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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Manufacturer 1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1,2,4-Trifluorobenzene Manufacturer/High quality/Best price/In stock

Cas:367-23-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1,2,4-Trifluorobenzene supplier in China

Cas:367-23-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 1.2.4-TRIFLUOROBENZENE CAS No. 367-23-7 Appearance

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

367-23-7 1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 367-23-7 1,2,4-Trifluorobenzene Manufacturer

Cas:367-23-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Product Name: 1,2,4-Trifluorobenzene Synonyms: 1,2,4-TRIFLUOROBENZENE;1,3,4-Trifluorobenzene;Benzene, 1,2,4-trifluoro-;Trifluorobenzene2;1,2,4-Trifluorobenzene, 97+%;1,2,4-Trifluorobenzene,98+%;1,2,4-Trifluorobenzene 99%;1,2,4-Trifluor

367-23-7 1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1, 2, 4-Trifluorobenzene CAS 367-23-7

Cas:367-23-7

Min.Order:1 Gram

FOB Price: $6.0 / 9.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 367-23-7 with fast shipping

Cas:367-23-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material 1,2,4-Trifluorobenzene CAS 367-23-7

Cas:367-23-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: 1,2,4-Trifluorobenzene Synonyms: 1,2,4-TRIFLUOROBENZENE;1,3,4-Trifluorobenzene;Benzene, 1,2,4-trifluoro-;1,2,4-TrifL;3-(2-cyclohexylideneethyl)-4-hydroxynaphthalene-1,2-dione;Trifluorobenzene2

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Factory supply and best quality 1,2,4-Trifluorobenzene CAS 367-23-7

Cas:367-23-7

Min.Order:100 Gram

Negotiable

Type:Other

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 367-23-7 1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:367-23-7

Cas:367-23-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Name: 1, 2, 4-Trifluorobenzene CAS NO.: 367-23-7 Structural formula: Appearance: colorless clear liquid, boiling point: 89~90°C Content:

1,2,4-Trifluorobenzene manufacture

Cas:367-23-7

Min.Order:50 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1,2,4-TRIFLUOROBENZENE

Cas:367-23-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging

1,2,4-Trifluorobenzene

Cas:367-23-7

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D

Manufacturer 1,2,4-Trifluorobenzene CAS NO.367-23-7

Cas:367-23-7

Min.Order:10 Gram

FOB Price: $5.0 / 7.0

Type:Trading Company

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1,2,4-Trifluorobenzene/High quality/Best price

Cas:367-23-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

2,4-dinitro-1-fluorobenzene
7800-26-2

2,4-dinitro-1-fluorobenzene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In dimethyl sulfoxide at 25℃; for 0.166667h; Inert atmosphere; Microwave irradiation; Anhydrous conditions;95%
2,4,5-trifluorobenzoic acid
446-17-3

2,4,5-trifluorobenzoic acid

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With ammonia; copper In water at 260℃; for 1.25h; Temperature; Reagent/catalyst;94.9%
In quinoline
1,2,3,4-tetrafluorobenzene
551-62-2

1,2,3,4-tetrafluorobenzene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With [(bis(diisopropylphosphino)ethane)Ni(H)]2; triethylphosphine In 1,4-dioxane at 120℃; for 72h;94%
With C32H46N2Ru; sodium carbonate; isopropyl alcohol at 70℃; for 6h; Inert atmosphere; Schlenk technique; Glovebox;63%
With (1,3-dimethylimidazolin-2-ylidene)*AlH3 In 5,5-dimethyl-1,3-cyclohexadiene at 135℃; for 25h;19%
2,4,5-trifluorobenzaldehyde
165047-24-5

2,4,5-trifluorobenzaldehyde

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With triethylsilane; C18H51CoP4Si In tetrahydrofuran at 50℃; for 6h; Inert atmosphere;94%
2,3,5,6-tetrafluorothiophenol
769-40-4

2,3,5,6-tetrafluorothiophenol

A

1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene
651-80-9

1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene

B

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With water; triethylphosphine In 1,4-dioxane at 120℃; for 4h; Schlenk technique; Inert atmosphere; Glovebox;A 90%
B 10%
C6H3FN4(2+)*2BF4(1-)

C6H3FN4(2+)*2BF4(1-)

