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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Hydroxyindole Manufacturer/High quality/Best price/In stock

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Hydroxyindole supplier in China

Cas:1953-54-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Indolol

Cas:1953-54-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFUCHEM- 5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

5-Hydroxyindole CAS 1953-54-4

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 1953-54-4 with best quality

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

5-Indolol/5-Hydroxyindole 1953-54-4

Cas:1953-54-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powder 2. Fact

5-HydroxyindoleCAS1953-54-4

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $8.0 / 9.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 5-Hydroxyindole Synonyms: 5-Hydroxy-1H-indole;Hydroxy-5 indole;hydroxy-5indole;TIMTEC-BB SBB004214;1H-INDOL-5-OL;5-HYDROXYINDOLE;5-INDOLOL;INDOL-5-OL CAS: 1953-54-4

5-Hydroxyindole CAS: 1953-54-4

Cas:1953-54-4

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Hydroxyindole 1953-54-4

Cas:1953-54-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Organic Synthesis, 5-Hydroxyindole CAS:1953-54-4

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $72.0 / 81.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Hydroxyindole CAS:1953-54-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

5-Hydroxyindole CAS:1953-54-4

Cas:1953-54-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Indolol

Cas:1953-54-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

5-Hydroxyindole

Cas:1953-54-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

5-Hydroxyindole CAS NO.1953-54-4

Cas:1953-54-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Hydroxyindole

Cas:1953-54-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Hydroxyindole

Cas:1953-54-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1H-Indol-5-ol

Cas:1953-54-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Hydroxyindole

Cas:1953-54-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5-Hydroxyindole CAS NO.1953-54-4

Cas:1953-54-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

5-Hydroxyindole

Cas:1953-54-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 5-Hydroxyindole CAS No.: 1953-54-4 Molecule Formula:C8H7NO Molecule Weight:133.15 Purity: 98.0% Package: 25kg/drum Description:Off-white to grey crystalline powder Manufacture Standards:Enterprise Standard

Lower Price 5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

5-Hydroxyindole Basic information Product Name: 5-Hydroxyindole Synonyms: 5-Hydroxy-1H-indole;Hydroxy-5 indole;hydroxy-5indole;TIMTEC-BB SBB004214;1H-INDOL-5-OL;5-HYDROXYINDOLE;5-INDOLOL;INDOL-5-OL CAS: 1953-54-4 MF: C8H7NO MW: 133.15

5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Hydroxyindole

Cas:1953-54-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5-Hydroxyindole CAS NO.1953-54-4 CAS NO.1953-54-4

Cas:1953-54-4

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

5-Hydroxyindole

Cas:1953-54-4

Min.Order:0

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat

5-Hydroxyindole

Cas:1953-54-4

Min.Order:1 Kilogram

FOB Price: $777.0 / 888.0

Type:Lab/Research institutions

inquiry

Synthetic route

1-[(E)-2-(5-benzyloxy-2-nitrophenyl)vinyl]pyrrolidine
153805-85-7

1-[(E)-2-(5-benzyloxy-2-nitrophenyl)vinyl]pyrrolidine

A

indol-5-ol
1953-54-4

indol-5-ol

B

5-benzyloxy-1H-indole
1215-59-4

5-benzyloxy-1H-indole

Conditions
ConditionsYield
With hydrogen; 5% rhodium-on-charcoal; iron(II) acetate In tetrahydrofuran at 20℃; for 9h;A 1%
B 99%
With hydrogen; 5% rhodium-on-charcoal; tris(acetylacetonato)cobalt In tetrahydrofuran at 20℃; for 15h;A 3%
B 96%
With hydrogen; 5% rhodium-on-charcoal; nickel(II) nitrate In tetrahydrofuran; water at 20℃; for 23h;A 0.4%
B 93%
1H-indole-5-boronic acid
144104-59-6

1H-indole-5-boronic acid

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With water; dihydrogen peroxide In ethanol at 20℃; for 0.0166667h; Green chemistry;91%
With C11H12ClNOPtS2; triethylamine In N,N-dimethyl-formamide at 20℃; Irradiation;48%
With Oxone; potassium phosphate; 2-(biphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In water at 70℃; for 1h; chemoselective reaction;
5-benzyloxy-1H-indole
1215-59-4

