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SICHUAN TONGSHENG AMINOACID CO.LTD

Sichuan Tongsheng is the most strongest manufacturer and exporter of amino acids and their derivatives in China, we have the best quality and price. Guarantee high quality, competive price and reliable service. We fully compliance with ISO9001:2008,

Boc-Glycine

Cas:4530-20-5

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Boc-Glycine Manufacturer/High quality/Best price/In stock

Cas:4530-20-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up Boc-Gly-OH N-(tert-Butoxycarbonyl)glycine Boc-Glycine 4530-20-5

Cas:4530-20-5

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Boc-Gly-OH supplier in China

Cas:4530-20-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity Various Specifications BOC-Glycine CAS:4530-20-5

Cas:4530-20-5

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Manufacturer supply BOC-Glycine CAS 4530-20-5 with attractive price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed a

Manufacturer supply BOC-Glycine CAS 4530-20-5 with attractive price

Cas:4530-20-5

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. After many years of efforts, we have established stable

Boc-l-glycine

Cas:4530-20-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

BOC-Glycine

Cas:4530-20-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply N-(tert-butoxycarbonyl)glycine

Cas:4530-20-5

Min.Order:1

Negotiable

Type:Other

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality BOC-Glycine

Cas:4530-20-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-tert-Butoxycarbonylglycine

Cas:4530-20-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

BOC-Glycine 4530-20-5 BOC-Glycine Basic information Product Name: BOC-Glycine Synonyms: BOC-GLYCINE-OH;BOC-GLY;BOC-GLYCINE;BOC-GLY-OH;BOC-L-GLY;BOC-AMINOXYACETIC ACID;N-T-BOC-GLYCINE;N

BOC-Glycine 4530-20-5

Cas:4530-20-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Competitve Price in stockCAS 4530-20-5 with fast shipping

Cas:4530-20-5

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Boc-Glycine/ LIDE PHARMA- Factory supply / Best price

Cas:4530-20-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product name BOC-Glycine Alias N-(tert-Butoxycarbonyl)glycine; N-Boc-glycine; Boc-Gly-OH~N-(tert-Butoxycarbonyl)glycine; NtertButoxycarbonylglycine; Boc-Gly-OH; [(tert-butoxycarbonyl)amino]acetate;

BOC-Glycine

Cas:4530-20-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 4530-20-5 BOC-Glycine

Cas:4530-20-5

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Boc-Glycine 4530-20-5

Cas:4530-20-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

BOC-Glycine

Cas:4530-20-5

Min.Order:1 Kilogram

FOB Price: $75.0 / 100.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

BOC-Glycine CAS:4530-20-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

BOC-Glycine CAS:4530-20-5

Cas:4530-20-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Boc-Glycine

Cas:4530-20-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Boc-Glycine

Cas:4530-20-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

BOC-Glycine

Cas:4530-20-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

BOC-Glycine

Cas:4530-20-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

BOC-Glycine-OH

Cas:4530-20-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

BOC-GLYCINE

Cas:4530-20-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

4-Pyridineethanol

Cas:4530-20-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

BOC-Glycine

Cas:4530-20-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Boc-Gly-OH

Cas:4530-20-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

High purity BOC-Gly-OH 4530-20-5 in stock immediately delivery good supplierAppearance:Powder Storage:Dry and ventilated Package:according to customers' requirements Application:APIs Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(

HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery Appearance:White To Off-White Powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Used in the composition

BOC-Glycine

Cas:4530-20-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With potassium hydroxide In 1,4-dioxane; water at 20℃; for 12h;100%
Stage #1: glycine With sodium hydroxide In 1,4-dioxane; water at 0℃; for 0.25h;
Stage #2: di-tert-butyl dicarbonate In 1,4-dioxane; water at 0 - 20℃;
100%
With sodium hydroxide In 1,4-dioxane100%
2-oxo-2-phenylethyl 2-(tert-butoxycarbonylamino)acetate
83316-95-4

2-oxo-2-phenylethyl 2-(tert-butoxycarbonylamino)acetate

A

BOC-glycine
4530-20-5

BOC-glycine

B

acetophenone
98-86-2

acetophenone

Conditions
ConditionsYield
With N,N,N',N'-tetramethyl-o-phenylenediamine In acetonitrile for 2h; Irradiation;A 100%
B n/a
tert-butoxycarbonylamino-acetic acid 4-tert-butyl-benzyl ester

tert-butoxycarbonylamino-acetic acid 4-tert-butyl-benzyl ester

A

BOC-glycine
4530-20-5

BOC-glycine

B

4-tert-butyltoluene
98-51-1

4-tert-butyltoluene

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal for 3h;A 100%
B n/a
(1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl (tert-butoxycarbonyl)glycinate