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
In diethyl ether at 120 - 180℃; for 6h;82%
2,4-difluorophenylamine
367-25-9

2,4-difluorophenylamine

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
Stage #1: 2,4-difluorophenylamine With sodium tetrafluoroborate; nitrosylsulfuric acid; acetic acid at -5 - 20℃;
Stage #2: at 250℃; Inert atmosphere;
80%
Stage #1: 2,4-difluorophenylamine With hydrogenchloride; fluoroboric acid; sodium nitrite In water at 25℃; for 0.00555556h; Balz-Schiemann Reaction;
Stage #2: In 1,2-dichloro-benzene at 200℃; for 0.0166667h; Balz-Schiemann Reaction;
72%
1,2,4-Trichlorobenzene
120-82-1

1,2,4-Trichlorobenzene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With potassium fluoride; C6H11BO3 In sulfolane (tetramethylene sulfone) at 245℃; for 3h; Inert atmosphere;78%
Hexafluorobenzene
392-56-3

Hexafluorobenzene

A

1,2,4,5-Tetrafluorobenzene
327-54-8

1,2,4,5-Tetrafluorobenzene

B

1,2,3,4-tetrafluorobenzene
551-62-2

1,2,3,4-tetrafluorobenzene

C

Pentafluorobenzene
363-72-4

Pentafluorobenzene

D

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With (1,3-dimethylimidazolin-2-ylidene)*AlH3 In 5,5-dimethyl-1,3-cyclohexadiene at 135℃; for 25h;A 74%
B 3%
C 18%
D 4%
Pentafluorobenzene
363-72-4

Pentafluorobenzene

A

para-difluorobenzene
540-36-3

para-difluorobenzene

B

1,2,4,5-Tetrafluorobenzene
327-54-8

1,2,4,5-Tetrafluorobenzene

C

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With C32H46N2Ru; sodium carbonate; isopropyl alcohol at 70℃; for 4h; Inert atmosphere; Schlenk technique; Glovebox;A 7%
B 60%
C 21%
2,4-difluorophenyldiazonium tetrafluoroborate

2,4-difluorophenyldiazonium tetrafluoroborate

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
at 185℃; for 1h; Decomposition;52%
Pyrolysis;
1,2,4,5-Tetrafluorobenzene
327-54-8

1,2,4,5-Tetrafluorobenzene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With C32H46N2Ru; sodium carbonate; isopropyl alcohol at 70℃; for 6h; Inert atmosphere; Schlenk technique; Glovebox;48%
With H2SiEt2; tetrabutylammonium triphenyldifluorosilicate In tetrahydrofuran; benzene-d6 at 100℃; for 40h; Inert atmosphere; Sealed tube;18%
1,2,4,5-Tetrafluorobenzene
327-54-8

1,2,4,5-Tetrafluorobenzene

A

para-difluorobenzene
540-36-3

para-difluorobenzene

B

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
Stage #1: 1,2,4,5-Tetrafluorobenzene With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; [(HC[(CMe)N(2,4,6-Me3C6H2)]2)Al(H)2] In benzene-d6; benzene at 100℃; for 8h; Inert atmosphere; Glovebox; Sealed tube;
Stage #2: With methanol In benzene-d6; benzene at 100℃; for 2h; Catalytic behavior; Inert atmosphere; Glovebox; Sealed tube; regioselective reaction;
A 19.5%
B 47%
1,2,3,5-tetrafluorobenzene
2367-82-0

1,2,3,5-tetrafluorobenzene

A

1,2,3-trifluorobenzene
1489-53-8

1,2,3-trifluorobenzene

B

1,3-Difluorobenzene
372-18-9

1,3-Difluorobenzene

C

para-difluorobenzene
540-36-3

para-difluorobenzene

D

ortho-difluorobenzene
367-11-3

ortho-difluorobenzene

E

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
Stage #1: 1,2,3,5-tetrafluorobenzene With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; [(HC[(CMe)N(2,4,6-Me3C6H2)]2)Al(H)2] In benzene-d6; benzene at 100℃; for 8h; Inert atmosphere; Glovebox; Sealed tube;
Stage #2: With methanol In benzene-d6; benzene at 100℃; for 2h; Catalytic behavior; Inert atmosphere; Glovebox; Sealed tube; Overall yield = 69.5 %; regioselective reaction;
A 8.5%
B 9.5%
C 7%
D 5.5%
E 39%
ortho-difluorobenzene
367-11-3

