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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Phthalimidocyclohexanone supplier in China

Cas:104618-32-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(4-Oxocyclohexyl)-1H-isoindole-1,3-(2H)-dione

Cas:104618-32-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

4-(PHTHALIMIDO)-CYCLOHEXANONE CAS 104618-32-8

Cas:104618-32-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 104618-32-8 with competitive price

Cas:104618-32-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 4-(phthalimide)-cyclohexanone Molecular Formula:C14H13NO3 Molecular Weight:243.26 CAS No.:104618-32-8 Appearance:White To Similar White Powder Appearance:White To Similar White Powder Storage:Store in cool and dry place, away from sun ligh

4-(phthalimide)-cyclohexanone

Cas:104618-32-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Isoindole-1,3(2H)-dione,2-(4-oxocyclohexyl)- 104618-32-8

Cas:104618-32-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

4-Phthalimidocyclohexanone CAS: 104618-32-8 Specificatio Item Standard Test Results Identification A.H-NMR:Comply with the structure Complies B.LC-MS:Comp

Factory supply 4-Phthalimidocyclohexanone

Cas:104618-32-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Isoindole-1,3(2H)-dione,2-(4-oxocyclohexyl)-

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Phthalimidocyclohexanone

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-PHTHALIMIDO-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Isoindole-1,3(2H)-dione,2-(4-oxocyclohexyl)-

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-phthalimido-cyclohexanone cas no. 104618-32-8 98%

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

4-Phthalimidocyclohexanone yclohexanone

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

N-(4-Oxocyclohexyl)phthaliMide

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

4-Phthalimidocyclohexanone

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1H-Isoindole-1,3(2H)-dione,2-(4-oxocyclohexyl)-

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

N-(4-Oxocyclohexyl)phthaliMide

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

4-(PHTHALIMIDO)-CYCLOHEXANONE CAS No.104618-32-8

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

4-(Phthalimido)-cyclohexanoneAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

4-(Phthalimido)-cyclohexanone

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Other

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers.Appearance:White solid Application:Pharm intermediate

N-(4-Oxocyclohexyl)phthalimide

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-(4-Oxo-cyclohexyl)-isoindole-1,3-dione

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

4-(Phthalimido)-Cyclohexanone manufacturer

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-(PHTHALIMIDO)-CYCLOHEXANONE

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Beantown Chemical

in stock Application:104618-32-8

4-Phthalimidocyclohexanone, 98%

Cas:104618-32-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-(1,4-dioxaspiro[4.5]decan-8-yl)isoindoline-1,3-dione
1252607-42-3

2-(1,4-dioxaspiro[4.5]decan-8-yl)isoindoline-1,3-dione

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid In tetrahydrofuran; water at 115℃; for 2h;100%
With water; toluene-4-sulfonic acid In tetrahydrofuran at 115℃; for 2h;100%
trans-2-(4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-31-7

trans-2-(4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide In ethyl acetate at 5 - 20℃; pH=7 - 8;95%
With potassium dichromate; sulfuric acid In chloroform; water at 25℃; for 4h;92.4%
With pyridinium chlorochromate In dichloromethane at 20℃; for 26h;88%
2-((1R,4R)-4-hydroxycyclohexyl) isoindoline-1,3-dione
99337-98-1

2-((1R,4R)-4-hydroxycyclohexyl) isoindoline-1,3-dione

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With 4 A molecular sieve; pyridinium chlorochromate In dichloromethane for 3h;95%
2-(trans-4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(trans-4-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With pyridinium chlorochromate In dichloromethane at 20℃; for 1.5h; Molecular sieve;76%
N-ethoxycarbonylphthalimide
22509-74-6

N-ethoxycarbonylphthalimide

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / aq. K2CO3 / 0.5 h / Ambient temperature
2: 95 percent / PCC, molecular sieves 4A / CH2Cl2 / 3 h
View Scheme
Multi-step reaction with 2 steps
2: 67 percent / pyridinium chlorochromate
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / water; tetrahydrofuran / 72 h / 20 °C
2: pyridinium chlorochromate / dichloromethane / 26 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / water / 0.5 h / 20 °C
2: pyridinium chlorochromate / dichloromethane / 1.5 h / 20 °C / Molecular sieve
View Scheme

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86 percent / aq. K2CO3 / 0.5 h / Ambient temperature
2: 95 percent / PCC, molecular sieves 4A / CH2Cl2 / 3 h
View Scheme

