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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:yellowis to white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

5-Amino-1H-benzoimidazole-2-thiol

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Mercapto-5-Amino Benzimidazole supplier in China

Cas:2818-66-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Mercapto-5-Amino Benzimidazole

Cas:2818-66-8

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 2818-66-8 with best quality

Cas:2818-66-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2H-Benzimidazole-2-thione,5-amino-1,3-dihydro- 2818-66-8

Cas:2818-66-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

2H-Benzimidazole-2-thione,5-amino-1,3-dihydro-/ LIDE PHARMA- Factory supply / Best price

Cas:2818-66-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Amino-2-benzimidazolethiol CAS:2818-66-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

5-Amino-2-benzimidazolethiol CAS:2818-66-8

Cas:2818-66-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2H-Benzimidazole-2-thione,5-amino-1,3-dihydro-

Cas:2818-66-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2H-Benzimidazole-2-thione,5-amino-1,3-dihydro-

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Amino-2-Benzimidazolethiol

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Amino-1H-benzimidazole-2-thiol

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Mercapto-5-Amino Benzimidazole

Cas:2818-66-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystal powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermed

2H-Benzimidazole-2-thione,5-amino-1,3-dihydro-

Cas:2818-66-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 5-Amino-2-benzimidazolethiol

Cas:2818-66-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

5-Amino-2-benzimidazolethiol

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Other

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity 2-Mercapto-5-Amino Benzimidazole 2818-66-8

Cas:2818-66-8

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-AMino-2-MercaptobenziMidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

2-Mercapto-5-Amino Benzimidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Sinotech Import&Export Corporation

Boiling point 393.8 °C at 760 mmHg Melting point 67 °C Density 1.094 g/cm3 Storage

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2H-Benzimidazole-2-thione,5-amino-1,3-dihydro-

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

2-mercapto-5-amino benzimidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

5-Amino-2-benzimidazolethiol

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

5-Amino-2-benzimidazolethiol CAS No.2818-66-8

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

5-Amino-2-mercaptobenzimidazole

Cas:2818-66-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

5-nitro-2-mercaptobenzimidazole
6325-91-3

5-nitro-2-mercaptobenzimidazole

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

Conditions
ConditionsYield
With hydrogenchloride; iron In ethanol; water80%
With hydrogenchloride; iron In ethanol; water80%
Stage #1: 5-nitro-2-mercaptobenzimidazole With hydrogenchloride; zinc In methanol; water at 20℃; for 0.5 - 2h;
Stage #2: With potassium carbonate In methanol; water for 1h; pH=9 - 10; Product distribution / selectivity; Heating / reflux;
65%
hexakis[(4-formyl-2-methoxy)phenoxy]cyclotriphosphazene
1146953-82-3

hexakis[(4-formyl-2-methoxy)phenoxy]cyclotriphosphazene

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

hexa[2-methoxy-4-(2-mercapto-benzimidazol-5-yl-iminomethyl)phenoxy]cyclotriphosphazene

hexa[2-methoxy-4-(2-mercapto-benzimidazol-5-yl-iminomethyl)phenoxy]cyclotriphosphazene

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 24h;100%
4-Trifluoromethylbenzaldehyde
455-19-6

4-Trifluoromethylbenzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2-(4-(trifluromethyl)phenyl)thiazolidin-4-one

3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2-(4-(trifluromethyl)phenyl)thiazolidin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reagent/catalyst; Solvent; Reflux;98%
2-(naphthalene-2-sulfonyloxy)-benzaldehyde

2-(naphthalene-2-sulfonyloxy)-benzaldehyde

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

2-[(2-sulfanyl-1H-benzo[d]imidazol-5-yl)iminomethyl]phenyl naphthalene-2-sulfonate

2-[(2-sulfanyl-1H-benzo[d]imidazol-5-yl)iminomethyl]phenyl naphthalene-2-sulfonate

Conditions
ConditionsYield
With acetic acid for 2h; Reflux;98%
mercaptoacetic acid
68-11-1

mercaptoacetic acid

4-cyanobenzaldehyde
105-07-7

4-cyanobenzaldehyde

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

4-(3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-4-oxothiazolidin-2-yl)benzonitrile

4-(3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-4-oxothiazolidin-2-yl)benzonitrile

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reflux;96%
mercaptoacetic acid
68-11-1

mercaptoacetic acid

2-nitro-benzaldehyde
552-89-6

2-nitro-benzaldehyde

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2-(2-nitrophenyl)thiazolidin-4-one

