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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL

Cas:3947-65-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

Neamine

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL CAS:3947-65-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and devel

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Neamine

Cas:3947-65-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Neamine

Cas:3947-65-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Neamine

Cas:3947-65-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Neamine

Cas:3947-65-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Neamine

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Neamine

Cas:3947-65-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk productiongoods in stockswe have the best competitive price in the marketmeantime,we are committed to service to our every customer Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Neamine Application:Neamine

Neamine

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by courier/air/sea Port:Any port of China

Neamine 3947-65-7 CAS NO.: 3947-65-7

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOLAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediat

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Hunan Longxianng Runhui Trading Co.,Ltd

NeamineAppearance:white powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport) or by sea LCL/FCL for large amount.

Neamine

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

3947-65-7

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Neamine 3947-65-7

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

AstaTech ( Chengdu) BioPharmaceutical Corp.

Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu

neamine

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Neamine 3947-65-7

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

5-amino-2-(aminomethyl)-6-(4,6-diamino-2,3-dihydroxycyclohexyl)oxyoxane-3,4-diol

Cas:3947-65-7

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

Henan Fine Chemicals Co., Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHenan Fine Chemicals Co., LTD. is a diversified technology - oriented integrated company, which mainly concentrates on fine chemicals. Our company is committed to becom

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of plant in

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-

Cas:3947-65-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(1S,2R,3R,4S,6R)-4,6-Diamino-3-((2R,3R,4R,5R,6R)-3-amino-6-aminomethyl-4,5-bis-benzyloxy-tetrahydro-pyran-2-yloxy)-cyclohexane-1,2-diol
549501-35-1

(1S,2R,3R,4S,6R)-4,6-Diamino-3-((2R,3R,4R,5R,6R)-3-amino-6-aminomethyl-4,5-bis-benzyloxy-tetrahydro-pyran-2-yloxy)-cyclohexane-1,2-diol

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
With hydrogen; 20% palladium hydroxide on carbon In water; acetic acid91%
With hydrogen; acetic acid; palladium dihydroxide
neomycin B
119-04-0

neomycin B

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
With hydrogenchloride In methanol for 6h; Heating;82%
With hydrogenchloride In methanol for 4h; Reflux;80%
Stage #1: neomycin B With hydrogenchloride; methanol for 16h; acidic methanolysis;
Stage #2: With Amberlite IRA-400 (OH-) In methanol for 0.5h; Hydrolysis;
67%
With water Acidic conditions; Inert atmosphere;
neomycin B trisulfate

neomycin B trisulfate

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Stage #1: neomycin B trisulfate With hydrogenchloride In methanol for 6h; Heating;
Stage #2: With ammonium hydroxide; ammonia In methanol Further stages.;
70%
Conditions
ConditionsYield
With hydrogenchloride In methanol at 80℃; for 3h; pH=< 1;67%
neomycin B sulphate
25389-98-4

neomycin B sulphate

A

furfural
98-01-1

furfural

B

β-D-ribofuranose
36468-53-8

β-D-ribofuranose

C

neomycin A
3947-65-7

neomycin A

D

2,6-dideoxy-2,6-diamino-D-glucose
59433-00-0

2,6-dideoxy-2,6-diamino-D-glucose

E

(2R,3S,4R,5R,6R)-5-Amino-2-aminomethyl-6-((2R,3S,4R,5R)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-furan-3-yloxy)-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6R)-5-Amino-2-aminomethyl-6-((2R,3S,4R,5R)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-furan-3-yloxy)-tetrahydro-pyran-3,4-diol

