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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Stavudine

Cas:3056-17-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Crystalline Powder Storage:-20°C Package:1kg/foil b

Factory supply Stavudine CAS 3056-17-5 with large quantity in stock

Cas:3056-17-5

Min.Order:5 Kilogram

FOB Price: $200.0 / 500.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Stavudine

Cas:3056-17-5

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Stavudine 3056-17-5 GMP Manufacturer

Cas:3056-17-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Stavudine

Cas:3056-17-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Stavudine CAS 3056-17-5

Cas:3056-17-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM-Stavudine

Cas:3056-17-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 3056-17-5 with best quality

Cas:3056-17-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

3056-17-5 Stavudine product Name Stavudine Synonyms 2',3'-didehydro-3'-deoxythymidine; 3'-deoxythymidin-2'-ene; 3'-deo

3056-17-5 Stavudine

Cas:3056-17-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

API Manufacturer Stavudine 3056-17-5 For Anti-HIV Infection

Cas:3056-17-5

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Stavudine 3056-17-5

Cas:3056-17-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Stavudine CAS:3056-17-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Stavudine CAS:3056-17-5

Cas:3056-17-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Stavudine Powder USP Standard

Cas:3056-17-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3056-17-5

Cas:3056-17-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Product name: Stavudine CAS No.: 3056-17-5 Stock: Fresh Standard: USP/EP/In-house Package:25kg drum Application:Used as an antiviral. A reverse transcriptase inhibitor

Stavudine manufacture

Cas:3056-17-5

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Hubei Yuanmeng Biological Technology Co., Ltd.

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other

High Purity Stavudine CAS 3056-17-5 with Fast Shipment

Cas:3056-17-5

Min.Order:1 Kilogram

FOB Price: $3.0 / 5.0

Type:Trading Company

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Stavudine

Cas:3056-17-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

stavudine 3056-17-5

Cas:3056-17-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Stavudine

Cas:3056-17-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

2',3'-Dideoxy-2',3'-didehydroThymidine,D4T,Stavudine司他夫定

Cas:3056-17-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Stavudine

Cas:3056-17-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Stavudine

Cas:3056-17-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging

Stavudine manufacturer

Cas:3056-17-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Stavudine

Cas:3056-17-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality Appearance:Colourless solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Used as an antiviral. A reverse transcriptase inhibi

Stavudine

Cas:3056-17-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Stavudine

Cas:3056-17-5

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Stavudine

Cas:3056-17-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: Stavudine Synonyms: STAVUDINE;3'-deoxythymidin-2'-ene;3'-DEOXY-2',3'-DIDEHYDROTHYMIDINE;ZERIT;STAVUDINE[2'',3''-DIDEHYDRO-3''-DEOXYTHYMIDINE];NSC 163661;Stavir;Thymidine, 2'', 3&

Stavudine 3056-17-5 C10H12N2O4

Cas:3056-17-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Ethylenediamine Diaceturate CAS No.: 3056-17-5 Molecule Formula:C10H14N2O4 Molecule Weight:226.23 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard T

Lower Price Ethylenediamine Diaceturate

Cas:3056-17-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Stavudine

Cas:3056-17-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1-<5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pento-2-enofuranosyl>thymine
125440-17-7

1-<5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pento-2-enofuranosyl>thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 1.5h; Ambient temperature;100%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 25℃;90%
With tetrabutyl ammonium fluoride In tetrahydrofuran Ambient temperature;78%
With tetrabutyl ammonium fluoride In tetrahydrofuran Yield given;
1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine
131933-47-6

1-<2',3'-dideoxy-3'(R)-phenylseleno-β-D-glycero-pentofuranosyl>thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid In tetrahydrofuran 1) 0 deg C, 0.25 h, 2) warm to RT, 1 h;99%
1-(5-0-Pivaloyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine
126209-27-6

1-(5-0-Pivaloyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With sodium methylate In methanol at 23℃; for 4h;95%
With buffer In ethanol at 40℃; Rate constant; hydrolysis, also enzymatic hydrolysis; various pH-values;
2,3'-anhydrothymidine
15981-92-7

2,3'-anhydrothymidine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With 1-(2-methoxyethyl)-3-methylimidazolium trifluoroacetate; sodium hydride In mineral oil at 100℃; for 0.0833333h;93%
With sodium hydride In N,N-dimethyl acetamide at 100℃; for 0.5h;81%
5'-O-benzoyl-2',3'-didehydro-3'-deoxythymidine
122567-97-9

5'-O-benzoyl-2',3'-didehydro-3'-deoxythymidine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With sodium methylate In methanol Ambient temperature;92%
With N-butylamine at 70℃; for 6h;90%
With N-butylamine90%
1-{5-[bis(4-methoxyphenyl)phenyl-methoxymethyl]-2,5-dihydrofuran-2-yl}-5-methyl-1H-pyrimidine-2,4-dione
149666-71-7

1-{5-[bis(4-methoxyphenyl)phenyl-methoxymethyl]-2,5-dihydrofuran-2-yl}-5-methyl-1H-pyrimidine-2,4-dione

