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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

2,6,6-Trimethyl-2-cyclohexene-1,4-dione suppliers in China

Cas:1125-21-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Oxoisophorone supplier in China

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity Various Specifications 4-oxoisophorone CAS:1125-21-9

Cas:1125-21-9

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:white po

4-Ketoisophorone

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

High Quality Oxoisophorone

Cas:1125-21-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% 4-oxoisophorone 1125-21-9 Producer

Cas:1125-21-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2,6,6-Trimethyl-2-Cyclohexene-1,4-Dione

Cas:1125-21-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM -2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Technical Details 2,6,6-Trimethyl-2-cyclohexene-1,4-dione Chemical Properties Melting point 26-28 °C (lit.) Boiling point 222 °C (lit.) 92-94 °C/11 mmHg (lit.)

China Largest factory Manufacturer Supply 2,6,6-Trimethyl-2-cyclohexene-1,4-dione/4-Ketoisophorone CAS 1125-21-9

Cas:1125-21-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New CAS 1125-21-9 with high quality products

Cas:1125-21-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name 2 6 6-Trimethyl-2-cyclohexene-1 4-dione Synonyms 2,2,6-trimethyl-2-cyclohexene-1,4-dione (cetoisophorone);2,2,6-trimethylcyclohex-2-en-1,4-dione (4-oxo-isophorone);2,6,6-Trimethy-2-cyclo

2,6,6-Trimethyl-2-cyclohexene-1,4-dione CAS:1125-21-9

Cas:1125-21-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Pale Yellow to Yellow powder Storage:R T Package:25kg/Barrel Application:It can be used for the blending of amber, citrus, tea and tobacco flavors. Transportation:Express/Sea/Air Port:Any port in China

Cheap Price Ready Stock 2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Cyclohexene-1,4-dione,2,6,6-trimethyl- 1125-21-9

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Price, service, company and transport advantage: 1.place of origin china with super quality by reasonable price. 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's customers' right to

BEST PRICE/2,6,6-Trimethyl-2-cyclohexene-1,4-dione CAS NO.1125-21-9

Cas:1125-21-9

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

2,6,6-Trimethyl-2-cyclohexene-1,4-dione CAS:1125-21-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qu

2,6,6-Trimethyl-2-cyclohexene-1,4-dione CAS:1125-21-9

Cas:1125-21-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Cyclohexene-1,4-dione,2,6,6-trimethyl-

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 1125-21-9 2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Cyclohexene-1,4-dione,2,6,6-trimethyl-

Cas:1125-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Yuance Industry&Trade Co., Ltd.

Competitive price with fast delivery Excellent product quality with 98% purity Appearance:pale yellow to yellow liquid Storage:Store in cool dry place Package:drum packing Application:Flavor and fragrance Port:Shanghai, Nanjing

4-oxo-isophorone, Keto isophorone,4-Keto isophorone,

Cas:1125-21-9

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

JINING XINHE CHEMICAL CO., LTD

Advantage 1: The product passed the professional production process and quality inspection, the purity is 99% +. 2: Highly qualified engineers to provide technical documents and service. 3: We could provide sample for your test. 4: High qualit

Tea aroma ketone1125-21-92,6,6-trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

Donglian as a factory and supplier of aroma chemicals in China, We can provide different quantities of custom synthesis chemicals in food flavor scale more than fourteen years.in addition, our company has researched and developed four series

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-oxo-isophorone

Cas:1125-21-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Oxoisophorone

Cas:1125-21-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality moderate price & quick delivery Appearance:clear yellow to orange liquid or low melting solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your requ

4-oxoisophorone

Cas:1125-21-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

High quality Oxoisophorone supplier in China

Cas:1125-21-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2,6,6-Trimethyl-2-cyclohexene-1,4-dione CAS: 1125-21-9 MF: C9H12O2 MW: 152.19 EINECS: 214-406-2 Mol File: 1125-21-9.mol 2,6,6-Trimethyl-2-cyclohexene-1,4-dione Structure 2,6,6-Trimethyl-2-cyclohexene-1,4-dione Chemic

