DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:303-49-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryJinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu
Cas:303-49-1
Min.Order:1 Gram
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Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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Cas:303-49-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryFirst-class antidepressant Clomipramine 303-49-1 on hot selling 1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appea
Cas:303-49-1
Min.Order:100 Gram
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Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryClomipramine CAS: 303-49-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates
Cas:303-49-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Clomipramine cas 303-49-1 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control syste
Cas:303-49-1
Min.Order:1 Kilogram
FOB Price: $10.0 / 50.0
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Min.Order:0
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:303-49-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryEstablished in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o
Cas:303-49-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:303-49-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Product Name: Clomipramine Synonyms: g34586;Hydiphen;Monochlorimipramine;RARECHEM AX KI 5027;CLOMIPRAMINE HYDROCLORIDE;AURORA KA-7606;CHLORIMIPRAMINE;CHLORIMIPRAMINE HYDROCHLORIDE CAS: 303-49-1 MF: C19H23ClN2 MW:
Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:303-49-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
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Cas:303-49-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryhigh quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:303-49-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai
clomipramine N-oxide
Clomipramine
Conditions | Yield |
---|---|
With sodium tetrahydroborate In water at 50 - 60℃; chemoselective reaction; | 82% |
3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepine
N,N-dimethyl-3-bromopropylamine
Clomipramine
Conditions | Yield |
---|---|
Stage #1: 3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepine With sodium hydride In tetrahydrofuran at 110℃; for 2h; Glovebox; Inert atmosphere; Schlenk technique; Stage #2: N,N-dimethyl-3-bromopropylamine In tetrahydrofuran at 110℃; for 22h; Glovebox; Inert atmosphere; Schlenk technique; | 66% |
3-chloro-5H-dibenzo[b,f]azepine
3-(Dimethylamino)propyl chloride
Clomipramine
Conditions | Yield |
---|---|
Stage #1: 3-chloro-5H-dibenzo[b,f]azepine With methanol; magnesium at 50℃; for 1.5h; Stage #2: 3-(Dimethylamino)propyl chloride |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: caesium carbonate; triphenylphosphine; palladium diacetate; potassium iodide / N,N-dimethyl-formamide / 46 h / 105 °C / Schlenk technique; Inert atmosphere 2: N,N-dimethyl-formamide / 24 h / 130 °C / Schlenk technique; Inert atmosphere 3: magnesium; methanol / 1.5 h / 50 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: caesium carbonate; triphenylphosphine; palladium diacetate; potassium iodide / N,N-dimethyl-formamide / 46 h / 105 °C / Schlenk technique; Inert atmosphere 2: N,N-dimethyl-formamide / 24 h / 130 °C / Schlenk technique; Inert atmosphere 3: magnesium; methanol / 1.5 h / 50 °C View Scheme |
3-chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenzo(6,5)azepine
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: potassium hydroxide; triethyl borane / tetrahydrofuran / 24 h / 100 °C / Inert atmosphere; Schlenk technique; Sealed tube 2.1: sodium hydroxide; water / tetrahydrofuran / 1 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube 3.1: sodium hydride / tetrahydrofuran / 2 h / 110 °C / Glovebox; Inert atmosphere; Schlenk technique 3.2: 22 h / 110 °C / Glovebox; Inert atmosphere; Schlenk technique View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: sodium hydroxide; water / tetrahydrofuran / 1 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube 2.1: sodium hydride / tetrahydrofuran / 2 h / 110 °C / Glovebox; Inert atmosphere; Schlenk technique 2.2: 22 h / 110 °C / Glovebox; Inert atmosphere; Schlenk technique View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Stage #1: Clomipramine With hydrogenchloride In 1,4-dioxane; ethyl acetate Inert atmosphere; Stage #2: With 3,6-bis(dimethylamino)-9-(2,6-dimethylphenyl)-10-methylacridinium bromide; water-d2; lithium carbonate; triisopropylsilanethiol In 1-methyl-pyrrolidin-2-one at 20℃; for 24h; Inert atmosphere; Irradiation; regioselective reaction; | 98% |
Conditions | Yield |
---|---|
With C17H24N5Ru(1+)*F6P(1-); potassium acetate; potassium carbonate In 1-methyl-pyrrolidin-2-one at 35℃; for 24h; Inert atmosphere; | 97% |
Clomipramine
Conditions | Yield |
---|---|
