Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:22515-18-0
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:22515-18-0
Min.Order:1 Kilogram
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inquiryHigh quality 4,4-Difluorocyclohexanone CAS 22515-18-0 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/F
Cas:22515-18-0
Min.Order:10 Kilogram
FOB Price: $10.0
Type:Trading Company
inquiry4,4-DIFLUOROCYCLOHEXANONE Basic information Product Name: 4,4-DIFLUOROCYCLOHEXANONE Synonyms: 4,4-DIFLUOROCYCLOHEXANONE;4,4-Difluorocyclohexan-1-one;1,1,-Difluoro-4
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Cas:22515-18-0
Min.Order:1 Metric Ton
Negotiable
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:22515-18-0
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:22515-18-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:22515-18-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:22515-18-0
Min.Order:1 Kilogram
FOB Price: $88.0 / 95.0
Type:Trading Company
inquiry4,4-DIFLUOROCYCLOHEXANONE CAS:22515-18-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:22515-18-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:22515-18-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
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Cas:22515-18-0
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:22515-18-0
Min.Order:0 Metric Ton
Negotiable
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:22515-18-0
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:22515-18-0
Min.Order:0
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Type:Lab/Research institutions
inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:22515-18-0
Min.Order:100 Gram
Negotiable
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:22515-18-0
Min.Order:10 Gram
FOB Price: $100.0
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:22515-18-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry4,4-DIFLUOROCYCLOHEXANONE Basic information Product Name: 4,4-DIFLUOROCYCLOHEXANONE Synonyms: 4,4-DIFLUOROCYCLOHEXANONE;4,4-Difluorocyclohexan-1-one;1,1,-Difluoro-4-oxocyclohexane;4,4-difluro-cyclohexanone;4,4-Difluorocyclohexanone;Cyclohexano
Cas:22515-18-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
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Cas:22515-18-0
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:22515-18-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryADVANTAGE 1.Professional: More than 10 years chemical exporting experience. We have produced chemical more than fifteen years, 95% products are for export . More than 10 years chemical exporting experience. Good and stabilized factory price. 2.Reaso
Cas:22515-18-0
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:22515-18-0
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryWuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma
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8,8-difluoro-1,4-dioxaspiro[4,5]decane
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
With hydrogenchloride; water at 100℃; for 12h; | 93% |
With hydrogenchloride In acetone for 1h; Inert atmosphere; | 80% |
With hydrogenchloride In water at 100℃; for 3h; | 71% |
4,4-difluoroheptanedioic acid diethyl ester
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
(i) NaOEt, EtOH, (ii) aq. KOH; Multistep reaction; |
4-oxopimelate
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: SF4 / CH2Cl2; H2O 2: (i) NaOEt, EtOH, (ii) aq. KOH View Scheme |
3-(fur-2-yl)crotonic acid
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: HCl / Heating 2: SF4 / CH2Cl2; H2O 3: (i) NaOEt, EtOH, (ii) aq. KOH View Scheme |
cyclohexanedione monoethylene ketal
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: difluoro-4-morpholinylsulfonium tetrafluoroborate; triethylamine tris(hydrogen fluoride) / dichloromethane / 24 h / 20 °C / Inert atmosphere 2: hydrogenchloride / acetone / 1 h / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1.1: morpholinosulfur trifluoride / dichloromethane / 72 h / 0 - 20 °C / Inert atmosphere 1.2: 24 h 2.1: hydrogenchloride / water / 3 h / 100 °C View Scheme | |
