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Hangzhou Think Chemical Co. Ltd

Name 4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol Molecular Formula C15H13N3S Molecular Weight 267

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Shanghai SE Pharm Co., Ltd

1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99.0% Appearan

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 1533519-84-4 with best quality

Cas:1533519-84-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione 1533519-84-4

Cas:1533519-84-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione CAS: 1533519-84-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermedia

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione CAS: 1533519-84-4

Cas:1533519-84-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Lesinurad intermediate 1533519-84-4

Cas:1533519-84-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-CYCLOPROPYL-1-NAPHTHALENAMINE

Cas:1533519-84-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione/High quality/Best price

Cas:1533519-84-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFUCHEM--1533519-84-4--4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione CAS No.:1533519-84-4 Molecule Formula:C15H13N3S Molecule Weight:267.35 Purity: 98.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:E

High Quality 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione on stock

Cas:1533519-84-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-(4-cyclopropylnaphthalen-1-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione

Cas:1533519-84-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thioneCAS NO.: 1533519-84-4

Cas:1533519-84-4

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1533519-84-4 LESINURAD INTERMEDIA / high quality /Best price/In stock

Cas:1533519-84-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Cas:1533519-84-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1533519-84-4 LESINURAD INTERMEDIA / high quality /Best price/In stock

Cas:1533519-84-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

4-(4-cyclopropylnaphthalen-1-yl)-4h-1,2,4-triazole-3-thiol

Cas:1533519-84-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Synthetic route

N-(4-cyclopropylnaphthalen-1-yl)-2-formylhydrazine-1-thiocarboxamide
1533519-86-6

N-(4-cyclopropylnaphthalen-1-yl)-2-formylhydrazine-1-thiocarboxamide

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
With water; sodium hydroxide In N,N-dimethyl-formamide at 30℃; for 16h; Solvent; Temperature; Reagent/catalyst;90%
With potassium hydrogencarbonate In water; N,N-dimethyl-formamide at 90 - 140℃;
C12H8ClN3S

C12H8ClN3S

cyclopropylmagnesium bromide
23719-80-4

cyclopropylmagnesium bromide

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
In tetrahydrofuran for 2h;89.89%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 4 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide / 50 - 55 °C
4: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 3 steps
1.1: potassium carbonate / water; N,N-dimethyl-formamide / 3.5 h / 15 °C
1.2: 1 h / 0 °C
1.3: 2 h
2.1: ethyl acetate / 2 h / 60 °C
3.1: sodium hydroxide; water / N,N-dimethyl-formamide / 16 h / 30 °C
View Scheme
1-Bromonaphthalene
90-11-9

1-Bromonaphthalene

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 0 - 5 °C
2: nitric acid / 0 - 20 °C
3: palladium on activated charcoal; hydrogen
4: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
5: N,N-dimethyl-formamide / 50 - 55 °C
6: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 6 steps
1: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 0 - 5 °C
2: nitric acid / 0 - 20 °C
3: hydrazine hydrate / methanol / Reflux
4: potassium hydroxide / dichloromethane
5: N,N-dimethyl-formamide / 50 - 55 °C
6: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 7 steps
1: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 0 - 5 °C
2: nitric acid / 0 - 20 °C
3: palladium on activated charcoal; hydrogen
4: toluene; water
5: potassium hydroxide
6: N,N-dimethyl-formamide / 50 - 55 °C
7: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
1-cyclopropyl-naphthalene
25033-19-6

1-cyclopropyl-naphthalene

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: nitric acid / 0 - 20 °C
2: palladium on activated charcoal; hydrogen
3: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
4: N,N-dimethyl-formamide / 50 - 55 °C
5: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 5 steps
1: nitric acid / 0 - 20 °C
2: hydrazine hydrate / methanol / Reflux
3: potassium hydroxide / dichloromethane
4: N,N-dimethyl-formamide / 50 - 55 °C
5: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 6 steps
1: nitric acid / 0 - 20 °C
2: palladium on activated charcoal; hydrogen
3: toluene; water
4: potassium hydroxide
5: N,N-dimethyl-formamide / 50 - 55 °C
6: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
1-cyclopropyl-4-nitronaphthalene
878671-93-3

1-cyclopropyl-4-nitronaphthalene

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: palladium on activated charcoal; hydrogen
2: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
3: N,N-dimethyl-formamide / 50 - 55 °C
4: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 4 steps
1: hydrazine hydrate / methanol / Reflux
2: potassium hydroxide / dichloromethane
3: N,N-dimethyl-formamide / 50 - 55 °C
4: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 5 steps
1: palladium on activated charcoal; hydrogen
2: toluene; water
3: potassium hydroxide
4: N,N-dimethyl-formamide / 50 - 55 °C
5: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
1-amino-4-cyclopropylnaphthalene oxalate
1533519-87-7