Stage #1: Clomipramine With hydrogenchloride In 1,4-dioxane; ethyl acetate Inert atmosphere; Stage #2: With 9-(4-methoxyphenyl)-10-methylacridinium bromide; water-d2; lithium carbonate; triisopropylsilanethiol In 1-methyl-pyrrolidin-2-one at 20℃; for 24h; Inert atmosphere; Irradiation; regioselective reaction; | 88% |
Clomipramine
tris-iso-propylsilyl acetylene
Conditions | Yield |
---|---|
With chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate In acetonitrile at 85℃; for 7h; Sonogashira Cross-Coupling; | 87% |
Clomipramine
Conditions | Yield |
---|---|
Stage #1: Clomipramine With hydrogenchloride In 1,4-dioxane; ethyl acetate Inert atmosphere; Stage #2: With 9-(4-fluorophenyl)-10-methylacridinium bromide; water-d2; lithium carbonate; triisopropylsilanethiol In 1-methyl-pyrrolidin-2-one at 20℃; for 24h; Inert atmosphere; Irradiation; regioselective reaction; | 86% |
Clomipramine
Conditions | Yield |
---|---|
With hydrogen bromide; dimethyl sulfoxide In water; ethyl acetate at 60℃; for 5h; | 83% |
Clomipramine
Conditions | Yield |
---|---|
Stage #1: Clomipramine With hydrogenchloride In 1,4-dioxane; ethyl acetate Inert atmosphere; Stage #2: With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; water-d2; lithium carbonate; triisopropylsilanethiol In 1-methyl-pyrrolidin-2-one at 20℃; for 24h; Inert atmosphere; Irradiation; | 80% |
Clomipramine
3-(3-deuterio-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
Conditions | Yield |
---|---|
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; d8-isopropanol; potassium carbonate; bis(dibenzylideneacetone)-palladium(0) In acetonitrile at 100℃; for 2.5h; Inert atmosphere; Microwave irradiation; | 79% |
Clomipramine
Conditions | Yield |
---|---|
Stage #1: Clomipramine With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; water-d2; triisopropylsilanethiol In 1-methyl-pyrrolidin-2-one at 20℃; for 24h; Irradiation; Stage #2: With hydrogenchloride In 1-methyl-pyrrolidin-2-one Irradiation; | 76% |
Conditions | Yield |
---|---|
Stage #1: Clomipramine; ethyl 2-cyanoacetate With N-(2-methylnaphthalen-1-yl)-N’-(pyridin-2-ylmethyl)oxalamide; copper(I) bromide; sodium t-butanolate In isopropyl alcohol at 105℃; for 24h; Schlenk technique; Inert atmosphere; Stage #2: With water In isopropyl alcohol at 105℃; for 12h; Schlenk technique; Inert atmosphere; Cooling; | 72% |
Clomipramine
Conditions | Yield |
---|---|
With bis(1,5-cyclooctadiene)nickel(0); Dimethyl(phenyl)phosphine In toluene at 70℃; for 24h; Schlenk technique; | 69% |
Conditions | Yield |
---|---|
Stage #1: Clomipramine With chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate In acetonitrile for 0.416667h; Sonogashira Cross-Coupling; Glovebox; Stage #2: 3-(tetrahydropyran-2'-yloxy)propyne In acetonitrile at 80℃; for 20h; Sonogashira Cross-Coupling; Sealed tube; | 63% |
Clomipramine
triethyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane
Conditions | Yield |
---|---|
With 3,4,7,8-Tetramethyl-o-phenanthrolin; ferrous iodide; sodium t-butanolate In tetrahydrofuran at 120℃; for 12h; Schlenk technique; Glovebox; Inert atmosphere; | 54% |
Clomipramine
trimethyl(difluoromethyl)silane
Conditions | Yield |
---|---|
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; cesium fluoride; bis(dibenzylideneacetone)-palladium(0) In 1,4-dioxane at 100℃; for 16h; Reagent/catalyst; Glovebox; Sealed tube; | 48% |
Conditions | Yield |
---|---|
With oxygen In methanol; phosphate buffer at 25 - 28℃; pH=7.4; Product distribution; Further Variations:; Reagents; Photolysis; UV-irradiation; | A 15% B 15% C 40% D 20% |
Conditions | Yield |
---|---|
With oxygen; palladium on activated charcoal In methanol for 24h; Ambient temperature; |
Clomipramine
clomipramine N-oxide
Conditions | Yield |
---|---|
With dihydrogen peroxide In methanol for 168h; |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 40 °C / Inert atmosphere View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere 4.1: hydrogen; 10 wt% Pd(OH)2 on carbon / ethyl acetate View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 40 °C / Inert atmosphere 4.1: hydrogen; 10 wt% Pd(OH)2 on carbon / ethyl acetate View Scheme | |
Multi-step reaction with 4 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: hydrogen; 10 wt% Pd(OH)2 on carbon / ethyl acetate 4.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 40 °C / Inert atmosphere View Scheme |
Clomipramine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 40 °C / Inert atmosphere 4.1: hydrogen; 10 wt% Pd(OH)2 on carbon / ethyl acetate View Scheme | |
Multi-step reaction with 4 steps 1.1: chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2′,4′,6′-tri-1-propyl-1,1′-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); caesium carbonate / acetonitrile / 0.42 h / Glovebox 1.2: 20 h / 80 °C / Sealed tube 2.1: toluene-4-sulfonic acid / methanol / 2 h 3.1: hydrogen; 10 wt% Pd(OH)2 on carbon / ethyl acetate 4.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 40 °C / Inert atmosphere View Scheme |
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