Multi-step reaction with 2 steps 1: (bis-(2-methoxyethyl)amino)sulfur trufluoride; ethanol / dichloromethane / 2 h / 20 °C / Inert atmosphere 2: toluene-4-sulfonic acid / water; acetone / 24 h / Reflux View Scheme | |
Stage #1: cyclohexanedione monoethylene ketal With ethanol; (bis-(2-methoxyethyl)amino)sulfur trufluoride In dichloromethane at 20℃; for 2h; Inert atmosphere; Stage #2: With toluene-4-sulfonic acid In water; acetone for 24h; Reflux; | |
Multi-step reaction with 2 steps 1.1: diethylamino-sulfur trifluoride / dichloromethane / 4 h / 0 - 35 °C 1.2: 20 °C 2.1: water; hydrogenchloride / 12 h / 100 °C View Scheme |
trimethylsilyl cyanide
4,4-difluorocyclohexanone
4,4-difluoro-1-[(trimethylsilyl)oxy]cyclohexane carbonitrile
Conditions | Yield |
---|---|
With copper(II) bis(trifluoromethanesulfonate) In dichloromethane at 20℃; | 100% |
With zinc(II) iodide In dichloromethane at 0 - 20℃; for 1h; | |
With zinc(II) iodide In dichloromethane at 0 - 20℃; for 1h; | 1.5 g |
4,4-difluorocyclohexanone
methyl (triphenylphosphoranylidene)acetate
methyl 2-(4,4-difluorocyclohexylidene)acetate
Conditions | Yield |
---|---|
In tetrahydrofuran at 65℃; for 20h; Schlenk technique; Inert atmosphere; | 100% |
4,4-difluorocyclohexanone
4,4-difluorocyclohexanol
Conditions | Yield |
---|---|
With methanol; sodium tetrahydroborate at 0 - 25℃; for 2h; | 99% |
With methanol; sodium tetrahydroborate at 20℃; for 1h; | 94% |
With methanol; sodium tetrahydroborate for 1h; Inert atmosphere; Cooling with ice; | 91% |
4,4-difluorocyclohexanone
ethyl (triphenylphosphoranylidene)acetate
ethyl 2-(4,4-difluorocyclohexylidene)-acetate
Conditions | Yield |
---|---|
In toluene at 100℃; for 16h; | 99% |
In tetrahydrofuran at 65℃; Inert atmosphere; | 97% |
t-butoxycarbonylhydrazine
4,4-difluorocyclohexanone
N'-(4,4-difluorocyclohexyl)hydrazinecarboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With hydrogen; acetic acid; platinum(IV) oxide In isopropyl alcohol at 20℃; under 2585.81 Torr; for 12h; | 98% |
With hydrogen; acetic anhydride; platinum(IV) oxide In isopropyl alcohol at 20℃; under 2585.81 Torr; for 12h; | 98% |
With hydrogen; platinum(IV) oxide; acetic acid In isopropyl alcohol at 20℃; under 2585.81 Torr; for 12h; | 98% |
1-phenylmethylpiperazine
trimethylsilyl cyanide
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
Stage #1: 1-phenylmethylpiperazine; 4,4-difluorocyclohexanone With zinc(II) iodide In methanol; toluene at 25℃; for 1h; Inert atmosphere; Stage #2: trimethylsilyl cyanide In methanol; toluene for 16h; Inert atmosphere; Heating; | 97% |
trimethyl phosphonoacetate
4,4-difluorocyclohexanone
methyl 2-(4,4-difluorocyclohexylidene)acetate
Conditions | Yield |
---|---|
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 4℃; for 1h; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran; mineral oil at 0 - 20℃; | 95% |
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0 - 5℃; for 1h; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran at 0 - 27℃; for 15h; | 57% |
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 5℃; for 1h; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran at 5 - 20℃; Stage #3: With water In tetrahydrofuran |
4,4-difluorocyclohexanone
phenylhydrazine hydrochloride
3,3-difluoro-2,3,4,9-tetrahydro-1H-carbazole
Conditions | Yield |
---|---|
With acetic acid at 140℃; Inert atmosphere; | 95% |
With silica gel at 20℃; for 3h; Fischer Indole Synthesis; Milling; | 46% |
4,4-difluorocyclohexanone
vinyl magnesium bromide
Conditions | Yield |
---|---|
In tetrahydrofuran at 0℃; for 1h; Grignard Reaction; Inert atmosphere; | 94% |
4,4-difluorocyclohexanone
N,N-dimethyl-formamide dimethyl acetal
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 100℃; for 18h; | 92% |
4,4-difluorocyclohexanone
N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester
Conditions | Yield |
---|---|
Stage #1: N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester With 1,8-diazabicyclo[5.4.0]undec-7-ene In 1-methyl-pyrrolidin-2-one at 15℃; for 0.5h; Wittig-Horner Reaction; Large scale; Stage #2: 4,4-difluorocyclohexanone In 1-methyl-pyrrolidin-2-one at 10 - 20℃; for 12h; Large scale; | 90% |
Stage #1: N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 10 - 35℃; for 0.5h; Stage #2: 4,4-difluorocyclohexanone In acetonitrile at 10 - 35℃; | 84% |