5-benzyloxy-1H-indole

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With ammonium formate; palladium on activated charcoal In ethanol Ambient temperature;90%
With Pd(0)EnCat; ammonium formate In N,N-dimethyl-formamide at 80℃; for 0.166667h; Irradiation; microwave;90%
With palladium on activated charcoal; ethyl acetate Hydrogenation;
oxygen
80937-33-3

oxygen

1H-indole-5-boronic acid
144104-59-6

1H-indole-5-boronic acid

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With triethanolamine In water at 20℃; for 18h; Sonication; Irradiation; Green chemistry;84%
5-(prop-2-ynynloxy)indole
153969-91-6

5-(prop-2-ynynloxy)indole

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With palladium on activated charcoal; ethanolamine In water at 80℃; Inert atmosphere;77%
5-methoxylindole
1006-94-6

5-methoxylindole

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With 1-N-ferrocenylmethyl benzimidazole tagged polymer In N,N-dimethyl-formamide Reflux;71%
With aluminium trichloride; benzene
With trimethylammonium heptachlorodialuminate In dichloromethane Heating;
5-benzyloxy-2-nitrophenylacetonitrile
15566-30-0

5-benzyloxy-2-nitrophenylacetonitrile

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With hydrogen; acetic acid; 10% palladium on active carbon In ethanol under 2280 Torr; for 2h; Ambient temperature;70%
C8H7NO

C8H7NO

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With silver nitrate In dichloromethane at 20℃; for 1.5h;64%
methyl (4S,6R)-6-(5-hydroxy-1H-indol-3-yl)-7-hydroxy-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indole-4-carboxylate

methyl (4S,6R)-6-(5-hydroxy-1H-indol-3-yl)-7-hydroxy-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indole-4-carboxylate

A

indol-5-ol
1953-54-4

indol-5-ol

B

methyl (S)-7-hydroxy-3,4-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylate

methyl (S)-7-hydroxy-3,4-dihydro-1H-azepino[5,4,3-cd]indole-4-carboxylate

Conditions
ConditionsYield
In methanol for 10h; Reflux;A 53%
B 61%
2,3-Dihydro-1H-indol-5-ol
172078-33-0

2,3-Dihydro-1H-indol-5-ol

nitrobenzene
98-95-3

nitrobenzene

A

indol-5-ol
1953-54-4

indol-5-ol

B

aniline
62-53-3

aniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 57%
B 60%
indole
120-72-9

indole

A

6-hydroxy-1H-indole
2380-86-1

6-hydroxy-1H-indole

B

indol-5-ol
1953-54-4

indol-5-ol

C

7-Indolol
2380-84-9

7-Indolol

D

1H-indol-4-ol
2380-94-1

1H-indol-4-ol

Conditions
ConditionsYield
With dihydrogen peroxide; edetate disodium; iron(II) sulfate; ascorbic acid phosphate buffer (pH=7.2);A 10%
B 30%
C 10%
D 50%
2,6-dimethylnitrobenzene
81-20-9

2,6-dimethylnitrobenzene

2,3-Dihydro-1H-indol-5-ol
172078-33-0

2,3-Dihydro-1H-indol-5-ol

A

indol-5-ol
1953-54-4

indol-5-ol

B

2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 35%
B 33%
indole
120-72-9

indole

A

6-hydroxy-1H-indole
2380-86-1

6-hydroxy-1H-indole

B

indol-5-ol
1953-54-4

indol-5-ol

C

1H-indol-4-ol
2380-94-1

1H-indol-4-ol

Conditions
ConditionsYield
With hydrogen fluoride; dihydrogen peroxide; antimony pentafluoride at -20℃; for 0.05h;A 10%
B 20%
C 5%
1H-indol-5-yl acetate
5594-91-2

1H-indol-5-yl acetate

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With methanol; ammonia
5-hydroxyindole-2-carboxylic acid
21598-06-1

