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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Homovanillic acid Manufacturer/High quality/Best price/In stock

Cas:306-08-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Homovanillic Acid supplier in China

Cas:306-08-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Homovanillic Acid

Cas:306-08-1

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Homovanillic acid 306-08-1 Producer

Cas:306-08-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Homovanillic acid

Cas:306-08-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Homovanillic acid 306-08-1

Cas:306-08-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 306-08-1 with best price

Cas:306-08-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Homovanillic acid 306-08-1

Cas:306-08-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Homovanillic acid 306-08-1

Cas:306-08-1

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Animal Pharmaceuticals, Homovanillic acid CAS:306-08-1

Cas:306-08-1

Min.Order:1 Kilogram

FOB Price: $37.4 / 42.8

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Homovanillic acid CAS:306-08-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

Homovanillic acid CAS:306-08-1

Cas:306-08-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Homovanillic acid

Cas:306-08-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:306-08-1

Cas:306-08-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Homovanillic Acid

Cas:306-08-1

Min.Order:0

Negotiable

Type:Manufacturers

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Chengdu Biopurify Phytochemicals Ltd.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic

Homovanillic acid

Cas:306-08-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Homovanillic acid

Cas:306-08-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

Homovanillic Acid

Cas:306-08-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging

Homovanillic acid manufacturer

Cas:306-08-1

Min.Order:1 Gram

Negotiable

Type:Other

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Shanghai Send Pharmaceutical Technology Co., Ltd.

low price high quality high purity good sevice stock Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical intermediat

Homovanillic acid

Cas:306-08-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Homovanillic Acid

Cas:306-08-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white to beige crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Applicatio

Homovanillic acid

Cas:306-08-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

homovanillic acid.99%

Cas:306-08-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Homovanillic acid Basic information Product Name: Homovanillic acid Synonyms: 4-Hydroxy-3-methoxybenzeneacetic acid;4-hydroxy-3-methoxy-benzeneaceticaci;4-hydroxy-3-methoxy-Benzeneaceticacid;Acetic acid, (4-hydroxy-3-methoxyphenyl)-;Homovanili

Homovanillic acid

Cas:306-08-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

Homovanillic acid

Cas:306-08-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Homovanillic acid

Cas:306-08-1

Min.Order:0

Negotiable

Type:Other

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Homovanillic acid

Cas:306-08-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Supply Homovanillic acid/CAS NO.:306-08-1

Cas:306-08-1

Min.Order:0

Negotiable

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:White to off-white solid Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Hydroxy-3-methoxyphenylacetic acid cas no. 306-08-1 98%

Cas:306-08-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

shanghai Tauto Biotech Co., Ltd

The quality is guaranteed. If you find the product is wrong compared with COA, we promise 100% refund or change product. COA and HPLC will be shipped out with goods. You can also inform your analysis method and we will follow your analysis me

Homovanillic acid

Cas:306-08-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Greenutra Resource Inc

Homovanillic acidAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

Homovanillic acid

Cas:306-08-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-hydroxy-3-methoxyphenylacetonitrile
4468-59-1

4-hydroxy-3-methoxyphenylacetonitrile

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 80℃; for 48h; Inert atmosphere;89%
With potassium hydroxide In ethanol Heating;74%
With sodium hydroxide In 2-methoxy-ethanol
4-hydroxy-3-methoxy-mandelic acid
55-10-7

4-hydroxy-3-methoxy-mandelic acid

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With hydrogenchloride; tin(ll) chloride In water at 80℃; for 4h;88%
75%
With 5%-palladium/activated carbon; hydrogen; acetic acid In water
3-methoxy-4-hydroxy mandelic acid
13244-77-4

3-methoxy-4-hydroxy mandelic acid

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With formic acid; phosphoric acid; sodium hydrogensulfite In water at 100℃; under 3750.3 Torr; for 9h;71%
4-Acetoxy-3-methoxyphenylacetaldehyde
6391-59-9

