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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-Hexynoic acid Manufacturer/High quality/Best price/In stock

Cas:53293-00-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5-Hexynoic Acid

Cas:53293-00-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Hexynoic acid

Cas:53293-00-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-HEXYNOIC ACID

Cas:53293-00-8

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 53293-00-8 with best quality

Cas:53293-00-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 5-Hexynoic Acid Synonyms: HEX-5-YNOIC ACID;5-HEXYNOIC ACID;TIMTEC-BB SBB009090;RARECHEM AL BO 1092;5-Hexynoicacid,97%;5-HEXYNOIC ACID 98% CAS: 53293-00-8 MF: C6H8O2 MW: 112.13

5-Hexynoic Acid

Cas:53293-00-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Hexynoic acid 53293-00-8

Cas:53293-00-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail bes

99.5% 5-HEXYNOIC ACID CAS:53293-00-8

Cas:53293-00-8

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:53293-00-8

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

5-Hexynoic acid

Cas:53293-00-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

5-HEXYNOIC ACID

Cas:53293-00-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

5-Hexynoic acid

Cas:53293-00-8

Min.Order:1 Kilogram

FOB Price: $300.0 / 400.0

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

5-Hexynoic Acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

5-Hexynoic Acid

Cas:53293-00-8

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 5-Hexynoic acid 100g

Cas:53293-00-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-Hexynoic Acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product name:5-HEXYNOIC ACID Synonyms:4-Ethynylbutyric acid;HEX-5-YNOIC ACID CAS No:53293-00-8 Molecular formula:C6H8O2 Molecular Weight:112.13 Appearance:Yellow Liquid Melting point 27°C (estimate) Boiling point 224-225 °C(lit.)

5-HEXYNOIC ACID china manufacture

Cas:53293-00-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

5-hexynoic acid GMP

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

5-Hexynoic acid cas 53293-00-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

5-Hexynoic acid cas 53293-00-8

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-Hexynoic acid

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

53293-00-8

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zhengzhou Yuanli Biological Technology Co., Ltd.

Top quality with best price, factory supply directlyAppearance:Colorless liquid Storage:Store in a dry, sealed, and dark place Application:Intermediate, organic chemicals

5-HEXYNOIC ACID

Cas:53293-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With jones' reagent In acetone for 1h; Ambient temperature;82%
With chromium(VI) oxide; hydrogen cation In acetone80%
With jones reagent at 0℃;76%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

water
7732-18-5

water

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
In hexane; sulfuric acid; acetone72%
5-hexynonitrile
14918-21-9

5-hexynonitrile

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With sodium hydroxide In water for 10h; Heating;70%
With potassium hydroxide
With potassium hydroxide In methanol; water Heating;
With potassium hydroxide In ethanol; water for 4h; Heating; Yield given;
5,6-dibromohexanoic acid
279214-91-4

5,6-dibromohexanoic acid

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With sodium amide In diethyl ether at -33 - 25℃; Dehydrobromination;70%
With sodium amide In diethyl ether; ammonia at -33℃; for 1.5h;65%
hex-5-ynoic acid tert-butyl ester
73448-14-3

hex-5-ynoic acid tert-butyl ester

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 70℃; for 20h;65%
5,6-dibromohexanoic acid
279214-91-4

5,6-dibromohexanoic acid

A

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

B

6-bromohex-5(E)-enoic acid

6-bromohex-5(E)-enoic acid

Conditions
ConditionsYield
With sodium hydroxide; PEG-2000 at 80℃; for 8h; Dehydrobromination;A 49%
B 19.6%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

A

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

B

hex-5-ynoic acid hex-5-ynyl ester

hex-5-ynoic acid hex-5-ynyl ester

Conditions
ConditionsYield
With chromium(VI) oxide; sulfuric acid; acetone
5-hexynoic acid ethyl ester
108545-38-6

5-hexynoic acid ethyl ester

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With potassium hydroxide
methanol
67-56-1

methanol

2-carbonyl-3-butenenitrile
60556-87-8

2-carbonyl-3-butenenitrile

allenyltrimethylsilane
14657-22-8

allenyltrimethylsilane

A

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

B

6-(trimethylsilyl)hex-5-ynoic acid:
101224-43-5

6-(trimethylsilyl)hex-5-ynoic acid:

