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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

tert-Butyl 3-oxoazetidine-1-carboxylate

Cas:398489-26-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Win-Win chemical Co.Ltd

Stock products, own laboratory Product number English Name 1-Boc-3-Azetidinone CAS Number 398489-26-4 Purity 98% Molecular formula C8H13

1-Boc-3-Azetidinone cas no. 398489-26-4 98%

Cas:398489-26-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1-Boc-3-azetidinone Manufacturer/High quality/Best price/In stock

Cas:398489-26-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1-Boc-Azetidin-3-One supplier in China

Cas:398489-26-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min -------------------------------------------------------------------------------

High purity 1-Boc-3-azetidinone CAS:398489-26-4

Cas:398489-26-4

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality tert-Butyl 3-oxoazetidine-1-carboxylate CAS 398489-26-4 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its interm

High quality tert-Butyl 3-oxoazetidine-1-carboxylate CAS 398489-26-4 with factory price

Cas:398489-26-4

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

1-(tert-Butoxycarbonyl)-3-azetidinone

Cas:398489-26-4

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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EAST CHEMSOURCES LIMITED

1-Boc-3-azetidinone [Chemical Name]: 1-Boc-3-azetidinone [Synonyms ]: tert-Butyl 3-oxoazetidine-1-carboxylate; 3-OXO-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER; 3-OXOAZETIDINE, N-BOC PRO

1-Boc-3-azetidinone

Cas:398489-26-4

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Tert-butyl 3-oxoazetidine-1-carboxylate

Cas:398489-26-4

Min.Order:1

Negotiable

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

1-Boc-3-azetidinone

Cas:398489-26-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

CHemwill -- 1-Boc-3-azetidinone

Cas:398489-26-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1460.html Product Name 1-Boc-3-azetidinone CAS No. 398489-26-4

1-Boc-3-azetidinone

Cas:398489-26-4

Min.Order:1 Gram

FOB Price: $11.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tert-Butyl 3-oxoazetidine-1-carboxylate 398489-26-4

Cas:398489-26-4

Min.Order:1 Metric Ton

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 398489-26-4 with best quality

Cas:398489-26-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

1-Boc-3-azetidinone/ LIDE PHARMA- Factory supply / Best price

Cas:398489-26-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

[Chemical Name]: 1-Boc-3-azetidinone [Synonyms ]: tert-Butyl 3-oxoazetidine-1-carboxylate; 3-OXO-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER; 3-OXOAZETIDINE, N-BOC PROTECTED; 1-Boc-azetidin

1-Boc-3-azetidinone

Cas:398489-26-4

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

1-BOC-3-azetidinone manufacturer/supplier

Cas:398489-26-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Factory supply 1-Boc-3-azetidinone cas 398489-26-4

Cas:398489-26-4

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Boc-3-azetidinone 398489-26-4

Cas:398489-26-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: tert-Butyl 3-oxoazetidine-1-carboxylate CAS: 398489-26-4 MF: C8H13NO3 MW: 171.19 EINECS: 627-725-0 Mol File: 398489-26-4.mol tert-Butyl 3-oxoazetidine-1-carboxylate Structure tert-Butyl 3-oxoazetidine-1-carboxylate C

N-BOC-3-Azetidinone

Cas:398489-26-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

tert-Butyl 3-oxoazetidine-1-carboxylate

Cas:398489-26-4

Min.Order:1 Kilogram

FOB Price: $76.0 / 85.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

tert-Butyl 3-oxoazetidine-1-carboxylate CAS:398489-26-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high

tert-Butyl 3-oxoazetidine-1-carboxylate CAS:398489-26-4

Cas:398489-26-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Boc-3-azetidinone

Cas:398489-26-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:398489-26-4

Cas:398489-26-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

tert-Butyl 3-oxoazetidine-1-carboxylate CAS: 398489-26-4 Specification Item Specification Appearance White Crystalline Powder Assay 98%min Density 1.174±0.06 g/cm3(Predicted) Meltin

Factory supply tert-Butyl 3-oxoazetidine-1-carboxylate

Cas:398489-26-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

tert-Butyl 3-oxoazetidine-1-carboxylate

Cas:398489-26-4

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

tert-butyl 3-oxoazetidine-1-carboxylate CAS NO.398489-26-4

Cas:398489-26-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1-Boc-Azetidin-3-One

