Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:462-20-4
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:462-20-4
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:462-20-4
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:462-20-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:462-20-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:462-20-4
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:462-20-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryProduct Name: DIHYDROLIPOIC ACID Synonyms: DHLA;(+/-)-DIHYDROLIPOIC ACID;DIHYDROLIPOIC ACID;DL-ALPHA-LIPOIC ACID REDUCED FORM;DL-ALPHA-LIPOIC ACID, DIHYDRO-;DL-6,8-THIOCTIC ACID, REDUCED;DL-6,8-THIOCTIC ACID REDUCED FORM;DL-1,2-
Cas:462-20-4
Min.Order:1 Metric Ton
FOB Price: $20.0
Type:Lab/Research institutions
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:462-20-4
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:462-20-4
Min.Order:1 Metric Ton
FOB Price: $7.0 / 8.0
Type:Trading Company
inquiryhigh purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:462-20-4
Min.Order:1 bottle
Negotiable
Type:Lab/Research institutions
inquiryIndependent research and development of impurities, familiar with the market and impurity characteristics; We can ship out on the same day if the products are in stock; Focus on impurity development of new products in the market; Expert in customizi
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:462-20-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirySupply top quality products with a reasonable price Application:api
Octanoic acid,6,8-dimercapto- cas 462-20-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:200mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po
The factory supplies Application:manufacturing supplies
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP
1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:462-20-4
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryChangzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa
Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right
Thioctic acid
dihydrolipoic acid
Conditions | Yield |
---|---|
With sodium tetrahydroborate; sodium hydrogencarbonate In water at 20℃; for 3h; | 100% |
Stage #1: Thioctic acid With sodium hydrogencarbonate In water Stage #2: With sodium tetrahydroborate In water at 0 - 20℃; for 1.33333h; Stage #3: With hydrogenchloride In water at 0℃; pH=1; | 100% |
With sodium tetrahydroborate; sodium hydrogencarbonate at 0℃; for 3h; | 99.5% |
Conditions | Yield |
---|---|
With hydrogenchloride; sodium borohydrid; sodium hydrogencarbonate In water | 100% |
With sodium tetrahydroborate; sodium hydrogencarbonate In water at 5 - 20℃; for 1.25h; | 96.8 mg |
(+/-)-8-hydroxy-6-mercapto-octanoic acid
thiourea
dihydrolipoic acid
Conditions | Yield |
---|---|
With hydrogen bromide anschliessend mit wss. Natronlauge; |
2-(2-Benzoyloxyethyl)cyclohexanone
dihydrolipoic acid
Conditions | Yield |
---|---|
(i) AcOOH, (ii) thiourea, aq. HI, (iii) aq. KOH; Multistep reaction; |
1,4-dithio-D,L-threitol
Thioctic acid
A
dihydrolipoic acid
trans-1,2-dithiane-4,5-diol
Conditions | Yield |
---|---|
In water-d2 for 48h; Equilibrium constant; phosphate buffer (pD 7.0); also in CD3OD/D2O; |
N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine
Thioctic acid
A
dihydrolipoic acid
B
1,2-dimethyl-3,8-dioxo-1,2,5,6-diazadithiocane
Conditions | Yield |
---|---|
With buffer (pH 7.0, 2 mM EDTA, 0.1 M phosphate) Equilibrium constant; |
2-hydroxyethanethiol
Thioctic acid
A
dihydrolipoic acid
B
bis(2-hydroxyethyl) disulfide
Conditions | Yield |
---|---|
In water-d2 for 48h; Equilibrium constant; phosphate buffer (pD 7.0); also in CD3OD/D2O; |
