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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appeara

3,4-Methylenedioxyphenylacetic Acid

Cas:2861-28-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

3,4-(Methylenedioxy)phenylacetic acid Manufacturer Factory CAS 2861-28-1 3,4-(Methylenedioxy)phenylacetic acid Manufacturer High quality Best price In stock factory CAS 2861-28-1 3,4-(Methylenedioxy)phenylacetic acid COA TDS price MSDS Name

3,4-(Methylenedioxy)phenylacetic acid Manufacturer Factory CAS 2861-28-1

Cas:2861-28-1

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3,4-(Methylenedioxy)phenylacetic acid CAS 2861-28-1

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 2861-28-1 with best price

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS:2861-28-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qual

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS:2861-28-1

Cas:2861-28-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS 2861-28-1

Cas:2861-28-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2861-28-1

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

2-(Benzo[d][1,3]dioxol-5-yl)acetic acid

Cas:2861-28-1

Min.Order:1 Gram

FOB Price: $36.0

Type:Trading Company

inquiry

Hebei Miheng Trading Co., Ltd.

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS 2861-28-1 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purc

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS 2861-28-1

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $50.0 / 70.0

Type:Trading Company

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(1,3-BENZODIOXOL-5-YL)ACETIC ACID

Cas:2861-28-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply benzo-1,3-dioxole-5-acetic acid

Cas:2861-28-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS 2861-28-1 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a st

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID CAS 2861-28-1

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID Synonyms: 5-(Carboxymethyl)-1,3-benzodioxole, 3,4-(Methylenedioxy)phenylacetic acid, Homopiperonylic acid;2-(2H-1,3-benzodioxol-5-yl)acetic acid;(Benzodioxol-5-yl)acetic Acid;2-(3,4-Methylenediox

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID 2861-28-1

Cas:2861-28-1

Min.Order:1 Kilogram

FOB Price: $230.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3,4-Methylenedioxyphenylacetic Acid

Cas:2861-28-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3,4-(METHYLENEDIOXY)PHENYLACETIC ACID Synonyms: (1,3-BENZODIOXOL-5-YL)ACETIC ACID;1,3-BENZODIOXOLE-5-ACETIC ACID;3,4-METHYLENDIOXYPHENYLACETIC ACID;3,4-(METHYLENEDIOXY)PHENYLACETIC ACID;ASISCHEM D13365;HOMOPIPERONYLIC ACID;TIMTEC-

3,4-(METHYLENEDIOXY)PHENYLACETIC ACID

Cas:2861-28-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Luyunjia Chemistry Xiamen Limited

Luyunjia Chemistry Xiamen Limited is a high-tech company specializing in R&D and manufacturing of photoinitiators monomers and oligomers, UV absorbers and pharmaceutical intermediates, and pharmaceutical intermediates of generic drug. and has a h

hight quality 3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Benzo-[1,3]-dioxole-yl-5-acetic acid cas no. 2861-28-1 98%

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

3,4-Methylenedioxyphenylacetic Acid

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

benzo-1,3-dioxole-5-acetic acid

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3,4-(Methylenedioxy)phenylacetic acid

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

3,4-(Methylenedioxy)phenylacetic acid cas 2861-28-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3,4-(Methylenedioxy)phenylacetic acid cas 2861-28-1

Cas:2861-28-1

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

3,4-methylenedioxyphenylacetonitrile
4439-02-5

3,4-methylenedioxyphenylacetonitrile

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol Hydrolysis;100%
benzo[1,3]dioxol-5-yl-acetic acid methyl ester
326-59-0

benzo[1,3]dioxol-5-yl-acetic acid methyl ester

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
Stage #1: benzo[1,3]dioxol-5-yl-acetic acid methyl ester With potassium hydroxide; water In methanol for 3h; Heating / reflux;
Stage #2: With hydrogenchloride In water pH=1;
99%
With 20percent aq. KOH In methanol for 3h; Heating;97%
3,4-(methylenedioxy)mandelic acid
27738-46-1

3,4-(methylenedioxy)mandelic acid

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With phosphonic Acid; methanesulfonic acid; sodium iodide In water at 40℃; for 48h; Inert atmosphere;98.4%
((E)-2-Benzo[1,3]dioxol-5-yl-1-dimethylamino-vinyl)-phosphonic acid diethyl ester
79054-42-5

