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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-hexyn-1-ol

Cas:928-90-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5-Hexyn-1-Ol

Cas:928-90-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

5-HEXYN-1-OL

Cas:928-90-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 928-90-5 with best quality

Cas:928-90-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name 5-Hexyn-1-ol/Hex-5-yn-1-ol CAS NO. 928-90-5 Molecular Formula C6H10O Molecular Weight 98.14 Appearance Colorless Cl

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

5-HEXYN-1-OL CAS:928-90-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

5-HEXYN-1-OL CAS:928-90-5

Cas:928-90-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:928-90-5

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price & quick delivery Appearance:Clear pale yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Hydroxy-5-hexyne

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Hex-5-yn-1-ol CAS No.:928-90-5 Molecule Formula:C6H10O Molecule Weight:98.14 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS SPECIFIC

Best Quality Hex-5-yn-1-ol with good supplier

Cas:928-90-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

color Colorless to pale yellow Specific Gravity 0.880 Water Solubility Slightly miscible with water. BRN 1739774 CAS DataBase Reference 928-90-5(CAS DataBase Reference) Safety Information Hazard Codes Xi Risk Statements 36/

5-HEXYN-1-OL

Cas:928-90-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

5-HEXYN-1-OL

Cas:928-90-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-HEXYN-1-OL cas no. 928-90-5 97%

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 5-Hexyn-1-ol 25g

Cas:928-90-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product name:5-HEXYN-1-OL Synonyms:1-Hydroxy-5-hexyne;5-hexyn-1-0l;6-Hydroxy-1-hexyne;Hex-5-yn-1-ol CAS No:928-90-5 Molecular formula:C6H10O Molecular Weight:98.14 Appearance:Colorless to pale yellow Liquid Melting point - 34 ° C (estimate)

5-HEXYN-1-OL china manufacture

Cas:928-90-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

5-HEXYN-1-OL CAS No.928-90-5

Cas:928-90-5

Min.Order:0

Negotiable

Type:Trading Company

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Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

5-Hexyn-1-ol

Cas:928-90-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

tert-butyldimethylsilyl hex-5-yn-1-yl ether
73448-13-2

tert-butyldimethylsilyl hex-5-yn-1-yl ether

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With hydrogenchloride In methanol; water at 23℃; for 1h; Inert atmosphere;93%
With triethylamine hydrofluoride In tetrahydrofuran at 50℃; for 19h; var. reag.: (n-Bu)4N(1+)*F(1-);86%
2-(hex-5-yn-1-yloxy)tetrahydro-2H-pyran
1720-37-2

2-(hex-5-yn-1-yloxy)tetrahydro-2H-pyran

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With ammonium nitrate; Montmorillonite-K10 for 0.0583333h; deprotection; microwave irradiation;86%
With ethanol; pyridinium p-toluenesulfonate at 55℃; var. reag.: TsOH, MeOH, 25 deg C, 7 h;73%
With pyridinium p-toluenesulfonate In ethanol at 25℃; for 3h;
2-(chloromethyl)tetrahydropyran
18420-41-2, 130233-13-5, 130233-14-6

2-(chloromethyl)tetrahydropyran

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With sodium amide; ferric nitrate In ammonia Whiting's double elimination;85%
With sodium amide In ammonia83%
With Iron(III) nitrate nonahydrate; ammonia; sodium for 4h; Cooling;67%
hex-5-ynoic acid
53293-00-8

hex-5-ynoic acid

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 15h; Inert atmosphere;82%
With LiAlH4 In diethyl ether
1-((hex-5-yn-1-yloxy)methyl)-4-methoxybenzene
123186-35-6

1-((hex-5-yn-1-yloxy)methyl)-4-methoxybenzene

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With trichlorophosphate In 1,2-dichloro-ethane at 20℃; for 0.833333h;80%
With acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite at 20℃; for 18h; Green chemistry; chemoselective reaction;72%
hex-2-yn-1-ol
764-60-3

hex-2-yn-1-ol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With sodium hydride; ethylenediamine In mineral oil at 0 - 70℃;52%
With sodium amide In various solvent(s)
With potassium tert-butylate; lithium; Trimethylenediamine at 20℃; Zipper reaction; Inert atmosphere;
methyl hex-5-ynoate
77758-51-1