Cas:398489-26-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

tert-Butyl3-oxoazetidine-1-carboxylate

Cas:398489-26-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Triumph International Development Limilted

Appearance:Off-white to white solid powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:By Sea/Air/Courier Port:

Baricitinib intermediates|398489-26-4

Cas:398489-26-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

tert-butyl 3-hydroxyazetidine-1-carboxylate
141699-55-0

tert-butyl 3-hydroxyazetidine-1-carboxylate

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide In acetonitrile at 0 - 20℃; for 18h; Inert atmosphere; Molecular sieve;99%
With 1-methyl-1H-imidazole; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; 4,4'-Dimethoxy-2,2'-bipyridin; 9-azabicyclo[3.3.1]nonane N-oxyl; oxygen In acetonitrile at 20℃; for 0.5h; Time;98%
With pyridine-SO3 complex; triethylamine In dimethyl sulfoxide at 10 - 20℃; Inert atmosphere;95%
1,3-dibromoacetone ethylene glycol
20599-01-3

1,3-dibromoacetone ethylene glycol

tert-butyl carbamate
4248-19-5

tert-butyl carbamate

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane at 50℃; for 16h; Reagent/catalyst; Solvent; Temperature;92%
1-tert-butoxycarbonyl-3,3-dimethoxyazetidine

1-tert-butoxycarbonyl-3,3-dimethoxyazetidine

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
With citric acid In water; ethyl acetate at 20 - 40℃;85.4%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3,3-dimethoxyazetidine

3,3-dimethoxyazetidine

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 10 - 40℃;80.2%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide / tetrahydrofuran / 1 h / 20 °C
2: triethylamine / sulfur trioxide pyridine complex / chloroform; dimethyl sulfoxide / 4 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / 1,4-dioxane; water / 15 h / 20 °C
2: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / 15 h / -78 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / ethanol / 16 h / 0 - 20 °C
2: pyridine-SO3 complex; triethylamine / dimethyl sulfoxide / 10 - 20 °C / Inert atmosphere
View Scheme
tert-butyl 3-hydroxyazetidine-1-carboxylate
141699-55-0

tert-butyl 3-hydroxyazetidine-1-carboxylate

A

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

B

1,1-dimethylethyl 5-oxo-3-oxazolidinecarboxylate
172096-95-6

1,1-dimethylethyl 5-oxo-3-oxazolidinecarboxylate

Conditions
ConditionsYield
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium hydrogencarbonate; potassium bromide In dichloromethane; water at -10 - -5℃; Temperature;
methylene-carbamic acid tert-butyl ester
801290-71-1

methylene-carbamic acid tert-butyl ester

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: trichlorophosphate / diethyl ether / Inert atmosphere; Schlenk technique; Reflux
2: zinc; acetic acid / 7 h / 20 - 80 °C / Inert atmosphere; Schlenk technique
View Scheme
C8H11Cl2NO3

C8H11Cl2NO3

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Conditions
ConditionsYield
With acetic acid; zinc at 20 - 80℃; for 7h; Inert atmosphere; Schlenk technique;
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

dimethyl amine
124-40-3

dimethyl amine

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate
792970-55-9

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: tert-butyl 3-oxoazetidine-1-carboxylate; dimethyl amine With hydrogen; acetic acid; palladium 10% on activated carbon In tetrahydrofuran; methanol at 20℃; for 14h;
Stage #2: With sodium hydrogencarbonate In water; ethyl acetate
100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

3-methylene-azetidine-1-carboxylic acid tert-butyl ester
934664-41-2

3-methylene-azetidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: potassium tert-butylate; Methyltriphenylphosphonium bromide In diethyl ether at 20℃; for 1h;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In diethyl ether at 35℃; for 2h;
100%
Stage #1: Methyltriphenylphosphonium bromide With potassium tert-butylate In diethyl ether at 20℃; for 1h;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In diethyl ether at 35℃; for 2h;
100%
Stage #1: Methyltriphenylphosphonium bromide With potassium tert-butylate In diethyl ether at 20℃; for 1h;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In diethyl ether at 35℃; for 2h;
100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