3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2-(2-nitrophenyl)thiazolidin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reflux;93%
5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

5-phenyl-1H-pyrazole-3-carboxylic acid
5071-61-4

5-phenyl-1H-pyrazole-3-carboxylic acid

N-(2-mercaptobenzimidazol-5-yl)-5-phenyl-3-pyrazole carboxamide

N-(2-mercaptobenzimidazol-5-yl)-5-phenyl-3-pyrazole carboxamide

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine In N,N-dimethyl-formamide for 4 - 10h; Reflux; Inert atmosphere;92%
3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2-(3-nitrophenyl)thiazolidin-4-one

3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2-(3-nitrophenyl)thiazolidin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reflux;91%
hexa(4-bromo-2-formylphenoxy)cyclotriphosphazene
1443380-69-5

hexa(4-bromo-2-formylphenoxy)cyclotriphosphazene

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

hexa[4-bromo-2-(2-mercapto-benzimidazol-5-yliminomethyl)phenoxy]cyclotriphosphazene

hexa[4-bromo-2-(2-mercapto-benzimidazol-5-yliminomethyl)phenoxy]cyclotriphosphazene

Conditions
ConditionsYield
With formic acid In tetrahydrofuran at 20℃; for 24h;90.2%
isovanillin
621-59-0

isovanillin

tetrahydrofuran-2,4-dione
4971-56-6

tetrahydrofuran-2,4-dione

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

10-(3-hydroxy-4-methoxyphenyl)-2-sulfanyl-6,7,9,10-tetrahydro-1H-furo[3,4-b]imidazo[4,5-f]quinolin-9-one

10-(3-hydroxy-4-methoxyphenyl)-2-sulfanyl-6,7,9,10-tetrahydro-1H-furo[3,4-b]imidazo[4,5-f]quinolin-9-one

Conditions
ConditionsYield
In ethanol for 1h; Reflux;90%
cis,trans-2,5-dimethoxytetrahydrofuran
696-59-3

cis,trans-2,5-dimethoxytetrahydrofuran

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
172152-53-3

5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol

Conditions
ConditionsYield
With sodium acetate In acetic acid at 50℃; for 4h; Product distribution / selectivity;85%
Stage #1: cis,trans-2,5-dimethoxytetrahydrofuran; 5-amino-2-mercaptobenzimidazole With acetic acid at 50℃; for 4h;
Stage #2: With sodium hydroxide In tetrahydrofuran; water at 5℃; Product distribution / selectivity;
85%
With acetic acid
hexa(4-chloro-2-formylphenoxy)cyclotriphosphazene
1443380-71-9

hexa(4-chloro-2-formylphenoxy)cyclotriphosphazene

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

hexa[4-chloro-2-(2-mercapto-benzimidazol-5-yliminomethyl)phenoxy]cyclotriphosphazene

hexa[4-chloro-2-(2-mercapto-benzimidazol-5-yliminomethyl)phenoxy]cyclotriphosphazene

Conditions
ConditionsYield
With formic acid In tetrahydrofuran at 20℃; for 24h;85%
2,6-dichlorobenzaldehyde
83-38-5

2,6-dichlorobenzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(2,6-dichlorophenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-(2,6-dichlorophenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: 2,6-dichlorobenzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reagent/catalyst; Solvent; Reflux;
83%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

2-mercapto-5-(tert-butoxycarbonyl)aminobenzimidazole

2-mercapto-5-(tert-butoxycarbonyl)aminobenzimidazole

Conditions
ConditionsYield
In tetrahydrofuran80%
In tetrahydrofuran80%
n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

A

2-mercapto-5-octanamidobenzimidazole
109869-57-0

2-mercapto-5-octanamidobenzimidazole

B

1,5-bis(5-octanamido-2-benzimidazoylthio)pentane

1,5-bis(5-octanamido-2-benzimidazoylthio)pentane

Conditions
ConditionsYield
In ISOPROPYLAMIDE; water; acetonitrileA 80%
B n/a
In ISOPROPYLAMIDE; water; acetonitrileA 80%
B n/a
piperonal
120-57-0

piperonal

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(1,3-benzodioxol-5-yl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepine-6-one

9-(1,3-benzodioxol-5-yl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepine-6-one

Conditions
ConditionsYield
Stage #1: piperonal; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
80%
2,6-dibromobenzaldehyde
67713-23-9

2,6-dibromobenzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(2,6-dibromophenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-(2,6-dibromophenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: 2,6-dibromobenzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
80%
3-Formylchromone
17422-74-1