4-Acetoxy-3-methoxyphenylacetaldehyde

A

Homovanillic acid
306-08-1

Homovanillic acid

B

2-(4-acetoxy-3-methoxyphenyl)acetic acid
5447-38-1

2-(4-acetoxy-3-methoxyphenyl)acetic acid

Conditions
ConditionsYield
With potassium permanganate; magnesium sulfate; acetone
4-(4-acetoxy-3-methoxy-benzylidene)-2-methyl-4H-oxazol-5-one
60470-82-8, 39600-31-2

4-(4-acetoxy-3-methoxy-benzylidene)-2-methyl-4H-oxazol-5-one

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With sodium hydroxide anschliessend Behandeln mit wss. H2O2;
2-(4-acetoxy-3-methoxyphenyl)acetic acid
5447-38-1

2-(4-acetoxy-3-methoxyphenyl)acetic acid

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With sodium hydroxide
m-methoxy-p-acetoxy-α-benzoylaminocinnamic acid azlactone
18692-68-7, 71413-82-6, 74857-79-7

m-methoxy-p-acetoxy-α-benzoylaminocinnamic acid azlactone

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
folgend Behandeln mit Wasserstoffperoxyd in Eisessig;
(4-acetoxy-3-methoxy-phenyl)-acetonitrile
5438-51-7

(4-acetoxy-3-methoxy-phenyl)-acetonitrile

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With potassium hydroxide
1-benzoyloxy-4-chloromethyl-2-methoxy-benzene
873376-14-8

1-benzoyloxy-4-chloromethyl-2-methoxy-benzene

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With potassium cyanide anschliessend Erhitzen mit wss. Natronlauge;

A

Homovanillic acid
306-08-1

Homovanillic acid

B

5-[2-(4-Hydroxy-3-methoxy-phenyl)-ethyl]-dihydro-furan-2-one

5-[2-(4-Hydroxy-3-methoxy-phenyl)-ethyl]-dihydro-furan-2-one

Conditions
ConditionsYield
for 168h; biotransformation by aspergillus niger;A 60 mg
B 36 mg
4-benzyloxy-3-methoxyphenylacetic acid
29973-91-9

4-benzyloxy-3-methoxyphenylacetic acid

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol
trans-coniferyl aldehyde
458-36-6

trans-coniferyl aldehyde

A

methoxyhydroquinone
824-46-4

methoxyhydroquinone

B

3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

C

Homovanillic acid
306-08-1

Homovanillic acid

D

vanillin
121-33-5

vanillin

Conditions
ConditionsYield
With peracetic acid In ethanol for 1h; pH=7; Product distribution; Further Variations:; Reagents; Oxidation;A 10.1 % Chromat.
B 13.6 % Chromat.
C 10.9 % Chromat.
D 7.1 % Chromat.
4-Acetoxy-3-methoxyphenylacetaldehyde
6391-59-9

4-Acetoxy-3-methoxyphenylacetaldehyde

magnesium sulfate
7487-88-9

magnesium sulfate

acetone
67-64-1

acetone

KMnO4

KMnO4

A

Homovanillic acid
306-08-1

Homovanillic acid

B

2-(4-acetoxy-3-methoxyphenyl)acetic acid
5447-38-1

2-(4-acetoxy-3-methoxyphenyl)acetic acid

azlactone of/the/ 3-methoxy-4-acetoxy-α-benzamino-cinnamic acid

azlactone of/the/ 3-methoxy-4-acetoxy-α-benzamino-cinnamic acid

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
With sodium hydroxide man gibt zu der Loesung erst Eisessig und dann H2O2;
(3-methoxy-4-oxo-cyclohexa-2,5-dienyliden)-acetonitrile
91054-36-3