A
dihydrolipoic acid
B
Thioctic acid
Conditions | Yield |
---|---|
With potassium hydroxide; water for 3h; Hydrolysis; Rearrangement; Cyclization; Heating; Title compound not separated from byproducts; |
dihydrolipoic acid
Conditions | Yield |
---|---|
With phosphoric acid | |
With ammonia; sodium; toluene |
dihydrolipoic acid
Conditions | Yield |
---|---|
With sodium hydroxide beim Erhitzen des Reaktionsprodukts mit Thioharnstoff und wss. Jodwasserstoffsaeure und anschliessend Erhitzen mit wss. Natronlauge; | |
With sodium hydroxide beim Erhitzen des Reaktionsprodukts mit Thioharnstoff und wss. Jodwasserstoffsaeure und anschliessend Erhitzen mit wss. Natronlauge; |
thiourea
dihydrolipoic acid
Conditions | Yield |
---|---|
With hydrogen iodide beim Erhitzen des Reaktiosgemisches mit wss. Kalilauge unter Stickstoff; |
thiourea
dihydrolipoic acid
Conditions | Yield |
---|---|
With hydrogen iodide beim Erhitzen des Reaktiosgemisches mit wss. Kalilauge unter Stickstoff; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: HBr; H2O / 20 h / 116 °C 2: KOH; H2O / 3 h / Heating View Scheme | |
Multi-step reaction with 3 steps 1: HBr; H2O / 20 h / 116 °C 2: KOH; H2O / 3 h / Heating 3: NaBH4; NaHCO3 / H2O / 0.5 h / 5 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: HBr; H2O / 20 h / 116 °C 2.1: KOH; H2O / 3 h / Heating 2.2: FeCl3; air / H2O / 2.5 h / pH 8.8 - 11.5 3.1: NaBH4; NaHCO3 / H2O / 0.5 h / 5 °C View Scheme |
A
dihydrolipoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: KOH; H2O / 3 h / Heating 2: NaBH4; NaHCO3 / H2O / 0.5 h / 5 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: KOH; H2O / 3 h / Heating 1.2: FeCl3; air / H2O / 2.5 h / pH 8.8 - 11.5 2.1: NaBH4; NaHCO3 / H2O / 0.5 h / 5 °C View Scheme |
(+/-)-3-acetylsulfanyl-octanedioic acid-8-ethyl ester-1-chloride
dihydrolipoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium borate; dioxane / beim Erwaermen des Reaktionsprodukts mit wss.-methanol. Natronlauge und wenig Zink-Pulver 2: aqueous hydrobromic acid / anschliessend mit wss. Natronlauge View Scheme |
Thioctic acid
6-[N-(4-Aminobutyl)-N-ethylamino]-2,3-dihydrophthalazine-1,4-dione
A
dihydrolipoic acid
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol |
Conditions | Yield |
---|---|
Stage #1: 6,8-dichlorooctanoic acid ethyl ester With sodium sulfide; hydrogen sulfide In ethanol; water under 2625.26 Torr; for 3.41667h; Large scale; Stage #2: With sodium tetrahydroborate; water; sodium hydroxide In ethanol at 70℃; for 2.5h; Pressure; Temperature; Time; Reagent/catalyst; Large scale; |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 100% |
Stage #1: dihydrolipoic acid; ortho-anisaldehyde In dichloromethane at 20℃; for 1h; Inert atmosphere; Stage #2: With boron trifluoride diethyl etherate In dichloromethane at -25 - 20℃; Inert atmosphere; |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 99.4% |
Stage #1: dihydrolipoic acid; 3-Trifluoromethylbenzaldehyde In dichloromethane at 20℃; for 1h; Inert atmosphere; Stage #2: With boron trifluoride diethyl etherate In dichloromethane at -25 - 20℃; Inert atmosphere; |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 99.4% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 97.6% |
methanol
dihydrolipoic acid
methyl 5-(2-chloro-1,3,2-dithiabisman-4-yl)pentanoate
Conditions | Yield |
---|---|
at 20℃; for 2h; Inert atmosphere; Darkness; | 96% |
Conditions | Yield |
---|---|
With iodine pentoxide In dimethyl sulfoxide at 110℃; for 24h; chemoselective reaction; | 94% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 93.8% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 93.1% |