methyl hex-5-ynoate

allyl-trimethyl-silane
762-72-1

allyl-trimethyl-silane

A

non-1-en-8-yn-4-ol

non-1-en-8-yn-4-ol

B

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With indium (III) iodide; Dimethylphenylsilane In dichloromethane at 20℃; for 1.66667h; Inert atmosphere; chemoselective reaction;A 40%
B 22 %Spectr.
nitrite d'hexyne-5 ol-1
77566-25-7

nitrite d'hexyne-5 ol-1

A

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

B

5-hexynal
29329-03-1

5-hexynal

C

(hydroxy-3 propyl)-3 isoxazole
77566-35-9

(hydroxy-3 propyl)-3 isoxazole

Conditions
ConditionsYield
In benzene at 10 - 20℃; for 26h; Irradiation;A 17%
B 5%
C 11%
3-hexyn-1-ol
1002-28-4

3-hexyn-1-ol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With propane-1,3-diamine potassium salt
5-hexyn-1-yl acetate
68274-83-9

5-hexyn-1-yl acetate

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With potassium hydroxide In methanol Heating;
hex-5-ynyloxy-trimethyl-silane
17889-21-3

hex-5-ynyloxy-trimethyl-silane

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With sulfuric acid
methyl hex-5-ynoate
77758-51-1

methyl hex-5-ynoate

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

2-(chloromethyl)tetrahydropyran
18420-41-2, 130233-13-5, 130233-14-6

2-(chloromethyl)tetrahydropyran

ammonia
7664-41-7

ammonia

sodium

sodium

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

1-chloro-4-tetrahydropyranyloxybutane
41302-05-0

1-chloro-4-tetrahydropyranyloxybutane

lithium acetylide-ethylenediamine complex

lithium acetylide-ethylenediamine complex

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Yield given. Multistep reaction;
Tetrahydropyran-2-methanol
100-72-1

Tetrahydropyran-2-methanol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Stage #1: Tetrahydropyran-2-methanol With pyridine; thionyl chloride
Stage #2: With ammonia; sodium amide Further stages.;
Multi-step reaction with 2 steps
1: 65 percent / SOCl2 / pyridine / 8 h / 45 °C
2: 85 percent / NaNH2 / Fe(NO3)3*9H2O / liquid ammonia
View Scheme
Multi-step reaction with 2 steps
1: SOCl2 / pyridine
2: Na / liquid ammonia
View Scheme
1-phenylbut-1-en-3-yne
5622-76-4

1-phenylbut-1-en-3-yne

6-bromo-hex-5-yn-1-ol
69284-62-4

6-bromo-hex-5-yn-1-ol

A

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

B

10-phenyldec-9-ene-5,7-diyn-1-ol

10-phenyldec-9-ene-5,7-diyn-1-ol

Conditions
ConditionsYield
With hydroxylamine hydrochloride; isopropylamine; copper(l) chloride In ethanol for 18h; Inert atmosphere;
1-(tert-butyldiphenylsilyloxy)-5-hexyne
128217-23-2

1-(tert-butyldiphenylsilyloxy)-5-hexyne

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); sulfuric acid; water In methanol at 20℃; for 24h; Inert atmosphere;
1-(tert-butyldiphenylsilyloxy)-5-hexyne
128217-23-2

1-(tert-butyldiphenylsilyloxy)-5-hexyne

A

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

B

6-(tert-butyldiphenylsilyloxy)hexan-2-one
123171-29-9

6-(tert-butyldiphenylsilyloxy)hexan-2-one

Conditions
ConditionsYield
With 2-dicyclohexyl(2′,6′-dimethoxybiphenyl)phosphine gold(I)bis(trifluoromethanesulfonyl)imide; water In methanol at 20℃; Inert atmosphere;A 15 %Chromat.
B 85 %Chromat.
5,6-dibromohexan-1-ol
18343-91-4

5,6-dibromohexan-1-ol

A

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

B

5-bromohex-5-en-1-ol
69441-76-5

5-bromohex-5-en-1-ol

Conditions
ConditionsYield
With potassium tert-butylate In tert-butyl alcohol at 40℃; for 24h; Reflux;
5-hydroxypentanal
4221-03-8

