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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

2-Methyl-4-nitrobenzoyl chloride

Cas:30459-70-2

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Methyl-4-nitrobenzoyl chloride

Cas:30459-70-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

2-Methyl-4-nitrobenzoyl chloride

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzoyl chloride, 2-methyl-4-nitro-

Cas:30459-70-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Benzoyl chloride, 2-methyl-4-nitro-

Cas:30459-70-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-methyl-4-nitrobenzoyl chloride cas no. 30459-70-2 98%

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

Benzoyl chloride, 2-methyl-4-nitro-

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Methyl-4-nitrobenzoyl chloride

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2-Methyl-4-nitrobenzoyl chloride

Cas:30459-70-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Reliable Pharmatech (Tianjin) Co., Ltd.

This product is manufactured in commercial scale, with Perfect quality and Competitive price Expert in pharmaceutical technology Professional service in technic, documentation, export, etc. Steady and continuous supply chain Reliable Pharma

2-methyl-4-nitrobenzoylchloride

Cas:30459-70-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Capot Chemical Co., Ltd.

At Capot,We can synthesize and purify your complex molecules from 100 gram to 10 tons.Appearance:Clear colorless to light yellow liquid Storage:Dry,Seal and Cool place Package:1G,5G,10G,25G,100G,250G,500G,1KG,5KG,10KG,25KG,50KG,100KG,150KG,200KG. App

2-Methyl-4-nitrobenzoyl chloride

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changzhou Ansciep Chemical Co.,Ltd.

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

30459-70-2

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Topbatt Chemical Co., Ltd.

Topbatt Chemical Co., Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutical Reference Standards and Stable Isotopes. Our Stable Isotopes produ

Tolvaptan Impurity 32

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Finetech Industry Limited

High Quality Best Price Storage:Store in dry, dark and ventilated place Application:Chemical Synthesis Intermediate

FT-0699585

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

2-methyl-4-oxo-2-Azetidineacetic acid

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shenzhen Sumshine Biotech Co., Ltd.

1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and

Tolvaptan Impurity 32

Cas:30459-70-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-methyl-4-nitrobenzoic acid
1975-51-5

2-methyl-4-nitrobenzoic acid

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

Conditions
ConditionsYield
With thionyl chloride
With thionyl chloride Heating;
With thionyl chloride Substitution;
methanol
67-56-1

methanol

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

methyl 2-methyl-4-nitrobenzoate
62621-09-4

methyl 2-methyl-4-nitrobenzoate

Conditions
ConditionsYield
In dichloromethane at 0℃; for 0.5h;100%
In dichloromethane at 0℃; for 0.5h;100%
2,2-dimethylpropionic acid 7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
863762-10-1

2,2-dimethylpropionic acid 7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
863762-20-3

2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 1h;98%
With triethylamine In dichloromethane at 0 - 20℃; for 1.25h;98%
2,2-dimethylpropionic acid 7-fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
863762-12-3

2,2-dimethylpropionic acid 7-fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

2,2-dimethylpropionic acid 7-fluoro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
863762-22-5

2,2-dimethylpropionic acid 7-fluoro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 1h;97%
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
160129-45-3

7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

1-(4-nitro-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
137982-91-3

1-(4-nitro-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine

Conditions
ConditionsYield
Stage #1: 7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one With magnesium hydroxide In acetonitrile at 10℃; for 0.5h;
Stage #2: 2-methyl-4-nitrobenzoyl chloride In acetonitrile for 5h;
95%
With sodium hydroxide In acetonitrile at 20℃; for 1h;73%
With triethylamine In dichloromethane at 20℃; for 2h; Acylation;32%
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine
313673-94-8

7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine

(7-chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)-2-methyl-4-nitrobenzamide
313673-96-0

(7-chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)-2-methyl-4-nitrobenzamide

Conditions
ConditionsYield
With pyridine In dichloromethane for 1h;91%
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

C13H16ClNO4

C13H16ClNO4

C21H21ClN2O7

C21H21ClN2O7

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 4h; Reagent/catalyst;88.7%
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

ethyl 4-(4-chlorophenylamino)butanoate

ethyl 4-(4-chlorophenylamino)butanoate

C20H21ClN2O5

C20H21ClN2O5

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 3h; Reagent/catalyst;88%
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

methyl 4-(2-amino-5-chlorophenyl)-4-oxobutyrate
80452-54-6

methyl 4-(2-amino-5-chlorophenyl)-4-oxobutyrate

C19H17ClN2O6
1417520-49-0

C19H17ClN2O6

Conditions
ConditionsYield
With pyridine In dichloromethane87%
L-glutamic acid diethyl ester
16450-41-2

