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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Butylbenzofuran Manufacturer/High quality/Best price/In stock

Cas:4265-27-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Hot selling 2-Butylbenzofuran CAS 4265-27-4 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additi

Hot selling 2-Butylbenzofuran CAS 4265-27-4 with factory price

Cas:4265-27-4

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-butylbenzofuran

Cas:4265-27-4

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 4265-27-4 with best quality

Cas:4265-27-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzofuran, 2-butyl-

Cas:4265-27-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2-Butylbenzofuran CAS:4265-27-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermed

2-Butylbenzofuran CAS:4265-27-4

Cas:4265-27-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzofuran, 2-butyl-

Cas:4265-27-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Benzofuran, 2-butyl-/ LIDE PHARMA- Factory supply / Best price

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzofuran, 2-butyl-

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to make other chemic

Benzofuran, 2-butyl-

Cas:4265-27-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2-BUTYL BENZOFURAN 4265-27-4

Cas:4265-27-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzofuran, 2-butyl-

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Butylbenzofuran

Cas:4265-27-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Johoo Chemical Co., Ltd

High quality products. Always supply highest grade to you. Purity:≥99% Reasonable & Competitive Price. Huge capacity determines the lowest shared cost. The more you buy the more competitive prices you will get. The sincerest and most pro

High quality 2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Metric Ton

FOB Price: $80.5 / 90.5

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationship

TIANFU 4265-27-4 2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2-Butylbenzofuran CAS No.:4265-27-4 Molecule Formula:C12H14O Molecule Weight:174.24 Purity: 99.0% Package: 200kg/drum Description:Light yellow transparent oily liquid Manufacture Standards:Enterprise Standard

Best Quality 2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Butyl-benzofuran

Cas:4265-27-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2-Butylbenzofuran Synonyms: 2-BUTYLBENZOFURAN;2-N-BUTYLBENZO[B]FURAN;2-N-BUTYLBENZOFURAN;2-butyl-benzofura;2-Buthylbenzo【b】furan;2-Butylbenzofurane;2-Butyl;Benzofuran, 2-butyl- CAS: 4265-27-4 MF: C12H14O MW: 174.24 EINECS

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-n-Butylbenzo[b]furan

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-butylbenzofuran

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-n-Butylbenzofuran

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

2-Butylbenzofuran

Cas:4265-27-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol
1248340-86-4

1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
Stage #1: 1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol With butyl magnesium bromide In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 70℃; for 0.166667h;
100%
2-(hex-1-yn-1-yl)phenol
125345-27-9

2-(hex-1-yn-1-yl)phenol

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
Stage #1: 2-(hex-1-yn-1-yl)phenol With N,N,N,N,-tetramethylethylenediamine; diethylzinc In toluene at 120℃; for 1h;
Stage #2: With ammonium chloride In toluene
99%
Stage #1: 2-(hex-1-yn-1-yl)phenol With n-butyllithium In diethyl ether; hexane at 0 - 20℃; for 30h;
Stage #2: With zinc(II) chloride In toluene at 120℃; for 1h;
Stage #3: With ammonium chloride In water; toluene
98%
With caesium carbonate; copper(l) chloride In acetonitrile at 20℃; under 760.051 Torr; for 6h;91.8%
2-Iodophenol
533-58-4

2-Iodophenol

hex-1-yne
693-02-7

hex-1-yne

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With copper(l) iodide; tetra-(n-butyl)ammonium iodide; potassium carbonate; palladium In toluene at 40℃; Reagent/catalyst; Temperature; Sonogashira Cross-Coupling; Inert atmosphere;96.6%
With potassium carbonate at 60℃; for 1h;91%
With copper(l) iodide; L-proline; sodium hydroxide In dimethyl sulfoxide at 80℃; for 12h; Inert atmosphere; Sealed tube;85%
2-phenoxyhexanal
158745-55-2

2-phenoxyhexanal

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With Amberlyst 15 In benzene Heating;94%
With acetic acid; zinc(II) chloride for 0.166667h; Heating;24%
n-butyl magnesium bromide
693-03-8

n-butyl magnesium bromide

2-(methylsulfanyl)benzofuran
36724-16-0

2-(methylsulfanyl)benzofuran

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](triphenylphosphine)nickel(II) dichloride In tetrahydrofuran at 25℃; for 0.5h; Schlenk technique; Inert atmosphere;94%
2-(2-formyl-phenoxy)-hexanoic acid
138320-27-1

