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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

(R)-1-phenylethanol

Cas:1517-69-7

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

(R)-(+)-1-Phenylethanol Basic information Product Name: (R)-(+)-1-Phenylethanol Synonyms: (R)-(+)-PHENYLETHANOL;(R)-(+)-SEC-PHENETHYL ALCOHOL;(R)-(+)-SEC-PHENYLETHYL ALCOHOL;(R)-(+)-1-ME

TIANFU-CHEM CAS:1517-69-7 (R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 1517-69-7 with best quality

Cas:1517-69-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:10 Kilogram

FOB Price: $80.0 / 100.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzenemethanol,a-methyl-, (aR)- 1517-69-7

Cas:1517-69-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: (R)-(+)-1-Phenylethanol MF: C8H10O MW: 122.16 EINECS: 604-814-2 (R)-(+)-1-Phenylethanol Structure (R)-(+)-1-Phenylethanol Chemical Properties Melting point 9-11 °C (lit.) alpha 42.5 º (NEAT) Boiling point

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

(R)-(+)-1-Phenylethanol CAS:1517-69-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

(R)-(+)-1-Phenylethanol CAS:1517-69-7

Cas:1517-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzenemethanol,a-methyl-, (aR)-

Cas:1517-69-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenemethanol,a-methyl-, (aR)-

Cas:1517-69-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

(R)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Gram

FOB Price: $4.84

Type:Trading Company

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Triumph International Development Limilted

Appearance:white powder/crystal Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Ai

(+)-Methyl phenyl carbinol

Cas:1517-69-7

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

(R)-(+)-1-Phenylethanolv

Cas:1517-69-7

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(R)-(+)-1-PHENYLETHANOL

Cas:1517-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(R)-1-phenylethanol

Cas:1517-69-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Appearance/Colour:Colorless to light yellow liquid Vapor Pressure:0.139mmHg at 25°C Melting Point:9-11 °C(lit.) Refractive Index:n20/D 1.528 Boiling Point:206.9 °C at 760 mmHg PKA:14.43±0.20(Predicted) Flash Point:85

1517-69-7 (R)-1-phenylethanol most cost-effective

Cas:1517-69-7

Min.Order:1 Gram

FOB Price: $6.0

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzenemethanol,a-methyl-, (aR)-

Cas:1517-69-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

best supplier of (+)-Methyl phenyl carbinol with low price CAS NO.1517-69-7Appearance:White crystalline powder Storage:Store in Cool and dry .place, keep away from incompatible substances Package:according to customers' requirements Application:healt

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

C8H10O (R)-(+)-1-Phenylethanol 1517-69-7

Cas:1517-69-7

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery Appearance:Colorless to light yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Used as Pharmaceu

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply (+)-Methyl phenyl carbinol

Cas:1517-69-7

Min.Order:0

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

C8H10O (R)-(+)-1-Phenylethanol 1517-69-7

Cas:1517-69-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(R)-(+)-1-Phenylethanol

Cas:1517-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

C8H10O (R)-(+)-1-Phenylethanol 1517-69-7

Cas:1517-69-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Synthetic route

acetophenone
98-86-2

acetophenone

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With RuBr2[(S,S)-2,4-bis(diphenylphosphino)pentane](2-aminomethyl-3,5-dimethylpyridine); potassium tert-butylate; hydrogen In ethanol at 40℃; under 7600.51 Torr; for 19h; Reagent/catalyst; Inert atmosphere; Autoclave;A 100%
B n/a
With dimethylsulfide borane complex; diphenyl-N-(3-pyridylmethyl)prolinol N-oxide In tetrahydrofuran for 5h; Heating;A n/a
B 99%
With borane-THF; (R)-1-(1'-amino-1'-phenylmethyl)cyclopentanol In tetrahydrofuran at 30℃; for 2h; Title compound not separated from byproducts;A 98%
B n/a
acetophenone
98-86-2

acetophenone

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With (S)-2-amino-1,1,3-triphenylpropan-1-ol borane In tetrahydrofuran at 30℃;100%
With dimethylsulfide borane complex; (S)-chiral amino alcohol; aluminum ethoxide In tetrahydrofuran at 20℃; Reduction;100%
With (S)-diphenylprolinol; dimethylsulfide borane complex In tetrahydrofuran at 20℃;100%
trimethylaluminum
75-24-1