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Cas:1125-21-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With 2,5-Dimethyl-1,4-benzoquinone In toluene at 80℃; Reagent/catalyst; Solvent; Temperature;98.98%
With chromium(VI) oxide
With chromium(VI) oxide; sulfuric acid In acetone
With chromic acid
With sodium anthraquinone-2-sulfonate; oxygen In water at 30℃; Irradiation;
3,5,5-trimethylcyclohex-3-en-1-one
471-01-2

3,5,5-trimethylcyclohex-3-en-1-one

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With diisobutyl ketone; oxygen; 1,4-diaza-bicyclo[2.2.2]octane at 40℃; for 5h;93%
With (5,10,15,20-tetraphenylporphyrinato)manganese(III) chloride; oxygen; triethylamine In 1,2-dimethoxyethane; water for 9h; Ambient temperature;92%
62.8%
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With tert.-butylhydroperoxide; cobalt acetylacetonate In acetone at 28℃; for 15h; Solvent; Concentration; Temperature;79%
With tert.-butylhydroperoxide; bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; water In neat (no solvent) at 20℃; for 24h; Catalytic behavior; Mechanism; Reagent/catalyst; Solvent; Temperature; Sealed tube; regioselective reaction;78%
With tert.-butylhydroperoxide; bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]} In water at 20℃; for 24h; Catalytic behavior; Concentration; Temperature; Solvent; Time;78%
3,5,5-trimethylcyclohex-3-en-1-one
471-01-2

3,5,5-trimethylcyclohex-3-en-1-one

A

3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

C

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

Conditions
ConditionsYield
With Tri-n-octylamine; sodium tungstate (VI) dihydrate; phosphoric acid; dihydrogen peroxide In water at 70℃; for 2h; pH=1.5 - 2; Temperature; Reagent/catalyst;A 8%
B 24%
C 67%
With Tri-n-octylamine; sodium tungstate (VI) dihydrate; phosphoric acid; dihydrogen peroxide In water at 90℃; for 2h; pH=1.5 - 2; Catalytic behavior; Reagent/catalyst; Temperature;A 15%
B 46%
C 16%
With sodium tungstate (VI) dihydrate; phosphoric acid; dihydrogen peroxide In water at 80℃; for 2h; pH=1.5 - 2; Temperature;A 22%
B 5%
C 13%
With oxygen; triethylamine; iron tetrasulfophthalocyanine-TiO2 In dimethyl sulfoxide at 60℃; under 1500.12 Torr; for 24h;A 10 % Chromat.
B 57 % Chromat.
C 21 % Chromat.
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

2,3,6,7-tetrahydro-2,2,6,6-tetramethylanthracene-1,4,5,8-tetrone
96493-78-6

2,3,6,7-tetrahydro-2,2,6,6-tetramethylanthracene-1,4,5,8-tetrone

Conditions
ConditionsYield
With potassium dichromate; air; phosphomolybdic acid; copper(II) sulfate at 90 - 95℃; for 100h;A 56%
B n/a
With potassium dichromate; air; phosphpmolybdic acid; copper(II) sulfate at 90 - 95℃; for 100h; basic treatment during workup;
With potassium dichromate; phosphomolybdic acid; oxygen; copper(II) sulfate 1. 100 deg C, 100 hours; Multistep reaction;
(S)-4-Hydroxy-3,5,5-trimethyl-4-(toluene-4-sulfonylmethyl)-cyclohex-2-enone
518316-69-3

(S)-4-Hydroxy-3,5,5-trimethyl-4-(toluene-4-sulfonylmethyl)-cyclohex-2-enone

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃; for 0.3h;54%
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

isophorone oxide
10276-21-8

isophorone oxide

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

C

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

Conditions
ConditionsYield
With [2,2]bipyridinyl; silver(I) acetate; lithium perchlorate In water; acetonitrile electrochemical oxidation;
With N-hydroxyphthalimide; oxygen at 60℃; for 10h;
9-hydroxymegastigma-4,7-dien-3-one
896107-70-3