2-(2-formyl-phenoxy)-hexanoic acid

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
Stage #1: 2-(2-formyl-phenoxy)-hexanoic acid With triethylamine; p-toluenesulfonyl chloride In toluene at 70 - 80℃; for 2h;
Stage #2: With sodium hydroxide In water; toluene at 70 - 75℃; for 2h;
90%
With sodium acetate; acetic anhydride at 90 - 100℃; Temperature; Reagent/catalyst; Large scale;73.1%
With sodium acetate; acetic anhydride In acetic acid for 8h; Heating;64%
With sodium acetate; acetic anhydride; acetic acid Heating;
1-hexynyl-2-(methoxymethoxy)benzene
125345-26-8

1-hexynyl-2-(methoxymethoxy)benzene

1,3-Dimethoxybenzene
151-10-0

1,3-Dimethoxybenzene

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With gold(III) chloride; silver trifluoromethanesulfonate In dichloromethane at 20℃; for 18h; Inert atmosphere;87%
Hexane-1,2-diol
6920-22-5

Hexane-1,2-diol

phenol
108-95-2

phenol

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With cyclopentene In toluene at 100℃; for 10h; Inert atmosphere; regioselective reaction;85%
1-(2-bromophenyl)-hexan-2-one

1-(2-bromophenyl)-hexan-2-one

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide In N,N-dimethyl-formamide at 105℃; for 22h;82%
1-benzofurane
271-89-6

1-benzofurane

1-bromo-butane
109-65-9

1-bromo-butane

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
Stage #1: 1-benzofurane With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 2h; Inert atmosphere;
Stage #2: 1-bromo-butane In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;
82%
Stage #1: 1-benzofurane With n-butyllithium In tetrahydrofuran at -78℃; for 2h; Schlenk technique; Inert atmosphere;
Stage #2: 1-bromo-butane In tetrahydrofuran at 20℃; for 24h; Schlenk technique; Inert atmosphere;
30%
2-iodophenyl acetate
32865-61-5

2-iodophenyl acetate

hex-1-yne
693-02-7

hex-1-yne

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 70℃; for 20h;81%
(2-Pentanoyloxy-benzyl)-triphenyl-phosphonium; bromide
70339-99-0

(2-Pentanoyloxy-benzyl)-triphenyl-phosphonium; bromide

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With sodium tert-pentoxide In toluene Heating;80%
2-(hex-1-yn-1-yl)phenol
125345-27-9

2-(hex-1-yn-1-yl)phenol

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

(E)-2-(1-(2-n-butyl-benzofuran-3-yl)hex-1-enyl)phenol
1244029-99-9

(E)-2-(1-(2-n-butyl-benzofuran-3-yl)hex-1-enyl)phenol

C

(E)-2-(2-n-butyl-2-(2-n-butylbenzofuran-3-yl)vinyl)phenol
1244029-98-8

(E)-2-(2-n-butyl-2-(2-n-butylbenzofuran-3-yl)vinyl)phenol

Conditions
ConditionsYield
With [Rh(OH)(cod)]2; water; tris(2,6-dimethoxyphenyl)phosphine; lithium chloride In 1,4-dioxane at 90℃; for 24h;A 7%
B 12%
C 80%
1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol
1248340-86-4

1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

3-butylbenzo[b]-furan
36724-27-3

3-butylbenzo[b]-furan

Conditions
ConditionsYield
Stage #1: 1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol With n-butyllithium In tetrahydrofuran at 55℃; for 1h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 70℃; for 0.166667h;
A 22%
B 78%
Stage #1: 1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol With n-butyllithium In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 70℃; for 0.166667h;
A 52%
B 48%
methyl 2-bromohexanoate
5445-19-2

methyl 2-bromohexanoate

salicylaldehyde
90-02-8

salicylaldehyde

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 85 - 90℃; for 8h; Reagent/catalyst; Solvent; Large scale;77.7%
Stage #1: methyl 2-bromohexanoate; salicylaldehyde With Aliquat 336; caesium carbonate In ethyl acetate at 80℃; for 8h; Large scale;
Stage #2: With sodium methylate In toluene for 5h; Reflux; Large scale;
38.6%
C12H14O2