Conditions
ConditionsYield
Product distribution; Rate constant; Irradiation; multistep reaction, radiolytic degradation;
neomycin B sulphate
25389-98-4

neomycin B sulphate

A

furfural
98-01-1

furfural

B

β-D-ribofuranose
36468-53-8

β-D-ribofuranose

C

neomycin A
3947-65-7

neomycin A

D

(2S,3R,4R,5S,6S)-3-Amino-6-aminomethyl-tetrahydro-pyran-2,4,5-triol

(2S,3R,4R,5S,6S)-3-Amino-6-aminomethyl-tetrahydro-pyran-2,4,5-triol

E

(2S,3S,4R,5R,6R)-5-Amino-2-aminomethyl-6-((2R,3S,4R,5R)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-furan-3-yloxy)-tetrahydro-pyran-3,4-diol

(2S,3S,4R,5R,6R)-5-Amino-2-aminomethyl-6-((2R,3S,4R,5R)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-furan-3-yloxy)-tetrahydro-pyran-3,4-diol

Conditions
ConditionsYield
Product distribution; Rate constant; Irradiation; multistep reaction, radiolytic degradation;
neomycin-B

neomycin-B

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
With hydrogenchloride; methanol
With hydrogenchloride
1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose
171032-74-9

1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 90 percent / ZnI2 / 1,2-dichloro-ethane / 50 °C
2: 98 percent / NaOMe / methanol
3: 94 percent / pyridine
4: 100 percent / NaN3 / dimethylformamide / 80 °C
5: 86 percent / NaH / dimethylformamide
6: N-iodosuccinimide; silver trifluoromethanesulfonate / diethyl ether; CH2Cl2 / -20 °C
7: NaOMe / methanol
8: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
9: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
phenyl 2-azido-2-deoxy-1-thio-α/β-D-glucopyranoside
202462-37-1

phenyl 2-azido-2-deoxy-1-thio-α/β-D-glucopyranoside

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 94 percent / pyridine
2: 100 percent / NaN3 / dimethylformamide / 80 °C
3: 86 percent / NaH / dimethylformamide
4: N-iodosuccinimide; silver trifluoromethanesulfonate / diethyl ether; CH2Cl2 / -20 °C
5: NaOMe / methanol
6: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
7: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
phenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-1-thio-α/β-D-glucopyranoside
183875-22-1

phenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-1-thio-α/β-D-glucopyranoside

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 98 percent / NaOMe / methanol
2: 94 percent / pyridine
3: 100 percent / NaN3 / dimethylformamide / 80 °C
4: 86 percent / NaH / dimethylformamide
5: N-iodosuccinimide; silver trifluoromethanesulfonate / diethyl ether; CH2Cl2 / -20 °C
6: NaOMe / methanol
7: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
8: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
phenyl 2,6-diazido-2,6-dideoxy-1-thio-α/β-D-glucopyranoside
632330-84-8

phenyl 2,6-diazido-2,6-dideoxy-1-thio-α/β-D-glucopyranoside

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 86 percent / NaH / dimethylformamide
2: N-iodosuccinimide; silver trifluoromethanesulfonate / diethyl ether; CH2Cl2 / -20 °C
3: NaOMe / methanol
4: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
5: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
Toluene-4-sulfonic acid (2R,3S,4R,5R)-5-azido-3,4-dihydroxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl ester
632330-83-7

Toluene-4-sulfonic acid (2R,3S,4R,5R)-5-azido-3,4-dihydroxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl ester

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 100 percent / NaN3 / dimethylformamide / 80 °C
2: 86 percent / NaH / dimethylformamide
3: N-iodosuccinimide; silver trifluoromethanesulfonate / diethyl ether; CH2Cl2 / -20 °C
4: NaOMe / methanol
5: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
6: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
(3R,4R,5R,6R)-3-Azido-6-azidomethyl-4,5-bis-benzyloxy-2-phenylsulfanyl-tetrahydro-pyran
549501-23-7

(3R,4R,5R,6R)-3-Azido-6-azidomethyl-4,5-bis-benzyloxy-2-phenylsulfanyl-tetrahydro-pyran

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: N-iodosuccinimide; silver trifluoromethanesulfonate / diethyl ether; CH2Cl2 / -20 °C
2: NaOMe / methanol
3: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
4: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
3′,4′-di-O-benzyl-1,3,2′,6′-tetraazidoneamine
549501-27-1

