As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis
Cas:110877-64-0
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:110877-64-0
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquirychengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
Cas:110877-64-0
Min.Order:10 Kilogram
FOB Price: $95.0 / 100.0
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:110877-64-0
Min.Order:1
Negotiable
Type:Other
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:110877-64-0
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:110877-64-0
Min.Order:1 Kilogram
FOB Price: $10.0 / 16.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:110877-64-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam
Cas:110877-64-0
Min.Order:1 Kilogram
FOB Price: $7.0 / 10.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:110877-64-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct Name: 2-Chloro-4,5-difluorobenzoic acid Synonyms: RARECHEM AL BO 1000;TIMTEC-BB SBB003616;2-CHLORO-4,5-DIFLUOROBENZOIC ACID;2-CHLORO-4 5-DIFLUOROBENZENE ACID 98%;2-Chloro-4,5-difluorobenzoic acid, 99+%;2-Chloro-4,5-difluorobenzoic acid
Cas:110877-64-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry2-Chloro-4,5-difluorobenzoic acid CAS:110877-64-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit
Cas:110877-64-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:110877-64-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryMinimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,
Cas:110877-64-0
Min.Order:10 Gram
Negotiable
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:110877-64-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:110877-64-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryOur advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s
Cas:110877-64-0
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
Cas:110877-64-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:110877-64-0
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:110877-64-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryWhy Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:110877-64-0
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:110877-64-0
Min.Order:1 Milligram
Negotiable
Type:Trading Company
inquiryOur company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
Cas:110877-64-0
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:110877-64-0
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:110877-64-0
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:110877-64-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:110877-64-0
Min.Order:1 Metric Ton
FOB Price: $7.0 / 8.0
Type:Trading Company
inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use
Cas:110877-64-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Cas:110877-64-0
Min.Order:1 Kilogram
Negotiable
Type:Other
inquiry2'-chloro-4',5'-difluoroacetophenone
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With sodium hypochlorite Oxidation; | 90% |
With hydrogenchloride; sodium hypochlorite In dichloromethane | 85.1% |
With hydrogenchloride; sodium hypochlorite In dichloromethane | 85.1% |
With sodium hypochlorite for 6h; Heating; | 80% |
With hydrogenchloride; sodium hydroxide; sodium hypobromide; bromine; sodium hydrogensulfite In 1,4-dioxane; dichloromethane; water |
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With KF; benzenesulfonyl chloride In sulfolane; thionyl chloride | 75% |
2-chloro-4,5-difluoro-α-chloroacetophenone
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With sodium hypochlorite Oxidation; |
4-chloro-1,2-difluorobenzene
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 80 percent / AlCl3 2: 90 percent / 5 percent NaOCl View Scheme | |
Multi-step reaction with 2 steps 1: 95 percent / AlCl3 2: 5 percent NaOCl View Scheme | |
Multi-step reaction with 2 steps 1: 75 percent / AlCl3 / 9 h / 60 °C 2: 80 percent / NaOCl / 6 h / Heating View Scheme |
2-fluoro-5-chloronitrobenzene
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: H2 / 5 percent Pt/C / 1,2-dimethoxy-ethane / 24 h / 2585.74 Torr 2: BF3*Et2O; t-BuONO / 1,2-dimethoxy-ethane / 1 h / -5 °C 3: 49 percent / 0.5 h / 170 °C 4: 80 percent / AlCl3 5: 90 percent / 5 percent NaOCl View Scheme | |
