DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:160129-45-3
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inquiryTolvaptan[CAS:150683-30-0] 7-Chloro-1,2,3,4-Tetrahydrobenzo[b]Azepin-5-one[CAS:160129-45-3] Product: Tolvaptan Intermediate Chemical name: 7-Chloro-1,2,3,4-Tetrahydrobenzo[b]Azepin-5-one[CAS:160129-45-3] Batch No: 20101019-2 Man
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inquiryName:-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE CAS:160129-45-3 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage
Cas:160129-45-3
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inquiryTIANFUCHEM--160129-45-3--7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had es
Cas:160129-45-3
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiryTolvaptan intermediate Product Name: 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE Synonyms: 5H-1-Benzazepin-5-one,7-chloro-1,2,3,4-tetrahydro-;7-Chlorobenzo[b]azepan-5-one;7-chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one;7-Chloro-1,2,3,4
Cas:160129-45-3
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inquiryAppearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie
Cas:160129-45-3
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
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inquirySuperior quality, moderate price & quick delivery. Appearance:light yellow crystal Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermedia
Cas:160129-45-3
Min.Order:1 Gram
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Type:Trading Company
inquiryProduct name: 7-Chloro-1,2,3,4-Tetrahydrobenzo[b]azepin-5-one CAS No.: 160129-45-3 Molecule Formula:C10H10ClNO Molecule Weight:195.65 Purity: 99.0% Package: 25kg/drum Description:Yellow to lilght yellow powder Manufacture Standards:En
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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inquiryHunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
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inquiry7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
With hydrogenchloride In water at 50℃; for 3h; Reagent/catalyst; Temperature; | 90.3% |
7-chloro-1-(4-methylbenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Stage #1: 7-chloro-1-(4-methylbenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one With sulfuric acid In water at 0 - 10℃; for 2.5h; Stage #2: With sodium hydroxide In water | 89% |
With PPA at 80 - 100℃; for 1.5h; detosylation; | 81% |
With PPA at 100℃; |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
With formic acid at 150℃; for 3h; | 88.1% |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
With 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine In dichloromethane at 35℃; for 8h; Inert atmosphere; | 88% |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
With sulfuric acid at 50℃; for 2h; Temperature; | 84.6% |
Multi-step reaction with 2 steps 1: sulfuric acid / 2 h / 40 °C 2: hydrogenchloride / water / 3 h / 50 °C View Scheme |
4-chlorobenzenesulfonyl chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: 85 percent / pyridine / 20 °C 2.1: 94 percent / K2CO3 / dimethylformamide / 4 h / 120 °C 3.1: t-BuOK / toluene / 0.5 h / Heating 3.2: 60 percent / conc. HCl / acetic acid / 5 h / Heating 4.1: 81 percent / polyphosphoric acid / 1.5 h / 80 - 100 °C View Scheme |
5-chloro-2-nitrobenzoic acid
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: 100 percent / K2CO3 / acetone / 0.5 h / Heating 2.1: SnCl2*2H2O; conc. HCl / ethanol / 20 °C 3.1: 85 percent / pyridine / 20 °C 4.1: 94 percent / K2CO3 / dimethylformamide / 4 h / 120 °C 5.1: t-BuOK / toluene / 0.5 h / Heating 5.2: 60 percent / conc. HCl / acetic acid / 5 h / Heating 6.1: 81 percent / polyphosphoric acid / 1.5 h / 80 - 100 °C View Scheme |
methyl 5-chloro-2-nitrobenzoate
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: SnCl2*2H2O; conc. HCl / ethanol / 20 °C 2.1: 85 percent / pyridine / 20 °C 3.1: 94 percent / K2CO3 / dimethylformamide / 4 h / 120 °C 4.1: t-BuOK / toluene / 0.5 h / Heating 4.2: 60 percent / conc. HCl / acetic acid / 5 h / Heating 5.1: 81 percent / polyphosphoric acid / 1.5 h / 80 - 100 °C View Scheme |
N-p-toluenesulfonyl-5-chloro-anthranilic acid methyl ester
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: 94 percent / K2CO3 / dimethylformamide / 4 h / 120 °C 2.1: t-BuOK / toluene / 0.5 h / Heating 2.2: 60 percent / conc. HCl / acetic acid / 5 h / Heating 3.1: 81 percent / polyphosphoric acid / 1.5 h / 80 - 100 °C View Scheme |
methyl 5-chloro-2-[N-(3-ethoxycarbonyl)propyl-N-p-toluenesulfonyl]aminobenzoate
