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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide Manufacturer/High quality/Best price/In stock

Cas:52509-14-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (1,3-Dioxolan-2-Ylmethyl)Triphenylphosphonium Bromide supplier in China

Cas:52509-14-5

Min.Order:0 Metric Ton

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carb

Methyltriphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

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Wuhan Fortuna Chemical Co.,Ltd

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide CAS 52509-14-5 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide CAS 52509-14-5

Cas:52509-14-5

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (1,3-Dioxolan-2-Ylmethyl)Triphenylphosphonium Bromide

Cas:52509-14-5

Min.Order:1

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EAST CHEMSOURCES LIMITED

Founded in 2008, East Chemsources Limited is a professional manufacturer and supplier in food and chemical field in China. Through more than ten years development, our company has developed from single product at first to provide solution to final

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Metric Ton

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 52509-14-5 (1,3-dioxolan-2-ylmethyl)triphenylphosphonium bromide Manufacturer

Cas:52509-14-5

Min.Order:1 Gram

FOB Price: $0.1

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Chemwill Asia Co., Ltd.

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide -- CHemwill

Cas:52509-14-5

Min.Order:1 Metric Ton

FOB Price: $1.0

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥99% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide CAS52509-14-5

Cas:52509-14-5

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

(1,3-Dioxolan-2-ylmethyl) Triphenylphosphonium Bromide -

Cas:52509-14-5

Min.Order:1 Kilogram

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 52509-14-5 with best quality

Cas:52509-14-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide Synonyms: OMTPPB;LABOTEST-BB LT00233112;(1,3-DIOXOLAN-2-YLMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE;(1,3-DIOXOLANE-2-YL METHYL) TRIPHENYL PHOSPH

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromideCAS NO.:52509-14-5

Cas:52509-14-5

Min.Order:1 Gram

FOB Price: $4.0

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Qingdao Beluga Import and Export Co., LTD

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide CAS: 52509-14-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, special

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide CAS: 52509-14-5

Cas:52509-14-5

Min.Order:1 Gram

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Kilogram

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

(1,3-Dioxolan-2-Ylmethyl)Triphenylphosphonium Bromide

Cas:52509-14-5

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Triumph International Development Limilted

Appearance:white or yellowish white flaky crystal Storage:Keep the sun from direct sunlight ;prevention against high temperature Package:As customer request Application:Used for research and industrial manufacture. Transportatio

(1,3-dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:100 Metric Ton

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Kilogram

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:4 Kilogram

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:100 Gram

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality (1,3-Dioxolan-2-Ylmethyl)Triphenylphosphonium Bromide

Cas:52509-14-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: (1,3-Dioxolan-2-ylmethyl)Triphenylphosphonium Bromide CAS No.:52509-14-5 Molecule Formula:C22H22BrO2P Molecule Weight:429.28 Purity: 98.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise S

High Quality (1,3-Dioxolan-2-ylmethyl)Triphenylphosphonium Bromide in stock

Cas:52509-14-5

Min.Order:1 Kilogram

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide Manufacturer/High quality/Best price/In stock

Cas:52509-14-5

Min.Order:1 Gram

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Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide99%

Cas:52509-14-5

Min.Order:1 Metric Ton

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Shanghai Minstar Chemical Co., Ltd

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide Basic information Product Name: (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide Synonyms: LABOTEST-BB LT00233112;(1,3-DIOXOLAN-2-YLMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE;(1,3-DIOXOLANE-2

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:1 Gram

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Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:0

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Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:0

Negotiable

Type:Manufacturers

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

Cas:52509-14-5

Min.Order:0

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Synthetic route

2-bromomethyl-1,3-dioxolane
4360-63-8

2-bromomethyl-1,3-dioxolane

triphenylphosphine
603-35-0

triphenylphosphine

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

Conditions
ConditionsYield
In isopropyl alcohol at 60 - 65℃; for 3h; Inert atmosphere; Green chemistry;99.1%
In toluene for 24h; Heating / reflux;54%
at 120℃; for 24h;
2-bromomethyl-1,3-dioxolane
4360-63-8

2-bromomethyl-1,3-dioxolane

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

Conditions
ConditionsYield
In toluene for 48h; Reflux;33%
4,15-diformyl[2.2]paracyclophane
288156-11-6

