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Hangzhou Dingyan Chem Co., Ltd

Analysis tests Standard Results Appearance Light yellow transparency liquid Conforms Purity

Top purity tert-butyl cyanoacetate with high quality and best price cas:1116-98-9

Cas:1116-98-9

Min.Order:1 Gram

FOB Price: $2.0 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cyanoacetic acid tert-butyl ester

Cas:1116-98-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

tert-Butyl cyanoacetate CAS NO.1116-98-9

Cas:1116-98-9

Min.Order:1 Gram

FOB Price: $1.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tert-Butyl cyanoacetate 1116-98-9

Cas:1116-98-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 1116-98-9 with competitive price

Cas:1116-98-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name tert-Butyl cyanoacetate Synonyms T-BUTYL CYANOACETATE CAS: 1116-98-9 Product Categories: Agrochemical Intermediates;Intermediates & Fine Chemical

Tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Acetic acid, 2-cyano-,1,1-dimethylethyl ester 1116-98-9

Cas:1116-98-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

tert-Butyl cyanoacetate 99%

Cas:1116-98-9

Min.Order:1 Kilogram

FOB Price: $50.0 / 54.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

tert-Butyl cyanoacetate CAS:1116-98-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

tert-Butyl cyanoacetate CAS:1116-98-9

Cas:1116-98-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Acetic acid, 2-cyano-,1,1-dimethylethyl ester

Cas:1116-98-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

tert-Butyl cyanoacetate CAS NO.1116-98-9

Cas:1116-98-9

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

tert-Butyl cyanoacetate CAS:1116-98-9 Specification Appearance & Physical State: colorless liquid Density: 0.988 Melting Point: 107-108ºC

Factory supply tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Acetic acid, 2-cyano-,1,1-dimethylethyl ester

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Wholesale high purity tert-Butyl cyanoacetate 1116-98-9 in bulk price

Cas:1116-98-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply tert-butyl cyanoacetate

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Other

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Wholesale high purity tert-Butyl cyanoacetate 1116-98-9 in bulk price

Cas:1116-98-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Wholesale high purity tert-Butyl cyanoacetate 1116-98-9 in bulk price

Cas:1116-98-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Wholesale high purity tert-Butyl cyanoacetate 1116-98-9 in bulk price

Cas:1116-98-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Wholesale high purity tert-Butyl cyanoacetate 1116-98-9 in bulk price

Cas:1116-98-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

tert-Butyl cyanoacetate cas no. 1116-98-9 98%

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

tert-Butyl cyanoacetate

Cas:1116-98-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

tert-butyl cyanoacetateAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

tert-butyl cyanoacetate

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

tert-butyl cyanoacetate

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Cyanoacetic acid tert-Butyl ester

Cas:1116-98-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

cyanoacetic acid
372-09-8

cyanoacetic acid

isobutene
115-11-7

isobutene

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In tetrahydrofuran at 10℃; under 12001.2 - 14251.4 Torr; for 0.133333h; Temperature; Solvent;98%
With boron trifluoride diethyl etherate In dichloromethane at 10℃; for 7h; Reagent/catalyst; Temperature; Solvent; Large scale;90%
With sulfuric acid; tert-butyl alcohol at -20℃;
cyanoacetic acid
372-09-8

cyanoacetic acid

tert-butyl alcohol
75-65-0

tert-butyl alcohol

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere;86%
With dicyclohexyl-carbodiimide In acetonitrile at 25℃; for 5h;84%
With dicyclohexyl-carbodiimide In dichloromethane at 25℃; for 0.25h;75%
tert-Butyl chloroacetate
107-59-5

tert-Butyl chloroacetate

potassium cyanide
151-50-8

potassium cyanide

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With sodium iodide; tert-butyl alcohol
tert-Butyl chloroacetate
107-59-5

tert-Butyl chloroacetate

potassium cyanide
151-50-8

potassium cyanide

A

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

B

cyano-succinic acid di-tert-butyl ester
106271-05-0

cyano-succinic acid di-tert-butyl ester

Conditions
ConditionsYield
With water; tert-butyl alcohol
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

potassium cyanide
151-50-8

potassium cyanide

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With methanol
cyanoacetic acid chloride
16130-58-8

cyanoacetic acid chloride

tert-butyl alcohol
75-65-0

tert-butyl alcohol

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With diethyl ether; N,N-dimethyl-aniline
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

tetraethylammoniumcyanide
13435-20-6

tetraethylammoniumcyanide

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
In dichloromethane
C23H25I2NO2

