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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

7-Amino-3-cephem-4-carboxylic acid Manufacturer/High quality/Best price/In stock

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 7-Anca supplier in China

Cas:36923-17-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

TNJ is a chemical company since 2001. Our specialization, your Confidence ! We keep committing to meet the needs of both market and customers with our innovative technology, high stable quality products and excellent service. We always combine econ

7-ANCA

Cas:36923-17-8

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

7-ANCA English name: 7-ANCA Chemical name: 7-Amino-3-norcephem-4-carboxylic acid; (7R)-7-amino-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Category involved: Intermed

7-ANCA

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 7-Anca

Cas:36923-17-8

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% 7-Amino-3-cephem-4-carboxylic acid 36923-17-8 GMP Manufacturer

Cas:36923-17-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

7-Amino-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality 7-ANCA/7-Amino-3-cephem-4-carboxylic acid CAS 36923-17-8

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

7-Amino-3-nor-3-cephem-4-carboxylic acid)

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--36923-17-8--High purity 7-Amino-3-cephem-4-carboxylic acid factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had estab

TIANFUCHEM--36923-17-8--High purity 7-Amino-3-cephem-4-carboxylic acid factory price

Cas:36923-17-8

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 36923-17-8 with best quality

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 7-Amino-3-nor-3-cephem-4-carboxylic acid Synonyms: 7-ANCA CAS: 36923-17-8 MF: C7H8N2O3S Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Organic synthesis Transport

7-Amino-3-nor-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

Ceftibutene Intermediate 36923-17-8 Ceftizoxime Intermediate

Cas:36923-17-8

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-amino-8-oxo-, (6R,7R)- 36923-17-8

Cas:36923-17-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

7-Amino-3-cephem-4-carboxylic acid CAS:36923-17-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

7-Amino-3-cephem-4-carboxylic acid CAS:36923-17-8

Cas:36923-17-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-amino-8-oxo-, (6R,7R)-

Cas:36923-17-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-amino-8-oxo-, (6R,7R)-

Cas:36923-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

7-Amino-3-Nor-3-Cephem-4-Carboxylic Acid

Cas:36923-17-8

Min.Order:0

Negotiable

Type:Manufacturers

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

7-NACA、7-ANCA

Cas:36923-17-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

7-NACA

Cas:36923-17-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

7-Amino-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci

7-Amino-3-cephem-4-carboxylic acid CAS 36923-17-8

Cas:36923-17-8

Min.Order:1 Kilogram

FOB Price: $150.0 / 180.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 7-Anca

Cas:36923-17-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

7-Amino-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Huarong Industrial Group Limited established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World.

7-ANCA

Cas:36923-17-8

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

7-Amino-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 7-ANCA CAS No.: 36923-17-8 Molecule Formula:C7H8N2O3S Molecule Weight:220.22 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITE

Lower Price 7-ANCA

Cas:36923-17-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

7-Amino-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

7-Amino-3-nor-3-cephem-4-carboxylic acid

Cas:36923-17-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Off-White Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Intermediates,ect. Transport

7-Amino-3-cephem-4-carboxylic acid supplier in China

Cas:36923-17-8

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Synthetic route

C7H9IN2O3S

C7H9IN2O3S

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 25 - 30℃; for 5h; pH=8 - 8.5;90.85%
C14H13N3O5S*ClH

C14H13N3O5S*ClH

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
With trimethylsilyl bromide In dichloromethane at 20 - 25℃; for 5.5h;89%
diphenylmethyl 7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
36923-21-4

diphenylmethyl 7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
With methoxybenzene; trifluoroacetic acid
(6R,7R)-benzhydryl 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
35246-64-1

(6R,7R)-benzhydryl 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: (PhCO)2O / dimethylsulfoxide / Ambient temperature
2: <(Ph3P)3Rh>Cl / benzene
3: (i) PCl5, Py, (ii) MeOH
4: PhOMe, CF3CO2H
View Scheme
diphenylmethyl (6R,7R)-7-(phenylacetamido)ceph-3-em-4-carboxylate
36923-19-0

diphenylmethyl (6R,7R)-7-(phenylacetamido)ceph-3-em-4-carboxylate

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: (i) PCl5, Py, (ii) MeOH
2: PhOMe, CF3CO2H
View Scheme
(6R)-3-formyl-8-oxo-7t-(2-phenyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
35246-65-2

(6R)-3-formyl-8-oxo-7t-(2-phenyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: <(Ph3P)3Rh>Cl / benzene
2: (i) PCl5, Py, (ii) MeOH
3: PhOMe, CF3CO2H
View Scheme
p-nitrobenzyl 7-phenylacetamido-3-hydroxy-3-cephalosporin-4-carboxylate
53116-50-0

p-nitrobenzyl 7-phenylacetamido-3-hydroxy-3-cephalosporin-4-carboxylate

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: diphenylsilyl chloride; aluminum (III) chloride / dichloromethane / 4 h / 15 - 25 °C
2.1: diisooctyl phenyl phosphite; bromine; 1H-imidazole / dichloromethane / 5 h / -45 - -40 °C
2.2: 0.5 h
3.1: trimethylsilyl bromide / dichloromethane / 5.5 h / 20 - 25 °C
View Scheme
(6R,7R)-1-aza-3-chloro-7-amino-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene-2-carboxylic acid
53994-69-7