L-glutamic acid diethyl ester

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

diethyl N-(2-methyl-4-nitrobenzoyl)-L-glutamate
80015-10-7

diethyl N-(2-methyl-4-nitrobenzoyl)-L-glutamate

Conditions
ConditionsYield
With pyridine In toluene at 0 - 25℃; for 1.5h;77%
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

4-methoxy-aniline
104-94-9

4-methoxy-aniline

N-(4-Methoxy-phenyl)-2-methyl-4-nitro-benzamide
101971-73-7

N-(4-Methoxy-phenyl)-2-methyl-4-nitro-benzamide

Conditions
ConditionsYield
In pyridine Heating;75%
L-glutamic acid
56-86-0

L-glutamic acid

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

N-(2-methyl-4-nitro-benzoyl)-L-glutamic acid

N-(2-methyl-4-nitro-benzoyl)-L-glutamic acid

Conditions
ConditionsYield
With sodium hydroxide
1-tert-butylamino-2,3-dihydroxypropane
22741-52-2

1-tert-butylamino-2,3-dihydroxypropane

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

2-Methyl-4-nitro-benzoic acid 3-tert-butylamino-2-hydroxy-propyl ester
90531-58-1

2-Methyl-4-nitro-benzoic acid 3-tert-butylamino-2-hydroxy-propyl ester

Conditions
ConditionsYield
With pyridine In toluene for 2h; Ambient temperature;
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

2-Diazo-1-(2-methyl-4-nitro-phenyl)-ethanone
50712-65-7

2-Diazo-1-(2-methyl-4-nitro-phenyl)-ethanone

Conditions
ConditionsYield
In diethyl ether
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine
22162-53-4

10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine

(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-(2-methyl-4-nitro-phenyl)-methanone
1027943-31-2

(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-(2-methyl-4-nitro-phenyl)-methanone

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

3,4,5,10,11,11a-hexahydro-1H-2-thia-4a,10-diazadibenzo[a,d]cycloheptene
705966-36-5

3,4,5,10,11,11a-hexahydro-1H-2-thia-4a,10-diazadibenzo[a,d]cycloheptene

(2-methyl-4-nitro-phenyl)-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cyclohepten-10-yl)-methanone

(2-methyl-4-nitro-phenyl)-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cyclohepten-10-yl)-methanone

Conditions
ConditionsYield
With triethylamine In dichloromethane
1H-pyrrolo[2,3-b]pyridin-5-amine
100960-07-4

1H-pyrrolo[2,3-b]pyridin-5-amine

2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

2-methyl-5-nitro-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)-benzamide
1012342-27-6

2-methyl-5-nitro-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)-benzamide

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; for 16h;
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

(4-amino-2-methyl-phenyl)-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cyclohepten-10-yl)-methanone

(4-amino-2-methyl-phenyl)-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cyclohepten-10-yl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Et3N / CH2Cl2
2: Zn; NH4Cl / methanol
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

biphenyl-2-carboxylic acid [3-methyl-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide

biphenyl-2-carboxylic acid [3-methyl-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Et3N / CH2Cl2
2: Zn; NH4Cl / methanol
3: Et3N / CH2Cl2
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

(4-amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-methanone

(4-amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / pyridine / CH2Cl2 / 1 h
2: 97 percent / SnCl2*2H2O / ethanol / 3 h / Heating
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

tolvaptan
150683-30-0

tolvaptan

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C
2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C
3: 53 percent / Et3N / CH2Cl2 / 1.5 h / 20 °C
4: 30 percent / NaBH4 / methanol / 1 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydrogencarbonate / dichloromethane; water / pH 7 - 8
2.1: tin(ll) chloride / methanol / 16 h / 20 °C
3.1: sodium hydrogencarbonate / dichloromethane / 0 - 5 °C / pH 7 - 8
4.1: sodium tetrahydroborate; methanol / 1 h / 20 °C
4.2: pH 6 - 7
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0
2.1: tin(IV) chloride / methanol / 16 h / 20 °C
3.1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0
4.1: sodium tetrahydroborate / methanol / 1 h / 20 °C
4.2: pH 6.0 - 7.0
View Scheme
Multi-step reaction with 4 steps
1.1: magnesium hydroxide / acetonitrile / 0.5 h / 10 °C
1.2: 5 h
2.1: methanol; tin(II) chloride dihdyrate / 23 h / 10 °C
3.1: magnesium hydroxide / dichloromethane; water / 0.5 h / 10 °C
3.2: 3 h
4.1: sodium tetrahydroborate; methanol / 1 h
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