ortho-difluorobenzene

A

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

B

5,5,6,6-tetrafluoro-1,3-cyclohexadiene
74298-22-9

5,5,6,6-tetrafluoro-1,3-cyclohexadiene

C

2,3,3,6-tetrafluoro-1,4-cyclohexadiene
74298-21-8

2,3,3,6-tetrafluoro-1,4-cyclohexadiene

Conditions
ConditionsYield
With silver(II) fluoride In hexane for 2h; Product distribution; Heating;A 3%
B 15.7%
C 28%
With silver(II) fluoride In hexane for 2h; Heating;A 3%
B 15.7%
C 28%
fluoroethyne
2713-09-9

fluoroethyne

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
Raumtemperatur;
at 20℃;
para-difluorobenzene
540-36-3

para-difluorobenzene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
durch Nitrierung, Reduktion, Diazotierung und Zersetzung des entsprechenden Diazoniumbortetrafluorids durch Erhitzen;
2,5-difluorobenzenediazonium tetrafluoroborate

2,5-difluorobenzenediazonium tetrafluoroborate

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
Pyrolysis;
p-benzoquinone
106-51-4

p-benzoquinone

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With sulfur tetrafluoride; hydrogen fluoride at 200℃;
2,3,5-Trifluorbicyclo<2.2.0>hexa-3,5-dien

2,3,5-Trifluorbicyclo<2.2.0>hexa-3,5-dien

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With (thermolysis) at 79.9℃; Rate constant;
1,2,5-Trifluorbicyclo<2.2.0>hexa-2,5-dien

1,2,5-Trifluorbicyclo<2.2.0>hexa-2,5-dien

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With (thermolysis) at 79.9℃; Rate constant;
1,2,5-trifluorobicyclo<2.2.0>hexa-2,5-diene
31399-10-7

1,2,5-trifluorobicyclo<2.2.0>hexa-2,5-diene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
at 79.9℃; Rate constant; gas-phase thermal isomerization;
5-chloro-1,2,4-trifluorobenzene
2367-78-4

5-chloro-1,2,4-trifluorobenzene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol Heating;
palladium-carbon
hexafluoro-1,3-butadiene
685-63-2

hexafluoro-1,3-butadiene

buta-1,3-diene
106-99-0

buta-1,3-diene

A

1,2,3-trifluorobenzene
1489-53-8

1,2,3-trifluorobenzene

B

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With pyrographite; hydroquinone 1. heating, 2. pyrolysis; Multistep reaction;
hexafluoro-1,3-butadiene
685-63-2

hexafluoro-1,3-butadiene

buta-1,3-diene
106-99-0

buta-1,3-diene

A

1,2,3-trifluorobenzene
1489-53-8

1,2,3-trifluorobenzene

B

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

C

1,2,2,5,6,6-hexafluorotricyclo<3.3.0.06,8>octane
92818-42-3

1,2,2,5,6,6-hexafluorotricyclo<3.3.0.06,8>octane

Conditions
ConditionsYield
With pyrographite; hydroquinone 1. heating, 2. pyrolysis; Multistep reaction;
benzene
71-43-2

benzene

A

fluorobenzene
462-06-6

fluorobenzene

B

para-difluorobenzene
540-36-3

para-difluorobenzene

C

ortho-difluorobenzene
367-11-3

ortho-difluorobenzene

D

1,2,4,5-Tetrafluorobenzene
327-54-8

1,2,4,5-Tetrafluorobenzene

E

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With tetrafluoroammonium tetrafluoroborate In hydrogen fluoride at 0℃; Product distribution; NF4BF4 to benzene ratio;A 33 % Spectr.
B 27 % Spectr.
C 7 % Spectr.
D 15 % Spectr.
E 18 % Spectr.
benzene
71-43-2

benzene

A

fluorobenzene
462-06-6

fluorobenzene

B

para-difluorobenzene
540-36-3

para-difluorobenzene

C

ortho-difluorobenzene
367-11-3

ortho-difluorobenzene

D

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With tetrafluoroammonium tetrafluoroborate In hydrogen fluoride at 0℃; Further byproducts given. Title compound not separated from byproducts;A 33 % Spectr.
B 27 % Spectr.
C 7 % Spectr.
D 18 % Spectr.
C6H4F3(1+)