Stage #1: dihydrolipoic acid; 2-chloro-benzaldehyde In dichloromethane at 20℃; for 1h; Inert atmosphere; Stage #2: With boron trifluoride diethyl etherate In dichloromethane at -25 - 20℃; Inert atmosphere; |
dihydrolipoic acid
acetone
5-(2,2-dimethyl-1,3-dithian-4-yl)pentanoic acid
Conditions | Yield |
---|---|
With yttrium(III) trifluoromethanesulfonate In acetonitrile | 93% |
With boron trifluoride diethyl etherate at 60℃; | 75% |
With boron trifluoride diethyl etherate at 60℃; | 75% |
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In dichloromethane at 45℃; for 12h; Inert atmosphere; | 91% |
Stage #1: dihydrolipoic acid; 2-methylphenyl aldehyde In dichloromethane at 20℃; for 1h; Inert atmosphere; Stage #2: With boron trifluoride diethyl etherate In dichloromethane at -25 - 20℃; Inert atmosphere; |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 90.9% |
dihydrolipoic acid
1,1,1,3,3,3-hexamethyl-disilazane
trimethylsilyl 6-mercapto-8-(trimethylsilylthio)octanoate
Conditions | Yield |
---|---|
With 1H-imidazole at 100℃; for 24h; Inert atmosphere; | 90% |
dihydrolipoic acid
bismuth(III) oxide
8,6-bis[[4-(4-carboxybutyl)-1,3,2-dithiabisman-2-yl]thio]octanoic acid
Conditions | Yield |
---|---|
In methanol at 20℃; for 48h; Darkness; | 89% |
dihydrolipoic acid
antimony(III) chloride
5-(2-chloro-1,3,2-dithiastibinan-4-yl)pentanoic acid
Conditions | Yield |
---|---|
In acetonitrile at 20℃; for 5h; | 86% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 83.9% |
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In dichloromethane at 20℃; for 1h; Inert atmosphere; | 83.1% |
methanol
dihydrolipoic acid
A
1,2-dithiolane-3-pentanoic acid methyl ester
B
methyl 8,6-bis[[4-(5-methoxy-5-oxopentyl)-1,3,2-dithiabisman-2-yl]thio]octanoate
Conditions | Yield |
---|---|
at 20℃; for 5h; Inert atmosphere; Darkness; Overall yield = 175 mg; | A 7 %Spectr. B 81% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 80.1% |
dihydrolipoic acid
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In methanol; water at 40℃; for 1h; Cyclization; | 80% |
dihydrolipoic acid
6,8-bis-(3-phosphanyl-propylsulfanyl)-octanoic acid
Conditions | Yield |
---|---|
Stage #1: dihydrolipoic acid With sodium hydride In tetrahydrofuran at 0℃; for 0.333333h; Metallation; Stage #2: (3-bromopropyl)phosphine In tetrahydrofuran for 12h; Alkylation; Heating; | 80% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 79% |
Stage #1: dihydrolipoic acid; 4-methyl-benzaldehyde In dichloromethane at 20℃; for 1h; Inert atmosphere; Stage #2: With boron trifluoride diethyl etherate In dichloromethane at -25 - 20℃; Inert atmosphere; |
dihydrolipoic acid
benzaldehyde
5-(2-phenyl-1,3-dithian-4-yl)pentanoic acid
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 1h; Inert atmosphere; | 78% |
With polyphosphoric acid trimethylsilyl ester In dichloromethane at 20℃; for 2h; | 60% |
With hydrogenchloride; zinc(II) chloride |
Conditions | Yield |
---|---|
for 5h; Inert atmosphere; Darkness; | 77% |
Conditions | Yield |
---|---|
In tetrahydrofuran (N2), stirred at room temp. for 48 h; concd. (vac), ppt. washed (THF), dried briefly (vac.); elem. anal.; | 76% |
Conditions | Yield |
---|---|
With trifluoroacetic acid In dichloromethane at 20℃; for 3h; | 76% |
dihydrolipoic acid
bismuth(III) oxide
5,5'-[oxybis(1,3,2-dithiabismane-2,4-diyl)]dipentanoic acid
Conditions | Yield |
---|---|
In methanol at 20℃; for 48h; Darkness; | 76% |
methanol
dihydrolipoic acid
A
1,2-dithiolane-3-pentanoic acid methyl ester
B
methyl 8,6-bis[[4-(5-methoxy-5-oxopentyl)-1,3,2-dithiabisman-2-yl]thio]octanoate
Conditions | Yield |
---|---|
at 20℃; for 24h; Darkness; Overall yield = 149 mg; | A 8 %Spectr. B 72% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View