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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4-Bromoindole / LIDE PHARMA- Factory supply / Best price

Cas:52488-36-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4-Bromoindole Manufacturer/High quality/Best price/In stock

Cas:52488-36-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 4-Bromoindole Cas 52488-36-5 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Liquid Storage:0-6°C Package:250kg/drum or as you required Applica

China chemical supplier 4-Bromoindole Cas 52488-36-5 with top quality low price

Cas:52488-36-5

Min.Order:1 Kilogram

FOB Price: $30.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Bromoindole

Cas:52488-36-5

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Bromoindole

Cas:52488-36-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:4-Bromoindole CAS NO: 52488-36-5 Grade:Medical scientific research and export Molecular formula:C7H5BrN2 Molecular weight:197.032 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability

4-Bromoindole/cas:52488-36-5/Raw material spot

Cas:52488-36-5

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFUCHEM-4-Bromoindole

Cas:52488-36-5

Min.Order:1 Kilogram

FOB Price: $2000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 52488-36-5 with fast shipping

Cas:52488-36-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name 4-Bromoindole / 4-bromo-1H-indole CAS 52488-36-5 MF C8H6BrN Type Pharmaceutical Intermediates Content Min 98.0% A

4-Bromoindole CAS: 52488-36-5

Cas:52488-36-5

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

high quality 4-Bromoindole/4-Bromo-1H-indole CAS No.:52488-36-5

Cas:52488-36-5

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Bromoindole 52488-36-5

Cas:52488-36-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

4-Bromoindole with CAS:52488-36-5

Cas:52488-36-5

Min.Order:1 Kilogram

FOB Price: $24.0 / 30.0

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Bromo Indole

Cas:52488-36-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4-Bromoindole

Cas:52488-36-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-Bromoindole CAS52488-36-5

Cas:52488-36-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-bromoindole

Cas:52488-36-5

Min.Order:0

Negotiable

Type:Manufacturers

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-BROMOINDOLE

Cas:52488-36-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Bromoindole

Cas:52488-36-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-bromo-1H-indole

Cas:52488-36-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

4-Bromoindole

Cas:52488-36-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-Bromoindole

Cas:52488-36-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 4-Bromoindole CAS No.:52488-36-5 Molecule Formula:C7H5BrN2 Molecule Weight:197.03 Purity: 98.0% Package: 200kg/drum Description:Light yellow liquid Manufacture Standards:Enterprise Standard TESTING IT

Best Quality 4-Bromoindole

Cas:52488-36-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-Bromoindole

Cas:52488-36-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

4-Bromoindole Basic information Product Name: 4-Bromoindole Synonyms: 4-BROMO-1H-INDOLE,4-BROMOINDOLE;4-BROMO-1H-INDAZOLE;4-BROMO-INDOLE pure;4-Bromoindole ,95%;4-Bromo-1H-indole , TECH;1H-Indole,4-broMo-;4-Bromoindole 96%;4-BROMOINDOLE CAS:

4-Bromoindole

Cas:52488-36-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-Bromoindole

Cas:52488-36-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-Bromoindole

Cas:52488-36-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-Bromoindole

Cas:52488-36-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

BEST PRICE/4-Bromoindole CAS NO.52488-36-5

Cas:52488-36-5

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

4-Bromoindole

Cas:52488-36-5

Min.Order:0

Negotiable

Type:Other

inquiry

Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

4-Bromoindole

Cas:52488-36-5

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Synthetic route

4-bromo-1-[(4-methylphenyl)sulfonyl]-1H-indole
90481-72-4

4-bromo-1-[(4-methylphenyl)sulfonyl]-1H-indole

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium hydroxide In methanol for 12h; Heating;98%
4-bromo-1-(trifluoromethylsulfonyl)indole
1180007-97-9

4-bromo-1-(trifluoromethylsulfonyl)indole

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium hydroxide In methanol; water at 100℃; for 12h;96%
4-bromo-2,3-dihydro-1H-indole
86626-38-2