5-hydroxyindole-2-carboxylic acid

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With copper at 250℃;
With copper; glycerol at 225 - 230℃;
2-amino-3-(2,5-dihydroxyphenyl)propanoic acid
26122-90-7

2-amino-3-(2,5-dihydroxyphenyl)propanoic acid

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With water; sodium hydrogencarbonate; potassium hexacyanoferrate(III)
3h electrolysis at +0.2 V, pH 7.02; Multistep reaction;
1H-indol-5-yl acetate
5594-91-2

1H-indol-5-yl acetate

A

indol-5-ol
1953-54-4

indol-5-ol

B

1-(5-Hydroxy-1H-indol-4-yl)-ethanone
126963-80-2

1-(5-Hydroxy-1H-indol-4-yl)-ethanone

C

1-(5-Hydroxy-1H-indol-6-yl)-ethanone
126963-81-3

1-(5-Hydroxy-1H-indol-6-yl)-ethanone

Conditions
ConditionsYield
Irradiation;A 36 % Chromat.
B 40 % Chromat.
C 6 % Chromat.
Product distribution; Mechanism; Irradiation;A 36 % Chromat.
B 40 % Chromat.
C 6 % Chromat.
2,5-dihydroxyphenylethylamine
21581-41-9

2,5-dihydroxyphenylethylamine

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
1h electrolysis at +0.2 V, pH 7.48 buffer; Multistep reaction;
With ammonium hydroxide; air In methanol Yield given;
2,3-Dihydro-indol-5-one

2,3-Dihydro-indol-5-one

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With palladium on activated charcoal In benzene for 3h; Heating; Yield given;
N,N,N',N'-tetramethyl-para-phenylenediamine
100-22-1

N,N,N',N'-tetramethyl-para-phenylenediamine

5-Hydroxyindole radical
80792-63-8

5-Hydroxyindole radical

A

indol-5-ol
1953-54-4

indol-5-ol

B

N,N,N',N'-Tetramethyl-benzene-1,4-diamine
100-22-1

N,N,N',N'-Tetramethyl-benzene-1,4-diamine

Conditions
ConditionsYield
With potassium hydroxide In water Rate constant; Equilibrium constant; Irradiation;
4-(N,N-dimethylamino)phenol
619-60-3

4-(N,N-dimethylamino)phenol

5-Hydroxyindole radical
80792-63-8

5-Hydroxyindole radical

A

indol-5-ol
1953-54-4

indol-5-ol

B

4-(N,N-dimethylamino)phenoxyl radical
54737-34-7

4-(N,N-dimethylamino)phenoxyl radical

Conditions
ConditionsYield
With potassium hydroxide In water Rate constant; Equilibrium constant; Irradiation;
hydrobromide of 2,5-dihydroxy-phenethylamine

hydrobromide of 2,5-dihydroxy-phenethylamine

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With water; silver(I) chloride und Behandeln der Reaktionsloesung mit Kalium-hexacianoferrat(III) und Natriumhydrogencarbonat;
5-methoxylindole
1006-94-6

5-methoxylindole

N-methyl-aniline hydrobromide

N-methyl-aniline hydrobromide

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
at 220℃;
sodium-salt of/the/ <5-benzyloxy-2-nitro-phenyl>-pyruvic acid

sodium-salt of/the/ <5-benzyloxy-2-nitro-phenyl>-pyruvic acid

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
With hydroxylamine hydrochloride Erwaermen des erhaltenen Oxims mit Essigsaeure und Acetanhydrid und Hydrieren des Reaktionsprodukts in Aethylacetat an Palladium/Kohle.;
water
7732-18-5

water

1-(2,5-dihydroxyphenyl)-2-aminoethane hydrochloride
88440-94-2

1-(2,5-dihydroxyphenyl)-2-aminoethane hydrochloride

K3

K3

NaHCO3

NaHCO3

indol-5-ol
1953-54-4

indol-5-ol

[4-(benzyloxy)phenyl]hydrazine
51145-58-5

[4-(benzyloxy)phenyl]hydrazine

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2SO4 / methanol / 3 h / Heating
2: MeOH / Pd/C / 20 °C / 760 Torr
View Scheme
5-Hydroxy-2-coumaranone
2688-48-4