(1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl (tert-butoxycarbonyl)glycinate

A

BOC-glycine
4530-20-5

BOC-glycine

B

C16H10O3S
1033736-87-6

C16H10O3S

Conditions
ConditionsYield
In chloroform-d1 for 0.25h; Solvent; Photolysis; Inert atmosphere;A 97%
B n/a
glycine
56-40-6

glycine

BOC derivative

BOC derivative

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 20℃; for 8h;95%
tert-butyl (2,4-dioxo-3-azaspiro[5,5]undecan-3-yl) carbonate

tert-butyl (2,4-dioxo-3-azaspiro[5,5]undecan-3-yl) carbonate

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With sodium hydroxide In water; acetone at 25℃; for 12h;94%
(N-hydroxy-5-norbornene-2,3-diformylimino)tert-butyl ester
64205-15-8

(N-hydroxy-5-norbornene-2,3-diformylimino)tert-butyl ester

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With tertiary amine In 1,4-dioxane; water for 3h;85%
tert-butyl 4,6-dimethoxy-1,3,5-triazinyl carbonate
909114-65-4

tert-butyl 4,6-dimethoxy-1,3,5-triazinyl carbonate

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With triethylamine In methanol at 20℃; for 0.5h;85%
4-nitrobenzyl N-(tert-butoxycarbonyl)glycinate
79113-14-7

4-nitrobenzyl N-(tert-butoxycarbonyl)glycinate

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With sodium dithionite; sodium carbonate In acetonitrile80%
glycine
56-40-6

glycine

1-tert-butoxycarbonyloxybenzotriazole
89037-64-9

1-tert-butoxycarbonyloxybenzotriazole

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water for 0.166667h; Ambient temperature;80%
2-oxo-2-phenylethyl 2-(tert-butoxycarbonylamino)acetate
83316-95-4

2-oxo-2-phenylethyl 2-(tert-butoxycarbonylamino)acetate

A

BOC-glycine
4530-20-5

BOC-glycine

B

(tert-butoxycarbonyl)glycine hydrazide
6926-09-6

(tert-butoxycarbonyl)glycine hydrazide

Conditions
ConditionsYield
With hydrazine hydrate In methanol Product distribution;A 75%
B 12%
N-Boc-glycine 2-(2-acetylphenyl)-1-methylethyl ester
618068-89-6

N-Boc-glycine 2-(2-acetylphenyl)-1-methylethyl ester

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
In acetonitrile for 3h; Photolysis;73%
(E)-3-methoxyallyl 2-((tert-butoxycarbonyl)amino)acetate
1080004-01-8

(E)-3-methoxyallyl 2-((tert-butoxycarbonyl)amino)acetate

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With zinc(II) chloride; lithium hexamethyldisilazane In tetrahydrofuran at -78 - 20℃; Inert atmosphere;59%
With potassium hexamethylsilazane; zinc(II) chloride In tetrahydrofuran at -78 - 20℃; Inert atmosphere;54%
tert-Butoxycarbonylamino-acetic acid (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl ester
42721-06-2

tert-Butoxycarbonylamino-acetic acid (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl ester

glycine ethyl ester hydrochloride
5680-79-5

glycine ethyl ester hydrochloride

A

BOC-glycine
4530-20-5

BOC-glycine

B

N-tert-butoxycarbonyl glycyl glycine methyl ester
53487-98-2

N-tert-butoxycarbonyl glycyl glycine methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine In N,N-dimethyl-formamide at 38℃; for 96h;A n/a
B 57%
glycine ethyl ester hydrochloride
5680-79-5

glycine ethyl ester hydrochloride

2,3,4,6-tetra-O-benzyl-1-O-(N-tert-butoxycarbonyl-glycyl)-β-D-glucopyranose
35909-78-5

2,3,4,6-tetra-O-benzyl-1-O-(N-tert-butoxycarbonyl-glycyl)-β-D-glucopyranose

A

BOC-glycine
4530-20-5

BOC-glycine

B

N-tert-butoxycarbonyl glycyl glycine methyl ester
53487-98-2

N-tert-butoxycarbonyl glycyl glycine methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine In N,N-dimethyl-formamide at 38℃; for 96h;A n/a
B 55%
C n/a
t-butyl malonate
541-16-2

t-butyl malonate

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With sodium carbonate In water; acetonitrile at -5 - 20℃;35%
Glycine tert-butyl ester
6456-74-2