Conditions
ConditionsYield
Yield given. Multistep reaction. Yields of byproduct given;
methyl hex-5-ynoate
77758-51-1

methyl hex-5-ynoate

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With potassium hydroxide for 0.5h; Heating;
With water; potassium hydroxide In methanol at 20℃; for 0.5h; Inert atmosphere;
bromobutyric acid
2623-87-2

bromobutyric acid

lithium acetylide
70277-75-7

lithium acetylide

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With ammonia
5,6-dibromohexanoic acid
279214-91-4

5,6-dibromohexanoic acid

A

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

B

6ξ-bromo-hex-5-enoic acid

6ξ-bromo-hex-5-enoic acid

Conditions
ConditionsYield
With potassium hydroxide
5,6-dibromohexanoic acid
279214-91-4

5,6-dibromohexanoic acid

ethanolic KOH-solution

ethanolic KOH-solution

A

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

B

6ξ-bromo-hex-5-enoic acid

6ξ-bromo-hex-5-enoic acid

5,6-dibromohexanoic acid
279214-91-4

5,6-dibromohexanoic acid

A

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

B

hex-4-ynoic acid
41143-12-8

hex-4-ynoic acid

C

6-bromohex-5(E)-enoic acid

6-bromohex-5(E)-enoic acid

Conditions
ConditionsYield
With sodium hydroxide; PEG-2000 In water at 82℃; for 8h;
bromobutyric acid
2623-87-2

bromobutyric acid

lithium acetylide-ethylenediamine complex
1216963-74-4

lithium acetylide-ethylenediamine complex

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
In dimethyl sulfoxide
5-hexenoic acid
1577-22-6

5-hexenoic acid

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Br2 / CH2Cl2 / 1.5 h / -40 °C
2: 65 percent / NaNH2 / diethyl ether; liquid ammonia / 1.5 h / -33 °C
View Scheme
Multi-step reaction with 2 steps
1: Br2 / CH2Cl2 / 1.5 h / -40 °C
2: NaOH; PEG-2000 / H2O / 8 h / 82 °C
View Scheme
Multi-step reaction with 2 steps
1: petroleum ether; bromine
2: ethanolic KOH-solution
View Scheme
5-hexenoic acid
1577-22-6

5-hexenoic acid

Merrifield resin

Merrifield resin

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93.5 percent / Br2 / CH2Cl2 / 1.5 h / -40 °C
2: 70 percent / NaNH2 / diethyl ether / -33 - 25 °C
View Scheme
Multi-step reaction with 2 steps
1: 93.5 percent / Br2 / CH2Cl2 / 1.5 h / -40 °C
2: 49 percent / 40 percent aq. NaOH; PEG-2000 / 8 h / 80 °C
View Scheme
hex-2-yn-1-ol
764-60-3

hex-2-yn-1-ol

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaNH2 / various solvent(s)
2: Jones reagent
View Scheme
methyl 5-hexenoate
2396-80-7

methyl 5-hexenoate

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: aq. KOH / 0.5 h / Heating
View Scheme
6-(2-Nitro-phenylselanyl)-hexanoic acid methyl ester
108545-33-1

6-(2-Nitro-phenylselanyl)-hexanoic acid methyl ester

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 68 percent / aq. H2O2 / tetrahydrofuran / 24 h
3: aq. KOH / 0.5 h / Heating
View Scheme
2-(chloromethyl)tetrahydropyran
18420-41-2, 130233-13-5, 130233-14-6

2-(chloromethyl)tetrahydropyran

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaNH2, liq. NH3 / tetrahydrofuran / -78 °C
2: Jones' reagent / acetone / 0 °C
View Scheme
Tetrahydropyran-2-methanol
100-72-1

Tetrahydropyran-2-methanol

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: SOCl2, pyridine / 10 h / Ambient temperature
2: NaNH2, liq. NH3 / tetrahydrofuran / -78 °C
3: Jones' reagent / acetone / 0 °C
View Scheme
pent-1-yn-5-ol
5390-04-5

pent-1-yn-5-ol

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / 0.17 h / -10 °C
2: NaCN / dimethylsulfoxide / 0.5 h / 70 °C
3: KOH / ethanol; H2O / 4 h / Heating
View Scheme
4-pentynyl-1-tosylate
77758-50-0

4-pentynyl-1-tosylate

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaCN / dimethylsulfoxide / 0.5 h / 70 °C
2: KOH / ethanol; H2O / 4 h / Heating
View Scheme
1-chloro-4-pentyne
14267-92-6