(3-methoxy-4-oxo-cyclohexa-2,5-dienyliden)-acetonitrile

hydrogen iodide
10034-85-2

hydrogen iodide

A

Homovanillic acid
306-08-1

Homovanillic acid

B

2,3-bis-(4-hydroxy-3-methoxy-phenyl)-succinonitrile

2,3-bis-(4-hydroxy-3-methoxy-phenyl)-succinonitrile

Conditions
ConditionsYield
5-min. Erhitzen;
4-amino-butyric acid 2-(4-hydroxy-3-methoxy-phenyl)-2-oxo-ethyl ester
284043-11-4

4-amino-butyric acid 2-(4-hydroxy-3-methoxy-phenyl)-2-oxo-ethyl ester

A

Homovanillic acid
306-08-1

Homovanillic acid

B

2,4'-dihydroxy-3'-methoxyacetophenone
18256-48-9

2,4'-dihydroxy-3'-methoxyacetophenone

C

1-(3-methoxy-4-hydroxyphenyl)ethanone
498-02-2

1-(3-methoxy-4-hydroxyphenyl)ethanone

D

4-amino-n-butyric acid
56-12-2

4-amino-n-butyric acid

Conditions
ConditionsYield
With water Hydrolysis; reduction; rearrangement; UV-irradiation;
γ-O-(4-hydroxy-3-methoxyphenacetyl) L-glutamate, trifuoroacetate salt

γ-O-(4-hydroxy-3-methoxyphenacetyl) L-glutamate, trifuoroacetate salt

A

L-glutamic acid
56-86-0

L-glutamic acid

B

Homovanillic acid
306-08-1

Homovanillic acid

C

2,4'-dihydroxy-3'-methoxyacetophenone
18256-48-9

2,4'-dihydroxy-3'-methoxyacetophenone

D

1-(3-methoxy-4-hydroxyphenyl)ethanone
498-02-2

1-(3-methoxy-4-hydroxyphenyl)ethanone

Conditions
ConditionsYield
With water Hydrolysis; rearrangement; reduction; UV-irradiation;
4-hydroxymethyl-2-methoxyphenol
498-00-0

4-hydroxymethyl-2-methoxyphenol

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60 percent / dimethylformamide / 20 h / 130 °C
2: 74 percent / KOH / ethanol / Heating
View Scheme
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide / 24 h / 120 °C / Inert atmosphere
2: sodium hydroxide / ethanol; water / 48 h / 80 °C / Inert atmosphere
View Scheme
α-bromo-3-methoxy-4-hydroxyacetophenone
69638-06-8

α-bromo-3-methoxy-4-hydroxyacetophenone

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: DBU / dioxane / 12 h / 0 - 20 °C
2: TFA / 4 h / 0 °C
3: H2O / UV-irradiation
View Scheme
Multi-step reaction with 3 steps
1: 57 percent / DBU / benzene / 12 h / 20 °C
2: 95.3 percent / TFA / 4 h / 0 °C
3: H2O / UV-irradiation
View Scheme
1-(3-methoxy-4-hydroxyphenyl)ethanone
498-02-2

1-(3-methoxy-4-hydroxyphenyl)ethanone

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 47 percent / cupric bromide / CHCl3; ethyl acetate / 4 h / 20 °C
2: DBU / dioxane / 12 h / 0 - 20 °C
3: TFA / 4 h / 0 °C
4: H2O / UV-irradiation
View Scheme
Multi-step reaction with 4 steps
1: 47 percent / cupric bromide / CHCl3; ethyl acetate / 4 h / 20 °C
2: 57 percent / DBU / benzene / 12 h / 20 °C
3: 95.3 percent / TFA / 4 h / 0 °C
4: H2O / UV-irradiation
View Scheme
2-(4-hydroxy-3-methoxyphenyl)-2-oxoethyl-4-[(tert-butoxycarbonyl)amino]butanoate
284043-13-6

