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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality diethyl (hydroxymethyl)phosphonate supplier in China

Cas:3084-40-0

Min.Order:1 Metric Ton

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Diethyl (hydroxymethyl)phosphonate CAS NO.3084-40-0

Cas:3084-40-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Hydroxymethyl Diethyl Phosphonate

Cas:3084-40-0

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Phosphonic acid,P-(hydroxymethyl)-, diethyl ester 3084-40-0 ISO Manufacturer

Cas:3084-40-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(Hydroxymethyl)-phosphonic acid diethyl ester

Cas:3084-40-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:iethyl (hydroxymethyl)phosphonate CAS:3084-40-0 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security withou

High quality diethyl (hydroxymethyl)phosphonate supplier in China

Cas:3084-40-0

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

CAS:3084-40-0 Diethyl (hydroxymethyl) Phosphonate

Cas:3084-40-0

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Henan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the com

TIANFU-CHEM - Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Gram

FOB Price: $1000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 3084-40-0 with best quality

Cas:3084-40-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 4-Hydroxymethyldiethylphosphonate Synonyms: diethyl (hydroxymethyl)phosphonate CAS:3084-40-0 MF: C5H13O4P Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Organic synthesis Trans

4-Hydroxymethyldiethylphosphonate

Cas:3084-40-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 3084-40-0 Diethyl (hydroxymethyl)phosphonate with best price

Cas:3084-40-0

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Phosphonic acid,P-(hydroxymethyl)-, diethyl ester 3084-40-0

Cas:3084-40-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Diethyl (hydroxymethyl)phosphonate CAS:3084-40-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

Diethyl (hydroxymethyl)phosphonate CAS:3084-40-0

Cas:3084-40-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3084-40-0

Cas:3084-40-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phosphonic acid,P-(hydroxymethyl)-, diethyl ester

Cas:3084-40-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Hydroxymethyl Diethyl Phosphonate

Cas:3084-40-0

Min.Order:0

Negotiable

Type:Manufacturers

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality moderate price & quick delivery Appearance:Clear colorless to yellow viscous liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. App

Phosphonic acid,P-(hydroxymethyl)-, diethyl ester

Cas:3084-40-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:0 Metric Ton

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

DIETHYL (HYDROXYMETHYL) PHOSPHONATE

Cas:3084-40-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

diethyl(hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:0

Negotiable

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Hangzhou Lingrui Chemical Co.,Ltd.

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: Diethyl(Hydroxymethyl)Phosphonate CAS No.:3084-40-0 Molecule Formula:C5H13O4P Molecule Weight:168.13 Purity: 99.0% Package: 200kg/drum Description:Light yellow or colorless oily liquid Manufacture Standards:Enterprise St

Best Quality Diethyl(Hydroxymethyl)Phosphonate

Cas:3084-40-0

Min.Order:1 Kilogram

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Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Metric Ton

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Quality Manufacturer Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:0

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Diethyl(hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

Product Name: Diethyl (hydroxymethyl)phosphonate Synonyms: AURORA KA-1421;DIETHYL HYDROXYMETHYLPHOSPHONATE;(Hydroxymethyl)phosphonic acid, diethyl ester;(hydroxymethyl)-phosphonicacidiethylester;Phosphonic acid, (hydroxymethyl)-, diethyl ester

Diethyl (hydroxymethyl)phosphonate 3084-40-0 C5H13O4P

Cas:3084-40-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Diethyl (hydroxymethyl)phosphonate

Cas:3084-40-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

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Synthetic route

formaldehyd
50-00-0

formaldehyd

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
With triethylamine at 90℃; for 3h; Reflux;96%
With potassium carbonate In ethanol at 75℃; for 5h;95%
With potassium carbonate In toluene at 60℃; for 2.25h; pH=7.5 - 8;95%
(diethoxyphosphoryl)methyl acetate
7016-78-6

(diethoxyphosphoryl)methyl acetate

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
With sodium ethanolate In ethanol90%
formaldehyd
50-00-0

formaldehyd

Diethyl phosphonate
762-04-9, 123-22-8

Diethyl phosphonate

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
triethylamine Ambient temperature;85.5%
With triethylamine at 90℃; for 12h;60%
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane; water for 1h; Ambient temperature;53%
With triethylamine In toluene at 70℃; for 2h;
N-methoxypyridinium p-toluenesulfonate
53920-49-3