5-hydroxypentanal

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate
90965-06-3

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
With potassium carbonate In methanol at 20℃; for 5.5h; Seyferth-Gilbert Homologation;
valeric acid
13392-69-3

valeric acid

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 6 h / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C
3: potassium carbonate / methanol / 5.5 h / 20 °C
View Scheme
5-hydroxy-N,O-dimethyl-pentanohydroxamic acid
187756-41-8

5-hydroxy-N,O-dimethyl-pentanohydroxamic acid

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C
2: potassium carbonate / methanol / 5.5 h / 20 °C
View Scheme
1 ,5-pentanediol
111-29-5

1 ,5-pentanediol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
1.2: 3.17 h / -78 - 23 °C / Inert atmosphere
2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hydrogencarbonate / dichloromethane; water / 0 °C / Inert atmosphere
2.2: 0.25 h / 0 - 23 °C / Inert atmosphere
3.1: triphenylphosphine / dichloromethane / 3.17 h / 0 - 23 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 23 °C / Inert atmosphere
5.1: hydrogenchloride / water; methanol / 1 h / 23 °C / Inert atmosphere
View Scheme
5-(tert-butyldimethyl-silyloxy)pentan-1-ol
83067-20-3

5-(tert-butyldimethyl-silyloxy)pentan-1-ol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hydrogencarbonate / dichloromethane; water / 0 °C / Inert atmosphere
1.2: 0.25 h / 0 - 23 °C / Inert atmosphere
2.1: triphenylphosphine / dichloromethane / 3.17 h / 0 - 23 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 23 °C / Inert atmosphere
4.1: hydrogenchloride / water; methanol / 1 h / 23 °C / Inert atmosphere
View Scheme
5-tert-butyldimethylsilyloxypentanal
87184-80-3

5-tert-butyldimethylsilyloxypentanal

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triphenylphosphine / dichloromethane / 3.17 h / 0 - 23 °C / Inert atmosphere
2: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 23 °C / Inert atmosphere
3: hydrogenchloride / water; methanol / 1 h / 23 °C / Inert atmosphere
View Scheme
1,1-dibromo-6-(tert-butyldimethylsiloxy)hex-1-ene
306734-44-1

1,1-dibromo-6-(tert-butyldimethylsiloxy)hex-1-ene

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 - 23 °C / Inert atmosphere
2: hydrogenchloride / water; methanol / 1 h / 23 °C / Inert atmosphere
View Scheme
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

2-(hex-5-yn-1-yloxy)tetrahydro-2H-pyran
1720-37-2

2-(hex-5-yn-1-yloxy)tetrahydro-2H-pyran

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane at 0℃; for 1.25h;100%
With water; sodium hydrogencarbonate; 8-aminopyrene-1,3,6-trisulfonic acid, trisodium salt98%
toluene-4-sulfonic acid In dichloromethane98%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-trimethylsilanyl-hex-5-yn-1-ol
103437-52-1

6-trimethylsilanyl-hex-5-yn-1-ol

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol With ethylmagnesium bromide
Stage #2: chloro-trimethyl-silane
Stage #3: With sulfuric acid In tetrahydrofuran
100%
Stage #1: 5-hexyl-1-ol With n-butyllithium In tetrahydrofuran at -78℃; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78 - 0℃; Inert atmosphere;
Stage #3: With hydrogenchloride In tetrahydrofuran; water at 0 - 20℃; Inert atmosphere;
100%
Stage #1: 5-hexyl-1-ol With dmap; n-butyllithium In tetrahydrofuran; diethyl ether; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane at -78 - 20℃; for 2h; Inert atmosphere;
99%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-butyldimethylsilyl hex-5-yn-1-yl ether
73448-13-2

tert-butyldimethylsilyl hex-5-yn-1-yl ether

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 20h; Ambient temperature;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 0.333333h; Inert atmosphere;100%
With 1H-imidazole; dmap In dichloromethane at 20℃; for 1h; Inert atmosphere;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

hex-5-ynyl methanesulphonate
79496-61-0

hex-5-ynyl methanesulphonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃;100%
With triethylamine In diethyl ether at 0℃; for 3h;99%
With triethylamine In dichloromethane at 0 - 20℃; for 14h; Inert atmosphere;98%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

trimethylaluminum
75-24-1

trimethylaluminum

5-methylhex-5-en-1-ol
5212-80-6

5-methylhex-5-en-1-ol

Conditions
ConditionsYield
With zirconocene dichloride In hexane; 1,2-dichloro-ethane at 20℃; for 22h; Addition;100%
dibutyl disulfide
629-45-8

dibutyl disulfide

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

(Z)-1,2-bis(butylthio)-1-hexen-6-ol

(Z)-1,2-bis(butylthio)-1-hexen-6-ol

Conditions
ConditionsYield
With rhodium hydrido (PEt3)3 complex; trifluorormethanesulfonic acid; P(p-CH3OC6H4)3 In acetone for 10h; Heating;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

