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Cas:64485-93-4
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inquiryProName: Cefotaxime Sodium CasNo: 64485-93-4 Molecular Formula: C16H16N5NaO7S2 Appearance: Look at the detailed information Application: intermediates DeliveryTime: according to the clients requir
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inquiryName: Cefotaxime Sodium Name: Cefotaxime sodium English synonyms: Cefotaxime: Claforan; Cefotaxime Sodium (250 mg) CAS No. 64485-93-4 Molecular formula: C16H16N5NaO7S2 Molecular weight: 477.45 EINECS No. 2
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inquiryCAS NO.: 64485-93-4 EINECS NO.: 264-915-9 MF: C16H16N5NaO7S2 MW: 477.45 Appearance:White crystalline powder Specification:99%min Standard: EP/BP/USP Odor: odorless Appearance:White powder Storage:Store in cool and dry place, away
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1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Cefotaxime sodium Structure: Formula: C16H16N5NaO7S2 Molecular Weight : 477.45 Synonyms: Cefotaxime:Claforan;FIR-756;(6R,7R)-7-[[(Z)-(2-Amino-4-thiazolyl)(
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inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
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cefotaxime
cefotaxime sodium salt
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In ethanol Substitution; | 95.4% |
With sodium isooctanoate; sodium sulfite In water; acetone at 5 - 10℃; for 0.5h; | 95% |
With triethylamine; sodium 2-ethylhexanoic acid In methanol; ethyl acetate | 88.7% |
cefotaxime
cefotaxime sodium salt
Conditions | Yield |
---|---|
With sodium acetate trihydrate In water; acetone |
7-Aminocephalosporanic acid
cefotaxime sodium salt
Conditions | Yield |
---|---|
Stage #1: 7-Aminocephalosporanic acid In water; acetone at 10℃; for 10h; Large scale; Stage #2: With sodium hydroxide In water; acetone at 10 - 15℃; pH=9.5; Temperature; pH-value; Large scale; |
2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetic acid
(6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
cefotaxime sodium salt
Conditions | Yield |
---|---|
Stage #1: 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetic acid With dmap; dicyclohexyl-carbodiimide In ethanol at 20℃; for 0.5h; Stage #2: With 1-hydroxy-pyrrolidine-2,5-dione In ethanol at 20℃; for 0.5h; Stage #3: (6R,7R)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Further stages; | 2.59 g |
2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetic acid
cefotaxime sodium salt
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 2.5 h / 2 - 25 °C 2: N,O-bis-(trimethylsilyl)-acetamide / acetonitrile / 1 h / -5 - 0 °C 3: sodium sulfite; sodium isooctanoate / water; acetone / 0.5 h / 5 - 10 °C View Scheme |
Conditions | Yield |
---|---|
In methanol for 1h; Reflux; | 77% |
water
cefotaxime sodium salt
Conditions | Yield |
---|---|
at 20℃; for 6h; | 72% |
Conditions | Yield |
---|---|
With methanesulfonic acid In acetonitrile at 20℃; for 3h; | 25% |
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water pH=4.5; | 24% |
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water pH=4.5; | 24% |
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water pH=4.5; | 16% |
O-benzyl-N-methylhydroxylamine hydrochloride
cefotaxime sodium salt
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water pH=4.5; | 14% |
cefotaxime sodium salt
A
2-<<(2-amino-4-thiazolyl)((Z)-methoxyimino)acetyl>amino>acetoaldehyde
Conditions | Yield |
---|---|
With sodium hydroxide at 95℃; for 0.416667h; |
cefotaxime sodium salt
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: aq. NaOH / 0.42 h / 95 °C 2.1: Na2B4O7*10H2O / H2O 2.2: H2O; acetone / 0.5 h / 25 °C View Scheme |
1-Cyclopropyl-4-thiopyridone
cefotaxime sodium salt
Conditions | Yield |
---|---|
With sodium iodide In water; acetone; acetonitrile |
Conditions | Yield |
---|---|
In methanol at 20℃; for 2h; |
3,6-dichloro-2,5-dihydroxy-1,4-benzoquinone
cefotaxime sodium salt
Conditions | Yield |
---|---|
In methanol at 20℃; for 2h; |
2,3-dicyano-5,6-dichloro-p-benzoquinone
cefotaxime sodium salt
Conditions | Yield |
---|---|
In methanol at 20℃; for 2h; |
7,7',8,8'-tetracyanoquinodimethane
cefotaxime sodium salt
Conditions | Yield |
---|---|
In methanol at 20℃; for 2h; |
Conditions | Yield |
---|---|
In aq. acetate buffer at 60℃; for 0.666667h; pH=5.5; pH-value; Concentration; Temperature; Solvent; |
Conditions | Yield |
---|---|
In aq. buffer at 40℃; for 0.666667h; pH=11; pH-value; Concentration; Temperature; Solvent; |
cefotaxime sodium salt
Conditions | Yield |
---|---|
With water In methanol | 80.87 g |
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