4,15-diformyl[2.2]paracyclophane

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

4,15-bis[(E)-2-formylvinyl]-[2.2]paracyclophane

4,15-bis[(E)-2-formylvinyl]-[2.2]paracyclophane

Conditions
ConditionsYield
Stage #1: 4,15-diformyl[2.2]paracyclophane; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h;
Stage #2: With hydrogenchloride In tetrahydrofuran at 2℃; for 16h;
100%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

4,15-bis[(1E,3E)-4-formylbuta-1,3-dienyl][2.2]paracyclophane

4,15-bis[(1E,3E)-4-formylbuta-1,3-dienyl][2.2]paracyclophane

(2E,4E,6E)-7-[12-((1E,3E,5E)-7-Oxo-hepta-1,3,5-trienyl)-tricyclo[8.2.2.24,7]hexadeca-1(13),4(16),5,7(15),10(14),11-hexaen-5-yl]-hepta-2,4,6-trienal

(2E,4E,6E)-7-[12-((1E,3E,5E)-7-Oxo-hepta-1,3,5-trienyl)-tricyclo[8.2.2.24,7]hexadeca-1(13),4(16),5,7(15),10(14),11-hexaen-5-yl]-hepta-2,4,6-trienal

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide; 4,15-bis[(1E,3E)-4-formylbuta-1,3-dienyl][2.2]paracyclophane With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h;
Stage #2: With hydrogenchloride In tetrahydrofuran at 2℃; for 16h;
100%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

p-(iodophenyl)carboxaldehyde
15164-44-0

p-(iodophenyl)carboxaldehyde

(E)-3-(4-iodophenyl)acrylaldehyde

(E)-3-(4-iodophenyl)acrylaldehyde

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide; p-(iodophenyl)carboxaldehyde With 18-crown-6 ether; sodium hydride In tetrahydrofuran at 25℃; for 14h;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 25℃; for 6h;
100%
With 18-crown-6 ether; sodium hydride In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;78.7%
mesytaldehyde
487-68-3

mesytaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

2-(2,4,6-trimethylstyryl)-1,3-dioxolane

2-(2,4,6-trimethylstyryl)-1,3-dioxolane

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h; Inert atmosphere;
Stage #2: mesytaldehyde In tetrahydrofuran; mineral oil at 20℃; Inert atmosphere;
100%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

5-((allyloxy)methyl)furan-2-carbaldehyde
113675-57-3

5-((allyloxy)methyl)furan-2-carbaldehyde

C11H12O3

C11H12O3

Conditions
ConditionsYield
With sodium methylate In methanol; N,N-dimethyl-formamide at 70℃; for 48h; Wittig Olefination; Inert atmosphere;99%
(E)-3-(methylthio)cinnamaldehyde
1421970-17-3

(E)-3-(methylthio)cinnamaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(2E,4E)-5-(3-(methylthio)phenyl)penta-2,4-dienal
1421970-16-2

(2E,4E)-5-(3-(methylthio)phenyl)penta-2,4-dienal

Conditions
ConditionsYield
Stage #1: (E)-3-(methylthio)cinnamaldehyde; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With sodium methylate In methanol at 25℃; Wittig Olefination; Inert atmosphere;
Stage #2: With iodine In methanol; acetone for 12h; Inert atmosphere; Reflux;
96.2%
C17H26O
860032-97-9

C17H26O

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

C19H28O
1254522-05-8

C19H28O

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: C17H26O In tetrahydrofuran at 20℃; Wittig reaction; Inert atmosphere;
Stage #3: With oxalic acid In tetrahydrofuran; water
96%
quinoline-4-carboxaldehyde
4363-93-3

quinoline-4-carboxaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

4-((E)-2-[1,3]Dioxolan-2-yl-vinyl)-quinoline
172678-77-2

4-((E)-2-[1,3]Dioxolan-2-yl-vinyl)-quinoline

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at -35 - 10℃; for 4h;95%
With lithium methanolate In methanol; N,N-dimethyl-formamide at 70 - 80℃; for 4h;
With potassium tert-butylate In tetrahydrofuran
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

1-benzyl, 2-methyl (2RS,5RS,6RS)-5-ethyl-6-(2-oxoethyl)piperidine-1,2-dicarboxylate

1-benzyl, 2-methyl (2RS,5RS,6RS)-5-ethyl-6-(2-oxoethyl)piperidine-1,2-dicarboxylate

