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HANGZHOU YUNUO CHEMICAL CO.,LTD

Hangzhou Yunuo Chemical Co., Ltd is located in Hangzhou city China. As a global supplier in the chemical industry, Yunuochem is to create added value for customers around the world. Sticking to such business idea of "Good faith wins the bu

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,2-Dimeththylol Propionic Acid supplier in China

Cas:4767-03-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience 2. Free samples will be provided,ensure specifications and quality are right for customer 3. Customers will receive the most professional techn

Large Stock 99.0% 2,2-Bis(hydroxymethyl)propionic acid 4767-03-7 Producer

Cas:4767-03-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,2-bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1

Negotiable

Type:Other

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Jinan Finer Chemical Co., Ltd

Product description: Product name 2,2-Bis(hydroxymethyl)propionic acid CAS number 4767-03-7 Assay ≥99% Appearance White crystal Capacity 200mt/year Application For water-solu

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

2,2-DIMETHYLOLPROPIONIC ACID 4767-03-7 /manufacturer/low price/high quality/in stock

Cas:4767-03-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 6.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

2,2-Bis(hydroxymethyl)propionic acid Manufacturer Factory CAS 4767-03-7 2,2-Bis(hydroxymethyl)propionic acid Manufacturer High quality Best price In stock factory CAS 4767-03-7 2,2-Bis(hydroxymethyl)propionic acid COA TDS price MSDS Name

2,2-Bis(hydroxymethyl)propionic acid Manufacturer Factory CAS 4767-03-7

Cas:4767-03-7

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:2,2-Bis(hydroxymethyl)propionic acid CAS NO: 4767-03-7 Grade:Medical scientific research and export Molecular formula:C5H10O4 Molecular weight:134.1231 Product Quality 12 years of chemical raw materials Mature operation of the industry

2,2-Bis(hydroxymethyl)propionic acid/cas:4767-03-7/Raw material spot

Cas:4767-03-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 2,2-Bis(hydroxymethyl)propionic acid Synonyms: 2,2-Dimethylol Propionic Acid(DMPA);2,2-bis(hydroxymethyl)propanoicacid;3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid;3-hydroxy-2-(hydroxymethyl)-2-methyl-propanoicaci;3-hydroxy-2-(

,2-Bis(hydroxymethyl)propionic acid 4767-03-7

Cas:4767-03-7

Min.Order:1 Kilogram

FOB Price: $300.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2, 2-Dimethylol Propionic Acid (DMPA) CAS 4767-03-7

Cas:4767-03-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 4767-03-7 with fast shipping

Cas:4767-03-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:10 Kilogram

FOB Price: $30.0 / 50.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

2,2-Dimethylolpropionic acid(DMPA) Product Name: (2,2-Dimethylol Propionic Acid) Structural Formula: CH3-C(CH2OH)2-COOH Molecular Formula: C5H10O4 Molecular Weight:

2-2-Dimethylolpropionic acid CAS:4767-03-7

Cas:4767-03-7

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Free flowing granular solid Storage:R.T Package:25kg/drum Application:Used as chemical intermediates Transportation:Sea/Air/Express Port:Any port in China

Factory Supply High Quality 2-2-Dimethylolpropionic Acid 4767-03-7

Cas:4767-03-7

Min.Order:25 Kilogram

FOB Price: $5.3 / 7.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Technical Details

China Largest factory Manufacturer Supply 2,2-Bis(hydroxymethyl)propionic acid CAS 4767-03-7

Cas:4767-03-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,2-Bis(hydroxymethyl)propionic acid 4767-03-7

Cas:4767-03-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2,2-Bis(hydroxymethyl)propionic acid CAS:4767-03-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali

2,2-Bis(hydroxymethyl)propionic acid CAS:4767-03-7

Cas:4767-03-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

Lonwin Industry group limited as a professional manufactor & exporter of chemical materials ,we totally haver more than 270 stuffs, we have been on this line for more than 9 years. Our chemical materials are exported to lot of countries and regio

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Hangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting 2,2-Bis(hydroxymethyl)propionic acid;DMPA cas 4767-03-7;Please contact us by email freely. We are leading exporter in China. If you

2,2-Bis(hydroxymethyl)propionic acid;DMPA cas 4767-03-7 from Fandachem

Cas:4767-03-7

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,2-Dimethylol Propionic Acid

Cas:4767-03-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

2,2-Bis(hydroxymethyl)propionic acid CAS 4767-03-7

Cas:4767-03-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Dimethylolpropionic Acid

Cas:4767-03-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2,2-Bis(hydroxymethyl)propionic acid

