Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

6-BROMO-2,3-DIHYDROBENZOFURAN

Cas:189035-22-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzofuran,6-bromo-2,3-dihydro-

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 6-BROMO-2,3-DIHYDRO-BENZOFURAN Synonyms: 6-broMo-2,3-dihydro-1-benzofuran;6-BROMO-2,3-DIHYDRO-BENZOFURAN;6-Bromo-2,3-dihydrobenzo[b]furan;Benzofuran, 6-bromo-2,3-dihydro- CAS: 189035-22-1 MF: C8H7BrO MW: 199.04 EINECS:

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

6-Bromo-2,3-dihydrobenzofuran

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

6-BROMO-2,3-DIHYDROBENZOFURANAppearance:detailed in specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:An important raw material and intermediate used in Organic Synthesis, Pharmaceuticals Transportation:Se

6-BROMO-2,3-DIHYDROBENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

The factory supplies Application:manufacturing supplies

Benzofuran,6-bromo-2,3-dihydro-

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

home-produced Application:medicine

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

6-Bromo-2,3-dihydrobenzofuran

Cas:189035-22-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

6-BROMO-2,3-DIHYDROBENZOFURAN CAS NO.189035-22-1

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Reply quotation within 2 hours.Guarantee the time of delivery. Update the progress of customization Weekly.High purity& High product customization success rate.Inquiries for other compounds are acceptable. Storage:refrigeration Package:1g,5g,10g,100g

6-bromo-2,3-dihydrobenzofuran

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Nanjing Chemlin Chemical Industry Co., Ltd was established in Aug,1999, located in the industrial park of Nanjing University of Technology, It is a private enterprises in Jiangsu Province with 1200 square meters’ R&D center. Our R&D center has a well

189035-22-1

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai PotentPharm Science and Technology Co.,Ltd

1 good quality, better price and bettter service;2 Timely delivery;3 100% refunded if parcel is t delivered or poor quality.We will try to satisfy you upon receipt of your reply. I hope that we can become a long-term cooperative partner. Application:

Benzofuran,6-bromo-2,3-dihydro-

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zhengzhou Aixi Pharmtech Co.,Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:send with COA Storage:keep sealed and keep from direct light Package:According client's requirements Application:Pharmaceutic

6-BROMO-2,3-DIHYDRO-BENZOFURAN manufacture

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI ZZBIO CO., LTD.

Comprehensive range product, High quality, Quick shippment, COA with spectras Package:0.25g Application:pharmaceutical industry, food industry, research

6-Bromo-2,3-dihydrobenzofuran

Cas:189035-22-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1,4-dibromo-2-(2-bromoethoxy)benzene
377091-18-4

1,4-dibromo-2-(2-bromoethoxy)benzene

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 4h;94%
With n-butyllithium In tetrahydrofuran; benzene at -78℃; for 1h; Inert atmosphere;85%
With n-butyllithium In tetrahydrofuran; benzene at -78℃; for 1h; Inert atmosphere;85%
1,4-dibromo-2-hydroxyethoxybenzene
377091-17-3

1,4-dibromo-2-hydroxyethoxybenzene

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
Stage #1: 1,4-dibromo-2-hydroxyethoxybenzene With phosphorus tribromide In toluene at 90℃; for 2.5h; Heating / reflux;
Stage #2: With sodium hydroxide In water; toluene at 20℃;
Stage #3: With n-butyllithium In tetrahydrofuran; hexane at -75℃; for 0.5h;
40%
Multi-step reaction with 2 steps
1: phosphorus tribromide / toluene / 10 h / 90 °C
2: n-butyllithium / tetrahydrofuran; benzene / 1 h / -78 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: phosphorus tribromide / toluene / 2.5 h / 20 - 90 °C
2: n-butyllithium / tetrahydrofuran; hexane / 2.5 h / -78 - 0 °C / Inert atmosphere
View Scheme
2,3-Dihydrobenzofuran
496-16-2

2,3-Dihydrobenzofuran

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
With potassium hydroxide; bromine; potassium bromide at 20℃;
2-trimethylstannyl-1,3-cyclohexadiene

2-trimethylstannyl-1,3-cyclohexadiene

Br2 -solution

Br2 -solution

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
In n-heptane; dichloromethane; ethyl acetate
2,5-dibromophenol
28165-52-8