1-chloro-4-pentyne

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 53 percent
2: 70 percent / NaOH / H2O / 10 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: acetone; sodium iodide
2: aqueous acetone
3: aqueous KOH-solution
View Scheme
With hydrogenchloride; potassium hydroxide In water; dimethyl sulfoxide
5-iodopent-1-yne
2468-55-5

5-iodopent-1-yne

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous acetone
2: aqueous KOH-solution
View Scheme
2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol
5244-34-8

2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

Conditions
ConditionsYield
With n-butyllithium In hexane
aqueous potassium hydroxide

aqueous potassium hydroxide

5-hexynonitrile
14918-21-9

5-hexynonitrile

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

methanol
67-56-1

methanol

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

methyl hex-5-ynoate
77758-51-1

methyl hex-5-ynoate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane for 36h; Reflux;100%
With toluene-4-sulfonic acid In dichloromethane for 24h; Esterification; Heating;97%
With toluene-4-sulfonic acid In dichloromethane for 24h; Heating;96%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

hex-5-in-carboxyl chloride
55183-45-4

hex-5-in-carboxyl chloride

Conditions
ConditionsYield
With oxalyl dichloride Inert atmosphere;100%
With oxalyl dichloride; N,N-dimethyl-formamide In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;83%
With oxalyl dichloride; N,N-dimethyl-formamide In benzene at 25 - 35℃; for 2h;82%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

methyl iodide
74-88-4

methyl iodide

methyl hex-5-ynoate
77758-51-1

methyl hex-5-ynoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide100%
With potassium carbonate In N,N-dimethyl-formamide at 5℃; for 5h; Cooling with ice;70%
With potassium carbonate In N,N-dimethyl-formamide
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

6-(trimethylsilyl)hex-5-ynoic acid:
101224-43-5

6-(trimethylsilyl)hex-5-ynoic acid:

Conditions
ConditionsYield
Stage #1: hex-5-ynoic acid With n-butyllithium In tetrahydrofuran at -78℃; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78 - 0℃; Inert atmosphere;
Stage #3: With hydrogenchloride In tetrahydrofuran; water at 0 - 20℃; Inert atmosphere;
100%
Stage #1: hex-5-ynoic acid With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.75h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;
Stage #3: With water; acetic acid In tetrahydrofuran; hexane for 0.333333h;
76%
Stage #1: hex-5-ynoic acid With n-butyllithium In tetrahydrofuran at -78℃; for 0.25h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78 - 20℃; for 4h; Inert atmosphere;
65%
Stage #1: hex-5-ynoic acid With n-butyllithium In tetrahydrofuran at -78℃; for 0.0833333h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78 - 20℃; for 1h; Inert atmosphere;
Stage #3: With hydrogenchloride In tetrahydrofuran; water
63%
Stage #1: hex-5-ynoic acid With n-butyllithium In tetrahydrofuran; Petroleum ether at -78℃;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran; Petroleum ether at -78 - 0℃;
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

sodium 5-hexynoate
1219440-76-2

sodium 5-hexynoate

Conditions
ConditionsYield
With sodium hydrogencarbonate In water at 20℃; for 0.166667h;100%
With sodium hydroxide In water
morpholine
110-91-8

morpholine

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

1-morpholinohex-5-yn-1-one
1293915-62-4

1-morpholinohex-5-yn-1-one

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;100%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap In dichloromethane at 20℃;100%
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane at 23℃; Inert atmosphere;62%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

N-methoxy-N-methylhex-5-ynamide
217087-88-2

N-methoxy-N-methylhex-5-ynamide

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 25℃; Inert atmosphere;100%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0 - 25℃; for 6h;98%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 43h;94%
With 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 16h;
p-nitrobenzene iodide
636-98-6

p-nitrobenzene iodide

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

6-(4-nitrophenyl)hex-5-ynoic acid
1084898-19-0

6-(4-nitrophenyl)hex-5-ynoic acid

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 50℃; for 2h; Inert atmosphere;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 50℃; for 2h; Inert atmosphere;100%
With dichloro bis(acetonitrile) palladium(II); copper(l) iodide; diisopropylamine; triphenylphosphine at 50℃; for 14h; Inert atmosphere; Schlenk technique;74%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine In acetonitrile at 50℃; for 2h; Sonogashira Cross-Coupling; Inert atmosphere;22%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