C23H25I2NO2

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C29H35I2NO4

C29H35I2NO4

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 50℃;100%
bromobenzene
108-86-1

bromobenzene

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

9-methyl-9H-fluorene-9-carbonyl chloride
82102-37-2

9-methyl-9H-fluorene-9-carbonyl chloride

Benzoylacetonitrile
614-16-4

Benzoylacetonitrile

Conditions
ConditionsYield
Stage #1: bromobenzene; cyanoacetic acid tert-butyl ester; 9-methyl-9H-fluorene-9-carbonyl chloride With dichloro(1,5-cyclooctadiene)palladium(II); N-Methyldicyclohexylamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; magnesium chloride; tri tert-butylphosphoniumtetrafluoroborate In 1,4-dioxane at 100℃; for 18h; Glovebox; Inert atmosphere;
Stage #2: With formic acid In 1,4-dioxane Reagent/catalyst; Inert atmosphere;
100%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

2,4-dibromo-1,3-thiazole
4175-77-3

2,4-dibromo-1,3-thiazole

tert-butyl 2-(4-bromothiazol-2-yl)-2-cyanoacetate

tert-butyl 2-(4-bromothiazol-2-yl)-2-cyanoacetate

Conditions
ConditionsYield
With potassium carbonate In 1-methyl-pyrrolidin-2-one for 16h;100%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

cyclohexanone
108-94-1

cyclohexanone

2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid tert-butyl ester
92932-02-0

2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With morpholine; sulfur In ethanol at 50℃;99%
With sulfur; diethylamine In ethanol Gewald cyclization; Reflux;95%
With morpholine; sulfur In ethanol at 45℃; for 5h;89%
morpholine
110-91-8

morpholine

2-methyltetrahydro-4H-pyran-4-one
1193-20-0

2-methyltetrahydro-4H-pyran-4-one

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

tert-butyl 2-amino-5-methyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate
1373497-01-8

tert-butyl 2-amino-5-methyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate

Conditions
ConditionsYield
With hydrogen sulfide In ethanol; ethyl acetate99%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

(6-chloropyridazin-3-yl)-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]methanone

(6-chloropyridazin-3-yl)-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]methanone

tert-butyl 2-cyano-2-[6-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carbonyl]pyridazin-3-yl]acetate

tert-butyl 2-cyano-2-[6-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carbonyl]pyridazin-3-yl]acetate

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester With sodium hydride In 1,4-dioxane at 20℃; for 1h;
Stage #2: (6-chloropyridazin-3-yl)-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]methanone In 1,4-dioxane at 100℃; for 16h;
99%
cyanoacetic acid
372-09-8

cyanoacetic acid

isobutene
115-11-7

isobutene

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In tetrahydrofuran at 10℃; under 12001.2 - 14251.4 Torr; for 0.133333h; Temperature; Solvent;98%
With boron trifluoride diethyl etherate In dichloromethane at 10℃; for 7h; Reagent/catalyst; Temperature; Solvent; Large scale;90%
With sulfuric acid; tert-butyl alcohol at -20℃;
cyanoacetic acid
372-09-8

cyanoacetic acid

tert-butyl alcohol
75-65-0

tert-butyl alcohol

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere;86%
With dicyclohexyl-carbodiimide In acetonitrile at 25℃; for 5h;84%
With dicyclohexyl-carbodiimide In dichloromethane at 25℃; for 0.25h;75%
tert-Butyl chloroacetate
107-59-5

