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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Dimethyl Benzylmalonate with high purity

Cas:52267-39-7

Min.Order:1 Kilogram

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Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:

Benzyl Methyl Malonate

Cas:52267-39-7

Min.Order:1 Kilogram

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

Dimethyl benzylmalonate

Cas:52267-39-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

BENZYL METHYL MALONATE CAS NO 52267-39-7

Cas:52267-39-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 52267-39-7 with competitive price

Cas:52267-39-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:1 Gram

FOB Price: $109.0

Type:Trading Company

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

52267-39-7 BENZYL METHYL MALONATE

Cas:52267-39-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Dimethyl benzylmalonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Manufacturers

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ Benzyl methyl malonate /Manufacturer in China

Cas:52267-39-7

Min.Order:0 Metric Ton

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Type:Lab/Research institutions

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Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

Benzyl methyl malonate CAS 52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Dimethyl benzylmalonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Dimethyl Benzylmalonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Manufacturers

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Trading Company

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzyl Methyl Malonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

BENZYL METHYL MALONATE CAS No.52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

Dimethyl benzylmalonate cas 52267-39-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Dimethyl benzylmalonate cas 52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Other

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Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5g Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

Benzyl Methyl Malonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Trading Company

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Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Dimethyl benzylmalonate 52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Trading Company

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Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Dimethyl benzylmalonate 52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Trading Company

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LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

BENZYL METHYL MALONATE

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Trading Company

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Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

Benzyl methyl malonate

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Dimethylbenzylmalonate

Cas:52267-39-7

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

BENZYL METHYL MALONATE

Cas:52267-39-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

Benzyl Methyl Malonate

Cas:52267-39-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zhengzhou Kingorgchem Chemical Technology Co., Ltd.

1. Subsidiary of Institute of Chemistry, Henan Academy of Sciences, national research platform;2. About 30 years’ experience in this field since 1983;3. An experienced R&D team consisting of Doctors and Masters;4. Various types of analytical instrume

ISO 9001 National Research Platform CAS No. 52267-39-7

Cas:52267-39-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

malonic acid monobenzyl ester
40204-26-0

malonic acid monobenzyl ester

methyl chloroformate
79-22-1

methyl chloroformate

A

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

B

CO2

CO2

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 4℃; for 0.5h;A 100%
B n/a
Malonic acid monomethyl ester
16695-14-0

Malonic acid monomethyl ester

benzyl chloroformate
501-53-1

benzyl chloroformate

A

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

B

CO2

CO2

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 4℃; for 0.5h;A 99%
B n/a
monomethyl monopotassium malonate
38330-80-2

monomethyl monopotassium malonate

benzyl bromide
100-39-0

benzyl bromide

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 22h;97%
methanol
67-56-1

methanol

C10H7IO2
1416169-71-5

C10H7IO2

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate In water; acetonitrile at 20℃; for 0.0833333h;94%
malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

benzyl alcohol
100-51-6

benzyl alcohol

A

malonic acid dibenzyl ester
15014-25-2

malonic acid dibenzyl ester

B

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Conditions
ConditionsYield
at 140 - 170℃; Transesterification;A 9%
B 86%
methoxycarbonylketene
89238-09-5

methoxycarbonylketene

benzyl alcohol
100-51-6

benzyl alcohol

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Conditions
ConditionsYield
80%
benzyl (E)-β-methoxyacrylate
1621424-09-6

benzyl (E)-β-methoxyacrylate

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Conditions
ConditionsYield
With methanol; silver(I) acetate; palladium diacetate; sodium nitrite at 80℃; for 24h; Inert atmosphere;60%
benzylacrylate
2495-35-4

benzylacrylate

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: palladium diacetate; silver(I) acetate; sodium nitrite / 8 h / 25 °C / Inert atmosphere
2: methanol; palladium diacetate; silver(I) acetate; sodium nitrite / 24 h / 80 °C / Inert atmosphere
View Scheme
methanol
67-56-1

methanol

benzylacrylate
2495-35-4

benzylacrylate

A

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

B

benzyl (E)-β-methoxyacrylate
1621424-09-6

benzyl (E)-β-methoxyacrylate

Conditions
ConditionsYield
With silver(I) acetate; palladium diacetate; sodium nitrite at 110℃; for 6h;A 14 %Spectr.
B 80 %Spectr.
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

2-[(Z)-Hydroxyimino]-malonic acid benzyl ester methyl ester
118283-56-0

2-[(Z)-Hydroxyimino]-malonic acid benzyl ester methyl ester

Conditions
ConditionsYield
With acetic acid; sodium nitrite In water Ambient temperature;95.4%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