9-hydroxymegastigma-4,7-dien-3-one

A

3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

B

2,6,6-trimethyl-1,4-cyclohexanedione
20547-99-3

2,6,6-trimethyl-1,4-cyclohexanedione

C

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

D

4-(But-2-enylidene)-3,5,5-trimethylcyclohex-2-enone
13215-88-8

4-(But-2-enylidene)-3,5,5-trimethylcyclohex-2-enone

E

megastigmatrienone

megastigmatrienone

Conditions
ConditionsYield
In water Heating; pH=1;
alpha-ionone
127-41-3

alpha-ionone

A

dehydrovomifoliol
15764-81-5

dehydrovomifoliol

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

C

3,5,5-trimethyl-4-[(E)-3-oxo-1-butenyl]-2-cyclohexen-1-one
79734-43-3

3,5,5-trimethyl-4-[(E)-3-oxo-1-butenyl]-2-cyclohexen-1-one

Conditions
ConditionsYield
With t-butyl chromate In tert-butyl alcohol; benzene at 60℃;A 700 mg
B 105 mg
C 750 mg
6,9-dihydroxymegastigma-4,7-dien-3-one
23526-45-6, 24427-77-8, 50763-72-9, 50763-73-0

6,9-dihydroxymegastigma-4,7-dien-3-one

A

3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

B

2,3,5-trimethylphenol
697-82-5

2,3,5-trimethylphenol

C

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
Heating; pH=1;
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

2,6,6-trimethyl-1,4-cyclohexanedione
20547-99-3

2,6,6-trimethyl-1,4-cyclohexanedione

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

C

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

D

3-(hydroxymethyl)-5,5-dimethylcyclohex-2-en-1-one

3-(hydroxymethyl)-5,5-dimethylcyclohex-2-en-1-one

Conditions
ConditionsYield
In water at 28℃; for 96h; Aspergillus niger, culture broth;
In water at 28℃; for 96h; Aspergillus niger, culture broth; Yield given. Yields of byproduct given;
In water at 28℃; for 96h; Aspergillus niger, culture broth; Yield given;
(-)-3-Hydroxy-2,5-dioxo-1,1,3-trimethyl-cyclohexan

(-)-3-Hydroxy-2,5-dioxo-1,1,3-trimethyl-cyclohexan

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With sulfuric acid
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

3-formyl-5,5-dimethyl-2-cycolohexen-1-one
56621-35-3

3-formyl-5,5-dimethyl-2-cycolohexen-1-one

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With methanesulfonic acid; oxygen; molybdovanadophosphate on active carbon In toluene at 80℃; under 760 Torr; for 20h; Product distribution; regioselectivity of the aerobic oxidation, effect of the pore size of supports, or without support at various temperatures;
With phosphomolybdic acid; potassium tert-butylate; oxygen In dimethyl sulfoxide at 115℃; for 8h; Product distribution; Further Variations:; Reagents; reaction time;A 1.9 % Chromat.
B 88.4 % Chromat.
With N-hydroxyphthalimide; oxygen; copper dichloride In acetonitrile at 100℃; under 9000.9 Torr; for 3h; Autoclave;
3,5,5-trimethylcyclohex-3-en-1-one
471-01-2

3,5,5-trimethylcyclohex-3-en-1-one

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

C

β-isophorone oxide

β-isophorone oxide

D

5-hydroxy-4,4,6-trimethyl-7-oxa-bicyclo[4.1.0]heptan-2-one

5-hydroxy-4,4,6-trimethyl-7-oxa-bicyclo[4.1.0]heptan-2-one

Conditions
ConditionsYield
With tert.-butylhydroperoxide; silica gel; titanium(IV) oxide In ethylbenzene at 79.85℃; for 0.208333h; Product distribution; Further Variations:; Catalysts; time; Isomerization; oxidation;
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

