Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Pramipexole dihydrochloride Manufacturer/High quality/Best price/In stock

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu

Pramipexole HCl 104632-25-9 API

Cas:104632-25-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Pramipexole dihydrochloride CAS 104632-25-9 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals

Pramipexole dihydrochloride CAS 104632-25-9

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $50.0

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Pramipexole Dihydrochloride

Cas:104632-25-9

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Pramipexole Impurity 4 104632-25-9 GMP Manufacturer

Cas:104632-25-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

PramipexoleDihcl

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Pramipexole Impurity 4

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Pramipexole dihydrochloride 104632-25-9

Cas:104632-25-9

Min.Order:1 Metric Ton

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 104632-25-9 with competitive price

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

2, 6-benzothiazole diamine, 4, 5, 6, 7-tetrahydron-propyl hydrochloride CAS104632-25-9

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $290.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name Pramipexole dihydrochloride CAS NO. 104632-25-9 Molecular Formula C10H19Cl2N3S Molecular Weight 284.25 EINEC

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Other

inquiry

Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool &

Pramipexole Powder Dihydrochloride CAS 104632-25-9

Cas:104632-25-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hangzhou Think Chemical Co. Ltd

Pramipexole Di-Hcl Monohydrate CAS:191217-81-9 Pramipexole 2HCl CAS:104632-25-9 Pramipexole CAS:104632-26-0 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about

Pramipexole Dihydrochloride or Pramipexole Di-Hcl Monohydrate

Cas:104632-25-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6S)- 104632-25-9

Cas:104632-25-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:1 Kilogram

FOB Price: $900.0 / 1000.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Pramipexole Impurity 4 CAS: 104632-25-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

Pramipexole Impurity 4 CAS: 104632-25-9

Cas:104632-25-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6S)-

Cas:104632-25-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,6-Benzothiazolediamine,4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6S)-

Cas:104632-25-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Main Service 1.Own made fine chemical products 2.Out sourcing and quality controlling service in China 3. COM for Chemical synthesis 4.Lab custom synthesis of API and intermadiates Quality Assurance 1. NMR,HPLC and COA can

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:10 Gram

FOB Price: $1.0 / 10.0

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Pramipexole Dihydrochloride 104632-25-9

Cas:104632-25-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Pramipexole Dihydrochloride Manufacturer

Cas:104632-25-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Pramipexole dihydrochlorideAppearance:White or Almost White crystalline powder Storage:Store in refrigerator Package:according to customers' requirements Application:Steroids injection For Body building Transportation:By air(EMS or EUB or FedEx or TN

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

supplier in China Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum;200kg/drum as per your request Application:A dopamine-D2-receptor agonist. Antiparkinsonian Trans

Pramipexole dihydrochloride

Cas:104632-25-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

(S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole
106006-84-2

(S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Stage #1: (S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole With potassium borohydride; triethylamine; lithium chloride In tetrahydrofuran at 20℃; for 7h; Inert atmosphere; Reflux;
Stage #2: With hydrogenchloride at -5 - 20℃; for 5h; Reagent/catalyst; Solvent; Temperature; Reflux;
78.2%
Stage #1: (S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole With chloro-trimethyl-silane In dichloromethane at 0 - 15℃; Inert atmosphere;
Stage #2: With lithium aluminium tetrahydride In tetrahydrofuran; dichloromethane at -10 - 0℃; Inert atmosphere;
72%
Multi-step reaction with 2 steps
1.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C
1.2: 0.17 h / 10 °C
2.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C
View Scheme
Stage #1: (S)‑2‑amino‑6‑propionamido‑4,5,6,7‑tetrahydrobenzothiazole With sodium bis(2-methoxyethoxy)aluminium dihydride In toluene at 80℃; for 6h;
Stage #2: With hydrogenchloride In water; isopropyl alcohol at 20℃; under 75.0075 Torr; for 1h; Temperature; Pressure;
2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole p-toluenesulfonic acid
943319-02-6

