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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. As a leading manufacturer and supplier of chemicals in China, Day

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(1S,2R,3S,5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)-methyl]-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 110567-22-1 with competitive price

Cas:110567-22-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name Entecavir Intermediate CAS NO. 110567-22-1 Purity 99% Storage condi

1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane CAS:110567-22-1

Cas:110567-22-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool & dr

Entecavir Intermediate CAS:110567-22-1

Cas:110567-22-1

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane 110567-22-1

Cas:110567-22-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane CAS:110567-22-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of ch

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane CAS:110567-22-1

Cas:110567-22-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(1S,2R,3S,5R)-3-(Benzyloxymethyl)-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Entecavir Intermediate

Cas:110567-22-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(1S,2R,3S,5R)-3-(Benzyloxy)-2-((benzyloxy)methyl)-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l A

2-Isopropyl-1,3-thiazole-4-carboxylic acid

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hebei Lead Bio-Chemicals Co., Ltd.

Hebei Lead Bio-Chemicals Co., Ltd. established in 2006, devolved in resurching, manufacturing and supplying of pharmaceuticals,food ingredients, cosmetics,health care products, Chinese herb, plant extracts and some fine chemicals,is one of leading gr

The China supplier of Entecavir Intermediate Cas:110567-22-1

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

(1S,2R,3S,5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Hubei Vanz Pharm Co.,Ltd

ISO Factory/Good qualityAppearance:off white Storage:dry and cool place Package:10G/BAG; 1KG/BAG ;25KG/DRUM Application:Active pharaceutical ingredients Transportation:BY SEA,AIR,EXPRESS Port:SHANGHAI;BEIJING

Ente-3

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(1S, 2R, 3S, 5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(1S,2R,3S,5R)-3-(Benzyloxy)-2-((benzyloxy)Methyl)-6-oxabicyclo[3.1.0]hexane

Cas:110567-22-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Synthetic route

benzyl bromide
100-39-0

benzyl bromide

(2R,3S)-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexan-3-ol
117641-39-1

(2R,3S)-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexan-3-ol

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Stage #1: (2R,3S)-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexan-3-ol With sodium hydride In tetrahydrofuran at 20℃; for 1h;
Stage #2: benzyl bromide With tetra-(n-butyl)ammonium iodide In tetrahydrofuran at 20℃; for 12h;
86%
With tetra-(n-butyl)ammonium iodide; sodium hydride 1.) THF, 2 h; 1.) THF, 2.5 h; Yield given. Multistep reaction;
With tetra-(n-butyl)ammonium iodide; sodium hydride In N,N-dimethyl-formamide Yield given;
With tetra-(n-butyl)ammonium iodide; sodium hydride In N,N-dimethyl-formamide; mineral oil at -50℃; for 18h;
With sodium hydride In tetrahydrofuran; water at 20℃; Large scale;4.4 kg
Benzyloxymethyl chloride
3587-60-8

Benzyloxymethyl chloride

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: NaH / tetrahydrofuran / 1 h / 0 °C
1.2: tetrahydrofuran / 2 h / -40 °C
2.1: (-)-diisopinocamphenylborane / tetrahydrofuran / 17 h / -60 - 0 °C
2.2: 8.20 g / aq. NaOH; H2O2 / diethyl ether; tetrahydrofuran / 12 h / 0 °C
3.1: 82 percent / Mo(CO)6; t-BuOOH / benzene; decane / 3 h / 80 °C
4.1: NaH / tetrahydrofuran / 1 h / 20 °C
4.2: 86 percent / tetrabutylammonium iodide / tetrahydrofuran / 12 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: tetrahydrofuran / -78 - -65 °C
2: 1.) diisopinylcampheylborane (prepared from (+)-α-pinene), 2.) aq. NaOH, H2O2 / 1.) THF, -65 to -78 deg C
3: VO(acac)2, t-BuOOH / CH2Cl2
4: NaH, Bu4NI / dimethylformamide
View Scheme
Multi-step reaction with 4 steps
1: 1.) Na / 1.) THF, -5 deg C, 1.5 h; 2.) THF, -45 deg C, 1 h
2: 15.8 g / (-)-diisopinan-3-ylborane / tetrahydrofuran / 1.) -60 deg C, 1 h; 2.) 5 deg C, 18 h
3: 12.0 g / t-butyl hydroperoxide, vanadium(V)acetylacetonate / 1,2-dichloro-ethane / 2.75 h / 30 °C
4: 1.) NaH; 2.) tetrabutylammonium iodide / 1.) THF, 2 h; 1.) THF, 2.5 h
View Scheme
5-(benzyloxymethyl)cyclopentadiene
39939-07-6

