DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:104632-25-9
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inquiryJinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu
Cas:104632-25-9
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inquiryPramipexole dihydrochloride CAS 104632-25-9 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals
Cas:104632-25-9
Min.Order:1 Kilogram
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Type:Trading Company
inquiryhigh quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
Cas:104632-25-9
Min.Order:1 Kilogram
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:104632-25-9
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:104632-25-9
Min.Order:1 Gram
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Type:Manufacturers
inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:104632-25-9
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inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:104632-25-9
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Type:Trading Company
inquiryOur company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:104632-25-9
Min.Order:1 Metric Ton
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Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:104632-25-9
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:104632-25-9
Min.Order:10 Kilogram
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inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:104632-25-9
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inquiryName Pramipexole dihydrochloride CAS NO. 104632-25-9 Molecular Formula C10H19Cl2N3S Molecular Weight 284.25 EINEC
Cas:104632-25-9
Min.Order:1 Metric Ton
FOB Price: $1.0
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inquiry1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;
Cas:104632-25-9
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Type:Trading Company
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool &
Cas:104632-25-9
Min.Order:100 Gram
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Type:Other
inquiryPramipexole Di-Hcl Monohydrate CAS:191217-81-9 Pramipexole 2HCl CAS:104632-25-9 Pramipexole CAS:104632-26-0 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about
Cas:104632-25-9
Min.Order:1 Kilogram
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Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:104632-25-9
Min.Order:1 Kilogram
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:104632-25-9
Min.Order:1 Kilogram
FOB Price: $900.0 / 1000.0
Type:Trading Company
inquiryPramipexole Impurity 4 CAS: 104632-25-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:104632-25-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:104632-25-9
Min.Order:1 Kilogram
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:104632-25-9
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Type:Lab/Research institutions
inquiryMain Service 1.Own made fine chemical products 2.Out sourcing and quality controlling service in China 3. COM for Chemical synthesis 4.Lab custom synthesis of API and intermadiates Quality Assurance 1. NMR,HPLC and COA can
Cas:104632-25-9
Min.Order:10 Gram
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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inquiryOur company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
Cas:104632-25-9
Min.Order:1 Gram
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:104632-25-9
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:104632-25-9
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inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:104632-25-9
Min.Order:100 Gram
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Type:Other
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:104632-25-9
Min.Order:10 Gram
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Type:Lab/Research institutions
inquiryPramipexole dihydrochlorideAppearance:White or Almost White crystalline powder Storage:Store in refrigerator Package:according to customers' requirements Application:Steroids injection For Body building Transportation:By air(EMS or EUB or FedEx or TN
supplier in China Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum;200kg/drum as per your request Application:A dopamine-D2-receptor agonist. Antiparkinsonian Trans
Cas:104632-25-9
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiry(S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Stage #1: (S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole With potassium borohydride; triethylamine; lithium chloride In tetrahydrofuran at 20℃; for 7h; Inert atmosphere; Reflux; Stage #2: With hydrogenchloride at -5 - 20℃; for 5h; Reagent/catalyst; Solvent; Temperature; Reflux; | 78.2% |
Stage #1: (S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole With chloro-trimethyl-silane In dichloromethane at 0 - 15℃; Inert atmosphere; Stage #2: With lithium aluminium tetrahydride In tetrahydrofuran; dichloromethane at -10 - 0℃; Inert atmosphere; | 72% |
Multi-step reaction with 2 steps 1.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C 1.2: 0.17 h / 10 °C 2.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C View Scheme | |
