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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Nitro-4-methylsulfonyltoluene Manufacturer/High quality/Best price/In stock

Cas:1671-49-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Nitro-4-Methylsulfonyltoluene supplier in China

Cas:1671-49-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-mesyl-2-nitrotoluene

Cas:1671-49-4

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(Methylsulfonyl)-2-nitrotoluene

Cas:1671-49-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Hot saleCAS 1671-49-4 with best quality

Cas:1671-49-4

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name:O-nitro-p-methyl sulfonyl toluene CAS No.:1671-49-4 C8H9O4NS Formula: Technical Specifications: Item : Specification Appearance: white crystall

O-nitro-p-methyl sulfonyl toluene

Cas:1671-49-4

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzene,1-methyl-4-(methylsulfonyl)-2-nitro- 1671-49-4

Cas:1671-49-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 1671-49-4 ,2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Nitro-4-Methylsulfonyltoluene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Benzene,1-methyl-4-(methylsulfonyl)-2-nitro-

Cas:1671-49-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: O-Nitro-P-Methyl Sulfonyl Toluene CAS No.:1671-49-4 Molecule Formula:C8H9NO4S Molecule Weight:215.23 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TE

High Quality O-Nitro-P-Methyl Sulfonyl Toluene on stock

Cas:1671-49-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

2-Nitro-4-methylsulfonyltolueneCAS NO.: 1671-49-4

Cas:1671-49-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Methylsulfonyl-2-nitrotoluene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-Nitro-4-methylsulfonyltoluene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Methylsulfonyl-2-nitrotoluene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

1-Methyl-4-(Methylsulfonyl)-2-nitrobenzene

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

4-Methylsulfonyl-2-nitrotoluene CAS 1671-49-4

Cas:1671-49-4

Min.Order:0

Negotiable

Type:Other

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Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity 2-Nitro-4-Methylsulfonyltoluene 1671-49-4

Cas:1671-49-4

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Hefei TNJ chemical industry co.,ltd

Name: 4-Methylsulfonyl-2-nitrotoluene CAS: 1671-49-4 Molecular Formula: C8H9NO4S Molecular Weight: 215.226 Application:Fine chemical

4-Methylsulfonyl-2-nitrotoluene CAS 1671-49-4

Cas:1671-49-4

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Synthetic route

Methyl p-tolyl sulfone
3185-99-7

Methyl p-tolyl sulfone

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

Conditions
ConditionsYield
With sulfuric acid; nitric acid In water at 100℃; Flow reactor; chemoselective reaction;98%
With sulfuric acid; nitric acid
In sulfuric acid
Methyl p-tolyl sulfone
3185-99-7

Methyl p-tolyl sulfone

A

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

B

Methyl-<3,5-dinitro-4-methyl-phenyl>-sulfon
89977-30-0

Methyl-<3,5-dinitro-4-methyl-phenyl>-sulfon

Conditions
ConditionsYield
With sulfuric acid; nitric acid In water at 75℃; for 0.00416667h; Temperature; Time; Flow reactor; chemoselective reaction;A 90%
B 9%
1-methyl-2-nitrobenzene
88-72-2

1-methyl-2-nitrobenzene

Methanesulfonic anhydride
7143-01-3

Methanesulfonic anhydride

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; tris(trifluoromethanesulfonyloxy)boron at 50℃; for 3h; Substitution;47 % Chromat.
1-methyl-2-nitrobenzene
88-72-2

1-methyl-2-nitrobenzene

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

A

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

B

2-nitro-6-methylsulphonyltoluene
90764-86-6

2-nitro-6-methylsulphonyltoluene

Conditions
ConditionsYield
With aluminum (III) chloride; tetrabutyl-ammonium chloride at 160℃; for 16h; Temperature; Inert atmosphere; Large scale;
1-methyl-2-nitrobenzene
88-72-2

1-methyl-2-nitrobenzene

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: chlorosulfonic acid / 3.5 h / 110 - 115 °C
1.2: 3 h / 60 - 65 °C
2.1: sodium sulfite; sodium carbonate / water / 3 h / 0 - 25 °C / pH 7.5 - 8
2.2: 14 h / 40 - 100 °C
View Scheme
4-methyl-3-nitrobenzenesulfonyl chloride
616-83-1