5-(benzyloxymethyl)cyclopentadiene

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: (-)-diisopinocamphenylborane / tetrahydrofuran / 17 h / -60 - 0 °C
1.2: 8.20 g / aq. NaOH; H2O2 / diethyl ether; tetrahydrofuran / 12 h / 0 °C
2.1: 82 percent / Mo(CO)6; t-BuOOH / benzene; decane / 3 h / 80 °C
3.1: NaH / tetrahydrofuran / 1 h / 20 °C
3.2: 86 percent / tetrabutylammonium iodide / tetrahydrofuran / 12 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 1.) diisopinylcampheylborane (prepared from (+)-α-pinene), 2.) aq. NaOH, H2O2 / 1.) THF, -65 to -78 deg C
2: VO(acac)2, t-BuOOH / CH2Cl2
3: NaH, Bu4NI / dimethylformamide
View Scheme
Multi-step reaction with 3 steps
1: 15.8 g / (-)-diisopinan-3-ylborane / tetrahydrofuran / 1.) -60 deg C, 1 h; 2.) 5 deg C, 18 h
2: 12.0 g / t-butyl hydroperoxide, vanadium(V)acetylacetonate / 1,2-dichloro-ethane / 2.75 h / 30 °C
3: 1.) NaH; 2.) tetrabutylammonium iodide / 1.) THF, 2 h; 1.) THF, 2.5 h
View Scheme
cyclopenta-1,3-diene
542-92-7

cyclopenta-1,3-diene

(AsCF3)4.5

(AsCF3)4.5

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: NaH / tetrahydrofuran / 1 h / 0 °C
1.2: tetrahydrofuran / 2 h / -40 °C
2.1: (-)-diisopinocamphenylborane / tetrahydrofuran / 17 h / -60 - 0 °C
2.2: 8.20 g / aq. NaOH; H2O2 / diethyl ether; tetrahydrofuran / 12 h / 0 °C
3.1: 82 percent / Mo(CO)6; t-BuOOH / benzene; decane / 3 h / 80 °C
4.1: NaH / tetrahydrofuran / 1 h / 20 °C
4.2: 86 percent / tetrabutylammonium iodide / tetrahydrofuran / 12 h / 20 °C
View Scheme
(1S,2R)-2-(benzyloxymethyl)-1-hydroxy-3-cyclopentene
110567-21-0

(1S,2R)-2-(benzyloxymethyl)-1-hydroxy-3-cyclopentene

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 82 percent / Mo(CO)6; t-BuOOH / benzene; decane / 3 h / 80 °C
2.1: NaH / tetrahydrofuran / 1 h / 20 °C
2.2: 86 percent / tetrabutylammonium iodide / tetrahydrofuran / 12 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: VO(acac)2, t-BuOOH / CH2Cl2
2: NaH, Bu4NI / dimethylformamide
View Scheme
Multi-step reaction with 2 steps
1: 12.0 g / t-butyl hydroperoxide, vanadium(V)acetylacetonate / 1,2-dichloro-ethane / 2.75 h / 30 °C
2: 1.) NaH; 2.) tetrabutylammonium iodide / 1.) THF, 2 h; 1.) THF, 2.5 h
View Scheme
Multi-step reaction with 2 steps
1.1: tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium / dichloromethane / 16 h / 20 °C / Large scale
1.2: 1 h / 20 °C / Large scale
2.1: sodium hydride / water; tetrahydrofuran / 20 °C / Large scale
View Scheme
sodium cyclopentadienylide
4984-82-1