tert-Butyl chloroacetate

potassium cyanide
151-50-8

potassium cyanide

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With sodium iodide; tert-butyl alcohol
tert-Butyl chloroacetate
107-59-5

tert-Butyl chloroacetate

potassium cyanide
151-50-8

potassium cyanide

A

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

B

cyano-succinic acid di-tert-butyl ester
106271-05-0

cyano-succinic acid di-tert-butyl ester

Conditions
ConditionsYield
With water; tert-butyl alcohol
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

potassium cyanide
151-50-8

potassium cyanide

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With methanol
cyanoacetic acid chloride
16130-58-8

cyanoacetic acid chloride

tert-butyl alcohol
75-65-0

tert-butyl alcohol

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
With diethyl ether; N,N-dimethyl-aniline
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

tetraethylammoniumcyanide
13435-20-6

tetraethylammoniumcyanide

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

Conditions
ConditionsYield
In dichloromethane
C23H25I2NO2

C23H25I2NO2

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C29H35I2NO4

C29H35I2NO4

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 50℃;100%
bromobenzene
108-86-1

bromobenzene

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

9-methyl-9H-fluorene-9-carbonyl chloride
82102-37-2

9-methyl-9H-fluorene-9-carbonyl chloride

Benzoylacetonitrile
614-16-4

Benzoylacetonitrile

Conditions
ConditionsYield
Stage #1: bromobenzene; cyanoacetic acid tert-butyl ester; 9-methyl-9H-fluorene-9-carbonyl chloride With dichloro(1,5-cyclooctadiene)palladium(II); N-Methyldicyclohexylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; magnesium chloride; tri tert-butylphosphoniumtetrafluoroborate In 1,4-dioxane at 100℃; for 18h; Glovebox; Inert atmosphere;
Stage #2: With formic acid In 1,4-dioxane Reagent/catalyst; Inert atmosphere;
100%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

2,4-dibromo-1,3-thiazole
4175-77-3

2,4-dibromo-1,3-thiazole

tert-butyl 2-(4-bromothiazol-2-yl)-2-cyanoacetate

tert-butyl 2-(4-bromothiazol-2-yl)-2-cyanoacetate

Conditions
ConditionsYield
With potassium carbonate In 1-methyl-pyrrolidin-2-one for 16h;100%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

cyclohexanone
108-94-1

cyclohexanone

2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid tert-butyl ester
92932-02-0

2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With morpholine; sulfur In ethanol at 50℃;99%
With sulfur; diethylamine In ethanol Gewald cyclization; Reflux;95%
With morpholine; sulfur In ethanol at 45℃; for 5h;89%
morpholine
110-91-8

morpholine

2-methyltetrahydro-4H-pyran-4-one
1193-20-0

2-methyltetrahydro-4H-pyran-4-one

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

tert-butyl 2-amino-5-methyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate
1373497-01-8

tert-butyl 2-amino-5-methyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate

Conditions
ConditionsYield
With hydrogen sulfide In ethanol; ethyl acetate99%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

(6-chloropyridazin-3-yl)-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]methanone

(6-chloropyridazin-3-yl)-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]methanone

tert-butyl 2-cyano-2-[6-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carbonyl]pyridazin-3-yl]acetate

tert-butyl 2-cyano-2-[6-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carbonyl]pyridazin-3-yl]acetate

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester With sodium hydride In 1,4-dioxane at 20℃; for 1h;
Stage #2: (6-chloropyridazin-3-yl)-[2-(indan-2-ylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]methanone In 1,4-dioxane at 100℃; for 16h;
99%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

