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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

High purity 3,3-Dimethyl acrylic acid 99% TOP1 supplier in China

Cas:541-47-9

Min.Order:100 Gram

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 3,3-Dimethylacrylicacid( 541-47-9)

Cas:541-47-9

Min.Order:100 Gram

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Shandong Xinhua Pharmaceutical Co.,Ltd

Shandong Xinhua Pharmaceutical Company Limited ("Shandong Xinhua") is in an leading position in the manufacturing technology and capacity for antipyretics and analgesics in China and is an important manufacturer in China for the drugs

Jinan Finer Chemical Co., Ltd

Product website: http://www.finerchem.com Product Name 3,3-Dimethylacrylic acid CAS No. 541-47-9 Appeara

3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

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Ality Chemical Corporation

We are manufacturer of this product. If you are looking for the material's manufacturer or supplier in China, Ality Group is your best choice. Specifications of our Senecioic acid CAS 541-47-9: Items Spec

Factory Supply Senecioic acid

Cas:541-47-9

Min.Order:1 Gram

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ----------------------------------------------------------------------------------------------

High purity Various Specifications 3,3-Dimethylacrylic acid CAS:541-47-9

Cas:541-47-9

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,3-Dimethylacrylic Acid supplier in China

Cas:541-47-9

Min.Order:0 Metric Ton

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:1 Kilogram

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 541-47-9 2-Butenoic acid,3-methyl-

Cas:541-47-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards. 2. Now we have established lon

3,High quality 3-Dimethylacrylic acid,3-methyl-2-butenoic acid 99% 541-47-9 manufacturer

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Chemwill Asia Co., Ltd.

CHemwill -- 3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

1 Factory price 2 Good service 3 High quality 4 Prompt delivery Appearance:white crystals Storage:Kept in dry and cool place and from sunlight; Kept the packing intact. Package: 25kg plastic woven bag with inner linning. Application:Fine Chem

CAS No. 541-47-9 (2-Butenoic acid,3-methyl- )

Cas:541-47-9

Min.Order:100 Kilogram

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Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

3, 3-Dimethylacrylic Acid CAS 541-47-9

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

541-47-9 3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 541-47-9 with best quality

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality 3,3-Dimethylacrylic Acid CAS 541-47-9

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3,3-Dimethyl acrylic acid/High quality/Best price/In stock

Cas:541-47-9

Min.Order:10 Kilogram

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Henan Sinotech Import&Export Corporation

Name : 3,3-dimethylacrylic acid Synonyms : 3-methyl-2-butenoic acid; 3-methylcrotonic acid; senecioic acid; 3,3-dimethylacrylic acid Molecular Structure : 3,3-dimethylacrylic acid; 3-methyl-2-butenoic acid; 3-methylcrotonic acid; senecioic

3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Butenoic acid,3-methyl- 541-47-9

Cas:541-47-9

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $20.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

3,3-Dimethylacrylic acid CAS: 541-47-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

3,3-Dimethylacrylic acid CAS: 541-47-9

Cas:541-47-9

Min.Order:1 Gram

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Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Butenoic acid,3-methyl-

Cas:541-47-9

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big custo

3, 3-Dimethylacrylic Acid CAS 541-47-9

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Butenoic acid,3-methyl-

Cas:541-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,3-Dimethylacrylic Acid

Cas:541-47-9

Min.Order:0

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

3,3-Dimethylacrylic acid 541-47-9

Cas:541-47-9

Min.Order:100 Gram

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Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,3-Dimethyl Acrylic Acid (Senecioic Acid)

Cas:541-47-9

Min.Order:0 Metric Ton

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3,3-DIMETHYLACRYLIC ACID

Cas:541-47-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,3-Dimethylacrylic acid

Cas:541-47-9

Min.Order:0

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Synthetic route

3-Benzenesulfinyl-3-methyl-butyric acid

3-Benzenesulfinyl-3-methyl-butyric acid

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
In various solvent(s) for 0.0166667h; Irradiation;99%
3,3-dimethyl acrylaldehyde
107-86-8

