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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Butyl-3-(4-hydroxybenzoyl)benzofuran Manufacturer/High quality/Best price/In stock

Cas:52490-15-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Butyl-3-(4-Hydroxybenzoyl)Benzofuran supplier in China

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone

Cas:52490-15-0

Min.Order:1

Negotiable

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Butyl-3-(4-hydroxybenzoyl)-benzofuran

Cas:52490-15-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2-Butyl-3-(4-hydroxybenzoyl)benzofuran-

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-Butyl-3-(4-Hydroxy-Benzoyl)-Benzofuran

Cas:52490-15-0

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 52490-15-0 with best quality

Cas:52490-15-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

2-Butyl-3-(4-hydroxybenzoyl)benzofuran CAS 52490-15-0

Cas:52490-15-0

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methanone,(2-butyl-3-benzofuranyl)(4-hydroxyphenyl)- 52490-15-0

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2-Butyl-3-(4-hydroxybenzoyl)benzofuran 99%

Cas:52490-15-0

Min.Order:1 Metric Ton

FOB Price: $165.0 / 189.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

2-Butyl-3-(4-hydroxybenzoyl)benzofuran CAS:52490-15-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high q

2-Butyl-3-(4-hydroxybenzoyl)benzofuran CAS:52490-15-0

Cas:52490-15-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Methanone,(2-butyl-3-benzofuranyl)(4-hydroxyphenyl)-

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Methanone,(2-butyl-3-benzofuranyl)(4-hydroxyphenyl)-/ LIDE PHARMA- Factory supply / Best price

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:52490-15-0

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Butyl-3-(4-Hydroxylbenzonyl)Benzofuran

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Manufacturers

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Methanone,(2-butyl-3-benzofuranyl)(4-hydroxyphenyl)- 52490-15-0 CAS NO.52490-15-0

Cas:52490-15-0

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 2-Butyl-3-(4-Hydroxybenzoyl)benzofuran CAS No.: 52490-15-0 Molecule Formula:C19H18O3 Molecule Weight:294.34 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Lower Price 2-Butyl-3-(4-Hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

52490-15-0 CAS NO.52490-15-0

Cas:52490-15-0

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(2-Butylbenzofuran-3-yl)(4-hydroxyphenyl)methanone

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Manufacturers

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediate

2-Butyl-3-(4-hydroxybenzoyl)benzofuran

Cas:52490-15-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Butyl-3-(4-Hydroxy-Benzoyl)-Benzofuran

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Other

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Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity 2-Butyl-3-(4-Hydroxybenzoyl) Benzofuran 52490-15-0

Cas:52490-15-0

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-n-Butyl-3-(4-hydroxybenzoyl)benzo[b]furan

Cas:52490-15-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2-Butyl-3-(4-Hydroxybenzoyl)Benzofuran

Cas:52490-15-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Synthetic route

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran
83790-87-8

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
aluminium chloride In 1,1-dichloroethane; water100%
With aluminum (III) chloride In chlorobenzene at 80℃; for 2h; Inert atmosphere;91.6%
With aluminum (III) chloride In toluene at 80 - 90℃; Solvent; Temperature; Large scale;86.9%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at -20 - -15℃; for 10h; Reflux;92.8%
With aluminum (III) chloride In 1,2-dichloro-ethane at -10 - 60℃; for 7h; Temperature;92%
With aluminum (III) chloride In 1,2-dichloro-ethane at -20 - -10℃; for 10h; Reflux; Large scale;40.1%
Multi-step reaction with 2 steps
1: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
2: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
phosgene
75-44-5