4-bromo-2,3-dihydro-1H-indole

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium carbonate In ethyl acetate at 120℃; for 24h; Sealed tube; Green chemistry;95%
With TEMPOL; oxygen; copper(l) chloride at 50 - 60℃; for 4.5h; Inert atmosphere;95%
With oxygen; sodium t-butanolate In dimethyl sulfoxide at 60℃; under 760.051 Torr; for 4h;48%
1-(4-bromo-1H-indol-1-yl)-2,2-dimethylpropan-1-one
1196981-04-0

1-(4-bromo-1H-indol-1-yl)-2,2-dimethylpropan-1-one

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With water; 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran for 3h; Reflux;94%
4-bromo-1-methoxycarbonylindole
101909-45-9

4-bromo-1-methoxycarbonylindole

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium hydroxide In methanol for 1h; Heating;88.5%
1-bromo-2-ethenyl-3-nitrobenzene
90481-68-8

1-bromo-2-ethenyl-3-nitrobenzene

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With carbon monoxide; triphenylphosphine; palladium diacetate In acetonitrile under 3040 Torr; for 15h; Heating;84%
With carbon monoxide; triphenylphosphine; palladium diacetate In acetonitrile under 3040 Torr; for 15h; Product distribution; Heating; other catalysts, phosphine, bases, solvents; palladium-catalyzed reductive heteroannulation of 2-nitrostyrenes in the presence of CO;84%
Multi-step reaction with 2 steps
1: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
2: 46.3 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 22 h / 100 °C / sealed tube
View Scheme
Multi-step reaction with 4 steps
1: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
2: pyridine / 0.33 h / Heating
3: 76.7 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 18 h / Heating
4: 98 percent / 20percent aq. NaOH / methanol / 12 h / Heating
View Scheme
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

1-bromo-2-ethenyl-3-nitrobenzene
90481-68-8

1-bromo-2-ethenyl-3-nitrobenzene

A

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

B

methyl (3-bromo-2-vinylphenyl)carbamate

methyl (3-bromo-2-vinylphenyl)carbamate

Conditions
ConditionsYield
With 1,3-bis-(diphenylphosphino)propane; palladium diacetate In N,N-dimethyl-formamide under 3040 Torr; for 22h; Heating;A 76%
B 17%
N-(3-bromo-2-(2-(trimethylsilyl)ethynyl)phenyl)-2-hydroxy-2-methylpropanamide
1244651-69-1

N-(3-bromo-2-(2-(trimethylsilyl)ethynyl)phenyl)-2-hydroxy-2-methylpropanamide

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl-formamide at 140℃; for 56h; Inert atmosphere;75%
With sodium hydroxide In N,N-dimethyl-formamide at 140℃; for 5h; Inert atmosphere;75%
1H-indol-4-yl trifluoromethanesulfonate

1H-indol-4-yl trifluoromethanesulfonate

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); t-BuBrettPhos; potassium bromide In 1,4-dioxane at 130℃; for 16h; Inert atmosphere;74%
4-bromo-2,3-dihydro-1H-indole
86626-38-2

4-bromo-2,3-dihydro-1H-indole

nitrobenzene
98-95-3

nitrobenzene

A

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

B

aniline
62-53-3

aniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 70%
B 74%
2-(2-amino-6-bromophenyl)ethan-1-ol
109277-82-9

2-(2-amino-6-bromophenyl)ethan-1-ol

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
tris(triphenylphosphine)ruthenium(II) chloride In toluene for 6h; Heating;73%
tris(triphenylphosphine)ruthenium(II) chloride In toluene for 6h; Rate constant; Heating;73%
With C72H79O35Ru4; o-phenylenebis(diphenylphosphine); oxygen In toluene at 130℃; for 4h; Inert atmosphere;71%
[(E)-2-(2-Bromo-6-nitro-phenyl)-vinyl]-dimethyl-amine
105205-47-8

[(E)-2-(2-Bromo-6-nitro-phenyl)-vinyl]-dimethyl-amine

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With zinc In acetic acid at 85℃; for 2h;70%
With acetic acid; zinc In methanol; dichloromethane Heating;67%
1-[(E)-2-(2-Bromo-6-nitro-phenyl)-vinyl]-pyrrolidine