C12H14O2

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With tert-butylisonitrile; palladium diacetate; caesium carbonate In acetonitrile at 20℃; for 15h;76%
carbon dioxide
124-38-9

carbon dioxide

2-(hex-1-yn-1-yl)phenol
125345-27-9

2-(hex-1-yn-1-yl)phenol

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine; cobalt(II) bromide; zinc dibromide; 1,2-bis-(dicyclohexylphosphino)ethane In acetonitrile at 20℃; under 760.051 Torr; for 24h; Schlenk technique; Irradiation;75%
2-(2-chloroacetyl)phenol
53074-73-0

2-(2-chloroacetyl)phenol

butyl magnesium bromide
693-04-9

butyl magnesium bromide

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
Stage #1: 2-(2-chloroacetyl)phenol; butyl magnesium bromide In tetrahydrofuran; toluene at 20 - 55℃; for 1.5h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; toluene
66%
methyl 2-(2-formylphenoxy)hexanoate
138320-26-0

methyl 2-(2-formylphenoxy)hexanoate

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide for 5h; Reagent/catalyst; Solvent; Reflux;65.1%
Multi-step reaction with 2 steps
1: K2CO3 / H2O; methanol / 2 h / Heating
2: Ac2O, AcONa, AcOH / Heating
View Scheme
Multi-step reaction with 2 steps
1: 84 percent / aq. KOH / 2 h / Heating
2: 64 percent / Ac2O, AcONa / acetic acid / 8 h / Heating
View Scheme
2-bromo-1-benzofuran
54008-77-4

2-bromo-1-benzofuran

tri-n-butylbismuthine
3692-81-7

tri-n-butylbismuthine

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In N,N-dimethyl-formamide at 110℃; for 18h; Inert atmosphere;65%
1,2,3-trimethoxybenzene
621-23-8

1,2,3-trimethoxybenzene

1-hexynyl-2-(methoxymethoxy)benzene
125345-26-8

1-hexynyl-2-(methoxymethoxy)benzene

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

3-(2,4,6-trimethoxybenzyl)-2-butylbenzofuran

3-(2,4,6-trimethoxybenzyl)-2-butylbenzofuran

Conditions
ConditionsYield
With gold(III) chloride; silver(I) triflimide In dichloromethane at 20℃; for 18h; Inert atmosphere;A 11%
B 64%
sodium phenoxide
139-02-6

sodium phenoxide

C20H18F6I2O6S2

C20H18F6I2O6S2

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
In methanol for 1h; Ambient temperature;62%
sodium phenoxide
139-02-6

sodium phenoxide

1-(1-hexynyliodonio)-4-phenyliodoniobenzene ditriflate

1-(1-hexynyliodonio)-4-phenyliodoniobenzene ditriflate

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

(4-iodophenyl)(phenyl)iodonium trifluoromethanesulfonate
144930-55-2

(4-iodophenyl)(phenyl)iodonium trifluoromethanesulfonate

Conditions
ConditionsYield
In methanol at 0 - 20℃; for 12h; Cyclization;A 62%
B n/a
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

2-chlorobenzo[b]furan
63361-60-4

2-chlorobenzo[b]furan

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0) In hexane at 40℃; for 24h; Inert atmosphere; Sealed tube;59%
1,2,3-trimethoxybenzene
621-23-8

1,2,3-trimethoxybenzene

1-hexynyl-2-(methoxymethoxy)benzene
125345-26-8

1-hexynyl-2-(methoxymethoxy)benzene

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

2-butyl-3-(methoxymethyl)benzofuran

2-butyl-3-(methoxymethyl)benzofuran

Conditions
ConditionsYield
With platinum(II) chloride; cyclo-octa-1,5-diene In dichloromethane at 30℃; for 22h; Reagent/catalyst; Inert atmosphere;A 11%
B 58%
cyclohexenone
930-68-7

cyclohexenone

2-(hex-1-yn-1-yl)phenol
125345-27-9

2-(hex-1-yn-1-yl)phenol

A

3-(2-butylbenzofuran-3-yl)cyclohexanone

3-(2-butylbenzofuran-3-yl)cyclohexanone

B

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

C

(E)-2-(1-(2-n-butyl-benzofuran-3-yl)hex-1-enyl)phenol
1244029-99-9

(E)-2-(1-(2-n-butyl-benzofuran-3-yl)hex-1-enyl)phenol

D

(E)-2-(2-n-butyl-2-(2-n-butylbenzofuran-3-yl)vinyl)phenol
1244029-98-8

(E)-2-(2-n-butyl-2-(2-n-butylbenzofuran-3-yl)vinyl)phenol

Conditions
ConditionsYield
With tol-BINAP; [Rh(OH)(cod)]2; water; lithium chloride In 1,4-dioxane at 90℃; for 6h;A 9%
B 14%
C 2%
D 47%
2-monochlorophenol
95-57-8