A

(E)-6-iodo-5-hexen-1-ol
201035-80-5

(E)-6-iodo-5-hexen-1-ol

B

(Z)-6-iodo-5-hexene-1-ol
132716-07-5, 106335-91-5

(Z)-6-iodo-5-hexene-1-ol

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In benzene for 3.5h; Heating;
Stage #2: With iodine In dichloromethane at 0℃; for 1.3h; Title compound not separated from byproducts;
A 100%
B n/a
Multi-step reaction with 2 steps
1: 2,2'-azobis(isobutyronitrile) / tetrahydrofuran / 14 h / 80 - 90 °C / Inert atmosphere
2: iodine / dichloromethane / 14 h / 80 - 90 °C / Inert atmosphere
View Scheme
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

benzoyl chloride
98-88-4

benzoyl chloride

6-benzoyloxy-1-hexyne
216064-35-6

6-benzoyloxy-1-hexyne

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 0 - 20℃; for 1h;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃;100%
With triethylamine In dichloromethane at 0 - 20℃;99%
4-(4-bromophenyl)-3-butyn-1-ol
59099-79-5

4-(4-bromophenyl)-3-butyn-1-ol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-(4-(4-hydroxy-1-butynyl)phenyl)-5-hexyn-1-ol
857349-14-5

6-(4-(4-hydroxy-1-butynyl)phenyl)-5-hexyn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In dichloromethane at 50℃; Sonogashira reaction;100%
4-(4-bromophenyl)-4-pentyn-1-ol
857349-11-2

4-(4-bromophenyl)-4-pentyn-1-ol

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-(4-(5-hydroxy-1-pentynyl)phenyl)-5-hexyn-1-ol
857349-13-4

6-(4-(5-hydroxy-1-pentynyl)phenyl)-5-hexyn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In dichloromethane at 50℃; Sonogashira reaction;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

para-iodoanisole
696-62-8

para-iodoanisole

4-(6-hydroxy-hex-1-ynyl)-methoxybenzene
128599-33-7

4-(6-hydroxy-hex-1-ynyl)-methoxybenzene

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol; para-iodoanisole With copper(l) iodide; N-ethyl-N,N-diisopropylamine; triphenylphosphine In tetrahydrofuran for 1h; Sonogashira coupling;
Stage #2: bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran for 12h;
100%
With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine In tetrahydrofuran at 20℃; Sonogashira Cross-Coupling; Inert atmosphere;96%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 2.5h;94%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

4-tolyl iodide
624-31-7

4-tolyl iodide

6-(p-tolyl)hex-5-yn-1-ol

6-(p-tolyl)hex-5-yn-1-ol

Conditions
ConditionsYield
Stage #1: 4-tolyl iodide With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 0.166667h;
Stage #2: 5-hexyl-1-ol at 20℃;
100%
With C24H28Cl2N2PPd; tetrabutyl ammonium fluoride In N,N-dimethyl-formamide at 110℃; for 6h; Sonogashira Cross-Coupling; Inert atmosphere;96%
With potassium phosphate; copper(l) iodide; (E)-1,1-diphenyl-2-(pyridin-2-ylmethylene)hydrazine; dichloro bis(acetonitrile) palladium(II) In N,N-dimethyl-formamide at 70℃; for 5h; Sonogashira cross-coupling;73%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

isobutene
115-11-7

isobutene

tert-butyl 5-hexynyl ether
121587-75-5

tert-butyl 5-hexynyl ether

Conditions
ConditionsYield
With Amberlyst In hexane at 20℃; for 14h; Inert atmosphere;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

1,4-dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate
170011-47-9

1,4-dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate

6-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)hex-5-yn-1-ol

6-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)hex-5-yn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine In tetrahydrofuran at 20℃; Sonogashira Cross-Coupling; Inert atmosphere;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