4-methyl-3-nitrobenzenesulfonyl chloride

chloroacetic acid
79-11-8

chloroacetic acid

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

Conditions
ConditionsYield
Stage #1: 4-methyl-3-nitrobenzenesulfonyl chloride With sodium carbonate; sodium sulfite In water at 0 - 25℃; for 3h; pH=7.5 - 8;
Stage #2: chloroacetic acid With pyrographite In water at 40 - 100℃; for 14h; Temperature;
p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydrogencarbonate; sodium sulfite / water / 9 h / 75 °C
1.2: 4.5 h / 45 - 130 °C
2.1: sulfuric acid / 0.5 h / 20 °C
2.2: 10 h / 10 °C
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

2-methyl-5-(methylsulphonyl)aniline
1671-48-3

2-methyl-5-(methylsulphonyl)aniline

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide In ethyl acetate under 3800.26 Torr; for 1.25h;99%
With platinum(IV) oxide; hydrogen In ethyl acetate under 3800.26 Torr; for 1.25h; Autoclave;99%
With hydrogenchloride; iron
With hydrogenchloride; tin
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

4-methanesulfonyl-2-nitro-benzoic acid
110964-79-9

4-methanesulfonyl-2-nitro-benzoic acid

Conditions
ConditionsYield
With sulfuric acid; oxygen; nitric acid; vanadia at 140℃; for 11h; Temperature;98%
With sulfuric acid; oxygen; nitric acid; vanadia at 138 - 140℃; under 37.5038 Torr; Catalytic behavior; Temperature; Autoclave;96.7%
With oxygen; nitric acid; acetic acid; 2,6-dihydroxypyrrolo[3,4-f]isoindolo-1,3,5,7(2H,6H)tetrone at 150℃; under 37503.8 Torr; for 5h; Catalytic behavior; Reagent/catalyst; Temperature; Pressure; Autoclave;94.9%
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

2-nitro-4-methanesulfonyl-α,α,α-trichlorotoluene

2-nitro-4-methanesulfonyl-α,α,α-trichlorotoluene

Conditions
ConditionsYield
With chlorine; sodium carbonate at 20 - 80℃; under 1500.15 - 6000.6 Torr; for 12h; Temperature; Pressure; Autoclave;93.3%
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

acetic acid
64-19-7

acetic acid

4-methanesulfonyl-2-nitro-benzoic acid
110964-79-9

4-methanesulfonyl-2-nitro-benzoic acid

Conditions
ConditionsYield
With 1,1,2,2-tetrabromoethane; cobalt(II) acetate; manganese(III) triacetate dihydrate In water at 210℃; under 22801.5 Torr; for 3h; Reagent/catalyst; Solvent; Temperature; Pressure; Reflux;92%
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

2-amino-4-(methylsulfonyl)benzoic acid
393085-45-5

2-amino-4-(methylsulfonyl)benzoic acid

Conditions
ConditionsYield
With selenium; cobalt(II) chloride hexahydrate; nitrobenzene In methanol; water; dimethyl sulfoxide at 90℃; for 5h; Inert atmosphere;59%
Multi-step reaction with 2 steps
1: KMnO4; aqueous pyridine
2: iron-powder; aqueous HCl
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

2-iodo-1-methyl-4-(methylsulfonyl)benzene
100959-90-8

2-iodo-1-methyl-4-(methylsulfonyl)benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: iron; aqueous HCl
View Scheme
Multi-step reaction with 2 steps
1.1: platinum(IV) oxide; hydrogen / ethyl acetate / 1.25 h / 3800.26 Torr / Autoclave
2.1: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 °C
2.2: 1 h / 20 °C
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

3-methanesulfonyl-benzo[4,5]thiazolo[2,3-b]quinazolin-12-one

3-methanesulfonyl-benzo[4,5]thiazolo[2,3-b]quinazolin-12-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: KMnO4; aqueous pyridine
2: iron-powder; aqueous HCl
View Scheme
vanadium(V) oxide
788133-24-4

vanadium(V) oxide

1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

4-methanesulfonyl-2-nitro-benzoic acid
110964-79-9

4-methanesulfonyl-2-nitro-benzoic acid

Conditions
ConditionsYield
With nitric acid In sulfuric acid
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

4-methylsulphonyl-2-nitrobenzoyl chloride
110964-80-2

4-methylsulphonyl-2-nitrobenzoyl chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: vanadia; nitric acid / 135 - 160 °C
2: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 6 h / 60 - 65 °C
View Scheme
Multi-step reaction with 2 steps
1.1: vanadia; sulfuric acid; nitric acid / 13 h / 145 - 165 °C
2.1: N,N-dimethyl-formamide / dichloromethane / 0.5 h
2.2: 5 h / 30 - 80 °C
View Scheme
Multi-step reaction with 2 steps
1: oxygen; cobalt(II) chloride; iron(III) sulfate / acetic acid / 300 °C / 18751.9 Torr
2: bis(trichloromethyl) carbonate / N,N-dimethyl-formamide / 3 h / 70 °C
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