5-Hydroxy-2-coumaranone

A

indol-5-ol
1953-54-4

indol-5-ol

B

phenyl-n-hexyl halide

phenyl-n-hexyl halide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 66 percent / NH3 / tetrahydrofuran
2: BH3 / tetrahydrofuran
3: aq. NH3, air / methanol
View Scheme
Homogentisinsaeureamid
5663-54-7

Homogentisinsaeureamid

A

indol-5-ol
1953-54-4

indol-5-ol

B

phenyl-n-hexyl halide

phenyl-n-hexyl halide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: BH3 / tetrahydrofuran
2: aq. NH3, air / methanol
View Scheme
4-nitro-phenol
100-02-7

4-nitro-phenol

PtO2

PtO2

indol-5-ol
1953-54-4

indol-5-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: anhydrous K2CO3 / dimethylformamide
2: 67 percent / tBuOK / dimethylformamide / 0.5 h / -20 - -10 °C
3: 70 percent / H2, acetic acid / Pd/C (10percent Pd) / ethanol / 2 h / 2280 Torr / Ambient temperature
View Scheme
indol-5-ol
1953-54-4

indol-5-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

5-(tert-butyl-dimethyl-silanyloxy)-1H-indole
106792-38-5

5-(tert-butyl-dimethyl-silanyloxy)-1H-indole

Conditions
ConditionsYield
With 1H-imidazole In DMF (N,N-dimethyl-formamide) at 20℃; for 20h;100%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 20h;100%
With 1H-imidazole In DMF (N,N-dimethyl-formamide) at 20℃; for 20h;100%
indol-5-ol
1953-54-4

indol-5-ol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

1H-indol-5-yl methanesulfonate
128810-31-1

1H-indol-5-yl methanesulfonate

Conditions
ConditionsYield
In dichloromethane99%
With triethylamine In dichloromethane at 0 - 20℃;83%
With dmap; triethylamine In dichloromethane at 0℃; for 5h;69%
With triethylamine In dichloromethane
indol-5-ol
1953-54-4

indol-5-ol

tert-butyl (1-benzyl-7-methyl-2-oxoindolin-3-ylidene)carbamate
1568924-02-6

tert-butyl (1-benzyl-7-methyl-2-oxoindolin-3-ylidene)carbamate

C29H29N3O4

C29H29N3O4

Conditions
ConditionsYield
With 3-(3,5-bis-trifluoromethyl-phenylamino)-4-{[(S)-(6-methoxy-quinolin-4-yl)-((R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methyl]-amino}-cyclobut-3-ene-1,2-dione In toluene at 25℃; for 12h; Friedel-Crafts Alkylation; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

C15H13BrF3NO3

C15H13BrF3NO3

tert-butyl (2-bromo-6-((8R,9S)-7-oxo-9-(trifluoromethyl)-3,7,8,9-tetrahydropyrano[3,2-e]indol-8-yl)phenyl)carbamate

tert-butyl (2-bromo-6-((8R,9S)-7-oxo-9-(trifluoromethyl)-3,7,8,9-tetrahydropyrano[3,2-e]indol-8-yl)phenyl)carbamate

Conditions
ConditionsYield
With C32H28F6N4O3 In dichloromethane at -30℃; for 35h; Friedel-Crafts Alkylation; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

N-(2,5-dichloro-4-oxo-2,5-cyclohexadien-1-ylidene)-4-methylbenzenesulfonamide

N-(2,5-dichloro-4-oxo-2,5-cyclohexadien-1-ylidene)-4-methylbenzenesulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-4-methylbenzenesulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With 1,1’-((1R,2R)-cyclohexane-1,2-diyl)bis(3-(3,5-bis(trifluoromethyl)phenyl) thiourea) In toluene at -40℃; for 12h; Catalytic behavior; Concentration; Reagent/catalyst; Solvent; enantioselective reaction;99%
With (R)-3,3'-bis(9-anthracenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate In ethyl acetate at -30℃; enantioselective reaction;58%
indol-5-ol
1953-54-4

indol-5-ol

N-(2,5-dichloro-4-oxo-2,5-cyclohexadien-1-ylidene)-4-methylbenzenesulfonamide

N-(2,5-dichloro-4-oxo-2,5-cyclohexadien-1-ylidene)-4-methylbenzenesulfonamide

N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-4-methylbenzenesulfonamide

