-9

3-oxo-1λ3-benzo[d][1,2]iodaoxole-1(3H)-carbonitrile

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With tert-Butyl peroxybenzoate In ethyl acetate at 110℃; for 16h; Solvent; Temperature; Reagent/catalyst; Time; Sealed tube; Inert atmosphere; Glovebox;90%
P-toluenesulfonyl cyanide
19158-51-1

P-toluenesulfonyl cyanide

Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester
105398-69-4

Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
In dichloromethane at 0℃; Irradiation;88%
Cyclohexanecarboxylic acid
98-89-5

Cyclohexanecarboxylic acid

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With thionyl chloride; sulfonamide In sulfolane at 120℃; for 3h;88%
With sulfuric acid; acetonitrile at 95℃; for 4h;59%
Multi-step reaction with 2 steps
1.1: thionyl chloride / tetrahydrofuran / 1 h / 50 °C
1.2: 0.08 h / 0 °C
2.1: palladium diacetate; Selectfluor; acetonitrile / 18 h / 20 °C
View Scheme
With indium(III) chloride; acetonitrile at 200℃; under 11251.1 Torr; for 14h;86 %Chromat.
1-(1-Cyanocyclohexyl)-2-carbomethoxyhydrazine
61827-29-0

1-(1-Cyanocyclohexyl)-2-carbomethoxyhydrazine

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With sodium cyanide In methanol at 17℃; for 4.7h; electrolysis;86%
cyclohexylmethylamine
3218-02-8

cyclohexylmethylamine

A

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

B

cyclohexylcarboxamide
1122-56-1

cyclohexylcarboxamide

C

Cyclohexanecarboxylic acid
98-89-5

Cyclohexanecarboxylic acid

Conditions
ConditionsYield
With water; oxygen at 140℃; under 3800.26 Torr; for 24h;A n/a
B 86%
C n/a
trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

cyclohexanylcarbonyl chloride
2719-27-9

cyclohexanylcarbonyl chloride

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); triphenylphosphine In toluene at 110℃; for 1h; Schlenk technique; Inert atmosphere;86%
P-toluenesulfonyl cyanide
19158-51-1

P-toluenesulfonyl cyanide

cyclohexylzinc iodide
121883-35-0

cyclohexylzinc iodide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 25℃;84%
1-(1-Cyanocyclohexyl)-2-acetylhydrazine
27702-91-6

1-(1-Cyanocyclohexyl)-2-acetylhydrazine

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With sodium cyanide In methanol at 17℃; for 4.7h; electrolysis;83%
tetra-n-butylammonium cyanide
10442-39-4

tetra-n-butylammonium cyanide

cyclohexanol
108-93-0

cyclohexanol

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile at 20℃; for 0.166667h;83%
2-cyclohexyl-1,3-dioxolane
4362-48-5

2-cyclohexyl-1,3-dioxolane

A

cyclohexanecarbaldoxime
4715-11-1

cyclohexanecarbaldoxime

B

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With hydroxylamine hydrochloride; toluene-4-sulfonic acid In ethanol for 2h; Heating;A 8%
B 81%
Allyl 1-cyanocyclohexanecarboxylate
102804-62-6

Allyl 1-cyanocyclohexanecarboxylate

A

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

B

cyclohex-1-enecarbonitrile
1855-63-6

cyclohex-1-enecarbonitrile

Conditions
ConditionsYield
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine In various solvent(s) for 1h; Heating; Yields of byproduct given;A n/a
B 81%
pyridin-2-yl cyanate
175351-40-3

pyridin-2-yl cyanate

cyclohexylmagnesium bromide
931-50-0

cyclohexylmagnesium bromide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
In tetrahydrofuran at 0℃; for 0.166667h;80%
N'-[1-Cyclohexyl-meth-(Z)-ylidene]-N,N-dimethyl-hydrazine
10424-96-1

N'-[1-Cyclohexyl-meth-(Z)-ylidene]-N,N-dimethyl-hydrazine

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
With dihydrogen peroxide; sodium carbonate; acetonitrile at 55℃; for 18h;80%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