2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole p-toluenesulfonic acid

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
With acetyl chloride In isopropyl alcohol at 5 - 20℃; for 12.5h;86%
Stage #1: 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole p-toluenesulfonic acid With hydrogenchloride In water at 0℃; for 0.25h;
Stage #2: With sodium hydroxide In water at 0℃; for 3h;
78%
(S)-t-butyl-2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl(propyl)carbamate
1265141-51-2

(S)-t-butyl-2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl(propyl)carbamate

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran at 20 - 25℃; for 12h;85%
pramipexole
104632-26-0

pramipexole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water; acetone at 0 - 3℃; for 2h; pH=1.5; Product distribution / selectivity;98%
With hydrogenchloride In water; isopropyl alcohol at 20℃; for 2h;95.8%
With hydrogenchloride In water; acetone at 20℃; for 3h; Large scale;90.9%
pramipexole (HCl)
943319-04-8

pramipexole (HCl)

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water In methanol at 3 - 8℃; for 2h;36%
(6S,7S)-2-amino-7-hydroxy-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazole
1001648-71-0

(6S,7S)-2-amino-7-hydroxy-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Stage #1: (6S,7S)-2-amino-7-hydroxy-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazole With hydrogenchloride; formic acid In water
Stage #2: With hydrogen; palladium on activated carbon In water Product distribution / selectivity;
87%
propionaldehyde
123-38-6

propionaldehyde

(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine
106092-09-5

(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Stage #1: propionaldehyde; (S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine With sulfuric acid In methanol at 0℃;
Stage #2: With sodium tetrahydroborate In methanol at 0 - 20℃;
Stage #3: With hydrogenchloride In ethanol at 0℃; for 8h;
(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine
106092-09-5

(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / methanol / 1.5 h / 10 - 20 °C
2.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C
2.2: 0.17 h / 10 °C
3.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C
View Scheme
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
2.1: hydrogenchloride / water / 0.25 h / 0 °C
2.2: 3 h / 0 °C
View Scheme
Multi-step reaction with 3 steps
1: sulfuric acid; sodium tetrahydroborate / dichloromethane; methanol / 3 - 8 °C
2: hydrogenchloride / water
3: hydrogenchloride; water / methanol / 2 h / 3 - 8 °C
View Scheme
N-(4-oxocyclohexyl)acetamide
27514-08-5

N-(4-oxocyclohexyl)acetamide

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: bromine; acetic acid / 0.75 h / 25 - 35 °C
1.2: 3 h / Reflux
2.1: water; sulfuric acid / 10 h / Reflux
2.2: 1.5 h / 0 - 30 °C
3.1: water / 70 °C / Reflux; Resolution of racemate
4.1: hydrogenchloride / water / carbon treatment
4.2: 1.5 h / 25 - 30 °C
5.1: triethylamine / methanol / 1.5 h / 10 - 20 °C
6.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C
6.2: 0.17 h / 10 °C
7.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: bromine / water / 2 h / 45 - 80 °C / Large scale
1.2: 3 h / Reflux; Large scale
2.1: ethanol / 5 h / 50 °C
3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 6 h / 80 °C
3.2: 1 h / 20 °C / 75.01 Torr
View Scheme
2,6-diamino-4,5,6,7-tetrahydro-benzthiazole
106006-83-1

2,6-diamino-4,5,6,7-tetrahydro-benzthiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: water / 70 °C / Reflux; Resolution of racemate
2.1: hydrogenchloride / water / carbon treatment
2.2: 1.5 h / 25 - 30 °C
3.1: triethylamine / methanol / 1.5 h / 10 - 20 °C
4.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C
4.2: 0.17 h / 10 °C
5.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C
View Scheme
N-(2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)acetamide hydrobromide
104617-50-7