N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With 1,1’-((1R,2R)-cyclohexane-1,2-diyl)bis(3-(3,5-bis(trifluoromethyl)phenyl) thiourea) In 1,2-dichloro-ethane at -20℃; for 12h; Catalytic behavior; Solvent; Temperature; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

C13H9Cl2NO3S

C13H9Cl2NO3S

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-2-methylbenzenesulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-2-methylbenzenesulfonamide

Conditions
ConditionsYield
With 1,1’-((1R,2R)-cyclohexane-1,2-diyl)bis(3-(3,5-bis(trifluoromethyl)phenyl) thiourea) In toluene at -40℃; for 12h; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

C13H9Cl2NO3S

C13H9Cl2NO3S

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-3-methylbenzenesulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)-3-methylbenzenesulfonamide

Conditions
ConditionsYield
With 1,1’-((1R,2R)-cyclohexane-1,2-diyl)bis(3-(3,5-bis(trifluoromethyl)phenyl) thiourea) In toluene at -40℃; for 12h; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

N-[2,5-Dichloro-4-oxo-cyclohexa-2,5-dien-(Z)-ylidene]-benzenesulfonamide
102117-89-5

N-[2,5-Dichloro-4-oxo-cyclohexa-2,5-dien-(Z)-ylidene]-benzenesulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)benzenesulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)benzenesulfonamide

Conditions
ConditionsYield
With 1,1’-((1R,2R)-cyclohexane-1,2-diyl)bis(3-(3,5-bis(trifluoromethyl)phenyl) thiourea) In toluene at -40℃; for 12h; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

C16H9Cl2NO3S

C16H9Cl2NO3S

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)naphthalene-1-sulfonamide

(S)-N-(2,5-dichloro-4-hydroxy-3-(5-hydroxy-1H-indol-4-yl)phenyl)naphthalene-1-sulfonamide

Conditions
ConditionsYield
With 1,1’-((1R,2R)-cyclohexane-1,2-diyl)bis(3-(3,5-bis(trifluoromethyl)phenyl) thiourea) In toluene at -40℃; for 12h; enantioselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

1-iodo-butane
542-69-8

1-iodo-butane

carbon monoxide
201230-82-2

carbon monoxide

C13H15NO2

C13H15NO2

Conditions
ConditionsYield
With rhodium(III) chloride; 1,3-bis-(diphenylphosphino)propane; sodium carbonate; sodium bromide In 1,4-dioxane at 120℃; under 750.075 Torr; for 24h; Inert atmosphere; chemoselective reaction;99%
indol-5-ol
1953-54-4

indol-5-ol

1-iodo-propane
107-08-4

1-iodo-propane

5-propyloxy-1H-indole
147405-80-9

5-propyloxy-1H-indole

Conditions
ConditionsYield
With potassium carbonate In acetone Heating;98%
With potassium carbonate In acetone for 72h; Inert atmosphere; Schlenk technique; Reflux;84%
In N,N-dimethyl-formamide
indol-5-ol
1953-54-4

indol-5-ol

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

5-indolyl tert-butyl carbonate

5-indolyl tert-butyl carbonate

Conditions
ConditionsYield
With zinc diacetate at 50℃; for 17.33h;98%
indol-5-ol
1953-54-4

indol-5-ol

tert-butyl (1-benzyl-6-chloro-2-oxoindolin-3-ylidene)carbamate
1426931-83-0

tert-butyl (1-benzyl-6-chloro-2-oxoindolin-3-ylidene)carbamate

C28H26ClN3O4

C28H26ClN3O4

Conditions
ConditionsYield
With 3-(3,5-bis-trifluoromethyl-phenylamino)-4-{[(S)-(6-methoxy-quinolin-4-yl)-((R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methyl]-amino}-cyclobut-3-ene-1,2-dione In toluene at 25℃; for 12h; Friedel-Crafts Alkylation; enantioselective reaction;98%
indol-5-ol
1953-54-4