Glycine tert-butyl ester

2-oxo-2-phenylethyl 2-(tert-butoxycarbonylamino)acetate
83316-95-4

2-oxo-2-phenylethyl 2-(tert-butoxycarbonylamino)acetate

A

BOC-glycine
4530-20-5

BOC-glycine

B

Boc-glycylglycine tert-butyl ester
5845-68-1

Boc-glycylglycine tert-butyl ester

Conditions
ConditionsYield
In ethyl acetate for 24h; Product distribution; Ambient temperature;A 10%
B 30%
tert-Butyl 4-nitrophenyl carbonate
13303-10-1

tert-Butyl 4-nitrophenyl carbonate

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With sodium hydroxide; tert-butyl alcohol
phosgene
75-44-5

phosgene

GlyOEt*HCl
459-73-4

GlyOEt*HCl

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With toluene Erwaermen des Reaktionsprodukts mit tert-Butylalkohol und anschliessenden Hydrolyse;
tert-butyl alcohol
75-65-0

tert-butyl alcohol

Glycine ethyl ester isocyanate
2949-22-6

Glycine ethyl ester isocyanate

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With triethylamine Behandeln des Reaktionsprodukts mit wss.NaOH und Dioxan;
tert-butyl chloroformate
24608-52-4

tert-butyl chloroformate

glycine
56-40-6

glycine

BOC-glycine
4530-20-5

BOC-glycine

Conditions
ConditionsYield
With sodium hydroxide
BOC-glycine
4530-20-5

BOC-glycine

benzylamine
100-46-9

benzylamine

Boc-glycine-benzylamide
19811-52-0

Boc-glycine-benzylamide

Conditions
ConditionsYield
Stage #1: BOC-glycine; benzylamine With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 0.0166667h;
Stage #2: With HATU for 18h;
100%
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;99%
With zirconium(IV) chloride In tetrahydrofuran at 70℃; for 24h; Molecular sieve; Inert atmosphere;99%
BOC-glycine
4530-20-5

BOC-glycine

methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride
27894-50-4

methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride

Nα-tert-butoxycarbonylglycyl-Nε-benzyloxycarbonyl-L-lysine methyl ester
32689-62-6

Nα-tert-butoxycarbonylglycyl-Nε-benzyloxycarbonyl-L-lysine methyl ester

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at -20 - 20℃; for 4h; Acylation;100%
Stage #1: BOC-glycine With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 0.5h; Cooling with ice;
Stage #2: methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;
92.2%
(i) Et3N, ClCO2iBu, (ii) /BRN= 3578476/, Et3N; Multistep reaction;
With 4-methyl-morpholine; triethylamine; isobutyl chloroformate 1) THF, -10 deg C, 15 min, 2) THF, 12 h; Yield given. Multistep reaction;
BOC-glycine
4530-20-5

BOC-glycine

L-alanine benzyl ester p-toluenesulfonate
42854-62-6

L-alanine benzyl ester p-toluenesulfonate

Boc-Gly-Ala-OBzl
63649-08-1

Boc-Gly-Ala-OBzl

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine100%
With TEA; diphenyl phosphoryl azide In N,N-dimethyl-formamide 1.) 0 deg C, 4 h; 2.) r.t., overnight;85%
Stage #1: BOC-glycine; L-alanine benzyl ester p-toluenesulfonate With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 0.166667h; Inert atmosphere;
Stage #2: With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;
BOC-glycine
4530-20-5

BOC-glycine

benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride
16652-71-4

benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride

(S)-1-(2-tert-butoxycarbonylaminoacetyl)pyrrolidine-2-carboxylic acid benzyl ester
29776-78-1

(S)-1-(2-tert-butoxycarbonylaminoacetyl)pyrrolidine-2-carboxylic acid benzyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; triethylamine In chloroform100%
With benzotriazol-1-ol; triethylamine In chloroform100%
With benzotriazol-1-ol; triethylamine In chloroform100%
BOC-glycine
4530-20-5