((E)-2-Benzo[1,3]dioxol-5-yl-1-dimethylamino-vinyl)-phosphonic acid diethyl ester

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With hydrogen bromide at 100℃; for 0.166667h;95%
With water; hydrogen bromide at 100℃; for 0.166667h; Inert atmosphere;95%
C18H18O6

C18H18O6

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With sodium hypochlorite In acetonitrile at 20℃; for 3.5h;88%
(benzo[1,3]dioxol-5-yl)acetic acid ethyl ester
26664-86-8

(benzo[1,3]dioxol-5-yl)acetic acid ethyl ester

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran for 1.5h; Ambient temperature;87%
benzo[1,3]dioxol-5-yl-acetaldehyde
6543-34-6

benzo[1,3]dioxol-5-yl-acetaldehyde

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With jones reagent In acetone at 0℃;75%
carbon dioxide
124-38-9

carbon dioxide

1-(benzo[d][1,3]dioxol-5-yl)-N,N,N-trimethylmethanammonium iodide
112101-21-0

1-(benzo[d][1,3]dioxol-5-yl)-N,N,N-trimethylmethanammonium iodide

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide; N,N,N-trimethyl-(3',4'-methylenedioxyphenyl)methylammonium iodide With manganese; 2,9-dibutyl-4,7-dimethyl-1,10-phenanthroline; nickel(II) bromide diethylene glycol dimethyl ether In N,N-dimethyl-formamide at 90℃; under 760.051 Torr; for 72h; Schlenk technique;
Stage #2: With hydrogenchloride In water; N,N-dimethyl-formamide at 20℃; Schlenk technique; chemoselective reaction;
70%
1-allyl-3,4-methylenedioxybenzene
94-59-7

1-allyl-3,4-methylenedioxybenzene

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With potassium permanganate; tetradecyldimethylbenzylammonium chloride dihydrate; acetic acid In water; acetone; benzene for 72h; cooling;58%
With permanganate(VII) ion
Multi-step reaction with 2 steps
1: 1.) O3/O2, 2.) Zn, CH3COOH / 1.) CH3COOH, 0 deg C, 2.) 0 deg C, 2 h
2: 75 percent / Jones reagent / acetone / 0 °C
View Scheme
benzo[1,3]dioxol-5-yl-oxo-acetic acid
62396-98-9

benzo[1,3]dioxol-5-yl-oxo-acetic acid

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
Stage #1: benzo[1,3]dioxol-5-yl-oxo-acetic acid With hydrazine hydrate; potassium hydroxide at 0 - 110℃;
Stage #2: With hydrogenchloride at 0℃; pH=3 - 4;
45%
1-allyl-3,4-methylenedioxybenzene
94-59-7

1-allyl-3,4-methylenedioxybenzene

A

Piperonylic acid
94-53-1

Piperonylic acid

B

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With potassium permanganate; acetic acid
1-(1,3-benzodioxol-5-yl)-2-propanone
4676-39-5

1-(1,3-benzodioxol-5-yl)-2-propanone

A

Piperonylic acid
94-53-1

Piperonylic acid

B

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With sodium hypobromide
β-(benzo[1,3]dioxol-5-yl)pyruvic acid
884-18-4

β-(benzo[1,3]dioxol-5-yl)pyruvic acid

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With dihydrogen peroxide
((E)-2-Benzo[1,3]dioxol-5-yl-1-dimethylamino-vinyl)-phosphonic acid diethyl ester
79054-42-5

((E)-2-Benzo[1,3]dioxol-5-yl-1-dimethylamino-vinyl)-phosphonic acid diethyl ester

A

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

B

((E)-2-Benzo[1,3]dioxol-5-yl-1-hydroxy-vinyl)-phosphonic acid diethyl ester
79054-52-7

((E)-2-Benzo[1,3]dioxol-5-yl-1-hydroxy-vinyl)-phosphonic acid diethyl ester

C

(2-Benzo[1,3]dioxol-5-yl-acetyl)-phosphonic acid diethyl ester
79054-51-6

(2-Benzo[1,3]dioxol-5-yl-acetyl)-phosphonic acid diethyl ester

D

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

Conditions
ConditionsYield
With hydrogenchloride Product distribution; Ambient temperature; effect of concentration of HCl, of reaction time and temperature;
1-((Z)-2-Benzo[1,3]dioxol-5-yl-1-methoxy-vinyl)-1H-benzotriazole