P-toluenesulfonyl cyanide
19158-51-1

P-toluenesulfonyl cyanide

(Prop-2-ene-1-sulfonyl)-cyclohexane

(Prop-2-ene-1-sulfonyl)-cyclohexane

A

methyl cyclohexylcarboxylate
4630-82-4

methyl cyclohexylcarboxylate

B

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Conditions
ConditionsYield
Stage #1: carbon monoxide; P-toluenesulfonyl cyanide; (Prop-2-ene-1-sulfonyl)-cyclohexane With 1,1'-azobis(1-cyanocyclohexanenitrile) In n-heptane at 100℃; under 98800 Torr;
Stage #2: methanol In n-heptane at 20℃;
A 80%
B 15%
dimethylbromosulphonium bromide
50450-21-0

dimethylbromosulphonium bromide

cyclohexylcarboxamide
1122-56-1

cyclohexylcarboxamide

A

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

B

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

Conditions
ConditionsYield
In acetonitrile for 3h; Reflux;A 80%
B n/a
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

2-ethyl-1-bromobutane
3814-34-4

2-ethyl-1-bromobutane

1-(2-ethylbutyl)cyclohexane-1-carbonitrile

1-(2-ethylbutyl)cyclohexane-1-carbonitrile

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With n-butyllithium; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide In tetrahydrofuran; hexane at -15 - 8℃;
Stage #2: 2-ethyl-1-bromobutane In tetrahydrofuran; hexane at 3 - 26℃; Product distribution / selectivity;
100%
Stage #1: cyclohexane carbonitrile With methylmagnesium chloride; diethylamine In tetrahydrofuran at 20 - 25℃; for 1.5h;
Stage #2: 2-ethyl-1-bromobutane In tetrahydrofuran at 45 - 50℃; for 2h; Product distribution / selectivity;
97.6%
With methylmagnesium chloride; diethylamine In tetrahydrofuran at 45.3 - 70.2℃; for 2.25h; Product distribution / selectivity; Inert atmosphere;95%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

allyl bromide
106-95-6

allyl bromide

1-allylcyclohexane-1-nitrile
676132-37-9

1-allylcyclohexane-1-nitrile

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: allyl bromide In tetrahydrofuran at -78 - 20℃; Inert atmosphere;
100%
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: allyl bromide In tetrahydrofuran at 20℃;
94%
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran Inert atmosphere;
Stage #2: allyl bromide Inert atmosphere;
90%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

aniline
62-53-3

aniline

N-(cyclohexylmethyl)aniline
79952-92-4

N-(cyclohexylmethyl)aniline

Conditions
ConditionsYield
With ammonium acetate; hydrogen; palladium on activated charcoal In methanol at 20℃; for 24h;100%
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr; for 24h;99%
ethanol
64-17-5

ethanol

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

ethyl cyclohexanecarboximidate hydrochloride
43002-69-3

ethyl cyclohexanecarboximidate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 0 - 20℃; for 12h; Inert atmosphere;100%
With hydrogenchloride In 1,4-dioxane at 20℃; for 48h;74%
With hydrogenchloride for 3h; Inert atmosphere; Cooling with ice;73%
methanol
67-56-1

methanol

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

methyl cyclohexanecarboximidate
66493-03-6

methyl cyclohexanecarboximidate

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether at 0℃; for 0.333333h;100%
With hydrogenchloride at 0℃; for 0.333333h;
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

cyclohexylcarboxamide
1122-56-1

cyclohexylcarboxamide

Conditions
ConditionsYield
With [RuH(tBu-PNP(-))(CO)]; water In tert-butyl alcohol at 50℃; for 24h;99%
With water; tricyclohexylphosphine; {Rh(OMe)(cod)}2 In isopropyl alcohol at 25℃; for 72h;96%
With N-ethyl-N-hydroxy-ethanamine; water; copper diacetate In ethanol at 35℃; for 3h;89%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

cyclohexylmethylamine
3218-02-8

cyclohexylmethylamine

Conditions
ConditionsYield
With [Ru(H)(BH4)(CO)(PPh3)(3-(di-tert-butylphosphino)-N-((1-methyl-1H-imidazol-2 yl)methyl)propylamine)]; hydrogen In isopropyl alcohol at 70℃; for 3h; Inert atmosphere; Autoclave;99%
With ammonia; hydrogen In toluene at 120℃; under 22502.3 Torr; for 16h; Autoclave;92%
With hydrogen In ethanol at 88℃; under 37503.8 Torr; for 0.5h;91%
benzyl bromide
100-39-0

