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Hefei Zhaobo Technology Co., Ltd.

L-5-Hydroxytryptophan CAS 4350-09-8 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality con

L-5-Hydroxytryptophan CAS 4350-09-8

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Hebei Miheng Trading Co., Ltd.

L-5-Hydroxytryptophan CAS 4350-09-8 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assemb

L-5-Hydroxytryptophan CAS 4350-09-8

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

L-5-Hydroxytryptophan Manufacturer/High quality/Best price/In stock

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Griffonia Seed P .E supplier in China

Cas:4350-09-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

L-5-Hydroxytryptophan CAS NO.4350-09-8

Cas:4350-09-8

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White or off-white powder Storage:2-8°C Packa

Ghana seed extract L-5-Hydroxytryptophan 5-HTP CAS 4350-09-8 with high purity

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $400.0 / 500.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion of extract according to the demand . Excellent Team We are a young and profess

Factory supply griffonia seed extract 5-htp powder with bulk price

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $60.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Griffonia Seed P .E

Cas:4350-09-8

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% L-Tryptophan,5-hydroxy- 4350-09-8 ISO Producer

Cas:4350-09-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

TIANFU-CHEM CAS NO.4350-09-8 Polyurethane foams

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Product Description Product Name 5-HTP Appearance Off-white powder Assay Min 98% test by HPLC Molecular formula C11H12N203 Molecular weight 220.23 Appearance:White Solid Powder Storag

Bulk 5-Hydroxytryptophan 5 Htp Powder Food Supplement 5-Htp.

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $50.0 / 80.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 4350-09-8 with best quality

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

China supplier 5-HTP CAS NO.4350-09-8

Cas:4350-09-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

L-5-Hydroxytryptophan/ LIDE PHARMA- Factory supply / Best price

Cas:4350-09-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Brown yellow or white fine powder Storage:Store in sealed c

Pure Natural Plant Extract 5-Hydroxytryptophan CAS No.:4350-09-8 5-HTP

Cas:4350-09-8

Min.Order:100 Gram

Negotiable

Type:Other

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

5-HTP Delivery Fast Hot Sale Natural Vegetation Seeds Extract 5-hydroxytryptophan powder

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $130.0 / 180.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

L-Tryptophan,5-hydroxy- 4350-09-8

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Shanghai Minstar Chemical Co., Ltd

Synonyms: 5-hydroxy-l-tryptopha;pretonine;C5-HYDROXY-L-TRYPTOPHAN;H-5-HYDROXY-TRP-OH;H-TRP(5-OH)-OH;L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;L-5-HYDROXYTRYPTOPHAN HYDRATE;L-5-HYDROXYTRYPTOPHAN CAS: 4350-09-8 MF: C11H12N2O3 MW: 220.22 EINECS

L-5-HYDROXYTRYPTOPHAN 4350-09-8 large in supply

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:white powder/ Refer to COA Storage:Refer to COA

5-HTP 4350-09-8 cas 99% ready stock L-5-Hydroxytryptophan

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

High quality L-5-Hydroxytryptophan 4350-09-8 in stock fast delivery good supplier

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 99.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

L-5-Hydroxytryptophan CAS:4350-09-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte

L-5-Hydroxytryptophan CAS:4350-09-8

Cas:4350-09-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

L-Tryptophan,5-hydroxy-

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory sales L-5-Hydroxytryptophan CAS 4350-09-8

Cas:4350-09-8

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

L-Tryptophan,5-hydroxy-

Cas:4350-09-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:white to pale grey powder Storage:Room temperature Package:25kg/drum Application:Ghana Seed Extract Transportation:Express/Sea/Air Port:Any port in china

Factory Supply 5-HTP L-5-Hydroxytryptophan With Bulk Price

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

L-5-Hydroxytryptophan

Cas:4350-09-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

L-5-Hydroxytryptophan

Cas:4350-09-8

Min.Order:1 Kilogram

FOB Price: $180.0 / 200.0

Type:Lab/Research institutions

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-HTP cas no.4350-09-8 0.98

Cas:4350-09-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

L-Tryptophan,5-hydroxy-

Cas:4350-09-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

indol-5-ol
1953-54-4

indol-5-ol

L-serin
56-45-1

L-serin

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
Stage #1: indol-5-ol; L-serin With pyridoxal 5'-phosphate; thermotoga maritima with tryptophan synthase β-subunit from pyrococcus furiosus M145T N167D mutant In aq. phosphate buffer; water; dimethyl sulfoxide at 75℃; for 2h; pH=8; Sealed tube; Enzymatic reaction;
Stage #2: With hydrogenchloride In water
93%
With transformed Escherichia coli cells at 37℃; for 24h;70 % Chromat.
With tryptophan synthase; pyridoxal 5'-phosphate at 37℃; for 24h; pH=7.8; Enzymatic reaction;
DL-5-hydroxytryptophane amide
90830-06-1