3,3-dimethyl acrylaldehyde

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With 4H3N*4H(1+)*CuMo6O18(OH)6(4-); water; oxygen; sodium carbonate at 50℃; under 760.051 Torr; for 12h;98%
With copper acetylacetonate; oxygen; sodium hydroxide; 1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene In water at 50℃; under 760.051 Torr; for 12h; Sealed tube;91%
With Iron(III) nitrate nonahydrate; oxygen; sodium 2,2,2-trifluoroacetate In ethyl acetate at 25℃; under 760.051 Torr; for 16h;38%
(Z)-3-iodobut-2-enoic acid
34450-60-7

(Z)-3-iodobut-2-enoic acid

methylmagnesium bromide
75-16-1

methylmagnesium bromide

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
Stage #1: methylmagnesium bromide With zinc dibromide In diethyl ether at 25℃;
Stage #2: (Z)-3-iodobut-2-enoic acid; dichloro bis(acetonitrile) palladium(II) In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide at 25℃; for 12h;
95%
carbon monoxide
201230-82-2

carbon monoxide

3-hydroxy-2-methyl-1-propene
513-42-8

3-hydroxy-2-methyl-1-propene

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
1,4-di(diphenylphosphino)-butane; bis(dibenzylideneacetone)-palladium(0) In 1,2-dimethoxyethane at 190℃; under 30400 Torr; for 48h;92%
3-methyl-2-buten-1-ol
556-82-1

3-methyl-2-buten-1-ol

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With potassium phosphate; carbon dioxide; CrH6Mo6O24(3-)*3H3N*3H(1+) In dimethyl sulfoxide at 80℃; under 750.075 Torr; for 24h; Green chemistry;89%
Multi-step reaction with 2 steps
1: 1-hydroxy-1,2-benziodoxole-3(1H)-one-1-oxide / dimethylsulfoxide / 16 h / 20 °C
2: NaOH; H2O / dimethylsulfoxide
View Scheme
3-methyl-2-buten-1-ol
556-82-1

3-methyl-2-buten-1-ol

A

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

B

3,3-dimethyl acrylaldehyde
107-86-8

3,3-dimethyl acrylaldehyde

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium acetate; 4,7-di-(NaSO3Ph)-[1.10]phenanthroline-Pd(OAc)2 In water at 100℃; under 22502.3 Torr; for 10h; pH=6.5 - 11.5;A n/a
B 88%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; titanium(IV) oxide In benzotrifluoride under 750.075 Torr; for 8h; Irradiation;
With oxygen In water at 20℃; under 760.051 Torr; for 336h; pH=6.5 - 7;
concentrated sodium bisulfite

concentrated sodium bisulfite

4-methyl-pent-3-en-2-one
141-79-7

4-methyl-pent-3-en-2-one

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With sodium hypochlorite In chloroform; water80%
3-Hydroxy-3-methylbutyric acid
625-08-1

3-Hydroxy-3-methylbutyric acid

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 100 - 110℃; for 1h;76%
With sulfuric acid
With sulfuric acid durch Destillation;
2-methyl-1-propenylbromide
3017-69-4

2-methyl-1-propenylbromide

carbon dioxide
124-38-9

carbon dioxide

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With (2,2'-bipyridine)nickel(II) dibromide; tetrabutylammonium tetrafluoroborate In N,N-dimethyl-formamide at -10℃; electrolysis with 3 F/mol at 10 mA/cm2; Pt cathode; Mg anode;64%
With tetrabutylammonium tetrafluoroborate; (2,2'-bipyridine)nickel(II) dibromide In N,N-dimethyl-formamide at -10℃; Product distribution; electrolysis with 3 F/mol at 10 mA/cm2; Pt cathode, Mg anode; without/with catalyst;64%
dimethyl 6-hydroxy-11-(1-methylethylidene)-9,10-dioxa-4,5-diazatricyclo[6.2.1.02,7]undec-3-ene-3,6-dicarboxylate

dimethyl 6-hydroxy-11-(1-methylethylidene)-9,10-dioxa-4,5-diazatricyclo[6.2.1.02,7]undec-3-ene-3,6-dicarboxylate

