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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

L-Valine benzyl ester hydrochloride Manufacturer/High quality/Best price/In stock

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Leader Biochemical Group

About Product Technical Details L-Valine benzyl ester hydrochloride Chemical Properties Melting point 138 °C refractive index

China Largest factory Manufacturer Supply L-Valine benzyl ester hydrochloride CAS 2462-34-2

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

L-Valine benzyl ester hydrochloride CAS:2462-34-2

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $8.0 / 15.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

C12H18ClNO2 L-Valine benzyl ester hydrochloride 2462-34-2

Cas:2462-34-2

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 2462-34-2 with competitive price

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

2462-34-2 L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

L-Valine benzyl ester hydrochloride CAS:2462-34-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

L-Valine benzyl ester hydrochloride CAS:2462-34-2

Cas:2462-34-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2462-34-2

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

L-Valine benzyl ester hydrochloride manufacturer/supplier

Cas:2462-34-2

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

H-Val-Obzl.HCl cas no.2462-34-2 0.98

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

L-VALINE BENZYL ESTER HYDROCHLORIDE

Cas:2462-34-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

H-Val-OBzl.HCl

Cas:2462-34-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

C12H18ClNO2 L-Valine benzyl ester hydrochloride 2462-34-2

Cas:2462-34-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

C12H18ClNO2 L-Valine benzyl ester hydrochloride 2462-34-2

Cas:2462-34-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

C12H18ClNO2 L-Valine benzyl ester hydrochloride 2462-34-2

Cas:2462-34-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/H-Val-OBzl.HCl

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

C12H18ClNO2 L-Valine benzyl ester hydrochloride 2462-34-2

Cas:2462-34-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

L-Valine benzyl ester hydrochloride

Cas:2462-34-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

((S)-1-benzylcarbamoyl-2-methyl-propyl)-carbamic acid tert-butyl ester
66447-55-0

((S)-1-benzylcarbamoyl-2-methyl-propyl)-carbamic acid tert-butyl ester

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane at 20℃; Inert atmosphere;100%
Stage #1: ((S)-1-benzylcarbamoyl-2-methyl-propyl)-carbamic acid tert-butyl ester With trifluoroacetic acid at 20℃; for 1h;
Stage #2: With hydrogenchloride In 1,4-dioxane; water
85%
With hydrogenchloride In tetrahydrofuran; 1,4-dioxane at 0℃; for 12h; Inert atmosphere;
With hydrogenchloride In ethyl acetate at 20℃; for 5h;
L-valine
72-18-4

L-valine

benzyl alcohol
100-51-6

benzyl alcohol

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Stage #1: L-valine With hydrogenchloride; iron(III) chloride In 1,2-dichloro-ethane at 20℃; for 0.5h;
Stage #2: benzyl alcohol In dichloromethane for 3h; Concentration; Reflux;
98%
With thionyl chloride at 5℃; for 5.33333h; Heating;70%
Stage #1: L-valine; benzyl alcohol at 20 - 90℃;
Stage #2: With sodium carbonate In water pH=10;
Stage #3: With hydrogenchloride In diethyl ether
With thionyl chloride at 20℃; Cooling with ice; Inert atmosphere;
t-Boc-L-valine
13734-41-3

t-Boc-L-valine

polymer supported Naphthyl Rinkamino Gly peptide

polymer supported Naphthyl Rinkamino Gly peptide

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 85 percent / Et3N / dimethylformamide / 0 - 20 °C
2.1: TFA / 1 h / 20 °C
2.2: 85 percent / HCl / dioxane; H2O
View Scheme
L-valine
72-18-4

L-valine

Asp(Bzl)

Asp(Bzl)

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 100 percent / Et3N / dioxane; H2O
2.1: 85 percent / Et3N / dimethylformamide / 0 - 20 °C
3.1: TFA / 1 h / 20 °C
3.2: 85 percent / HCl / dioxane; H2O
View Scheme
L-valine
72-18-4