BOC-glycine

L-valine benzyl ester p-toluenesulfonate salt
16652-76-9

L-valine benzyl ester p-toluenesulfonate salt

N-t-butoxycarbonylglycyl-L-valine benzyl ester
66415-00-7

N-t-butoxycarbonylglycyl-L-valine benzyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine100%
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 0 - 20℃; for 12h; Inert atmosphere;94%
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide 1.) 0 deg C, 2.) overnight, 4 deg C;89%
With 4-methyl-morpholine; isobutyl chloroformate 1.) THF, -15 deg C, 2.) DMF, a) -15 deg C, 30 min, b) r.t., 30 min.; Yield given. Multistep reaction;
BOC-glycine
4530-20-5

BOC-glycine

(-)-8-phenylmenthol
65253-04-5

(-)-8-phenylmenthol

(1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate
117681-86-4

(1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 13h;100%
Stage #1: BOC-glycine With dmap; dicyclohexyl-carbodiimide In dichloromethane at -30℃; for 0.166667h;
Stage #2: (-)-8-phenylmenthol In dichloromethane for 20h; Heating;
96%
With dmap; dicyclohexyl-carbodiimide93%
BOC-glycine
4530-20-5

BOC-glycine

2-(N-tert-butoxycarbonylamino)ethanol
26690-80-2

2-(N-tert-butoxycarbonylamino)ethanol

Conditions
ConditionsYield
Stage #1: BOC-glycine With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at -15℃; for 0.25h;
Stage #2: With sodium tetrahydroborate In tetrahydrofuran; water at -15℃; for 1h;
100%
With diisopropoxytitanium(III) tetrahydroborate In dichloromethane for 4h; Ambient temperature;88%
With sodium bis(2-methoxyethoxy)aluminium dihydride In tetrahydrofuran; toluene at 0℃; for 2h;77.1%
BOC-glycine
4530-20-5

BOC-glycine

benzyl bromide
100-39-0

benzyl bromide

tert-butoxycarbonylamino-acetic acid benzyl ester
54244-69-8

tert-butoxycarbonylamino-acetic acid benzyl ester

Conditions
ConditionsYield
Stage #1: BOC-glycine With caesium carbonate In methanol pH=7;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 20℃; for 5h; Further stages.;
100%
Stage #1: BOC-glycine With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 0℃; for 18h; Further stages;
100%
With triethylamine In N,N-dimethyl-formamide at 25℃; for 5h;54%
With caesium carbonate 1) MeOH, water, pH 7.0, 2) DMF, 5 h; Yield given. Multistep reaction;
With sodium iodide In acetone for 2h; Reflux; Inert atmosphere;
BOC-glycine
4530-20-5

BOC-glycine

ethyl iodide
75-03-6

ethyl iodide

N-(tert-buytoxycarbonyl)-N-ethylglycine
149794-10-5

N-(tert-buytoxycarbonyl)-N-ethylglycine

Conditions
ConditionsYield
Stage #1: BOC-glycine; ethyl iodide With sodium hydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: In tetrahydrofuran at 0℃;
100%
Stage #1: BOC-glycine; ethyl iodide With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: With citric acid In water pH=2 - 3;
100%
Stage #1: BOC-glycine; ethyl iodide With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: With citric acid In water pH=2 - 3;
100%
BOC-glycine
4530-20-5

BOC-glycine

allyl bromide
106-95-6

allyl bromide

allyl 2-(tert-butoxycarbonylamino)acetate
124373-83-7

allyl 2-(tert-butoxycarbonylamino)acetate

Conditions
ConditionsYield
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 50℃; for 16h;100%
With N-ethyl-N,N-diisopropylamine for 0.666667h; Reflux;91%
With caesium carbonate In acetonitrile90%
BOC-glycine
4530-20-5

BOC-glycine

aniline
62-53-3

aniline

N-glycyl>aniline
27904-92-3

N-glycyl>aniline

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In tetrahydrofuran at 25℃; for 5h;100%
With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 5h;99%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 20℃; for 6h;96.9%
BOC-glycine
4530-20-5

BOC-glycine

isobutyl chloroformate
543-27-1

isobutyl chloroformate

N-(t-butoxycarbonyl)glycyl i-butyl carbonate
66866-43-1

N-(t-butoxycarbonyl)glycyl i-butyl carbonate

Conditions
ConditionsYield
With 4-methyl-morpholine In tetrahydrofuran at -15℃; for 0.0833333h;100%
With 4-methyl-morpholine In tetrahydrofuran at -20℃; for 0.05h;
BOC-glycine
4530-20-5