trimethylaluminum

benzaldehyde
100-52-7

benzaldehyde

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With titanium(IV) isopropylate; (R,S)-2-OH-3,5-Cl2-C6H2-SO2-NH-CH(CH2Ph)-CH(Ph)OH In tetrahydrofuran at 0℃; for 12h;100%
In tetrahydrofuran; hexane at -20℃; for 3h; Product distribution / selectivity;60%
acetophenone
98-86-2

acetophenone

(E)-benzalacetone
1896-62-4

(E)-benzalacetone

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With Triethoxysilane; (S,S,S,S)-N,N'-di(α-phenylethyl)cyclohexane-1,2-diamine; diethylzinc In toluene at 20℃; for 18h; Title compound not separated from byproducts.;A n/a
B 100%
With polymethylhydrosiloxane; (S,S,S,S)-N,N'-di(α-phenylethyl)cyclohexane-1,2-diamine; diethylzinc In toluene at 20℃; for 24h; Title compound not separated from byproducts.;A n/a
B 90%
(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With Candida albicans CCT 0776 In water at 30℃; for 360h; Time; Enzymatic reaction; enantioselective reaction;100%
With C48H48N2O4Ru2 In benzene at 30℃; for 20h; Irradiation; Darkness; optical yield given as %ee;99.9%
Stage #1: (S)-1-phenylethanol With azodicarboxylic acid bis(2-methoxyethyl) ester; 4-diphenylphosphanobenzoic acid In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: With water; sodium hydroxide In tetrahydrofuran at 20℃; stereospecific reaction;
90%
1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With alcohol dehydrogenase from Thermoanaerobium brockii; NADH-specific (R)-selective-ADH; YcnD-oxidoreductase at 30℃; for 6h; pH=7.5; aq. buffer; Resolution of racemate; Enzymatic reaction; optical yield given as %ee; enantiospecific reaction;99%
In water at 30℃; for 24h; Geotrichum Candidum IFQ 5767;96%
With cells of Geotrichum candidum IFO 5767 In water at 30℃; for 24h;96%
(R)-1-phenyl-1-(trichlorosilyl)ethane
38053-75-7

(R)-1-phenyl-1-(trichlorosilyl)ethane

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol for 16h;99%
With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol; water at 20℃; for 12h; enantioselective reaction;37%
With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol for 10h; Ambient temperature; Yield given;
(R)-1-phenethyl acetate
16197-92-5

(R)-1-phenethyl acetate

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With water; potassium carbonate In methanol at 20℃; optical yield given as %ee;99%
With methanol; sodium hydroxide for 1h;99%
With methanol; oxo[hexa(trifluoroacetato)]tetrazinc for 18h; Reflux; Inert atmosphere;98%
dimethyl zinc(II)
544-97-8

dimethyl zinc(II)

benzaldehyde
100-52-7

benzaldehyde

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With titanium(IV) isopropylate In hexane at -35℃; for 3h;99%
Stage #1: dimethyl zinc(II) With (1S,2S,4R)-1,3,3-trimethyl-2-[(R)-2-(6-phenylpyridin-2-yl)phenyl]bicyclo-[2.2.1]heptan-2-ol In toluene at 0 - 20℃; Inert atmosphere;
Stage #2: benzaldehyde In toluene at 0℃; for 96h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;
99%
Stage #1: dimethyl zinc(II); benzaldehyde With (2R,3S,3aS,4aR,6R,8aS)-2-isopropyl-6,9,9-trimethyl-3-phenyldecahydro-4aH-pyrrolo[2,1-b][1,3]benzoxazin-3-ol In hexane; toluene at -20 - 20℃; for 30h; Inert atmosphere;
Stage #2: With ammonium chloride In hexane; water; toluene Inert atmosphere; optical yield given as %ee; enantioselective reaction;
96%
(S)-1-tert-butyl 3-((R)-1-phenylethyl) 2-methyl-2-allylmalonate
1440524-56-0

(S)-1-tert-butyl 3-((R)-1-phenylethyl) 2-methyl-2-allylmalonate

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

(S)-2-((tert-butoxy)carbonyl)-2-methylpent-4-enoic acid
1440524-79-7

(S)-2-((tert-butoxy)carbonyl)-2-methylpent-4-enoic acid

Conditions
ConditionsYield
With water; potassium hydroxide In methanol at 20℃; for 24h;A n/a
B 98%
α-bromoacetophenone
70-11-1