2,5-dibromophenol

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / 40 h / 80 °C
2: n-butyllithium / hexane; tetrahydrofuran / 4 h / -78 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 4 h / 80 °C
2: n-butyllithium / tetrahydrofuran / 3 h / -100 °C
View Scheme
2,5-dibromofluorobenzene
1435-52-5

2,5-dibromofluorobenzene

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1-methyl-pyrrolidin-2-one; potassium tert-butylate / 100 °C / Inert atmosphere
2: phosphorus tribromide / toluene / 10 h / 90 °C
3: n-butyllithium / tetrahydrofuran; benzene / 1 h / -78 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 100 °C / Inert atmosphere
2: phosphorus tribromide / toluene / 10 h / 90 °C
3: n-butyllithium / tetrahydrofuran; benzene / 1 h / -78 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: potassium tert-butylate; 1-methyl-pyrrolidin-2-one / 15 h / 20 - 100 °C
2: phosphorus tribromide / toluene / 2.5 h / 20 - 90 °C
3: n-butyllithium / tetrahydrofuran; hexane / 2.5 h / -78 - 0 °C / Inert atmosphere
View Scheme
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

5,6-dibromo-2,3-dihydro-1-benzofuran
1102467-17-3

5,6-dibromo-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
With N-Bromosuccinimide In acetonitrile at 20℃; for 3h;93%
With N-Bromosuccinimide In acetonitrile at 20℃;
potassium cyanide

potassium cyanide

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

C9H7NO

C9H7NO

Conditions
ConditionsYield
Stage #1: potassium cyanide With acetic acid In ethylene glycol at 20℃; Sealed tube;
Stage #2: 6-bromo-2,3-dihydro-1-benzofuran With P(t-Bu)3 Palladacycle Gen. 3; potassium acetate In 1,4-dioxane; water at 60℃; for 16h; Sealed tube;
93%
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-oxocyclopenta-1,3-dieno[2,1-b]pyridine
496047-46-2

7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-oxocyclopenta-1,3-dieno[2,1-b]pyridine

7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-5-hydroxy-5H-cyclopenta[b]pyridine
721965-55-5

7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-5-hydroxy-5H-cyclopenta[b]pyridine

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran
Stage #2: 7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-oxocyclopenta-1,3-dieno[2,1-b]pyridine In tetrahydrofuran at -78℃; for 1h; Grignard reaction;
89%
N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

2,3-dihydro-1-benzofuran-6-carbaldehyde
55745-96-5

2,3-dihydro-1-benzofuran-6-carbaldehyde

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In 2-methyltetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In 2-methyltetrahydrofuran; hexane at -78℃; for 2h;
85%
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran; hexane at -75℃; for 0.5h;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; hexane at 20℃; for 0.75h;
79%
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
52%
2-ethylhexyl 3-sulfanylpropanoate
50448-95-8

2-ethylhexyl 3-sulfanylpropanoate

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

2-ethylhexyl 3-(2,3-dihydro-1-benzofuran-6-ylthio)propanoate
1156468-65-3

2-ethylhexyl 3-(2,3-dihydro-1-benzofuran-6-ylthio)propanoate

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 10h; Inert atmosphere;83%
With N-ethyl-N,N-diisopropylamine; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane at 100℃; for 10h;33%
pinacol vinylboronate
75927-49-0

pinacol vinylboronate

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

6-vinyl-2,3-dihydrobenzofuran

6-vinyl-2,3-dihydrobenzofuran

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In 1,4-dioxane; water at 105℃; for 16h;79.4%
formaldehyd
50-00-0

formaldehyd

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(2,3-dihydrobenzofuran-6-yl)methanol
1083168-69-7

(2,3-dihydrobenzofuran-6-yl)methanol

Conditions
ConditionsYield
With tert.-butyl lithium In tetrahydrofuran; pentane at -74 - 20℃; Inert atmosphere;74%
tributyl(1-ethoxyvinyl)stannane
97674-02-7

tributyl(1-ethoxyvinyl)stannane

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

1-(2,3-dihydrobenzofuran-6-yl)ethan-1-one
374706-07-7

1-(2,3-dihydrobenzofuran-6-yl)ethan-1-one

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In toluene at 90℃; for 16h;73.7%
oxirene
157-18-6

oxirene

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

2-(2,3-dihydrobenzofuran-6-yl)ethan-1-ol

2-(2,3-dihydrobenzofuran-6-yl)ethan-1-ol

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With iodine; magnesium In tetrahydrofuran at 20 - 70℃; for 1h; Inert atmosphere;
Stage #2: oxirene In tetrahydrofuran at 20℃; for 2h;
64.3%
Dimethyldisulphide
624-92-0