BOC-glycine

tetrakis-5,10,15,20-(o-aminophenyl)porphyrin
52199-35-6

tetrakis-5,10,15,20-(o-aminophenyl)porphyrin

α,α,α,α-5,10,15,20-tetrakis-(2-(N-[(2-t-butylcarbamoyl)ethanamide]phenyl))porphyrin

α,α,α,α-5,10,15,20-tetrakis-(2-(N-[(2-t-butylcarbamoyl)ethanamide]phenyl))porphyrin

Conditions
ConditionsYield
With 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at -5 - 20℃; for 50h; Condensation;100%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane Inert atmosphere; Cooling with ice;62%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane
BOC-glycine
4530-20-5

BOC-glycine

H-Ala-Glu(OBzl)-OBzl hydrochloride

H-Ala-Glu(OBzl)-OBzl hydrochloride

Boc-Gly-Ala-Glu(OBzl)-OBzl
125274-43-3

Boc-Gly-Ala-Glu(OBzl)-OBzl

Conditions
ConditionsYield
Stage #1: H-Ala-Glu(OBzl)-OBzl hydrochloride With triethylamine In dichloromethane Hydrolysis;
Stage #2: BOC-glycine With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane at 0 - 25℃; for 14h; Condensation;
100%
BOC-glycine
4530-20-5

BOC-glycine

phenethylamine
64-04-0

phenethylamine

tert-butyl N-{[(2-phenylethyl)carbamoyl]methyl}carbamate
613675-75-5

tert-butyl N-{[(2-phenylethyl)carbamoyl]methyl}carbamate

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In acetonitrile at 0 - 20℃; Acylation;100%
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In ethyl acetate at 20℃; for 72h;94%
Stage #1: BOC-glycine With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 1h;
Stage #2: phenethylamine In dichloromethane for 16h;
81%
Stage #1: BOC-glycine With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: phenethylamine In N,N-dimethyl-formamide at 20℃;
72%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 23℃; for 4h; Inert atmosphere;71%
1-aza-18-crown-6
33941-15-0

1-aza-18-crown-6

BOC-glycine
4530-20-5

BOC-glycine

[2-oxo-2-(1,4,7,10,13-pentaoxa-16-aza-cyclooctadec-16-yl)-ethyl]-carbamic acid tert-butyl ester
394208-14-1

[2-oxo-2-(1,4,7,10,13-pentaoxa-16-aza-cyclooctadec-16-yl)-ethyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With bis(trichloromethyl) carbonate; lutidine In tetrahydrofuran at 25 - 50℃; for 2h;100%
With 2,6-dimethylpyridine; bis(trichloromethyl) carbonate In tetrahydrofuran Inert atmosphere;
BOC-glycine
4530-20-5

BOC-glycine

4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}benzyl alcohol
172611-73-3

4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}benzyl alcohol

tert-butoxycarbonylamino-acetic acid 4-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butylamino]-benzyl ester

tert-butoxycarbonylamino-acetic acid 4-[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butylamino]-benzyl ester

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 24h;100%
BOC-glycine
4530-20-5

BOC-glycine

4,6-O-di(tert-butyl)silanediyl-D-glucal
191593-14-3

4,6-O-di(tert-butyl)silanediyl-D-glucal

3-O-(N-tert-butoxycarbonyl-2'-amino-ethanoyl)-4,6-O-di-tert-butylsilanediyl-D-glucal
848359-00-2

3-O-(N-tert-butoxycarbonyl-2'-amino-ethanoyl)-4,6-O-di-tert-butylsilanediyl-D-glucal

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane100%
BOC-glycine
4530-20-5

BOC-glycine

Propargylamine
2450-71-7

Propargylamine

tert-butyl (2-oxo-2-(prop-2-yn-1-ylamino)ethyl)carbamate
847490-49-7

tert-butyl (2-oxo-2-(prop-2-yn-1-ylamino)ethyl)carbamate

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 6h; Inert atmosphere;100%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h; Inert atmosphere;99%
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In acetonitrile at 20℃;96%
BOC-glycine
4530-20-5

BOC-glycine

anthranilic acid
118-92-3

anthranilic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

2-aminomethyl-3-(2-methoxyethyl)-3H-quinazolin-4-one

2-aminomethyl-3-(2-methoxyethyl)-3H-quinazolin-4-one

Conditions
ConditionsYield
Stage #1: BOC-glycine; anthranilic acid With pyridine; triphenyl phosphite at 150℃; for 0.166667h; microwave irradiation;
Stage #2: 2-methoxyethylamine at 220℃; for 0.0666667h; microwave irradiation;
100%
BOC-glycine
4530-20-5