Stage #1: (S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole With sodium bis(2-methoxyethoxy)aluminium dihydride In toluene at 80℃; for 6h; Stage #2: With hydrogenchloride In water; isopropyl alcohol at 20℃; under 75.0075 Torr; for 1h; Temperature; Pressure; |
2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole p-toluenesulfonic acid
pramipexole dihydrochloride
Conditions | Yield |
---|---|
With acetyl chloride In isopropyl alcohol at 5 - 20℃; for 12.5h; | 86% |
Stage #1: 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole p-toluenesulfonic acid With hydrogenchloride In water at 0℃; for 0.25h; Stage #2: With sodium hydroxide In water at 0℃; for 3h; | 78% |
(S)-t-butyl-2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl(propyl)carbamate
pramipexole dihydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In tetrahydrofuran at 20 - 25℃; for 12h; | 85% |
pramipexole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In water; acetone at 0 - 3℃; for 2h; pH=1.5; Product distribution / selectivity; | 98% |
With hydrogenchloride In water; isopropyl alcohol at 20℃; for 2h; | 95.8% |
With hydrogenchloride In water; acetone at 20℃; for 3h; Large scale; | 90.9% |
pramipexole (HCl)
pramipexole dihydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride; water In methanol at 3 - 8℃; for 2h; | 36% |
(6S,7S)-2-amino-7-hydroxy-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Stage #1: (6S,7S)-2-amino-7-hydroxy-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazole With hydrogenchloride; formic acid In water Stage #2: With hydrogen; palladium on activated carbon In water Product distribution / selectivity; | 87% |
propionaldehyde
(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Stage #1: propionaldehyde; (S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine With sulfuric acid In methanol at 0℃; Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃; Stage #3: With hydrogenchloride In ethanol at 0℃; for 8h; |
(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: triethylamine / methanol / 1.5 h / 10 - 20 °C 2.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C 2.2: 0.17 h / 10 °C 3.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 2.1: hydrogenchloride / water / 0.25 h / 0 °C 2.2: 3 h / 0 °C View Scheme | |
Multi-step reaction with 3 steps 1: sulfuric acid; sodium tetrahydroborate / dichloromethane; methanol / 3 - 8 °C 2: hydrogenchloride / water 3: hydrogenchloride; water / methanol / 2 h / 3 - 8 °C View Scheme |
N-(4-oxocyclohexyl)acetamide
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1.1: bromine; acetic acid / 0.75 h / 25 - 35 °C 1.2: 3 h / Reflux 2.1: water; sulfuric acid / 10 h / Reflux 2.2: 1.5 h / 0 - 30 °C 3.1: water / 70 °C / Reflux; Resolution of racemate 4.1: hydrogenchloride / water / carbon treatment 4.2: 1.5 h / 25 - 30 °C 5.1: triethylamine / methanol / 1.5 h / 10 - 20 °C 6.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C 6.2: 0.17 h / 10 °C 7.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: bromine / water / 2 h / 45 - 80 °C / Large scale 1.2: 3 h / Reflux; Large scale 2.1: ethanol / 5 h / 50 °C 3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 6 h / 80 °C 3.2: 1 h / 20 °C / 75.01 Torr View Scheme |
2,6-diamino-4,5,6,7-tetrahydro-benzthiazole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: water / 70 °C / Reflux; Resolution of racemate 2.1: hydrogenchloride / water / carbon treatment 2.2: 1.5 h / 25 - 30 °C 3.1: triethylamine / methanol / 1.5 h / 10 - 20 °C 4.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C 4.2: 0.17 h / 10 °C 5.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C View Scheme |
N-(2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)acetamide hydrobromide
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: water; sulfuric acid / 10 h / Reflux 1.2: 1.5 h / 0 - 30 °C 2.1: water / 70 °C / Reflux; Resolution of racemate 3.1: hydrogenchloride / water / carbon treatment 3.2: 1.5 h / 25 - 30 °C 4.1: triethylamine / methanol / 1.5 h / 10 - 20 °C 5.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C 5.2: 0.17 h / 10 °C 6.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C View Scheme |
(S)-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine tartrate trihydrate
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: hydrogenchloride / water / carbon treatment 1.2: 1.5 h / 25 - 30 °C 2.1: triethylamine / methanol / 1.5 h / 10 - 20 °C 3.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C 3.2: 0.17 h / 10 °C 4.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C View Scheme |
2-amino-6-oxo-4,5,6,7-tetrahydrobenzothiazole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: 0.5 h / 100 °C 2.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7 3.1: pyridine / 2 h / 0 - 20 °C 4.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 5.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 6.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 7.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 8.1: hydrogenchloride / water / 0.25 h / 0 °C 8.2: 3 h / 0 °C View Scheme |
