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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

2-Propanone, 1-hydroxy-1-phenyl-, (1S)- CAS NO.53439-91-1

Cas:53439-91-1

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

L-Phenylacetyl Carbinol CAS 53439-91-1

Cas:53439-91-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

L-Phenylacetyl Carbinol CAS:53439-91-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

L-Phenylacetyl Carbinol CAS:53439-91-1

Cas:53439-91-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

Lonwin Chemical Group Limited

L-Phenylacetyl Carbinol CAS: 53439-91-1 Specification Product Name: L-Phenylacetyl Carbinol Synonyms: L-Phenylacetyl Carbinol (~80% ee) CAS: 53439-91-1 MF: C9H10O2 MW: 150.1745 EI

Factory supply L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:1 Kilogram

Negotiable

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

L-Phenylacetylcarbinol

Cas:53439-91-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used in organic syn

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

L-Phenylacetylcarbinol cas no. 53439-91-1 98%

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

L-Phenylacetylcarbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary and sec

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Other

inquiry

Shandong Mopai Biotechnology Co., LTD

best seller Application:API

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 729 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:intermediate

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

The factory supplies Application:manufacturing supplies

2-Propanone,1-hydroxy-1-phenyl-,(1S)-

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Taizhou Longyu Chemical Co., Ltd

Seeking Development with Quality and Promoting with ReputationOccupy the market with services and compete for benefits with efficiencyTaizhou Longyu Chemical Co., Ltd. is a modern private enterprise that integrates research and development, productio

L-Phenylacetyl Carbinol

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

hdzhl co., ltd

HDZHL Co., LTD. specializing in the production of research and development of pharmaceutical intermediates with high quality price concessions, welcomed the new and old customers advisory purchase, companies invest large fund and brain research f

(S)-PAC

Cas:53439-91-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Fine Chemicals Co., Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHenan Fine Chemicals Co., LTD. is a diversified technology - oriented integrated company, which mainly concentrates on fine chemicals. Our company is committed to becom

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

2-Propanone, 1-hydroxy-1-phenyl-, (1S)-

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the L-Phenylacetyl Carbinol (~80% ee), CAS:53439-91-1 with the most competitive price and

L-Phenylacetyl Carbinol (~80% ee)

Cas:53439-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With Arthrobacter sp. TS-15 recombinant pseudoephedrine dehydrogenase; NADH In aq. phosphate buffer at 25℃; pH=7.5; Kinetics; Green chemistry; Enzymatic reaction; enantioselective reaction;99%
3-Hydroxy-3-methyl-2-butanone
115-22-0

3-Hydroxy-3-methyl-2-butanone

benzaldehyde
100-52-7

benzaldehyde

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With acetoin:dichlorophenolindophenol oxidoreductase from Bacillus licheniformis; thiamine diphosphate; magnesium sulfate In aq. phosphate buffer; dimethyl sulfoxide at 30℃; for 24h; pH=6.5; Catalytic behavior; Solvent; Benzoin Condensation; Green chemistry; Enzymatic reaction; enantioselective reaction;84%
With thiamine diphosphate dependent acetoin:dichlorophenolindophenol oxidoreductase In aq. phosphate buffer; dimethyl sulfoxide at 30℃; for 48h; pH=6.5; Enzymatic reaction;
(2S,6R,7S,8aR)-7-Allyl-6-benzyl-6,8a-dimethyl-3-methylene-2-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one
1026422-63-8

(2S,6R,7S,8aR)-7-Allyl-6-benzyl-6,8a-dimethyl-3-methylene-2-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one

A

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

B

(3R,4S)-4-Allyl-3-benzyl-3,6-dimethyl-3,4-dihydro-1H-pyridin-2-one

(3R,4S)-4-Allyl-3-benzyl-3,6-dimethyl-3,4-dihydro-1H-pyridin-2-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In tetrahydrofuran; water Heating;A n/a
B 76%
3-Hydroxy-3-methyl-2-butanone
115-22-0

3-Hydroxy-3-methyl-2-butanone

benzaldehyde
100-52-7

benzaldehyde

A

3,4-dihydroxy-3,4-dimethylpentan-2-one

3,4-dihydroxy-3,4-dimethylpentan-2-one

B

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

C

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With acetoin:dichlorophenolindophenol oxidoreductase from Bacillus licheniformis; thiamine diphosphate; magnesium sulfate In aq. phosphate buffer; dimethyl sulfoxide at 30℃; for 12h; pH=6.5; Benzoin Condensation; Green chemistry; Enzymatic reaction; enantioselective reaction;A 2%
B n/a
C n/a
methyl magnesium iodide
917-64-6

methyl magnesium iodide

(R)-2-phenyl-2-(trimethylsiloxy)acetonitrile
120443-82-5

(R)-2-phenyl-2-(trimethylsiloxy)acetonitrile

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With hydrogenchloride 1.) ether, reflux, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
With sulfuric acid 1.) ether, reflux, 4 h; 2.) 0 deg C, 8 h; Yield given. Multistep reaction. Yields of byproduct given;
1-phenyl-2-trimethylsiloxy-1-propene
43108-63-0