2-(4-hydroxy-3-methoxyphenyl)-2-oxoethyl-4-[(tert-butoxycarbonyl)amino]butanoate

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: TFA / 4 h / 0 °C
2: H2O / UV-irradiation
View Scheme
γ-O-(4-hydroxy-3-methoxyphenacetyl) t-butyl N-t-boc L-glutamate
284043-05-6

γ-O-(4-hydroxy-3-methoxyphenacetyl) t-butyl N-t-boc L-glutamate

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95.3 percent / TFA / 4 h / 0 °C
2: H2O / UV-irradiation
View Scheme
methyl 4-benzyloxy-3-methoxyphenylethanoate
16209-54-4

methyl 4-benzyloxy-3-methoxyphenylethanoate

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 10percent KOH / methanol; H2O
2: H2 / 10percent Pd-C / aq. ethanol
View Scheme
4-(hydroxymethyl)-2-methoxyphenyl benzoate
174840-51-8

4-(hydroxymethyl)-2-methoxyphenyl benzoate

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: calcium chloride; thionyl chloride
2: aqueous potassium cyanide / anschliessend Erhitzen mit wss. Natronlauge
View Scheme
eugenol acetate
93-28-7

eugenol acetate

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ethyl acetate; ozone / und anschliesende Hydrierung an Palladium/Kohle
2: potassium permanganate; magnesium sulfate; aqueous acetone
View Scheme
Multi-step reaction with 2 steps
1: KMnO4; water
2: NaOH-solution
View Scheme
4-allylguaiacol
97-53-0

4-allylguaiacol

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
2: KMnO4; water
3: NaOH-solution
View Scheme
2-methoxy-4-((methylamino)methyl)phenol
42973-53-5

2-methoxy-4-((methylamino)methyl)phenol

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dimethylformamide
2: aq. NaOH / 2-methoxy-ethanol
View Scheme
vanillin
121-33-5

vanillin

Homovanillic acid
306-08-1

Homovanillic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (i) EtOH, (ii) H2, PtO2
2: dimethylformamide
3: aq. NaOH / 2-methoxy-ethanol
View Scheme
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / 24.5 h / 0 - 20 °C / Inert atmosphere
2: N,N-dimethyl-formamide / 24 h / 120 °C / Inert atmosphere
3: sodium hydroxide / ethanol; water / 48 h / 80 °C / Inert atmosphere
View Scheme
8-O-4′-diferulic acid
215872-63-2

8-O-4′-diferulic acid

A

3-(4-hydroxy-3-methoxyphenyl)acrylic acid
1135-24-6

3-(4-hydroxy-3-methoxyphenyl)acrylic acid

B

3-(3-hydroxyphenyl)-propanoic acid
621-54-5

3-(3-hydroxyphenyl)-propanoic acid

C

3-(4-hydroxy-3-methoxyphenyl)propionic acid
1135-23-5

3-(4-hydroxy-3-methoxyphenyl)propionic acid

D

caffeic acid
331-39-5

caffeic acid

E

3,4-dihydroxyphenylacetate
102-32-9

3,4-dihydroxyphenylacetate

F

Homovanillic acid
306-08-1

Homovanillic acid

G

dihydrocaffeic acid
1078-61-1

dihydrocaffeic acid

H

danshensu
23028-17-3

danshensu

I

3-(4-hydroxy-3-methoxyphenyl)lactic acid
2475-56-1

3-(4-hydroxy-3-methoxyphenyl)lactic acid

J

3-(4-hydroxy-3-methoxyphenyl)-2-oxopropanoic acid
1081-71-6

3-(4-hydroxy-3-methoxyphenyl)-2-oxopropanoic acid

Conditions
ConditionsYield
With D-glucose In dimethyl sulfoxide at 37℃; aq. buffer; anaerobic atmosphere; Enzymatic reaction;
methanol
67-56-1

methanol

Homovanillic acid
306-08-1

Homovanillic acid

2-(4-hydroxy-3-methoxyphenyl)acetic acid methyl ester
15964-80-4

2-(4-hydroxy-3-methoxyphenyl)acetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid for 3h; Reflux;100%
With toluene-4-sulfonic acid
With sulfuric acid at 20℃; for 4h; Reflux;
Homovanillic acid
306-08-1

