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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3,5-Diiodo-L-tyrosine Manufacturer/High quality/Best price/In stock

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White or off white crystalline powder Complies

High purity 3,5-Diiodo-L-tyrosine dihydrate with high quality cas:300-39-0

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $210.0 / 250.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,5-Diiodo-L-Tyrosine supplier in China

Cas:300-39-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high purity Appearance:Light yellow powder Storage:cold storage Package:meet the demand of customer Application:Biomedical reagents Transportation:by sea or by air Port:shanghai

3,5-DIIODO-L-TYROSINE

Cas:300-39-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3,5-diiodo-L-tyrosine

Cas:300-39-0

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,5-Diiodo-L-tyrosine

Cas:300-39-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

3,5-Diiodo-L-tyrosine dihydrate

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $0.96 / 1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3,5-Diiodo-L-tyrosine dihydrate 300-39-0

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM--3,5-Diiodo-L-tyrosine dihydrate

Cas:300-39-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 300-39-0 with best price

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: 3,5-Diiodo-L-tyrosine dihydrate CAS No.: 300-39-0 Molecular formula: C9H13I2NO5 Molecular weight: 469 Specification: G;KG Appearance: White to beige powder A

3,5-Diiodo-L-tyrosine dihydrate CAS:300-39-0

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3,5-Diiodo-L-tyrosine 300-39-0

Cas:300-39-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,5-Diiodo-L-tyrosine

Cas:300-39-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS 3,5-Diiodo-L-tyrosine dihydrate Basic information Product Name:

China Largest Manufacturer factory Supply 3,5-Diiodo-L-tyrosine dihydrate CAS 300-39-0

Cas:300-39-0

Min.Order:1000 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3,5-Diiodo-L-tyrosine

Cas:300-39-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,5-Diiodo-L-Tyrosine

Cas:300-39-0

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

3,5-diiodo-L-tyrosine

Cas:300-39-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,5-Diiodo-L-tyrosine dihydrate

Cas:300-39-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3,5-Diiodo-L-tyrosine dihydrate

Cas:300-39-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

300-39-0Appearance:White powder Storage:Store the shade Package:according to customers' requirements Application:Used in medical research. Pharmaceutical intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or C

L-3,5-Diiodo-tyrosine dihyate

Cas:300-39-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3,5-Diiodo-L-tyrosine dihydrate

Cas:300-39-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

3,5-Diiodo-L-tyrosine

Cas:300-39-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3,5-Diiodo-L-tyrosine dihydrate Synonyms: 3,5-Diiodo-L-tyrosine dihydrate, BR;Liothyronine EP Impurity B;3,5-Diiodo-4-hydroxy-β-phenylalanine;3,5-diiodo-l-tyrosin;3,5-Diiodotyrocine;3,5-Iodo-L-tyrosine;3,5-L-Diiodotyrosine;4-

3,5-Diiodo-L-tyrosine dihydrate 300-39-0 C9H9I2NO3

Cas:300-39-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: L-3,5-Diiodotyrosine CAS No.: 300-39-0 Molecule Formula:C9H9I2NO3 Molecule Weight:432.98 Purity: 98.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Lower Price L-3,5-Diiodotyrosine

Cas:300-39-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

High purity 3,5-Diiodo-L-tyrosine dihydrate with high quality cas:300-39-0

Cas:300-39-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

High purity 3,5-Diiodo-L-tyrosine dihydrate with high quality cas:300-39-0

Cas:300-39-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

High purity 3,5-Diiodo-L-tyrosine dihydrate with high quality cas:300-39-0

Cas:300-39-0

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

L-3,5-diiodotyrosine

Cas:300-39-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3,5-Diiodo-L-tyrosinedehydrate

Cas:300-39-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used in organic synthes

3,5-Diiodo-L-tyrosine

Cas:300-39-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

L-tyrosine
60-18-4

L-tyrosine

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

Conditions
ConditionsYield
With hydrogen iodide; acetic acid In dimethyl sulfoxide at 65℃; for 0.025h;84.63%
With iodine; ethylamine; sodium iodide In water for 0.666667h;73.5%
With ammonium hydroxide; iodine; potassium iodide
L-tyrosine
60-18-4