1-(4-amino-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
137977-97-0

1-(4-amino-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C
2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / dichloromethane; water / pH 7 - 8
2: tin(ll) chloride / methanol / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0
2: tin(IV) chloride / methanol / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: magnesium hydroxide / acetonitrile / 0.5 h / 10 °C
1.2: 5 h
2.1: methanol; tin(II) chloride dihdyrate / 23 h / 10 °C
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

MOP-21826
137973-76-3

MOP-21826

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C
2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C
3: 53 percent / Et3N / CH2Cl2 / 1.5 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate / dichloromethane; water / pH 7 - 8
2: tin(ll) chloride / methanol / 16 h / 20 °C
3: sodium hydrogencarbonate / dichloromethane / 0 - 5 °C / pH 7 - 8
View Scheme
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0
2: tin(IV) chloride / methanol / 16 h / 20 °C
3: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0
View Scheme
Multi-step reaction with 3 steps
1.1: magnesium hydroxide / acetonitrile / 0.5 h / 10 °C
1.2: 5 h
2.1: methanol; tin(II) chloride dihdyrate / 23 h / 10 °C
3.1: magnesium hydroxide / dichloromethane; water / 0.5 h / 10 °C
3.2: 3 h
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

(4-Amino-2-methyl-phenyl)-(5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-methanone
211099-25-1

(4-Amino-2-methyl-phenyl)-(5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: H2 / Pd/C
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

N-[4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)-3-methyl phenyl]-5-fluoro-2-methylbenzamide

N-[4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)-3-methyl phenyl]-5-fluoro-2-methylbenzamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
2: H2 / Pd/C
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

diethyl N-(4-amino-2-methylbenzoyl)-L-glutamate
80014-85-3

diethyl N-(4-amino-2-methylbenzoyl)-L-glutamate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77 percent / pyridine / toluene / 1.5 h / 0 - 25 °C
2: 81 percent / H2 / 10percent Pd/C / ethanol / 760 Torr
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

diethyl N-<2-methyl-4-(prop-2-ynylamino)benzoyl>-L-glutamate
80014-86-4

diethyl N-<2-methyl-4-(prop-2-ynylamino)benzoyl>-L-glutamate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 77 percent / pyridine / toluene / 1.5 h / 0 - 25 °C
2: 81 percent / H2 / 10percent Pd/C / ethanol / 760 Torr
3: 37 percent / 2,6-lutidine / N,N-dimethyl-acetamide / 48 h / Ambient temperature
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

N-<2-methyl-4-prop-2-ynylamino>benzoyl>-L-glutamic acid
80014-99-9

N-<2-methyl-4-prop-2-ynylamino>benzoyl>-L-glutamic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 77 percent / pyridine / toluene / 1.5 h / 0 - 25 °C
2: 81 percent / H2 / 10percent Pd/C / ethanol / 760 Torr
3: 37 percent / 2,6-lutidine / N,N-dimethyl-acetamide / 48 h / Ambient temperature
4: 39 percent / CaCO3 / N,N-dimethyl-acetamide / 48 h / Ambient temperature
5: 38 percent / aq. NaOH / ethanol / 18 h / Ambient temperature
View Scheme
2-methyl-4-nitrobenzoyl chloride
30459-70-2

2-methyl-4-nitrobenzoyl chloride

diethyl N-<2-methyl-4-prop-2-ynylamino>benzoyl>-L-glutamate
80014-80-8

diethyl N-<2-methyl-4-prop-2-ynylamino>benzoyl>-L-glutamate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 77 percent / pyridine / toluene / 1.5 h / 0 - 25 °C
2: 81 percent / H2 / 10percent Pd/C / ethanol / 760 Torr
3: 37 percent / 2,6-lutidine / N,N-dimethyl-acetamide / 48 h / Ambient temperature
4: 39 percent / CaCO3 / N,N-dimethyl-acetamide / 48 h / Ambient temperature
View Scheme

Raw Materials

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