N-methoxypyridinium p-toluenesulfonate

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

diethyl pyridin-2-yl-2-phosphonate
23081-78-9

diethyl pyridin-2-yl-2-phosphonate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile for 0.0833333h;A 20%
B 74%
Diethyl phosphonate
762-04-9, 123-22-8

Diethyl phosphonate

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
With nitrogen; triethylamine; paraformaldehyde60%
With nitrogen; triethylamine; paraformaldehyde60%
With triethylamine; paraformaldehyde57.5 g (68%)
formaldehyd
50-00-0

formaldehyd

4-methoxy-aniline
104-94-9

4-methoxy-aniline

triethyl phosphite
122-52-1

triethyl phosphite

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

diethyl ester of p-N-methoxyphenylaminomethylphosphonic acid
81439-58-9

diethyl ester of p-N-methoxyphenylaminomethylphosphonic acid

C

1,3,5-tris-(4-methoxybenzyl)-1,3,5-triazinane

1,3,5-tris-(4-methoxybenzyl)-1,3,5-triazinane

Conditions
ConditionsYield
In xylene at 120℃; for 1h;A 16%
B 55%
C 5.5%
trioxa-4,10,16-triaza-1,7,13-cyclooctadecane
296-38-8

trioxa-4,10,16-triaza-1,7,13-cyclooctadecane

formaldehyd
50-00-0

formaldehyd

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

[10,16-bis-(diethoxy-phosphorylmethyl)-1,7,13-trioxa-4,10,16-triaza-cyclooctadec-4-ylmethyl]-phosphonic acid diethyl ester

[10,16-bis-(diethoxy-phosphorylmethyl)-1,7,13-trioxa-4,10,16-triaza-cyclooctadec-4-ylmethyl]-phosphonic acid diethyl ester

Conditions
ConditionsYield
With triethylamine In benzene Alkylation; Mannich reaction; substitution; Heating;A n/a
B 37%
formaldehyd
50-00-0

formaldehyd

p-aminoethylbenzoate
94-09-7

p-aminoethylbenzoate

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

p-N,N-diethylaminobenzoic acid ethyl ester
10287-54-4

p-N,N-diethylaminobenzoic acid ethyl ester

C

diethyl 4,4′-(methylenebis(azanediyl))dibenzoate
74763-68-1

diethyl 4,4′-(methylenebis(azanediyl))dibenzoate

D

Diethyl (p-ethoxycarbonylphenylaminomethyl)phosphonate
114416-19-2

Diethyl (p-ethoxycarbonylphenylaminomethyl)phosphonate

Conditions
ConditionsYield
With triethyl phosphite In toluene at 110 - 120℃; for 6.5h;A 32.8%
B n/a
C 24.4%
D 23.8%
formaldehyd
50-00-0

formaldehyd

p-aminoethylbenzoate
94-09-7

p-aminoethylbenzoate

triethyl phosphite
122-52-1

triethyl phosphite

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

p-N,N-diethylaminobenzoic acid ethyl ester
10287-54-4

p-N,N-diethylaminobenzoic acid ethyl ester

C

diethyl 4,4′-(methylenebis(azanediyl))dibenzoate
74763-68-1

diethyl 4,4′-(methylenebis(azanediyl))dibenzoate

D

Diethyl (p-ethoxycarbonylphenylaminomethyl)phosphonate
114416-19-2

Diethyl (p-ethoxycarbonylphenylaminomethyl)phosphonate

Conditions
ConditionsYield
In toluene at 110 - 120℃; for 6.5h;A 32.8%
B n/a
C 24.4%
D 23.8%
formaldehyd
50-00-0

formaldehyd

triethyl phosphite
122-52-1

triethyl phosphite

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
With 2-methoxy-phenylamine
trioxa-4,10,16-triaza-1,7,13-cyclooctadecane
296-38-8

trioxa-4,10,16-triaza-1,7,13-cyclooctadecane

formaldehyd
50-00-0

formaldehyd

triethyl phosphite
122-52-1

triethyl phosphite

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

[10,16-bis-(diethoxy-phosphorylmethyl)-1,7,13-trioxa-4,10,16-triaza-cyclooctadec-4-ylmethyl]-phosphonic acid diethyl ester