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
In methanol; tetrachloromethane at 25 - 40℃; for 3h; ultrasonic;92%
With methanol; Dowex 50W H(1+) form for 0.166667h;90%
stavudine N,N-dimethylacetamide solvate

stavudine N,N-dimethylacetamide solvate

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
In water; isopropyl alcohol at 0 - 70℃; for 1.33333h; Purification / work up;91.4%
In water; acetone at 0℃; for 2.16667h; Purification / work up;76%
In water at 0 - 65℃; for 2.33333h; Purification / work up;73.7%
2',3'-didehydro-3'-deoxythymidine N,N-dimethyl propylene urea solvate
938050-90-9

2',3'-didehydro-3'-deoxythymidine N,N-dimethyl propylene urea solvate

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
Stage #1: 2',3'-didehydro-3'-deoxythymidine N,N-dimethyl propylene urea solvate In water; isopropyl alcohol at 82℃;
Stage #2: In isopropyl alcohol at 0 - 5℃; for 1.5h; Purification / work up;
87.2%
In isopropyl alcohol at 0 - 82℃; for 1.5h; Product distribution / selectivity;87.2%
Stage #1: 2',3'-didehydro-3'-deoxythymidine N,N-dimethyl propylene urea solvate In water; acetone at 55℃;
Stage #2: In acetone at 0 - 40℃; for 1h; Purification / work up;
84%
1-(5-O-acetyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)-thymine
77421-68-2

1-(5-O-acetyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)-thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With sodium methylate In methanol for 2h; Ambient temperature;87%
With sodium hydroxide In acetonitrile for 0.5h; Yield given;
With buffer In ethanol at 40℃; Rate constant; hydrolysis, also enzymatic hydrolysis; various pH-values;
1-(2,3-dideoxy-3-C-selenophenyl-β-D-erythro-pentofuranosyl)thymine
131933-44-3

1-(2,3-dideoxy-3-C-selenophenyl-β-D-erythro-pentofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid In tetrahydrofuran 1) 0 deg C, 0.25 h, 2) warm to RT, 1 h;86%
hydrated p-toluene sulfonate

hydrated p-toluene sulfonate

tributyl-amine
102-82-9

tributyl-amine

ammonium hydroxide

ammonium hydroxide

5-Methyluridine
1463-10-1

5-Methyluridine

trimethyl orthoformate
149-73-5

trimethyl orthoformate

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With sodium methylate; acetic anhydride; sodium carbonate; hydrous zirconium oxide In methanol86%
3',4'-anhydrothymidine
7481-90-5

3',4'-anhydrothymidine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With potassium hydroxide In tert-butyl alcohol at 55 - 60℃; for 2h;85%
With sodium hydride In N,N-dimethyl acetamide at 100℃; for 0.75h;76%
With potassium tert-butylate In dimethyl sulfoxide at 21℃; for 17h;57%
1-(5-O-tert-butyldimethylsilyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine
119794-55-7

1-(5-O-tert-butyldimethylsilyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran80%
5'-O-t-butyl-dimethylsilyl-3'-O-methanesulfonyl-thymidine
117383-83-2

5'-O-t-butyl-dimethylsilyl-3'-O-methanesulfonyl-thymidine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide for 0.5h; Ambient temperature;80%
1-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl-5-O-trityl)thymine
5964-41-0

1-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl-5-O-trityl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With acetic acid at 50℃; for 1h;71%
With acetic acid In water at 80 - 90℃; for 1h;67%
With acetic acid
5'-O-(4-Methoxybenzyl)-2',3'-didehydro-2',3'-dideoxy-N3-(4-methoxybenzyl)-5-methyluridine
161824-93-7

5'-O-(4-Methoxybenzyl)-2',3'-didehydro-2',3'-dideoxy-N3-(4-methoxybenzyl)-5-methyluridine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In acetonitrile for 3h; Ambient temperature;68%
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
4336-39-4

(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
Stage #1: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate With palladium diacetate; lithium bromide In N,N-dimethyl-formamide at 180℃; for 36h; Inert atmosphere;
Stage #2: With sodium methylate In methanol at 20℃; for 3h; Concentration; Temperature; Reagent/catalyst; Solvent;
68%
1-(5-O-tert-butyldiphenylsilyl-2-deoxy-3-O-p-toluenesulfonyl-β-D-erythro-pentofuranosyl)thymine
152039-45-7

1-(5-O-tert-butyldiphenylsilyl-2-deoxy-3-O-p-toluenesulfonyl-β-D-erythro-pentofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 48h; Heating;60%
With tetrabutyl ammonium fluoride In tetrahydrofuran for 24h; Heating; Yield given;
1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)thymine
110483-43-7