3 -bromo-6-chloro-2-methoxypyridine

3 -bromo-6-chloro-2-methoxypyridine

methyl iodide
74-88-4

methyl iodide

2-(6-chloro-2-methoxypyridin-3-yl)propanenitrile

2-(6-chloro-2-methoxypyridin-3-yl)propanenitrile

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester; 3 -bromo-6-chloro-2-methoxypyridine With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium t-butanolate In 1,4-dioxane at 75℃; for 3.91667h; Inert atmosphere;
Stage #2: methyl iodide In 1,4-dioxane at 20℃;
99%
Stage #1: cyanoacetic acid tert-butyl ester; 3 -bromo-6-chloro-2-methoxypyridine With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium t-butanolate In 1,4-dioxane at 75℃; for 3.91667h; Inert atmosphere;
Stage #2: methyl iodide In 1,4-dioxane at 18 - 25℃;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C15H18N2O2

C15H18N2O2

C22H28N2O2

C22H28N2O2

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester; C15H18N2O2 With C39H38N3O2P; potassium carbonate; silver(l) oxide at 20℃; for 24h;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene for 6h; enantioselective reaction;
99%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C13H12N2O4

C13H12N2O4

C20H22N2O4

C20H22N2O4

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester; C13H12N2O4 With C39H38N3O2P; potassium carbonate; silver(l) oxide In toluene at 0℃; for 24h;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene for 6h; enantioselective reaction;
99%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C21H16N2O5S

C21H16N2O5S

C28H26N2O5S

C28H26N2O5S

Conditions
ConditionsYield
With C39H38N3O2P; potassium carbonate; silver(l) oxide at 20℃; enantioselective reaction;99%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

4-chlorobenzoic anhydride
790-41-0

4-chlorobenzoic anhydride

tert-butyl 2-(4-chlorophenyl)-2-cyanoacetate
724767-52-6

tert-butyl 2-(4-chlorophenyl)-2-cyanoacetate

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -45℃; for 0.75h; Inert atmosphere;
Stage #2: 4-chlorobenzoic anhydride In tetrahydrofuran; hexane at -45℃; for 1h; Inert atmosphere;
98%
Stage #1: cyanoacetic acid tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran; hexane at -45℃; for 0.75h;
Stage #2: 4-chlorobenzoic anhydride In tetrahydrofuran; hexane at -45 - 20℃; Further stages.;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

5-Bromo-2-chloropyrimidine
32779-36-5

5-Bromo-2-chloropyrimidine

tert-butyl 2-(5-bromopyrimidin-2-yl)-2-cyanoacetic acid
1305329-97-8

tert-butyl 2-(5-bromopyrimidin-2-yl)-2-cyanoacetic acid

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: 5-Bromo-2-chloropyrimidine In tetrahydrofuran at 20℃; for 18h;
98%
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 80℃; for 3h;35.72%
2-chloro-5-nitro-3-(trifluoromethyl)pyridine
99368-67-9

2-chloro-5-nitro-3-(trifluoromethyl)pyridine

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

tert-butyl 2-cyano-2-(5-nitro-3-(trifluoromethyl)pyridin-2-yl)acetate

tert-butyl 2-cyano-2-(5-nitro-3-(trifluoromethyl)pyridin-2-yl)acetate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 50℃; for 10h;98%
With potassium carbonate In tetrahydrofuran at 50℃; for 10h; Temperature;98%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

2,4,5,6-tetrafluoropyrimidine
767-79-3

2,4,5,6-tetrafluoropyrimidine

potassium-2-(tert-butoxy)-1-cyano-2-oxo-1-(2,5,6-trifluoropyrimidin-4-yl)ethan-1-ide

potassium-2-(tert-butoxy)-1-cyano-2-oxo-1-(2,5,6-trifluoropyrimidin-4-yl)ethan-1-ide

Conditions
ConditionsYield
Stage #1: 2,4,5,6-tetrafluoropyrimidine With potassium carbonate In acetonitrile
Stage #2: cyanoacetic acid tert-butyl ester In acetonitrile at 20℃; for 72h;
98%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C20H17NO5S