CuSO4 *5H2 O

CuSO4 *5H2 O

H3 [P(Mo3 O10)4 ]*H2 O

H3 [P(Mo3 O10)4 ]*H2 O

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
MoO3 In hexane; toluene
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

isophorone oxide
10276-21-8

isophorone oxide

B

3-formyl-5,5-dimethyl-2-cycolohexen-1-one
56621-35-3

3-formyl-5,5-dimethyl-2-cycolohexen-1-one

C

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen; copper(II) sulfate In acetonitrile at 75℃; under 9000.9 Torr; for 5h; Autoclave;
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

isophorone oxide
10276-21-8

isophorone oxide

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen; calcium chloride In acetonitrile at 75℃; under 9000.9 Torr; for 5h; Autoclave;
With N-hydroxyphthalimide; oxygen In acetonitrile at 110℃; under 9000.9 Torr; for 5h; Catalytic behavior; Temperature; Time; Concentration;
(S)-4-hydroxy-3,5,5-trimethyl-4-[(3E,5E,7E,9E,11E,13E,15E)-3,7,12,16-tetramethyl-2-oxo-18-((R)-2,6,6-trimethyl-4-(triethylsilyloxy)cyclohex-1-en-1-yl)octadeca-3,5,7,9,11,13,15-heptaen-17-yn-1-yl]cyclohex-2-enone

(S)-4-hydroxy-3,5,5-trimethyl-4-[(3E,5E,7E,9E,11E,13E,15E)-3,7,12,16-tetramethyl-2-oxo-18-((R)-2,6,6-trimethyl-4-(triethylsilyloxy)cyclohex-1-en-1-yl)octadeca-3,5,7,9,11,13,15-heptaen-17-yn-1-yl]cyclohex-2-enone

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

(all-E)-(3R)-Triophaxanthin

(all-E)-(3R)-Triophaxanthin

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride Inert atmosphere;
3,5,5-trimethylcyclohex-3-en-1-one
471-01-2

3,5,5-trimethylcyclohex-3-en-1-one

A

3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With pyridine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen at 70℃; for 12h; Reagent/catalyst;
With pyridine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen at 70℃; for 12h;
3,5,5-trimethylcyclohex-3-en-1-one
471-01-2

3,5,5-trimethylcyclohex-3-en-1-one

A

2-hydroxy-4,4,6-trimethylcyclohexa-2,5-diene-1-one
28750-52-9

2-hydroxy-4,4,6-trimethylcyclohexa-2,5-diene-1-one

B

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

C

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

Conditions
ConditionsYield
With water; oxygen; triethylamine; acetylacetone In acetone at 21℃; for 18h; Kinetics; Catalytic behavior; Reagent/catalyst; Temperature; Solvent; Overall yield = 65.4 %;
3,5,5-trimethylcyclohex-3-en-1-one
471-01-2

3,5,5-trimethylcyclohex-3-en-1-one

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

Conditions
ConditionsYield
With pyridine; iron(III)-acetylacetonate; oxygen at 59.99℃; under 760.201 Torr; Kinetics; Activation energy; Temperature; Pressure; Inert atmosphere;
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

isophorone oxide
10276-21-8

isophorone oxide

B

3-formyl-5,5-dimethyl-2-cycolohexen-1-one
56621-35-3

3-formyl-5,5-dimethyl-2-cycolohexen-1-one

C

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

D

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

Conditions
ConditionsYield
With tert.-butylhydroperoxide; cetyltrimethylammonim bromide; L-proline; copper dichloride In water at 80℃; for 24h; Reagent/catalyst;
With tert.-butylhydroperoxide; N-hydroxyphthalimide; Cu3Al(OH)2(7+)*3.5CO3(2-) In acetonitrile at 90℃; for 24h; Catalytic behavior; Reagent/catalyst; Temperature;
4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

Conditions
ConditionsYield
With Cm-ADH10 at 40℃; for 6h; Enzymatic reaction;46 mg
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

C

3-(hydroxymethyl)-5,5-dimethylcyclohex-2-en-1-one

3-(hydroxymethyl)-5,5-dimethylcyclohex-2-en-1-one

D

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

Conditions
ConditionsYield
With perfluorodecanoic acid; CYP102A1 from Bacillus megaterium; oxygen; NADPH; bovine liver catalase In dimethyl sulfoxide at 30℃; for 20h; pH=7.4; Kinetics; Reagent/catalyst; Enzymatic reaction; stereoselective reaction;
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