sodium cyclopentadienylide

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: tetrahydrofuran / -78 - -65 °C
2: 1.) diisopinylcampheylborane (prepared from (+)-α-pinene), 2.) aq. NaOH, H2O2 / 1.) THF, -65 to -78 deg C
3: VO(acac)2, t-BuOOH / CH2Cl2
4: NaH, Bu4NI / dimethylformamide
View Scheme
cyclopenta-1,3-diene
542-92-7

cyclopenta-1,3-diene

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) Na / 1.) THF, -5 deg C, 1.5 h; 2.) THF, -45 deg C, 1 h
2: 15.8 g / (-)-diisopinan-3-ylborane / tetrahydrofuran / 1.) -60 deg C, 1 h; 2.) 5 deg C, 18 h
3: 12.0 g / t-butyl hydroperoxide, vanadium(V)acetylacetonate / 1,2-dichloro-ethane / 2.75 h / 30 °C
4: 1.) NaH; 2.) tetrabutylammonium iodide / 1.) THF, 2 h; 1.) THF, 2.5 h
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(1S,2R,3S,5R)-2-Hydroxymethyl-6-oxa-bicyclo[3.1.0]hexan-3-ol
117641-42-6

(1S,2R,3S,5R)-2-Hydroxymethyl-6-oxa-bicyclo[3.1.0]hexan-3-ol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal100%
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(1S,2S,3S,5S)-5-azido-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
110567-23-2

(1S,2S,3S,5S)-5-azido-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

Conditions
ConditionsYield
With sodium azide; ammonium chloride In ethanol at 85℃; for 22h;99%
With sodium azide; ammonium chloride In ethanol at 85℃; for 22h;
C17H19N5O3
1351691-90-1

C17H19N5O3

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

C37H41N5O6

C37H41N5O6

Conditions
ConditionsYield
Stage #1: C17H19N5O3 With lithium hydride In N,N-dimethyl-formamide at 60℃; for 0.25h;
Stage #2: (2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane In N,N-dimethyl-formamide at 125℃; for 2.5h;
83%
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

potassium cyanide
151-50-8

potassium cyanide

(1S,2R,3R,4R)-1-Benzyloxy-2-benzyloxymethyl-4-cyano-3-hydroxycyclopentane
160860-62-8

(1S,2R,3R,4R)-1-Benzyloxy-2-benzyloxymethyl-4-cyano-3-hydroxycyclopentane

Conditions
ConditionsYield
With lithium perchlorate In acetonitrile at 70℃; for 96h;77.5%
With lithium perchlorate In acetonitrile at 70℃; for 24h;75%
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

2,4-dihydroxy-5-methylpyrimidine
65-71-4

2,4-dihydroxy-5-methylpyrimidine

1-(3',5'-di-O-benzyl-2'-deoxy-6'-hydroxy-6'-carba-β-D-ribofuranosyl)thymine
114071-49-7

1-(3',5'-di-O-benzyl-2'-deoxy-6'-hydroxy-6'-carba-β-D-ribofuranosyl)thymine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 140℃;70%
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

thymin
65-71-4

thymin

1-(3',5'-di-O-benzyl-2'-deoxy-6'-hydroxy-6'-carba-β-D-ribofuranosyl)thymine
114071-49-7

1-(3',5'-di-O-benzyl-2'-deoxy-6'-hydroxy-6'-carba-β-D-ribofuranosyl)thymine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 140℃;70%
With lithium hydride In N,N-dimethyl-formamide at 140℃;64%
Stage #1: thymin With triethylaluminum In tetrahydrofuran; hexane at 20℃; for 1h;
Stage #2: (2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane In tetrahydrofuran; hexane at 20℃; for 48h; ultrasound;
46%
In N-methyl-acetamide; methanol; dichloromethane; acetic acid; toluene; mineral oil
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

[1S-(1α,2β,3α,5β)]-5-(6-amino-9H-purin-9-yl)-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol
142217-96-7

[1S-(1α,2β,3α,5β)]-5-(6-amino-9H-purin-9-yl)-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol

Conditions
ConditionsYield
With lithium hydride In N,N-dimethyl-formamide at 120℃;70%
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

uracil
66-22-8

uracil

[1S-(1α,2β,3α,4β)]-1-[2-Hydroxy-4-(phenyl-methoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-2,4(1H,3H)-pyrimidinedione
114071-48-6

