We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
Cas:113-73-5
Min.Order:1 Gram
Negotiable
Type:Manufacturers
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:113-73-5
Min.Order:10 Gram
FOB Price: $146.0 / 176.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:113-73-5
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:113-73-5
Min.Order:1 Kilogram
FOB Price: $15.0 / 50.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:113-73-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGRAMICIDIN C CAS:113-73-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,
Cas:113-73-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:113-73-5
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:113-73-5
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:113-73-5
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:113-73-5
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:113-73-5
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:113-73-5
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryHigh purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Gramicidin S CAS NO.113-73-5 Application:Gramicidin S CAS NO.113-73-5
good quality, competitive price, thoughtful after sale serviceAppearance:White to Off-White Solid Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by Sea
Cyclo[(Val-Orn-(Cbz)-Leu-DPhe-Pro)2]
Gramicidin S
Conditions | Yield |
---|---|
With hydrogen; palladium In acetic acid for 4h; | 90% |
With hydrogen; palladium on activated charcoal Hydrogenolysis; | |
With hydrogen |
D-Phe-Pro-Val-Orn-Leu-D-Phe-Pro-Val-Orn-Leu
Gramicidin S
Conditions | Yield |
---|---|
at 150℃; for 4h; Inert atmosphere; Neat (no solvent); | 87% |
[Orn(Boc)2,2']gramicidin
Gramicidin S
Conditions | Yield |
---|---|
With trifluoroacetic acid In dichloromethane for 0.5h; | 78% |
With trifluoroacetic acid In dichloromethane for 1h; | |
With chlorotriisopropylsilane; trifluoroacetic acid In water for 1.5h; | |
With trifluoroacetic acid In water at 20℃; for 1h; | 57 mg |
Gramicidin S
Conditions | Yield |
---|---|
With pyridine In N,N-dimethyl-formamide at 25℃; for 24h; | 65% |
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: C70H110N12O15 With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide Stage #2: With trifluoroacetic acid | 53% |
A
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: (S)-2-[(S)-5-tert-Butoxycarbonylamino-2-((S)-2-{[(S)-1-((R)-2-tert-butoxycarbonylamino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester With trifluoroacetic acid dealkoxycarbonylation; Stage #2: With pyridine In N,N-dimethyl-formamide at 25℃; for 24h; Dimerization; cyclization; | A 38% B 15% |
Boc-D-Phe-Pro-Val-Orn(Boc)-OH
A
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: Boc-D-Phe-Pro-Val-Orn(Boc)-OH; H-Leu-oxime resin With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol Stage #2: With trifluoroacetic acid In dichloromethane for 0.5h; Stage #3: With acetic acid; N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 25℃; for 24h; | A 35% B n/a |
Conditions | Yield |
---|---|
With pyridine In N,N-dimethyl-formamide at 25℃; for 24h; Yield given. Yields of byproduct given; |
D-Phe-L-Pro
Gramicidin S
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: TentaGel-PEG-CONH-CH2CH2S-Leu-Orn-Val-Pro-D-Phe-Leu-Orn-Val-Pro-D-Phe-NH2 With 3-(N-morpholino)propanesulfonate buffer; GrsB TE at 37℃; for 3h; pH=7.0; Enzymatic reaction; Stage #2: With trifluoroacetic acid In water |
(S)-2-[(S)-5-Amino-2-((S)-2-{[(S)-1-((R)-2-amino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-methyl-butyrylamino)-pentanoylamino]-4-methyl-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester
Gramicidin S
Conditions | Yield |
---|---|
With pyridine In N,N-dimethyl-formamide at 25℃; for 24h; |
Fmoc-Val-OH
Boc-D-Phe-OH
Fmoc-Pro-OH
Fmoc-Orn(Boc)-OH
Gramicidin S
Conditions | Yield |
---|---|
Multistep reaction; |
A
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: Boc-D-Phe-Pro-Val-Orn(Boc)-Leu-D-Phe-Pro-Val-Orn(Boc)-OH; H-Leu-oxime resin With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol Stage #2: With trifluoroacetic acid In dichloromethane for 0.5h; Stage #3: With acetic acid; N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 25℃; for 24h; | A 56 % Chromat. B 15 % Chromat. |
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 2.1: HCl / dioxane / 0.5 h / 20 °C 3.1: 3.21 g / HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 4.1: hydrogen / Pd/C / methanol / 15 h 5.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 6.1: BOP; HOBt 6.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 6.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1.1: HCl / dioxane / 0.5 h / 20 °C 2.1: HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 3.1: HCl / dioxane / 0.5 h / 20 °C 4.1: 3.21 g / HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 5.1: hydrogen / Pd/C / methanol / 15 h 6.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 7.1: BOP; HOBt 7.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 7.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: 3.21 g / HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 2.1: hydrogen / Pd/C / methanol / 15 h 3.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 4.1: BOP; HOBt 4.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 4.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 2.1: BOP; HOBt 2.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 2.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: HCl / dioxane / 0.5 h / 20 °C 2.1: 3.21 g / HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 3.1: hydrogen / Pd/C / methanol / 15 h 4.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 5.1: BOP; HOBt 5.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 5.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