3-(4'-methylsulfonyl-2'-nitro-benzoyloxy)-2-cyclohexene-1-one
226944-49-6

3-(4'-methylsulfonyl-2'-nitro-benzoyloxy)-2-cyclohexene-1-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: vanadia; nitric acid / 135 - 160 °C
2: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 6 h / 60 - 65 °C
3: triethylamine / 1,2-dichloro-ethane / 1 h / 5 - 35 °C
View Scheme
Multi-step reaction with 3 steps
1.1: vanadia; sulfuric acid; nitric acid / 13 h / 145 - 165 °C
2.1: N,N-dimethyl-formamide / dichloromethane / 0.5 h
2.2: 5 h / 30 - 80 °C
3.1: tetrabutylammomium bromide / water; dichloromethane / 6 h / 2 °C
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

mesotrione
104206-82-8

mesotrione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: vanadia; nitric acid / 135 - 160 °C
2: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 6 h / 60 - 65 °C
3: triethylamine / 1,2-dichloro-ethane / 1 h / 5 - 35 °C
4: triethylamine; 2-hydroxy-2-methylpropanenitrile / 5 h / 20 - 25 °C
View Scheme
Multi-step reaction with 4 steps
1.1: vanadia; sulfuric acid; nitric acid / 13 h / 145 - 165 °C
2.1: N,N-dimethyl-formamide / dichloromethane / 0.5 h
2.2: 5 h / 30 - 80 °C
3.1: tetrabutylammomium bromide / water; dichloromethane / 6 h / 2 °C
4.1: triethylamine / dichloromethane / 0.25 h / 30 °C
4.2: 3 h / 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: oxygen; cobalt(II) chloride; iron(III) sulfate / acetic acid / 300 °C / 18751.9 Torr
2.1: bis(trichloromethyl) carbonate / N,N-dimethyl-formamide / 3 h / 70 °C
3.1: 15-crown-5; sodium hydroxide / chloroform / 1.5 h / 35 °C
3.2: 3.5 h / 350 °C
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

A

(R)-6-(methylsulfonyl)-3-(2-phenylbut-3-en-2-yl)-1H-indazole

(R)-6-(methylsulfonyl)-3-(2-phenylbut-3-en-2-yl)-1H-indazole

B

6-(methylsulfonyl)-3-(2-phenylbut-3-en-2-yl)-1H-indazole

6-(methylsulfonyl)-3-(2-phenylbut-3-en-2-yl)-1H-indazole

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Inert atmosphere; Reflux
2: ammonia / methanol / 20 °C
3: sodium hydroxide / methanol / Reflux
4: dmap / diethyl ether / 20 °C / Inert atmosphere
5: copper diacetate; (+)-1,2-bis((2S,5S)-2,5-diphenylphospholanyl)ethane; (dimethoxy)methylsilane / tetrahydrofuran / 12 h / 60 °C / Inert atmosphere; Glovebox; Sealed tube
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

6-(methylsulfonyl)-1H-indazol-1-yl 2,4,6-trimethylbenzoate

6-(methylsulfonyl)-1H-indazol-1-yl 2,4,6-trimethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Inert atmosphere; Reflux
2: ammonia / methanol / 20 °C
3: sodium hydroxide / methanol / Reflux
4: dmap / diethyl ether / 20 °C / Inert atmosphere
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

6-(methylsulfonyl)-1H-indazol-1-ol

6-(methylsulfonyl)-1H-indazol-1-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Inert atmosphere; Reflux
2: ammonia / methanol / 20 °C
3: sodium hydroxide / methanol / Reflux
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

4-(methylsulfonyl)-2-nitrobenzylamine

4-(methylsulfonyl)-2-nitrobenzylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Inert atmosphere; Reflux
2: ammonia / methanol / 20 °C
View Scheme
1-methyl-4-(methylsulfonyl)-2-nitrobenzene
1671-49-4

1-methyl-4-(methylsulfonyl)-2-nitrobenzene

2-nitro-4-(methylsulphonyl)benzyl bromide

2-nitro-4-(methylsulphonyl)benzyl bromide

Conditions
ConditionsYield
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane Inert atmosphere; Reflux;

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