C

3-(hydroxymethyl)-5,5-dimethylcyclohex-2-en-1-one

3-(hydroxymethyl)-5,5-dimethylcyclohex-2-en-1-one

Conditions
ConditionsYield
Stage #1: 3,5,5-Trimethylcyclohex-2-en-1-one With sodium hydroxide In water at 0 - 2℃; for 0.166667h;
Stage #2: With dihydrogen peroxide In water at 0 - 2℃; for 6h;
A n/a
B 12 mg
C n/a
3,5,5-Trimethylcyclohex-2-en-1-one
78-59-1

3,5,5-Trimethylcyclohex-2-en-1-one

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

C

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

Conditions
ConditionsYield
With Peroxygenase from Chaetomium globosum; dihydrogen peroxide In aq. phosphate buffer at 30℃; for 0.5h; pH=7; Catalytic behavior; Kinetics; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
C n/a
4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone
14203-59-9

4-hydroxy-3,5,5-trimethyl-cyclohex-2-enone

A

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

B

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

4-hydroxy-3,5,5-trimethyl-2-cyclohexen-1-one

Conditions
ConditionsYield
With Peroxygenase from Chaetomium globosum; dihydrogen peroxide In aq. phosphate buffer at 30℃; for 1h; pH=7; Catalytic behavior; Reagent/catalyst; Resolution of racemate; Enzymatic reaction; enantioselective reaction;
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

acrylonitrile
107-13-1

acrylonitrile

(1R,2R,4S)-1,5,5-Trimethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carbonitrile

(1R,2R,4S)-1,5,5-Trimethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carbonitrile

Conditions
ConditionsYield
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; N-methylaminopropylated silica gel In tetrahydrofuran; hexane at -70 - 20℃; Michael reaction;100%
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide In tetrahydrofuran; hexane at -50℃; for 0.333333h;
Stage #2: acrylonitrile In tetrahydrofuran; hexane at -50 - 20℃; for 3h;
99%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

2,6,6-trimethyl-1,4-cyclohexanedione
20547-99-3

2,6,6-trimethyl-1,4-cyclohexanedione

Conditions
ConditionsYield
With phenylsilane; isopropyl alcohol; Mn(dpm)3 at 23℃;99%
With triethanolamine; [RuII(2,2′-bipyrazyl)2(4,4′-dichloro-2,2′-bipyridyl)]Cl2; thermophilic Old Yellow Enzyme; paraquat dichloride In ethanol; water at 20℃; for 4h; pH=8; Reagent/catalyst; Solvent; Time; pH-value; UV-irradiation;88%
With acetic acid; zinc
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

trans (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone
20548-02-1

trans (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone

Conditions
ConditionsYield
With hydrogen; Ra-Ni In methanol at 25℃; under 825.07 Torr; for 8h;98.1%
With hydrogen; Raney/Ni In ethanol at 20℃; under 5171.62 Torr; for 72h;
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

ethylene glycol
107-21-1

ethylene glycol

7,9,9-trimethyl-1,4-dioxa-spiro[4.5]dec-6-en-8-one
14203-64-6

7,9,9-trimethyl-1,4-dioxa-spiro[4.5]dec-6-en-8-one

Conditions
ConditionsYield
With phenylphosphonate In benzene for 24h;96.7%
With toluene-4-sulfonic acid; trimethyl orthoformate In dichloromethane for 4h; Heating;87%
With toluene-4-sulfonic acid In benzene for 10h; Heating;73%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

acetic anhydride
108-24-7

acetic anhydride

2,3,5-trimethyl-1,4-hydroquinone diacetate
7479-28-9

2,3,5-trimethyl-1,4-hydroquinone diacetate

Conditions
ConditionsYield
at 60℃; for 9h; Temperature; Molecular sieve;96.5%
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione; acetic anhydride; methanetrisulfonic acid at 25 - 100℃; for 3.5 - 24h;
Stage #2: With sodium carbonate at 20℃; Product distribution / selectivity;
0%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

trimethyl orthoformate
149-73-5

trimethyl orthoformate

4-Methoxy-2,6,6-trimethyl-cyclohexa-2,4-dienone

4-Methoxy-2,6,6-trimethyl-cyclohexa-2,4-dienone

Conditions
ConditionsYield
With hydrogenchloride In methanol Heating;95%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