Homovanillic acid

isopropyl bromide
75-26-3

isopropyl bromide

isopropyl 2-(4-isopropoxy-3-methoxyphenyl)acetate
1256581-67-5

isopropyl 2-(4-isopropoxy-3-methoxyphenyl)acetate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 24h; Reflux; Inert atmosphere;100%
Homovanillic acid
306-08-1

Homovanillic acid

recorcinol
108-46-3

recorcinol

1-(2,4-dihydroxyphenyl)-2-(4'-hydroxy-3'-methoxyphenyl)ethanone
40456-49-3

1-(2,4-dihydroxyphenyl)-2-(4'-hydroxy-3'-methoxyphenyl)ethanone

Conditions
ConditionsYield
With boron trifluoride diethyl etherate at 60 - 70℃; for 1h;99%
With bis(trifluoromethanesulfonyl)amide In various solvent(s) at 90℃; for 0.0666667h; Friedel-Crafts reaction; microwave irradiation;70%
With boron trifluoride diethyl etherate In N,N-dimethyl-formamide at 120℃; for 0.166667h; Friedel-Crafts reaction;57%
ethanol
64-17-5

ethanol

Homovanillic acid
306-08-1

Homovanillic acid

ethyl homovanillate
60563-13-5

ethyl homovanillate

Conditions
ConditionsYield
With sulfuric acid for 2h; Reflux;99%
With sulfuric acid99%
With sulfuric acid for 2h; Reflux;80%
With sulfuric acid Reflux;
With sulfuric acid at 90℃; for 7h;
Homovanillic acid
306-08-1

Homovanillic acid

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-butyldimethyl 2-(4-(tert-butyldimethylsilyloxy)-3-methoxyphenyl)acetate
78324-15-9

tert-butyldimethyl 2-(4-(tert-butyldimethylsilyloxy)-3-methoxyphenyl)acetate

Conditions
ConditionsYield
With 1H-imidazole In tetrahydrofuran at 20℃; for 14h; Inert atmosphere;98%
With 1H-imidazole In tetrahydrofuran at 20℃; for 14h; Inert atmosphere;64%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 3h;
Homovanillic acid
306-08-1

Homovanillic acid

2-(3,4-dihydroxy-5-methoxyphenyl)acetic acid
2989-10-8

2-(3,4-dihydroxy-5-methoxyphenyl)acetic acid

Conditions
ConditionsYield
With Agaricus bisporus; oxygen In aq. phosphate buffer; dichloromethane at 25℃; for 24h; pH=7;98%
Homovanillic acid
306-08-1

Homovanillic acid

acetic anhydride
108-24-7

acetic anhydride

2-(4-acetoxy-3-methoxyphenyl)acetic acid
5447-38-1

2-(4-acetoxy-3-methoxyphenyl)acetic acid

Conditions
ConditionsYield
With sulfuric acid97%
With sulfuric acid Ambient temperature;79%
2-(methylamino)-1-phenylethanol
68579-60-2

2-(methylamino)-1-phenylethanol

Homovanillic acid
306-08-1

Homovanillic acid

2-(4-hydroxy-3-methoxy-phenyl)-N-(2-hydroxy-2-phenyl-ethyl)-N-methyl-acetamide
749247-36-7

2-(4-hydroxy-3-methoxy-phenyl)-N-(2-hydroxy-2-phenyl-ethyl)-N-methyl-acetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane97%
4-Methylbenzyl alcohol
589-18-4