L-tyrosine

A

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

B

3-Iodo-L-tyrosine
70-78-0

3-Iodo-L-tyrosine

Conditions
ConditionsYield
With chloroamine-T; sodium iodide In water at 20℃; for 0.00277778h; Product distribution; other reaction time, pregenerated iodine, reaction in the presence of tryptophan and Nin-formyl-tryptophan;A 38.6%
B 32.6%
With iodide; dihydrogen peroxide; lactoperoxidase
3-Iodo-L-tyrosine
70-78-0

3-Iodo-L-tyrosine

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

Conditions
ConditionsYield
With iodine In water at 22℃; for 0.0833333h; potassim iodide/chloramine T in phosphate buffer instead of iodine; tritium isotope effect;
ammonia
7664-41-7

ammonia

iodine
7553-56-2

iodine

L-tyrosine
60-18-4

L-tyrosine

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

methanol
67-56-1

methanol

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

3,5-diiodo-L-thyrosine methyl ester
76318-50-8

3,5-diiodo-L-thyrosine methyl ester

Conditions
ConditionsYield
With sulfuryl dichloride at 0 - 20℃; Inert atmosphere;100%
With hydrogenchloride at 60℃; for 0.0416667h; Microwave irradiation;74.63%
With hydrogenchloride
With thionyl chloride
Boc-Val-ONSu
3392-12-9

Boc-Val-ONSu

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

(S)-2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid

(S)-2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; water at 20℃; Condensation;100%
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

copper(II) sulfate
7758-99-8

copper(II) sulfate

3,5-diiodo L-tyrosine copper complex

3,5-diiodo L-tyrosine copper complex

Conditions
ConditionsYield
Stage #1: 3,5-diiodo-l-tyrosine With sodium hydroxide In water for 1h;
Stage #2: copper(II) sulfate In water at 20 - 40℃; for 2h;
98%
methanol
67-56-1

methanol

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

3,5-diiodo-L-tyrosine methyl ester hydrochloride
151266-48-7

3,5-diiodo-L-tyrosine methyl ester hydrochloride

Conditions
ConditionsYield
Stage #1: methanol With thionyl chloride at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 3,5-diiodo-l-tyrosine at 20℃; for 16h;
98%
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

5,7-diiodo-1-oxaspiro[2.5]octa-4,7-dien-6-one

5,7-diiodo-1-oxaspiro[2.5]octa-4,7-dien-6-one

L-thyroxine
51-48-9

L-thyroxine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 24℃; for 16h; 0.2 M borate buffer, pH 8.0 (add. of 0.1 M NaOH);94%
copper(II) sulfate heptahydrate

copper(II) sulfate heptahydrate

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

{Cu(HOC6H2I2CH2CH(NH2)COO)2}
49553-16-4

{Cu(HOC6H2I2CH2CH(NH2)COO)2}

Conditions
ConditionsYield
With sodium hydroxide In water at 20℃; for 1h; Time;93.7%
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

acetic anhydride
108-24-7

acetic anhydride

N-acetyl-3,5-diiodo-L-tyrosine
1027-28-7

N-acetyl-3,5-diiodo-L-tyrosine

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 15℃;92%
With sodium hydroxide
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

C14H19I2NO4

C14H19I2NO4

Conditions
ConditionsYield
Stage #1: 3,5-diiodo-l-tyrosine With chloro-trimethyl-silane In 1,4-dioxane for 48h;
Stage #2: di-tert-butyl dicarbonate With sodium hydroxide In tetrahydrofuran; water at 0 - 20℃;
79%
formaldehyd
50-00-0

formaldehyd

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

(S)-7-hydroxy-6,8-diiodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride

(S)-7-hydroxy-6,8-diiodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,2-dimethoxyethane; water at 72℃; for 4h;72%
With hydrogenchloride In 1,2-dimethoxyethane; water at 72℃; Inert atmosphere;72%
With hydrogenchloride In 1,2-dimethoxyethane; water at 72℃; Inert atmosphere;72%
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

5-Iodo-1-oxa-spiro[2.5]octa-4,7-dien-6-one

5-Iodo-1-oxa-spiro[2.5]octa-4,7-dien-6-one

triiodothyronine
6893-02-3

triiodothyronine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 24℃; for 16h; 0.2 M borate buffer, pH 8.0 (add. of 0.1 M NaOH);70%
methanol
67-56-1

methanol

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3,5-diiodophenyl)propanoate
128781-80-6