α-bromoacetophenone

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

(S)-2-bromo-1-phenylethanol
2425-28-7, 73908-23-3, 74497-33-9, 76155-80-1

(S)-2-bromo-1-phenylethanol

Conditions
ConditionsYield
With sodium formate; cetyltrimethylammonim bromide; sodium dodecyl-sulfate; (R,R)-TsDPEN; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer In water at 28℃; for 1h;A 3 % Spectr.
B 97%
phenylacetylene
536-74-3

phenylacetylene

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
Stage #1: phenylacetylene With chloro(1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene)gold(I); water In methanol at 110℃; for 6h;
Stage #2: With C26H26ClN2O2RhS; water; sodium formate In methanol at 30℃; for 5h;
97%
Stage #1: phenylacetylene With formic acid at 100℃; for 0.5h; Inert atmosphere; Sealed tube;
Stage #2: With pentamethylcyclopentadienyl*RhCl[(S,S)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine]; water; sodium hydroxide at 20 - 40℃; for 3h; pH=7; enantioselective reaction;
87%
With iron(III) chloride; sodium formate In water at 40℃; for 24h; optical yield given as %ee;86%
C8H10O4S*CH5N3

C8H10O4S*CH5N3

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With water In tetrahydrofuran for 12h; Reagent/catalyst; Reflux;97%
(R,R)-(-)-1,6-bis(o-chlorophenyl)-1,6-diphenylhexa-2,4-diyne-1,6-diol
86436-19-3

(R,R)-(-)-1,6-bis(o-chlorophenyl)-1,6-diphenylhexa-2,4-diyne-1,6-diol

acetophenone
98-86-2

acetophenone

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With 1,2-diaminoethane-bisborane In solid Product distribution; enantioselective reduction of var. ketones in optically active host compounds with a BH3-ethylenediamine complex in the solid state;A n/a
B 96%
methyltriisopropoxytitanium(IV)
18006-13-8

methyltriisopropoxytitanium(IV)

benzaldehyde
100-52-7

benzaldehyde

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With (Sa)-2'-((S)-hydroxy(phenyl)methyl)-[1,1'-binaphthalen]-2-ol In tetrahydrofuran; diethyl ether at 0℃; for 1.5h; Catalytic behavior; Solvent; Temperature; enantioselective reaction;96%
1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

4-chlorophenyl acetate
876-27-7

4-chlorophenyl acetate

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

C

(R)-1-phenethyl acetate
16197-92-5

(R)-1-phenethyl acetate

Conditions
ConditionsYield
With Novozym 435; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl In toluene at 25℃; for 42h;A n/a
B n/a
C 95%
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; potassium tert-butylate; sodium carbonate In toluene at 60℃; for 48h; Inert atmosphere; Schlenk technique; Enzymatic reaction; Overall yield = 70 %Spectr.; Optical yield = 40 %ee; enantioselective reaction;
(R)-1-phenylethyl diphenylacetate

(R)-1-phenylethyl diphenylacetate

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; methanol at 0 - 20℃; for 1.5h;94%
benzyl (+/-)-cis-(2-aminocyclopentyl)carbamate

benzyl (+/-)-cis-(2-aminocyclopentyl)carbamate

1-phenylethyl acetate
93-92-5, 50373-55-2

1-phenylethyl acetate

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

benzyl (1S,2R)-[(2-acetylamino)cyclopentyl]carbamate
1240201-04-0

benzyl (1S,2R)-[(2-acetylamino)cyclopentyl]carbamate

Conditions
ConditionsYield
With triethylamine In tert-butyl methyl ether at 50℃; for 216h; Inert atmosphere; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;A n/a
B 94%
ethylbenzene
100-41-4

ethylbenzene

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

acetophenone
98-86-2

acetophenone

Conditions
ConditionsYield
With Aspergillus niger MTCC-404 at 35℃; for 24h; aq. phosphate buffer; Microbiological reaction; Closed tube; optical yield given as %ee;A 93%
B n/a
Stage #1: ethylbenzene With 1-(tert-butoxycarbonyl)-L-proline; [(2R,2’R)-1,1’-bis((3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)-2,2’-bipyrrolidineMnII(OTf)2]; dihydrogen peroxide at -40℃;
Stage #2: In acetonitrile enantioselective reaction;
A 39%
B n/a
With calcium sulfite; recombinant peroxygenase from Agrocybe aegerita; sulfite oxidase from Arabidopsis thaliana In aq. phosphate buffer at 30℃; pH=7; Catalytic behavior; Enzymatic reaction; enantioselective reaction;A 155 mg
B 23%
1-phenylethyl propanoate
120-45-6