4,4-difluorocyclohexanone
ethyl 2-((tert-butyldimethylsilyl)oxy)-2-(diethoxyphosphoryl)acetate
C16H28F2O3Si
Conditions | Yield |
---|---|
Stage #1: ethyl 2-((tert-butyldimethylsilyl)oxy)-2-(diethoxyphosphoryl)acetate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran at -78 - 20℃; | 88% |
sodium cyanide
4,4-difluorocyclohexanone
8,8-difluoro-1,3-diazaspiro[4.5]decane-2,4-dione
Conditions | Yield |
---|---|
With ammonium carbonate In water at 0 - 60℃; for 26h; | 88% |
4,4-difluorocyclohexanone
N-benzyl-3-butenylamine
Conditions | Yield |
---|---|
With Ir(dMeppy)3; cyclohexa-1,4-diene; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; propionic acid In dichloromethane at 20℃; for 48h; Molecular sieve; Sealed tube; Inert atmosphere; Irradiation; | 87% |
4,4-difluorocyclohexanone
Ethyl 2-bromopropionate
Conditions | Yield |
---|---|
With zinc In 1,4-dioxane at 100℃; for 24h; | 85% |
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
Stage #1: 4,4-difluorocyclohexanone; tert-butyl (R)-3-(((4-(aminomethyl)benzyl)((S)-5,6,7,8-tetrahydroquinolin-8-yl)amino)methyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate With acetic acid In dichloromethane at 20℃; for 2.5h; Inert atmosphere; Stage #2: With sodium tris(acetoxy)borohydride In dichloromethane at 20℃; Inert atmosphere; | 84% |
Conditions | Yield |
---|---|
With ammonium acetate In toluene at 160℃; for 3h; | 84% |
4,4-difluorocyclohexanone
tert-butyl diethylphosphonoacetate
tert-butyl 2-(4,4-difluorocyclohexylidene)acetate
Conditions | Yield |
---|---|
Stage #1: tert-butyl diethylphosphonoacetate With sodium hydride In tetrahydrofuran at 0 - 20℃; for 0.5h; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran at 0 - 20℃; Inert atmosphere; | 83% |
4,4-difluorocyclohexanone
carbonic acid dimethyl ester
Conditions | Yield |
---|---|
Stage #1: 4,4-difluorocyclohexanone With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h; Stage #2: carbonic acid dimethyl ester In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 16h; | 83% |
4,4-difluorocyclohexanone
allylmagnesium bromide
Conditions | Yield |
---|---|
In tetrahydrofuran at 0℃; for 1h; Inert atmosphere; | 82% |
In tetrahydrofuran at -74 - -60℃; for 2.66667h; | 46% |
4,4-difluorocyclohexanone
trimethylsulphonium iodide
Conditions | Yield |
---|---|
Stage #1: trimethylsulphonium iodide With potassium tert-butylate In tetrahydrofuran at 15℃; for 0.5h; Inert atmosphere; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran at 15℃; for 16h; | 82% |
4,4-difluorocyclohexanone
trimethylsulfonium iodide
Conditions | Yield |
---|---|
Stage #1: trimethylsulfonium iodide With potassium tert-butylate In tetrahydrofuran at 15℃; for 0.5h; Inert atmosphere; Stage #2: 4,4-difluorocyclohexanone In tetrahydrofuran at 15℃; for 16h; Inert atmosphere; | 82% |
tert-Butoxybis(dimethylamino)methane
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
at 50℃; for 18h; | 82% |
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃; for 12h; | 81% |
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
With sulfuric acid In 1,4-dioxane at 100℃; for 8h; | 80% |
4,4-difluorocyclohexanone
Conditions | Yield |
---|---|
With sodium cyanoborohydride In methanol at 20℃; | 78.4% |
4,4-difluorocyclohexanone
(piperidin-4-yl)carbamic acid tert-butyl ester
tert-butyl (1-(4,4-difluorocyclohexyl)piperidin-4-yl)carbamate
Conditions | Yield |
---|---|
With acetic acid; tetramethylammonium triacetoxyborohydride In N,N-dimethyl-formamide | 78% |
Stage #1: 4,4-difluorocyclohexanone; (piperidin-4-yl)carbamic acid tert-butyl ester With acetic acid In tetrahydrofuran at 50℃; for 2h; Stage #2: With sodium tris(acetoxy)borohydride In tetrahydrofuran at 50℃; for 18h; |
4,4-difluorocyclohexanone
4-aminophenylacetic acid
3-hydroxy-2-butanon
Conditions | Yield |
---|---|
With acetic acid In ethanol at 100℃; for 4h; Inert atmosphere; Sealed tube; Microwave irradiation; | 78% |
Conditions | Yield |
---|---|
With formic acid; 10 mol% Pd(OH)2/C In water at 100℃; for 24h; Inert atmosphere; | 78% |
With formic acid; 10% palladium hydroxide on charcoal In water at 100℃; for 24h; Inert atmosphere; | 78% |
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