(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3,5-diiodophenyl)propanoate

Conditions
ConditionsYield
Stage #1: methanol; 3,5-diiodo-l-tyrosine With thionyl chloride at 0℃; for 2h; Reflux;
Stage #2: With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃;
Stage #3: di-tert-butyl dicarbonate In dichloromethane at 20℃;
64%
With thionyl chloride; triethylamine 1.) -10 deg C - room temperature, 2.) CH2Cl2; Yield given. Multistep reaction;
cis-dichloridobis(1,10-phenanthroline)ruthenium(II)

cis-dichloridobis(1,10-phenanthroline)ruthenium(II)

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

sodium perchlorate

sodium perchlorate

Ru(N2C12H8)2(NH2CHCH2C6H2I2OHCOO)(1+)*NH2CHCH2C6H2I2OHCOO(1-)=Ru(N2C12H8)2(NH2CHCH2C6H2I2OHCOO)(NH2CHCH2C6H2I2OHCOO)

Ru(N2C12H8)2(NH2CHCH2C6H2I2OHCOO)(1+)*NH2CHCH2C6H2I2OHCOO(1-)=Ru(N2C12H8)2(NH2CHCH2C6H2I2OHCOO)(NH2CHCH2C6H2I2OHCOO)

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water Ru-complex was refluxed in mixt. of H2O and EtOH, to this soln. was added ligand followed by aq. NaOH, mixt. was heated at 70°C for 30 min, cooled to room temp., filtered, cooled to room temp., aq. soln. of NaClO4 was added; mixt. was stored in the dark for 48 h, solid was collected at the pump,washed with ice-cold H2O, dried in vac. over silica gel at room temp.; elem. anal.;64%
formaldehyd
50-00-0

formaldehyd

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

(S)-1,2,3,4-Tetrahydro-7-hydroxy-6,8-diiodoisoquinoline-3-carboxylic acid
142335-40-8

(S)-1,2,3,4-Tetrahydro-7-hydroxy-6,8-diiodoisoquinoline-3-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride In 1,2-dimethoxyethane; water at 72℃; for 18.5h;57%
With hydrogenchloride In 1,2-dimethoxyethane at 72℃; for 18.5h;55%
With hydrogenchloride In 1,2-dimethoxyethane at 72℃; for 18.5h;48%
indan-1,2,3-trione hydrate
485-47-2

indan-1,2,3-trione hydrate

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

1,2,3-triphenylcyclopropene
16510-49-9

1,2,3-triphenylcyclopropene

(±)-(1R,4R,5S,6R)-4-(4-hydroxy-3,5-diiodobenzyl)-1,5,6-triphenyl-3-azaspiro[bicyclo[3.1.0]hexane-2,2'-indene]-1',3'-dione

(±)-(1R,4R,5S,6R)-4-(4-hydroxy-3,5-diiodobenzyl)-1,5,6-triphenyl-3-azaspiro[bicyclo[3.1.0]hexane-2,2'-indene]-1',3'-dione

Conditions
ConditionsYield
In methanol; water for 10h; Reflux; diastereoselective reaction;57%
N-(tert-butyloxycarbonyl) azide
1070-19-5

N-(tert-butyloxycarbonyl) azide

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

(tert-butoxycarbonyl)-3,5-diiodotyrosine
62129-53-7

(tert-butoxycarbonyl)-3,5-diiodotyrosine

Conditions
ConditionsYield
In dimethyl sulfoxide Ambient temperature;50%
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

methyl iodide
74-88-4

methyl iodide

A

(E)-methyl 3-(3,5-diiodo-4-methoxyphenyl)acrylate

(E)-methyl 3-(3,5-diiodo-4-methoxyphenyl)acrylate

B

L-3,5-diiodo-O-methyltyrosine methyl ester

L-3,5-diiodo-O-methyltyrosine methyl ester

C

L-3,5-diiodo-O,N,N-trimethyltyrosine methyl ester

L-3,5-diiodo-O,N,N-trimethyltyrosine methyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone for 24h; Heating;A 50%
B 20%
C 20%
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

indole-2,3-dione
91-56-5

indole-2,3-dione

1,2,3-triphenylcyclopropene
16510-49-9

1,2,3-triphenylcyclopropene

(±)-(1R,2R,4R,5S,6R)-4-(4-hydroxy-3,5-diiodobenzyl)-1,5,6-triphenyl-3-azaspiro[bicyclo[3.1.0]hexane-2,3′-indolin]-2′-one