1-phenylethyl propanoate

2-heptylamine
123-82-0

2-heptylamine

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

(R)-N-(heptan-2-yl)propionamide

(R)-N-(heptan-2-yl)propionamide

C

(R)-1-phenylethyl propionate
107832-32-6

(R)-1-phenylethyl propionate

D

(S)-1-phenylethyl propionate
120-45-6, 107832-32-6, 117405-47-7, 117290-46-7

(S)-1-phenylethyl propionate

Conditions
ConditionsYield
With hydrogen; lipase B from Candida antarctica In toluene at 70℃; under 750.075 Torr; for 48h; Resolution of racemate; Enzymatic reaction;A 47%
B 93%
C n/a
D n/a
1-phenylethyl propanoate
120-45-6

1-phenylethyl propanoate

2-heptylamine
123-82-0

2-heptylamine

A

(R)-2-methoxy-N-(octan-2-yl)acetamide

(R)-2-methoxy-N-(octan-2-yl)acetamide

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

C

(R)-1-phenylethyl propionate
107832-32-6

(R)-1-phenylethyl propionate

D

(S)-1-phenylethyl propionate
120-45-6, 107832-32-6, 117405-47-7, 117290-46-7

(S)-1-phenylethyl propionate

Conditions
ConditionsYield
With hydrogen; lipase B from Candida antarctica In toluene at 70℃; under 750.075 Torr; for 48h; Resolution of racemate; Enzymatic reaction;A 93%
B 47%
C n/a
D n/a
1-phenylethyl propanoate
120-45-6

1-phenylethyl propanoate

RS-mexiletine
31828-71-4

RS-mexiletine

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

C14H21NO2

C14H21NO2

C

(S)-1-phenylethyl propionate
120-45-6, 107832-32-6, 117405-47-7, 117290-46-7

(S)-1-phenylethyl propionate

Conditions
ConditionsYield
With hydrogen; lipase B from Candida antarctica In toluene at 70℃; under 750.075 Torr; for 48h; Resolution of racemate; Enzymatic reaction;A 46%
B 93%
C n/a
Isopropenyl acetate
108-22-5

Isopropenyl acetate

1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

C

(R)-1-phenethyl acetate
16197-92-5

(R)-1-phenethyl acetate

Conditions
ConditionsYield
With Candida antarctica lipase B; dicarbonyl(chloro)(η5-pentaphenylcyclopentadienyl)ruthenium(II); potassium tert-butylate; sodium carbonate In tetrahydrofuran; toluene at 20℃; for 3h;A n/a
B n/a
C 92%
With Pseudomonas cepacia lipase In diethyl ether at 40℃; for 24h; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
C 9%
With Novozym 435; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl In toluene at 25℃; for 30h; Product distribution; Further Variations:; Reagents; Solvents; reaction times;
bis(trimethylaluminum)–1,4-diazabicyclo[2.2.2]octane adduct
137203-34-0

bis(trimethylaluminum)–1,4-diazabicyclo[2.2.2]octane adduct

benzaldehyde
100-52-7

benzaldehyde

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
In tetrahydrofuran at 5℃; for 1h; Product distribution / selectivity;92%
1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With (S,S)-2,3-O-isopropylidene-1,1,4,4-tetraphenylthreitol In hexane at 20℃; for 72h;A n/a
B 90%
With Candida antarctica lipase B; 1-(10-carboxydecyl)-3-methylimidazolium hexafluorophosphate; diisopropyl-carbodiimide In acetone at 40℃; for 14h; Catalytic behavior; Reagent/catalyst; Temperature; Concentration; Resolution of racemate; Enzymatic reaction; enantioselective reaction;A 51%
B 32%
Stage #1: 1-Phenylethanol With Novozym 435(R); 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 35℃; under 100 Torr; for 96h;
Stage #2: With ethanol at 35℃; for 24h; Further stages.;
A n/a
B 22.5%
<2S-(2α(S*),3aα,4α,7α,7aα)>-2,3,3a,4,5,6,7,7a-Octahydro-7,8,8-trimethyl-2-(1-phenylethoxy)-4,7-methanobenzofuran
81978-44-1