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 67 percent / pyridinium chlorochromate
View Scheme
4,4-ethylenedioxycyclohexan-1-ol
22428-87-1

4,4-ethylenedioxycyclohexan-1-ol

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0 - 20 °C
2: toluene-4-sulfonic acid / water; tetrahydrofuran / 2 h / 115 °C
View Scheme
Multi-step reaction with 2 steps
1: diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran; toluene / 16 h / 0 - 20 °C
2: toluene-4-sulfonic acid; water / tetrahydrofuran / 2 h / 115 °C
View Scheme
cyclohexanedione monoethylene ketal
4746-97-8

cyclohexanedione monoethylene ketal

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tetrahydroborate; methanol / 2 h / 20 °C
2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0 - 20 °C
3: toluene-4-sulfonic acid / water; tetrahydrofuran / 2 h / 115 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / 2 h / 20 °C
2: diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran; toluene / 16 h / 0 - 20 °C
3: toluene-4-sulfonic acid; water / tetrahydrofuran / 2 h / 115 °C
View Scheme
trans-4-hydroxycyclohexylamine hydrochloride

trans-4-hydroxycyclohexylamine hydrochloride

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / water; tetrahydrofuran / 72 h / 20 °C
2: pyridinium chlorochromate / dichloromethane / 26 h / 20 °C
View Scheme
trans-4-hydroxycyclohexylamine hydrochloride

trans-4-hydroxycyclohexylamine hydrochloride

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / water / 0.5 h / 20 °C
2: pyridinium chlorochromate / dichloromethane / 1.5 h / 20 °C / Molecular sieve
View Scheme
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

(4-bromophenyl)hydrazine
589-21-9

(4-bromophenyl)hydrazine

Conditions
ConditionsYield
In ethanol at 20℃; for 2h;100%

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-{4-[2-(6-bromopyridin-2-yl)hydrazineylidene]cyclohexyl}isoindoline-1,3-dione
1342810-88-1

2-{4-[2-(6-bromopyridin-2-yl)hydrazineylidene]cyclohexyl}isoindoline-1,3-dione

Conditions
ConditionsYield
In ethanol at 20℃; for 1h; Product distribution / selectivity;100%
In ethanol at 20℃; for 1h;100%
4-methoxyphenylhydrazine hydrochloride
19501-58-7

4-methoxyphenylhydrazine hydrochloride

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

N-(6-methoxy-1,2,3,4-tetrahydrocarbazol-3-yl)phthalimide
147009-21-0

N-(6-methoxy-1,2,3,4-tetrahydrocarbazol-3-yl)phthalimide

Conditions
ConditionsYield
In ethanol for 2.5h; Fischer Indole Synthesis; Reflux;97%
In ethanol for 1h; Heating;83%
In ethanol
In ethanol
In ethanol
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

4-Methoxyphenylhydrazine
3471-32-7

4-Methoxyphenylhydrazine

N-(6-methoxy-1,2,3,4-tetrahydrocarbazol-3-yl)phthalimide
147009-21-0

N-(6-methoxy-1,2,3,4-tetrahydrocarbazol-3-yl)phthalimide

Conditions
ConditionsYield
With acetic acid for 2h; Heating;96%
4-chloro-aniline
106-47-8

4-chloro-aniline

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-((4-chlorophenyl)amino)-5-oxocyclohex-3-en-1-yl)isoindoline-1,3-dione

2-(4-((4-chlorophenyl)amino)-5-oxocyclohex-3-en-1-yl)isoindoline-1,3-dione

Conditions
ConditionsYield
With silver hexafluoroantimonate; 2,2,6,6-tetramethylpiperidine-1-oxoammonium hexafluorophosphate In 1,2-dichloro-ethane at 20℃; for 24h; Glovebox; Molecular sieve; Sealed tube; Inert atmosphere;93%
thiourea
17356-08-0

thiourea

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-Amino-6-phthalimido-4,5,6,7-tetrahydrobenzothiazole hydroiodide
916334-22-0

2-Amino-6-phthalimido-4,5,6,7-tetrahydrobenzothiazole hydroiodide

Conditions
ConditionsYield
With iodine In isopropyl alcohol for 24h; Heating / reflux;92%
1-phenylmethylpiperazine
2759-28-6