1-[(E)-2-(2-Bromo-6-nitro-phenyl)-vinyl]-pyrrolidine

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With zinc In acetic acid Reduction; cyclization;70%
4-bromo-1H-indole-3-carboxylic acid methyl ester
101909-43-7

4-bromo-1H-indole-3-carboxylic acid methyl ester

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium hydroxide In methanol for 1.5h; Heating;69.1%
With sodium hydroxide In methanol for 1.5h; Heating;60.5%
4-bromo-2,3-dihydro-1H-indole
86626-38-2

4-bromo-2,3-dihydro-1H-indole

4-chlorobenzonitrile
100-00-5

4-chlorobenzonitrile

A

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

B

4-chloro-aniline
106-47-8

4-chloro-aniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 53%
B 52%
3-bromo-2-ethenylaniline
90481-69-9

3-bromo-2-ethenylaniline

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With dichloro bis(acetonitrile) palladium(II); p-benzoquinone; lithium chloride In tetrahydrofuran at 100℃; for 22h; sealed tube;46.3%
Multi-step reaction with 3 steps
1: pyridine / 0.33 h / Heating
2: 76.7 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 18 h / Heating
3: 98 percent / 20percent aq. NaOH / methanol / 12 h / Heating
View Scheme
4-bromo-1H-indole-2-carboxylic acid
16732-64-2

4-bromo-1H-indole-2-carboxylic acid

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With quinoline; copper(I) bromide at 250℃;
(2-Bromo-6-nitro-phenyl)-acetaldehyde
85355-50-6

(2-Bromo-6-nitro-phenyl)-acetaldehyde

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium acetate; iron; acetic acid In ethanol; water for 2h; Heating; Yield given;
Acetic acid 2-(2-bromo-6-nitro-phenyl)-1-chloro-ethyl ester
85355-40-4

Acetic acid 2-(2-bromo-6-nitro-phenyl)-1-chloro-ethyl ester

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
With sodium acetate; iron; acetic acid In ethanol; water for 2h; Heating;
2-bromo-6-nitrotoluene
55289-35-5

2-bromo-6-nitrotoluene

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Stage #1: 2-bromo-6-nitrotoluene; N,N-dimethyl-formamide dimethyl acetal With pyrrolidine In N,N-dimethyl-formamide at 110℃; for 5h;
Stage #2: With acetic acid; zinc at 85℃; for 3h;
25.2 g
3-nitro-o-tolylamine
603-83-8

3-nitro-o-tolylamine

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aq. HBr / 0.33 h / Heating
1.2: aq. NaNO2 / 0.25 h / 0 - 5 °C
1.3: 90 percent / CuBr; aq. HBr / 0.33 h / 100 °C
2.1: pyrrolidine / dimethylformamide / 5 h / 110 °C
2.2: 25.2 g / aq. HOAc; zinc / 3 h / 85 °C
View Scheme
Multi-step reaction with 6 steps
2: 98 percent / Br2, benzoyl peroxide / CCl4 / 14 h / Heating; Irradiation
3: CHCl3 / 0.17 h / Heating
4: 85.1 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
5: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
6: 46.3 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 22 h / 100 °C / sealed tube
View Scheme
Multi-step reaction with 8 steps
2: 98 percent / Br2, benzoyl peroxide / CCl4 / 14 h / Heating; Irradiation
3: CHCl3 / 0.17 h / Heating
4: 85.1 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
5: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
6: pyridine / 0.33 h / Heating
7: 76.7 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 18 h / Heating
8: 98 percent / 20percent aq. NaOH / methanol / 12 h / Heating
View Scheme
2-bromo-6-nitrotoluene
55289-35-5