1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With copper; zinc In methanol for 0.5h;53%
Multi-step reaction with 2 steps
1: tetraethylammonium p-toluenesulfonate / methanol / 1 h / Electrolysis; Pt plate anode, Hg pool cathode
2: NH4OH
View Scheme
Multi-step reaction with 2 steps
1: 1.) zinc powder, 2.) aq. EDTA sodium salt / 1.) CH3CN, RT, 2 h
2: aq. NaOH / acetonitrile / 0.5 h
View Scheme
Multi-step reaction with 2 steps
1: 53 percent / Zn/Cu / methanol / 0.5 h
2: 87 percent / sodium methoxide / methanol / 2 h / Ambient temperature
View Scheme
1-(5-O-tert-butyldiphenylsilyl-2-deoxy-3-O-methylsulfonyl-α,β-D-erythro-pentofuranosyl)thymine
139212-94-5, 139212-95-6

1-(5-O-tert-butyldiphenylsilyl-2-deoxy-3-O-methylsulfonyl-α,β-D-erythro-pentofuranosyl)thymine

A

2,3'-anhydrothymidine
15981-92-7

2,3'-anhydrothymidine

B

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 24h; Ambient temperature;A 52%
B 17%
1-(2',3'-dideoxy-2'-iodo-5'-O-(trimethylacetyl)-β-D-ribofuranosyl)thymine
144867-91-4

1-(2',3'-dideoxy-2'-iodo-5'-O-(trimethylacetyl)-β-D-ribofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With sodium methylate In methanol48%
With sodium methylate In methanol at 20℃; for 18h; Yield given;
Multi-step reaction with 3 steps
1: DBU / CH2Cl2 / 1 h / 0 °C
2: 82 percent / potassium t-butoxide / tetrahydrofuran / 1 h / 0 °C
3: 95 percent / sodium methoxide / methanol / 4 h / 23 °C
View Scheme
1-(3,5-anhydro-2-deoxy-β-D-threo-pentofuranosyl)-2-O-ethylthymine
155807-21-9

1-(3,5-anhydro-2-deoxy-β-D-threo-pentofuranosyl)-2-O-ethylthymine

A

2-methyl-5-(thymin-1-yl)furan
5983-11-9

2-methyl-5-(thymin-1-yl)furan

B

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With potassium tert-butylate In dimethyl sulfoxide for 1h; Ambient temperature;A 32.5%
B 3.5%
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

3',4'-anhydrothymidine
7481-90-5

3',4'-anhydrothymidine

A

1-((2R,4R,5R)-4-Hydroxy-5-pentyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione
124685-30-9

1-((2R,4R,5R)-4-Hydroxy-5-pentyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

B

thymin
65-71-4

thymin

C

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -70℃; for 1h;A 31%
B 18%
C 13%
tert.-butyl lithium
594-19-4

tert.-butyl lithium

3',4'-anhydrothymidine
7481-90-5

3',4'-anhydrothymidine

A

1-[(2R,4R,5R)-5-(2,2-Dimethyl-propyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione
124685-31-0

1-[(2R,4R,5R)-5-(2,2-Dimethyl-propyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

B

1-(2,5-dideoxy-β-D-threo-pentofuranosyl)thymine
118778-33-9

1-(2,5-dideoxy-β-D-threo-pentofuranosyl)thymine

C

thymin
65-71-4

thymin

D

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In tetrahydrofuran; pentane at -70℃; for 1h; Yields of byproduct given;A 26%
B n/a
C 27%
D n/a
With boron trifluoride diethyl etherate In tetrahydrofuran; pentane at -70℃; for 1h; Yield given. Yields of byproduct given;A 26%
B n/a
C 27%
D n/a
With boron trifluoride diethyl etherate In tetrahydrofuran; pentane at -70℃; for 1h; Yield given;A 26%
B n/a
C 27%
D n/a
Acetic acid (2R,3R,4R,5R)-4-bromo-2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

Acetic acid (2R,3R,4R,5R)-4-bromo-2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

A

(E)-1-(3(S),4(R),5-trihydroxypent-1-en-1-yl)thymine
127516-98-7

(E)-1-(3(S),4(R),5-trihydroxypent-1-en-1-yl)thymine

B

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With ammonia; copper; acetic acid; zinc 1.) DMF, RT, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine
42214-24-4

1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine

A

stavudin
3056-17-5

stavudin

B

alovudine
25526-93-6

alovudine

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride; acetic acid 1.) THF, RT, 32 h, 2.) 110 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;
With diethylamino-sulfur trifluoride; acetic acid 1.) THF, benzene, 2 h, 2.) 100 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;
1-(2-deoxy-3,5-epoxy-β-D-threo-pentofuranosyl)thymine
38313-48-3

1-(2-deoxy-3,5-epoxy-β-D-threo-pentofuranosyl)thymine

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With potassium tert-butylate In dimethyl sulfoxide
With potassium hydroxide In isopropyl alcohol Rearrangement;
Octanoic acid (2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester

Octanoic acid (2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With buffer In ethanol at 40℃; Rate constant; hydrolysis, also enzymatic hydrolysis; various pH-values;
2',3'-didehydro-3'-deoxythymidine 5'-O-hemisuccinate
152336-78-2

2',3'-didehydro-3'-deoxythymidine 5'-O-hemisuccinate

stavudin
3056-17-5

stavudin

Conditions
ConditionsYield
With buffer In ethanol at 40℃; Rate constant; hydrolysis, also enzymatic hydrolysis; various pH-values;

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