Cas:4767-03-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,2-Dimeththylol Propionic Acid

Cas:4767-03-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Synthetic route

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal
18516-18-2

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal

A

2-(hydroxymethyl)-2-methylpropane-1,3-diol
77-85-0

2-(hydroxymethyl)-2-methylpropane-1,3-diol

B

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

Conditions
ConditionsYield
With potassium hydroxide
3-acetoxy-2-acetoxymethyl-2-methyl-propionitrile
98960-49-7

3-acetoxy-2-acetoxymethyl-2-methyl-propionitrile

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

Conditions
ConditionsYield
With hydrogenchloride beim Erhitzen des Reaktionsgemisches mit Wasser;
With hydrogenchloride
3-hydroxy-2-hydroxymethyl-2-methylpropionic acid methyl ester
17872-55-8

3-hydroxy-2-hydroxymethyl-2-methylpropionic acid methyl ester

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

Conditions
ConditionsYield
With potassium hydroxide
β.β'-dibromo-pivalic acid

β.β'-dibromo-pivalic acid

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

Conditions
ConditionsYield
With water; lead(II) oxide
β.β'-dichloro-pivalic acid

β.β'-dichloro-pivalic acid

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

Conditions
ConditionsYield
With sodium hydroxide
3-hydroxy-2-(hydroxymethyl)-2-methylpropanal
18516-18-2

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal

alcoholic potash

alcoholic potash

A

2-(hydroxymethyl)-2-methylpropane-1,3-diol
77-85-0

2-(hydroxymethyl)-2-methylpropane-1,3-diol

B

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal
18516-18-2

3-hydroxy-2-(hydroxymethyl)-2-methylpropanal

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

Conditions
ConditionsYield
With dihydrogen peroxide
With sulfuric acid In water Kinetics; Mechanism; Electrolysis;
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2-Isocyanatoethyl methacrylate
30674-80-7

2-Isocyanatoethyl methacrylate

C19H28N2O10
304698-73-5

C19H28N2O10

Conditions
ConditionsYield
Stage #1: 2,2-bis(hydroxymethyl)propionic acid; 2-Isocyanatoethyl methacrylate With dibutyltin dilaurate In tetrahydrofuran at 20℃;
Stage #2: With methanol In tetrahydrofuran for 2h;
100%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

1,1-diethoxycyclohexane
1670-47-9

1,1-diethoxycyclohexane

3-methyl-1,5-dioxa-spiro-[5,5]undecane-3-carboxylic acid

3-methyl-1,5-dioxa-spiro-[5,5]undecane-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: 1,1-diethoxycyclohexane; toluene-4-sulfonic acid In toluene at 120 - 130℃;
Stage #2: 2,2-bis(hydroxymethyl)propionic acid In toluene at 120 - 130℃; for 2.5h;
100%
Stage #1: 1,1-diethoxycyclohexane; toluene-4-sulfonic acid In toluene at 120 - 130℃; Reflux;
Stage #2: 2,2-bis(hydroxymethyl)propionic acid In toluene for 2.5h; Reflux;
triethyl borate
150-46-9

triethyl borate

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

B(2,2-bis(hydroxymethyl)propionate(3-))
1188369-88-1

B(2,2-bis(hydroxymethyl)propionate(3-))

Conditions
ConditionsYield
In ethanol100%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2-bromoethanol
540-51-2

2-bromoethanol

C7H14O5

C7H14O5

Conditions
ConditionsYield
Stage #1: 2,2-bis(hydroxymethyl)propionic acid With potassium hydroxide In N,N-dimethyl-formamide at 100℃; for 2h;
Stage #2: 2-bromoethanol In N,N-dimethyl-formamide at 45 - 50℃; for 48h;
100%
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2,2-bis(methylol)-3-methyl-3-carboxy-tert-butylacetate
1351112-99-6

2,2-bis(methylol)-3-methyl-3-carboxy-tert-butylacetate

Conditions
ConditionsYield
Stage #1: 2,2-bis(hydroxymethyl)propionic acid With potassium hydroxide In N,N-dimethyl-formamide at 100℃; for 1h;
Stage #2: bromoacetic acid tert-butyl ester In N,N-dimethyl-formamide at 100℃; for 15h;
99%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

α,α-bischloromethyl propionyl chloride
4301-04-6

α,α-bischloromethyl propionyl chloride

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide for 32h; Reflux;99%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

acetyl chloride
75-36-5

acetyl chloride

2,2-bis(acetoxymethyl)propionic acid
17872-58-1

2,2-bis(acetoxymethyl)propionic acid

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 0.5h;98%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid
16837-14-2