1-benzyl, 2-methyl (2RS,5RS,6RS)-6-[3-(1,3-dioxolan-2-yl)prop-2-enyl]-5-ethylpiperidine-1,2-dicarboxylate

1-benzyl, 2-methyl (2RS,5RS,6RS)-6-[3-(1,3-dioxolan-2-yl)prop-2-enyl]-5-ethylpiperidine-1,2-dicarboxylate

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran Condensation; Wittig reaction;95%
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran for 0.5h;
Stage #2: 1-benzyl, 2-methyl (2RS,5RS,6RS)-5-ethyl-6-(2-oxoethyl)piperidine-1,2-dicarboxylate In tetrahydrofuran Wittig reaction; Further stages.;
95%
C21H30O
1254522-33-2

C21H30O

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

C23H32O
1254522-09-2

C23H32O

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: C21H30O In tetrahydrofuran at 20℃; Wittig reaction; Inert atmosphere;
Stage #3: With oxalic acid In tetrahydrofuran; water
95%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

7-diethylaminocoumarine-3-aldehyde
57597-64-5

7-diethylaminocoumarine-3-aldehyde

(E)-3-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)acrylaldehyde
1403769-30-1

(E)-3-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)acrylaldehyde

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide; 7-diethylaminocoumarine-3-aldehyde In dichloromethane at 20℃; for 0.5h;
Stage #2: With sodium hydroxide In dichloromethane at 20℃; for 3h;
Stage #3: With hydrogenchloride In dichloromethane at 20℃; for 0.2h;
95%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

5-(N,N-dibutylamino)-thiophene-2-carbaldehyde
159874-90-5

5-(N,N-dibutylamino)-thiophene-2-carbaldehyde

(E)-3-(5-(dibutylamino)thiophene-2-yl)acrylaldehyde

(E)-3-(5-(dibutylamino)thiophene-2-yl)acrylaldehyde

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran for 0.5h; Wittig Olefination; Cooling with ice;
Stage #2: 5-(N,N-dibutylamino)-thiophene-2-carbaldehyde In tetrahydrofuran at 20℃;
Stage #3: With oxalic acid In tetrahydrofuran; water for 24h;
94%
C19H28O
1254522-05-8

C19H28O

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

C21H30O
1254522-33-2

C21H30O

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: C19H28O In tetrahydrofuran at 20℃; Wittig reaction; Inert atmosphere;
Stage #3: With oxalic acid In tetrahydrofuran; water
93%
(E)-3-(5-(dimethylamino)thiophen-2-yl)acrylaldehyde

(E)-3-(5-(dimethylamino)thiophen-2-yl)acrylaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(2E,4E)-5-(5-(dimethylamino)thiophen-2-yl)penta-2,4-dienal

(2E,4E)-5-(5-(dimethylamino)thiophen-2-yl)penta-2,4-dienal

Conditions
ConditionsYield
With 18-crown-6 ether; sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 12h;92.9%
3-(4-dimethylamino-phenyl)-propenal
20432-35-3, 6203-18-5

3-(4-dimethylamino-phenyl)-propenal

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

s-trans-((2trans-4trans)-5-(4-dimethylaminophenyl)phenyl)penta-2,4-dienal
20432-36-4

s-trans-((2trans-4trans)-5-(4-dimethylaminophenyl)phenyl)penta-2,4-dienal

Conditions
ConditionsYield
Stage #1: 3-(4-dimethylamino-phenyl)-propenal; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With 18-crown-6 ether; sodium hydride In tetrahydrofuran at 20℃; Wittig reaction;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20℃; for 2h;
92%
With 18-crown-6 ether; sodium hydride In tetrahydrofuran at 20℃; for 12h;58.6%
Stage #1: 3-(4-dimethylamino-phenyl)-propenal; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With 18-crown-6 ether; sodium hydride In tetrahydrofuran at 20℃; for 2h; Wittig Rearrangement; Cooling with ice;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 0.5h;
Stage #3: With potassium carbonate In tetrahydrofuran; water at 20℃;
55%
Stage #1: 3-(4-dimethylamino-phenyl)-propenal; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With 18-crown-6 ether; sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 12h; Wittig Olefination;
Stage #2: With hydrogenchloride at 20℃; for 0.5h;
39%
Stage #1: 3-(4-dimethylamino-phenyl)-propenal; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With 18-crown-6 ether; sodium hydride In tetrahydrofuran
Stage #2: With hydrogenchloride In tetrahydrofuran
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