1-phenyl-2-trimethylsiloxy-1-propene

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With (+)-(2S,8aS)-(camphorylsulfonyl)oxaziridine; methyllithium 1.) HMPA, THF, 0 deg C, 1h; 2.) -78 deg C; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
1-phenyl-acetone
103-79-7

1-phenyl-acetone

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With (+)-(2S,8aS)-(camphorylsulfonyl)oxaziridine; lithium diisopropyl amide 1.) HMPA, THF, -78 deg C; 2.) HMPA, -78 deg C; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
With (+)-(2S,8aS)-(camphorylsulfonyl)oxaziridine; sodium hexamethyldisilazane 1.) THF, HMPA, -78 deg C, 30 min, 2.) -78 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
With Bacillus megaterium cytochrome P450-BM3 V78F mutant Reagent/catalyst; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
With Bacillus megaterium cytochrome P450-BM3 A328R mutant Catalytic behavior; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

2-hydroxypropiophenone
5650-40-8

2-hydroxypropiophenone

B

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

C

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With NAD; isopropyl alcohol In hexane; water Ambient temperature; PED alcohol dehydrogenase, phosphate buffer pH 7.1; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
In water at 30℃; Product distribution; racemization;
(Z)-1-phenyl-2-(trimethylsiloxy)propene
19980-24-6

(Z)-1-phenyl-2-(trimethylsiloxy)propene

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With sodium hypochlorite; 4-Phenylpyridine 1-oxide; phosphate buffer; 5,5'-MeO-substituted (R,R)-(salen)Mn(III) In dichloromethane at 0℃; Mechanism; other silyl enol ethers and silyl ketene acetals; var. 5,5'-substituted (salen)Mn(III) complexes;
With sodium hypochlorite; 4-Phenylpyridine 1-oxide; phosphate buffer; 5,5'-MeO-substituted (R,R)-(salen)Mn(III) In dichloromethane at 0℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With sodium hypochlorite; 4-Phenylpyridine 1-oxide; phosphate buffer; 5,5'-tBu-substituted (R,R)-(salen)Mn(III) In dichloromethane at 0℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(Z)-1-phenyl-2-tert-butyldimethylsiloxy-1-propene
201738-82-1

(Z)-1-phenyl-2-tert-butyldimethylsiloxy-1-propene

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With sodium hypochlorite; 4-Phenylpyridine 1-oxide; phosphate buffer; 5,5'-tBu-substituted (R,R)-(salen)Mn(III) In dichloromethane at 0℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With hydrogen; Cinchonidin; Pt/Al2O3 In dichloromethane at 25℃; under 3750.3 Torr; Product distribution; Further Variations:; Catalysts;
With hydrogen; Cinchonidin; Pt/Al2O3 In ethyl acetate at 15℃; under 900.072 - 4875.39 Torr; Kinetics; Product distribution; Further Variations:; Catalysts; Pressures;
With Pt/Al2O3; hydrogen; Cinchonidin In toluene at 25℃; under 3750.3 Torr; Title compound not separated from byproducts;
1-phenylpropadiene
2327-99-3

1-phenylpropadiene

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With β-AD mix Sharpless asymmetric dihydroxylation;
With α-AD mix {K4[Fe(CN)6], OsO4, Na2CO3, (DHQ)2-PHAL} Sharpless asymmetric dihydroxylation;
3-phenylpentane-2,4-dione
5910-25-8

3-phenylpentane-2,4-dione

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Stage #1: 3-phenylpentane-2,4-dione With α-D-glucose 6-phosphate; Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase; oxygen; Thermobifida fusca phenylacetone monooxygenase; NADPH at 25℃; for 1.5h; pH=7.5; Baeyer-Villiger oxidation;
Stage #2: With water Title compound not separated from byproducts;
1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

(1S,2R)-1,2-dihydroxy-1-phenylpropane

(1S,2R)-1,2-dihydroxy-1-phenylpropane

B

(1R,2S)-1-phenylpropane-1,2-diol
40421-52-1

(1R,2S)-1-phenylpropane-1,2-diol

C

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

D

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With 11-(triethylsilyl)-10,11-dihydrocinchonidine; hydrogen; Pt/Al2O3 In toluene at 15℃; under 7500.6 Torr; Kinetics; Further Variations:; Reagents;
benzaldehyde
100-52-7

benzaldehyde

acetaldehyde
75-07-0

acetaldehyde

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

C

(R)-2-hydroxy-1-phenylpropan-1-one
5650-40-8, 65646-07-3, 91840-95-8, 65646-06-2

(R)-2-hydroxy-1-phenylpropan-1-one

D

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With ketoacid decarboxylase In phosphate buffer; dimethyl sulfoxide at 30℃; pH=6.8; Title compound not separated from byproducts.;
1-Phenyl-2-propyn-1-ol
4187-87-5