N-methyl-N-phenylthiocarbamoyl fluoride

N-methyl-N-phenylthiocarbamoyl fluoride

1-benzyl 3-methyl 2-(methyl(phenyl)carbamothioyl)malonate

1-benzyl 3-methyl 2-(methyl(phenyl)carbamothioyl)malonate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 80℃; for 12h;95%
(1S,3R,4S,6R,8R,9R)-6-methyl-12-methylene-10-azatetracyclo[7.2.2.03,8.04,10]tridecan-13-one
1260224-12-1

(1S,3R,4S,6R,8R,9R)-6-methyl-12-methylene-10-azatetracyclo[7.2.2.03,8.04,10]tridecan-13-one

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

α-{(1S,3R,4S,6S,8R,9R,10R)-6-methyl-13-oxo-10-azatetracyclo[7.2.2.03,8.04,10]tridecan-12-yl}methyl malonic acid benzyl methyl ester
1422437-40-8

α-{(1S,3R,4S,6S,8R,9R,10R)-6-methyl-13-oxo-10-azatetracyclo[7.2.2.03,8.04,10]tridecan-12-yl}methyl malonic acid benzyl methyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃;91.3%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

4-phenyl-1-(pyrrolidin-1-yl)butan-1-one
100420-10-8

4-phenyl-1-(pyrrolidin-1-yl)butan-1-one

1-benzyl 3-methyl 2-[1-oxo-4-phenyl-1-(pyrrolidin-1-yl)butan-2-yl]malonate

1-benzyl 3-methyl 2-[1-oxo-4-phenyl-1-(pyrrolidin-1-yl)butan-2-yl]malonate

Conditions
ConditionsYield
Stage #1: 4-phenyl-1-(pyrrolidin-1-yl)butan-1-one With 2-iodopyridine; trifluoromethylsulfonic anhydride In dichloromethane at 0℃; for 0.25h; Inert atmosphere;
Stage #2: With 2,6-lutidine N-oxide In dichloromethane at 0℃; for 0.0166667h; Inert atmosphere;
Stage #3: benzyl methyl malonate With sodium hydride In tetrahydrofuran; dichloromethane at 0 - 25℃; for 1h; Inert atmosphere; chemoselective reaction;
89%
Di-tert-butyl acetylenedicarboxylate
66086-33-7

Di-tert-butyl acetylenedicarboxylate

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

trans-1-benzyl 2,3-di-tert-butyl 1-methyl cyclopropane-1,1,2,3-tetracarboxylate

trans-1-benzyl 2,3-di-tert-butyl 1-methyl cyclopropane-1,1,2,3-tetracarboxylate

Conditions
ConditionsYield
With triphenyl-arsane In ethanol at 0 - 20℃; for 240h;85.9%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

1-benzyl 3-methyl 2-bromomalonate
132873-63-3

1-benzyl 3-methyl 2-bromomalonate

Conditions
ConditionsYield
With bromine In tetrachloromethane85%
With bromine In tetrachloromethane Irradiation;68%
Stage #1: benzyl methyl malonate With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at -78 - 20℃; for 1h; Inert atmosphere;
Stage #2: With carbon tetrabromide In tetrahydrofuran at -78℃; for 3h; Inert atmosphere;
60%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

allyl alcohol
107-18-6

allyl alcohol

A

1-benzyl 3-methyl 2,2-diallylmalonate

1-benzyl 3-methyl 2,2-diallylmalonate

B

1-benzyl 3-methyl 2-allylmalonate

1-benzyl 3-methyl 2-allylmalonate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; nickel(II) bromide trihydrate; tetrabutylammonium acetate; zinc In N,N-dimethyl acetamide at 50℃; for 66h; Inert atmosphere;A 14%
B 84%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

propargyl bromide
106-96-7

propargyl bromide

methyl benzyl 2,2-diprop-2-ynylmalonate
162107-25-7

methyl benzyl 2,2-diprop-2-ynylmalonate

Conditions
ConditionsYield
With potassium carbonate In acetone for 65h; Heating;83%
(S)-2-chloro-1-(2-ethyl-8-methoxyquinolin-5-yl)propan-1-one
1421045-80-8

(S)-2-chloro-1-(2-ethyl-8-methoxyquinolin-5-yl)propan-1-one

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

1-benzyl 3-methyl 2-[1-(2-ethyl-8-methoxyquinolin-5-yl)-1-oxopropan-2-yl]malonate

1-benzyl 3-methyl 2-[1-(2-ethyl-8-methoxyquinolin-5-yl)-1-oxopropan-2-yl]malonate