2-bromo-6-nitrotoluene

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CuI; DMF / 0.33 h / 180 °C / 6000.6 - 7500.75 Torr / microwave irradiation
2: 67 percent / Zn; AcOH / methanol; CH2Cl2 / Heating
View Scheme
Multi-step reaction with 2 steps
1: 1.) Triton B, 2.) Zn, CaCl2 / 1.) Me2SO, 95 deg C, 1 h, 2.) H2O, reflux
2: 73 percent / RuCl2(PPh3)3 / toluene / 6 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: pyrrolidine / dimethylformamide / 110 °C
2: 70 percent / Zn / acetic acid / 2 h / 85 °C
View Scheme
3-methoxycarbonylindole
942-24-5

3-methoxycarbonylindole

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: thallium(III) trifluoroacetate / trifluoroacetic acid / 2 h / 20 °C
1.2: 63 percent / CuBr2 / dimethylformamide / 1 h / 120 °C
2.1: 69.1 percent / aq. NaOH / methanol / 1.5 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 1.) TTFA, 2.) CuBr2 / 1.) TFA, room temp., 2 h; 2.) DMF, 120 deg C, 1 h
2: 60.5 percent / 40percent NaOH / methanol / 1.5 h / Heating
View Scheme
2-bromo-6-nitroaniline
59255-95-7

2-bromo-6-nitroaniline

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: H2SO4, isoamyl nitrite / ethanol / 1 h / 0 °C
2: LiCl, HCl, CuCl*2H2O / acetone; H2O / 1.) 2 h, 3 to 10 deg C, 2.) 2 h, room temp., 3.) 2 h, room temp.
3: Fe, HOAc, sodium acetate dihydrate / ethanol; H2O / 2 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: H2SO4, isoamyl nitrite / ethanol / 1 h / 0 °C
2: LiCl, HCl, CuCl*2H2O / acetone; H2O / 1.) 2 h, 3 to 10 deg C, 2.) 2 h, room temp., 3.) 2 h, room temp.
3: Fe, HOAc, sodium acetate dihydrate / ethanol; H2O / 2 h / Heating
View Scheme
2-Bromo-6-nitro-benzenediazonium; hydrogen sulfate
85355-33-5

2-Bromo-6-nitro-benzenediazonium; hydrogen sulfate

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LiCl, HCl, CuCl*2H2O / acetone; H2O / 1.) 2 h, 3 to 10 deg C, 2.) 2 h, room temp., 3.) 2 h, room temp.
2: Fe, HOAc, sodium acetate dihydrate / ethanol; H2O / 2 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: LiCl, HCl, CuCl*2H2O / acetone; H2O / 1.) 2 h, 3 to 10 deg C, 2.) 2 h, room temp., 3.) 2 h, room temp.
2: Fe, HOAc, sodium acetate dihydrate / ethanol; H2O / 2 h / Heating
View Scheme
3-bromo-2-(bromomethyl)-1-nitrobenzene
58579-54-7

3-bromo-2-(bromomethyl)-1-nitrobenzene

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: CHCl3 / 0.17 h / Heating
2: 85.1 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
3: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
4: 46.3 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 22 h / 100 °C / sealed tube
View Scheme
Multi-step reaction with 6 steps
1: CHCl3 / 0.17 h / Heating
2: 85.1 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
3: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
4: pyridine / 0.33 h / Heating
5: 76.7 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 18 h / Heating
6: 98 percent / 20percent aq. NaOH / methanol / 12 h / Heating
View Scheme
N-tosyl-3-bromo-2-ethenylaniline
90481-71-3

N-tosyl-3-bromo-2-ethenylaniline

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 76.7 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 18 h / Heating
2: 98 percent / 20percent aq. NaOH / methanol / 12 h / Heating
View Scheme
(2-Bromo-6-nitro-benzyl)-triphenyl-phosphonium; bromide
90481-67-7

(2-Bromo-6-nitro-benzyl)-triphenyl-phosphonium; bromide

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 85.1 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
2: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
3: 46.3 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 22 h / 100 °C / sealed tube
View Scheme
Multi-step reaction with 5 steps
1: 85.1 percent / Et3N / CH2Cl2 / 1 h / Ambient temperature
2: 96.6 percent / Fe / acetic acid; ethanol / 5 h / Heating
3: pyridine / 0.33 h / Heating
4: 76.7 percent / p-benzoquinone, LiCl, PdCl2(CH3CN)2 / tetrahydrofuran / 18 h / Heating
5: 98 percent / 20percent aq. NaOH / methanol / 12 h / Heating
View Scheme
2-(2-bromo-6-nitrophenyl)ethan-1-ol
118665-02-4