C6H4F3(1+)

benzene
71-43-2

benzene

A

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
at 26.9℃; Rate constant; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.);
1,3-Difluorobenzene
372-18-9

1,3-Difluorobenzene

A

1,2,4,5-Tetrafluorobenzene
327-54-8

1,2,4,5-Tetrafluorobenzene

B

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; fluorine In trichlorofluoromethane at -15℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
para-difluorobenzene
540-36-3

para-difluorobenzene

A

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

B

2,5-difluorophenol
2713-31-7

2,5-difluorophenol

C

4H/5H-3,3,4,5,6,6-Hexafluor-cyclohexen
703-16-2

4H/5H-3,3,4,5,6,6-Hexafluor-cyclohexen

D

3,3,6,6-tetrafluoro-1,4-cyclohexadiene
22060-77-1

3,3,6,6-tetrafluoro-1,4-cyclohexadiene

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; fluorine In trichlorofluoromethane at -25℃; for 3h; Further byproducts given. Title compound not separated from byproducts;
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1,2,4-trifluoro-3-nitrobenzene
42096-74-2

1,2,4-trifluoro-3-nitrobenzene

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 50℃; for 4h; Temperature;99.2%
sodium cyanide
773837-37-9

sodium cyanide

dichloromethane
75-09-2

dichloromethane

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

(2,4,5-trifluorophenyl)acetic acid
209995-38-0

(2,4,5-trifluorophenyl)acetic acid

Conditions
ConditionsYield
Stage #1: sodium cyanide With sodium stearate; nitrobenzene; sodium hydroxide In water at 115℃; under 3420.23 Torr; for 0.75h; Inert atmosphere;
Stage #2: dichloromethane; 1,2,4-trifluorobenzene at 6 - 142℃; under 2280.15 - 5320.36 Torr; for 6h; Solvent; Pressure; Reagent/catalyst; Further stages;
99.2%
(tri-tert-butylphosphane)gold(I) chloride
69550-28-3

(tri-tert-butylphosphane)gold(I) chloride

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

((CH3)3C)3PAuC6H2F3
1224321-78-1

((CH3)3C)3PAuC6H2F3

Conditions
ConditionsYield
With Ag2O; K2CO3; pivalic acid In dimethylformamide react. gold complex with arene in DMF at 50°C for 2 h in the presence of Ag2O, K2CO3 and pivalic acid;99%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1-bromo-2,4,5-trifluorobenzene
327-52-6

1-bromo-2,4,5-trifluorobenzene

Conditions
ConditionsYield
With bromine; acetic acid at 20℃; for 2h; Reagent/catalyst; Temperature;98.7%
With bromine; iron Reagent/catalyst; Inert atmosphere;92%
With bromine; iron
potassium cyanide

potassium cyanide

dichloromethane
75-09-2

dichloromethane

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

(2,4,5-trifluorophenyl)acetic acid
209995-38-0

(2,4,5-trifluorophenyl)acetic acid

Conditions
ConditionsYield
Stage #1: potassium cyanide With sodium stearate; nitrobenzene; potassium hydroxide In water at 100℃; under 2280.15 Torr; for 0.5h; Inert atmosphere;
Stage #2: dichloromethane; 1,2,4-trifluorobenzene at 6 - 130℃; under 2280.15 - 3800.26 Torr; Further stages;
98.2%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

dimethylglyoxal
431-03-8

dimethylglyoxal

3-hydroxy-3-(2,3,6-trifluorophenyl)butan-2-one

3-hydroxy-3-(2,3,6-trifluorophenyl)butan-2-one

Conditions
ConditionsYield
Stage #1: 1,2,4-trifluorobenzene With n-butyllithium; diisopropylamine In tetrahydrofuran at -70 - -40℃; for 0.5h;
Stage #2: dimethylglyoxal In tetrahydrofuran at -70 - -45℃; for 1h;
Stage #3: With water; acetic acid In tetrahydrofuran
98%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2,4,5-trifluoro-α-chloroacetophenone
129604-31-5