[10,16-bis-(diethoxy-phosphorylmethyl)-1,7,13-trioxa-4,10,16-triaza-cyclooctadec-4-ylmethyl]-phosphonic acid diethyl ester

Conditions
ConditionsYield
Alkylation; Arbuzov reaction; substitution;
diiodomethane
75-11-6

diiodomethane

potassium salt of phosphoric acid diethyl ester

potassium salt of phosphoric acid diethyl ester

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
With ethanol (90 percent )
diiodomethane
75-11-6

diiodomethane

ethanol
64-17-5

ethanol

potassium salt of phosphorous acid diethyl ester

potassium salt of phosphorous acid diethyl ester

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

formaldehyd
50-00-0

formaldehyd

bis(phthalimidylethyl)amine
63563-83-7

bis(phthalimidylethyl)amine

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

({bis-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-amino}-methyl)-phosphonic acid diethyl ester

({bis-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-amino}-methyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
In ethanol; toluene for 12h; Heating; Title compound not separated from byproducts.;
paraformaldehyde powder

paraformaldehyde powder

Diethyl phosphonate
762-04-9, 123-22-8

Diethyl phosphonate

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Conditions
ConditionsYield
With triethylamine
N-ethyl-N,N-diisopropylamine
1,2-dimethoxyethane
110-71-4

1,2-dimethoxyethane

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

B

diethyl 1-hydroxy-2-methoxyethylphosphonate
19462-41-0

diethyl 1-hydroxy-2-methoxyethylphosphonate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; potassium carbonate; copper dichloride In decane at 80℃; for 24h; Inert atmosphere; Overall yield = 53 %; Overall yield = 72 %Spectr.;
2-ethoxy-2,3-dihydro-4H-pyran
103-75-3

2-ethoxy-2,3-dihydro-4H-pyran

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

(6-Ethoxy-tetrahydro-pyran-2-yloxymethyl)-phosphonic acid diethyl ester

(6-Ethoxy-tetrahydro-pyran-2-yloxymethyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With hydrogenchloride98.3%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

(diethoxyphosphinyl)methyl trifluoromethanesulfonate
106938-62-9

(diethoxyphosphinyl)methyl trifluoromethanesulfonate

Conditions
ConditionsYield
With 2,6-dimethylpyridine In dichloromethane98%
Stage #1: diethyl (1-hydroxymethyl)phosphonate With 2,6-dimethylpyridine In dichloromethane at -50℃; for 0.0833333h; Inert atmosphere;
Stage #2: trifluoromethylsulfonic anhydride In dichloromethane at -50℃; for 0.333333h;
92.4%
With pyridine In dichloromethane at -78℃; for 3h;90%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

diethyl (p-toluenesulfonyloxymethane)phosphonate
31618-90-3

diethyl (p-toluenesulfonyloxymethane)phosphonate

Conditions
ConditionsYield
With triethylamine In diethyl ether97%
In water at 3 - 35℃; for 14.5h; Temperature;95.4%
With triethylamine In dichloromethane at 20℃; for 4h; Inert atmosphere;92%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

ethyl lithium hydroxymethylphosphonate

ethyl lithium hydroxymethylphosphonate

Conditions
ConditionsYield
With lithium bromide In various solvent(s) at 80℃; for 0.5h;97%
2-butoxy-(2H)-3,4-dihydropyran
332-19-4

2-butoxy-(2H)-3,4-dihydropyran

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

(6-Butoxy-tetrahydro-pyran-2-yloxymethyl)-phosphonic acid diethyl ester

(6-Butoxy-tetrahydro-pyran-2-yloxymethyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With hydrogenchloride96.9%
2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one
5381-99-7

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

(4-Oxo-4H-benzo[1,3,2]dioxaphosphinin-2-yloxymethyl)-phosphonic acid diethyl ester
140383-34-2

(4-Oxo-4H-benzo[1,3,2]dioxaphosphinin-2-yloxymethyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With triethylamine In diethyl ether for 2h;95%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

diethyl (4-methyl-2-oxa-4-pentenyl)phosphonate
108070-91-3

diethyl (4-methyl-2-oxa-4-pentenyl)phosphonate

Conditions
ConditionsYield
Stage #1: diethyl (1-hydroxymethyl)phosphonate With sodium hydride In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 3-Chloro-2-methylpropene In tetrahydrofuran for 1h;
95%
2-methylprop-1-enyl chloride
513-37-1