indol-5-ol

2-(2-nitroethenyl)thiophene
874-84-0, 34312-77-1

2-(2-nitroethenyl)thiophene

(S)-4-(2-nitro-1-(thiophen-2-yl)ethyl)-1H-indol-5-ol

(S)-4-(2-nitro-1-(thiophen-2-yl)ethyl)-1H-indol-5-ol

Conditions
ConditionsYield
With 3-((1R,2R)-2-(piperidin-1-yl)cyclohexylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione In chloroform at 4℃; Friedel-Crafts Alkylation; enantioselective reaction;98%
4,6-dichloropyrimidine
1193-21-1

4,6-dichloropyrimidine

indol-5-ol
1953-54-4

indol-5-ol

5-(6-chloropyrimidin-4-yloxy)-1H-indole
630126-16-8

5-(6-chloropyrimidin-4-yloxy)-1H-indole

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 1h;97.4%
With sodium hydroxide In water; acetone at 65℃; for 1.16667h;
Stage #1: indol-5-ol With sodium hydroxide In water at -10 - 10℃;
Stage #2: 4,6-dichloropyrimidine In water; acetone at 0℃; for 1.58333h;
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 1h;
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 12h;
indol-5-ol
1953-54-4

indol-5-ol

ethyl bromoacetate
105-36-2

ethyl bromoacetate

ethyl 2-((1H-indol-5-yl)oxy)acetate
53232-66-9

ethyl 2-((1H-indol-5-yl)oxy)acetate

Conditions
ConditionsYield
With potassium carbonate In butanone at 89℃;97%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;82%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;82%
indol-5-ol
1953-54-4

indol-5-ol

1-(fluorosulfonyl)-1H-indol-5-yl sulfurofluoridate

1-(fluorosulfonyl)-1H-indol-5-yl sulfurofluoridate

Conditions
ConditionsYield
Stage #1: indol-5-ol With N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 0.166667h;
Stage #2: With fluorosulfonyl fluoride In acetonitrile at 20℃; for 5h; chemoselective reaction;
97%
With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 18h;97%
indol-5-ol
1953-54-4

indol-5-ol

tert-butyl (1,3-dioxo-2-phenyl-2,3-dihydroisoquinolin-4(1H)-ylidene)carbamate

tert-butyl (1,3-dioxo-2-phenyl-2,3-dihydroisoquinolin-4(1H)-ylidene)carbamate

(S)-tert-butyl (4-(5-hydroxy-1H-indol-3-yl)-1,3-dioxo-2-phenyl-1,2,3,4-tetrahydroisoquinolin-4-yl)carbamate

(S)-tert-butyl (4-(5-hydroxy-1H-indol-3-yl)-1,3-dioxo-2-phenyl-1,2,3,4-tetrahydroisoquinolin-4-yl)carbamate

Conditions
ConditionsYield
With (11aR)-3,7-di-9-anthracenyl-10,11,12,13-tetrahydro-5-hydroxy-5-oxide diindeno[7,1de:10,70-fg][1,3,2] dioxaphosphocin In toluene at 60℃; for 4h; enantioselective reaction;97%
indol-5-ol
1953-54-4

indol-5-ol

allyl alcohol
107-18-6

allyl alcohol

3-allyl-5-hydroxyindole

3-allyl-5-hydroxyindole

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); triethyl borane In tetrahydrofuran; hexane at 50℃; for 24h;96%
With {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; C21H10F12NOP In toluene at 50℃; for 20h; Inert atmosphere;84%
indol-5-ol
1953-54-4

indol-5-ol

2-amino-5-hydroxybenzoic acid
394-31-0

2-amino-5-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: indol-5-ol With bromamine B; sodium hydroxide; palladium dichloride In water; acetonitrile at 60℃; for 3.33333h; pH=12;
Stage #2: In water Acidic conditions;
96%
With ruthenium trichloride; osmium(VIII) oxide; bromamine B; sodium hydroxide In water; acetonitrile at 39.84℃; for 4.33333h;96%
indol-5-ol
1953-54-4