Dimethyldisulphide

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

6-(methylthio)-2,3-dihydro-1-benzofuran
1102467-20-8

6-(methylthio)-2,3-dihydro-1-benzofuran

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran; hexanes at -78℃; for 0.5h;
Stage #2: Dimethyldisulphide In tetrahydrofuran; hexanes for 1h;
62%
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

2-(N-benzylisopropylamino)-6-chloro-5-{(E)-[2-(4S,5S)-4-methoxymethyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazol-2-yl]vinyl}pyridine
464170-04-5

2-(N-benzylisopropylamino)-6-chloro-5-{(E)-[2-(4S,5S)-4-methoxymethyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazol-2-yl]vinyl}pyridine

(3S)-3-[6-(N-benzyl-N-isopropylamino)-2-chloro-3-pyridinyl]-3-(2,3-dihydro-1-benzofuran-6-yl)propanoic acid
464170-05-6

(3S)-3-[6-(N-benzyl-N-isopropylamino)-2-chloro-3-pyridinyl]-3-(2,3-dihydro-1-benzofuran-6-yl)propanoic acid

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: 2-(N-benzylisopropylamino)-6-chloro-5-{(E)-[2-(4S,5S)-4-methoxymethyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazol-2-yl]vinyl}pyridine In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #3: With sulfuric acid In 1,4-dioxane; water at 100℃; for 1.5h;
60%
2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine
765287-34-1

2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(2,3-dihydro-benzofuran-6-yl)-[2-(6-trifluoromethyl-pyridin-3-yl)-ethyl]-amine
1201195-88-1

(2,3-dihydro-benzofuran-6-yl)-[2-(6-trifluoromethyl-pyridin-3-yl)-ethyl]-amine

Conditions
ConditionsYield
With caesium carbonate; copper(l) iodide; 2-acetylcyclohexanone In N,N-dimethyl-formamide at 120℃; for 2h; Inert atmosphere;52%
tert-butyl 2-oxopyrrolidine-1-carboxylate
85909-08-6

tert-butyl 2-oxopyrrolidine-1-carboxylate

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

tert-butyl (4-(2,3-dihydrobenzofuran-6-yl)-4-oxobutyl)carbamate

tert-butyl (4-(2,3-dihydrobenzofuran-6-yl)-4-oxobutyl)carbamate

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium; lithium chloride In tetrahydrofuran; ethylene dibromide at 65℃; for 2h;
Stage #2: tert-butyl 2-oxopyrrolidine-1-carboxylate In tetrahydrofuran; ethylene dibromide at -78℃; for 2h;
37%
3-(((4-methoxybenzyl)(methyl)amino)methyl)-2-methylbenzofuran-7-ol

3-(((4-methoxybenzyl)(methyl)amino)methyl)-2-methylbenzofuran-7-ol

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

1-(7-((2,3-dihydrobenzofuran-6-yl)oxy)-2-methylbenzofuran-3-yl)-N-(4-methoxybenzyl)-N-methylmethanamine

1-(7-((2,3-dihydrobenzofuran-6-yl)oxy)-2-methylbenzofuran-3-yl)-N-(4-methoxybenzyl)-N-methylmethanamine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; dimethylaminoacetic acid In dimethyl sulfoxide at 110℃; for 16h;27%
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

Benzyl-(6-bromo-5-{(E)-2-[(4S,5S)-4-methoxymethyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-2-yl]-vinyl}-pyridin-2-yl)-isopropyl-amine

Benzyl-(6-bromo-5-{(E)-2-[(4S,5S)-4-methoxymethyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-2-yl]-vinyl}-pyridin-2-yl)-isopropyl-amine

(S)-3-[6-(Benzyl-isopropyl-amino)-2-bromo-pyridin-3-yl]-3-(2,3-dihydro-benzofuran-6-yl)-propionic acid

(S)-3-[6-(Benzyl-isopropyl-amino)-2-bromo-pyridin-3-yl]-3-(2,3-dihydro-benzofuran-6-yl)-propionic acid