2,3,5,6-tetraflourophenol
769-39-1

2,3,5,6-tetraflourophenol

2,3,5,6-tetrafluorophenyl hex-5-ynoate
1462237-48-4

2,3,5,6-tetrafluorophenyl hex-5-ynoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24h; Inert atmosphere; Schlenk technique;100%
With pyridinium p-toluenesulfonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h; Inert atmosphere;
1,3-dihydroxyacetone dimer
62147-49-3

1,3-dihydroxyacetone dimer

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

2-oxopropane-1,3-diyl bis(hex-5-ynoate)

2-oxopropane-1,3-diyl bis(hex-5-ynoate)

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃;100%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

4-Iodophenol
540-38-5

4-Iodophenol

6-(4-hydroxyphenyl)hex-5-ynoic acid

6-(4-hydroxyphenyl)hex-5-ynoic acid

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran at 20℃; for 4.5h; Temperature; Inert atmosphere;100%
1-Boc-2-benzylpiperazine

1-Boc-2-benzylpiperazine

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

C22H30N2O3

C22H30N2O3

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 3h;100%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

6-methylidenetetrahydro-2-pyrone
5636-66-8

6-methylidenetetrahydro-2-pyrone

Conditions
ConditionsYield
With [(1,1′-biphenyl-2-yl)di-tert-butylphosphine]gold(I) trifluoromethanesulfonate; silver trifluoromethanesulfonate In chloroform-d1 at 20℃; for 0.0833333h; Reagent/catalyst;99%
With C42H64P4Pd2S4 at 90℃; for 10h; Inert atmosphere;98%
With potassium carbonate; gold(I) chloride In acetonitrile at 20℃; for 2h;97%
N-(2-hydroxy-1-methylethyl)-3-iodobenzamide
863713-59-1

N-(2-hydroxy-1-methylethyl)-3-iodobenzamide

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

6-[3-(2-hydroxy-1-methylethylcarbamoyl)phenyl]hex-5-ynoic acid
863713-63-7

6-[3-(2-hydroxy-1-methylethylcarbamoyl)phenyl]hex-5-ynoic acid

Conditions
ConditionsYield
With pyrrolidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) at 20 - 60℃; for 3.3h; Sonogashira Coupling;99%
Stage #1: N-(2-hydroxy-1-methylethyl)-3-iodobenzamide; hex-5-ynoic acid With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) at 60℃; for 3h; Sonogashira coupling;
Stage #2: N-(2-hydroxy-1-methylethyl)-3-iodobenzamide; hex-5-ynoic acid In water; acetonitrile for 0.333333h; Further stages.;
97%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

(-)-englerin B

(-)-englerin B

C30H38O5

C30H38O5

Conditions
ConditionsYield
With dmap; 2,4,6-trichlorobenzoyl chloride; triethylamine In toluene at 20℃; Yamaguchi esterification; Inert atmosphere;99%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

cholesterol
57-88-5

cholesterol

(3β)-cholest-4-en-3yl hex-5-ynoate
949584-04-7

(3β)-cholest-4-en-3yl hex-5-ynoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 23℃; for 20h;99%
With dmap; dicyclohexyl-carbodiimide59%
2-(2'-hydroxyethylamino)-4,6-di(4'-methoxybenzylamino)-1,3,5-triazine

2-(2'-hydroxyethylamino)-4,6-di(4'-methoxybenzylamino)-1,3,5-triazine

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

2-[2'-(5-hexynoyloxy)ethylamino]-4,6-di(4'-methoxybenzylamino)-1,3,5-triazine
1391054-29-7

2-[2'-(5-hexynoyloxy)ethylamino]-4,6-di(4'-methoxybenzylamino)-1,3,5-triazine

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;99%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

methyl hex-5-ynoate
77758-51-1

methyl hex-5-ynoate

Conditions
ConditionsYield
With chloro-trimethyl-silane In methanol at 20℃; for 16h;99%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

dodeca-5,7-diynedioic acid
28393-04-6

dodeca-5,7-diynedioic acid

Conditions
ConditionsYield
With oxygen; ammonium chloride; copper(l) chloride In water at 20℃;98%
Stage #1: hex-5-ynoic acid With acetyl chloride In methanol at 20 - 80℃; for 12h; Inert atmosphere; Schlenk technique;
Stage #2: With copper(II) acetate monohydrate In acetonitrile at 80℃; for 4h; Reflux; Further stages;
69%
With ammonium chloride; water; copper(l) chloride Reagens 4: Luft;
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