Conditions
ConditionsYield
Stage #1: (S)-2-chloro-1-(2-ethyl-8-methoxyquinolin-5-yl)propan-1-one; benzyl methyl malonate With sodium hydride In N,N-dimethyl-formamide at 20℃; for 14h; Inert atmosphere;
Stage #2: Inert atmosphere;
83%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

(S)-4-[(E)-6-(3-Formyl-phenyl)-hex-3-enyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

(S)-4-[(E)-6-(3-Formyl-phenyl)-hex-3-enyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

2-[1-{3-[(E)-6-((S)-3-tert-Butoxycarbonyl-2,2-dimethyl-oxazolidin-4-yl)-hex-3-enyl]-phenyl}-meth-(Z)-ylidene]-malonic acid benzyl ester methyl ester

2-[1-{3-[(E)-6-((S)-3-tert-Butoxycarbonyl-2,2-dimethyl-oxazolidin-4-yl)-hex-3-enyl]-phenyl}-meth-(Z)-ylidene]-malonic acid benzyl ester methyl ester

Conditions
ConditionsYield
With piperidine; benzoic acid In toluene for 6h; Heating;82%
dimethoxyacetaldehyde
51673-84-8

dimethoxyacetaldehyde

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

2-[2,2-Dimethoxy-eth-(Z)-ylidene]-malonic acid benzyl ester methyl ester
161681-84-1

2-[2,2-Dimethoxy-eth-(Z)-ylidene]-malonic acid benzyl ester methyl ester

Conditions
ConditionsYield
With piperidine In toluene Heating;82%
methyl 5-acetamido-2,6-anhydro-4-O-benzoyl-7-O-(tert-butyldimethylsilyl)-3,5-dideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate
1171908-44-3

methyl 5-acetamido-2,6-anhydro-4-O-benzoyl-7-O-(tert-butyldimethylsilyl)-3,5-dideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

methyl 5-acetamido-2,6-anhydro-4-C-[(benzyloxycarbonyl)(methoxycarbonyl)methyl]-7-O-(tert-butyldimethylsilyl)-3,4,5-trideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate
1228377-57-8

methyl 5-acetamido-2,6-anhydro-4-C-[(benzyloxycarbonyl)(methoxycarbonyl)methyl]-7-O-(tert-butyldimethylsilyl)-3,4,5-trideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tributylphosphine; sodium In tetrahydrofuran; mineral oil at 60℃; for 18h; Inert atmosphere; stereoselective reaction;80%
methyl 5-acetamido-2,6-anhydro-4-O-benzoyl-7-O-(tert-butyldimethylsilyl)-3,5-dideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate
1171908-44-3

methyl 5-acetamido-2,6-anhydro-4-O-benzoyl-7-O-(tert-butyldimethylsilyl)-3,5-dideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-2-enoate

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

methyl 5-acetamido-2,6-anhydro-2-C-[(benzyloxycarbonyl)(methoxycarbonyl)methyl]-7-O-(tert-butyldimethylsilyl)-3,4,5-trideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-3-enoate
1228377-56-7

methyl 5-acetamido-2,6-anhydro-2-C-[(benzyloxycarbonyl)(methoxycarbonyl)methyl]-7-O-(tert-butyldimethylsilyl)-3,4,5-trideoxy-8,9-O-isopropylidene-D-glycero-D-galacto-non-3-enoate

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; sodium; 1,4-di(diphenylphosphino)-butane In tetrahydrofuran; mineral oil at 60℃; for 2h; Inert atmosphere; stereoselective reaction;75%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

methyl (S)-5-(3-hydroxybut-1-yn-1-yl)-1-methyl-1H-pyrazole-4-carboxylate

methyl (S)-5-(3-hydroxybut-1-yn-1-yl)-1-methyl-1H-pyrazole-4-carboxylate

1-benzyl 3-methyl 2-((S)-4-(4-(methoxycarbonyl)-1-methyl-1H-pyrazol-5-yl)but-3-yn-2-yl)malonate

1-benzyl 3-methyl 2-((S)-4-(4-(methoxycarbonyl)-1-methyl-1H-pyrazol-5-yl)but-3-yn-2-yl)malonate