2,4,5-trifluoro-α-chloroacetophenone

Conditions
ConditionsYield
With aluminium trichloride Acylation;95%
With aluminum (III) chloride at 70℃; for 16h;93%
aluminium chloride In ice-water; dichloromethane
4-ethylpiperazine
5308-25-8

4-ethylpiperazine

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1,2,4-triazolo<4,3-a>pyridin-3-thiol
6952-68-7

1,2,4-triazolo<4,3-a>pyridin-3-thiol

3-((2-(4-(2,4-difluorophenyl)-piperazin-1-yl)ethyl)thio)-[1,2,4]triazolo[4,3-a]pyridine

3-((2-(4-(2,4-difluorophenyl)-piperazin-1-yl)ethyl)thio)-[1,2,4]triazolo[4,3-a]pyridine

Conditions
ConditionsYield
With sodium sulfide; lithium hydroxide In N,N-dimethyl-formamide at 80℃; for 12h;95%
methyl-4-bromo-2-butenoate
1117-71-1, 56699-18-4, 6000-00-6

methyl-4-bromo-2-butenoate

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

(E)-4-(2,4,5-trifluoro-phenyl)-but-2-enoic acid methyl ester
1260029-44-4

(E)-4-(2,4,5-trifluoro-phenyl)-but-2-enoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 1,2,4-trifluorobenzene With isopropylmagnesium chloride In tetrahydrofuran at -20 - -10℃; for 1h; Inert atmosphere;
Stage #2: methyl-4-bromo-2-butenoate With N,N,N,N,-tetramethylethylenediamine; cobalt(II) bromide In tetrahydrofuran at -20 - 0℃; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; water
93%
(triphenylphosphine)gold(I) chloride
14243-64-2

(triphenylphosphine)gold(I) chloride

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

2,3,6-trifluorophenyl(triphenylphosphine)gold(I)

2,3,6-trifluorophenyl(triphenylphosphine)gold(I)

Conditions
ConditionsYield
With potassium carbonate; silver(l) oxide; Trimethylacetic acid In N,N-dimethyl-formamide at 50℃; for 16h; Inert atmosphere;92%
2-naphthyl triflate
3857-83-8

2-naphthyl triflate

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

2-(1',3',4'-trifluorophenyl)naphthalene

2-(1',3',4'-trifluorophenyl)naphthalene

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); 18-crown-6 ether; 2-[bis((3,5-dimethyl-4-methoxyphenyl)phosphino)phenyl]ether; isopropylmagnesium chloride In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane at 40℃; for 2h;91%
glycolide
502-97-6

glycolide

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

(2,4,5-trifluorophenyl)acetic acid
209995-38-0

(2,4,5-trifluorophenyl)acetic acid

Conditions
ConditionsYield
With aluminum (III) chloride at 70℃; for 12h;90.4%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

3-hydroxy-3-(2,3,6-trifluorophenyl)butan-2-one

3-hydroxy-3-(2,3,6-trifluorophenyl)butan-2-one

Conditions
ConditionsYield
With n-butyllithium; diisopropylamine In tetrahydrofuran at -70 - -45℃; for 0.5h;90.2%
carbon dioxide
124-38-9

carbon dioxide

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

2,3,6-trifluorobenzoic acid
2358-29-4

2,3,6-trifluorobenzoic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide With AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); potassium hydroxide In tetrahydrofuran at 20℃; under 1125.11 Torr; for 0.25h;
Stage #2: 1,2,4-trifluorobenzene In tetrahydrofuran at 20℃; under 1125.11 Torr; for 12h;
Stage #3: With hydrogenchloride In tetrahydrofuran; water regioselective reaction;
88%
Stage #1: carbon dioxide; 1,2,4-trifluorobenzene With cesium hydroxide; (hydroxido){N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene}copper(I) In tetrahydrofuran at 65℃; for 8h; Inert atmosphere;
Stage #2: With hydrogenchloride In water Inert atmosphere; regioselective reaction;
85%
Stage #1: 1,2,4-trifluorobenzene With n-butyllithium In tetrahydrofuran at -70℃; Metallation;
Stage #2: carbon dioxide In tetrahydrofuran Carboxylation;
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