2-methylprop-1-enyl chloride

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

diethyl (4-methyl-2-oxa-4-pentenyl)phosphonate
108070-91-3

diethyl (4-methyl-2-oxa-4-pentenyl)phosphonate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 1h;95%
aminoethylpiperazine
140-31-8

aminoethylpiperazine

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

C11H26N3O3P

C11H26N3O3P

Conditions
ConditionsYield
at 0 - 40℃; for 1h;95%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

zinc(II) acetate dihydrate
5970-45-6

zinc(II) acetate dihydrate

Zn(2+)*HOCH2PO3(2-)=Zn(O3PCH2OH)

Zn(2+)*HOCH2PO3(2-)=Zn(O3PCH2OH)

Conditions
ConditionsYield
In water to soln. Zn(OAc)2*2H2O in water was added HOCH2P(O)(OEt)2, mixt. was stirred for 30 min, transfeed into autoclave and heated at 160°C for48 h; solid was filtered and washed with water; elem. anal.;94%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

diethyl <<(2-tetrahydropyranyl)oxy>methyl>phosphonate
71885-51-3

diethyl <<(2-tetrahydropyranyl)oxy>methyl>phosphonate

Conditions
ConditionsYield
With trichlorophosphate In diethyl ether at 20℃; for 3h;93%
With hydrogenchloride90.6%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

(2'R)-1-(2,3-dihydrofuran-2-yl)thymine
37076-62-3

(2'R)-1-(2,3-dihydrofuran-2-yl)thymine

(2'R,3'S,5'R)-1-(2-diethoxyphosphinoylmethoxy-3-iodotetrahydrofuran-5-yl)thymine

(2'R,3'S,5'R)-1-(2-diethoxyphosphinoylmethoxy-3-iodotetrahydrofuran-5-yl)thymine

Conditions
ConditionsYield
With iodine(I) bromide In dichloromethane at -25℃; for 0.833333h;92%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

Methacryloyl chloride
920-46-7

Methacryloyl chloride

Methacrylsaeure-diaethoxy-phosphinylmethylester
60161-88-8

Methacrylsaeure-diaethoxy-phosphinylmethylester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;91%
With triethylamine; copper(l) chloride
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

A

magnesium para-toluenesulfonate

magnesium para-toluenesulfonate

B

diethyl (p-toluenesulfonyloxymethane)phosphonate
31618-90-3

diethyl (p-toluenesulfonyloxymethane)phosphonate

Conditions
ConditionsYield
With magnesium carbonate In water at 65℃; for 20h;A n/a
B 91%
N-hydroxyphthalimide
524-38-9

N-hydroxyphthalimide

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

diethyl (N-phthalimidyl)oxymethylphosphonate
81342-57-6

diethyl (N-phthalimidyl)oxymethylphosphonate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0℃; for 1h;90%
With diethyl azodicarbonate; triphenylphosphine In tetrahydrofuran Ambient temperature;70.2%
With triphenylphosphine; diethylazodicarboxylate
pyrocatechol phosphorochloridite
1641-40-3

pyrocatechol phosphorochloridite

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

2-(α-diethoxyphosphinoylmethoxy)-4,5-benzo-1,3,2-dioxaphospholane

2-(α-diethoxyphosphinoylmethoxy)-4,5-benzo-1,3,2-dioxaphospholane

Conditions
ConditionsYield
With triethylamine In benzene at 5 - 10℃;90%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

diethyl <<(methylsulfonyl)oxy>methyl>phosphonate
114108-84-8

diethyl <<(methylsulfonyl)oxy>methyl>phosphonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at -10 - 20℃; for 2h;90%
With triethylamine In toluene at 0 - 20℃;89%
With triethylamine In dichloromethane at 0 - 20℃;80%
2,3-dihydro-2H-furan
1191-99-7

2,3-dihydro-2H-furan

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

O,O-diethyl(2-tetrahydrofuranyloxy)methyl phosphonate
79872-66-5

O,O-diethyl(2-tetrahydrofuranyloxy)methyl phosphonate

Conditions
ConditionsYield
With hydrogenchloride88.9%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