indol-5-ol

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

C23H17FN2O2
1228150-85-3

C23H17FN2O2

Conditions
ConditionsYield
With cerium(III) chloride heptahydrate at 20℃; for 0.0333333h; neat (no solvent);96%
indol-5-ol
1953-54-4

indol-5-ol

1,2,3,4-tetrahydroisoquinoline
91-21-4

1,2,3,4-tetrahydroisoquinoline

fluorenone imine
4440-33-9

fluorenone imine

3-(2-(9H-fluoren-9-yl)-1,2,3,4-tetrahydroisoquinolin-1-yl)-1H-indol-5-ol

3-(2-(9H-fluoren-9-yl)-1,2,3,4-tetrahydroisoquinolin-1-yl)-1H-indol-5-ol

Conditions
ConditionsYield
In neat (no solvent) at 90 - 100℃; for 44h; Sealed tube;96%
indol-5-ol
1953-54-4

indol-5-ol

N-methylacridinium iodide
948-43-6

N-methylacridinium iodide

9-(5-hydroxy-1H-indol-3-yl)-10-methylacridinium iodide

9-(5-hydroxy-1H-indol-3-yl)-10-methylacridinium iodide

Conditions
ConditionsYield
Stage #1: indol-5-ol; N-methylacridinium iodide With titanium(IV) oxide In butan-1-ol for 0.0833333h; Sonication; Green chemistry;
Stage #2: In butan-1-ol at 20℃; for 5h; Irradiation; Green chemistry;
96%
indol-5-ol
1953-54-4

indol-5-ol

propargyl bromide
106-96-7

propargyl bromide

5-(prop-2-ynynloxy)indole
153969-91-6

5-(prop-2-ynynloxy)indole

Conditions
ConditionsYield
With caesium carbonate In acetone at 20℃;95%
With caesium carbonate In acetone Ambient temperature;87%
With potassium carbonate In toluene Heating;
indol-5-ol
1953-54-4

indol-5-ol

(2-nitroethenyl)benzene
102-96-5

(2-nitroethenyl)benzene

5-hydroxy-3-(2-nitro-1-phenylethyl)-1H-indole

5-hydroxy-3-(2-nitro-1-phenylethyl)-1H-indole

Conditions
ConditionsYield
With C84H114F9N3O12S3 In water at 37℃; for 16h; Michael Addition;95%
With C99H126N6O18S3 In methanol at 50℃; for 24h; Catalytic behavior; Solvent; Michael Addition;91%
With N-Bromosuccinimide In dichloromethane at 40℃; for 5h; Friedel Crafts alkylation;89%
With MoS2 supported on graphitic carbon nitride nanocomposit In water at 55℃; for 12h; Michael Addition; Green chemistry;
indol-5-ol
1953-54-4

indol-5-ol

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

C24H20N2O3
1228150-84-2

C24H20N2O3

Conditions
ConditionsYield
With cerium(III) chloride heptahydrate at 20℃; for 0.0333333h; neat (no solvent);95%
indol-5-ol
1953-54-4

indol-5-ol

sodium 1-(tert-butoxycarbonyl) azetidine-3-sulfinate

sodium 1-(tert-butoxycarbonyl) azetidine-3-sulfinate

tert-butyl 3-((5-hydroxy-1H-indol-2-yl)sulfonyl)azetidine-1-carboxylate

tert-butyl 3-((5-hydroxy-1H-indol-2-yl)sulfonyl)azetidine-1-carboxylate

Conditions
ConditionsYield
With iodine In methanol at 20℃; for 24h; regioselective reaction;95%
indol-5-ol
1953-54-4

indol-5-ol

4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

3,3''-((4-nitrophenyl)methylene)bis(1H-indol-5-ol)
1027786-80-6

3,3''-((4-nitrophenyl)methylene)bis(1H-indol-5-ol)

Conditions
ConditionsYield
With benzenesulfonic acid In acetonitrile at 20℃; for 0.166667h; Sonication;95%

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