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: Benzyl-(6-bromo-5-{(E)-2-[(4S,5S)-4-methoxymethyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-2-yl]-vinyl}-pyridin-2-yl)-isopropyl-amine In tetrahydrofuran; hexane at -78℃;
Stage #3: With sulfuric acid In 1,4-dioxane; water at 100℃;
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-isopropyl-oxazolidin-2-one
494841-72-4

(S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-isopropyl-oxazolidin-2-one

(S)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4-isopropyl-oxazolidin-2-one

(S)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4-isopropyl-oxazolidin-2-one

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran at 70℃; for 2h;
Stage #2: With copper(I) bromide dimethylsulfide complex In tetrahydrofuran at 5℃; for 0.333333h;
Stage #3: (S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-isopropyl-oxazolidin-2-one In tetrahydrofuran at -78℃; for 1h; Michael addition;
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-phenyl-oxazolidin-2-one
494841-70-2

(S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-phenyl-oxazolidin-2-one

(S)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4-phenyl-oxazolidin-2-one

(S)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4-phenyl-oxazolidin-2-one

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran at 70℃; for 2h;
Stage #2: With copper(I) bromide dimethylsulfide complex In tetrahydrofuran at 5℃; for 0.333333h;
Stage #3: (S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-phenyl-oxazolidin-2-one In tetrahydrofuran at -78℃; for 1h; Michael addition;
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(4S,5R)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-methyl-5-phenyl-oxazolidin-2-one
494841-71-3

(4S,5R)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-methyl-5-phenyl-oxazolidin-2-one

(4S,5R)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4-methyl-5-phenyl-oxazolidin-2-one

(4S,5R)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4-methyl-5-phenyl-oxazolidin-2-one

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran at 70℃; for 2h;
Stage #2: With copper(I) bromide dimethylsulfide complex In tetrahydrofuran at 5℃; for 0.333333h;
Stage #3: (4S,5R)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4-methyl-5-phenyl-oxazolidin-2-one In tetrahydrofuran at -78℃; for 1h; Michael addition;
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(R)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-5,5-dimethyl-4-phenyl-oxazolidin-2-one
494841-73-5

(R)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-5,5-dimethyl-4-phenyl-oxazolidin-2-one

(R)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-5,5-dimethyl-4-phenyl-oxazolidin-2-one

(R)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-5,5-dimethyl-4-phenyl-oxazolidin-2-one

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran at 70℃; for 2h;
Stage #2: With copper(I) bromide dimethylsulfide complex In tetrahydrofuran at 5℃; for 0.333333h;
Stage #3: (R)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-5,5-dimethyl-4-phenyl-oxazolidin-2-one In tetrahydrofuran at -78℃; for 1h; Michael addition;
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

2-chloro-3-{(E)-[2-(4S,5S)-4-methoxymethyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazol-2-yl]vinyl}pyridine
494841-80-4

2-chloro-3-{(E)-[2-(4S,5S)-4-methoxymethyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazol-2-yl]vinyl}pyridine

2-Chloro-3-{1-(2,3-dihydro-benzofuran-6-yl)-2-[(4S,5S)-4-methoxymethyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-2-yl]-ethyl}-pyridine

2-Chloro-3-{1-(2,3-dihydro-benzofuran-6-yl)-2-[(4S,5S)-4-methoxymethyl-5-(4-methylsulfanyl-phenyl)-4,5-dihydro-oxazol-2-yl]-ethyl}-pyridine

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: 2-chloro-3-{(E)-[2-(4S,5S)-4-methoxymethyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazol-2-yl]vinyl}pyridine In tetrahydrofuran; hexane at -78℃;
76 % Chromat.
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(4R,5S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4,5-diphenyl-oxazolidin-2-one
494841-74-6

(4R,5S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4,5-diphenyl-oxazolidin-2-one

(4R,5S)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4,5-diphenyl-oxazolidin-2-one

(4R,5S)-3-[3-(2-Chloro-pyridin-3-yl)-3-(2,3-dihydro-benzofuran-6-yl)-propionyl]-4,5-diphenyl-oxazolidin-2-one