4-Methylbenzyl alcohol

Homovanillic acid
306-08-1

Homovanillic acid

1-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl)propan-2-one

1-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl)propan-2-one

Conditions
ConditionsYield
Stage #1: 4-Methylbenzyl alcohol; Homovanillic acid With dmap; dicyclohexyl-carbodiimide In 1,2-dichloro-ethane at 55℃; for 4h;
Stage #2: With sodium tetrahydroborate In tetrahydrofuran for 2h; Temperature; Inert atmosphere; Cooling with ice;
96.8%
Homovanillic acid
306-08-1

Homovanillic acid

benzyl bromide
100-39-0

benzyl bromide

benzyl 2-(4-(benzyloxy)-3-methoxyphenyl)acetate
65340-85-4

benzyl 2-(4-(benzyloxy)-3-methoxyphenyl)acetate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 4h; Reflux;95%
With potassium carbonate In acetonitrile at 80℃; for 8h;88%
With sodium In methanol
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

Homovanillic acid
306-08-1

Homovanillic acid

2-(3-methoxy-4-(trifluoromethylsulfonyloxy)phenyl)acetic acid
1243245-99-9

2-(3-methoxy-4-(trifluoromethylsulfonyloxy)phenyl)acetic acid

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃;95%
Homovanillic acid
306-08-1

Homovanillic acid

4-Methoxyphenethylamine
55-81-2

4-Methoxyphenethylamine

2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]acetamide
1395084-66-8

2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]acetamide

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene for 16h; Reflux; Inert atmosphere;95%
Homovanillic acid
306-08-1

Homovanillic acid

N-(benzyloxy)octan-1-amine
122149-21-7

N-(benzyloxy)octan-1-amine

N-benzyloxy-N-octyl-2-(4-hydroxy-3-methoxyphenyl)acetamide
1400943-51-2

N-benzyloxy-N-octyl-2-(4-hydroxy-3-methoxyphenyl)acetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 4.5h; Inert atmosphere;94%
Homovanillic acid
306-08-1

Homovanillic acid

O-benzyl-N-heptylhydroxylamine
112151-61-8

O-benzyl-N-heptylhydroxylamine

N-benzyloxy-N-heptyl-2-(4-hydroxy-3-methoxyphenyl)acetamide
1400943-49-8

N-benzyloxy-N-heptyl-2-(4-hydroxy-3-methoxyphenyl)acetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane93%
Homovanillic acid
306-08-1

Homovanillic acid

Phenyl-acetic acid (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-acetoxy-4a,7b-dihydroxy-3-hydroxymethyl-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl ester
850163-67-6

Phenyl-acetic acid (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-acetoxy-4a,7b-dihydroxy-3-hydroxymethyl-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl ester

13-acetyl-20-homovanillyl-12-phenylacetyl-4α-phorbol
777859-96-8

13-acetyl-20-homovanillyl-12-phenylacetyl-4α-phorbol

Conditions
ConditionsYield
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 1h;91%
Å molecular sieve

Å molecular sieve

Homovanillic acid
306-08-1

Homovanillic acid

3-(3,4-dimethylphenyl)propylamine
142332-70-5

3-(3,4-dimethylphenyl)propylamine

KR-25003
142333-36-6

KR-25003

Conditions
ConditionsYield
In dichloromethane90%
Homovanillic acid
306-08-1

Homovanillic acid

3-(3,4-dimethylphenyl)propylamine
142332-70-5

3-(3,4-dimethylphenyl)propylamine

KR-25003
142333-36-6

KR-25003

Conditions
ConditionsYield
molecular sieve In dichloromethane90%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 15h;
Homovanillic acid
306-08-1

Homovanillic acid

benzylamine
100-46-9

benzylamine

N-benzyl-4-hydroxy-3-methoxyphenylacetamide
391609-30-6

N-benzyl-4-hydroxy-3-methoxyphenylacetamide

Conditions
ConditionsYield
With 4 A molecular sieve at 140 - 150℃; for 3h;89%
Homovanillic acid
306-08-1