1-((Z)-2-Benzo[1,3]dioxol-5-yl-1-methoxy-vinyl)-1H-benzotriazole

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With hydrogenchloride; zinc dibromide 1.) 1,4-dioxane, reflux, 1 h, 2.) 1,4-dioxane, reflux, 4 h; Yield given. Multistep reaction;
((E)-2-Benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-vinyl)-phosphonic acid diethyl ester

((E)-2-Benzo[1,3]dioxol-5-yl-1-piperidin-1-yl-vinyl)-phosphonic acid diethyl ester

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With hydrogenchloride for 0.5h; Heating; Yield given;
α'-nitro-α-<3.4-methylenedioxy-phenyl>-acetone

α'-nitro-α-<3.4-methylenedioxy-phenyl>-acetone

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With potassium permanganate
3.4-methylenedioxy-mandelic acid

3.4-methylenedioxy-mandelic acid

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With hydrogen bromide; acetic acid Behandeln des Reaktionsprodukts mit Zink und Salzsaeure;
(E)-3-(benzo[d][1,3]dioxol-5-yl)-2-cyanoacrylic acid
49711-55-9

(E)-3-(benzo[d][1,3]dioxol-5-yl)-2-cyanoacrylic acid

aqueous alkaline sodium hypochlorite solution

aqueous alkaline sodium hypochlorite solution

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

homopiperonylic acid nitrile

homopiperonylic acid nitrile

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With potassium hydroxide
1-(1,3-benzodioxol-5-yl)-2-propanone
4676-39-5

1-(1,3-benzodioxol-5-yl)-2-propanone

sodium hypobromite

sodium hypobromite

A

Piperonylic acid
94-53-1

Piperonylic acid

B

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

1-allyl-3,4-methylenedioxybenzene
94-59-7

1-allyl-3,4-methylenedioxybenzene

A

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

B

homopiperonal

homopiperonal

Conditions
ConditionsYield
With water; benzene bei der Ozonisation;
safrole glycol

safrole glycol

A

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

B

piperonal; piperonylic acid

piperonal; piperonylic acid

Conditions
ConditionsYield
With potassium permanganate
3,4-methylenedioxyphenylacetonitrile
4439-02-5

3,4-methylenedioxyphenylacetonitrile

A

(1,3-benzodioxol-5-ylmethyl)-amide
5661-47-2

(1,3-benzodioxol-5-ylmethyl)-amide

B

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
With potassium phosphate buffer; lyophilized Zea mays nitrilase ZmNIT2 EC 3.5.5.1 In water at 30℃; for 14h; pH=7.15; Title compound not separated from byproducts;
3,4-dihydroxyphenylacetate
102-32-9

3,4-dihydroxyphenylacetate

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 97 percent / conc. H2SO4 / 3 h / Heating
2: 55 percent / CsF / dimethylformamide / 3 h / Heating
3: 97 percent / 20percent aq. KOH / methanol / 3 h / Heating
View Scheme
Multi-step reaction with 3 steps
1.1: sulfuric acid / 3 h / Heating / reflux
2.1: cesium fluoride / N,N-dimethyl-formamide / 12 h / 90 °C
3.1: potassium hydroxide; water / methanol / 3 h / Heating / reflux
3.2: pH 1
View Scheme
2-(3,4-dihydroxyphenyl)acetic acid methyl ester
25379-88-8