((3aS,4R,7R,7aS)-7-(3-azidopropyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)methyl ((tert-butoxycarbonyl)leucyl)sulfamate

((3aS,4R,7R,7aS)-7-(3-azidopropyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)methyl ((tert-butoxycarbonyl)leucyl)sulfamate

((3aS,4R,7R,7aS)-7-(3-(4-(4-hydroxybutyl)-1H-1,2,3-triazol-1-yl)propyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)methyl ((tert-butoxycarbonyl)leucyl)sulfamate

((3aS,4R,7R,7aS)-7-(3-(4-(4-hydroxybutyl)-1H-1,2,3-triazol-1-yl)propyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)methyl ((tert-butoxycarbonyl)leucyl)sulfamate

Conditions
ConditionsYield
With copper(l) iodide; triethylamine In N,N-dimethyl-formamide at 50℃; Inert atmosphere;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

1-((hex-5-yn-1-yloxy)methyl)-4-methoxybenzene
123186-35-6

1-((hex-5-yn-1-yloxy)methyl)-4-methoxybenzene

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 18h; Inert atmosphere;100%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-azidohexan-1-ol
146292-90-2

6-azidohexan-1-ol

6-(4-(4-hydroxybutyl)-1H-1,2,3-triazol-1-yl)hexan-1-ol
1240924-00-8

6-(4-(4-hydroxybutyl)-1H-1,2,3-triazol-1-yl)hexan-1-ol

Conditions
ConditionsYield
With polyvinylpyrrolidone coated copper(I) oxide nanoparticles In water at 37℃; for 48h; Sonication;99.8%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

5-hexynyl p-toluenesulfonate
76911-01-8

5-hexynyl p-toluenesulfonate

Conditions
ConditionsYield
With pyridine at 0℃; for 16h;99%
With 1-methyl-1H-imidazole; triethylamine In toluene at 20℃; for 1h; Cooling with ice;99.7%
With pyridine at 0℃; for 6h;98%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-bromo-1-hexyne
66977-99-9

6-bromo-1-hexyne

Conditions
ConditionsYield
With carbon tetrabromide; triphenylphosphine In dichloromethane at 20℃; for 1h; Inert atmosphere;99%
With bromine; triphenylphosphine In acetonitrile at 0℃;87%
With carbon tetrabromide; triphenylphosphine In diethyl ether for 1h; Ambient temperature;65%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

acetic anhydride
108-24-7

acetic anhydride

5-hexyn-1-yl acetate
68274-83-9

5-hexyn-1-yl acetate

Conditions
ConditionsYield
With pyridine at 20℃; for 3h;99%
With pyridine for 3h; Ambient temperature;97%
With dmap; potassium carbonate In ethyl acetate95%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

1-(tert-butyldiphenylsilyloxy)-5-hexyne
128217-23-2

1-(tert-butyldiphenylsilyloxy)-5-hexyne

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol With 1H-imidazole In dichloromethane at 0℃; for 0.166667h;
Stage #2: tert-butylchlorodiphenylsilane In dichloromethane at 0 - 20℃; for 17h;
99%
With 1H-imidazole In tetrahydrofuran at 20℃;96%
With 1H-imidazole In tetrahydrofuran at 20℃; for 2h;96%
iodobenzene
591-50-4

iodobenzene

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-phenylhex-5-yn-1-ol
69936-53-4

6-phenylhex-5-yn-1-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 12h; Inert atmosphere;99%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 18h; Inert atmosphere;99%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); diisopropylamine In tetrahydrofuran at 20℃;98%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

benzyl bromide
100-39-0

benzyl bromide

1-benzyloxy-5-hexyne
60789-55-1

1-benzyloxy-5-hexyne

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; Schlenk technique; Inert atmosphere;99%
Stage #1: 5-hexyl-1-ol With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: benzyl bromide In tetrahydrofuran at 0 - 20℃; for 90h;
99%
With tetra-(n-butyl)ammonium iodide; potassium hydride In tetrahydrofuran at 0 - 25℃; Inert atmosphere;97%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