L-valine

benzyl chloride
100-44-7

benzyl chloride

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
at 90℃; for 5h; Ionic liquid; Inert atmosphere;
t-Boc-L-valine
13734-41-3

t-Boc-L-valine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere
1.2: 12 h / Inert atmosphere
2.1: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 12 h / 0 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C / Inert atmosphere
2: hydrogenchloride / 1,4-dioxane / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 16 h / 0 - 20 °C
2: hydrogenchloride / ethyl acetate / 5 h / 20 °C
View Scheme
benzyl bromide
100-39-0

benzyl bromide

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere
1.2: 12 h / Inert atmosphere
2.1: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 12 h / 0 °C / Inert atmosphere
View Scheme
(S)-N(1)-(p-methoxybenzyl)-6-isopropylpiperazine-2,5-dione
437768-95-1

(S)-N(1)-(p-methoxybenzyl)-6-isopropylpiperazine-2,5-dione

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: boron trifluoride diethyl etherate / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere
2.1: ammonium cerium (IV) nitrate / acetonitrile; water / 18 h / 20 °C
3.1: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
4.2: 18 h / -78 - 20 °C / Inert atmosphere
5.1: hydrogenchloride / acetonitrile; water / 18 h / 20 °C
View Scheme
C22H26N2O3

C22H26N2O3

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: ammonium cerium (IV) nitrate / acetonitrile; water / 18 h / 20 °C
2.1: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
3.2: 18 h / -78 - 20 °C / Inert atmosphere
4.1: hydrogenchloride / acetonitrile; water / 18 h / 20 °C
View Scheme
C14H18N2O2

C14H18N2O2

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
2.2: 18 h / -78 - 20 °C / Inert atmosphere
3.1: hydrogenchloride / acetonitrile; water / 18 h / 20 °C
View Scheme
(S)-2-isopropyl-3-benzyloxy-6-ethoxy-2,5-dihydropyrazine

(S)-2-isopropyl-3-benzyloxy-6-ethoxy-2,5-dihydropyrazine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
1.2: 18 h / -78 - 20 °C / Inert atmosphere
2.1: hydrogenchloride / acetonitrile; water / 18 h / 20 °C
View Scheme
(2S,5R)-2-isopropyl-3-benzyloxy-5-ethyl-6-ethoxy-2,5-dihydropyrazine

(2S,5R)-2-isopropyl-3-benzyloxy-5-ethyl-6-ethoxy-2,5-dihydropyrazine

A

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

B

ethyl (2R)-2-aminobutanoate hydrochloride
127641-80-9

ethyl (2R)-2-aminobutanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water; acetonitrile at 20℃; for 18h;
O-benzyl 2,2,2-trichloroacetimidate
81927-55-1

O-benzyl 2,2,2-trichloroacetimidate

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: boron trifluoride diethyl etherate / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere
2.1: ammonium cerium (IV) nitrate / acetonitrile; water / 18 h / 20 °C
3.1: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
4.2: 18 h / -78 - 20 °C / Inert atmosphere
5.1: hydrogenchloride / acetonitrile; water / 18 h / 20 °C
View Scheme
benzyl alcohol
100-51-6

benzyl alcohol

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 16 h / 0 - 20 °C
2: hydrogenchloride / ethyl acetate / 5 h / 20 °C
View Scheme
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

C20H23NO3
1076214-41-9

C20H23NO3

Conditions
ConditionsYield
With sodium carbonate In methanol at 20℃; for 18h;100%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(S)-3-methyl-2-(2-trifluoromethyl-acryloylamino)-butyric acid benzyl ester
587885-44-7

(S)-3-methyl-2-(2-trifluoromethyl-acryloylamino)-butyric acid benzyl ester

(S)-2-{2-[((S)-1-Benzyloxycarbonyl-2-methyl-propylamino)-methyl]-3,3,3-trifluoro-propionylamino}-3-methyl-butyric acid benzyl ester

(S)-2-{2-[((S)-1-Benzyloxycarbonyl-2-methyl-propylamino)-methyl]-3,3,3-trifluoro-propionylamino}-3-methyl-butyric acid benzyl ester