4,15-bis[(E)-2-formylvinyl]-[2.2]paracyclophane

4,15-bis[(E)-2-formylvinyl]-[2.2]paracyclophane

4,15-bis[(1E,3E)-4-formylbuta-1,3-dienyl][2.2]paracyclophane

4,15-bis[(1E,3E)-4-formylbuta-1,3-dienyl][2.2]paracyclophane

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide; 4,15-bis[(E)-2-formylvinyl]-[2.2]paracyclophane With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h;
Stage #2: With hydrogenchloride In tetrahydrofuran at 2℃; for 16h;
92%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(2-[(N-benzylprolyl)amino]benzophenone)
95019-19-5

(2-[(N-benzylprolyl)amino]benzophenone)

(2E,8E,10E)-dodeca-2,8,10-trienal
864818-23-5

(2E,8E,10E)-dodeca-2,8,10-trienal

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate at 0℃;
Stage #2: (2-[(N-benzylprolyl)amino]benzophenone) for 1h;
Stage #3: With oxalic acid at 20℃; Further stages.;
91%
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: (2-[(N-benzylprolyl)amino]benzophenone) In tetrahydrofuran at 0℃; for 3h;
64%
(1S,2R)-1-(3,4-dichlorophenyl)-2-formyl-cyclopropanecarboxylic acid (4-fluorobenzyl)methylamide
846060-69-3

(1S,2R)-1-(3,4-dichlorophenyl)-2-formyl-cyclopropanecarboxylic acid (4-fluorobenzyl)methylamide

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

sodium cyanoborohydride
25895-60-7

sodium cyanoborohydride

Conditions
ConditionsYield
With potassium hexamethylsilazane In tetrahydrofuran at 20℃; for 2h;91%
C15H24O
1242261-02-4

C15H24O

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

C17H26O
860032-97-9

C17H26O

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: C15H24O In tetrahydrofuran at 20℃; Wittig reaction; Inert atmosphere;
Stage #3: With oxalic acid In tetrahydrofuran; water
91%
2-methylthiobenzaldehyde

2-methylthiobenzaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(E)-2-methylthiocinnamaldehyde
1356939-86-0

(E)-2-methylthiocinnamaldehyde

Conditions
ConditionsYield
Stage #1: 2-methylthiobenzaldehyde; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With sodium hydride; 18-crown-6 ether In tetrahydrofuran at 20℃;
Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0℃;
90.4%
6-Methyl-hept-5-en-2-on
110-93-0

6-Methyl-hept-5-en-2-on

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(E/Z)-3,7-dimethyl-2,6-octadienal
5392-40-5

(E/Z)-3,7-dimethyl-2,6-octadienal

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol at 10 - 20℃; for 4h; Inert atmosphere; Green chemistry;90.1%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

1-benzyl, 2-methyl (2RS,5RS,6RS)-5-[(tert-butyldimethylsilyl)oxy]-6-(2-oxoethyl)piperidine-1,2-dicarboxylate

1-benzyl, 2-methyl (2RS,5RS,6RS)-5-[(tert-butyldimethylsilyl)oxy]-6-(2-oxoethyl)piperidine-1,2-dicarboxylate

1-benzyl, 2-methyl (2RS,5RS,6RS)-5-[(tert-butyldimethylsilyl)oxy]-6-[3-(1,3-dioxolan-2-yl)prop-2-enyl]piperidine-1,2-dicarboxylate

1-benzyl, 2-methyl (2RS,5RS,6RS)-5-[(tert-butyldimethylsilyl)oxy]-6-[3-(1,3-dioxolan-2-yl)prop-2-enyl]piperidine-1,2-dicarboxylate

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran for 0.5h;
Stage #2: 1-benzyl, 2-methyl (2RS,5RS,6RS)-5-[(tert-butyldimethylsilyl)oxy]-6-(2-oxoethyl)piperidine-1,2-dicarboxylate In tetrahydrofuran Wittig reaction; Further stages.;
90%
(1RS,2RS,3RS,4RS,6SR)-6-hydroxy-3,4,6-trimethyl-5,8-dioxobicyclo[2.2.2]octane-2-carbaldehyde