A

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

B

pyridazine-3,6-dicarboxylic acid dimethyl ester
2166-24-7

pyridazine-3,6-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With bis-[(trifluoroacetoxy)iodo]benzene In chloroform at -40 - 20℃;A 57%
B n/a
4-methyl-pent-3-en-2-one
141-79-7

4-methyl-pent-3-en-2-one

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With sodium hypochlorite; lithium hypochlorite In ethanol at 77℃; for 8h;56%
With sodium hydroxide; sodium bromite; sodium bromide In water at 0 - 45℃; for 2h;40%
With potassium hydroxide; iodine
2-methyl-1-propenylbromide
3017-69-4

2-methyl-1-propenylbromide

carbon monoxide
201230-82-2

carbon monoxide

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With [bmim]PF6; triethylamine; bis-triphenylphosphine-palladium(II) chloride In water at 100℃; under 15001.2 Torr; for 20h;56%
With sodium hydroxide; cetyltrimethylammonim bromide; nickel cyanide In toluene at 95℃; under 735.5 Torr; for 8h;45%
4,4-dimethyloxetan-2-one
1823-52-5

4,4-dimethyloxetan-2-one

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With sulfuric acid
ethyl 2-bromoisovalerate
609-12-1

ethyl 2-bromoisovalerate

A

α-ethoxy-isovaleric acid ethyl ester
109989-35-7

α-ethoxy-isovaleric acid ethyl ester

B

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With ethanol; sodium ethanolate Bildung des Aethylesters;
ethyl 2-bromoisovalerate
609-12-1

ethyl 2-bromoisovalerate

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With N,N-diethylaniline Bildung des Aethylesters;
With quinoline at 170 - 175℃; und dann Erhitzen auf185-190grad;Bildung des Aethylesters;
With quinoline at 225℃; Bildung des Aethylesters;
With potassium hydroxide
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

acetic anhydride
108-24-7

acetic anhydride

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

4-methyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester
101080-10-8

4-methyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester

A

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

B

4-Methylpyrazol-3-carbonsaeure-methylester
68809-58-5

4-Methylpyrazol-3-carbonsaeure-methylester

Conditions
ConditionsYield
at 140 - 190℃;
ethyl isodehydroacetate
3385-34-0

ethyl isodehydroacetate

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With potassium hydroxide
iodoform
75-47-8

iodoform

sodium isobutoxide
13259-29-5

sodium isobutoxide

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

iodoform
75-47-8

iodoform

sodium isobutoxide
13259-29-5

sodium isobutoxide

A

formic acid
64-18-6

formic acid

B

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

C

α-isobutoxy-isobutyric acid
17860-06-9

α-isobutoxy-isobutyric acid

D

isobutyric Acid
79-31-2

isobutyric Acid

Conditions
ConditionsYield
Produkt 5-8:Methylisobutylaether;Methylendiisobutylaether;Isobutylen;1,2-Diisobutoxy-2-methyl-propan-1-ol;
phorone
504-20-1

phorone

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
bei unvollstaendiger Ozonisation entstandenes Produkt reagiert mit Wasser;
With chloroform; ozone und Umsetzen das Reaktionsprodukt mit Wasser;
ethyl 3-hydroxy-3-methylbutanoate
18267-36-2

ethyl 3-hydroxy-3-methylbutanoate

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
durch Wasserabspaltung und Verseifung des Reaktionsprodukts;
With formic acid
With potassium pyrosulfate at 140 - 145℃; Bildung des Aethylesters;
Verseifen des Esters nach Wasserabspaltung;
With phosphorus trichloride Bildung des Aethylesters;
ethyl 2-acetyl-3-methylbut-2-enoate
35044-52-1

ethyl 2-acetyl-3-methylbut-2-enoate

A

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

B

acetic acid
64-19-7

acetic acid

Conditions
ConditionsYield
With barium dihydroxide
2-bromoisovaleric acid
10323-40-7, 565-74-2