Multi-step reaction with 5 steps 1: H2 / 5 percent Pt/C / 1,2-dimethoxy-ethane / 24 h / 2585.74 Torr 2: BF3*Et2O; t-BuONO / 1,2-dimethoxy-ethane / 1 h / -5 °C 3: 49 percent / 0.5 h / 170 °C 4: 95 percent / AlCl3 5: 5 percent NaOCl View Scheme |
5-chloro-2-fluoroaniline
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: BF3*Et2O; t-BuONO / 1,2-dimethoxy-ethane / 1 h / -5 °C 2: 49 percent / 0.5 h / 170 °C 3: 80 percent / AlCl3 4: 90 percent / 5 percent NaOCl View Scheme | |
Multi-step reaction with 4 steps 1: BF3*Et2O; t-BuONO / 1,2-dimethoxy-ethane / 1 h / -5 °C 2: 49 percent / 0.5 h / 170 °C 3: 95 percent / AlCl3 4: 5 percent NaOCl View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 52 percent / KF; 18-crown-6 / tetrahydrothiophene 1,1-dioxide / 32 h / 180 °C 2: H2 / 5 percent Pt/C / 1,2-dimethoxy-ethane / 24 h / 2585.74 Torr 3: BF3*Et2O; t-BuONO / 1,2-dimethoxy-ethane / 1 h / -5 °C 4: 49 percent / 0.5 h / 170 °C 5: 80 percent / AlCl3 6: 90 percent / 5 percent NaOCl View Scheme | |
Multi-step reaction with 6 steps 1: 52 percent / KF; 18-crown-6 / tetrahydrothiophene 1,1-dioxide / 32 h / 180 °C 2: H2 / 5 percent Pt/C / 1,2-dimethoxy-ethane / 24 h / 2585.74 Torr 3: BF3*Et2O; t-BuONO / 1,2-dimethoxy-ethane / 1 h / -5 °C 4: 49 percent / 0.5 h / 170 °C 5: 95 percent / AlCl3 6: 5 percent NaOCl View Scheme |
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 49 percent / 0.5 h / 170 °C 2: 80 percent / AlCl3 3: 90 percent / 5 percent NaOCl View Scheme | |
Multi-step reaction with 3 steps 1: 49 percent / 0.5 h / 170 °C 2: 95 percent / AlCl3 3: 5 percent NaOCl View Scheme |
ortho-difluorobenzene
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 90 percent / FeCl3, Cl2 / 3 h / 50 °C 2: 75 percent / AlCl3 / 9 h / 60 °C 3: 80 percent / NaOCl / 6 h / Heating View Scheme |
2-chloro-4,5-difluorobenzotrichloride
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With sulfuric acid | |
With sulfuric acid |
Conditions | Yield |
---|---|
With sulfuric acid In water; acetic acid |
water
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride; sodium hydroxide; bromine In sodium hypobromide |
2-chloro-4,5-difluoro-α-chloroacetophenone
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride In sodium hypobromide |
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride In sodium hypochlorite |
tert.-butylnitrite
2-amino-4,5-difluorobenzoic acid
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride In water; acetonitrile |
2-amino-4,5-difluorobenzoic acid
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With sodium nitrate; copper(l) chloride In hydrogenchloride; water |
2-chloro-4,5-difluorobenzoic acid
2-chloro-4,5-difluorobenzoyl chloride
Conditions | Yield |
---|---|
With pyridine; thionyl chloride In toluene | 92.1% |
With N,N-dimethyl-formamide In dichloromethane for 3h; Ambient temperature; | |
With thionyl chloride; N,N-dimethyl-formamide for 2h; Heating; |
methanol
2-chloro-4,5-difluorobenzoic acid
2-Chloro-4,5-difluorobenzoic acid methyl ester
Conditions | Yield |
---|---|
With sulfuric acid at 60℃; for 48h; | 86.6% |
With acetyl chloride at 0℃; | 84% |
With acetyl chloride at 20℃; Cooling with ice; | |
With acetyl chloride for 65h; Reflux; |
2-chloro-4,5-difluorobenzoic acid
acetyl chloride
2-Chloro-4,5-difluorobenzoic acid methyl ester
Conditions | Yield |
---|---|
In methanol | 84% |
copper (I) acetate
2-chloro-4,5-difluorobenzoic acid
3-methyl-1-(2-pyridinyl)-1H-pyrazol-5-ylamine
4,5-difluoro-2-[[3-methyl-1-(2-pyridinyl)-1H-pyrazol-5-yl]amino]benzoic acid
Conditions | Yield |
---|---|
With potassium carbonate; acetic acid In N,N-dimethyl-formamide | 81% |
With potassium carbonate; acetic acid In N,N-dimethyl-formamide | 81% |
2-chloro-4,5-difluorobenzoic acid
metronidazole
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl 2-chloro-4,5-difluorobenzoate
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; | 80% |
3-methyl-1-(6-methylpyridin-2-yl)-1H-pyrazol-5-amine
copper (I) acetate
2-chloro-4,5-difluorobenzoic acid
A
4-chloro-6,7-difluoro-3-methyl-1-(6-methyl-2-pyridinyl)-1H-pyrazolo[3,4-b]quinoline
B
4,5-difluoro-2-[[3-methyl-1-(6-methyl-2-pyridinyl)-1H-pyrazol-5-yl]amino]benzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride; potassium carbonate In N,N-dimethyl-formamide | A 39% B 79% |
