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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)-

Cas:175277-74-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Pyridinemethanamine, 3-Chloro-5-(Trifluoromethyl)-

Cas:175277-74-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 175277-74-4 with best price

Cas:175277-74-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE CAS:175277-74-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical interme

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE CAS:175277-74-4

Cas:175277-74-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)-

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)-

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methanamine hydrochloride CAS NO.175277-74-4

Cas:175277-74-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

BUTTPARK 145\04-45; 2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE;[3-Chloro-5-(trifluoromethyl)-2-pyridyl]methylamine hydrochloride;2-(Aminomethyl)- 3-chloro-5-(trifluoromethyl)pyridine hydrochloride 97%; 2-(Aminomethyl)-3-chl

2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)pyridine hydrochloride 97%

Cas:175277-74-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-(Aminomethyl)-3-Chloro-5-(Trifluoromethyl)-PyridineHydrochloride

Cas:175277-74-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)-

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine cas no. 175277-74-4 98%

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2-Aminomethyl-3-Chloro-5- (Trifluoromethyl)Pyridine

Cas:175277-74-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)pyridine hydrochloride 97%

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINEHYDROCHLORIDE CAS No.175277-74-4

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:White Powder Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by Sea, by Air, by

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)- cas 175277-74-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-Pyridinemethanamine,3-chloro-5-(trifluoromethyl)- cas 175277-74-4

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine

Cas:175277-74-4

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

3-chloro-2-nitromethyl-5-(trifluoromethyl)pyridine

3-chloro-2-nitromethyl-5-(trifluoromethyl)pyridine

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

Conditions
ConditionsYield
With Ni-doped silica; hydrogen at 30℃; under 15001.5 Torr; Concentration; Pressure; Reagent/catalyst;98.57%
With hydrogenchloride; tin(ll) chloride In ethanol Reflux;
3-chloro-2-cyano-5-(trifluoromethyl)pyridine
80194-70-3

3-chloro-2-cyano-5-(trifluoromethyl)pyridine

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

Conditions
ConditionsYield
Stage #1: 3-chloro-2-cyano-5-(trifluoromethyl)pyridine With sodium hydroxide In methanol at 70℃;
Stage #2: With sodium hypochlorite In methanol at 10℃; Solvent; Reagent/catalyst; Temperature;
98%
With sulfuric acid; 20% palladium hydroxide-activated charcoal; tetrabutylammomium bromide; hydrogen In methanol at 20℃; under 15001.5 Torr;96.4%
3-chloro-2-cyano-5-(trifluoromethyl)pyridine
80194-70-3

3-chloro-2-cyano-5-(trifluoromethyl)pyridine

A

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

B

1-[5-(trifluoromethyl)pyridin-2-yl]methanamine
164341-39-3

1-[5-(trifluoromethyl)pyridin-2-yl]methanamine

Conditions
ConditionsYield
With hydrogen; acetic acid; nickel at 40 - 45℃; under 13501.4 Torr; for 4h;A 97%
B 0.05%
C10H10ClF3N2O2*ClH

C10H10ClF3N2O2*ClH

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

Conditions
ConditionsYield
Stage #1: C10H10ClF3N2O2*ClH With hydrogenchloride In water at 90 - 100℃; for 8h;
Stage #2: With sodium hydroxide In water pH=9 - 9.2; Concentration; Temperature;
90.9%
methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(diphenylmethyleneamino)-acetate

methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(diphenylmethyleneamino)-acetate

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride; water / toluene / 20 °C / Inert atmosphere
2: hydrogenchloride / water / 5 h / Reflux; Inert atmosphere
View Scheme
methyl 2-amino-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate hydrochloride

methyl 2-amino-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate hydrochloride

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

Conditions
ConditionsYield
With hydrogenchloride In water for 5h; Reflux; Inert atmosphere;
2,3-dichloro-5-trifluoromethylpyridine
69045-84-7