(1RS,2RS,3RS,4RS,6SR)-6-hydroxy-3,4,6-trimethyl-5,8-dioxobicyclo[2.2.2]octane-2-carbaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(1RS,3SR,4RS,7RS,8SR)-8-[2-(1,3-dioxolan-2-yl)-vinyl]-3-hydroxy-1,3,7-trimethylbicyclo[2.2.2]octane-2,6-dione

(1RS,3SR,4RS,7RS,8SR)-8-[2-(1,3-dioxolan-2-yl)-vinyl]-3-hydroxy-1,3,7-trimethylbicyclo[2.2.2]octane-2,6-dione

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: (1RS,2RS,3RS,4RS,6SR)-6-hydroxy-3,4,6-trimethyl-5,8-dioxobicyclo[2.2.2]octane-2-carbaldehyde In tetrahydrofuran at 20℃; for 0.333333h; Wittig reaction; Further stages.;
90%
C23H32O
1254522-09-2

C23H32O

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

C25H34O
1254522-11-6

C25H34O

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: C23H32O In tetrahydrofuran at 20℃; Wittig reaction; Inert atmosphere;
Stage #3: With oxalic acid In tetrahydrofuran; water
90%
trans-4-(4-pentylcyclohexyl)-cyclohexane carboxaldehyde

trans-4-(4-pentylcyclohexyl)-cyclohexane carboxaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

C22H38O2

C22H38O2

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at -30℃; for 1h;
Stage #2: trans-4-(4-pentylcyclohexyl)-cyclohexane carboxaldehyde In tetrahydrofuran at 20℃; for 5h;
90%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carbaldehyde
564-94-3

6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carbaldehyde

(E)-3-(6,6-dimethyl-bicyclo[3.1.1]hept-2-en-2-yl)prop-2-enal
124931-24-4

(E)-3-(6,6-dimethyl-bicyclo[3.1.1]hept-2-en-2-yl)prop-2-enal

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.5h; Sealed tube; Inert atmosphere;
Stage #2: 6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carbaldehyde In tetrahydrofuran at 20℃; for 6h; Sealed tube; Inert atmosphere;
90%
pyridine-4-carbaldehyde
872-85-5

pyridine-4-carbaldehyde

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(E)-3-(pyridin-4-yl)acrylaldehyde
32986-66-6

(E)-3-(pyridin-4-yl)acrylaldehyde

Conditions
ConditionsYield
Stage #1: pyridine-4-carbaldehyde; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With 18-crown-6 ether; sodium hydride In tetrahydrofuran at 20℃; Wittig reaction;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20℃; for 2h;
89%
(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

4-(1H-pyrazol-1-yl)benzaldehyde
99662-34-7

4-(1H-pyrazol-1-yl)benzaldehyde

(2E)-3-[4-(1H-Pyrazol-1-yl)phenyl]-2-propenal
545424-10-0

(2E)-3-[4-(1H-Pyrazol-1-yl)phenyl]-2-propenal

Conditions
ConditionsYield
Stage #1: (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide; 4-(1H-pyrazol-1-yl)benzaldehyde With potassium carbonate; Tris(3,6-dioxaheptyl)amine In dichloromethane; water for 20h; Heating / reflux;
Stage #2: With water; hydrogenchloride In tetrahydrofuran at 20℃; for 1h;
Stage #3: With sodium hydroxide In tetrahydrofuran; water at 0℃;
89%
3-formyl-10-methylphenothiazine
4997-36-8

3-formyl-10-methylphenothiazine

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide
52509-14-5

(1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide

(E)-3-(10-methyl-10H-phenothiazin-3-yl)acrylaldehyde
1374005-27-2

(E)-3-(10-methyl-10H-phenothiazin-3-yl)acrylaldehyde

Conditions
ConditionsYield
With Tris(3,6-dioxaheptyl)amine; potassium carbonate In dichloromethane for 20h; Reflux;88.6%
Stage #1: 3-formyl-10-methylphenothiazine; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With Tris(3,6-dioxaheptyl)amine; potassium carbonate In dichloromethane for 0.2h; Reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 0 - 20℃; for 1h;
80%
Stage #1: 3-formyl-10-methylphenothiazine; (1,3-dioxolan-2-yl-methyl)triphenylphosphonium bromide With Tris(3,6-dioxaheptyl)amine; potassium carbonate In dichloromethane for 24h; Reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 20℃; for 2h;
65%

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