3,4-dihydro-6-methyl-2H-pyran-2-one
3740-59-8

3,4-dihydro-6-methyl-2H-pyran-2-one

Conditions
ConditionsYield
With triphenylphosphine gold (I) chloride; silver trifluoromethanesulfonate In dichloromethane at 20℃; for 16h; Inert atmosphere;98%
With zinc(II) carbonate
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

6-bromo-5-hexynoic acid
910028-80-7

6-bromo-5-hexynoic acid

Conditions
ConditionsYield
With N-Bromosuccinimide; silver nitrate In acetone for 2h;98%
With N-Bromosuccinimide; silver nitrate In acetone at 20℃; for 2h;96%
With N-Bromosuccinimide; silver nitrate In acetone at 20℃; for 2h;72%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

2,3,4,5,6-pentafluorophenol
771-61-9

2,3,4,5,6-pentafluorophenol

pentafluorophenyl 5-hexynoate
1219141-93-1

pentafluorophenyl 5-hexynoate

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In dichloromethane at 0℃;98%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 1h;95%
With dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

C31H35NO7

C31H35NO7

C37H41NO8

C37H41NO8

Conditions
ConditionsYield
With dmap; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine In dichloromethane Inert atmosphere;98%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

5-ketohexanoic acid
3128-06-1

5-ketohexanoic acid

Conditions
ConditionsYield
In water at 90℃; for 45h;98%
With [RhCl2(p-cymene)]2; water at 20℃; for 12h;86%
With platinum catalyst In water at 37℃; for 30h;64%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

methanandamide
157182-49-5

methanandamide

(+)-{(2R)-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoylamino]propyl} 5-hexynoate
1313514-82-7

(+)-{(2R)-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoylamino]propyl} 5-hexynoate

Conditions
ConditionsYield
Stage #1: hex-5-ynoic acid With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: methanandamide In dichloromethane at 20℃; for 10h; Inert atmosphere;
98%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

(S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol
22323-82-6

(S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol

(2'R)-2,3-O-isopropylidene-2,3-dihydroxy-1-prop-1-yl pent-4-ynoate
1341126-40-6

(2'R)-2,3-O-isopropylidene-2,3-dihydroxy-1-prop-1-yl pent-4-ynoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 25℃; for 12h; Inert atmosphere;98%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

(2-(4-(tert-butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazol-1-yl)(piperazin-1-yl)methanone

(2-(4-(tert-butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazol-1-yl)(piperazin-1-yl)methanone

1-(4-(2-(4-(tert-butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-1-yl)hex-5-yn-1-one

1-(4-(2-(4-(tert-butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-1-yl)hex-5-yn-1-one

Conditions
ConditionsYield
Stage #1: hex-5-ynoic acid With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;
Stage #2: (2-(4-(tert-butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazol-1-yl)(piperazin-1-yl)methanone In N,N-dimethyl-formamide at 20℃; for 3h;
98%
formaldehyd
50-00-0

formaldehyd

hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

1-((S)-3-azido-2-isocyanopropyl)benzene
1223635-87-7

1-((S)-3-azido-2-isocyanopropyl)benzene

(S)-2-[(1-azido-3-phenylpropan-2-yl)amino]-2-oxoethyl hex-5-ynoate

(S)-2-[(1-azido-3-phenylpropan-2-yl)amino]-2-oxoethyl hex-5-ynoate

Conditions
ConditionsYield
In methanol at 20℃; Passerini Condensation;98%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

(E)-5,6-dibromopent-5-enoic acid

(E)-5,6-dibromopent-5-enoic acid

Conditions
ConditionsYield
With bromine; magnesium bromide ethyl etherate; sodium bromide In dichloromethane at 20℃;98%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

(7S)‐2‐(4‐phenoxyphenyl)‐7‐(piperidin‐4‐yl)‐4H,5H,6H,7H‐pyrazolo[1,5‐a]pyrimidine‐3‐carboxamide

(7S)‐2‐(4‐phenoxyphenyl)‐7‐(piperidin‐4‐yl)‐4H,5H,6H,7H‐pyrazolo[1,5‐a]pyrimidine‐3‐carboxamide

(S)-7-(1-(hex-5-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-3-carboxamide

(S)-7-(1-(hex-5-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine-3-carboxamide

Conditions
ConditionsYield
With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;98%

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