(±)-(1R,2R,4R,5S,6R)-4-(4-hydroxy-3,5-diiodobenzyl)-1,5,6-triphenyl-3-azaspiro[bicyclo[3.1.0]hexane-2,3′-indolin]-2′-one

Conditions
ConditionsYield
In methanol; water Reflux; diastereoselective reaction;42%
1-oxaspiro[2.5]octa-4,7-dien-6-one
54337-43-8

1-oxaspiro[2.5]octa-4,7-dien-6-one

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 24℃; for 16h; 0.2 M borate buffer, pH 8.0 (add. of 0.1 M NaOH);15%
ethanol
64-17-5

ethanol

3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

3,5-diiodo-L-tyrosine ethyl ester
35591-33-4

3,5-diiodo-L-tyrosine ethyl ester

Conditions
ConditionsYield
With hydrogenchloride
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

L-thyroxine
51-48-9

L-thyroxine

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; butan-1-ol
Multi-step reaction with 4 steps
1.1: sodium hydroxide / water / 1 h
1.2: 2 h / 20 - 40 °C
2.1: diisopropylamine / water; butan-1-ol / 2 h / 20 - 90 °C
2.2: 2 h / 20 - 30 °C
3.1: acetic acid; hydrogen iodide / 5 h / 100 °C
4.1: methylamine / methanol / 25 - 30 °C
4.2: -8 - 0 °C
4.3: 15 - 20 °C
View Scheme
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

4-(4-hydroxy-3,5-diiodo-benzyl)-2-methyl-4H-oxazol-5-one

4-(4-hydroxy-3,5-diiodo-benzyl)-2-methyl-4H-oxazol-5-one

Conditions
ConditionsYield
With acetic anhydride
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

acetic anhydride
108-24-7

acetic anhydride

3.5-diiodo-N.O-diacetyl-L-tyrosine
96679-34-4

3.5-diiodo-N.O-diacetyl-L-tyrosine

Conditions
ConditionsYield
With sodium hydroxide
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

acetic anhydride
108-24-7

acetic anhydride

N-[1-acetyl-2-(4-hydroxy-3,5-diiodo-phenyl)-ethyl]-acetamide

N-[1-acetyl-2-(4-hydroxy-3,5-diiodo-phenyl)-ethyl]-acetamide

Conditions
ConditionsYield
With sodium carbonate
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

2,4-Dinitrofluorobenzene
70-34-8

2,4-Dinitrofluorobenzene

N-(2,4-dinitro-phenyl)-3,5-diiodo-L-tyrosine
100961-33-9

N-(2,4-dinitro-phenyl)-3,5-diiodo-L-tyrosine

Conditions
ConditionsYield
With diethyl ether; sodium hydrogencarbonate
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

2,4-Dinitrofluorobenzene
70-34-8

2,4-Dinitrofluorobenzene

O-(2,4-dinitro-phenyl)-3,5-diiodo-L-tyrosine

O-(2,4-dinitro-phenyl)-3,5-diiodo-L-tyrosine

Conditions
ConditionsYield
With sodium hydrogencarbonate
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

2,4-Dinitrofluorobenzene
70-34-8

2,4-Dinitrofluorobenzene

N,O-bis-(2,4-dinitro-phenyl)-3,5-diiodo-L-tyrosine
7093-57-4

N,O-bis-(2,4-dinitro-phenyl)-3,5-diiodo-L-tyrosine

Conditions
ConditionsYield
With diethyl ether; sodium hydrogencarbonate
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

chloroacetyl chloride
79-04-9

chloroacetyl chloride

N-chloroacetyl-3,5-diiodo-L-tyrosine
91348-81-1

N-chloroacetyl-3,5-diiodo-L-tyrosine

Conditions
ConditionsYield
With ethyl acetate
3,5-diiodo-l-tyrosine
300-39-0

3,5-diiodo-l-tyrosine

butan-1-ol
71-36-3

butan-1-ol

3,5-diiodo-L-tyrosine butyl ester

3,5-diiodo-L-tyrosine butyl ester

Conditions
ConditionsYield
With hydrogenchloride

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