2-(2-bromo-6-nitrophenyl)ethan-1-ol

4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Zn/CaCl2/H2O / ethanol / Heating
2: 73 percent / RuCl2(PPh3)3 / toluene / 6 h / Heating
View Scheme
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

4-bromo-1H-indole-3-carbaldehyde
98600-34-1

4-bromo-1H-indole-3-carbaldehyde

Conditions
ConditionsYield
With trichlorophosphate at 20℃; for 1h; Vilsmeier-Hack formylation;100%
Stage #1: N,N-dimethyl-formamide With trichlorophosphate Cooling with ice;
Stage #2: 4-bromo-1H-indole In N,N-dimethyl-formamide at 20℃; Cooling with ice;
Stage #3: With water; potassium hydroxide In N,N-dimethyl-formamide Reflux;
100%
Stage #1: 4-bromo-1H-indole; N,N-dimethyl-formamide With trichlorophosphate at 0 - 25℃;
Stage #2: With potassium hydroxide In water Reflux;
100%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

indole-4-boronic acid pinacol ester
388116-27-6

indole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In dimethyl sulfoxide at 90℃; for 4h;100%
With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In dimethyl sulfoxide at 90℃; for 4h;100%
With tris-(dibenzylideneacetone)dipalladium(0); potassium acetate; XPhos In 1,4-dioxane at 110℃; for 20h; Miyaura borylation; Inert atmosphere;93%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

methyl iodide
74-88-4

methyl iodide

4-bromo-1-methyl-1H-indole
590417-55-3

4-bromo-1-methyl-1H-indole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 3h;100%
Stage #1: 4-bromo-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.5h; Schlenk technique;
Stage #2: methyl iodide In tetrahydrofuran at 0 - 20℃; Schlenk technique;
100%
With sodium hydride In tetrahydrofuran at 20℃; for 4h;98%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-bromoindole-1-carboxylic acid tert-butyl ester
676448-17-2

4-bromoindole-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With dmap In tetrahydrofuran for 0.25h;100%
In dichloromethane at 20℃; for 8h;99%
With dmap In dichloromethane at 20℃; for 8h; Inert atmosphere;98%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

2-(tert-butyldimethylsilyloxy)ethyl bromide
86864-60-0

2-(tert-butyldimethylsilyloxy)ethyl bromide

4-bromo-1-[3-(tert-butyldimethylsilyloxy)prop-1-yl]-1H-indole
603305-12-0

4-bromo-1-[3-(tert-butyldimethylsilyloxy)prop-1-yl]-1H-indole

Conditions
ConditionsYield
Stage #1: 4-bromo-1H-indole With sodium hydride In DMF (N,N-dimethyl-formamide)
Stage #2: 2-(tert-butyldimethylsilyloxy)ethyl bromide In DMF (N,N-dimethyl-formamide) at 0 - 20℃; for 1h;
100%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

thiophenol
108-98-5

thiophenol

4-bromo-3-(phenylthio)-1H-indole
945000-87-3

4-bromo-3-(phenylthio)-1H-indole

Conditions
ConditionsYield
With iodine; potassium iodide In ethanol; water at 45℃; for 12.0833h;99.5%
With iodine; potassium iodide In ethanol; water at 20 - 60℃;92%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-4-bromobenzylamine
479423-30-8