2,3-dichloro-5-trifluoromethylpyridine

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetrabutylammomium bromide; potassium carbonate / toluene; propiononitrile / 22 h / Inert atmosphere; Reflux
2: hydrogenchloride; water / toluene / 20 °C / Inert atmosphere
3: hydrogenchloride / water / 5 h / Reflux; Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: potassium hydroxide / dimethyl sulfoxide / 20 °C
2: tin(ll) chloride; hydrogenchloride / ethanol / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: potassium carbonate; tetraethylammonium bromide / toluene / 18 h / 90 °C / Inert atmosphere
2.1: sodium tetraborate; hydrogenchloride / water / 12 h / 25 °C / Inert atmosphere
3.1: hydrogenchloride / water / 8 h / 90 - 100 °C
3.2: pH 9 - 9.2
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

formic acid
64-18-6

formic acid

C8H6ClF3N2O

C8H6ClF3N2O

Conditions
ConditionsYield
With acetic anhydride at 20℃; for 16h; Concentration;91%
With acetic anhydride at 20℃; for 16h;
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

3,4,6-tribromopyridazine
55928-86-4

3,4,6-tribromopyridazine

C11H6Br2ClF3N4

C11H6Br2ClF3N4

Conditions
ConditionsYield
With triethylamine In methanol at 20℃;85%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

3,4,6-trichloropyridazine
6082-66-2

3,4,6-trichloropyridazine

C11H6Cl3F3N4

C11H6Cl3F3N4

Conditions
ConditionsYield
With triethylamine In methanol at 20℃;82.2%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

thiophosgene
463-71-8

thiophosgene

8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridine-3-thiol
1326718-41-5

8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridine-3-thiol

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane; water at 0 - 20℃; Inert atmosphere;80%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzoic acid

2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzoic acid

N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzamide

N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzamide

Conditions
ConditionsYield
Stage #1: 2-methyl-4-(5-(trifluoromethyl)-5-(3,4,5-trifluorophenyl)-4,5-dihydroisoxazol-3-yl)benzoic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 2h;
Stage #2: (3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine In dichloromethane at 20℃; for 15h;
76%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-ol
1326718-42-6

8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-ol

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane; water at 0 - 20℃; Inert atmosphere;72%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methylbenzoic acid
1332698-41-5

4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methylbenzoic acid

N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzamide

N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzamide

Conditions
ConditionsYield
Stage #1: 4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methylbenzoic acid With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 2h;
Stage #2: (3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine In dichloromethane at 20℃; for 15h;
72%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

p-(chloromethyl)benzoyl chloride
876-08-4

p-(chloromethyl)benzoyl chloride

N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-4-(chloromethyl)benzamide

N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-4-(chloromethyl)benzamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃;68%
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

4-(4'-trifluoromethyl-biphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid
486436-98-0

4-(4'-trifluoromethyl-biphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid

N-ethyl-N,N-diisopropylamine
7087-68-5

N-ethyl-N,N-diisopropylamine

N-(3-chloro-5-trifluoromethylpyridin-2-yl-methyl)-4-(4'-trifluoromethylbiphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid amide
486435-50-1

N-(3-chloro-5-trifluoromethylpyridin-2-yl-methyl)-4-(4'-trifluoromethylbiphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid amide

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate In N-methyl-acetamide
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

4-(4'-trifluoromethyl-biphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid
486436-98-0

4-(4'-trifluoromethyl-biphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid

N-(3-chloro-5-trifluoromethylpyridin-2-yl-methyl)-4-(4'-trifluoromethylbiphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid amide
486435-50-1

N-(3-chloro-5-trifluoromethylpyridin-2-yl-methyl)-4-(4'-trifluoromethylbiphenyl-2-carbonylamino)-1-methyl-pyrrole-2-carboxylic acid amide

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N-methyl-acetamide
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

2-amino-4-methanesulfinyl-6-(4-methyl-furan-2-yl)-pyrimidine-5-carbonitrile
357288-45-0

2-amino-4-methanesulfinyl-6-(4-methyl-furan-2-yl)-pyrimidine-5-carbonitrile

2-Amino-4-[(3-chloro-5-trifluoromethyl-pyridin-2-yl-methyl)-amino]-6-(4-methyl-furan-2-yl)-pyrimidine-5-carbonitrile
357284-48-1