2-bromoisovaleric acid

sodium methylate
124-41-4

sodium methylate

A

2-methoxy-3-methylbutanoic acid
66018-25-5

2-methoxy-3-methylbutanoic acid

B

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

2-bromoisovaleric acid
10323-40-7, 565-74-2

2-bromoisovaleric acid

A

2-methoxy-3-methylbutanoic acid
66018-25-5

2-methoxy-3-methylbutanoic acid

B

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With sodium methylate
2-bromoisovaleric acid
10323-40-7, 565-74-2

2-bromoisovaleric acid

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
With quinoline zunaechst auf 140-150grad und dann auf 165-170grad;
With ammonium hydroxide nachfolgendes Zerlegen mit Baryt und Ansaeuern mit Schwefelsaeure;
1,1,1-trichloro-3,3-dimethyl-3-bromopropane
23153-21-1

1,1,1-trichloro-3,3-dimethyl-3-bromopropane

sodium ethanolate
141-52-6

sodium ethanolate

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3-methylbut-2-enal
100191-34-2

3-methylbut-2-enal

A

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

B

4-methyl-2-oxo-pent-3-enoic acid
143255-96-3

4-methyl-2-oxo-pent-3-enoic acid

Conditions
ConditionsYield
With potassium hydroxide; ethanol; silver nitrate
4-chloro-2-methylbut-3-yn-2-ol
29552-15-6

4-chloro-2-methylbut-3-yn-2-ol

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Conditions
ConditionsYield
ueber 4-Chlor-2-methyl-but-1-en-3-in;
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

tert-butylisonitrile
119072-55-8, 7188-38-7

tert-butylisonitrile

isovaleraldehyde
590-86-3

isovaleraldehyde

1-(tert-butylamino)-4-methyl-1-oxopentan-2-yl 3-methylbut-2-enoate

1-(tert-butylamino)-4-methyl-1-oxopentan-2-yl 3-methylbut-2-enoate

Conditions
ConditionsYield
In water for 0.5h; Passerini reaction; Sonication; Cooling with ice;100%
In water at 25℃; Kinetics; Further Variations:; Solvents; Reagents; Passerini reaction;95%
In water at 20℃; Passerini reaction;86%
In dichloromethane at 25℃; for 18h; Kinetics; Product distribution; Further Variations:; Solvents; Passerini reaction;45%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

p-chlorobenzylisocyanide
39546-47-9

p-chlorobenzylisocyanide

isovaleraldehyde
590-86-3

isovaleraldehyde

C18H25ClN2O2
1262749-10-9

C18H25ClN2O2

Conditions
ConditionsYield
With ammonia In methanol; water at 130℃; for 1.5h; Ugi reaction; Microwave irradiation; microwave tube;100%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3,3-Dimethylacryloyl chloride
3350-78-5

3,3-Dimethylacryloyl chloride

Conditions
ConditionsYield
With oxalyl dichloride In dichloromethane at 20℃;99%
With thionyl chloride at 0℃; for 3h;96%
With thionyl chloride 1.) reflux, 1.3 h, 2.) room temperature, 2.5 h, 3.) reflux, 1 h;92%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

phenylmethanethiol
100-53-8

phenylmethanethiol

3-methyl-3-(phenylmethylthio)butanoic acid
7536-39-2

3-methyl-3-(phenylmethylthio)butanoic acid

Conditions
ConditionsYield
With hydrogenchloride In piperidine99%
With piperidine for 24h; Heating;90%
With piperidine for 22h; Heating;81%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