N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-4-bromobenzylamine

C20H20Br2N2O2

C20H20Br2N2O2

Conditions
ConditionsYield
With potassium fluoride; C46H34I4O6 In m-xylene at 20℃; for 12h; Friedel-Crafts Alkylation; Schlenk technique; enantioselective reaction;99%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

tert-butyl N-(phenyl(phenylsulfonyl)methyl)carbamate
155396-71-7

tert-butyl N-(phenyl(phenylsulfonyl)methyl)carbamate

4-bromo-3-[phenyl(phenylsulfonyl)methyl]-1H-indole

4-bromo-3-[phenyl(phenylsulfonyl)methyl]-1H-indole

Conditions
ConditionsYield
With dipotassium peroxodisulfate In toluene at 20℃; for 48h; Friedel-Crafts Alkylation; Inert atmosphere; Schlenk technique; regioselective reaction;99%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

ethanol
64-17-5

ethanol

carbon monoxide
201230-82-2

carbon monoxide

ethyl indole-4-carboxylate
50614-84-1

ethyl indole-4-carboxylate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; bis(benzonitrile)palladium(II) dichloride; triethylamine at 130℃; under 18751.5 Torr; for 20h;98%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

1-Bromopentane
110-53-2

1-Bromopentane

4-bromo-1-pentyl-1H-indole
912568-78-6

4-bromo-1-pentyl-1H-indole

Conditions
ConditionsYield
In N,N-dimethyl-formamide; mineral oil98%
Stage #1: 4-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 1-Bromopentane In N,N-dimethyl-formamide at 0 - 20℃; for 6h;
98%
Stage #1: 4-bromo-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 1-Bromopentane In N,N-dimethyl-formamide at 0 - 20℃; for 6h;
98%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

trifluoromethane sulfonyl chloride
421-83-0

trifluoromethane sulfonyl chloride

4-bromo-3-((trifluoromethyl)thio)-1H-indole

4-bromo-3-((trifluoromethyl)thio)-1H-indole

Conditions
ConditionsYield
With 1,2,2,3,4,4-hexamethylphosphetane 1-oxide; phenylsilane In 1,4-dioxane at 40℃; Schlenk technique; Sealed tube; Inert atmosphere;98%
With trimethylphosphane In tetrahydrofuran at -78 - 20℃; for 52h; regioselective reaction;74%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

potassium phenyltrifluoborate

potassium phenyltrifluoborate

4-phenyl-1H-indole
35577-92-5

4-phenyl-1H-indole

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate In ethanol; water at 80℃; for 4h; Suzuki-Miyaura Coupling;98%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

4-bromo-3-chloro-1H-indole
1216305-58-6

4-bromo-3-chloro-1H-indole

Conditions
ConditionsYield
With N-chloro-succinimide In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;97%
With 1,3-dichloro-5,5-dimethylhydantoin In 1,4-dioxane at 25℃; for 3h;88%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

p-toluenesulfonylhydroxylamine
1593-60-8

p-toluenesulfonylhydroxylamine

4-bromo-3-(p-tolylthio)-1H-indole

4-bromo-3-(p-tolylthio)-1H-indole

Conditions
ConditionsYield
With 1-hydroxy-pyrrolidine-2,5-dione; iodine In butan-1-ol at 120℃; for 15h; Inert atmosphere; Sealed tube; regioselective reaction;97%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

formaldehyd
50-00-0

formaldehyd

dimethyl amine
124-40-3

dimethyl amine

4-bromogramine
64258-88-4

4-bromogramine

Conditions
ConditionsYield
In water; acetic acid for 48h; Ambient temperature;96.3%
With acetic acid In water at 0 - 25℃;
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

carbon monoxide
201230-82-2

carbon monoxide

N-(1-methyl-2-phenylethyl)piperazine
14135-70-7

N-(1-methyl-2-phenylethyl)piperazine

(1H-indol-4-yl)-[4-(1-methyl-2-phenethyl)piperazin-1-yl]methanone

(1H-indol-4-yl)-[4-(1-methyl-2-phenethyl)piperazin-1-yl]methanone

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; bis(benzonitrile)palladium(II) dichloride; triethylamine In toluene at 130℃; under 18751.5 Torr; for 20h;96%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

acetyl chloride
75-36-5

acetyl chloride

1-(4-bromo-1H-indol-3-yl)ethan-1-one
195874-03-4

1-(4-bromo-1H-indol-3-yl)ethan-1-one

Conditions
ConditionsYield
With tin(IV) chloride In toluene96%
With tin(IV) chloride In toluene at 0℃; for 2h; Friedel-Crafts reaction;95%
With tin(IV) chloride In toluene at 0℃; for 2h;75%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

thiophene-2-sulfonyl chloride
16629-19-9

thiophene-2-sulfonyl chloride

4-bromo-1-(2-thienylsulfonyl)-1H-indole
1001394-83-7

4-bromo-1-(2-thienylsulfonyl)-1H-indole

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In water for 25h;96%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