phosgene

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

1,1-dichloroethane
75-34-3

1,1-dichloroethane

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
With sodium hydrogencarbonate; aluminium chloride In water; methoxybenzene70%
4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice
1.2: 75 h / 0 - 20 °C
2.1: sodium thioethylate / N,N-dimethyl-formamide / 16 h / 110 °C
View Scheme
Multi-step reaction with 2 steps
1: aluminum (III) chloride / dichloromethane / 24 h / 20 °C / Inert atmosphere
2: aluminum (III) chloride / chlorobenzene / 2 h / 80 °C / Inert atmosphere
View Scheme
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice
1.2: 75 h / 0 - 20 °C
2.1: sodium thioethylate / N,N-dimethyl-formamide / 16 h / 110 °C
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 5 °C
1.2: 2 h / 5 - 25 °C
2.1: aluminum (III) chloride / toluene / 6 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: aluminum (III) chloride / dichloromethane / 24 h / 20 °C / Inert atmosphere
2: aluminum (III) chloride / chlorobenzene / 2 h / 80 °C / Inert atmosphere
View Scheme
methyl 2-(2-formylphenoxy)hexanoate
138320-26-0

methyl 2-(2-formylphenoxy)hexanoate

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / methanol / 3 h / 20 - 30 °C
1.2: 1 h
2.1: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C
3.1: triethylamine; p-toluenesulfonyl chloride / toluene / 2 h / 70 - 80 °C
3.2: 2 h / 70 - 75 °C
4.1: aluminum (III) chloride / dichloromethane / 10 h / -20 - -15 °C / Reflux
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide / water / 20 - 30 °C / Large scale
2: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
3: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 4 steps
1: sodium hydroxide / water / 20 - 30 °C / Large scale
2: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
3: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
4: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
Multi-step reaction with 4 steps
1: toluene-4-sulfonic acid / methanol / 4 h / 20 - 30 °C / Large scale
2: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C / Large scale
3: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
4: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 5 steps
1: toluene-4-sulfonic acid / methanol / 4 h / 20 - 30 °C / Large scale
2: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C / Large scale
3: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
4: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
5: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
C16H24O5

C16H24O5

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C
2.1: triethylamine; p-toluenesulfonyl chloride / toluene / 2 h / 70 - 80 °C
2.2: 2 h / 70 - 75 °C
3.1: aluminum (III) chloride / dichloromethane / 10 h / -20 - -15 °C / Reflux
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C / Large scale
2: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
3: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 4 steps
1: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C / Large scale
2: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
3: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
4: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
2-(2-formyl-phenoxy)-hexanoic acid
138320-27-1

2-(2-formyl-phenoxy)-hexanoic acid

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine; p-toluenesulfonyl chloride / toluene / 2 h / 70 - 80 °C
1.2: 2 h / 70 - 75 °C
2.1: aluminum (III) chloride / dichloromethane / 10 h / -20 - -15 °C / Reflux
View Scheme
Multi-step reaction with 2 steps
1: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
2: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 3 steps
1: acetic anhydride; sodium acetate / 90 - 100 °C / Large scale
2: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
3: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
methyl 2-bromohexanoate
5445-19-2

methyl 2-bromohexanoate

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide; toluene / 0.5 h / 60 - 70 °C
1.2: 2 h / 80 - 100 °C
2.1: toluene-4-sulfonic acid / methanol / 3 h / 20 - 30 °C
2.2: 1 h
3.1: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C
4.1: triethylamine; p-toluenesulfonyl chloride / toluene / 2 h / 70 - 80 °C
4.2: 2 h / 70 - 75 °C
5.1: aluminum (III) chloride / dichloromethane / 10 h / -20 - -15 °C / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: caesium carbonate; Aliquat 336 / ethyl acetate / 8 h / 80 °C / Large scale
1.2: 5 h / Reflux; Large scale
2.1: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 3 steps
1.1: caesium carbonate; Aliquat 336 / ethyl acetate / 8 h / 80 °C / Large scale
1.2: 5 h / Reflux; Large scale
2.1: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
3.1: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
salicylaldehyde
90-02-8