4-methoxyphenylacetylen
768-60-5

4-methoxyphenylacetylen

1,2-difluoro-4-((4-methoxyphenyl)ethynyl)benzene
854266-72-1

1,2-difluoro-4-((4-methoxyphenyl)ethynyl)benzene

Conditions
ConditionsYield
With butyl magnesium bromide; sodium methylate; sodium; calcium hydroxide In tetrahydrofuran at 0℃; for 0.0916667h; Sonogashira Cross-Coupling; Inert atmosphere; Reflux;88%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

acetyl chloride
75-36-5

acetyl chloride

2',4',5'-trifluoroacetophenone
129322-83-4

2',4',5'-trifluoroacetophenone

Conditions
ConditionsYield
With aluminium trichloride at 80℃; for 24h; Acylation;87%
With aluminium trichloride 1.) 50 deg C, 1 h, 2.) 80 deg C, 22 h; Yield given. Multistep reaction;
Acetylation;
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
582-52-5

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

1,2:5,6-di-O-isopropylidene-3-O-(2',5'-difluoro)benzene-α-D-glucofuranoside

1,2:5,6-di-O-isopropylidene-3-O-(2',5'-difluoro)benzene-α-D-glucofuranoside

Conditions
ConditionsYield
With potassium hexamethylsilazane In N,N-dimethyl-formamide; toluene at 0 - 20℃; for 16h; Inert atmosphere; Schlenk technique; regioselective reaction;86%
indole
120-72-9

indole

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1-(2,5-difluorophenyl)-1H-indole
1448804-18-9

1-(2,5-difluorophenyl)-1H-indole

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl-formamide at 70℃; Sealed tube; Schlenk technique; Inert atmosphere;85%
dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

2,4,5-trifluoromandelic acid
375369-29-2

2,4,5-trifluoromandelic acid

Conditions
ConditionsYield
Stage #1: dichloroacethyl chloride; 1,2,4-trifluorobenzene; aluminum (III) chloride at 60℃;
Stage #2: With sodium hydroxide; water at 60℃;
Stage #3: With hydrogenchloride In water at 0 - 20℃; pH=1;
84%
2-methyl-3-bromo-1-propene
1458-98-6

2-methyl-3-bromo-1-propene

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1,2,4-trifluoro-3-(2-methylprop-1-en-1-yl)benzene

1,2,4-trifluoro-3-(2-methylprop-1-en-1-yl)benzene

Conditions
ConditionsYield
With [Cu(1,3-di-iso-propylimidazolin-2-ylidene)(Cl)]; sodium t-butanolate In tetrahydrofuran at 60℃; for 12h; Inert atmosphere; Schlenk technique; Glovebox;84%
3-Bromopyridine
626-55-1

3-Bromopyridine

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

3-(2,3,6-trifluorophenyl)pyridine

3-(2,3,6-trifluorophenyl)pyridine

Conditions
ConditionsYield
With palladium 10% on activated carbon; potassium acetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; regioselective reaction;84%
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; regioselective reaction;72%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

1,2,5-trifluoro-3-nitrobenzene
66684-57-9

1,2,5-trifluoro-3-nitrobenzene

Conditions
ConditionsYield
With 2CF3SO3H-B(OSO2CF3)3; nitric acid at 20℃; for 3h;83%
4-methylphenyl methylsulfide
623-13-2

4-methylphenyl methylsulfide

1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

2,3,6-trifluoro-4′-methyl-1,1′-biphenyl
1422961-31-6

2,3,6-trifluoro-4′-methyl-1,1′-biphenyl

Conditions
ConditionsYield
With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl) palladium(II) dichloride; 2,2,6,6-tetramethylpiperidinylzinc chloride lithium chloride complex In tetrahydrofuran at 80℃; for 7h; Inert atmosphere; regioselective reaction;83%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

2-(2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-(2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions
ConditionsYield
With bis(1,3-dimesityl-1H-imidazol-2(3H)-ylidene)nickel(0); C32H41O6P2Rh; cesium fluoride In 1,3,5-trimethyl-benzene at 25℃; for 6h; Irradiation; Inert atmosphere; Sealed tube; regioselective reaction;82%
1,2,4-trifluorobenzene
367-23-7

1,2,4-trifluorobenzene

C54H47B2ClN4

C54H47B2ClN4

C60H50B2ClF3N4

C60H50B2ClF3N4

Conditions
ConditionsYield
at 80℃; for 4h; Inert atmosphere; regioselective reaction;82%

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