1-((hex-5-yn-1-yloxy)methyl)-4-methoxybenzene
123186-35-6

1-((hex-5-yn-1-yloxy)methyl)-4-methoxybenzene

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 18h; Inert atmosphere;99%
With sodium hydride In mineral oil99%
Stage #1: 5-hexyl-1-ol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 2h; Inert atmosphere;
Stage #2: p-methoxybenzyl chloride With tetra-(n-butyl)ammonium iodide In tetrahydrofuran; mineral oil at 20℃; for 24h; Inert atmosphere;
91%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

o-nitroiodobenzene
609-73-4

o-nitroiodobenzene

2-(6-hydroxy-1-hexynyl)nitrobenzene
442155-84-2

2-(6-hydroxy-1-hexynyl)nitrobenzene

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Sonogashira coupling;99%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 13h; Sonogashira coupling;99%
Stage #1: 5-hexyl-1-ol; o-nitroiodobenzene With bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine In N,N-dimethyl-formamide for 0.5h; Sonogashira coupling; Inert atmosphere;
Stage #2: With copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 5.16667h; Sonogashira coupling; Inert atmosphere;
71%
p-nitrobenzene iodide
636-98-6

p-nitrobenzene iodide

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

(Z)-6-(4-nitrophenyl)-5-hexen-1-ol

(Z)-6-(4-nitrophenyl)-5-hexen-1-ol

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol With triethyl borane; dichloroindium hydride In tetrahydrofuran; hexane at -78℃; for 2.5h;
Stage #2: p-nitrobenzene iodide With 1,3-dimethyl-2-imidazolidinone; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; trifuran-2-yl-phosphane In tetrahydrofuran; hexane for 0.5h; Heating;
99%
Stage #1: 5-hexyl-1-ol With indium(III) chloride; triethyl borane; diisobutylaluminium hydride In tetrahydrofuran; hexane at -78℃; for 2.5h;
Stage #2: p-nitrobenzene iodide With trifuran-2-yl-phosphane; tris(dibenzylideneacetone)dipalladium(0) chloroform complex In tetrahydrofuran; hexane at 66℃; for 0.5h; Further stages.;
99%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

2-iodochlorobenzene
615-41-8

2-iodochlorobenzene

6-(2-chloro-phenyl)-hex-5-yn-1-ol
608130-99-0

6-(2-chloro-phenyl)-hex-5-yn-1-ol

Conditions
ConditionsYield
With copper(l) iodide; diisopropylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride at 84℃; for 6h; Sonogashira coupling;99%
5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

(Z)-6-(3-methoxyphenyl)-5-hexen-1-ol

(Z)-6-(3-methoxyphenyl)-5-hexen-1-ol

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol With indium(III) chloride; triethyl borane; diisobutylaluminium hydride In tetrahydrofuran; hexane at -40℃; for 2.5h;
Stage #2: 3-methoxy-1-iodobenzene With trifuran-2-yl-phosphane; tris(dibenzylideneacetone)dipalladium(0) chloroform complex In tetrahydrofuran; hexane at 66℃; for 0.5h; Further stages.;
99%
iodobenzene
591-50-4

iodobenzene

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

4-{1-phenyl-[1,2,3]triazol-4-yl}butan-1-ol

4-{1-phenyl-[1,2,3]triazol-4-yl}butan-1-ol

Conditions
ConditionsYield
With sodium azide; trans-N,N'-dimethylcyclohexane-1,2-diamine; sodium L-ascorbate; copper(l) iodide In dimethyl sulfoxide at 20℃; for 1.5h;99%
triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

5-hexyl-1-ol
928-90-5

5-hexyl-1-ol

6-(triisopropyl-silanyl)hex-5-yn-1-ol
290813-10-4

6-(triisopropyl-silanyl)hex-5-yn-1-ol

Conditions
ConditionsYield
Stage #1: 5-hexyl-1-ol With ethylmagnesium bromide In tetrahydrofuran for 8h; Heating;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran for 18h; Heating; Further stages.;
99%
Stage #1: 5-hexyl-1-ol With ethylmagnesium chloride In tetrahydrofuran at 20℃; Inert atmosphere; Reflux;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran for 4h; Inert atmosphere; Reflux;
85%
Stage #1: 5-hexyl-1-ol With ethylmagnesium chloride In tetrahydrofuran for 16h; Heating;
Stage #2: triisopropylsilyl chloride In tetrahydrofuran for 6h; Heating;
80%

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