3′,4′-di-O-benzyl-1,3,2′,6′-tetraazidoneamine

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
2: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
Multi-step reaction with 2 steps
1: trimethylphosphane / tetrahydrofuran
2: hydrogen / 20% palladium hydroxide on carbon / water; acetic acid
View Scheme
5,6-di-O-acetyl-3',4'-di-O-benzyl-1,3,2',3'-tetraazidoneamine
549501-26-0

5,6-di-O-acetyl-3',4'-di-O-benzyl-1,3,2',3'-tetraazidoneamine

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaOMe / methanol
2: P(CH3)3; 0.1 N aq. NaOH / tetrahydrofuran
3: H2; aq. AcOH / 20 percent Pd(OH)2/C
View Scheme
neomycin B sulphate
25389-98-4

neomycin B sulphate

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
With hydrogenchloride
butan-1-ol
71-36-3

butan-1-ol

neomycin A
3947-65-7

neomycin A

Conditions
ConditionsYield
With acetic acid
neomycin A
3947-65-7

neomycin A

benzyl chloroformate
501-53-1

benzyl chloroformate

N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine
22854-75-7

N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine

Conditions
ConditionsYield
With sodium carbonate In acetone95%
With sodium hydrogencarbonate In acetone; toluene at 4℃;86%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

neomycin A
3947-65-7

neomycin A

{(1R,2S,3R,4R,5S)-5-tert-Butoxycarbonylamino-4-[(2R,3R,4R,5S,6R)-3-tert-butoxycarbonylamino-6-(tert-butoxycarbonylamino-methyl)-4,5-dihydroxy-tetrahydro-pyran-2-yloxy]-2,3-dihydroxy-cyclohexyl}-carbamic acid tert-butyl ester
54230-72-7

{(1R,2S,3R,4R,5S)-5-tert-Butoxycarbonylamino-4-[(2R,3R,4R,5S,6R)-3-tert-butoxycarbonylamino-6-(tert-butoxycarbonylamino-methyl)-4,5-dihydroxy-tetrahydro-pyran-2-yloxy]-2,3-dihydroxy-cyclohexyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
95%
C22H31N3O8

C22H31N3O8

neomycin A
3947-65-7

neomycin A

C25H48N6O11

C25H48N6O11

Conditions
ConditionsYield
In water; acetone for 1h;92%
C21H30N2O7

C21H30N2O7

neomycin A
3947-65-7

neomycin A

C24H47N5O10
936707-05-0

C24H47N5O10

Conditions
ConditionsYield
In water; acetone for 1h;92%
C27H24N2O6

C27H24N2O6

neomycin A
3947-65-7

neomycin A

C30H41N5O9
936707-01-6

C30H41N5O9

Conditions
ConditionsYield
In water; acetone for 1h;91%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

neomycin A
3947-65-7

neomycin A

1,3,2',6'-tetra-N-(tert-butoxycarbonyl)neamine

1,3,2',6'-tetra-N-(tert-butoxycarbonyl)neamine

Conditions
ConditionsYield
With triethylamine In methanol; water at 20℃; for 2h;91%
neomycin A
3947-65-7

neomycin A

2-Chloro-benzoic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester
100898-23-5

2-Chloro-benzoic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-2-chloro-benzamide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-2-chloro-benzamide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;90%
In water; acetonitrile at 20℃; for 0.5h;90 %Chromat.
neomycin A
3947-65-7

neomycin A

1,3,2′,6′-tetraazidoneamine
671809-10-2

1,3,2′,6′-tetraazidoneamine

Conditions
ConditionsYield
With triflic azide; copper(II) sulfate; triethylamine In methanol; dichloromethane; water Inert atmosphere;90%
With triflic azide; copper(II) ion77%
With triflic azide; copper(II) sulfate; triethylamine
γ-L-Glu-((S)-4-amino-2-hydroxybutyryl)-N-acetylcysteamine thioester
1064665-41-3