4-Bromo-1-(tri-isopropylsilyl)-1H-indole
412048-44-3

4-Bromo-1-(tri-isopropylsilyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 4-bromo-1H-indole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran; mineral oil at 0 - 20℃;
96%
With sodium hydride In tetrahydrofuran at 0 - 20℃;88%
With sodium hydride In tetrahydrofuran at 20℃; Inert atmosphere; Cooling with ice;82%
With NaH In dichloromethane; N,N-dimethyl-formamide3.44 g (63%)
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

benzenesulfonyl chloride
98-09-9

benzenesulfonyl chloride

1‐(benzenesulfonyl)‐4‐bromo‐1H‐indole
412048-77-2

1‐(benzenesulfonyl)‐4‐bromo‐1H‐indole

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane at 20℃; for 1h;95%
Stage #1: 4-bromo-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: benzenesulfonyl chloride In tetrahydrofuran at 20℃; for 2h;
93%
Stage #1: 4-bromo-1H-indole With sodium hydride In tetrahydrofuran at 20℃; for 1h;
Stage #2: benzenesulfonyl chloride In tetrahydrofuran for 1h;
87%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

2-Bromoethyl methyl ether
6482-24-2

2-Bromoethyl methyl ether

4-bromo-1-(2-methoxyethyl)-1H-indole

4-bromo-1-(2-methoxyethyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 4-bromo-1H-indole With sodium hydride In 1,2-dimethoxyethane; dimethyl sulfoxide at 20℃; for 0.5h;
Stage #2: 2-Bromoethyl methyl ether In 1,2-dimethoxyethane; dimethyl sulfoxide at 20℃;
95%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

pyridine-3-sulfonyl chloride hydrochloride
42899-76-3

pyridine-3-sulfonyl chloride hydrochloride

4-bromo-1-(pyridine-3-ylsulfonyl)-1H-indole
1001394-86-0

4-bromo-1-(pyridine-3-ylsulfonyl)-1H-indole

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In water for 0.75h;95%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

benzaldehyde
100-52-7

benzaldehyde

C23H16Br2N2
1338069-91-2

C23H16Br2N2

Conditions
ConditionsYield
With C20H24Cl2N2O2Zr In ethanol at 25 - 27℃; for 0.416667h;95%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

3-pyridylboronic acid
1692-25-7

3-pyridylboronic acid

4-(pyridin-3-yl)-1H-indole
108378-92-3

4-(pyridin-3-yl)-1H-indole

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); N,N,N′,N′-tetra(diphenylphosphinomethyl)-1,2-ethylenediamine; potassium carbonate In N,N-dimethyl acetamide; butan-1-ol at 110℃; for 20h; Suzuki Coupling; Inert atmosphere;95%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

C17H18O5

C17H18O5

C24H20BrNO4

C24H20BrNO4

Conditions
ConditionsYield
In acetonitrile at 70℃; for 0.5h;95%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

bromethyl methyl ether
13057-17-5

bromethyl methyl ether

C10H10BrNO
1531618-73-1

C10H10BrNO

Conditions
ConditionsYield
Stage #1: 4-bromo-1H-indole With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil at 0℃; for 1h; Inert atmosphere;
Stage #2: bromethyl methyl ether In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil at 0 - 23℃; for 1h;
95%
4-bromo-1H-indole
52488-36-5

4-bromo-1H-indole

Benzenesulfinic acid
618-41-7

Benzenesulfinic acid

4-bromo-3-(phenylthio)-1H-indole
945000-87-3

4-bromo-3-(phenylthio)-1H-indole

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; toluene-4-sulfonic acid In 1,2-dichloro-ethane at 80℃; for 12h; regioselective reaction;95%

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