(6R,7R)-1-aza-3-chloro-7-amino-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tetrahydroborate; ammonium hydroxide / water; methanol / 0.5 h / 15 - 25 °C / pH 7 - 7.5
2: sodium iodide; glycine; sodium hydrogencarbonate / acetone / 4 h / 25 - 30 °C / Sonication
3: potassium hydroxide / water; methanol / 5 h / 25 - 30 °C / pH 8 - 8.5
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C13H10N4O2S3

C13H10N4O2S3

ceftizoxime
68401-81-0

ceftizoxime

Conditions
ConditionsYield
Stage #1: (6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid With dmap In dichloromethane at -8 - 0℃;
Stage #2: C13H10N4O2S3 With dmap In dichloromethane at -5 - 0℃; for 0.25h; Reagent/catalyst; Temperature;
97%
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

{(Z)-3-[4-Benzhydryloxy-5-(4-methoxy-benzyloxy)-1-oxy-pyridin-2-yl]-isoxazol-5-ylmethoxyimino}-[2-(trityl-amino)-thiazol-4-yl]-acetic acid
159048-31-4

{(Z)-3-[4-Benzhydryloxy-5-(4-methoxy-benzyloxy)-1-oxy-pyridin-2-yl]-isoxazol-5-ylmethoxyimino}-[2-(trityl-amino)-thiazol-4-yl]-acetic acid

(6R,7R)-7-{2-{(Z)-3-[4-Benzhydryloxy-5-(4-methoxy-benzyloxy)-1-oxy-pyridin-2-yl]-isoxazol-5-ylmethoxyimino}-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
1026067-63-9

(6R,7R)-7-{2-{(Z)-3-[4-Benzhydryloxy-5-(4-methoxy-benzyloxy)-1-oxy-pyridin-2-yl]-isoxazol-5-ylmethoxyimino}-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
With pyridine; trichlorophosphate Substitution;96%
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

1-benzyl-4-fluoropyridinium bromide
77527-66-3

1-benzyl-4-fluoropyridinium bromide

C19H17N3O3S
79601-77-7

C19H17N3O3S

Conditions
ConditionsYield
With sodium hydroxide In water at 22℃; pH 7;54%
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

2-<(2-14C)-2-formylamino-4-thiazolyl>-(Z)-2-methoxyimino acetic acid

2-<(2-14C)-2-formylamino-4-thiazolyl>-(Z)-2-methoxyimino acetic acid

C13(14)CH13N5O6S2

C13(14)CH13N5O6S2

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

diazodiphenylmethane
908093-98-1

diazodiphenylmethane

diphenylmethyl 7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
36923-21-4

diphenylmethyl 7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Conditions
ConditionsYield
In acetonitrile
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C21H15N7O9S2(2-)*2Na(1+)

C21H15N7O9S2(2-)*2Na(1+)

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 96 percent / POCl3; pyridine
2.1: trifluoracetic acid / methoxybenzene / purified by chromatography and lyophilization
2.2: 81 percent / NaHCO3
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2-methoxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2-methoxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetonitrile
2: 63 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
3: 99 percent / Et3SiH, trifluoroacetic acid / 1,2-dichloro-ethane / 0 °C
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2-hydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2-hydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetonitrile
2: 69 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
3: 100 percent / Et3SiH, trifluoroacetic acid / 1,2-dichloro-ethane / 0 °C
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(3-hydroxy-pyridyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(3-hydroxy-pyridyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetonitrile
2: 62 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
3: 86 percent / Et3SiH, trifluoroacetic acid / 1,2-dichloro-ethane / 0 °C
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2,6-dihydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2,6-dihydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetonitrile
2: 55 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
3: 86 percent / Et3SiH, trifluoroacetic acid / 1,2-dichloro-ethane / 0 °C
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(3-hydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester
171017-68-8

(6R,7R)-7-<2-(3-hydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile
2: 63 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2-hydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester
171017-57-5

(6R,7R)-7-<2-(2-hydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile
2: 69 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(3-hydroxy-2-pyridyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester
171017-65-5

(6R,7R)-7-<2-(3-hydroxy-2-pyridyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile
2: 62 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
View Scheme
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-<2-(2,6-dihydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester
171017-61-1

(6R,7R)-7-<2-(2,6-dihydroxyphenyl)-4-thiazolyl>acetylamino-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid diphenylmethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile
2: 55 percent / morpho CDI / tetrahydrofuran; CH2Cl2 / 1.) 0 deg C, 24 h, 2.) 25 deg C, 5 h
View Scheme
2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetic acid
91868-79-0

2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetic acid

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

cefotaxime sodium salt
64485-93-4

cefotaxime sodium salt

Conditions
ConditionsYield
Stage #1: 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetic acid With dmap; dicyclohexyl-carbodiimide In ethanol at 20℃; for 0.5h;
Stage #2: With 1-hydroxy-pyrrolidine-2,5-dione In ethanol at 20℃; for 0.5h;
Stage #3: (6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Further stages;
2.59 g
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
36923-17-8

(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate
80756-85-0

(Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate

ceftizoxime
68401-81-0

ceftizoxime

Conditions
ConditionsYield
Stage #1: (6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid With triethylamine In chloroform for 0.333333h;
Stage #2: (Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate In chloroform at 35℃; for 4.5h; Temperature;
87 g
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