2-(3,4-dihydroxyphenyl)acetic acid methyl ester

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 55 percent / CsF / dimethylformamide / 3 h / Heating
2: 97 percent / 20percent aq. KOH / methanol / 3 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: cesium fluoride / N,N-dimethyl-formamide / 12 h / 90 °C
2.1: potassium hydroxide; water / methanol / 3 h / Heating / reflux
2.2: pH 1
View Scheme
piperonal
120-57-0

piperonal

hydrogen sulfide remaining ammonium polysulfide

hydrogen sulfide remaining ammonium polysulfide

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) n-BuLi / 1.) THF, cyclohexane, -78 deg C, 1 h, 2.) THF, cyclohexane, a) -78 deg C, 1 h, b) from -78 deg C to RT, overnight
2: 1.) ZnBr2, 2.) aq. HCl / 1.) 1,4-dioxane, reflux, 1 h, 2.) 1,4-dioxane, reflux, 4 h
View Scheme
piperonal
120-57-0

piperonal

alkali

alkali

A

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

B

piperonal; piperonylic acid

piperonal; piperonylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 76 percent / NaOH / 3 h / 80 °C
2: 90 percent / copper(II) chloride dihydrate, HCl / 23 h / Heating
3: 87 percent / 1N NaOH / tetrahydrofuran / 1.5 h / Ambient temperature
View Scheme
2-(3,4-methylenedioxyphenyl)-1-(methylsulfinyl)-1-(methylthio)ethylene
35453-09-9

2-(3,4-methylenedioxyphenyl)-1-(methylsulfinyl)-1-(methylthio)ethylene

A

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

B

piperonal; piperonylic acid

piperonal; piperonylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / copper(II) chloride dihydrate, HCl / 23 h / Heating
2: 87 percent / 1N NaOH / tetrahydrofuran / 1.5 h / Ambient temperature
View Scheme
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

benzo[1,3]dioxol-5-yl-acetic acid methyl ester
326-59-0

benzo[1,3]dioxol-5-yl-acetic acid methyl ester

Conditions
ConditionsYield
In 1,4-dioxane; diethyl ether100%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

3,4-methylenedioxyphenylacetyl chloride
6845-81-4

3,4-methylenedioxyphenylacetyl chloride

Conditions
ConditionsYield
With oxalyl dichloride; N,N-dimethyl-formamide In toluene at 20℃; for 1h; Inert atmosphere;100%
With oxalyl dichloride In N,N-dimethyl-formamide; toluene at 20℃; for 1h;97%
With thionyl chloride In dichloromethane for 1h; Heating;
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

3,4-methylenedioxyphenethyl alcohol
6006-82-2

3,4-methylenedioxyphenethyl alcohol

Conditions
ConditionsYield
With dimethylsulfide borane complex In tetrahydrofuran at 25 - 30℃; for 1.25h;100%
With sodium tetrahydroborate; iodine100%
With borane tetrahydrofuran In tetrahydrofuran at 0 - 20℃; for 1h;98%
methanol
67-56-1

methanol

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

benzo[1,3]dioxol-5-yl-acetic acid methyl ester
326-59-0

benzo[1,3]dioxol-5-yl-acetic acid methyl ester

Conditions
ConditionsYield
With acetyl chloride In various solvent(s)100%
With oxalyl dichloride at 0℃;95%
With oxalyl dichloride at 0℃; for 0.5h;95%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

2-(3,4-dimethoxyphenyl)-ethylamine
120-20-7

2-(3,4-dimethoxyphenyl)-ethylamine

2-(benzo[d][1,3]dioxol-5-yl)-N-(3,4-dimethoxyphenethyl)acetamide
42971-27-7

2-(benzo[d][1,3]dioxol-5-yl)-N-(3,4-dimethoxyphenethyl)acetamide

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In tetrahydrofuran99%
Stage #1: 1,3-benzodioxole-5-acetic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 0 - 20℃; for 3.5h; Inert atmosphere;
Stage #2: 2-(3,4-dimethoxyphenyl)-ethylamine In tetrahydrofuran at 0 - 20℃; for 15.5h; Inert atmosphere;
80%
at 190 - 210℃; for 2h;73%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

(6-bromobenzo[1,3]dioxol-5-yl)acetic acid
5470-14-4

(6-bromobenzo[1,3]dioxol-5-yl)acetic acid

Conditions
ConditionsYield
With bromine In chloroform at 20℃; for 2h;99%
With bromine; acetic acid at 23℃; for 18h;97%
With N-Bromosuccinimide In dichloromethane at 20℃; for 2h;92%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

phenethylamine
64-04-0

phenethylamine

2-(2H-1,3-benzodioxol-5-yl)-N-(2-phenylethyl)acetamide
1427329-53-0

2-(2H-1,3-benzodioxol-5-yl)-N-(2-phenylethyl)acetamide

Conditions
ConditionsYield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;99%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