C20H17NO5S

C27H27NO5S

C27H27NO5S

Conditions
ConditionsYield
With C39H38N3O2P; potassium carbonate; silver(l) oxide at 20℃; Reagent/catalyst; enantioselective reaction;98%
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

tert-butyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
872530-68-2

tert-butyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate

Conditions
ConditionsYield
With morpholine; sulfur at 20℃; for 48h; Gewald Aminoheterocycles Synthesis;97%
With morpholine; sulfur In ethanol at 45℃; for 5h;86%
With morpholine; sulfur In ethanol at 50℃; for 2h;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

1-ethoxycarbonylmethyl-3-(1-pyrrolidinylmethylene)-3H-indolium bromide
75629-56-0

1-ethoxycarbonylmethyl-3-(1-pyrrolidinylmethylene)-3H-indolium bromide

2-cyano-3-(1-ethoxycarbonylmethyl-1H-indol-3-yl)-acrylic acid
866601-48-1

2-cyano-3-(1-ethoxycarbonylmethyl-1H-indol-3-yl)-acrylic acid

Conditions
ConditionsYield
With sodium ethanolate In ethanol; chloroform at 20℃;97%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

cycloheptanone
502-42-1

cycloheptanone

tert-butyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate
885115-88-8

tert-butyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate

Conditions
ConditionsYield
With morpholine; sulfur In ethanol at 45℃;97%
With morpholine; sulfur In ethanol for 16h; Gewald Aminoheterocycles Synthesis; Reflux;64%
With morpholine; sulfur In ethanol at 45℃; for 24h; Gewald Aminoheterocycles Synthesis;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

benzoic acid anhydride
93-97-0

benzoic acid anhydride

2-t-butoxycarbonyl-2-phenylacetonitrile
115549-32-1

2-t-butoxycarbonyl-2-phenylacetonitrile

Conditions
ConditionsYield
Stage #1: cyanoacetic acid tert-butyl ester With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -45℃; for 0.75h; Inert atmosphere;
Stage #2: benzoic acid anhydride In tetrahydrofuran; hexane at -45℃; for 1h; Inert atmosphere;
97%
Stage #1: cyanoacetic acid tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran; hexane at -45℃; for 0.75h;
Stage #2: benzoic acid anhydride In tetrahydrofuran; hexane at -45 - 20℃; Further stages.;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

tert-butyl α-cyano-α-diazoacetate
1236004-44-6

tert-butyl α-cyano-α-diazoacetate

Conditions
ConditionsYield
With perfluorobutanesulfonyl azide; triethylamine In dichloromethane at 20℃; Inert atmosphere;97%
With sodium azide; 3-Carboxybenzenesulfonyl chloride; potassium carbonate In water at 20℃; for 1h;71%
With pyridine; triflic azide In hexane; acetonitrile for 24h; Inert atmosphere;69%
With pyridine; triflic azide In hexane; acetonitrile at 20℃; for 24h; Inert atmosphere;
Stage #1: cyanoacetic acid tert-butyl ester With potassium carbonate; Methanesulfonyl azide In water at 20℃;
Stage #2: With water; potassium carbonate at 20℃; for 3h;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

4,6-dimethoxypyrimidin-2-yl methyl sulfone
113583-35-0

4,6-dimethoxypyrimidin-2-yl methyl sulfone

tert-butyl 2-cyano-2-(4,6-dimethoxypyrimidin-2-yl)acetate
1225226-84-5

tert-butyl 2-cyano-2-(4,6-dimethoxypyrimidin-2-yl)acetate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60 - 70℃; for 6h; Inert atmosphere;97%
With potassium carbonate In acetonitrile for 24h; Reflux;87.3%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

5-(2-bromophenyl)-4-phenyl-1H-1,2,3-triazole

5-(2-bromophenyl)-4-phenyl-1H-1,2,3-triazole

tert-butyl 5-amino-1-phenyl[1,2,3]triazolo[5,1-a]isoquinoline-6-carboxylate

tert-butyl 5-amino-1-phenyl[1,2,3]triazolo[5,1-a]isoquinoline-6-carboxylate

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In dimethyl sulfoxide at 80℃; Inert atmosphere; Schlenk technique; Sealed tube; chemoselective reaction;97%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