3-Formylchromone

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

C17H13N3O2S

C17H13N3O2S

Conditions
ConditionsYield
In methanol Reflux;80%
4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(4-methylphenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-(4-methylphenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: 4-methyl-benzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
79%
mercaptoacetic acid
68-11-1

mercaptoacetic acid

4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-[4-(dimethylamino)phenyl]-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepine-6-one

9-[4-(dimethylamino)phenyl]-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepine-6-one

Conditions
ConditionsYield
Stage #1: 4-dimethylamino-benzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
79%
5-Bromo-1H-indole-2,3-dione
87-48-9

5-Bromo-1H-indole-2,3-dione

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

5-bromo-2-mercapto-5,7-dihydrospiro(imidazo[4',5':4,5']benzo[1,2-e][1,4]thiazepine-9,3'-indoline)-2',6(1H)-dione
1392322-70-1

5-bromo-2-mercapto-5,7-dihydrospiro(imidazo[4',5':4,5']benzo[1,2-e][1,4]thiazepine-9,3'-indoline)-2',6(1H)-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetonitrile at 80℃; for 24h;78%
ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

2-cyano-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)acetamide
1446427-77-5

2-cyano-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)acetamide

Conditions
ConditionsYield
In ethanol for 5h; Reflux;78%
benzaldehyde
100-52-7

benzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-phenyl-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-phenyl-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: benzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
78%
2-hydroxynaphthalene-1-carbaldehyde
708-06-5

2-hydroxynaphthalene-1-carbaldehyde

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

(E)-5-(((2-hydroxynaphthalen-1-yl)methylene)amino)-1H-benzo[d]imidazole-2(3H)-thione

(E)-5-(((2-hydroxynaphthalen-1-yl)methylene)amino)-1H-benzo[d]imidazole-2(3H)-thione

Conditions
ConditionsYield
In ethanol at 80℃; for 4h;78%
propionyl chloride
79-03-8

propionyl chloride

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

2-mercapto-5-propanamidobenzimidazole

2-mercapto-5-propanamidobenzimidazole

Conditions
ConditionsYield
With sodium hydroxide In ISOPROPYLAMIDE; water; acetonitrile77%
With sodium hydroxide In ISOPROPYLAMIDE; water; acetonitrile77%
mercaptoacetic acid
68-11-1

mercaptoacetic acid

2-methylphenyl aldehyde
529-20-4

2-methylphenyl aldehyde

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(2-methylphenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-(2-methylphenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: 2-methylphenyl aldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
77%
2-chloro-benzaldehyde
89-98-5

2-chloro-benzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(2-chlorophenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-(2-chlorophenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: 2-chloro-benzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
77%
indole-2,3-dione
91-56-5

indole-2,3-dione

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

2-mercapto-5,7-dihydrospiro(imidazo[4',5':4,5']benzo[1,2-e][1,4]thiazepine-9,3'-indoline)-2',6(1H)-dione
1392322-68-7

2-mercapto-5,7-dihydrospiro(imidazo[4',5':4,5']benzo[1,2-e][1,4]thiazepine-9,3'-indoline)-2',6(1H)-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetonitrile at 80℃; for 24h;75%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

9-(4-hydroxyphenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

9-(4-hydroxyphenyl)-2-sulfanyl-5,6,7,9-tetrahydro-1H-imidazo[4',5':4,5]benzo[e][1,4]thiazepin-6-one

Conditions
ConditionsYield
Stage #1: 4-hydroxy-benzaldehyde; 5-amino-2-mercaptobenzimidazole With toluene-4-sulfonic acid In toluene for 1h; Michael Addition; Reflux;
Stage #2: mercaptoacetic acid In toluene for 23h; Reflux;
75%
5-chloroindole 2,3-dione
17630-76-1

5-chloroindole 2,3-dione

mercaptoacetic acid
68-11-1

mercaptoacetic acid

5-amino-2-mercaptobenzimidazole
2818-66-8

5-amino-2-mercaptobenzimidazole

5-chloro-2-mercapto-5,7-dihydrospiro(imidazo[4',5':4,5']benzo[1,2-e][1,4]thiazepine-9,3'-indoline)-2',6(1H)-dione
1392322-69-8

5-chloro-2-mercapto-5,7-dihydrospiro(imidazo[4',5':4,5']benzo[1,2-e][1,4]thiazepine-9,3'-indoline)-2',6(1H)-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetonitrile at 80℃; for 24h;74%

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