propynoic acid ethyl ester
623-47-2

propynoic acid ethyl ester

ethyl 3-(1′-hydroxy-3′,5′,5′-trimethyl-4′-oxocyclohex-2′-en-1′-yl)propiolate

ethyl 3-(1′-hydroxy-3′,5′,5′-trimethyl-4′-oxocyclohex-2′-en-1′-yl)propiolate

Conditions
ConditionsYield
Stage #1: propynoic acid ethyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6,6-trimethyl-2-cyclohexene-1,4-dione In tetrahydrofuran at -78 - 20℃; for 2.5h; Inert atmosphere; regioselective reaction;
95%
(R,R)-2,3-butandiol
24347-58-8

(R,R)-2,3-butandiol

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

(2R,3R)-2,3,7,9,9-pentamethyl-1,4-dioxaspiro[4.5]dec-6-en-8-one
917878-27-4

(2R,3R)-2,3,7,9,9-pentamethyl-1,4-dioxaspiro[4.5]dec-6-en-8-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Heating;94%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

phenylacetylene
536-74-3

phenylacetylene

4-hydroxy-2,6,6-trimethyl-4-(phenylethynyl)cyclohex-2-enone

4-hydroxy-2,6,6-trimethyl-4-(phenylethynyl)cyclohex-2-enone

Conditions
ConditionsYield
Stage #1: phenylacetylene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6,6-trimethyl-2-cyclohexene-1,4-dione In tetrahydrofuran at -78 - 20℃; for 2.5h; Inert atmosphere; regioselective reaction;
94%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

(+/-)-4-hydroxy-2,6,6-trimethyl-2-cyclohexenone
19620-37-2

(+/-)-4-hydroxy-2,6,6-trimethyl-2-cyclohexenone

Conditions
ConditionsYield
With aluminum isopropoxide In cyclohexane for 5h; Heating;93.2%
With C29H34BNOP2Ru In dichloromethane; isopropyl alcohol Schlenk technique; Inert atmosphere; Reflux;84%
With sodium tetrahydroborate; cerium(III) chloride66%
2,2-dimethyl-3-butyne
917-92-0

2,2-dimethyl-3-butyne

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

4-(3′,3′-dimethylbut-1′-yn-1′-yl)-4-hydroxy-2,6,6-trimethylcyclohex-2-enone

4-(3′,3′-dimethylbut-1′-yn-1′-yl)-4-hydroxy-2,6,6-trimethylcyclohex-2-enone

Conditions
ConditionsYield
Stage #1: 3,3-Dimethylbut-1-yne With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6,6-trimethyl-2-cyclohexene-1,4-dione In tetrahydrofuran at -78 - 20℃; for 2.5h; Inert atmosphere; regioselective reaction;
93%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

acetic anhydride
108-24-7

acetic anhydride

4-acetoxy-2,6,6-trimethylcyclohexa-2,4-dienone
124743-97-1

4-acetoxy-2,6,6-trimethylcyclohexa-2,4-dienone

Conditions
ConditionsYield
With 2-(Dimethylamino)pyridine; triethylamine at 48℃; for 17h;92.6%
With TEA
With dmap; triethylamine
cyclohexyl acrylate
3066-71-5

cyclohexyl acrylate

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

(1S,2S,4R)-1,5,5-Trimethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carboxylic acid cyclohexyl ester

(1S,2S,4R)-1,5,5-Trimethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carboxylic acid cyclohexyl ester

Conditions
ConditionsYield
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide In tetrahydrofuran; hexane at -50℃; for 0.333333h;
Stage #2: cyclohexyl acrylate In tetrahydrofuran; hexane at -50 - 20℃; for 7h;
92%
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; N-methylaminopropylated silica gel In tetrahydrofuran; hexane at -70 - 20℃; for 18h; Product distribution; Further Variations:; Reagents; Michael reaction;90%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