2-(2-(trifluoromethyl)phenyl)ethan-1-amine
774-18-5

2-(2-(trifluoromethyl)phenyl)ethan-1-amine

2-(2H-1,3-benzodioxol-5-yl)-N-{2-[2-(trifluoromethyl)phenyl]ethyl}acetamide
1427329-55-2

2-(2H-1,3-benzodioxol-5-yl)-N-{2-[2-(trifluoromethyl)phenyl]ethyl}acetamide

Conditions
ConditionsYield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;99%
BH3.THF

BH3.THF

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

3,4-methylenedioxyphenethyl alcohol
6006-82-2

3,4-methylenedioxyphenethyl alcohol

Conditions
ConditionsYield
In tetrahydrofuran; water98%
BH3THF

BH3THF

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

3,4-methylenedioxyphenethyl alcohol
6006-82-2

3,4-methylenedioxyphenethyl alcohol

Conditions
ConditionsYield
In tetrahydrofuran; water98%
In tetrahydrofuran; water98%
In tetrahydrofuran; water98%
BH3 THF

BH3 THF

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

3,4-methylenedioxyphenethyl alcohol
6006-82-2

3,4-methylenedioxyphenethyl alcohol

Conditions
ConditionsYield
In tetrahydrofuran; water98%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

4-Methoxyphenethylamine
55-81-2

4-Methoxyphenethylamine

2-(2H-1,3-benzodioxol-5-yl)-N-[2-(4-methoxyphenyl)ethyl]acetamide
1395084-65-7

2-(2H-1,3-benzodioxol-5-yl)-N-[2-(4-methoxyphenyl)ethyl]acetamide

Conditions
ConditionsYield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;98%
In 5,5-dimethyl-1,3-cyclohexadiene for 16h; Reflux; Inert atmosphere;80%
N-hydroxyphthalimide
524-38-9

N-hydroxyphthalimide

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

1,3-dioxoisoindolin-2-yl 2-(benzo[d][1,3]dioxol-5-yl)acetate

1,3-dioxoisoindolin-2-yl 2-(benzo[d][1,3]dioxol-5-yl)acetate

Conditions
ConditionsYield
With dmap; diisopropyl-carbodiimide In tetrahydrofuran at 20℃; Inert atmosphere;96%
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃; for 0.5h;83%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

N-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamine hydrochloride
80376-85-8

N-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamine hydrochloride

2-Benzo[1,3]dioxol-5-yl-N-methyl-N-(1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-acetamide

2-Benzo[1,3]dioxol-5-yl-N-methyl-N-(1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-acetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran for 18h; Ambient temperature;95%
ethyl bromide
74-96-4

ethyl bromide

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

(benzo[1,3]dioxol-5-yl)acetic acid ethyl ester
26664-86-8

(benzo[1,3]dioxol-5-yl)acetic acid ethyl ester

Conditions
ConditionsYield
With tetradecyl(trihexyl)phosphonium bistriflamide; N-ethyl-N,N-diisopropylamine at 30℃;95%
With tetradecyl(trihexyl)phosphonium bistriflimide; N-ethyl-N,N-diisopropylamine at 30℃; for 12h;95%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

isopropyl bromide
75-26-3

isopropyl bromide

isopropyl 2-(3,4-methylenedioxyphenyl)acetate

isopropyl 2-(3,4-methylenedioxyphenyl)acetate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 6h; Reflux;95%
With tetradecyl(trihexyl)phosphonium bistriflamide; N-ethyl-N,N-diisopropylamine at 40℃;93%
With tetradecyl(trihexyl)phosphonium bistriflimide; N-ethyl-N,N-diisopropylamine at 40℃; for 12h;93%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

pivaloyl chloride
3282-30-2

pivaloyl chloride

2-(3,4-Methylenedioxyphenyl)acetic pivalic anhydride
250261-64-4

2-(3,4-Methylenedioxyphenyl)acetic pivalic anhydride

Conditions
ConditionsYield
With triethylamine In diethyl ether at -78 - 0℃; for 1h; Substitution;94%
With triethylamine In diethyl ether at -78℃; for 1h;80%
With triethylamine In diethyl ether at -78 - 0℃; Acylation;
1-(3-phenylpropyl)piperazine
55455-92-0