1-amino-4-cyclopropylnaphthalene oxalate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium hydroxide
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
(1-cyclopropylnaphthalen-4-yl)isothiocyanate
878671-95-5

(1-cyclopropylnaphthalen-4-yl)isothiocyanate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide / 50 - 55 °C
2: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
Multi-step reaction with 2 steps
1: ethyl acetate / 2 h / 60 °C
2: sodium hydroxide; water / N,N-dimethyl-formamide / 16 h / 30 °C
View Scheme
1-amino-4-cyclopropylnaphthalene hydrochloride
1533519-92-4

1-amino-4-cyclopropylnaphthalene hydrochloride

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium hydroxide / dichloromethane
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
tert-butyl 4-cyclopropylnaphthalen-1-ylcarbamate
1533519-91-3

tert-butyl 4-cyclopropylnaphthalen-1-ylcarbamate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogenchloride / ethanol
2: potassium hydroxide / dichloromethane
3: N,N-dimethyl-formamide / 50 - 55 °C
4: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
View Scheme
4-Bromo-1-naphthylamine
2298-07-9

4-Bromo-1-naphthylamine

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium phosphate; palladium diacetate / toluene; water / 3 h / 110 °C / Inert atmosphere
2.1: potassium carbonate / water; N,N-dimethyl-formamide / 3.5 h / 15 °C
2.2: 1 h / 0 °C
2.3: 2 h
3.1: ethyl acetate / 2 h / 60 °C
4.1: sodium hydroxide; water / N,N-dimethyl-formamide / 16 h / 30 °C
View Scheme
C12H9N3OS

C12H9N3OS

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide / dichloromethane / 4 h / Reflux
2: tetrahydrofuran / 2 h
View Scheme
4-bromo-1-naphthol
571-57-3

4-bromo-1-naphthol

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / ethanol / 3 h / 30 °C
2: N,N-dimethyl-formamide / dichloromethane / 4 h / Reflux
3: tetrahydrofuran / 2 h
View Scheme
1,2-bis(chloroacetoxy)ethane
6941-69-1

1,2-bis(chloroacetoxy)ethane

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

ethane-1,2-diyl bis({[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate)

ethane-1,2-diyl bis({[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate)

Conditions
ConditionsYield
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 20℃; for 72h; Time;100%
With potassium hydrogencarbonate In ethanol at 50 - 55℃; Inert atmosphere;92%
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-yl)thio)acetic acid methyl ester
1533519-85-5

2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-yl)thio)acetic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 3h;99.5%
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 4h;85%
With sodium carbonate In N,N-dimethyl-formamide at 27 - 35℃; Concentration; Time; Temperature; Large scale;
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h;4 g
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h;4 g
ethane-1,2-diyl bis(2-bromoacetate)
3785-34-0

ethane-1,2-diyl bis(2-bromoacetate)

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

ethane-1,2-diyl bis({[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate)

ethane-1,2-diyl bis({[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate)

Conditions
ConditionsYield
With potassium hydrogencarbonate In ethanol at 50 - 55℃; Inert atmosphere;94%
phenyl 2-bromoacetate
620-72-4

phenyl 2-bromoacetate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

phenyl 2‐((4‐(4‐cyclopropylnaphthalen‐1‐yl)‐4H‐1,2,4‐triazol‐3‐yl)thio)acetate

phenyl 2‐((4‐(4‐cyclopropylnaphthalen‐1‐yl)‐4H‐1,2,4‐triazol‐3‐yl)thio)acetate

Conditions
ConditionsYield
Stage #1: 4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol With triethylamine In isopropyl alcohol at 20℃; for 0.333333h;
Stage #2: phenyl 2-bromoacetate In isopropyl alcohol at 0 - 20℃; for 2h;
92%
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

bromoacetic acid
79-08-3

bromoacetic acid

2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid

2-[[4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid

Conditions
ConditionsYield
Stage #1: 4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol With sodium hydrogencarbonate In ethanol; water at 25 - 45℃;
Stage #2: bromoacetic acid In ethanol; water at 25 - 55℃; for 1h;
Stage #3: With acetic acid In ethanol; water at 25 - 50℃;
91.9%
phenyl chloroacetate
620-73-5

phenyl chloroacetate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

phenyl 2‐((4‐(4‐cyclopropylnaphthalen‐1‐yl)‐4H‐1,2,4‐triazol‐3‐yl)thio)acetate

phenyl 2‐((4‐(4‐cyclopropylnaphthalen‐1‐yl)‐4H‐1,2,4‐triazol‐3‐yl)thio)acetate

Conditions
ConditionsYield
Stage #1: 4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol With triethylamine In acetone at 20℃; for 0.333333h;
Stage #2: phenyl chloroacetate In isopropyl alcohol; acetone at 0 - 20℃; for 2h;
90%
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-yl)thio)acetic acid methyl ester
1533519-85-5