Homovanillic acid

3-iodobenzylamine hydrochloride
3718-88-5

3-iodobenzylamine hydrochloride

2-(4-hydroxy-3-methoxyphenyl)-N-(3-iodobenzyl)acetamide
873099-30-0

2-(4-hydroxy-3-methoxyphenyl)-N-(3-iodobenzyl)acetamide

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; triethylamine; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;88%
Homovanillic acid
306-08-1

Homovanillic acid

2-(3-methoxyphenyl)-1-ethanamine
2039-67-0

2-(3-methoxyphenyl)-1-ethanamine

2-(4-hydroxy-3-methoxyphenyl)-N-[2-(3-methoxyphenyl)ethyl]acetamide

2-(4-hydroxy-3-methoxyphenyl)-N-[2-(3-methoxyphenyl)ethyl]acetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 70℃; for 4h;88%
methanol
67-56-1

methanol

Homovanillic acid
306-08-1

Homovanillic acid

trimethyl orthoformate
149-73-5

trimethyl orthoformate

2-(4-hydroxy-3-methoxyphenyl)acetic acid methyl ester
15964-80-4

2-(4-hydroxy-3-methoxyphenyl)acetic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid for 18h; Heating / reflux;85%
3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indole
844901-56-0

3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indole

Homovanillic acid
306-08-1

Homovanillic acid

4-(2-{3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}-2-oxoethyl)-2-methoxyphenol
847064-35-1

4-(2-{3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}-2-oxoethyl)-2-methoxyphenol

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In 1,2-dichloro-ethane at 0 - 20℃;82%
8-methyl-1-nonanol
55505-26-5

8-methyl-1-nonanol

Homovanillic acid
306-08-1

Homovanillic acid

8-methylnonyl homovanillate
951221-76-4

8-methylnonyl homovanillate

Conditions
ConditionsYield
With magnesium sulfate; novozyme 435 In toluene at 50℃; for 16h; Enzymatic reaction;81.5%
Homovanillic acid
306-08-1

Homovanillic acid

2-(3,4-dimethoxyphenyl)-ethylamine
120-20-7

2-(3,4-dimethoxyphenyl)-ethylamine

N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(3-hydroxy-4-methoxyphenyl)acetamide
361389-65-3

N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(3-hydroxy-4-methoxyphenyl)acetamide

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;79%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;79%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃;
propan-1-ol
71-23-8

propan-1-ol

Homovanillic acid
306-08-1

Homovanillic acid

Propyl-2-(4-hydroxy-3-methoxy-phenyl)acetate
52744-26-0

Propyl-2-(4-hydroxy-3-methoxy-phenyl)acetate

Conditions
ConditionsYield
With acetyl chloride at 60℃; for 3h;78.2%
With sulfuric acid at 90℃; for 7h;
2-phenylethanol
60-12-8

2-phenylethanol

Homovanillic acid
306-08-1

Homovanillic acid

2-phenylethyl 2-(4-hydroxy-3-methoxyphenyl)acetate

2-phenylethyl 2-(4-hydroxy-3-methoxyphenyl)acetate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; thiamine diphosphate In tetrahydrofuran at 20℃; Mitsunobu esterification;78%
2-Phenoxyethanol
122-99-6

2-Phenoxyethanol

Homovanillic acid
306-08-1

Homovanillic acid

2-phenoxyethyl 2-(4-hydroxy-3-methoxyphenyl)acetate

2-phenoxyethyl 2-(4-hydroxy-3-methoxyphenyl)acetate

Conditions
ConditionsYield
With sulfuric acid In toluene for 2h; Dean-Stark; Reflux;77.3%
piperidine
110-89-4

piperidine

Homovanillic acid
306-08-1

Homovanillic acid

2-(4-Hydroxy-3-methoxy-phenyl)-1-piperidin-1-yl-ethanone
53283-49-1

2-(4-Hydroxy-3-methoxy-phenyl)-1-piperidin-1-yl-ethanone

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 3h;75%

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