DL-5-hydroxytryptophane amide

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
43%
43%
L-Tryptophan
73-22-3

L-Tryptophan

A

7-Hydroxy-L-tryptophan
25198-02-1

7-Hydroxy-L-tryptophan

B

4-Hydroxy-L-tryptophan
25242-90-4

4-Hydroxy-L-tryptophan

C

(S)-6-hydroxytryptophan
13567-14-1

(S)-6-hydroxytryptophan

D

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
With dihydrogen peroxide; edetate disodium; iron(II) sulfate; ascorbic acid In water at 22℃; for 0.0416667h;A n/a
B 10%
C n/a
D 12%
L-N-benzyloxycarbonyl-5-benzyloxytryptophan
3520-59-0

L-N-benzyloxycarbonyl-5-benzyloxytryptophan

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
With ethanol; palladium Hydrogenation;
5-benzyloxy-Nα-benzyloxycarbonyl-DL-tryptophan
3017-27-4

5-benzyloxy-Nα-benzyloxycarbonyl-DL-tryptophan

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: quinine
2: palladium; ethanol / Hydrogenation
View Scheme
L-Tryptophan
73-22-3

L-Tryptophan

A

tryptamine
61-54-1

tryptamine

B

L-kynurenine
2922-83-0

L-kynurenine

C

hydroxyhexahydropyrrolo[2,3-b]indole-2-carboxylic acid

hydroxyhexahydropyrrolo[2,3-b]indole-2-carboxylic acid

D

(S )-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid

(S )-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid

E

hydroxyoxoindolylalanine

hydroxyoxoindolylalanine

F

2-amino-3-(2-oxoindolin-3-yl)propanoic acid
236094-74-9

2-amino-3-(2-oxoindolin-3-yl)propanoic acid

G

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
With dihydrogen peroxide at 37℃; for 6h; pH=4.6; Darkness; aq. borate buffer;
L-Tryptophan
73-22-3

L-Tryptophan

L-5-HTP
4350-09-8

L-5-HTP

Conditions
ConditionsYield
With tryptophan hydroxylase Enzymatic reaction;
With ferrous ammonium sulphate; 6-methyl-5,6,7,8-tetrahydrobopterin; tryptophan hydroxylase; oxygen In aq. buffer at 20℃; for 0.333333h; pH=7.7; Kinetics; Mechanism; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Enzymatic reaction; chemoselective reaction;
methanol
67-56-1

methanol

L-5-HTP
4350-09-8

L-5-HTP

5-hydroxy-DL-tryptophan methyl ester hydrochloride

5-hydroxy-DL-tryptophan methyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride at -5 - 20℃; for 16h;98%
With thionyl chloride at 0 - 20℃; Inert atmosphere;74%
L-5-HTP
4350-09-8

L-5-HTP

3-(2-aminoethyl)-1H-indol-5-ol
50-67-9

3-(2-aminoethyl)-1H-indol-5-ol

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; aromatic L-amino acid decarboxylase In various solvent(s) at 30℃; for 48h;97%
With NH4OH-NH4Cl buffer; pyridoxal 5'-phosphate at 30℃; for 0.5h; relative rate of CO2 evolution by aromatic L-amino acid decarboxylase from Micrococcus percitreus;
With isopropyl β-D-thiogalactoside; L-tryptophan decarboxylase in recombinant Escherichia coli at 28℃;
9-methoxy-9-BBN
38050-71-4

9-methoxy-9-BBN

L-5-HTP
4350-09-8

L-5-HTP

C19H25BN2O3

C19H25BN2O3

Conditions
ConditionsYield
With pyridine97%
methanol
67-56-1

methanol

L-5-HTP
4350-09-8

L-5-HTP

2-amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid methyl ester
79812-02-5