[1S-(1α,2β,3α,4β)]-1-[2-Hydroxy-4-(phenyl-methoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-2,4(1H,3H)-pyrimidinedione

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 130℃;65%
With sodium hydride In N,N-dimethyl-formamide at 140℃;63%
With acetic acid In N-methyl-acetamide; methanol; dichloromethane; mineral oil
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

2-Amino-6-benzyloxypurine
19916-73-5

2-Amino-6-benzyloxypurine

[1S-(1α,2β,3α,5β)]-5-(2-amino-6-benzyloxy-9H-purin-9-yl)-3-benzyloxy-2-(benzyloxy)methyl-cyclopentanol
142217-77-4

[1S-(1α,2β,3α,5β)]-5-(2-amino-6-benzyloxy-9H-purin-9-yl)-3-benzyloxy-2-(benzyloxy)methyl-cyclopentanol

Conditions
ConditionsYield
With lithium hydride In N,N-dimethyl-formamide at 125℃; for 2h;60%
Stage #1: 2-Amino-6-benzyloxypurine With lithium hydride In N,N-dimethyl-formamide at 20 - 60℃; for 0.416667h;
Stage #2: (2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane In N,N-dimethyl-formamide at 60 - 125℃; for 2.25h;
51.18%
With acetic acid In N-methyl-acetamide; methanol; ethanol; dichloromethane; chloroform
With tetrabutylammomium bromide; potassium hydroxide In toluene at 80℃; for 6h; Temperature; Reagent/catalyst;6 g
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

2-[(triphenylmethyl)amino]-6-benzyloxy-9H-purine

2-[(triphenylmethyl)amino]-6-benzyloxy-9H-purine

(1S,2S,3S,5S)-3-(benzyloxy)-5-[6-(benzyloxy)-2-[(triphenylmethyl)amino]-9H-purin-9-yl]-2-[(benzyloxy)methyl]cyclopentan-1-ol

(1S,2S,3S,5S)-3-(benzyloxy)-5-[6-(benzyloxy)-2-[(triphenylmethyl)amino]-9H-purin-9-yl]-2-[(benzyloxy)methyl]cyclopentan-1-ol

Conditions
ConditionsYield
Stage #1: 2-[(triphenylmethyl)amino]-6-benzyloxy-9H-purine With lithium hydride In N,N-dimethyl-formamide at 58 - 62℃; for 0.5h;
Stage #2: (2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane In N,N-dimethyl-formamide at 60 - 120℃; for 0.5h;
58.5%
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

2-amino-6-methoxyethoxypurine

2-amino-6-methoxyethoxypurine

(1S,2S,3S,5S)-5-[2-Amino-6-(2-methoxy-ethoxy)-purin-9-yl]-3-benzyloxy-2-benzyloxymethyl-cyclopentanol
114071-50-0

(1S,2S,3S,5S)-5-[2-Amino-6-(2-methoxy-ethoxy)-purin-9-yl]-3-benzyloxy-2-benzyloxymethyl-cyclopentanol

Conditions
ConditionsYield
lithium hydride In N,N-dimethyl-formamide at 145℃;
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

A

(1S,2S,3S,5S)-5-azido-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
110567-23-2

(1S,2S,3S,5S)-5-azido-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

B

(1R,2R,3R,4S)-2-Azido-4-benzyloxy-3-benzyloxymethyl-cyclopentanol

(1R,2R,3R,4S)-2-Azido-4-benzyloxy-3-benzyloxymethyl-cyclopentanol

Conditions
ConditionsYield
With sodium azide; ammonium chloride In ethanol; water for 22h; Heating;A 3.3 g
B 0.2 g
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

5'-O-[1-(2'-deoxy-6'-carba-β-D-ribofuranosyl)thymidinyl]monophosphate

5'-O-[1-(2'-deoxy-6'-carba-β-D-ribofuranosyl)thymidinyl]monophosphate

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: Et3Al / hexane; tetrahydrofuran / 1 h / 20 °C
1.2: 46 percent / hexane; tetrahydrofuran / 48 h / 20 °C / ultrasound
2.1: DMAP / acetonitrile / 16 h / 20 °C
3.1: 398 mg / AIBN; n-Bu3SnH / toluene / 3.5 h / 75 °C
4.1: 90 percent / BCl3 / CH2Cl2 / 5 h / -78 °C
5.1: i-Pr2NEt / acetonitrile; dimethylformamide / 2 h / -40 - 0 °C
6.1: 107 mg / t-BuOOH / acetonitrile; dimethylformamide / 2 h / -40 - 20 °C
7.1: 76 percent / Et3N; H2O / acetonitrile / 18 h / 20 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