γ-L-Glu-((S)-4-amino-2-hydroxybutyryl)-N-acetylcysteamine thioester

neomycin A
3947-65-7

neomycin A

γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine
1141768-83-3

γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine

Conditions
ConditionsYield
With recombinant BtrH enzyme at 20℃; for 6h; pH=7.9; aq. buffer; Enzymatic reaction;90%
C26H22N2O6

C26H22N2O6

neomycin A
3947-65-7

neomycin A

C29H39N5O9
936707-00-5

C29H39N5O9

Conditions
ConditionsYield
In water; acetone for 1h;89%
neomycin A
3947-65-7

neomycin A

Boc-β-Ala-ONB
65785-41-3

Boc-β-Ala-ONB

C20H39N5O9
936707-03-8

C20H39N5O9

Conditions
ConditionsYield
In water; acetone for 1h;87%
Naphthalen-1-yl-acetic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

Naphthalen-1-yl-acetic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

neomycin A
3947-65-7

neomycin A

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-2-naphthalen-1-yl-acetamide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-2-naphthalen-1-yl-acetamide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;85%
In water; acetonitrile at 20℃; for 0.5h;85%
neomycin A
3947-65-7

neomycin A

N-benzoyloxy-5-norbornene-endo-2,3-dicarboximide
24147-30-6

N-benzoyloxy-5-norbornene-endo-2,3-dicarboximide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-benzamide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-benzamide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;80%
In water; acetone for 1h;80%
In water; acetonitrile at 20℃; for 0.5h;80%
neomycin A
3947-65-7

neomycin A

trityl chloride
76-83-5

trityl chloride

(2R,3S,4R,5R,6R)-6-[(1R,2R,3S,4R,6S)-2,3-Dihydroxy-4,6-bis-(trityl-amino)-cyclohexyloxy]-5-(trityl-amino)-2-[(trityl-amino)-methyl]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6R)-6-[(1R,2R,3S,4R,6S)-2,3-Dihydroxy-4,6-bis-(trityl-amino)-cyclohexyloxy]-5-(trityl-amino)-2-[(trityl-amino)-methyl]-tetrahydro-pyran-3,4-diol

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide77%
C12H9NO4

C12H9NO4

neomycin A
3947-65-7

neomycin A

C15H26N4O7

C15H26N4O7

Conditions
ConditionsYield
In water; acetone for 1h;77%
neomycin A
3947-65-7

neomycin A

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

1,2',3,6'-tetrakis-N-(trifluoroacetyl)neamine
61066-03-3

1,2',3,6'-tetrakis-N-(trifluoroacetyl)neamine

Conditions
ConditionsYield
With triethylamine In acetonitrile for 1h; Ambient temperature;75.3%
neomycin A
3947-65-7

neomycin A

Phenyl-acetic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester
100898-22-4

Phenyl-acetic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-2-phenyl-acetamide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-2-phenyl-acetamide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;75%
In water; acetonitrile at 20℃; for 0.5h;75%
C11H10N4O4

C11H10N4O4

neomycin A
3947-65-7

neomycin A

C14H27N7O7

C14H27N7O7

Conditions
ConditionsYield
In water; acetone for 1h;75%
neomycin A
3947-65-7

neomycin A

N-benzyloxycarbonyloxy-5-norbornene-endo-2,3-dicarboximide
1092494-97-7

N-benzyloxycarbonyloxy-5-norbornene-endo-2,3-dicarboximide

6'-N-benzyloxycarbonylneamine
77967-96-5

6'-N-benzyloxycarbonylneamine

Conditions
ConditionsYield
In 1,4-dioxane; water at 20℃; for 6h;72%
endo-N-hydroxy-5-norbornene-2,3-dicarboximide O-bromoacetate
872054-82-5

endo-N-hydroxy-5-norbornene-2,3-dicarboximide O-bromoacetate

neomycin A
3947-65-7

neomycin A

N-6'-bromoacetylneamine
220874-82-8

N-6'-bromoacetylneamine

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;70%
In water; acetone for 1h;70%
In water; acetone for 0.25h; Sonication;
In water; acetonitrile for 0.166667h; Product distribution / selectivity;
In water; acetone for 0.166667h;
Butyric acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