1-Phenyl-2-propyn-1-ol

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 63 percent / LAH; AlCl3
2: α-AD mix
View Scheme
benzaldehyde
100-52-7

benzaldehyde

methylacetylene metal salt

methylacetylene metal salt

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 63 percent / LAH; AlCl3
2: α-AD mix
View Scheme
benzyl bromide
100-39-0

benzyl bromide

potassium-compound of propionic acid-<1-methyl-2-oxo-propylidenehydrazide>

potassium-compound of propionic acid-<1-methyl-2-oxo-propylidenehydrazide>

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) LDA / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 2 h
2: 1.) LDA / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 2 h
3: MeLi
4: TsOH / tetrahydrofuran; H2O / Heating
View Scheme
Multi-step reaction with 3 steps
1: 1.) LDA / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 2 h
2: MeLi
3: TsOH / tetrahydrofuran; H2O / Heating
View Scheme
(2S,3S,7S,8aR)-7-Allyl-6-benzyl-3-methoxymethyl-8a-methyl-2-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one

(2S,3S,7S,8aR)-7-Allyl-6-benzyl-3-methoxymethyl-8a-methyl-2-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) LDA / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 2 h
2: MeLi
3: TsOH / tetrahydrofuran; H2O / Heating
View Scheme
(2S,3S,6R,7S,8aR)-7-Allyl-6-benzyl-3-methoxymethyl-6,8a-dimethyl-2-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one
203710-53-6

(2S,3S,6R,7S,8aR)-7-Allyl-6-benzyl-3-methoxymethyl-6,8a-dimethyl-2-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: MeLi
2: TsOH / tetrahydrofuran; H2O / Heating
View Scheme
(R)-Mandelonitrile
10020-96-9

(R)-Mandelonitrile

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) imidazole / 1.) DMF, 0 deg C, 15 min; 2.) 1 h, RT, water
2: 2.) H2SO4 / 1.) ether, reflux, 4 h; 2.) 0 deg C, 8 h
View Scheme
Multi-step reaction with 2 steps
1: 100 percent / imidazole, DMAP / diethyl ether
2: 2.) 2 M HCl / 1.) ether, reflux, 2 h
View Scheme
benzaldehyde
100-52-7

benzaldehyde

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: oxynitralase, buffer ( pH=5.4 ) / ethanol; acetic acid / 0.67 h / 0 °C
2: 1.) imidazole / 1.) DMF, 0 deg C, 15 min; 2.) 1 h, RT, water
3: 2.) H2SO4 / 1.) ether, reflux, 4 h; 2.) 0 deg C, 8 h
View Scheme
1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

C

(R)-2-hydroxy-1-phenylpropan-1-one
5650-40-8, 65646-07-3, 91840-95-8, 65646-06-2

(R)-2-hydroxy-1-phenylpropan-1-one

D

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With hydrogen; cinchonidine In cyclohexane at 24.84℃; under 30003 Torr; Kinetics; Concentration;
With 1% Pt on cinchonidine immobilized γ-Al2O3 catalyst In cyclohexane at 24.84℃; under 30003 Torr; Catalytic behavior; Kinetics; Reagent/catalyst; Solvent; Pressure; Concentration; enantioselective reaction;A n/a
B n/a
C n/a
D n/a
With hydrogen In cyclohexane at 24.84℃; under 15001.5 Torr; Reagent/catalyst; enantioselective reaction;A n/a
B n/a
C n/a
D n/a
1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

(1R,2S)-1-phenylpropane-1,2-diol
40421-52-1

(1R,2S)-1-phenylpropane-1,2-diol

B

(1R,2R)-1-phenylpropane-1,2-diol
40421-51-0

(1R,2R)-1-phenylpropane-1,2-diol

C

(1S,2S)-1-phenyl-1,2-propanediol
88196-06-9

(1S,2S)-1-phenyl-1,2-propanediol

D

(1S,2R)-1-phenylpropane-1,2-diol
40560-98-3

(1S,2R)-1-phenylpropane-1,2-diol

E

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

G

(R)-2-hydroxy-1-phenylpropan-1-one
5650-40-8, 65646-07-3, 91840-95-8, 65646-06-2

(R)-2-hydroxy-1-phenylpropan-1-one

H

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With hydrogen; cinchonidine In cyclohexane at 25℃; under 30003 Torr; Kinetics; Reagent/catalyst; Autoclave; enantioselective reaction;
1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