2-monochlorophenol

hex-1-yne
693-02-7

hex-1-yne

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

phenol
108-95-2

phenol

Conditions
ConditionsYield
In water; acetone; acetonitrile for 24h; Sonogashira reaction; Inert atmosphere; Photolysis;A 42%
B 16 %Chromat.
In water; acetone for 24h; Inert atmosphere; Photolysis;A 30 %Chromat.
B 45 %Chromat.
1,2,3-trimethoxybenzene
621-23-8

1,2,3-trimethoxybenzene

1-hexynyl-2-(methoxymethoxy)benzene
125345-26-8

1-hexynyl-2-(methoxymethoxy)benzene

A

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

B

3-(2,4,6-trimethoxybenzyl)-2-butylbenzofuran

3-(2,4,6-trimethoxybenzyl)-2-butylbenzofuran

C

2-butyl-3-(methoxymethyl)benzofuran

2-butyl-3-(methoxymethyl)benzofuran

Conditions
ConditionsYield
With (triphenylphosphine)gold(I) chloride; silver(I) triflimide In dichloromethane at 20℃; for 18h; Inert atmosphere;A 37%
B 27%
C 18%
2-Iodophenol
533-58-4

2-Iodophenol

triethoxy(hex-1-yn-1-yl)silane
218793-76-1

triethoxy(hex-1-yn-1-yl)silane

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With cis-[((2,4,6-trimethylphenylamino)(morpholino)methylidene)]PdCl2(2,4,6-trimethylphenylisonitrile); mercury; sodium hydroxide In 1,4-dioxane; water at 80℃; for 4h; Reagent/catalyst; Hiyama Coupling;24%
1-benzofurane
271-89-6

1-benzofurane

1-iodo-butane
542-69-8

1-iodo-butane

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With n-butyllithium 1) Et2O, 0 deg C, 1 h; Yield given. Multistep reaction;
36%-hydrochloric acid

36%-hydrochloric acid

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran
83790-87-8

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran

Conditions
ConditionsYield
With iron(III) chloride In water; toluene100%
With iron(III) chloride In water; toluene
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

(R)-2-butyl-2,3-dihydrobenzofuran
1372790-92-5

(R)-2-butyl-2,3-dihydrobenzofuran

Conditions
ConditionsYield
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); (x)BF4*C27H27N2(1+); potassium tert-butylate; hydrogen In hexane; toluene at 25℃; under 7500.75 Torr; for 16h; Inert atmosphere; Autoclave; optical yield given as %ee; enantioselective reaction;100%
With hydrogen; C39H36IrNOP(1+)*C32H12BF24(1-) In dichloromethane at 25℃; under 38002.6 Torr; for 24h; Autoclave; Glovebox; enantioselective reaction;93%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran
52490-15-0

2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at -20 - -15℃; for 10h; Reflux;92.8%
With aluminum (III) chloride In 1,2-dichloro-ethane at -10 - 60℃; for 7h; Temperature;92%
With aluminum (III) chloride In 1,2-dichloro-ethane at -20 - -10℃; for 10h; Reflux; Large scale;40.1%
Multi-step reaction with 2 steps
1: aluminum (III) chloride / 1,2-dichloro-ethane / -20 - -10 °C / Large scale
2: aluminum (III) chloride / toluene / 80 - 90 °C / Large scale
View Scheme
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

3,5-diiodo-4-(2-chloroethoxy)benzoyl chloride

3,5-diiodo-4-(2-chloroethoxy)benzoyl chloride

2-butyl-3-[3,5-diiodo-4-(2-chloroethoxy)benzoyl]benzofuran

2-butyl-3-[3,5-diiodo-4-(2-chloroethoxy)benzoyl]benzofuran

Conditions
ConditionsYield
Stage #1: 3,5-diiodo-4-(2-chloroethoxy)benzoyl chloride With aluminum (III) chloride In dichloromethane at -5℃; for 1h;
Stage #2: 2-n-butylbenzo[b]furan In dichloromethane at -5℃; for 13h;
85.4%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran
83790-87-8