1-((1R,3S,4R)-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-5-methylpyrimidine-2,4(1H,3H)-dione
114884-15-0

1-((1R,3S,4R)-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-5-methylpyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Et3Al / hexane; tetrahydrofuran / 1 h / 20 °C
1.2: 46 percent / hexane; tetrahydrofuran / 48 h / 20 °C / ultrasound
2.1: DMAP / acetonitrile / 16 h / 20 °C
3.1: 398 mg / AIBN; n-Bu3SnH / toluene / 3.5 h / 75 °C
4.1: 90 percent / BCl3 / CH2Cl2 / 5 h / -78 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

1-(3',5'-di-O-benzyl-2'-deoxy-6'-carba-β-D-ribofuranosyl)thymine
648414-58-8

1-(3',5'-di-O-benzyl-2'-deoxy-6'-carba-β-D-ribofuranosyl)thymine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: Et3Al / hexane; tetrahydrofuran / 1 h / 20 °C
1.2: 46 percent / hexane; tetrahydrofuran / 48 h / 20 °C / ultrasound
2.1: DMAP / acetonitrile / 16 h / 20 °C
3.1: 398 mg / AIBN; n-Bu3SnH / toluene / 3.5 h / 75 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

1-{(3S,1R,4R)-3-hydroxy-4-(8-methyl-2-oxo(4H-benzo[d]1,3,2-dioxaphosphan-2-yloxy)methylcyclopentyl)}-5-methyl-1,3-dihydropyrimidine-2,4(1H,3H)-dione

1-{(3S,1R,4R)-3-hydroxy-4-(8-methyl-2-oxo(4H-benzo[d]1,3,2-dioxaphosphan-2-yloxy)methylcyclopentyl)}-5-methyl-1,3-dihydropyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: Et3Al / hexane; tetrahydrofuran / 1 h / 20 °C
1.2: 46 percent / hexane; tetrahydrofuran / 48 h / 20 °C / ultrasound
2.1: DMAP / acetonitrile / 16 h / 20 °C
3.1: 398 mg / AIBN; n-Bu3SnH / toluene / 3.5 h / 75 °C
4.1: 90 percent / BCl3 / CH2Cl2 / 5 h / -78 °C
5.1: i-Pr2NEt / acetonitrile; dimethylformamide / 2 h / -40 - 0 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

3-methyl-cyclosaligenyl-5'-O-[1-(2'-deoxy-6'-carba-β-D-ribofuranosyl)thymidinyl]-phosphate
648414-62-4

3-methyl-cyclosaligenyl-5'-O-[1-(2'-deoxy-6'-carba-β-D-ribofuranosyl)thymidinyl]-phosphate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: Et3Al / hexane; tetrahydrofuran / 1 h / 20 °C
1.2: 46 percent / hexane; tetrahydrofuran / 48 h / 20 °C / ultrasound
2.1: DMAP / acetonitrile / 16 h / 20 °C
3.1: 398 mg / AIBN; n-Bu3SnH / toluene / 3.5 h / 75 °C
4.1: 90 percent / BCl3 / CH2Cl2 / 5 h / -78 °C
5.1: i-Pr2NEt / acetonitrile; dimethylformamide / 2 h / -40 - 0 °C
6.1: 107 mg / t-BuOOH / acetonitrile; dimethylformamide / 2 h / -40 - 20 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

thiocarbonic acid O-[3-benzyloxy-2-benzyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-cyclopentyl] ester O-phenyl ester

thiocarbonic acid O-[3-benzyloxy-2-benzyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-cyclopentyl] ester O-phenyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: Et3Al / hexane; tetrahydrofuran / 1 h / 20 °C
1.2: 46 percent / hexane; tetrahydrofuran / 48 h / 20 °C / ultrasound
2.1: DMAP / acetonitrile / 16 h / 20 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(S)-Methanocarba-Thymidine
156044-00-7