N-(2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)acetamide hydrobromide

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: water; sulfuric acid / 10 h / Reflux
1.2: 1.5 h / 0 - 30 °C
2.1: water / 70 °C / Reflux; Resolution of racemate
3.1: hydrogenchloride / water / carbon treatment
3.2: 1.5 h / 25 - 30 °C
4.1: triethylamine / methanol / 1.5 h / 10 - 20 °C
5.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C
5.2: 0.17 h / 10 °C
6.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C
View Scheme
(S)-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine tartrate trihydrate
873431-80-2

(S)-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine tartrate trihydrate

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: hydrogenchloride / water / carbon treatment
1.2: 1.5 h / 25 - 30 °C
2.1: triethylamine / methanol / 1.5 h / 10 - 20 °C
3.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / 0 - 50 °C
3.2: 0.17 h / 10 °C
4.1: hydrogenchloride / water; methanol / 0.75 h / 25 - 30 °C
View Scheme
2-amino-6-oxo-4,5,6,7-tetrahydrobenzothiazole
113030-24-3

2-amino-6-oxo-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: 0.5 h / 100 °C
2.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7
3.1: pyridine / 2 h / 0 - 20 °C
4.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
5.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
6.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
7.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
8.1: hydrogenchloride / water / 0.25 h / 0 °C
8.2: 3 h / 0 °C
View Scheme
(R)-2-acetylamino-6-hydroxy-4,5,6,7-tetrahydrobenzothiazole

(R)-2-acetylamino-6-hydroxy-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: pyridine / 2 h / 0 - 20 °C
2.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
3.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
4.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
5.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
6.1: hydrogenchloride / water / 0.25 h / 0 °C
6.2: 3 h / 0 °C
View Scheme
(R)-2-acetylamino-6-hydroxy-4,5,6,7-tetrahydrobenzothiazole, 6-tosylate

(R)-2-acetylamino-6-hydroxy-4,5,6,7-tetrahydrobenzothiazole, 6-tosylate

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
2.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
3.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
4.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
5.1: hydrogenchloride / water / 0.25 h / 0 °C
5.2: 3 h / 0 °C
View Scheme
(S)-2-acetylamino-6-azido-4,5,6,7-tetrahydrobenzothiazole

(S)-2-acetylamino-6-azido-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
2.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
3.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
4.1: hydrogenchloride / water / 0.25 h / 0 °C
4.2: 3 h / 0 °C
View Scheme
(S)-2-acetylamino-6-amino-4,5,6,7-tetrahydrobenzothiazole

(S)-2-acetylamino-6-amino-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
3.1: hydrogenchloride / water / 0.25 h / 0 °C
3.2: 3 h / 0 °C
View Scheme
cyclohexanedione monoethylene ketal
4746-97-8

cyclohexanedione monoethylene ketal

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1.1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere
2.1: sodium acetate; N-Bromosuccinimide / tetrahydrofuran; water / 2 h / 20 °C
2.2: 20 - 80 °C
3.1: hydrogenchloride; water / tetrahydrofuran / 4 h / Reflux
4.1: 0.5 h / 100 °C
5.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7
6.1: pyridine / 2 h / 0 - 20 °C
7.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
8.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
9.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
10.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
11.1: hydrogenchloride / water / 0.25 h / 0 °C
11.2: 3 h / 0 °C
View Scheme
1,4-cyclohexanedione-1-ethylene acetal 4-trimethylsilyl enol ether
144810-01-5

1,4-cyclohexanedione-1-ethylene acetal 4-trimethylsilyl enol ether

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: sodium acetate; N-Bromosuccinimide / tetrahydrofuran; water / 2 h / 20 °C
1.2: 20 - 80 °C
2.1: hydrogenchloride; water / tetrahydrofuran / 4 h / Reflux
3.1: 0.5 h / 100 °C
4.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7
5.1: pyridine / 2 h / 0 - 20 °C
6.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
7.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
8.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
9.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
10.1: hydrogenchloride / water / 0.25 h / 0 °C
10.2: 3 h / 0 °C
View Scheme
2-amino-6-(ethylenedioxy)-4,5,6,7-tetrahydrobenzothiazole
159015-33-5