2-amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid methyl ester

Conditions
ConditionsYield
With thionyl chloride at 0 - 40℃; for 10h;95%
With thionyl chloride at -5 - 35℃; for 5h;92.9%
With hydrogenchloride at 0 - 20℃; for 18h; Fischer esterification;
copper(ll) bromide
7789-45-9

copper(ll) bromide

L-5-HTP
4350-09-8

L-5-HTP

[copper(II)(L-5-hydroxytryptophan)2(bromide)2] monohydrate

[copper(II)(L-5-hydroxytryptophan)2(bromide)2] monohydrate

Conditions
ConditionsYield
In methanol for 3h; Reflux;89%
3,4-dichlorophenylisocyanate
102-36-3

3,4-dichlorophenylisocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(3,4-dichlorophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(3,4-dichlorophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 2.5h;89%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-5-HTP
4350-09-8

L-5-HTP

(S)-2-tert-butoxycarbonylamino-3-(5-tert-butoxycarbonyloxy-1H-indol-3-yl)propionic acid
390816-59-8

(S)-2-tert-butoxycarbonylamino-3-(5-tert-butoxycarbonyloxy-1H-indol-3-yl)propionic acid

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol for 5h; pH=11.5 - 12.0;87%
nickel(II) bromide trihydrate

nickel(II) bromide trihydrate

L-5-HTP
4350-09-8

L-5-HTP

[nickel(II)(L-5-hydroxytryptophan)2(methanol)2(bromide)2]

[nickel(II)(L-5-hydroxytryptophan)2(methanol)2(bromide)2]

Conditions
ConditionsYield
In methanol for 3h; Reflux;86%
2,6-difluorophenylisothiocyanate
207974-17-2

2,6-difluorophenylisothiocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(2,6-difluorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(2,6-difluorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 3h;85%
2,4-diflurophenylisocyanate
59025-55-7

2,4-diflurophenylisocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(2,4-difluorophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(2,4-difluorophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 4h;85%
copper(II) choride dihydrate

copper(II) choride dihydrate

L-5-HTP
4350-09-8

L-5-HTP

[copper(II)(L-5-hydroxytryptophan)2(chloride)2]

[copper(II)(L-5-hydroxytryptophan)2(chloride)2]

Conditions
ConditionsYield
In methanol for 3h; Reflux;84.8%
nickel(II) nitrate hexahydrate

nickel(II) nitrate hexahydrate

L-5-HTP
4350-09-8

L-5-HTP

[nickel(II)(L-5-hydroxytryptophan)2(nitrate)2] methanol disolvate monohydrate

[nickel(II)(L-5-hydroxytryptophan)2(nitrate)2] methanol disolvate monohydrate

Conditions
ConditionsYield
In methanol for 3h; Reflux;84%
3,4-dichlorophenyl isothiocyanate
6590-94-9

3,4-dichlorophenyl isothiocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(3,4-dichlorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(3,4-dichlorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 4h;83%
cobalt(II) chloride hexahydrate

cobalt(II) chloride hexahydrate

L-5-HTP
4350-09-8

L-5-HTP

[cobalt(II)(L-5-hydroxytryptophan)2(chloride)2] pentahydrate

[cobalt(II)(L-5-hydroxytryptophan)2(chloride)2] pentahydrate

Conditions
ConditionsYield
In methanol for 3h; Reflux;82.8%
cobalt(II) bromide

cobalt(II) bromide

L-5-HTP
4350-09-8

L-5-HTP

[cobalt(II)(L-5-hydroxytryptophan)2(bromide)2]

[cobalt(II)(L-5-hydroxytryptophan)2(bromide)2]

Conditions
ConditionsYield
In methanol for 3h; Reflux;82.6%
nickel(II) chloride hexahydrate

nickel(II) chloride hexahydrate

L-5-HTP
4350-09-8

L-5-HTP

[nickel(II)(L-5-hydroxytryptophan)2(methanol)2(chloride)2] monohydrate

[nickel(II)(L-5-hydroxytryptophan)2(methanol)2(chloride)2] monohydrate

Conditions
ConditionsYield
In methanol for 3h; Reflux;82.6%
copper(II) nitrate trihydrate

copper(II) nitrate trihydrate

L-5-HTP
4350-09-8

L-5-HTP

[copper(II)(L-5-hydroxytryptophan)2(nitrate)2] monohydrate

[copper(II)(L-5-hydroxytryptophan)2(nitrate)2] monohydrate

Conditions
ConditionsYield
In methanol for 3h; Reflux;82.6%
methanol
67-56-1

methanol

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-5-HTP
4350-09-8

L-5-HTP

(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(5-hydroxy-1H-indol-3-yl)propanoate
203736-17-8