1-(3-phenylpropyl)piperazine

1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

2-(3,4-methylenedioxy)phenyl-1-(4-(3-phenylpropyl)piperazin-1-yl)ethanone

2-(3,4-methylenedioxy)phenyl-1-(4-(3-phenylpropyl)piperazin-1-yl)ethanone

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;94%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

1-(3,4-dimethoxyphenyl)ethanone
1131-62-0

1-(3,4-dimethoxyphenyl)ethanone

benzo[1,3]dioxol-5-ylacetic acid 8-(3,4-dimethoxyphenyl)naphtho[2,3-d][1,3]dioxol-6-yl ester

benzo[1,3]dioxol-5-ylacetic acid 8-(3,4-dimethoxyphenyl)naphtho[2,3-d][1,3]dioxol-6-yl ester

Conditions
ConditionsYield
Stage #1: 1,3-benzodioxole-5-acetic acid With phosphoric acid; trifluoroacetic anhydride In acetonitrile at 25℃; for 0.5h;
Stage #2: 1-(3,4-dimethoxyphenyl)ethanone In acetonitrile at 25 - 80℃; for 20h;
93%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

5-Nitrosalicylaldehyde
97-51-8

5-Nitrosalicylaldehyde

3-(1,3-benzodioxol-5-yl)-6-nitro-2H-chromen-2-one
753470-29-0

3-(1,3-benzodioxol-5-yl)-6-nitro-2H-chromen-2-one

Conditions
ConditionsYield
With potassium acetate In acetic anhydride for 49h; Perkin-Oglialoro reaction; Heating;91%
With potassium acetate; acetic anhydride Heating;30%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

ammonium chloride

ammonium chloride

3,4-methylenedioxyphenethyl alcohol
6006-82-2

3,4-methylenedioxyphenethyl alcohol

Conditions
ConditionsYield
90%
90%
90%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

Benzoylformic acid
611-73-4

Benzoylformic acid

Conditions
ConditionsYield
With acetic anhydride for 3h; Heating / reflux;90%
With acetic anhydride Reflux;
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

(1,3-benzodioxol-5-ylmethyl)-amide
5661-47-2

(1,3-benzodioxol-5-ylmethyl)-amide

Conditions
ConditionsYield
With 1H-imidazole; urea In octane at 120℃; for 24h; Reagent/catalyst;90%
Stage #1: 1,3-benzodioxole-5-acetic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: With ammonia; ammonium chloride In methanol; dichloromethane; N,N-dimethyl-formamide for 2h;
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

para-methanesulfonylbenzaldehyde
5398-77-6

para-methanesulfonylbenzaldehyde

C17H14O6S
1430809-12-3

C17H14O6S

Conditions
ConditionsYield
With potassium acetate; acetic anhydride at 100℃; for 19h; Perkin Carboxylic Acid Synthesis;89%
1,3-benzodioxole-5-acetic acid
2861-28-1

1,3-benzodioxole-5-acetic acid

3,4,5-trimethoxy-benzaldehyde
86-81-7

3,4,5-trimethoxy-benzaldehyde

5-(3,4,5-trimethoxyphenyl)-5,8-dihydro[1,3]dioxolo[4,5-g]isochromen-7-one

5-(3,4,5-trimethoxyphenyl)-5,8-dihydro[1,3]dioxolo[4,5-g]isochromen-7-one

Conditions
ConditionsYield
Stage #1: 1,3-benzodioxole-5-acetic acid With trifluoroacetic anhydride In acetonitrile at 25℃; for 0.166667h; Green chemistry;
Stage #2: 3,4,5-trimethoxy-benzaldehyde In acetonitrile at 25℃; for 10h; Green chemistry;
88%
Stage #1: 1,3-benzodioxole-5-acetic acid With trifluoroacetic anhydride In acetonitrile at 25℃; for 0.166667h; Pictet-Spengler Synthesis;
Stage #2: 3,4,5-trimethoxy-benzaldehyde In acetonitrile at 25℃; for 10h; Pictet-Spengler Synthesis;

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