benzyl bromide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

1-benzylcyclohexanecarbonitrile
104367-54-6

1-benzylcyclohexanecarbonitrile

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: benzyl bromide In tetrahydrofuran; hexane at -78 - 20℃;
99%
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran at -78 - 20℃; for 1h;
Stage #2: benzyl bromide With methyl cyanoformate In tetrahydrofuran at -78 - 20℃; for 2h; chemoselective reaction;
98%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

dimethyl sulfate
77-78-1

dimethyl sulfate

Phenyl azide
622-37-7

Phenyl azide

C14H18N4

C14H18N4

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: Phenyl azide With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran at -78 - 20℃; for 1h;
Stage #3: dimethyl sulfate at 20℃; for 1h;
99%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

dimethyl sulfate
77-78-1

dimethyl sulfate

Phenyl azide
622-37-7

Phenyl azide

C14H18N4

C14H18N4

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.333333h;
Stage #2: Phenyl azide With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran at -78 - 20℃; for 1h;
Stage #3: dimethyl sulfate at -78℃; for 1h;
99%
2-fluoropyridine
372-48-5

2-fluoropyridine

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

1-(pyridin-2-yl)cyclohexanecarbonitrile

1-(pyridin-2-yl)cyclohexanecarbonitrile

Conditions
ConditionsYield
With potassium hexamethylsilazane In toluene at 60℃; for 2h;99%
iodobenzene
591-50-4

iodobenzene

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Cyclohexyl phenyl ketone
712-50-5

Cyclohexyl phenyl ketone

Conditions
ConditionsYield
Stage #1: iodobenzene; cyclohexane carbonitrile With iodine; magnesium In tetrahydrofuran at 83 - 85℃;
Stage #2: With sulfuric acid In water at 20 - 25℃; for 2h;
99%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

o-toluidine
95-53-4

o-toluidine

2-cyclohexylcarbonyl-6-methylaniline
205990-43-8

2-cyclohexylcarbonyl-6-methylaniline

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile; o-toluidine With boron trichloride In toluene at 20℃; for 1h; Addition;
Stage #2: With aluminium trichloride In acetonitrile for 5h; Rearrangement; Heating;
Stage #3: With hydrogenchloride In acetonitrile for 2.5h; Hydrolysis; Heating;
98.4%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

aniline
62-53-3

aniline

N'-phenylcyclohexanecarboximidamide

N'-phenylcyclohexanecarboximidamide

Conditions
ConditionsYield
With aluminium trichloride98%
With aluminum (III) chloride at 120℃;
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

cyclohexanecarboximidamide hydrochloride
2498-48-8

cyclohexanecarboximidamide hydrochloride

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With hydrogenchloride; methanol In diethyl ether at 0℃;
Stage #2: With ammonia In ethanol
98%
Multi-step reaction with 2 steps
1: 31 g / HCl (gas) / diethyl ether; methanol / 0 °C
2: 9 g / NH3 / ethanol / 24 h / 0 °C
View Scheme
Stage #1: cyclohexane carbonitrile With hydrogenchloride; ethanol for 3h; Pinner Amidine Synthesis; Inert atmosphere; Cooling with ice;
Stage #2: With ammonia In methanol at 20℃; for 24h; Pinner Amidine Synthesis; Inert atmosphere;
835 mg
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

tert-butyl alcohol
75-65-0

tert-butyl alcohol

cyclohexanecarboxylic acid N-t-butylamide
6941-24-8

cyclohexanecarboxylic acid N-t-butylamide

Conditions
ConditionsYield
With 1-methyl-3-(4-sulfonylbutyl)-1H-imidazol-3-ium trifluoromethanesulfonate at 60℃; for 5h; Ritter reaction; Inert atmosphere; Ionic liquid;98%
With silica boron-sulfuric acid nanoparticles at 20℃; for 0.333333h; Ritter reaction; Neat (no solvent);91%
pinacolborane

pinacolborane

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

C23H45B2N

C23H45B2N

Conditions
ConditionsYield
With sodium triethylborohydride In neat (no solvent) at 20℃; for 3h; Inert atmosphere; Glovebox; Green chemistry;98%
bromobenzene
108-86-1