BOC-glycine

anthranilic acid
118-92-3

anthranilic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

[3-(2-methoxyethyl)-4-oxo-3,4-dihydroquinazolin-2-yl-methyl]carbamic acid tert-butyl ester

[3-(2-methoxyethyl)-4-oxo-3,4-dihydroquinazolin-2-yl-methyl]carbamic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: BOC-glycine; anthranilic acid With pyridine; triphenyl phosphite at 150℃; for 0.166667h; microwave irradiation;
Stage #2: 2-methoxyethylamine at 180℃; for 0.05h; microwave irradiation;
100%
(3S,10R,16S)-16-{(1R)-3-[4-(hydroxymethyl)phenyl]-1-methylallyl}-3-isobutyl-10-(4-methoxybenzyl)-1-oxa-4,8,11-triazacyclohexadec-13-ene-2,5,9,12-tetraone
916452-54-5

(3S,10R,16S)-16-{(1R)-3-[4-(hydroxymethyl)phenyl]-1-methylallyl}-3-isobutyl-10-(4-methoxybenzyl)-1-oxa-4,8,11-triazacyclohexadec-13-ene-2,5,9,12-tetraone

BOC-glycine
4530-20-5

BOC-glycine

tert-butoxycarbonylamino-acetic acid 4-{3-[3-isobutyl-10-(4-methoxy-benzyl)-2,5,9,12-tetraoxo-1-oxa-4,8,11-triaza-cyclohexadec-13-en-16-yl]-but-1-enyl}-benzyl ester
916452-55-6

tert-butoxycarbonylamino-acetic acid 4-{3-[3-isobutyl-10-(4-methoxy-benzyl)-2,5,9,12-tetraoxo-1-oxa-4,8,11-triaza-cyclohexadec-13-en-16-yl]-but-1-enyl}-benzyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 3h;100%
BOC-glycine
4530-20-5

BOC-glycine

trans-7-chloro-2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepin-1-amine

trans-7-chloro-2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepin-1-amine

[[[(trans-7-chloro-2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepin-1-yl)amino]carbonyl]methyl]carbamic acid 1,1-dimethylethyl ester

[[[(trans-7-chloro-2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepin-1-yl)amino]carbonyl]methyl]carbamic acid 1,1-dimethylethyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane for 3h; pH=9;100%
BOC-glycine
4530-20-5

BOC-glycine

2-(N-t-butoxycarbonylamino)thioacetamide
89226-13-1

2-(N-t-butoxycarbonylamino)thioacetamide

Conditions
ConditionsYield
With Lawessons reagent In dichloromethane at 25℃; for 16h;100%
Stage #1: BOC-glycine With ammonium hydroxide; triethylamine; isobutyl chloroformate In tetrahydrofuran
Stage #2: With tetraphosphorus decasulfide; sodium carbonate In tetrahydrofuran
83%
Multi-step reaction with 3 steps
1: Et3N / tetrahydrofuran / 0.42 h / -10 °C
2: aq. MH3 / tetrahydrofuran / 0.75 h / -10 °C
3: 85 percent / Lawesson's reagent / CH2Cl2 / 16 h / Ambient temperature
View Scheme
BOC-glycine
4530-20-5

BOC-glycine

p-aminoiodobenzene
540-37-4

p-aminoiodobenzene

[(4-iodophenylcarbamoyl)methyl]carbamic acid tert-butyl ester
216774-64-0

[(4-iodophenylcarbamoyl)methyl]carbamic acid tert-butyl ester

Conditions
ConditionsYield
With dacarbazine; dmap In dichloromethane100%
With dmap; diisopropyl-carbodiimide In dichloromethane for 20h; Inert atmosphere;100%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 5h;98%
BOC-glycine
4530-20-5

BOC-glycine

bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride
68641-49-6

bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride

(R*)-N-[[2-[N-[(1,1-Dimethylethoxy)carbonyl]glycyl]-1,2,3,4-tetrahydro-3-isoquinolinyl]carbonyl]-L-methionine

(R*)-N-[[2-[N-[(1,1-Dimethylethoxy)carbonyl]glycyl]-1,2,3,4-tetrahydro-3-isoquinolinyl]carbonyl]-L-methionine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane100%
BOC-glycine
4530-20-5

BOC-glycine

N,N-didodecylamine
3007-31-6

N,N-didodecylamine

C31H62N2O3
879004-97-4

C31H62N2O3

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 5h;100%

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