(triphenylphosphoranylidene)acetaldehyde
2136-75-6

(triphenylphosphoranylidene)acetaldehyde

tert-butyl 3-(2-oxomethylene)azetidine-1-carboxylic acid
1223573-23-6

tert-butyl 3-(2-oxomethylene)azetidine-1-carboxylic acid

Conditions
ConditionsYield
In dichloromethane at 40℃; for 6h;100%
In dichloromethane at 40℃; for 6h;100%
In dichloromethane at 40℃;99%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

vinyl magnesium bromide
1826-67-1

vinyl magnesium bromide

tert-butyl 3-hydroxy-3-vinylazetidine-1-carboxylate
398489-51-5

tert-butyl 3-hydroxy-3-vinylazetidine-1-carboxylate

Conditions
ConditionsYield
In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;100%
In tetrahydrofuran at -20℃; for 0.5h; Inert atmosphere;99%
In tetrahydrofuran at -30℃; for 2h; Inert atmosphere;
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

tert-butyl 3-(2-ethoxy-2-oxoethylidene)azetidine-1-carboxylate
1002355-96-5

tert-butyl 3-(2-ethoxy-2-oxoethylidene)azetidine-1-carboxylate

Conditions
ConditionsYield
In dichloromethane for 6h; Wittig Olefination; Inert atmosphere; Schlenk technique; Reflux;100%
In dichloromethane at 40℃; for 4h; Cooling with ice;100%
In dichloromethane at 40℃; for 4.25h; Cooling with ice;100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

tert-butyl diethylphosphonoacetate
27784-76-5

tert-butyl diethylphosphonoacetate

tert-butyl 3-(2-(tert-butoxy)-2-oxoethylidene)azetidine-1-carboxylate

tert-butyl 3-(2-(tert-butoxy)-2-oxoethylidene)azetidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: tert-butyl diethylphosphonoacetate With potassium tert-butylate In tetrahydrofuran at 0 - 20℃;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In tetrahydrofuran at 0 - 20℃;
100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

(carbobenzyloxymethylene)triphenylphosphorane
15097-38-8

(carbobenzyloxymethylene)triphenylphosphorane

tert-butyl 3-(2-benzyloxy-2-oxo-ethylidene)azetidine-1-carboxylic acid

tert-butyl 3-(2-benzyloxy-2-oxo-ethylidene)azetidine-1-carboxylic acid

Conditions
ConditionsYield
In toluene for 2h; Reflux;100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

(S)-1-amino-2-(methoxymethyl)pyrrolidine
59983-39-0

(S)-1-amino-2-(methoxymethyl)pyrrolidine

C14H25N3O3

C14H25N3O3

Conditions
ConditionsYield
at 55℃; for 16h;100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

5-bromo-2,3-dihydro-1H-isoindole hydrochloride
919346-89-7

5-bromo-2,3-dihydro-1H-isoindole hydrochloride

tert-butyl-3-(5-bromoisoindolin-2-yl)azetidine-1-carboxylate

tert-butyl-3-(5-bromoisoindolin-2-yl)azetidine-1-carboxylate

Conditions
ConditionsYield
With acetic acid In methanol at 50℃; for 16h;100%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

diethyl 1-cyanomethylphosphonate
2537-48-6

diethyl 1-cyanomethylphosphonate

3-(cyanomethylene)azetidine-1-carboxylic acid tert-butyl ester
1153949-11-1

3-(cyanomethylene)azetidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: diethyl 1-cyanomethylphosphonate With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In tetrahydrofuran; mineral oil Product distribution / selectivity;
99%
Stage #1: diethyl 1-cyanomethylphosphonate With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In tetrahydrofuran at 0℃;
Stage #3: With water In tetrahydrofuran
98%
Stage #1: diethyl 1-cyanomethylphosphonate With potassium tert-butylate In tetrahydrofuran at 0 - 30℃;
Stage #2: tert-butyl 3-oxoazetidine-1-carboxylate In tetrahydrofuran at 0 - 30℃;
95%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