salicylaldehyde

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide; toluene / 0.5 h / 60 - 70 °C
1.2: 2 h / 80 - 100 °C
2.1: toluene-4-sulfonic acid / methanol / 3 h / 20 - 30 °C
2.2: 1 h
3.1: sodium hydroxide / toluene; water / 4 h / 35 - 40 °C
4.1: triethylamine; p-toluenesulfonyl chloride / toluene / 2 h / 70 - 80 °C
4.2: 2 h / 70 - 75 °C
5.1: aluminum (III) chloride / dichloromethane / 10 h / -20 - -15 °C / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: caesium carbonate; Aliquat 336 / ethyl acetate / 8 h / 80 °C / Large scale
1.2: 5 h / Reflux; Large scale
2.1: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 3 steps
1.1: caesium carbonate; Aliquat 336 / ethyl acetate / 8 h / 80 °C / Large scale
1.2: 5 h / Reflux; Large scale
2.1: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
3.1: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride / toluene / 75 - 85 °C / Large scale
2: aluminum (III) chloride / 1,2-dichloro-ethane / 10 h / -20 - -10 °C / Reflux; Large scale
View Scheme
Multi-step reaction with 3 steps
1: thionyl chloride / toluene / 75 - 85 °C / Large scale
2: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
3: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
1-(4-methoxyphenyl)-1,3-heptanedione
1137261-90-5

1-(4-methoxyphenyl)-1,3-heptanedione

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; aluminum (III) chloride / nitromethane / 6 h / 80 °C
2: boron tribromide / dichloromethane
View Scheme
1-(4-methoxyphenyl)ethanone
100-06-1

1-(4-methoxyphenyl)ethanone

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydride / mineral oil; tetrahydrofuran / Reflux
2: N-Bromosuccinimide; aluminum (III) chloride / nitromethane / 6 h / 80 °C
3: boron tribromide / dichloromethane
View Scheme
methyl valerate
624-24-8

methyl valerate

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydride / mineral oil; tetrahydrofuran / Reflux
2: N-Bromosuccinimide; aluminum (III) chloride / nitromethane / 6 h / 80 °C
3: boron tribromide / dichloromethane
View Scheme
2-Iodophenol
533-58-4

2-Iodophenol

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium carbonate; copper(l) iodide; tetra-(n-butyl)ammonium iodide; palladium / toluene / 40 °C / Inert atmosphere
2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 5 °C
2.2: 2 h / 5 - 25 °C
3.1: aluminum (III) chloride / toluene / 6 h / Reflux
View Scheme
hex-1-yne
693-02-7

hex-1-yne

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium carbonate; copper(l) iodide; tetra-(n-butyl)ammonium iodide; palladium / toluene / 40 °C / Inert atmosphere
2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 5 °C
2.2: 2 h / 5 - 25 °C
3.1: aluminum (III) chloride / toluene / 6 h / Reflux
View Scheme
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran
1951-26-4

2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran

Conditions
ConditionsYield
Stage #1: 2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran With iodine; potassium carbonate In methanol; water at 40 - 65℃;
Stage #2: With hydrogenchloride; sodium sulfite In methanol; water at 20 - 30℃; for 2h; pH=1 - 2; pH-value;
98.8%
With iodine; sodium hydroxide In methanol at 0 - 20℃; for 3h;72%
With iodine; iodic acid In acetic acid
With hydrogenchloride; sodium hydroxide; iodine In methanol0.914 g (47%)
With iodine; potassium carbonate In ethanol for 2h; Reflux;14.61 g
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

(2-butylbenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone

(2-butylbenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone

Conditions
ConditionsYield
With aluminum (III) chloride In chlorobenzene at 80℃; for 2h; Inert atmosphere;91.9%
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

4-(2-butylbenzofuran-3-carbonyl)phenyl sulfurofluoridate

4-(2-butylbenzofuran-3-carbonyl)phenyl sulfurofluoridate

Conditions
ConditionsYield
With potassium fluoride; triethylamine; N,N`-sulfuryldiimidazole; trifluoroacetic acid In dichloromethane at 20℃; for 16h; Sealed tube;91%
With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 18h; Sealed tube;89%
2-chloro-N,N-diethylethylamine hydrochloride
869-24-9