(S)-Methanocarba-Thymidine

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
3: 96.5 percent / CHCl3; diethyl ether / 72 h / 0 °C
4: benzophenone / benzene; acetonitrile / 2 h / Irradiation
5: 25percent aq. NaOH / methanol / 24 h / Heating
6: Et3N, DPPA / toluene / 1.) r.t., 2 h, 2.) 80 deg C, 2 h
7: toluene / 1.) 80 deg C, 2 h, 2.) r.t., overnight
8: 99 percent / Bu4NF / acetonitrile; tetrahydrofuran / 4 h / 70 °C
9: 85.5 percent / CH2Cl2 / 24 h / Ambient temperature
10: 2 M HCl / ethanol / 30 h / Heating
11: 87.72 percent / HCOOH / Pd / methanol / 2 h / 40 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethyl-1-aminobicyclo<3.1.0>hexane
170453-02-8

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethyl-1-aminobicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
3: 96.5 percent / CHCl3; diethyl ether / 72 h / 0 °C
4: benzophenone / benzene; acetonitrile / 2 h / Irradiation
5: 25percent aq. NaOH / methanol / 24 h / Heating
6: Et3N, DPPA / toluene / 1.) r.t., 2 h, 2.) 80 deg C, 2 h
7: toluene / 1.) 80 deg C, 2 h, 2.) r.t., overnight
8: 99 percent / Bu4NF / acetonitrile; tetrahydrofuran / 4 h / 70 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(3R,4S)-1-Cyano-4-benzyloxy-3-benzyloxymethylcyclopentene
170452-98-9

(3R,4S)-1-Cyano-4-benzyloxy-3-benzyloxymethylcyclopentene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethyl-1-cyanobicyclo<3.1.0>hexane
170453-00-6

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethyl-1-cyanobicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
3: 96.5 percent / CHCl3; diethyl ether / 72 h / 0 °C
4: benzophenone / benzene; acetonitrile / 2 h / Irradiation
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethylbicyclo<3.1.0>hexane-1-carboxylic acid
190195-74-5

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethylbicyclo<3.1.0>hexane-1-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
3: 96.5 percent / CHCl3; diethyl ether / 72 h / 0 °C
4: benzophenone / benzene; acetonitrile / 2 h / Irradiation
5: 25percent aq. NaOH / methanol / 24 h / Heating
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(3aR,4R,5S,6aR)-4-Benzyloxymethyl-5-benzyloxy-6a-cyano-3,3a,4,5,6,6a-hexahydrocyclopentapyrazole
170452-99-0

(3aR,4R,5S,6aR)-4-Benzyloxymethyl-5-benzyloxy-6a-cyano-3,3a,4,5,6,6a-hexahydrocyclopentapyrazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
3: 96.5 percent / CHCl3; diethyl ether / 72 h / 0 °C
View Scheme
(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane
110567-22-1

(2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethyl-1-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)bicyclo<3.1.0>hexane
190195-79-0

(1S,3S,4R,5S)-3-Benzyloxy-4-benzyloxymethyl-1-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)bicyclo<3.1.0>hexane

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 77.5 percent / LiClO4 / acetonitrile / 96 h / 70 °C
2: 98 percent / 1,1'-thiocarbonyldiimidazole, DMAP / dimethylformamide / 1.) r.t., 3 h, 2.) 70 deg C, 30 min
3: 96.5 percent / CHCl3; diethyl ether / 72 h / 0 °C
4: benzophenone / benzene; acetonitrile / 2 h / Irradiation
5: 25percent aq. NaOH / methanol / 24 h / Heating
6: Et3N, DPPA / toluene / 1.) r.t., 2 h, 2.) 80 deg C, 2 h
7: toluene / 1.) 80 deg C, 2 h, 2.) r.t., overnight
8: 99 percent / Bu4NF / acetonitrile; tetrahydrofuran / 4 h / 70 °C
9: 85.5 percent / CH2Cl2 / 24 h / Ambient temperature
10: 2 M HCl / ethanol / 30 h / Heating
View Scheme

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