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran

Conditions
ConditionsYield
With aluminum (III) chloride In 1,2-dichloro-ethane at -20 - -10℃; Solvent; Temperature; Reagent/catalyst; Large scale;81.2%
With aluminum (III) chloride In dichloromethane at 20℃; for 24h; Inert atmosphere;71%
Stage #1: 2-n-butylbenzo[b]furan With carbon disulfide for 0.5h; Inert atmosphere; Cooling with ice;
Stage #2: 4-methoxy-benzoyl chloride With tin(IV) chloride at 0 - 20℃; for 75h;
64%
Stage #1: 4-methoxy-benzoyl chloride With aluminum (III) chloride In dichloromethane at 0 - 5℃; for 1h;
Stage #2: 2-n-butylbenzo[b]furan In dichloromethane at 5 - 25℃; for 2h;
10.6 g
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

3-bromo-2-n-butylbenzo[b]furan
872400-06-1

3-bromo-2-n-butylbenzo[b]furan

Conditions
ConditionsYield
With N-Bromosuccinimide In tetrahydrofuran at 20℃; for 15h;81%
With N-Bromosuccinimide In chloroform; acetonitrile at -8℃; for 1h;80%
With hydrogen bromide; dimethyl sulfoxide In water; ethyl acetate at 60℃; for 8h;49%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

C11H16O4

C11H16O4

3-(2,4,6-trimethoxybenzyl)-2-butylbenzofuran

3-(2,4,6-trimethoxybenzyl)-2-butylbenzofuran

Conditions
ConditionsYield
With gold(III) chloride; silver trifluoromethanesulfonate In dichloromethane at 20℃; for 18h; Inert atmosphere;79%
phosgene
75-44-5

phosgene

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

1,1-dichloroethane
75-34-3

1,1-dichloroethane

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran
83790-87-8

2-n-butyl 3-(4-methoxy benzoyl)-benzofuran

Conditions
ConditionsYield
With sodium hydrogencarbonate; aluminium chloride In water; methoxybenzene78.7%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

4-(2-butylbenzofuran-3-yl)benzaldehyde
1227008-77-6

4-(2-butylbenzofuran-3-yl)benzaldehyde

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;78%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

2-butyl-2,3-dihydrobenzofuran
109209-69-0

2-butyl-2,3-dihydrobenzofuran

Conditions
ConditionsYield
With ruthenium; hydrogen; 1-butyl-3-methylimidazolium Tetrafluoroborate at 80℃; under 22502.3 Torr; for 48h; Autoclave; chemoselective reaction;75%
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); potassium tert-butylate; hydrogen; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride In hexane at 60℃; under 48754.9 Torr; for 18h; Autoclave;
With hydrogen In neat (no solvent) at 80℃; under 7500.75 Torr; for 24h; Autoclave; chemoselective reaction;
With hydrogen In decalin at 180℃; under 37503.8 Torr; for 16h; Autoclave;
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

1-Bromonaphthalene
90-11-9

1-Bromonaphthalene

2-butyl-3-(1-naphthyl)benzofuran
1227008-84-5

2-butyl-3-(1-naphthyl)benzofuran

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;74%
Nitroethane
79-24-3

Nitroethane

2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

(E)-2-butyl-3-(2-nitrovinyl)benzofuran
1428338-31-1

(E)-2-butyl-3-(2-nitrovinyl)benzofuran

Conditions
ConditionsYield
With palladium(II) trifluoroacetate; silver(I) acetate In 1,2-dimethoxyethane; dimethyl sulfoxide at 100℃; for 24h; Glovebox; Schlenk technique; Inert atmosphere; regioselective reaction;73%
2-n-butylbenzo[b]furan
4265-27-4

2-n-butylbenzo[b]furan

1-(3-Bromophenyl)ethanone
2142-63-4

1-(3-Bromophenyl)ethanone

1-[3-(2-butylbenzofuran-3-yl)phenyl]ethanone
1227008-83-4

1-[3-(2-butylbenzofuran-3-yl)phenyl]ethanone

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;72%

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