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In dichloromethane at 20℃; for 2h; aza-Michael addition;98%
(R)-N-Boc-3,5-dibenzoxyphenylglycine
1149740-71-5

(R)-N-Boc-3,5-dibenzoxyphenylglycine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

C39H44N2O7
1149740-78-2

C39H44N2O7

Conditions
ConditionsYield
With sodium hydrogencarbonate; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one In tetrahydrofuran at 0 - 20℃; Inert atmosphere;98%
With sodium hydrogencarbonate; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one In N,N-dimethyl-formamide at 0 - 20℃; for 25h;
Fmoc-Pro-OH
71989-31-6

Fmoc-Pro-OH

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(9H-fluoren-9-yl)methyl-(S)-2-(((S)-1-(benzyloxy)-3-methyl-1-oxobutan-2-yl)carbamoyl) pyrrolidine-1-carboxylate

(9H-fluoren-9-yl)methyl-(S)-2-(((S)-1-(benzyloxy)-3-methyl-1-oxobutan-2-yl)carbamoyl) pyrrolidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: L-valine benzyl ester hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Inert atmosphere;
Stage #2: Fmoc-Pro-OH With benzotriazol-1-ol In dichloromethane at 0℃; for 0.25h; Inert atmosphere;
Stage #3: With dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere;
98%
Stage #1: Fmoc-Pro-OH; L-valine benzyl ester hydrochloride With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 0.25h; Inert atmosphere;
Stage #2: With dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere;
98%
N-tert-butoxycarbonyl-L-methionine
2488-15-5

N-tert-butoxycarbonyl-L-methionine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Boc-Met-Val-OBn

Boc-Met-Val-OBn

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃; for 2h;97%
N-tert-butoxycarbonyl-L-phenylalanine
13734-34-4

N-tert-butoxycarbonyl-L-phenylalanine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

benzyl (tert-butoxycarbonyl)-L-phenylalanyl-L-valinate
136282-23-0

benzyl (tert-butoxycarbonyl)-L-phenylalanyl-L-valinate

Conditions
ConditionsYield
With C14H16B2O6 In toluene at 80℃; for 48h; Molecular sieve;97%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

2-tert-butoxycarbonylamino-succinic acid 1-benzotriazol-1-yl ester 4-cyclohexyl ester

2-tert-butoxycarbonylamino-succinic acid 1-benzotriazol-1-yl ester 4-cyclohexyl ester

Boc-Asp(OcHex)-Val-OBzl
152020-28-5

Boc-Asp(OcHex)-Val-OBzl

Conditions
ConditionsYield
With 4-methyl-morpholine In tetrahydrofuran at 20℃; for 24h; Substitution;96%
BOC-L-aspartic acid 4-benzyl ester
7536-58-5

BOC-L-aspartic acid 4-benzyl ester

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Boc-Asp(OBzl)-Val-OBzl
110863-06-4

Boc-Asp(OBzl)-Val-OBzl

Conditions
ConditionsYield
Stage #1: BOC-L-aspartic acid 4-benzyl ester With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran for 0.333333h; Cooling with ice;
Stage #2: L-valine benzyl ester hydrochloride With 4-methyl-morpholine In tetrahydrofuran at 20℃; for 24h;
96%
Stage #1: BOC-L-aspartic acid 4-benzyl ester With 1-hydroxybenzotriazol-hydrate; dicyclohexyl-carbodiimide In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: L-valine benzyl ester hydrochloride With 4-methyl-morpholine In tetrahydrofuran at 20℃; for 8h; pH=8.5; Further stages.;
95%
(S)-2-Hydroxy-3-methylbutanoic acid
17407-55-5

(S)-2-Hydroxy-3-methylbutanoic acid

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

L-O-valine-L-valine benzyl ester

L-O-valine-L-valine benzyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃;95%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In acetonitrile at 0 - 20℃;92%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃;92%
With potassium carbonate; dicyclohexyl-carbodiimide 1.) water, 2.) CH2Cl2, 15 deg C, 5 h; Yield given. Multistep reaction;
t-Boc-L-valine
13734-41-3

t-Boc-L-valine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(S)-benzyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-3-methylbutanoate
77443-49-3