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: t-BuOK / toluene / 0.5 h / Heating 1.2: 60 percent / conc. HCl / acetic acid / 5 h / Heating 2.1: 81 percent / polyphosphoric acid / 1.5 h / 80 - 100 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Stage #1: ethyl 7-chloro-5-oxo-1-p-toluenesulfonyl-2,3,4,5-tetrahydro-1H-1-benzazepine-4-carboxylate With sulfuric acid In water at 75℃; for 2h; Stage #2: With sodium hydroxide In water pH=7.5 - 8; | |
Stage #1: ethyl 7-chloro-5-oxo-1-p-toluenesulfonyl-2,3,4,5-tetrahydro-1H-1-benzazepine-4-carboxylate With sulfuric acid; water at 75℃; for 2h; Stage #2: With sodium hydroxide In water at 20℃; pH=7.5 - 8.0; | 160 g |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 5,5-dimethyl-1,3-cyclohexadiene / 18 h / 175 °C / Sealed tube 2: sulfuric acid / water / 11 h / 90 °C 3: 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine / dichloromethane / 8 h / 35 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 4 steps 1.1: 5,5-dimethyl-1,3-cyclohexadiene / 18 h / 175 °C 2.1: sulfuric acid / water / 11 h / 90 °C 3.1: 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine / dichloromethane / 8 h / Inert atmosphere; Reflux 3.2: Cooling with ice 4.1: sodium hydrogencarbonate / water View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sulfuric acid / water / 11 h / 90 °C 2: 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine / dichloromethane / 8 h / 35 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1.1: sulfuric acid / water / 11 h / 90 °C 2.1: 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine / dichloromethane / 8 h / Inert atmosphere; Reflux 2.2: Cooling with ice 3.1: sodium hydrogencarbonate / water View Scheme |
5-chloro-2-fluorobenzaldehyde
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: potassium carbonate / water; acetonitrile / 72 h / Reflux 2: 5,5-dimethyl-1,3-cyclohexadiene / 18 h / 175 °C / Sealed tube 3: sulfuric acid / water / 11 h / 90 °C 4: 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine / dichloromethane / 8 h / 35 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 5 steps 1.1: potassium carbonate / acetonitrile; water / 60 h / Reflux 2.1: 5,5-dimethyl-1,3-cyclohexadiene / 18 h / 175 °C 3.1: sulfuric acid / water / 11 h / 90 °C 4.1: 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine / dichloromethane / 8 h / Inert atmosphere; Reflux 4.2: Cooling with ice 5.1: sodium hydrogencarbonate / water View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water | 745 mg |
2-methyl-4-nitrobenzoyl chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-nitro-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Stage #1: 7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one With magnesium hydroxide In acetonitrile at 10℃; for 0.5h; Stage #2: 2-methyl-4-nitrobenzoyl chloride In acetonitrile for 5h; | 95% |
With sodium hydroxide In acetonitrile at 20℃; for 1h; | 73% |
With triethylamine In dichloromethane at 20℃; for 2h; Acylation; | 32% |
carbon monoxide
2-bromo-5-nitrotoluene
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-nitro-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
With palladium diacetate; potassium carbonate; triphenylphosphine In water; N,N-dimethyl-formamide at 120℃; under 22502.3 Torr; for 8h; Temperature; Pressure; Autoclave; | 92.7% |
2-methoxy-4-nitrobenzoyl chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-1-(2-methoxy-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
With pyridine Acylation; | 92% |
Conditions | Yield |
---|---|
With triethylamine In ethanol for 15h; Reflux; | 90.4% |
3-chloro-4-nitro-benzoic acid chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-1-(3-chloro-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 2h; Acylation; | 89% |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-bromo-3-propanol
Conditions | Yield |
---|---|
With potassium hydrogencarbonate In N,N-dimethyl-formamide for 12h; Reflux; | 87.9% |
carbon monoxide
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
2-bromo-5-(2-methylbenzoylamino)toluene
MOP-21826
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; palladium diacetate In N,N-dimethyl-formamide at 125℃; for 3h; | 85% |
With 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium diacetate; triphenylphosphine In N,N-dimethyl-formamide at 20 - 125℃; for 3h; | 85% |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine
Conditions | Yield |
---|---|
With hydrazine hydrate; potassium hydroxide In 1,2-dimethoxyethane at 160℃; for 4h; | 77% |
carbon monoxide
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
2-bromo-5-(2-methylbenzoylamino)toluene
A
MOP-21826
B
2-methyl-4-(2-methylbenzoylamino)benzoic acid
Conditions | Yield |
---|---|
With cesium acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; palladium diacetate In N,N-dimethyl-formamide Heating; | A n/a B 75% |