3-nitrobenzoic acid
121-92-6

3-nitrobenzoic acid

(diethoxyphosphoryl)methyl 3-nitrobenzoate

(diethoxyphosphoryl)methyl 3-nitrobenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 18h;87.1%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

diethyl (azidomethyl)phosphonate
17982-55-7

diethyl (azidomethyl)phosphonate

Conditions
ConditionsYield
With tris-(2-chloro-ethyl)-amine; triphenylphosphine; diethylazodicarboxylate In dichloromethane; benzene 0 deg C, 30 min to r.t., 20 h;87%
With ammonia; triphenylphosphine; diethylazodicarboxylate In dichloromethane for 20h;
With tris-(2-chloro-ethyl)-amine; triphenylphosphine; diethylazodicarboxylate In dichloromethane for 20h;
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

diethyl chloromethylphosphonate
3167-63-3

diethyl chloromethylphosphonate

Conditions
ConditionsYield
With tetrachloromethane; triphenylphosphine for 8h; Heating;86%
With tetrachloromethane; triphenylphosphine Appel reaction;77%
With thionyl chloride In benzene
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

diethyl (4-nitrobenzenesulfonyloxy)methylphosphonate
294202-81-6

diethyl (4-nitrobenzenesulfonyloxy)methylphosphonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;85%
With triethylamine In dichloromethane at 0 - 25℃;
6-methoxybenzofuran-2-carboxylic acid
50551-61-6

6-methoxybenzofuran-2-carboxylic acid

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

(diethoxyphosphoryl)methyl 6-methoxybenzofuran-2-carboxylate

(diethoxyphosphoryl)methyl 6-methoxybenzofuran-2-carboxylate

Conditions
ConditionsYield
Stage #1: 6-methoxybenzofuran-2-carboxylic acid With diisopropyl-carbodiimide In dichloromethane at 20℃; for 1h;
Stage #2: diethyl (1-hydroxymethyl)phosphonate With dmap In dichloromethane for 6h; Reflux;
85%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

1,2-O-isopropylidene-5-methyl-5-deoxy-α-D-xylofuranose
4152-79-8, 33156-02-4, 37105-87-6, 37105-91-2, 37105-93-4, 53597-97-0, 97059-40-0

1,2-O-isopropylidene-5-methyl-5-deoxy-α-D-xylofuranose

5-deoxy-3-O-(diethylphosphonomethyl)-1,2-O-isopropylidenyl-D-xylose

5-deoxy-3-O-(diethylphosphonomethyl)-1,2-O-isopropylidenyl-D-xylose

Conditions
ConditionsYield
With sodium hydride In mineral oil at 0 - 20℃; for 6h; Inert atmosphere;83%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

ortho-nitrobenzoic acid
552-16-9

ortho-nitrobenzoic acid

(diethoxyphosphoryl)methyl 2-nitrobenzoate

(diethoxyphosphoryl)methyl 2-nitrobenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 18h;82.8%
diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

5,6-dimethoxyindole-2-carboxylic acid
88210-96-2

5,6-dimethoxyindole-2-carboxylic acid

C16H22NO7P

C16H22NO7P

Conditions
ConditionsYield
Stage #1: 5,6-dimethoxyindole-2-carboxylic acid With diisopropyl-carbodiimide In dichloromethane at 20℃; for 1h;
Stage #2: diethyl (1-hydroxymethyl)phosphonate With dmap In dichloromethane for 6h; Reflux;
82%
6-methoxy-1-benzothiophene-2-carboxylic acid
102539-79-7

6-methoxy-1-benzothiophene-2-carboxylic acid

diethyl (1-hydroxymethyl)phosphonate
3084-40-0

diethyl (1-hydroxymethyl)phosphonate

(diethoxyphosphoryl)methyl 6-methoxybenzothiophene-2-carboxylate

(diethoxyphosphoryl)methyl 6-methoxybenzothiophene-2-carboxylate

Conditions
ConditionsYield
Stage #1: 6-methoxybenzo[b]thiophene-2-carboxylic acid With diisopropyl-carbodiimide In dichloromethane at 20℃; for 1h;
Stage #2: diethyl (1-hydroxymethyl)phosphonate With dmap In dichloromethane for 5h; Reflux;
81%

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