bromobenzene

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

Cyclohexyl phenyl ketone
712-50-5

Cyclohexyl phenyl ketone

Conditions
ConditionsYield
Stage #1: bromobenzene; cyclohexane carbonitrile With iodine; magnesium In tetrahydrofuran at 80 - 85℃;
Stage #2: With sulfuric acid In water at 20 - 25℃; for 2h;
98%
bromostyrene
103-64-0

bromostyrene

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

p-toluidine
106-49-0

p-toluidine

C29H33N3

C29H33N3

Conditions
ConditionsYield
With gallium(III) trichloride; 2,4-lutidine In 2-methyltetrahydrofuran; isopropyl alcohol at 85℃; for 4h; Reagent/catalyst; Solvent; Inert atmosphere;97.6%
4-(2-bromo-vinyl)-anisole
27570-08-7, 60592-52-1, 6303-59-9

4-(2-bromo-vinyl)-anisole

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

aniline
62-53-3

aniline

C29H33N3O

C29H33N3O

Conditions
ConditionsYield
With gallium(III) trichloride; 2,4-lutidine In 2-methyltetrahydrofuran; isopropyl alcohol at 70℃; for 6h; Reagent/catalyst; Solvent; Inert atmosphere;97.5%
1-(2-bromovinyl)-4-chlorobenzene
66482-29-9, 66482-30-2, 125428-11-7

1-(2-bromovinyl)-4-chlorobenzene

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

aniline
62-53-3

aniline

C28H30ClN3

C28H30ClN3

Conditions
ConditionsYield
With gallium(III) trichloride; 2,4-lutidine In 2-methyltetrahydrofuran; isopropyl alcohol at 80℃; for 5h; Reagent/catalyst; Solvent; Inert atmosphere;97.3%
(E)-(5-bromopent-3-en-2-yloxy)tertbutyldimethylsilane
1372806-96-6

(E)-(5-bromopent-3-en-2-yloxy)tertbutyldimethylsilane

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

C18H33NOSi
1372806-98-8

C18H33NOSi

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: (E)-(5-bromopent-3-en-2-yloxy)tertbutyldimethylsilane In tetrahydrofuran; hexane at -78 - 25℃;
97%
acetic acid tert-butyl ester
540-88-5

acetic acid tert-butyl ester

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

cyclohexanecarboxylic acid N-t-butylamide
6941-24-8

cyclohexanecarboxylic acid N-t-butylamide

Conditions
ConditionsYield
With silica sulfuric acid at 60℃; for 3.08333h; Reagent/catalyst; Temperature; Ritter Amidation; Green chemistry;97%
4-bromobut-1-yne
38771-21-0

4-bromobut-1-yne

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

1-(but-3-yn-1-yl)cyclohexane-1-carbonitrile

1-(but-3-yn-1-yl)cyclohexane-1-carbonitrile

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: 4-bromobut-1-yne In tetrahydrofuran; hexane at -78 - 24℃; for 14h; Inert atmosphere;
97%
cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

chlorobenzene
108-90-7

chlorobenzene

Cyclohexyl phenyl ketone
712-50-5

Cyclohexyl phenyl ketone

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile; chlorobenzene With iodine; magnesium In tetrahydrofuran at 85℃;
Stage #2: With sulfuric acid In water at 20 - 25℃; for 2h;
97%
methanol
67-56-1

methanol

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

methyl cyclohexanecarboximidate hydrochloride
94052-40-1

methyl cyclohexanecarboximidate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In hexane at 0℃; for 3h;96%
With hydrogenchloride; diethyl ether
With hydrogenchloride In methanol; diethyl ether at 0℃;31 g
2-Iodobenzyl bromide
40400-13-3

2-Iodobenzyl bromide

cyclohexane carbonitrile
766-05-2

cyclohexane carbonitrile

1-(2-iodobenzyl)cyclohexanecarbonitrile
445006-90-6

1-(2-iodobenzyl)cyclohexanecarbonitrile

Conditions
ConditionsYield
Stage #1: cyclohexane carbonitrile With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: 2-Iodobenzyl bromide In tetrahydrofuran; hexane at -78 - 20℃; Further stages.;
96%
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