<2S-(2α(S*),3aα,4α,7α,7aα)>-2,3,3a,4,5,6,7,7a-Octahydro-7,8,8-trimethyl-2-(1-phenylethoxy)-4,7-methanobenzofuran

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With toluene-4-sulfonic acid; triethylamine In methanol for 1h; Ambient temperature;90%
1-styrenyloxytrimethylsilane
13735-81-4

1-styrenyloxytrimethylsilane

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
Stage #1: 1-styrenyloxytrimethylsilane With tri-tert-butyl phosphine; C52H54; hydrogen; bis(pentafluorophenyl)borohydride In 1,3,5-trimethyl-benzene; pentane at 50℃; under 30003 Torr; for 24h; Inert atmosphere; Sealed tube;
Stage #2: With tetrabutyl ammonium fluoride In tetrahydrofuran; 1,3,5-trimethyl-benzene; pentane at 20℃; for 1h; Reagent/catalyst; Concentration; Solvent; enantioselective reaction;
90%
Multi-step reaction with 2 steps
1: C52H58; tri-tert-butyl phosphine; hydrogen / hexane / 24 h / 30003 Torr
2: tetrabutyl ammonium fluoride / toluene; pentane; tetrahydrofuran / 0.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: bis(pentafluorophenyl)borohydride; C52H58; tri-tert-butyl phosphine; hydrogen / toluene; pentane / 24 h / 50 °C / 30003 Torr / Autoclave
2: tetrabutyl ammonium fluoride / toluene; pentane; tetrahydrofuran / 0.5 h / 20 °C
View Scheme
methyllithium
917-54-4

methyllithium

benzaldehyde
100-52-7

benzaldehyde

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Conditions
ConditionsYield
With triisopropoxytitanium(IV) chloride; (Sa)-2'-((S)-hydroxy(phenyl)methyl)-[1,1'-binaphthalen]-2-ol In diethyl ether; hexane at -20℃; for 0.166667h; Reagent/catalyst; enantioselective reaction;90%
1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

A

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

B

acetophenone
98-86-2

acetophenone

Conditions
ConditionsYield
With Candida albicans CCT 0776 In water at 30℃; for 144h; Time; Resolution of racemate; Enzymatic reaction; enantioselective reaction;A 89%
B 11%
With Sphingomonas paucimobilis NCIMB 8195 In water; N,N-dimethyl-formamide for 144h;A 81%
B 14%
With Candida albicans CCT 0776 whole cells at 28℃; for 2.5h; pH=7; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee;A 48%
B 50%
vinyl acetate
108-05-4

vinyl acetate

1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

A

(S)-1-phenylethanol
1445-91-6

(S)-1-phenylethanol

B

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

C

(R)-1-phenethyl acetate
16197-92-5

(R)-1-phenethyl acetate

Conditions
ConditionsYield
With Novozym 435; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl In toluene at 25℃; for 96h;A n/a
B n/a
C 89%
With lipase PS from Burkholderia cepacia at 35℃; Ionic liquid; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 58%
With IL1; Lipase PS-C In di-isopropyl ether at 35℃; for 2h; Product distribution; Enzyme kinetics; Kinetics; Further Variations:; Reagents; time;A n/a
B n/a
C 39%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

(S)-chlorofluoroacetic acid
25197-75-5

(S)-chlorofluoroacetic acid

(S)-Chloro-fluoro-acetic acid (R)-1-phenyl-ethyl ester

(S)-Chloro-fluoro-acetic acid (R)-1-phenyl-ethyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; Esterification;100%
2,3-dihydro-2H-furan
1191-99-7

2,3-dihydro-2H-furan

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

(S)-2-((R)-1-Phenyl-ethoxy)-tetrahydro-furan

(S)-2-((R)-1-Phenyl-ethoxy)-tetrahydro-furan

Conditions
ConditionsYield
chiral ruthenium(II)(NO+)Cl(salen) In chlorobenzene at 20℃; for 24h; Irradiation;100%
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

(R)-1-phenylethyl acetoacetate
123261-65-4

(R)-1-phenylethyl acetoacetate

Conditions
ConditionsYield
With dmap In tetrahydrofuran at 20℃;100%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