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: pyridine / 2 h / 0 - 20 °C 2.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 3.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 4.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 5.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 6.1: hydrogenchloride / water / 0.25 h / 0 °C 6.2: 3 h / 0 °C View Scheme |
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 2.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 3.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 4.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 5.1: hydrogenchloride / water / 0.25 h / 0 °C 5.2: 3 h / 0 °C View Scheme |
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 2.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 3.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 4.1: hydrogenchloride / water / 0.25 h / 0 °C 4.2: 3 h / 0 °C View Scheme |
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 3.1: hydrogenchloride / water / 0.25 h / 0 °C 3.2: 3 h / 0 °C View Scheme |
cyclohexanedione monoethylene ketal
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 11 steps 1.1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere 2.1: sodium acetate; N-Bromosuccinimide / tetrahydrofuran; water / 2 h / 20 °C 2.2: 20 - 80 °C 3.1: hydrogenchloride; water / tetrahydrofuran / 4 h / Reflux 4.1: 0.5 h / 100 °C 5.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7 6.1: pyridine / 2 h / 0 - 20 °C 7.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 8.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 9.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 10.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 11.1: hydrogenchloride / water / 0.25 h / 0 °C 11.2: 3 h / 0 °C View Scheme |
1,4-cyclohexanedione-1-ethylene acetal 4-trimethylsilyl enol ether
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1.1: sodium acetate; N-Bromosuccinimide / tetrahydrofuran; water / 2 h / 20 °C 1.2: 20 - 80 °C 2.1: hydrogenchloride; water / tetrahydrofuran / 4 h / Reflux 3.1: 0.5 h / 100 °C 4.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7 5.1: pyridine / 2 h / 0 - 20 °C 6.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 7.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 8.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 9.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 10.1: hydrogenchloride / water / 0.25 h / 0 °C 10.2: 3 h / 0 °C View Scheme |
2-amino-6-(ethylenedioxy)-4,5,6,7-tetrahydrobenzothiazole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1.1: hydrogenchloride; water / tetrahydrofuran / 4 h / Reflux 2.1: 0.5 h / 100 °C 3.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7 4.1: pyridine / 2 h / 0 - 20 °C 5.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 6.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 7.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 8.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 9.1: hydrogenchloride / water / 0.25 h / 0 °C 9.2: 3 h / 0 °C View Scheme |
2-Acetylamino-6-oxo-4,5,6,7-tetrahydrobenzothiazole
pramipexole dihydrochloride
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7 2.1: pyridine / 2 h / 0 - 20 °C 3.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere 4.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C 5.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C 6.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide 7.1: hydrogenchloride / water / 0.25 h / 0 °C 7.2: 3 h / 0 °C View Scheme |
pramipexole dihydrochloride
pramipexole
Conditions | Yield |
---|---|
With potassium hydroxide In water at 20℃; for 1 - 2h; Product distribution / selectivity; | 86% |
With sodium hydroxide In water |
di-tert-butyl dicarbonate
pramipexole dihydrochloride
trifluoroacetic acid
Conditions | Yield |
---|---|
Stage #1: di-tert-butyl dicarbonate; pramipexole dihydrochloride With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 20℃; for 3h; Stage #2: trifluoroacetic acid In water | 422 mg |
Conditions | Yield |
---|---|
Stage #1: BOC-glycine; pramipexole dihydrochloride With 4-methyl-morpholine; (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate In dimethyl sulfoxide for 1h; Stage #2: With hydrogenchloride In methanol; water for 4h; | 490 mg |
Conditions | Yield |
---|---|
Stage #1: BOC-glycine; pramipexole dihydrochloride With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dimethyl sulfoxide for 1h; Stage #2: trifluoroacetic acid In water | 721 mg |
pramipexole dihydrochloride
trifluoroacetic acid
Conditions | Yield |
---|---|
Stage #1: C25H25NO3S; pramipexole dihydrochloride With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dimethyl sulfoxide for 16h; Stage #2: trifluoroacetic acid In water; acetonitrile | 21 mg |
pramipexole dihydrochloride
trifluoroacetic acid
Conditions | Yield |
---|---|
Stage #1: C34H42N2O5S; pramipexole dihydrochloride With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dimethyl sulfoxide for 0.666667h; Stage #2: trifluoroacetic acid In water; acetonitrile | 38 mg |
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