(S)-benzyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-3-methylbutanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; Acylation;95%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

carbonochloridic acid, chloromethyl ester
22128-62-7

carbonochloridic acid, chloromethyl ester

(S)-2-chloromethoxycarbonylamino-3-methyl-butyric acid benzyl ester

(S)-2-chloromethoxycarbonylamino-3-methyl-butyric acid benzyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 0.5h;95%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole
124750-51-2

N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole

N-[(2'-(1-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl)methyl]-(L)-valine benzyl ester phosphite

N-[(2'-(1-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl)methyl]-(L)-valine benzyl ester phosphite

Conditions
ConditionsYield
Stage #1: L-valine benzyl ester hydrochloride With sodium hydroxide In water; ethyl acetate for 0.333333h; pH=10 - 12;
Stage #2: N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole In ethyl acetate at 55 - 60℃;
Stage #3: With phosphonic Acid In ethyl acetate for 1h;
95%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole
124750-51-2

N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole

N-[(2'-(1-triphenylmethyltetrazol-5-yl)biphenyl-4-yl)methyl]-(L)-valine benzyl ester phosphorous acid salt

N-[(2'-(1-triphenylmethyltetrazol-5-yl)biphenyl-4-yl)methyl]-(L)-valine benzyl ester phosphorous acid salt

Conditions
ConditionsYield
Stage #1: L-valine benzyl ester hydrochloride With sodium hydroxide In water pH=10 - 12;
Stage #2: N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole In ethyl acetate at 55 - 60℃;
Stage #3: With phosphorous acid In ethyl acetate for 1h;
95%
5-Chlorovaleroyl chloride
1575-61-7

5-Chlorovaleroyl chloride

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(S)-benzyl 2-(5-chloropentanamido)-3-methylbutanoate

(S)-benzyl 2-(5-chloropentanamido)-3-methylbutanoate

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane; water at 0 - 20℃;95%
With sodium hydrogencarbonate In dichloromethane; water95%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid
66863-43-2

(3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid

N-[(3S)-N-Boc-1,2,3,4-tetrahydro-β-carboline-3-carboxyl]-L-valine benzyl ester
945650-42-0

N-[(3S)-N-Boc-1,2,3,4-tetrahydro-β-carboline-3-carboxyl]-L-valine benzyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0 - 20℃; for 18h;94%
With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0 - 20℃; for 18h; pH=8 - 9;94%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

benzyl (fluorosulfuryl)-L-valinate

benzyl (fluorosulfuryl)-L-valinate

Conditions
ConditionsYield
Stage #1: L-valine benzyl ester hydrochloride With sodium carbonate In acetonitrile at 20℃; for 16h;
Stage #2: With 1-(fluorosulfuryl)-2,3-dimethyl-1H-imidazol-3-ium trifluoromethanesulfonate at 20℃; for 1h;
94%
(C5H9O2)(NHCHCO)2(C4H9)(C3H7)(NHC4H4NO3)
663621-54-3

(C5H9O2)(NHCHCO)2(C4H9)(C3H7)(NHC4H4NO3)

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(C5H9O2)(NHCH(C4H9)CO)(NHCH(C3H7))(NHCONHCH(C3H7)COOC7H7)

(C5H9O2)(NHCH(C4H9)CO)(NHCH(C3H7))(NHCONHCH(C3H7)COOC7H7)

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile93%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

benzyl N-triflyl-L-valinate

benzyl N-triflyl-L-valinate

Conditions
ConditionsYield
Stage #1: L-valine benzyl ester hydrochloride With triethylamine In dichloromethane at -78℃; for 0.0833333h; Schlenk technique;
Stage #2: trifluoromethylsulfonic anhydride In dichloromethane at -78℃; Schlenk technique;
93%
2-(3-(trifluoromethoxy)phenyl)acetic acid
203302-97-0