Conditions
ConditionsYield
Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran at 70℃; for 2h;
Stage #2: With copper(I) bromide dimethylsulfide complex In tetrahydrofuran at 5℃; for 0.333333h;
Stage #3: (4R,5S)-3-[(E)-3-(2-Chloro-pyridin-3-yl)-acryloyl]-4,5-diphenyl-oxazolidin-2-one In tetrahydrofuran at -78℃; for 1h; Michael addition;
ethyl acrylate
140-88-5

ethyl acrylate

6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(E)-3-(2,3-Dihydro-benzofuran-6-yl)-acrylic acid ethyl ester

(E)-3-(2,3-Dihydro-benzofuran-6-yl)-acrylic acid ethyl ester

Conditions
ConditionsYield
With palladium diacetate; triethylamine; tris-(o-tolyl)phosphine In acetonitrile at 90℃;
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

5-(2,3-dihydro-benzofuran-6-yl)-7-(2-hydroxy-4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester

5-(2,3-dihydro-benzofuran-6-yl)-7-(2-hydroxy-4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Mg / tetrahydrofuran
1.2: 89 percent / tetrahydrofuran / 1 h / -78 °C
2.1: 4-(dimethylamino)pyridine / CHCl3 / 1 h / 20 °C
3.1: 189 g / H2; NaHCO3 / Pd(OH)2/C / tetrahydrofuran; ethanol / 45 h / 20 °C / 760 Torr
4.1: potassium tert-butoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 0.33 h / 0 °C
View Scheme
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(5RS,6RS,7SR)-7-(2-hydroxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine

(5RS,6RS,7SR)-7-(2-hydroxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: Mg / tetrahydrofuran
1.2: 89 percent / tetrahydrofuran / 1 h / -78 °C
2.1: 4-(dimethylamino)pyridine / CHCl3 / 1 h / 20 °C
3.1: 189 g / H2; NaHCO3 / Pd(OH)2/C / tetrahydrofuran; ethanol / 45 h / 20 °C / 760 Torr
View Scheme
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

5-(2,3-dihydro-benzofuran-6-yl)-7-(4-methoxy-2-vinyl-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester

5-(2,3-dihydro-benzofuran-6-yl)-7-(4-methoxy-2-vinyl-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: Mg / tetrahydrofuran
1.2: 89 percent / tetrahydrofuran / 1 h / -78 °C
2.1: 4-(dimethylamino)pyridine / CHCl3 / 1 h / 20 °C
3.1: 189 g / H2; NaHCO3 / Pd(OH)2/C / tetrahydrofuran; ethanol / 45 h / 20 °C / 760 Torr
4.1: potassium tert-butoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 0.33 h / 0 °C
5.1: 172 g / 4-(dimethylamino)pyridine / CHCl3 / 0.5 h / 0 °C
6.1: dichloro[bis(triphenylphosphine)]palladium; LiCl / dimethylformamide / 4 h / 125 °C
6.2: 112 g / KF / dimethylformamide; H2O; ethyl acetate / 0.5 h / 20 °C
View Scheme
6-bromo-2,3-dihydro-1-benzofuran
189035-22-1

6-bromo-2,3-dihydro-1-benzofuran

(5RS,6SR,7SR)-7-(2-hydroxymethyl-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine

(5RS,6SR,7SR)-7-(2-hydroxymethyl-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: Mg / tetrahydrofuran
1.2: 89 percent / tetrahydrofuran / 1 h / -78 °C
2.1: 4-(dimethylamino)pyridine / CHCl3 / 1 h / 20 °C
3.1: 189 g / H2; NaHCO3 / Pd(OH)2/C / tetrahydrofuran; ethanol / 45 h / 20 °C / 760 Torr
4.1: potassium tert-butoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 0.33 h / 0 °C
5.1: 172 g / 4-(dimethylamino)pyridine / CHCl3 / 0.5 h / 0 °C
6.1: dichloro[bis(triphenylphosphine)]palladium; LiCl / dimethylformamide / 4 h / 125 °C
6.2: 112 g / KF / dimethylformamide; H2O; ethyl acetate / 0.5 h / 20 °C
7.1: OsO4; 4-methylmorpholine N-oxide / tetrahydrofuran; H2O / 12 h / 20 °C
8.1: NaIO4; 4-methylmorpholine N-oxide / tetrahydrofuran; H2O / 0.33 h / 0 °C
8.2: 84.2 g / NaBH4 / tetrahydrofuran; H2O / 0.33 h / 20 °C
View Scheme

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View