2-chloro-4,5-difluorobenzoic acid
4-amino-5-(3-pyridyl)-4H-1,2,4-triazole-3-thiol
Conditions | Yield |
---|---|
With trichlorophosphate for 6h; Reflux; | 79% |
2-chloro-4,5-difluorobenzoic acid
phenylmethanethiol
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 70℃; for 6h; | 79% |
2-chloro-4,5-difluorobenzoic acid
2-chloro-4,5-difluorobenzamide
Conditions | Yield |
---|---|
Stage #1: 2-chloro-4,5-difluorobenzoic acid With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Stage #2: With ammonia In water; N,N-dimethyl-formamide at 0 - 20℃; for 0.5h; | 76% |
Stage #1: 2-chloro-4,5-difluorobenzoic acid With thionyl chloride In toluene at 60℃; for 1.5h; Heating / reflux; Stage #2: With pyridine In toluene at 60℃; for 1.5h; Stage #3: With ammonia In toluene at 20 - 35℃; |
2-chloro-4,5-difluorobenzoic acid
benzylamine
N-benzyl-2-chloro-4,5-difluorobenzamide
Conditions | Yield |
---|---|
Stage #1: 2-chloro-4,5-difluorobenzoic acid With triethylamine; isobutyl chloroformate In dichloromethane for 0.25h; Inert atmosphere; Schlenk technique; Stage #2: benzylamine In dichloromethane at 0℃; | 76% |
2-chloro-4,5-difluorobenzoic acid
4-amino-3-(2-furyl)-5-mercapto[4H]-1,2,4-triazole
Conditions | Yield |
---|---|
With trichlorophosphate Reflux; | 75% |
4-amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol
2-chloro-4,5-difluorobenzoic acid
6-(2-chloro-4,5-difluorophenyl)-3-(pyridin-4-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Conditions | Yield |
---|---|
With trichlorophosphate Reflux; | 74% |
2-Amino-4,6-dimethylpyridine
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With O-phenyl phosphorodichloridate; triethylamine In 1,2-dichloro-ethane at 20℃; for 24h; | 72% |
3-ethyl-1-(2-pyridinyl)-1H-pyrazol-5-ylamine
copper (I) acetate
2-chloro-4,5-difluorobenzoic acid
A
4-chloro-3-ethyl-6,7-difluoro-1-(2-pyridinyl)-1H-pyrazolo[3,4-b]quinoline
B
4,5-difluoro-2-[[3-ethyl-1-(2-pyridinyl)-1H-pyrazol-5-yl]amino]benzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride; potassium carbonate In N,N-dimethyl-formamide | A 50% B 66% |
ethanamine hydrochloride
2-chloro-4,5-difluorobenzoic acid
Conditions | Yield |
---|---|
With potassium phosphate; copper(l) iodide In N,N-dimethyl-formamide at 140℃; for 1.5h; Microwave irradiation; | 65% |
copper (I) acetate
2-chloro-4,5-difluorobenzoic acid
A
4-chloro-6,7-difluoro-3-methyl-1-(3-pyridinyl)-1H-pyrazolo[3,4-b]quinoline
Conditions | Yield |
---|---|
With hydrogenchloride; potassium carbonate In N,N-dimethyl-formamide | A 8% B 63% |
2-chloro-4,5-difluorobenzoic acid
1,1,1,3,3,3-hexamethyl-disilazane
Conditions | Yield |
---|---|
With iodine In neat (no solvent) at 20℃; for 96h; Green chemistry; | 62% |
Conditions | Yield |
---|---|
With tetrabutyl-ammonium chloride; palladium diacetate; potassium carbonate; Tri(p-tolyl)phosphine In N,N-dimethyl-formamide at 140℃; for 12h; Schlenk technique; Inert atmosphere; | 58% |
2-chloro-4,5-difluorobenzoic acid
1,2-cyclooctene
Conditions | Yield |
---|---|
With N-Bromosuccinimide; 5,6-difluoro-2-(1-phenylethyl)benzo[d][1,2]selenazol-3(2H)-one In dichloromethane at 20℃; for 8h; | 56% |
copper (I) acetate
2-chloro-4,5-difluorobenzoic acid
1-(2-pyridinyl)-1H-pyrazol-5-ylamine
4,5-difluoro-2-[[1-(2-pyridinyl)-1H-pyrazol-5-yl]amino]benzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride; potassium carbonate In N,N-dimethyl-formamide | 55% |
Conditions | Yield |
---|---|
Stage #1: dysprosium(III) nitrate hexahydrate; N-Methyldiethanolamine; chromium(III) chloride hexahydrate; 2-chloro-4,5-difluorobenzoic acid With triethylamine In acetonitrile for 2h; Stage #2: methanol In diethyl ether | 49% |
Conditions | Yield |
---|---|
Stage #1: terbium(III) nitrate hexahydrate; N-Methyldiethanolamine; chromium(III) chloride hexahydrate; 2-chloro-4,5-difluorobenzoic acid With triethylamine In acetonitrile for 2h; Stage #2: methanol In diethyl ether | 42% |
Conditions | Yield |
---|---|
Stage #1: holmium(III) nitrate hexahydrate; N-Methyldiethanolamine; chromium(III) chloride hexahydrate; 2-chloro-4,5-difluorobenzoic acid With triethylamine In acetonitrile for 2h; Stage #2: methanol In diethyl ether | 39% |
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