2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetone at 20℃; Inert atmosphere;98%
Stage #1: 2,2-bis(hydroxymethyl)propionic acid; toluene-4-sulfonic acid In benzene Reflux;
Stage #2: 2,2-dimethoxy-propane In benzene for 3h;
96.9%
Stage #1: 2,2-bis(hydroxymethyl)propionic acid; toluene-4-sulfonic acid In benzene Reflux;
Stage #2: 2,2-dimethoxy-propane In benzene for 1h;
96.9%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

phenylboronic acid
98-80-6

phenylboronic acid

5-methyl-2-phenyl-1,3,2-dioxaborinane-5-carboxylic acid
839720-60-4

5-methyl-2-phenyl-1,3,2-dioxaborinane-5-carboxylic acid

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 3h;98%
In tetrahydrofuran for 3h;94%
n-Octylamine
111-86-4

n-Octylamine

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

3-Hydroxy-2-hydroxymethyl-2-methyl-N-octyl-propionamide
137607-92-2

3-Hydroxy-2-hydroxymethyl-2-methyl-N-octyl-propionamide

Conditions
ConditionsYield
With tertiary amine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate97%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

ortho-bromobenzaldehyde
6630-33-7

ortho-bromobenzaldehyde

2-(2-bromophenyl)-5-methyl-1,3-dioxane-5-carboxylic acid

2-(2-bromophenyl)-5-methyl-1,3-dioxane-5-carboxylic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 80℃;97%
methanol
67-56-1

methanol

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

3-hydroxy-2-hydroxymethyl-2-methylpropionic acid methyl ester
17872-55-8

3-hydroxy-2-hydroxymethyl-2-methylpropionic acid methyl ester

Conditions
ConditionsYield
With Amberlyst-15 for 5h; Reflux;97%
With amberlyst 15 hydrogen form for 22h; Reflux;97%
With thionyl chloride at 62℃; for 18h;75%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

C80H130O49

C80H130O49

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 180 - 185℃; for 10h; Inert atmosphere;97%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

C21H38O6

C21H38O6

Conditions
ConditionsYield
With pyridine In N,N-dimethyl-formamide at 40℃; for 6h; Inert atmosphere;96%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

octadecyldimethyl[3-(trimethoxysilyl)propyl]ammonium chloride
27668-52-6

octadecyldimethyl[3-(trimethoxysilyl)propyl]ammonium chloride

dimethyloctadecyl-[3-tris(2-carboxy-3-hydroxy-2-methylpropoxy)silylpropyl]ammonium chloride

dimethyloctadecyl-[3-tris(2-carboxy-3-hydroxy-2-methylpropoxy)silylpropyl]ammonium chloride

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 145℃;96%
copper (II) carbonate hydroxide

copper (II) carbonate hydroxide

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

copper(II) 2,2-bis(hydroxymethyl)propionate

copper(II) 2,2-bis(hydroxymethyl)propionate

Conditions
ConditionsYield
In water at 100℃; for 6h;96%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

4-bromodeacetyl colchicine

4-bromodeacetyl colchicine

4-bromo-N-[2,2-bis(hydroxymethyl)propionyl]deacetyl colchicine

4-bromo-N-[2,2-bis(hydroxymethyl)propionyl]deacetyl colchicine

Conditions
ConditionsYield
Stage #1: 2,2-bis(hydroxymethyl)propionic acid With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: 4-bromodeacetyl colchicine In N,N-dimethyl-formamide at 20℃;
95.6%
ethanol
64-17-5

ethanol

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

ethyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
51689-18-0

ethyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate

Conditions
ConditionsYield
With Dowex at 95℃; for 72h; Fischer–Speier Esterification; Molecular sieve; Inert atmosphere; Schlenk technique;95.4%
With AMBERLYST 15 Reflux;91%
With Amberlyst-15 Reflux;86%
With sulfuric acid for 3h; Heating;77%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

1,1-dimethoxy-1,2,3,4-tetrahydronaphthalene
105644-28-8

1,1-dimethoxy-1,2,3,4-tetrahydronaphthalene

5-methyl-3',4'-dihydro-2'H-spiro[1,3-dioxane-2,1'-naphthalene]-5-carboxylic acid
1296664-74-8