1-phenylmethylpiperazine

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-[4-(4-benzyl-1-piperazinyl)cyclohexyl]-1H-isoindole-1,3(2H)-dione

2-[4-(4-benzyl-1-piperazinyl)cyclohexyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid In 1,1-dichloroethane89%

Conditions
ConditionsYield
In ethanol for 2h; Heating;80%
1-(4-iodobenzyl)-1-phenylhydrazine
1344674-97-0

1-(4-iodobenzyl)-1-phenylhydrazine

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-(2-(4-iodobenzyl)-2-phenylhydrazono)cyclohexyl)isoindoline-1,3-dione
1344674-60-7

2-(4-(2-(4-iodobenzyl)-2-phenylhydrazono)cyclohexyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With acetic acid In ethanol at 60℃; for 3h;79%
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

4-(methylsulfonyl)phenylhydrazine
877-66-7

4-(methylsulfonyl)phenylhydrazine

N-[6-(methylsulfonyl)-1,2,3,4-tetrahydrocarbazol-3-yl]phthalimide

N-[6-(methylsulfonyl)-1,2,3,4-tetrahydrocarbazol-3-yl]phthalimide

Conditions
ConditionsYield
With acetic acid for 47h; Reflux;79%
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

4R-4-hydroxyproline
51-35-4

4R-4-hydroxyproline

2-(cis-9-oxo-5,6,7,8,8a,9-hexahydro-4aH-pyrrolo[1,2-a]indol-7-yl)isoindoline-1,3-dione

2-(cis-9-oxo-5,6,7,8,8a,9-hexahydro-4aH-pyrrolo[1,2-a]indol-7-yl)isoindoline-1,3-dione

Conditions
ConditionsYield
With propionic acid In toluene at 140℃; for 12h; Inert atmosphere; Schlenk technique; stereoselective reaction;77%
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

C14H12BrNO3
202058-46-6

C14H12BrNO3

Conditions
ConditionsYield
With bromine; aluminum (III) chloride In methanol; ethyl acetate at 0℃; for 0.166667 - 0.25h; Product distribution / selectivity;75.2%
With bromine; aluminum (III) chloride In methanol at 40℃; for 0.166667 - 0.25h; Product distribution / selectivity;62.8%
With bromine; aluminum (III) chloride In dichloromethane at 0℃; for 0.166667 - 0.25h; Product distribution / selectivity;
methanol
67-56-1

methanol

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(4-hydroxycyclohexyl)-3-methoxyisoindolin-1-one

2-(4-hydroxycyclohexyl)-3-methoxyisoindolin-1-one

Conditions
ConditionsYield
With tris(2,4-pentanedionato)ruthenium(III); methanesulfonic acid; hydrogen; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] at 130℃; under 11251.1 Torr; for 18h; Autoclave;75%
4-aminobenzamide
2835-68-9

4-aminobenzamide

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

(+/-)-6-carboxamido-3-phthalimido-1,2,3,4-tetrahydrocarbazole
147009-23-2

(+/-)-6-carboxamido-3-phthalimido-1,2,3,4-tetrahydrocarbazole

Conditions
ConditionsYield
Stage #1: 4-aminobenzamide With hydrogenchloride; sodium nitrite; toluene-4-sulfonic acid In water at -10 - 10℃; Industry scale;
Stage #2: With sodium sulfite In water at -10 - 20℃; for 17h;
Stage #3: 2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione In methanol; water at 25 - 75℃; Fisher Indole reaction;
70%
tert-butyl α-benzyl-α-diazoacetate
850147-87-4

tert-butyl α-benzyl-α-diazoacetate

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

tert-butyl trans-1-benzyl-2-oxo-5-(N-phthaloylamino)cycloheptanecarboxylate

tert-butyl trans-1-benzyl-2-oxo-5-(N-phthaloylamino)cycloheptanecarboxylate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at -78℃; for 0.5h; Inert atmosphere; optical yield given as %de; diastereoselective reaction;69%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

4-(1,3-dioxoiso indolin-2-yl)cyclohex-1-en-1-yl trifluoromethanesulfonate

4-(1,3-dioxoiso indolin-2-yl)cyclohex-1-en-1-yl trifluoromethanesulfonate

Conditions
ConditionsYield
With 2,6-di-tert-butyl-4-methylpyridine In dichloromethane at 20℃;67%
4-hydrazinobenzonitrile hydrochloride
2863-98-1