2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-yl)thio)acetic acid methyl ester

Conditions
ConditionsYield
With potassium phosphate In water; acetone at 40℃; for 6h;90%
(R)-1-phenylethyl 2-bromoacetate
1046769-20-3

(R)-1-phenylethyl 2-bromoacetate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

(R)-1-phenylethyl 2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate

(R)-1-phenylethyl 2-((4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 15℃; for 3h;87%
With potassium carbonate In N,N-dimethyl-formamide at 15℃; for 2.5h;
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

chloroacetic acid 2-[2-(2-chloro-acetoxy)-ethoxy]-ethyl ester
106-78-5

chloroacetic acid 2-[2-(2-chloro-acetoxy)-ethoxy]-ethyl ester

C38H36N6O5S2

C38H36N6O5S2

Conditions
ConditionsYield
In ethanol at 50 - 55℃; Inert atmosphere;86%
chloroacetic acid 4-(2-chloroacetoxy)phenyl ester
10470-77-6

chloroacetic acid 4-(2-chloroacetoxy)phenyl ester

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

C40H32N6O4S2

C40H32N6O4S2

Conditions
ConditionsYield
In acetonitrile at 50 - 55℃; Inert atmosphere;83%
Methyl 3-bromopropionate
3395-91-3

Methyl 3-bromopropionate

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

C19H19N3O2S

C19H19N3O2S

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 60℃; for 96h; Autoclave;67%
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Reaxys ID: 26486083

Reaxys ID: 26486083

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide
2: N-Bromosuccinimide / tetrahydrofuran
View Scheme
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid methyl ester

2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
2: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
View Scheme
Multi-step reaction with 2 steps
1: potassium phosphate / water; acetone / 6 h / 40 °C
2: 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / ethyl acetate / Reflux
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 1.5 h / 20 °C
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; N-Bromosuccinimide / tetrahydrofuran / 3 h / 30 - 32 °C
View Scheme
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
2: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
3: sodium hydroxide; water / toluene / 18 - 25 °C
View Scheme
Multi-step reaction with 4 steps
1: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
2: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
3: sodium hydroxide / toluene; water / 18 - 25 °C / Large scale
4: hydrogen bromide / water; ethyl acetate / 30 - 35 °C / pH 2 - 4 / Large scale
View Scheme
Multi-step reaction with 3 steps
1.1: triethylamine / acetone / 0.33 h / 20 °C
1.2: 2 h / 0 - 20 °C
2.1: 1,1'-Thiocarbonyldiimidazole / dichloromethane / 0.25 h / 20 °C
3.1: sodium hydrogencarbonate / acetone / 12 h / 65 °C
View Scheme
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid sodium salt
1151516-14-1

2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid sodium salt

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
2: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
3: sodium hydroxide / toluene; water / 18 - 25 °C / Large scale
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 1.5 h / 20 °C
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; N-Bromosuccinimide / tetrahydrofuran / 3 h / 30 - 32 °C
3: sodium hydroxide; water / tetrahydrofuran / 2 h
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 25 °C
2: sodium hydroxide; N-Bromosuccinimide / N,N-dimethyl-formamide / 3 h / 25 °C
3: sodium hydroxide / ethanol; water / 2 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 1.5 h / 20 °C
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; N-Bromosuccinimide / tetrahydrofuran / 3 h / 30 - 32 °C
3: sodium hydroxide / tetrahydrofuran; water / 2 h
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 50 °C
2: N-Bromosuccinimide / tetrahydrofuran / 2 - 32 °C
3: sodium hydroxide / toluene; water / 10 - 15 °C
View Scheme
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

Reaxys ID: 26486092

Reaxys ID: 26486092

Reaxys ID: 26486087

Reaxys ID: 26486087

Conditions
ConditionsYield
In N,N-dimethyl-formamide
4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol
1533519-84-4

4-(4-cyclopropylnaphthalen-1-yl)-4Η-1,2,4-triazole-3-thiol

phenyl 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate

phenyl 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / isopropyl alcohol / 0.33 h / 20 °C
1.2: 2 h / 0 - 20 °C
2.1: 1,1'-Thiocarbonyldiimidazole / dichloromethane / 0.25 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine / acetone / 0.33 h / 20 °C
1.2: 2 h / 0 - 20 °C
2.1: 1,1'-Thiocarbonyldiimidazole / dichloromethane / 0.25 h / 20 °C
View Scheme

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