2-amino-6-(ethylenedioxy)-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: hydrogenchloride; water / tetrahydrofuran / 4 h / Reflux
2.1: 0.5 h / 100 °C
3.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7
4.1: pyridine / 2 h / 0 - 20 °C
5.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
6.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
7.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
8.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
9.1: hydrogenchloride / water / 0.25 h / 0 °C
9.2: 3 h / 0 °C
View Scheme
2-Acetylamino-6-oxo-4,5,6,7-tetrahydrobenzothiazole
404892-23-5

2-Acetylamino-6-oxo-4,5,6,7-tetrahydrobenzothiazole

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: Sucrose / aq. phosphate buffer; n-heptane / 16 h / 30 °C / pH 7
2.1: pyridine / 2 h / 0 - 20 °C
3.1: sodium azide / N,N-dimethyl-formamide / 6 h / 20 - 70 °C / Inert atmosphere
4.1: polymer bonded triphenyl phosphine / tetrahydrofuran; water / 12 h / 40 °C
5.1: hydrogenchloride; water / tetrahydrofuran / 12 h / 80 °C
6.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
7.1: hydrogenchloride / water / 0.25 h / 0 °C
7.2: 3 h / 0 °C
View Scheme
pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

pramipexole
104632-26-0

pramipexole

Conditions
ConditionsYield
With potassium hydroxide In water at 20℃; for 1 - 2h; Product distribution / selectivity;86%
With sodium hydroxide In water
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

trifluoroacetic acid
76-05-1

trifluoroacetic acid

pramipexole(boc) trifluoroacetate

pramipexole(boc) trifluoroacetate

Conditions
ConditionsYield
Stage #1: di-tert-butyl dicarbonate; pramipexole dihydrochloride With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 20℃; for 3h;
Stage #2: trifluoroacetic acid In water
422 mg
BOC-glycine
4530-20-5

BOC-glycine

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

2ClH*C12H20N4OS

2ClH*C12H20N4OS

Conditions
ConditionsYield
Stage #1: BOC-glycine; pramipexole dihydrochloride With 4-methyl-morpholine; (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate In dimethyl sulfoxide for 1h;
Stage #2: With hydrogenchloride In methanol; water for 4h;
490 mg
BOC-glycine
4530-20-5

BOC-glycine

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

trifluoroacetic acid
76-05-1

trifluoroacetic acid

C17H28N4O3S*C2HF3O2

C17H28N4O3S*C2HF3O2

Conditions
ConditionsYield
Stage #1: BOC-glycine; pramipexole dihydrochloride With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dimethyl sulfoxide for 1h;
Stage #2: trifluoroacetic acid In water
721 mg
C25H25NO3S

C25H25NO3S

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

trifluoroacetic acid
76-05-1

trifluoroacetic acid

C35H40N4O2S2*C2HF3O2

C35H40N4O2S2*C2HF3O2

Conditions
ConditionsYield
Stage #1: C25H25NO3S; pramipexole dihydrochloride With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dimethyl sulfoxide for 16h;
Stage #2: trifluoroacetic acid In water; acetonitrile
21 mg
C34H42N2O5S

C34H42N2O5S

pramipexole dihydrochloride
104632-25-9

pramipexole dihydrochloride

trifluoroacetic acid
76-05-1

trifluoroacetic acid

C44H57N5O4S2*C2HF3O2

C44H57N5O4S2*C2HF3O2

Conditions
ConditionsYield
Stage #1: C34H42N2O5S; pramipexole dihydrochloride With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In dimethyl sulfoxide for 0.666667h;
Stage #2: trifluoroacetic acid In water; acetonitrile
38 mg

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View