Butyric acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

neomycin A
3947-65-7

neomycin A

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-butyramide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-butyramide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;70%
In water; acetonitrile at 20℃; for 0.5h;70 %Chromat.
Dodecanoic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

Dodecanoic acid (1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester

neomycin A
3947-65-7

neomycin A

Dodecanoic acid [(2R,3S,4R,5R,6R)-5-amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-amide

Dodecanoic acid [(2R,3S,4R,5R,6R)-5-amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-amide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;70%
In water; acetonitrile at 20℃; for 0.5h;70 %Chromat.
neomycin A
3947-65-7

neomycin A

acetone O-<(vinyloxy)carbonyl>oxime
139705-38-7

acetone O-<(vinyloxy)carbonyl>oxime

{(1R,2S,3R,4R,5S)-4-[(2R,3R,4R,5S,6R)-4,5-Dihydroxy-3-vinyloxycarbonylamino-6-(vinyloxycarbonylamino-methyl)-tetrahydro-pyran-2-yloxy]-2,3-dihydroxy-5-vinyloxycarbonylamino-cyclohexyl}-carbamic acid vinyl ester
791064-36-3

{(1R,2S,3R,4R,5S)-4-[(2R,3R,4R,5S,6R)-4,5-Dihydroxy-3-vinyloxycarbonylamino-6-(vinyloxycarbonylamino-methyl)-tetrahydro-pyran-2-yloxy]-2,3-dihydroxy-5-vinyloxycarbonylamino-cyclohexyl}-carbamic acid vinyl ester

Conditions
ConditionsYield
With sodium hydroxide In phosphate buffer at 0℃; for 5h; pH=8.0;66%
neomycin A
3947-65-7

neomycin A

N-(t-butoxycarbonyloxy)-5-norbornene-endo-2,3-dicarboximide

N-(t-butoxycarbonyloxy)-5-norbornene-endo-2,3-dicarboximide

6'-N-(tert-Butoxycarbonyl)neamine
153953-67-4

6'-N-(tert-Butoxycarbonyl)neamine

Conditions
ConditionsYield
In 1,4-dioxane; water for 5h; Ambient temperature;65%
With triethylamine In 1,4-dioxane; water at 20℃; for 15.1667h;
2-acetoxy-(3ac,7ac)-3a,4,7,7a-tetrahydro-4r,7c-methano-isoindole-1,3-dione
24147-28-2

2-acetoxy-(3ac,7ac)-3a,4,7,7a-tetrahydro-4r,7c-methano-isoindole-1,3-dione

neomycin A
3947-65-7

neomycin A

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-acetamide

N-[(2R,3S,4R,5R,6R)-5-Amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-acetamide

Conditions
ConditionsYield
In water; acetonitrile for 0.5h; sonication;60%
In water; acetone for 1h;60%
In water; acetonitrile at 20℃; for 0.5h;60%
Nα-[(thymin-1-yl)acetyl]-Nε-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-L-arginine

Nα-[(thymin-1-yl)acetyl]-Nε-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-L-arginine

neomycin A
3947-65-7

neomycin A

6'-N-[Nα-[(thymin-1-yl)acetyl]-Nε-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-DL-arginyl]neamine
886208-72-6

6'-N-[Nα-[(thymin-1-yl)acetyl]-Nε-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-DL-arginyl]neamine

Conditions
ConditionsYield
Stage #1: Nα-[(thymin-1-yl)acetyl]-Nε-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-L-arginine With WSC*HCl In N,N-dimethyl-formamide for 3h;
Stage #2: neomycin A In water; N,N-dimethyl-formamide for 20h;
58.3%

Raw Materials

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