4-nitro-benzoyl chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-1-(4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 2h; Acylation; | 57% |
2-chloro-4-nitrobenzoyl chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-1-(2-chloro-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 2h; Acylation; | 57% |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
Conditions | Yield |
---|---|
With C19H29N4Ru(1+)*C24H20B(1-); potassium hydroxide In isopropyl alcohol at 80℃; for 2h; Inert atmosphere; Schlenk technique; | 56% |
3-methoxy-4-nitrobenzoic acid chloride
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-1-(3-methoxy-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 2h; Acylation; | 31% |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
tolvaptan
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C 3: 53 percent / Et3N / CH2Cl2 / 1.5 h / 20 °C 4: 30 percent / NaBH4 / methanol / 1 h / 20 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydrogencarbonate / dichloromethane; water / pH 7 - 8 2.1: tin(ll) chloride / methanol / 16 h / 20 °C 3.1: sodium hydrogencarbonate / dichloromethane / 0 - 5 °C / pH 7 - 8 4.1: sodium tetrahydroborate; methanol / 1 h / 20 °C 4.2: pH 6 - 7 View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0 2.1: tin(IV) chloride / methanol / 16 h / 20 °C 3.1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0 4.1: sodium tetrahydroborate / methanol / 1 h / 20 °C 4.2: pH 6.0 - 7.0 View Scheme | |
Multi-step reaction with 4 steps 1: potassium carbonate; triphenylphosphine; palladium diacetate / N,N-dimethyl-formamide; water / 8 h / 120 °C / 22502.3 Torr / Autoclave 2: iron; ammonium chloride / water; methanol / 6 h / 35 - 40 °C 3: pyridine / dichloromethane / 2 h / 0 - 10 °C 4: sodium tetrahydroborate; methanol / 1 h / 15 - 30 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: magnesium hydroxide / acetonitrile / 0.5 h / 10 °C 1.2: 5 h 2.1: methanol; tin(II) chloride dihdyrate / 23 h / 10 °C 3.1: magnesium hydroxide / dichloromethane; water / 0.5 h / 10 °C 3.2: 3 h 4.1: sodium tetrahydroborate; methanol / 1 h View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-aminobenzoyl)-7-chloro-5-methoxy-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 57 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 99 percent / NaBH4 / methanol / 1 h / 20 °C 3: 71 percent / NaH / dimethylformamide / 1 h / 20 °C 4: 93 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-5-methoxy-1-(4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 57 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 99 percent / NaBH4 / methanol / 1 h / 20 °C 3: 71 percent / NaH / dimethylformamide / 1 h / 20 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-aminobenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 57 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 66 percent / conc. HCl; H2 / PtO2 / acetic acid / 760 Torr View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
7-chloro-5-hydroxy-1-(4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 57 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 99 percent / NaBH4 / methanol / 1 h / 20 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-amino-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: sodium hydrogencarbonate / dichloromethane; water / pH 7 - 8 2: tin(ll) chloride / methanol / 16 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: sodium hydrogencarbonate / water; dichloromethane / 0 - 5 °C / pH 7.0 - 8.0 2: tin(IV) chloride / methanol / 16 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate; triphenylphosphine; palladium diacetate / N,N-dimethyl-formamide; water / 8 h / 120 °C / 22502.3 Torr / Autoclave 2: iron; ammonium chloride / water; methanol / 6 h / 35 - 40 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: magnesium hydroxide / acetonitrile / 0.5 h / 10 °C 1.2: 5 h 2.1: methanol; tin(II) chloride dihdyrate / 23 h / 10 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-amino-3-chlorobenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 89 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 86 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-amino-2-methoxybenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 92 percent / pyridine 2: 89 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C View Scheme |
7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
1-(4-amino-3-methoxybenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 31 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 83 percent / conc. HCl; H2 / PtO2 / acetic acid / 760 Torr View Scheme |
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