(-)-8-phenylmenthyl acrylate
72526-00-2

(-)-8-phenylmenthyl acrylate

A

(2S,1R,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1S,2S)-1,5,5-trimethyl-6,8-dioxobicyclo[2.2.2]octane-2-carboxylate
946149-26-4

(2S,1R,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (1S,2S)-1,5,5-trimethyl-6,8-dioxobicyclo[2.2.2]octane-2-carboxylate

B

(2S,1R,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl 1,5,5-trimethyl-6,8-dioxobicyclo[2.2.2]octane-2-carboxylate

(2S,1R,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl 1,5,5-trimethyl-6,8-dioxobicyclo[2.2.2]octane-2-carboxylate

Conditions
ConditionsYield
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With lithium diisopropyl amide In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #2: (-)-8-phenylmenthyl acrylate With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran; hexane at -40℃; for 14h; Further stages.;
A 92%
B 4%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

propynoic acid methyl ester
922-67-8

propynoic acid methyl ester

methyl 3-(1′-hydroxy-3′,5′,5′-trimethyl-4′-oxocyclohex-2′-en-1′-yl)propiolate

methyl 3-(1′-hydroxy-3′,5′,5′-trimethyl-4′-oxocyclohex-2′-en-1′-yl)propiolate

Conditions
ConditionsYield
Stage #1: propynoic acid methyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6,6-trimethyl-2-cyclohexene-1,4-dione In tetrahydrofuran at -78 - 20℃; for 2.5h; Inert atmosphere; regioselective reaction;
92%
(2S,3S)-butane-2,3-diol
19132-06-0

(2S,3S)-butane-2,3-diol

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

(2S,3S)-2,3,7,9,9-pentamethyl-1,4-dioxaspiro<4.5>dec-6-en-8-one
141245-61-6

(2S,3S)-2,3,7,9,9-pentamethyl-1,4-dioxaspiro<4.5>dec-6-en-8-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 4h; Heating;91%
With toluene-4-sulfonic acid In toluene for 24h; Heating;91%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

4-hydroxy-2,6,6-trimethyl-4-((trimethylsilyl)ethynyl)cyclohex-2-enone

4-hydroxy-2,6,6-trimethyl-4-((trimethylsilyl)ethynyl)cyclohex-2-enone

Conditions
ConditionsYield
Stage #1: trimethylsilylacetylene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6,6-trimethyl-2-cyclohexene-1,4-dione In tetrahydrofuran at -78 - 20℃; for 2.5h; Inert atmosphere; regioselective reaction;
91%
N,N-phenylbistrifluoromethane-sulfonimide
37595-74-7

N,N-phenylbistrifluoromethane-sulfonimide

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

3,3,5-trimethyl-4-oxocyclohexa-1,5-dien-1-yl trifluoromethanesulfonate
221635-90-1

3,3,5-trimethyl-4-oxocyclohexa-1,5-dien-1-yl trifluoromethanesulfonate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at -83℃;90%
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.25h;
Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78℃; for 2h;
90%
With lithium hexamethyldisilazane In tetrahydrofuran at -78 - 20℃; for 9.33333h;88.8%
With lithium hexamethyldisilazane In tetrahydrofuran at -78 - 20℃; Inert atmosphere;88%
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With lithium diisopropyl amide In tetrahydrofuran for 2h;
Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at 20℃; for 12h; Further stages.;
85%
trimethylsilyl trifluoromethanesulfonate
27607-77-8

trimethylsilyl trifluoromethanesulfonate

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

oxophorone trimethylsilylenol ether
83020-75-1

oxophorone trimethylsilylenol ether

Conditions
ConditionsYield
With 2,3,5-trimethyl-pyridine In toluene at -40℃;90%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

(1R,2R,4S)-1,5,5-Trimethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester

(1R,2R,4S)-1,5,5-Trimethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium dibenzylamide In tetrahydrofuran; hexane at -50℃;
Stage #2: acrylic acid methyl ester In tetrahydrofuran; hexane at -50 - 20℃;
90%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