2-Amino-4-[(3-chloro-5-trifluoromethyl-pyridin-2-yl-methyl)-amino]-6-(4-methyl-furan-2-yl)-pyrimidine-5-carbonitrile

Conditions
ConditionsYield
In 1,2-dimethoxyethane
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

2-trifluoromethylbenzoyl chloride
312-94-7

2-trifluoromethylbenzoyl chloride

N-[(3-Chloro-5-trifluoromethyl-pyridin-2-yl)methyl]-α,α,α-trifluoro-o-toluamide
239109-95-6

N-[(3-Chloro-5-trifluoromethyl-pyridin-2-yl)methyl]-α,α,α-trifluoro-o-toluamide

Conditions
ConditionsYield
With triethylamine In water; ethyl acetate
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

2-furancarbonyl chloride
527-69-5

2-furancarbonyl chloride

A

petroleum

petroleum

B

N-[(3-Chloro-5-trifluoromethyl-pyridin-2-yl)methyl]-2-furamide
326475-66-5

N-[(3-Chloro-5-trifluoromethyl-pyridin-2-yl)methyl]-2-furamide

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

ethyl 2-(2-amino-4,6-dichloropyrimidin-5-yl)acetate
848694-76-8

ethyl 2-(2-amino-4,6-dichloropyrimidin-5-yl)acetate

ethyl 2-(2-amino-4-chloro-6-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methylamino)pyrimidin-5-yl)acetate
1196887-83-8

ethyl 2-(2-amino-4-chloro-6-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methylamino)pyrimidin-5-yl)acetate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 80 - 90℃;
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl acetate
1477503-51-7

3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trichlorophosphate / benzene / 6 h / 20 °C / Reflux
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl cyclohexane carboxylate
1477503-66-4

3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl cyclohexane carboxylate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trichlorophosphate / benzene / 6 h / 20 °C / Reflux
3: sodium hydroxide / tetrahydrofuran; water / 3 h / 20 °C
4: triethylamine
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

1-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenoxy)propan-2-one
1477503-67-5

1-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenoxy)propan-2-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trichlorophosphate / benzene / 6 h / 20 °C / Reflux
3: sodium hydroxide / tetrahydrofuran; water / 3 h / 20 °C
4: potassium carbonate
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

N-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)acetamide
1477503-71-1

N-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)acetamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trifluoroacetic acid / dichloromethane / 20 °C
3: dmap / dichloromethane / 20 °C
4: pyridine; trichlorophosphate / 1,2-dichloro-ethane / 7 h / 20 °C / Reflux
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

N-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)cyclohexane carboxamide
1477503-72-2

N-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)cyclohexane carboxamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trifluoroacetic acid / dichloromethane / 20 °C
3: triethylamine; dmap / dichloromethane / 20 °C
4: pyridine; trichlorophosphate / 1,2-dichloro-ethane / 7 h / 20 °C / Reflux
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

1-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)pyrrolidine-2,5-dione
1477503-73-3

1-(3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)pyrrolidine-2,5-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trifluoroacetic acid / dichloromethane / 20 °C
3: potassium carbonate / acetonitrile / Reflux
4: pyridine; trichlorophosphate / 1,2-dichloro-ethane / 7 h / 20 °C / Reflux
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

tert-butyl (3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)carbamate
1477503-74-4

tert-butyl (3-(8-chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl)phenyl)carbamate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: pyridine; trichlorophosphate / 1,2-dichloro-ethane / 7 h / 20 °C / Reflux
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

C14H8ClF3N2O
1477503-52-8

C14H8ClF3N2O

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trichlorophosphate / benzene / 6 h / 20 °C / Reflux
3: sodium hydroxide / tetrahydrofuran; water / 3 h / 20 °C
View Scheme
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine
175277-74-4

(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

C16H13ClF3N3O2
1477503-68-6

C16H13ClF3N3O2

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: trifluoroacetic acid / dichloromethane / 20 °C
3: dmap / dichloromethane / 20 °C
View Scheme

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