Boc-D-Phe-Pro-Val-Orn(Z)-OBzl
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogen / Pd/C / methanol / 15 h 2.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 3.1: BOP; HOBt 3.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 3.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 2.1: HCl / dioxane / 0.5 h / 20 °C 3.1: HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 4.1: HCl / dioxane / 0.5 h / 20 °C 5.1: 3.21 g / HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 6.1: hydrogen / Pd/C / methanol / 15 h 7.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 8.1: BOP; HOBt 8.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 8.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
H-Orn(Z)-OBzl
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 2.1: HCl / dioxane / 0.5 h / 20 °C 3.1: HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 4.1: HCl / dioxane / 0.5 h / 20 °C 5.1: 3.21 g / HOBt; EDCI / CH2Cl2 / 3 h / 0 - 20 °C 6.1: hydrogen / Pd/C / methanol / 15 h 7.1: 1.90 g / NaOH / methanol; dioxane; H2O / 15 h / 20 °C 8.1: BOP; HOBt 8.2: trifluoroacetic acid / CH2Cl2 / 0.5 h 8.3: 35 percent / iPr2NEt; acetic acid / dioxane / 24 h / 25 °C View Scheme |
C70H110N12O15
Gramicidin S
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.19 g / N-hydroxybenzotriazole hydrate; diisopropylethylamine; PyBOP / dimethylformamide / 16 h 2: 78 percent / CF3CO2H / CH2Cl2 / 0.5 h View Scheme |
Gramicidin S
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 37℃; for 21h; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: water; 3,3-dimethyldioxirane / acetone / 0.17 h / 23 °C 2: water; oxalic acid / N,N-dimethyl-formamide / 48 h / 40 °C View Scheme |
Conditions | Yield |
---|---|
With water; oxalic acid In N,N-dimethyl-formamide at 40℃; for 48h; |
C68H98N12O13
Gramicidin S
Conditions | Yield |
---|---|
With water; oxalic acid In N,N-dimethyl-formamide at 40℃; for 48h; | 3.6 mg |
1-(tert-butoxycarbonyl)-L-proline
t-Boc-L-valine
N-tert-butoxycarbonyl-L-leucine
(R)-5-(benzyloxycarbonylamino)-2-(tert-butoxycarbonylamino)pentanoic acid
Boc-D-Phe-OH
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: N-tert-butoxycarbonyl-L-leucine With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide Stage #2: With trifluoroacetic acid In dichloromethane Stage #3: 1-(tert-butoxycarbonyl)-L-proline; t-Boc-L-valine; (R)-Nδ-benzyloxycarbonyl-Nα-(tert-butoxycarbonyl)-ornithine; Boc-D-Phe-OH Further stages; |
Gramicidin S
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 6h; aminomethyl resin; | 55 mg |
Fmoc-Val-OH
Fmoc-Leu-OH
Fmoc-D-Phe-OH
(R)-Pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester
Gramicidin S
Conditions | Yield |
---|---|
Stage #1: Fmoc-D-Phe-OH With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane; N,N-dimethyl-formamide for 1.5h; Stage #2: With piperidine In N,N-dimethyl-formamide for 0.166667h; Stage #3: Fmoc-Val-OH; Fmoc-Leu-OH; (R)-Pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-Lys(pg)-OH Further stages; |
Conditions | Yield |
---|---|
With triethylamine In methanol Ambient temperature; | 83% |
Conditions | Yield |
---|---|
With potassium hydrogencarbonate In methanol for 45h; Ambient temperature; | 75% |
With potassium hydrogencarbonate In methanol Ambient temperature; | 75% |
2,5-dioxopyrrolidin-(meta-diphenylphosphino)benzoate
Gramicidin S
N,N'-(3,3'-((6R,9S,12S,15S,17aS,23R,26S,29S,32S,34aS)-6,23-dibenzyl-9,26-diisobutyl-15,32-diisopropyl-5,8,11,14,17,22,25,28,31,34-decaoxotetratriacontahydrodipyrrolo[1,2-a:1',2'-p] [1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-12,29-diyl)bis(propane-3,1-diyl))bis(3-(diphenylphosphino)benzamide)
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h; Inert atmosphere; | 48% |
Gramicidin S
N,N'-(3,3'-((6R,9S,12S,15S,17aS,23R,26S,29S,32S,34aS)-6,23-dibenzyl-9,26-diisobutyl-15,32-diisopropyl-5,8,11,14,17,22,25,28,31,34 decaoxotetratriacontahydro dipyrrolo[1,2-a:1',2'-p] [1,4,7,10,13,16,19,22,25,28] decaazacyclotriacontine-12,29-diyl)bis(propane-3,1-diyl))bis(4-(diphenylphosphino)benzamide)
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h; Inert atmosphere; | 48% |
Gramicidin S
2,5-dioxopyrrolidin-1-yl 2-(diphenylphosphanyl)benzoate
N,N'-(3,3'-((6R,9S,12S,15S,17aS,23R,26S,29S,32S,34aS)-6,23-dibenzyl-9,26-diisobutyl-15,32-diisopropyl-5,8,11,14,17,22,25,28,31,34-decaoxotetratriacontahydrodipyrrolo[1,2-a:1',2'-p][1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-12,29-diyl)bis(propane-3,1-diyl))bis(2-(diphenylphosphino)benzamide)
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h; | 39% |
Gramicidin S
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h; Inert atmosphere; | 16.8% |
5-(4-carboxyphenyl)-10,15,20-tris(4-methylphenyl) porphyrin
Gramicidin S
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol Acylation; |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View