Conditions
ConditionsYield
Stage #1: methyl (S)-5-(3-hydroxybut-1-yn-1-yl)-1-methyl-1H-pyrazole-4-carboxylate With methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 20℃; for 1.75h;
Stage #2: benzyl methyl malonate With cesium fluoride In 1,4-dioxane at 80℃; for 16h;
74%
formaldehyd
50-00-0

formaldehyd

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

N-benzyl-3-amino-2-cyclohexen-1-one
41609-04-5

N-benzyl-3-amino-2-cyclohexen-1-one

1-benzyl 3-methyl 2-((2-(benzylamino)-6-oxocyclohex-1-en-1-yl)methyl)malonate

1-benzyl 3-methyl 2-((2-(benzylamino)-6-oxocyclohex-1-en-1-yl)methyl)malonate

Conditions
ConditionsYield
With lithium perchlorate; acetic anhydride In acetonitrile at 60℃; Sealed tube;73%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

ethyl 2-bromomethyl-2-propenoate
17435-72-2

ethyl 2-bromomethyl-2-propenoate

4-Benzyloxycarbonyl-2,6-bis(ethoxycarbonyl)-4-methoxycarbonyl-1,6-heptadiene

4-Benzyloxycarbonyl-2,6-bis(ethoxycarbonyl)-4-methoxycarbonyl-1,6-heptadiene

Conditions
ConditionsYield
In water; acetonitrile72.4%
isochromane
493-05-0

isochromane

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

1-benzyl 3-methyl 2-(isochroman-1-yl)malonate
1246668-97-2

1-benzyl 3-methyl 2-(isochroman-1-yl)malonate

Conditions
ConditionsYield
With iron(II) triflate; 2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate In dichloromethane at 20℃; Inert atmosphere;72%
1-(2-nitro-vinyl)-naphthalen-2-ol
82843-06-9

1-(2-nitro-vinyl)-naphthalen-2-ol

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

2-benzyl 2-methyl 1-(nitromethyl)naphtho[2,1-b]furan-2,2(1H)-dicarboxylate

2-benzyl 2-methyl 1-(nitromethyl)naphtho[2,1-b]furan-2,2(1H)-dicarboxylate

Conditions
ConditionsYield
With tert.-butylhydroperoxide; iodine; sodium hydrogencarbonate In tetrahydrofuran; decane at 30℃; for 24h;67%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

(S)-4-[(E)-5-(2-Formyl-phenyl)-pent-2-enyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

(S)-4-[(E)-5-(2-Formyl-phenyl)-pent-2-enyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

2-[1-{2-[(E)-5-((S)-3-tert-Butoxycarbonyl-2,2-dimethyl-oxazolidin-4-yl)-pent-3-enyl]-phenyl}-meth-(E)-ylidene]-malonic acid benzyl ester methyl ester

2-[1-{2-[(E)-5-((S)-3-tert-Butoxycarbonyl-2,2-dimethyl-oxazolidin-4-yl)-pent-3-enyl]-phenyl}-meth-(E)-ylidene]-malonic acid benzyl ester methyl ester

Conditions
ConditionsYield
With piperidine; benzoic acid In toluene for 6h; Heating;66%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

N-benzyloxymethyl-3'-O-(tert-butyldimethylsilyl)-5'-deoxy-5'-iodothymidine

N-benzyloxymethyl-3'-O-(tert-butyldimethylsilyl)-5'-deoxy-5'-iodothymidine

C-(N3-benzyloxymethyl-3'-O-(tert-butyldimethylsilyl)-5'-deoxythymidin-5'-yl)benzyl methyl malonate

C-(N3-benzyloxymethyl-3'-O-(tert-butyldimethylsilyl)-5'-deoxythymidin-5'-yl)benzyl methyl malonate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil66%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

1-amino-2-propene
107-11-9

1-amino-2-propene

A

1-benzyl 3-methyl 2,2-diallylmalonate

1-benzyl 3-methyl 2,2-diallylmalonate

B

1-benzyl 3-methyl 2-allylmalonate

1-benzyl 3-methyl 2-allylmalonate

Conditions
ConditionsYield
With nickel(II) bromide trihydrate; 1,4-di(diphenylphosphino)-butane; zinc In N,N-dimethyl-formamide at 80℃; for 22h; Inert atmosphere;A 20%
B 64%
benzyl methyl malonate
52267-39-7

benzyl methyl malonate

Methyl-benzyl-hydroxymalonat

Methyl-benzyl-hydroxymalonat

Conditions
ConditionsYield
With cerium; ammonium nitrate; oxygen In methanol for 6h; Ambient temperature;62%
3-Phenylpropenol
104-54-1

3-Phenylpropenol

benzyl methyl malonate
52267-39-7

benzyl methyl malonate

1-benzyl 3-methyl 2-(cinnamyloxy)malonate

1-benzyl 3-methyl 2-(cinnamyloxy)malonate

Conditions
ConditionsYield
Stage #1: benzyl methyl malonate With 4-toluenesulfonyl azide; triethylamine In acetonitrile at 0 - 20℃;
Stage #2: 3-Phenylpropenol With rhodium(II) acetate dimer In dichloromethane at 0 - 20℃; Inert atmosphere;
59%

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