2-chloro-N,N-diethylethylamine hydrochloride

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Dideiodoamiodarone

Dideiodoamiodarone

Conditions
ConditionsYield
With potassium carbonate; sodium iodide In water; toluene at 20℃;88%
benzyl-(2-chloro-ethyl)-ethyl-amine
60154-59-8

benzyl-(2-chloro-ethyl)-ethyl-amine

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

{4-[2-(benzyl-ethyl-amino)-ethoxy]-phenyl}-(2-butyl-benzofuran-3-yl)-methanone
1096359-57-7

{4-[2-(benzyl-ethyl-amino)-ethoxy]-phenyl}-(2-butyl-benzofuran-3-yl)-methanone

Conditions
ConditionsYield
With sodium iodide In N,N-dimethyl-formamide at 20℃; for 24h;85%
pivaloyl chloride
3282-30-2

pivaloyl chloride

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

4-(2-butylbenzofuran-3-carbonyl)phenyl pivalate

4-(2-butylbenzofuran-3-carbonyl)phenyl pivalate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere; Sealed tube;83%
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

ethylene dibromide
106-93-4

ethylene dibromide

2-n-butyl-3-[4-(2-bromo-ethoxy)-benzoyl]-benzofuran

2-n-butyl-3-[4-(2-bromo-ethoxy)-benzoyl]-benzofuran

Conditions
ConditionsYield
With potassium carbonate In chloroform; butanone72.6%
2-(tert-butoxycarbonylamino)ethyl methanesulfonate
96628-67-0

2-(tert-butoxycarbonylamino)ethyl methanesulfonate

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

{2-[4-(2-butyl-benzofuran-3-carbonyl)-phenoxy]-ethyl}-carbamic acid tert-butyl ester
1096359-54-4

{2-[4-(2-butyl-benzofuran-3-carbonyl)-phenoxy]-ethyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20 - 50℃;68%
sodium sulfate
7757-82-6

sodium sulfate

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

ethylene dibromide
106-93-4

ethylene dibromide

2-n-butyl-3-[4-(2-bromo-ethoxy)-benzoyl]-benzofuran

2-n-butyl-3-[4-(2-bromo-ethoxy)-benzoyl]-benzofuran

Conditions
ConditionsYield
With sodium hydroxide; potassium carbonate In diethyl ether; butanone60%
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

(2-butyl-benzofuran-3-yl)-(3,5-dibromo-4-hydroxy-phenyl)-methanone

(2-butyl-benzofuran-3-yl)-(3,5-dibromo-4-hydroxy-phenyl)-methanone

Conditions
ConditionsYield
With N-Bromosuccinimide In dichloromethane; N,N-dimethyl-formamide at -10 - 20℃; for 17h;44%
With bromine In acetic acid-water; acetic acid
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

A

2-n-butyl-3-(3-iodo-4-hydroxybenzoyl)-benzofuran

2-n-butyl-3-(3-iodo-4-hydroxybenzoyl)-benzofuran

B

2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran
1951-26-4

2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran

Conditions
ConditionsYield
With potassium hydroxide; sodium hypochlorite; sodium iodide In methanol at -5℃; for 4h;A 25%
B 11%
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

2-(diethylamino)ethyl chloride
100-35-6

2-(diethylamino)ethyl chloride

Dideiodoamiodarone

Dideiodoamiodarone

Conditions
ConditionsYield
With sodium ethanolate
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

2-n-butyl-3-(3-iodo-4-hydroxybenzoyl)-benzofuran

2-n-butyl-3-(3-iodo-4-hydroxybenzoyl)-benzofuran

Conditions
ConditionsYield
With iodine; iodic acid In acetic acid
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Didesethylamiodarone

Didesethylamiodarone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: I2; HIO3 / acetic acid
2: sodium ethoxide
View Scheme
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Deiodoamiodarone