4-hydrazinobenzonitrile hydrochloride

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

3-phthalimido-6-cyano-1,2,3,4-tetrahydrocarbazole
147009-18-5

3-phthalimido-6-cyano-1,2,3,4-tetrahydrocarbazole

Conditions
ConditionsYield
With sodium acetate; acetic acid60%
With sodium acetate In acetic acid
1H-indazol-5-ylamine
19335-11-6

1H-indazol-5-ylamine

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(7-(4-hydroxyphenyl)-8,9,10,11-tetrahydro-3H-pyrazolo[4,3-a]phenanthridin-9-yl)isoindoline-1,3-dione

2-(7-(4-hydroxyphenyl)-8,9,10,11-tetrahydro-3H-pyrazolo[4,3-a]phenanthridin-9-yl)isoindoline-1,3-dione

Conditions
ConditionsYield
With hydrogenchloride In ethanol for 12h; Reflux;52%
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

N-(2-diazo)acetyl (+)-camphorsultam

N-(2-diazo)acetyl (+)-camphorsultam

N-[(2S,5S)-1-oxo-5-(N-phthaloylamino)cycloheptan-2-carbonyl] (+)-camphorsultam
1253124-69-4

N-[(2S,5S)-1-oxo-5-(N-phthaloylamino)cycloheptan-2-carbonyl] (+)-camphorsultam

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at -78℃; for 6h; Inert atmosphere; stereoselective reaction;40%
ethanol
64-17-5

ethanol

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

A

C16H15NO4

C16H15NO4

B

C16H15NO4

C16H15NO4

Conditions
ConditionsYield
With iodine; copper(II) oxide at 100℃; for 12h;A 22%
B 34%
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

adamantan-2-one O-methyloxime
76300-15-7

adamantan-2-one O-methyloxime

cis-adamantane-2-spiro-3'-8'-phthalimido-1',2',4'-trioxaspiro[4.5]decane

cis-adamantane-2-spiro-3'-8'-phthalimido-1',2',4'-trioxaspiro[4.5]decane

Conditions
ConditionsYield
With ozone In dichloromethane; pentane at 0℃; for 0.05h; Griesbaum coozonolysis reaction;29%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(((4-((trimethylsilyl)oxy)cyclohex-3-en-1-yl)-λ2-azaneyl)carbonyl)benzoic acid

2-(((4-((trimethylsilyl)oxy)cyclohex-3-en-1-yl)-λ2-azaneyl)carbonyl)benzoic acid

Conditions
ConditionsYield
Stage #1: 2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione With lithium diisopropyl amide In tetrahydrofuran at -78 - 20℃; for 0.333333h;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78 - 20℃; for 1.5h;
27.76%
thiourea
17356-08-0

thiourea

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)isoindoline-1,3-dione
104618-33-9

2-(2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)isoindoline-1,3-dione

Conditions
ConditionsYield
With bromine In ethanol at 5 - 78℃; for 8h;
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

2-(6-Hydroxy-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-isoindole-1,3-dione
171783-42-9

2-(6-Hydroxy-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-isoindole-1,3-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 83 percent / ethanol / 1 h / Heating
2: 31 percent
View Scheme
Multi-step reaction with 2 steps
1: 96 percent / HOAc / 2 h / Heating
2: 20 percent / BBr3 / CHCl3 / 1.) -78 deg C, 2 h, 2.) RT, overnight
View Scheme
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

Trifluoro-methanesulfonic acid 6-amino-6,7,8,9-tetrahydro-5H-carbazol-3-yl ester

Trifluoro-methanesulfonic acid 6-amino-6,7,8,9-tetrahydro-5H-carbazol-3-yl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 83 percent / ethanol / 1 h / Heating
2: 31 percent
3: 62 percent / Et3N / CH2Cl2 / 24 h
4: 1.) N2H4*H2O / 1.) EtOH, room temperature, 0.5 h, 2.) CHCl3, reflux, 0.5 h
View Scheme
2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
104618-32-8

2-(4-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione

3-Amino-6-methoxy-1,2,3,4-tetrahydrocarbazole hydrochloride

3-Amino-6-methoxy-1,2,3,4-tetrahydrocarbazole hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 83 percent / ethanol / 1 h / Heating
2: 1.) N2H4*H2O / 1.) EtOH, room temperature, 0.5 h, 2.) CHCl3, reflux, 0.5 h
View Scheme

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