1,3,3-Trimethyl-7-oxabicyclo<4.1.0>heptan-2,5-dion
38284-11-6

1,3,3-Trimethyl-7-oxabicyclo<4.1.0>heptan-2,5-dion

Conditions
ConditionsYield
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With sodium hydrogencarbonate; sodium carbonate In water at 0 - 25℃; for 1h;
Stage #2: With dihydrogen peroxide In water for 3h;
89%
With sodium hydroxide; dihydrogen peroxide In water at 20 - 25℃; for 6h; pH 9-9.5;
Weitz-Scheffer epoxidation; Inert atmosphere;
With quinone oxidoreductase from Fragaria x ananassa, strawberry; NADPH In aq. buffer at 30℃; for 24h; pH=7.5; Reagent/catalyst;
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With sodium hydroxide In water at 0 - 2℃; for 0.166667h;
Stage #2: With dihydrogen peroxide In water at 0 - 2℃; for 6h;
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

(1S,2S,4R)-1,2,5,5-Tetramethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester

(1S,2S,4R)-1,2,5,5-Tetramethyl-6,8-dioxo-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide In tetrahydrofuran; hexane at -50℃; for 0.333333h;
Stage #2: methacrylic acid methyl ester In tetrahydrofuran; hexane at -50 - 20℃;
89%
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; N-methylaminopropylated silica gel In tetrahydrofuran; hexane at -70 - 20℃; Michael reaction;83%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

2.3-butanediol
513-85-9

2.3-butanediol

2,3,7,9,9-pentamethyl-1,4-dioxaspiro[4.5]dec-6-en-8-one
1402904-89-5

2,3,7,9,9-pentamethyl-1,4-dioxaspiro[4.5]dec-6-en-8-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid; trimethyl orthoformate at 50℃; for 7h; Inert atmosphere;88%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

4-(tert-Butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-cyclohexa-2,4-dienone

4-(tert-Butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-cyclohexa-2,4-dienone

Conditions
ConditionsYield
With 2,3,5-trimethyl-pyridine In toluene at -40℃;87%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

2-hydroxy-2,6,6-trimethyl-cyclohexane-1,4-dione

2-hydroxy-2,6,6-trimethyl-cyclohexane-1,4-dione

Conditions
ConditionsYield
Stage #1: 2,6,6-trimethyl-2-cyclohexene-1,4-dione With phenylsilane; oxygen; isopropyl alcohol; Mn(dpm)3 In 1,2-dichloro-ethane at 0 - 25℃;
Stage #2: With triethyl phosphite In 1,2-dichloro-ethane
87%
(Z)-3-methylpent-2-en-4-ynol
6153-05-5

(Z)-3-methylpent-2-en-4-ynol

2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

(Z)-4-hydroxy-4-(5′-hydroxy-3′-methylpent-3′-en-1′-yn-1′-yl)-2,6,6-trimethylcyclohex-2-enone

(Z)-4-hydroxy-4-(5′-hydroxy-3′-methylpent-3′-en-1′-yn-1′-yl)-2,6,6-trimethylcyclohex-2-enone

Conditions
ConditionsYield
Stage #1: (Z)-3-methylpent-2-en-4-ynol With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 2,6,6-trimethyl-2-cyclohexene-1,4-dione In tetrahydrofuran at -78 - 20℃; for 2.5h; Time; Inert atmosphere; regioselective reaction;
87%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

acetyl chloride
75-36-5

acetyl chloride

2,3,5-trimethyl-1,4-hydroquinone diacetate
7479-28-9

2,3,5-trimethyl-1,4-hydroquinone diacetate

Conditions
ConditionsYield
With 1-methyl-3-(3-triethoxysilanepropyl)imidazolium chloride at 100℃; for 1h;85.1%
2,6,6-trimethyl-2-cyclohexene-1,4-dione
1125-21-9

2,6,6-trimethyl-2-cyclohexene-1,4-dione

A

(4S)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone
55058-51-0

(4S)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone

B

(6R)-levodione
60046-49-3

(6R)-levodione

Conditions
ConditionsYield
With D-glucose; Saccharomyces cerevisiae (baker's yeast, Fermix(R)); oxygen In ethanol for 48h; Product distribution; Kinetics; Further Variations:; conc. of educt and reagents;A n/a
B 85%

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