Deiodoamiodarone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: I2; HIO3 / acetic acid
2: sodium ethoxide
View Scheme
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

(2-butylbenzofuran-3-yl)-[4-ethoxy-3,5-diiodophenyl]-methanone

(2-butylbenzofuran-3-yl)-[4-ethoxy-3,5-diiodophenyl]-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: I2; HIO3 / acetic acid
View Scheme
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

(2-butylbenzofuran-3-yl)-[4-(2-hydroxyethoxy)-3,5-diiodophenyl]-methanone

(2-butylbenzofuran-3-yl)-[4-(2-hydroxyethoxy)-3,5-diiodophenyl]-methanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: I2; HIO3 / acetic acid
View Scheme
phosphoric acid
86119-84-8, 7664-38-2

phosphoric acid

4-chlorosulfonyl-2-hydroxy-benzoic acid
98273-15-5

4-chlorosulfonyl-2-hydroxy-benzoic acid

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

4-[4-(2-Butyl-benzofuran-3-carbonyl)-phenoxysulfonyl]-2-hydroxy-benzoic acid

4-[4-(2-Butyl-benzofuran-3-carbonyl)-phenoxysulfonyl]-2-hydroxy-benzoic acid

Conditions
ConditionsYield
0.185 g (11%)
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

4-[(2-butyl-benzofuran-3-yl)-hydroxy-methyl]-phenol

4-[(2-butyl-benzofuran-3-yl)-hydroxy-methyl]-phenol

Conditions
ConditionsYield
In tetrahydrofuran
tritylaminoethyl chloride

tritylaminoethyl chloride

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

triphenylmethyl alcohol
76-84-6

triphenylmethyl alcohol

Conditions
ConditionsYield
In methanol; water; acetic acid; N,N-dimethyl-formamide
calcium hypochlorite
7778-54-3

calcium hypochlorite

aqueous potassium hypochlorite

aqueous potassium hypochlorite

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

2-n-butyl-3-(3',5'-dichloro-4'-hydroxybenzoyl)benzofuran

2-n-butyl-3-(3',5'-dichloro-4'-hydroxybenzoyl)benzofuran

Conditions
ConditionsYield
With hydrogenchloride; potassium hydroxide; sodium hydroxide; potassium carbonate In methanol; water
2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

A

2-n-butyl-3-[4'-(2,3-epoxy)propoxybenzoyl]benzofuran
55877-12-8

2-n-butyl-3-[4'-(2,3-epoxy)propoxybenzoyl]benzofuran

B

2-n-butyl-3-[4'-(2-hydroxy-3-chloro)propoxybenzoyl]benzofuran

2-n-butyl-3-[4'-(2-hydroxy-3-chloro)propoxybenzoyl]benzofuran

Conditions
ConditionsYield
With sodium hydroxide; sodium chloride In water
1-hydroxy-6-amino-3-naphthalenesulfonic acid
87-02-5

1-hydroxy-6-amino-3-naphthalenesulfonic acid

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

C29H24N2O7S

C29H24N2O7S

Conditions
ConditionsYield
Stage #1: 7-amino-4-hydroxy-2-naphthalenesulfonic acid With hydrogenchloride; sodium nitrite at 0 - 5℃; for 0.5h;
Stage #2: 2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran With sodium hydroxide at 0 - 20℃; for 2.5h; pH=2 - 3;
5-amino-4-hydroxy-naphthalene-1,7-disulfonic acid
6483-81-4

5-amino-4-hydroxy-naphthalene-1,7-disulfonic acid

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

C29H24N2O10S2
1427182-24-8

C29H24N2O10S2

Conditions
ConditionsYield
Stage #1: 5-amino-4-hydroxy-naphthalene-1,7-disulfonic acid With hydrogenchloride; sodium nitrite at 0 - 5℃; for 0.5h;
Stage #2: 2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran With sodium hydroxide at 0 - 20℃; for 2.5h; pH=2 - 3;

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