methylmagnesium chloride
676-58-4

methylmagnesium chloride

tert-butyl 3-hydroxy-3-methylazetidine-1-carboxylate
1104083-23-9

tert-butyl 3-hydroxy-3-methylazetidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: tert-butyl 3-oxoazetidine-1-carboxylate; methylmagnesium chloride In tetrahydrofuran at 0℃; for 1h;
Stage #2: With water; ammonium chloride In tetrahydrofuran
99%
Stage #1: tert-butyl 3-oxoazetidine-1-carboxylate; methylmagnesium chloride In tetrahydrofuran at 0 - 20℃; for 6h;
Stage #2: With water; ammonium chloride In tetrahydrofuran at 0℃; for 0.166667h;
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

tert-butyl 3-hydroxyazetidine-1-carboxylate
141699-55-0

tert-butyl 3-hydroxyazetidine-1-carboxylate

Conditions
ConditionsYield
With sodium tetrahydroborate; ethanol for 2h;99%
With sodium tetrahydroborate In tetrahydrofuran at 20℃; for 6h;84%
With methanol; sodium tetrahydroborate at 0 - 20℃; for 1h;
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

3-methylene-azetidine-1-carboxylic acid tert-butyl ester
934664-41-2

3-methylene-azetidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With potassium tert-butylate; methyl-triphenylphosphonium iodide In diethyl ether at 35℃; for 2h;99%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

1-triphenylphosphoranylidene-2-propanone
1439-36-7

1-triphenylphosphoranylidene-2-propanone

tert-butyl 3-acetonylideneazetidine-1-carboxylate

tert-butyl 3-acetonylideneazetidine-1-carboxylate

Conditions
ConditionsYield
In toluene at 70℃; for 2h;99%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

nitromethane
75-52-5

nitromethane

3-hydroxy-3-(nitromethyl)azetidin-1-carboxylic acid tert-butyl ester
1008526-70-2

3-hydroxy-3-(nitromethyl)azetidin-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With triethylamine In ethanol at 20℃; for 16h; Inert atmosphere;98%
With triethylamine In ethanol at 20℃; for 16h;98%
triethylamine In ethanol for 18h;97%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

4-methoxybenzenesulfonyl hydrazide
1950-68-1

4-methoxybenzenesulfonyl hydrazide

tert-butyl 3-(2-((4-methoxyphenyl)sulfonyl)hydrazineylidene)azetidine-1-carboxylate
1510865-67-4

tert-butyl 3-(2-((4-methoxyphenyl)sulfonyl)hydrazineylidene)azetidine-1-carboxylate

Conditions
ConditionsYield
In toluene for 2h; Reflux;98%
In dimethylsulfoxide-d6 at 60℃; Schlenk technique;73%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

methyl iodide
74-88-4

methyl iodide

tert-butyl 3-methoxyazetidine-1-carboxylate
429669-07-8

tert-butyl 3-methoxyazetidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: tert-butyl 3-oxoazetidine-1-carboxylate With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
98%
azetidine
503-29-7

azetidine

tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

tert-butyl [1,3'-biazetidine]-1'-carboxylate

tert-butyl [1,3'-biazetidine]-1'-carboxylate

Conditions
ConditionsYield
Stage #1: azetidine; tert-butyl 3-oxoazetidine-1-carboxylate With acetic acid In 1,2-dichloro-ethane at 20℃;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane for 4h;
98%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

tert-butyl 3-ethyl-3-hydroxyazetidine-1-carboxylate
398489-28-6

tert-butyl 3-ethyl-3-hydroxyazetidine-1-carboxylate

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; for 5h; Inert atmosphere;98%
tert-butyl 3-oxoazetidine-1-carboxylate
398489-26-4

tert-butyl 3-oxoazetidine-1-carboxylate

4-Octyne
1942-45-6

4-Octyne

tert-butyl 3-oxo-4,5-dipropyl-3,6-dihydropyridine-1(2H)-carboxylate
1372173-47-1

tert-butyl 3-oxo-4,5-dipropyl-3,6-dihydropyridine-1(2H)-carboxylate

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); triphenylphosphine In toluene at 60℃; for 6h; Inert atmosphere; regioselective reaction;97%
With bis(1,5-cyclooctadiene)nickel (0); triphenylphosphine In toluene at 60℃; for 6h; Glovebox; Inert atmosphere;97%
With bis(triphenylphosphine)nickel(II) chloride; zinc In acetonitrile at 60℃; for 16h; Catalytic behavior; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere;95%

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