5-(2-bromophenyl)-4-(4-nitrophenyl)-1H-1,2,3-triazole

5-(2-bromophenyl)-4-(4-nitrophenyl)-1H-1,2,3-triazole

tert-butyl 5-amino-1-(4-nitrophenyl)[1,2,3]triazolo[5,1-a]isoquinoline-6-carboxylate

tert-butyl 5-amino-1-(4-nitrophenyl)[1,2,3]triazolo[5,1-a]isoquinoline-6-carboxylate

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In dimethyl sulfoxide at 80℃; Inert atmosphere; Schlenk technique; Sealed tube; chemoselective reaction;97%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C56H57NOS3

C56H57NOS3

C63H66N2O2S3

C63H66N2O2S3

Conditions
ConditionsYield
With piperidine In tetrahydrofuran96%
bromobenzene
108-86-1

bromobenzene

cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

9-methylfluorene-9-([(13)C]-carbonyl) chloride
1072315-89-9

9-methylfluorene-9-([(13)C]-carbonyl) chloride

[3-13C]-3-oxo-3-phenylpropanenitrile

[3-13C]-3-oxo-3-phenylpropanenitrile

Conditions
ConditionsYield
Stage #1: bromobenzene; cyanoacetic acid tert-butyl ester; 9-methylfluorene-9-([(13)C]-carbonyl) chloride With dichloro(1,5-cyclooctadiene)palladium(II); N-Methyldicyclohexylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; magnesium chloride; tri tert-butylphosphoniumtetrafluoroborate In 1,4-dioxane at 100℃; for 18h; Glovebox; Inert atmosphere;
Stage #2: With formic acid In 1,4-dioxane Inert atmosphere;
96%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

5-ethoxy-1-methyl-3,4-dihydro-2H-pyrrolium; tetrafluoroborate
41948-92-9

5-ethoxy-1-methyl-3,4-dihydro-2H-pyrrolium; tetrafluoroborate

Cyano-[1-methyl-pyrrolidin-(2E)-ylidene]-acetic acid tert-butyl ester
125138-99-0

Cyano-[1-methyl-pyrrolidin-(2E)-ylidene]-acetic acid tert-butyl ester

Conditions
ConditionsYield
With sodium methylate In tetrahydrofuran for 1h; Ambient temperature;95%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

C20H14NO(1+)*I3(1-)
86194-06-1

C20H14NO(1+)*I3(1-)

Cyano-[1-oxo-2,3-diphenyl-1H-indolizin-(7E)-ylidene]-acetic acid tert-butyl ester
121030-45-3

Cyano-[1-oxo-2,3-diphenyl-1H-indolizin-(7E)-ylidene]-acetic acid tert-butyl ester

Conditions
ConditionsYield
With pyridine for 1h; Ambient temperature;95%
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

(E)-tert-butyl 2-cyano-3-(4-hydroxyphenyl)acrylate

(E)-tert-butyl 2-cyano-3-(4-hydroxyphenyl)acrylate

Conditions
ConditionsYield
With C8H18NO3(1+)*C2H4NO2(1-) In water at 20℃; Knoevenagel Condensation;95%
With piperidine In dichloromethane at 20℃; for 20h; Knoevenagel Condensation; Inert atmosphere;71%
With piperidine In ethanol Heating;
With piperidine In dichloromethane at 20℃; Inert atmosphere;
cyanoacetic acid tert-butyl ester
1116-98-9

cyanoacetic acid tert-butyl ester

benzaldehyde
100-52-7

benzaldehyde

α-Cyanzimtsaeure-tert-butylester
1145-55-7

α-Cyanzimtsaeure-tert-butylester

Conditions
ConditionsYield
quaternary ammonium-ordered porous silicate composite In benzene at 80℃; for 6h; Knoevenagel condensation;95%
With piperidine In ethanol at 70℃; for 19h;76%
With C21H13N3O6(2-)*Zn(2+)*2H2O In tetrahydrofuran at 50℃; for 1.5h; Knoevenagel Condensation;45%

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