5-methyl-3',4'-dihydro-2'H-spiro[1,3-dioxane-2,1'-naphthalene]-5-carboxylic acid

Conditions
ConditionsYield
toluene-4-sulfonic acid In toluene at 25 - 30℃; Reflux;95.28%
Stage #1: 2,2-bis(hydroxymethyl)propionic acid; toluene-4-sulfonic acid In toluene at 25 - 30℃;
Stage #2: 1,1-dimethoxy-1,2,3,4-tetrahydronaphthalene In toluene for 4h; Reflux;
95.28%
n-Dodecylamine
124-22-1

n-Dodecylamine

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

N-Dodecyl-3-hydroxy-2-hydroxymethyl-2-methyl-propionamide
137607-94-4

N-Dodecyl-3-hydroxy-2-hydroxymethyl-2-methyl-propionamide

Conditions
ConditionsYield
With tertiary amine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate95%
1-aminodecane
2016-57-1

1-aminodecane

2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

N-Decyl-3-hydroxy-2-hydroxymethyl-2-methyl-propionamide
137607-93-3

N-Decyl-3-hydroxy-2-hydroxymethyl-2-methyl-propionamide

Conditions
ConditionsYield
With tertiary amine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate95%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2-(perfluoro-n-octyl)ethylamine
30670-30-5

2-(perfluoro-n-octyl)ethylamine

N-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-decyl)-3-hydroxy-2-hydroxymethyl-2-methyl-propionamide
137607-96-6

N-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-decyl)-3-hydroxy-2-hydroxymethyl-2-methyl-propionamide

Conditions
ConditionsYield
With tertiary amine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate95%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylamine
30556-86-6

3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctylamine

3-Hydroxy-2-hydroxymethyl-2-methyl-N-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-propionamide
137607-95-5

3-Hydroxy-2-hydroxymethyl-2-methyl-N-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-propionamide

Conditions
ConditionsYield
With tertiary amine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate94%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

potassium 2, 2-bis(hydroxymethyl)propanoate

potassium 2, 2-bis(hydroxymethyl)propanoate

Conditions
ConditionsYield
With potassium hydroxide In water at 20℃;94%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

allyl bromide
106-95-6

allyl bromide

3-(allyloxy)-2-((allyloxy)methyl)-2-methylpropanoic acid
174822-36-7

3-(allyloxy)-2-((allyloxy)methyl)-2-methylpropanoic acid

Conditions
ConditionsYield
With sodium hydroxide In toluene at 110℃;92%
With sodium hydroxide In toluene at 110℃;90.97%
With sodium hydroxide In toluene for 21h; Reflux;90%
With sodium hydroxide In toluene Reflux;80%
Stage #1: 2,2-bis(hydroxymethyl)propionic acid With sodium hydroxide In toluene at 110℃; for 0.5h;
Stage #2: allyl bromide In toluene Reflux;
77%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

acetone
67-64-1

acetone

2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid
16837-14-2

2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 20℃; for 3h;92%
With toluene-4-sulfonic acid at 20℃; for 12h;86%
With toluene-4-sulfonic acid
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

1-dodecylbromide
143-15-7

1-dodecylbromide

dodecyl-2,2-bis(methylol)propionate

dodecyl-2,2-bis(methylol)propionate

Conditions
ConditionsYield
Stage #1: 2,2-bis(hydroxymethyl)propionic acid With potassium hydroxide In N,N-dimethyl-formamide; acetonitrile at 100℃; for 1h;
Stage #2: 1-dodecylbromide In N,N-dimethyl-formamide; acetonitrile
91%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

benzaldehyde dimethyl acetal
1125-88-8

benzaldehyde dimethyl acetal

5-methyl-2-phenyl-1,3-dioxane-5-carboxylic acid
207850-04-2

5-methyl-2-phenyl-1,3-dioxane-5-carboxylic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetone for 2h; Ambient temperature;90%
With toluene-4-sulfonic acid In acetone74.02%
With toluene-4-sulfonic acid In acetone at 20℃; for 4h;64%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid

2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid

Conditions
ConditionsYield
Stage #1: 2,2-bis(hydroxymethyl)propionic acid With toluene-4-sulfonic acid In toluene for 0.166667h; Reflux;
Stage #2: 2,2-dimethoxy-propane In toluene for 2h;
90%
2,2-bis(hydroxymethyl)propionic acid
4767-03-7

2,2-bis(hydroxymethyl)propionic acid

benzyl bromide
100-39-0

benzyl bromide

benzyl 2,2-bis(hydroxylmethyl)propionate
179388-73-9

benzyl 2,2-bis(hydroxylmethyl)propionate

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide89%
With potassium hydroxide In N,N-dimethyl-formamide at 100℃;89%
With potassium carbonate In N,N-dimethyl-formamide for 7h; Cooling with ice;80%

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