(S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(5-hydroxy-1H-indol-3-yl)propanoate

Conditions
ConditionsYield
Stage #1: methanol; L-5-HTP With thionyl chloride at 0 - 20℃; for 12h;
Stage #2: di-tert-butyl dicarbonate With triethylamine In dichloromethane at 0 - 20℃; for 6h;
82%
4-bromophenyl isocyanate
2493-02-9

4-bromophenyl isocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(4-bromophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(4-bromophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 3h;82%
3-indolylglyoxal
7269-72-9

3-indolylglyoxal

L-5-HTP
4350-09-8

L-5-HTP

6-hydroxy-1-(1H-indole-3-carbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
1350653-01-8

6-hydroxy-1-(1H-indole-3-carbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: 3-indolylglyoxal; L-5-HTP With sulfuric acid In water at 20℃; for 10h; Pictet-Spengler cyclisation;
Stage #2: With ammonia In water at 0℃; for 12h; pH=6 - 7;
80%
1-isothiocyanato-3-trifluoromethyl-benzene
1840-19-3

1-isothiocyanato-3-trifluoromethyl-benzene

L-5-HTP
4350-09-8

L-5-HTP

3-(5-hydroxy-1H-indol-3-yl)-2-(3-(3-trifluoromethylphenyl)thioureido)propanoic acid

3-(5-hydroxy-1H-indol-3-yl)-2-(3-(3-trifluoromethylphenyl)thioureido)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 3h;80%
4-fluorophenyl isothiocyanate
1544-68-9

4-fluorophenyl isothiocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(4-fluorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(4-fluorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran79%
3-chloro-4-fluorophenyl isothiocyanate
137724-66-4

3-chloro-4-fluorophenyl isothiocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(3-chloro-4-fluorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(3-chloro-4-fluorophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 4h;79%
3-bromophenyl isothiocyanate
2131-59-1

3-bromophenyl isothiocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(3-bromophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(3-bromophenyl)thioureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 3.5h;78%
zinc dibromide

zinc dibromide

L-5-HTP
4350-09-8

L-5-HTP

[zinc(II)(L-5-hydroxytryptophan)2(bromide)2] monohydrate

[zinc(II)(L-5-hydroxytryptophan)2(bromide)2] monohydrate

Conditions
ConditionsYield
In methanol for 3h; Reflux;77.2%
1,3-dimethylbarbituric acid
769-42-6

1,3-dimethylbarbituric acid

L-5-HTP
4350-09-8

L-5-HTP

5-hydroxy-L-tryptophan 1,3-dimethylbarbituric acid complex

5-hydroxy-L-tryptophan 1,3-dimethylbarbituric acid complex

Conditions
ConditionsYield
In water at 100℃; for 0.5h;77%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-5-HTP
4350-09-8

L-5-HTP

(S)-2-((tert-butoxycarbonyl)amino)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
119768-45-5

(S)-2-((tert-butoxycarbonyl)amino)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran; water at 20℃; for 2h;76%
Stage #1: di-tert-butyl dicarbonate; L-5-HTP With sodium hydrogencarbonate In water at 0 - 35℃; for 24h;
Stage #2: With citric acid In water pH=6;
58.16%
With triethylamine In 1,4-dioxane at 20℃;
[Ru(η(6)-cymene)(acetone)3](CF3SO3)2

[Ru(η(6)-cymene)(acetone)3](CF3SO3)2

trifluoroacetic acid
76-05-1

trifluoroacetic acid

L-5-HTP
4350-09-8

L-5-HTP

[(η6-p-cymene)Ru(η6-5-hydroxytryptophan)](CF3SO3)2*CF3COOH

[(η6-p-cymene)Ru(η6-5-hydroxytryptophan)](CF3SO3)2*CF3COOH

Conditions
ConditionsYield
In trifluoroacetic acid ligand was added to Ru-complex in CF3COOH, stirred for 12 h at 50°C; pptd. with Et2O, dried in vac.; elem. anal.;75%
p-chlorphenylisocyanate
104-12-1

p-chlorphenylisocyanate

L-5-HTP
4350-09-8

L-5-HTP

2-(3-(4-chlorophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

2-(3-(4-chlorophenyl)ureido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Conditions
ConditionsYield
With pyridine; triethylamine In tetrahydrofuran for 3.5h;75%

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