2-hydroxypropiophenone
5650-40-8

2-hydroxypropiophenone

B

1-phenyl-1,2-propandiol
1855-09-0

1-phenyl-1,2-propandiol

C

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

D

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With hydrogen In cyclohexane under 30003 Torr; Kinetics; Time; optical yield given as %ee; enantioselective reaction;
benzaldehyde
100-52-7

benzaldehyde

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

A

(R)-1-hydroxy-1-phenyl-2-propanone
1798-60-3

(R)-1-hydroxy-1-phenyl-2-propanone

B

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With Escherichia coli K12 sucA gene In dimethyl sulfoxide pH=8; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
With (S)-selective carboligase ApPDC variant E469G In aq. phosphate buffer at 25℃; for 48h; pH=7; Enzymatic reaction; Overall yield = 95 %;A n/a
B n/a
(1RS,2SR)-1-phenylpropane-1,2-diol
40421-52-1

(1RS,2SR)-1-phenylpropane-1,2-diol

B

(R)-2-hydroxy-1-phenylpropan-1-one
5650-40-8, 65646-07-3, 91840-95-8, 65646-06-2

(R)-2-hydroxy-1-phenylpropan-1-one

C

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With N-bromophthalimide; 1-(3,5-bis(trifluoromethyl)phenyl)-3-((S)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methyl)urea In chloroform at 0℃; for 24h; Overall yield = 89 %; enantioselective reaction;A n/a
B n/a
C n/a
1-phenyl-acetone
103-79-7

1-phenyl-acetone

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
With Bacillus megaterium cytochrome P450-BM3 V78W mutant Catalytic behavior; Enzymatic reaction; enantioselective reaction;n/a
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thiamine diphosphate; acetoin:dichlorophenolindophenol oxidoreductase from Bacillus licheniformis; magnesium sulfate / aq. phosphate buffer; dimethyl sulfoxide / 24 h / 32 °C / pH 6.5 / Green chemistry; Enzymatic reaction
2: thiamine diphosphate; acetoin:dichlorophenolindophenol oxidoreductase from Bacillus licheniformis; magnesium sulfate / aq. phosphate buffer; dimethyl sulfoxide / 24 h / 30 °C / pH 6.5 / Green chemistry; Enzymatic reaction
View Scheme
(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

(1S,2S)-1-phenyl-1,2-propanediol
88196-06-9

(1S,2S)-1-phenyl-1,2-propanediol

Conditions
ConditionsYield
With acetylacetoin reductase; NAD; sodium formate; formate dehydrogenase form Candida boidinii In aq. phosphate buffer; dimethyl sulfoxide at 30℃; for 10h; pH=6.5; Enzymatic reaction; stereoselective reaction;84%
(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

(1R)-2-(aminooxy)-1-phenylethanol
405146-15-8

(1R)-2-(aminooxy)-1-phenylethanol

(S)-1-Hydroxy-1-phenyl-propan-2-one O-((R)-2-hydroxy-2-phenyl-ethyl)-oxime
405146-35-2

(S)-1-Hydroxy-1-phenyl-propan-2-one O-((R)-2-hydroxy-2-phenyl-ethyl)-oxime

Conditions
ConditionsYield
dehydration;
(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

(1S,2S)-2-((R)-2-Hydroxy-2-phenyl-ethoxyamino)-1-phenyl-propan-1-ol

(1S,2S)-2-((R)-2-Hydroxy-2-phenyl-ethoxyamino)-1-phenyl-propan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dehydration
2: ZrCl4; NaBH4 / diethyl ether; CH2Cl2 / 24 h / 0 °C
View Scheme
(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

(1S,2R)-2-((R)-2-Hydroxy-2-phenyl-ethoxyamino)-1-phenyl-propan-1-ol
405146-52-3

(1S,2R)-2-((R)-2-Hydroxy-2-phenyl-ethoxyamino)-1-phenyl-propan-1-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dehydration
2: ZrCl4; NaBH4 / diethyl ether; CH2Cl2 / 24 h / 0 °C
View Scheme
(S)-phenylacetylcarbinol
53439-91-1

(S)-phenylacetylcarbinol

(4S,5S)-3-((R)-2-Hydroxy-2-phenyl-ethoxy)-4-methyl-5-phenyl-oxazolidin-2-one

(4S,5S)-3-((R)-2-Hydroxy-2-phenyl-ethoxy)-4-methyl-5-phenyl-oxazolidin-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dehydration
2: ZrCl4; NaBH4 / diethyl ether; CH2Cl2 / 24 h / 0 °C
3: benzene / Heating
View Scheme
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