2-(3-(trifluoromethoxy)phenyl)acetic acid

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(S)-3-methyl-2-[2-(3-trifluoromethoxyphenyl)acetylamino]butyric acid benzyl ester

(S)-3-methyl-2-[2-(3-trifluoromethoxyphenyl)acetylamino]butyric acid benzyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide Cooling with ice;92.5%
formic acid cyanomethyl ester
150760-95-5

formic acid cyanomethyl ester

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

N-Formyl-L-valine benzyl ester
71738-67-5

N-Formyl-L-valine benzyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane for 12h; Ambient temperature;92%
L-N-Boc-Ala
15761-38-3

L-N-Boc-Ala

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

Boc-L-Ala-L-Val-OBzl
116798-35-7

Boc-L-Ala-L-Val-OBzl

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0 - 20℃;92%
2,3-dihydro-1,4-benzodioxin-6-carboxylic acid
4442-54-0

2,3-dihydro-1,4-benzodioxin-6-carboxylic acid

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(S)-benzyl 2-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-3-methylbutanoate
1391931-81-9

(S)-benzyl 2-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-3-methylbutanoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 25℃; for 18h; Inert atmosphere;92%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(E)-3-(4,4,4-trifluorobut-2-enoyl)oxazolidin-2-one
243121-09-7

(E)-3-(4,4,4-trifluorobut-2-enoyl)oxazolidin-2-one

(S)-3-Methyl-2-[3-oxo-3-(2-oxo-oxazolidin-3-yl)-1-trifluoromethyl-propylamino]-butyric acid benzyl ester

(S)-3-Methyl-2-[3-oxo-3-(2-oxo-oxazolidin-3-yl)-1-trifluoromethyl-propylamino]-butyric acid benzyl ester

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 68h; Addition;90%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

L-valine benzyl ester
21760-98-5

L-valine benzyl ester

Conditions
ConditionsYield
With triethylamine In chloroform at 0 - 5℃; for 0.166667h;90%
With sodium hydrogencarbonate In water pH=8 - 9;
With sodium carbonate In water
C24H22ClN2OP

C24H22ClN2OP

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

C36H38N3O3P

C36H38N3O3P

Conditions
ConditionsYield
With triethylamine In dichloromethane at 90℃; for 12h; Molecular sieve; Sealed tube; Green chemistry;90%
N-(9-fluorenylmethyloxycarbonyl)-S-(4-O-acetyl-2,3,6-trideoxy-α-L-erythrohex-2-enopyranosyl)-L-cysteine

N-(9-fluorenylmethyloxycarbonyl)-S-(4-O-acetyl-2,3,6-trideoxy-α-L-erythrohex-2-enopyranosyl)-L-cysteine

L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

N-(9-fluorenylmethyloxycarbonyl)-S-(4-O-acetyl-2,3,6-trideoxy-α-L-erythro-hex-2-enopyranosyl)-L-cysteinyl-L-valine benzyl ester

N-(9-fluorenylmethyloxycarbonyl)-S-(4-O-acetyl-2,3,6-trideoxy-α-L-erythro-hex-2-enopyranosyl)-L-cysteinyl-L-valine benzyl ester

Conditions
ConditionsYield
With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine In dichloromethane at 20℃; for 24h;90%
L-valine benzyl ester hydrochloride
2462-34-2

L-valine benzyl ester hydrochloride

(2-trifluoromethyl-acryloylamino)-acetic acid benzyl ester
587885-53-8

(2-trifluoromethyl-acryloylamino)-acetic acid benzyl ester

(S)-2-[2-(Benzyloxycarbonylmethyl-carbamoyl)-3,3,3-trifluoro-propylamino]-3-methyl-butyric acid benzyl ester

(S)-2-[2-(Benzyloxycarbonylmethyl-carbamoyl)-3,3,3-trifluoro-propylamino]-3-methyl-butyric acid benzyl ester

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In tetrachloromethane at 20℃; for 2h; aza-Michael addition;89%

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