C11H8ClFO2

C11H8ClFO2

(1R,4S)-((R)-1-phenylethyl) 8-fluoro-1,2,3,4-tetrahydro-1,4-epoxynaphthalene-1-carboxylate

(1R,4S)-((R)-1-phenylethyl) 8-fluoro-1,2,3,4-tetrahydro-1,4-epoxynaphthalene-1-carboxylate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃;99%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

(S)-(1-chloroethyl)benzene
3756-41-0

(S)-(1-chloroethyl)benzene

Conditions
ConditionsYield
With oxalyl dichloride; 2,3-bis(4-methoxyphenyl)cyclopropenone In dichloromethane at 30℃; for 1h; Inert atmosphere; optical yield given as %ee;98%
With thionyl chloride In dichloromethane at 0 - 50℃; for 3h; Inert atmosphere;66%
With thionyl chloride In dichloromethane at 0 - 50℃; Inert atmosphere;66%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

bromoacetic acid
79-08-3

bromoacetic acid

(R)-methylbenzyloxyacetic acid
287400-47-9

(R)-methylbenzyloxyacetic acid

Conditions
ConditionsYield
With potassium hydride In tetrahydrofuran for 20h; Alkylation; Heating;98%
5-methyl-1,10-phenanthroline
3002-78-6

5-methyl-1,10-phenanthroline

3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

3-(R-1-phenylethoxy)anisole

3-(R-1-phenylethoxy)anisole

Conditions
ConditionsYield
With CuI; caesium carbonate In toluene98%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

N,N-Dimethylthiocarbamoyl chloride
16420-13-6

N,N-Dimethylthiocarbamoyl chloride

(R)-O-(1-phenylethyl) N,N-dimethylthiocarbamate

(R)-O-(1-phenylethyl) N,N-dimethylthiocarbamate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; mineral oil at 25℃; for 1h; Inert atmosphere;98%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Ethyl oxalyl chloride
4755-77-5

Ethyl oxalyl chloride

ethyl (R)-1-phenylethyl oxalate
890048-81-4

ethyl (R)-1-phenylethyl oxalate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃;97%
With pyridine In dichloromethane at 20℃;97%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

Methacryloyl chloride
920-46-7

Methacryloyl chloride

(R)-α-methylbenzyl methacrylate
17199-94-9

(R)-α-methylbenzyl methacrylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 6h; Inert atmosphere;97%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

C20H17ClO3

C20H17ClO3

C28H26O4

C28H26O4

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 24h;97%
(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

(R)-1-phenylethyl 1H-imidazole-1-carboxylate
1247028-03-0

(R)-1-phenylethyl 1H-imidazole-1-carboxylate

Conditions
ConditionsYield
In ethyl acetate for 20h; Reflux; Inert atmosphere;96%
In ethyl acetate for 20h; Inert atmosphere; Reflux;96%
In dichloromethane at 0 - 20℃; for 17h; Inert atmosphere;90%
In dichloromethane at 20℃; for 0.5h;
4-bromo-2-methyl-benzoic acid tert-butyl ester
445003-37-2

4-bromo-2-methyl-benzoic acid tert-butyl ester

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

tert-butyl 3-methyl-2'-[(1R)-1-hydroxyethyl]biphenyl-4-carboxylate
1246560-92-8

tert-butyl 3-methyl-2'-[(1R)-1-hydroxyethyl]biphenyl-4-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-1-phenylethanol With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In hexane at 50℃; for 1h; Cooling with ice; Inert atmosphere;
Stage #2: With Triisopropyl borate In hexane at 20 - 40℃; for 2h; Inert atmosphere;
Stage #3: 4-bromo-2-methyl-benzoic acid tert-butyl ester With potassium phosphate; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; water at 20 - 65℃; for 2.5h; Suzuki Coupling; Inert atmosphere;
95.5%
3-ethoxy-2-methylacrolein
62055-46-3

3-ethoxy-2-methylacrolein

(R)-1-phenylethanol
1517-69-7

(R)-1-phenylethanol

(E)-(1'R)-2-Methyl-3-(1'-phenylethoxy)-propenal
130814-73-2

(E)-(1'R)-2-Methyl-3-(1'-phenylethoxy)-propenal

Conditions
ConditionsYield
With toluene-4-sulfonic acid under 1 Torr;95%
With toluene-4-sulfonic acid under 0.05 Torr; for 3h; Ambient temperature;93%

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