benzyl bromide
100-39-0

benzyl bromide

benzyl 3-methylbut-2-enoate
37526-89-9

benzyl 3-methylbut-2-enoate

Conditions
ConditionsYield
With potassium hydroxide; tetrabutylammomium bromide In chloroform for 18h; Heating;99%
With caesium carbonate In N,N-dimethyl-formamide87%
With potassium hydroxide; tetrabutylammomium bromide In chloroform; water for 18h; Reflux; Inert atmosphere;417 mg
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

benzyl alcohol
100-51-6

benzyl alcohol

benzyl 3-methylbut-2-enoate
37526-89-9

benzyl 3-methylbut-2-enoate

Conditions
ConditionsYield
tetrachlorobis(tetrahydrofuran)hafnium(IV) In benzene for 38h; Heating;99%
With iron(III)-acetylacetonate In 5,5-dimethyl-1,3-cyclohexadiene for 14h; Inert atmosphere; Reflux;95%
With TiO(acac)2 In xylene for 36h; Heating;93%
With di-tert-butyl-diazodicarboxylate; polymer-bound triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 12h; Mitsunobu reaction;87%
With di-tert-butyl-diazodicarboxylate; triphenylphosphine polystyrene beads In tetrahydrofuran at 20℃; for 12h; Mitsunobu reaction;87%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

(1R,2R,3S,6R,8R,9R)-3-methoxy-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.0(2,6)]dodecan-9-ol
102358-40-7

(1R,2R,3S,6R,8R,9R)-3-methoxy-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.0(2,6)]dodecan-9-ol

(1R,2R,3S,6R,8R,9R)-3-methoxy-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.0(2,6)]dodecan-9-yl 3-methylbut-2-enoate
102358-39-4

(1R,2R,3S,6R,8R,9R)-3-methoxy-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.0(2,6)]dodecan-9-yl 3-methylbut-2-enoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In toluene at 20℃; for 24h;99%
Stage #1: 3-Methylbutenoic acid; (1R,2R,3S,6R,8R,9R)-3-methoxy-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.0(2,6)]dodecan-9-ol With dmap; dicyclohexyl-carbodiimide In toluene at 0 - 20℃;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 9h;
6.5 mg
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3,5-Dimethylphenol
108-68-9

3,5-Dimethylphenol

4,4,5,7-tetramethyl-3,4-dihydrocoumarin
40662-14-4

4,4,5,7-tetramethyl-3,4-dihydrocoumarin

Conditions
ConditionsYield
With methanesulfonic acid In toluene at 85℃; for 4h; Inert atmosphere;99%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Trimethylhydroquinone
700-13-0

Trimethylhydroquinone

6-hydroxy-4,4,5,7,8-pentamethyl-3,4-dihydrocoumarin
40662-76-8

6-hydroxy-4,4,5,7,8-pentamethyl-3,4-dihydrocoumarin

Conditions
ConditionsYield
With methanethiosulfonic acid at 70℃; for 1.5h;98%
With methanesulfonic acid at 70℃; for 4h;87%
With methanesulfonic acid at 85℃; for 3h;85%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3-methyl-2-butenoic anhydride
34876-10-3

3-methyl-2-butenoic anhydride

Conditions
ConditionsYield
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane at 20℃; for 0.5h;98%
With potassium carbonate; 2-(4-nitrobenzenesulfonyl)-4,5-dichloropyridazin-3-one In tetrahydrofuran at 40℃; for 3h;92%
With triethylamine; trichloroacetonitrile; triphenylphosphine In dichloromethane at 20℃; for 4h;75%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

recorcinol
108-46-3

recorcinol

7-hydroxy-2,2-dimethyl-chroman-4-one
17771-33-4

7-hydroxy-2,2-dimethyl-chroman-4-one

Conditions
ConditionsYield
With phosphorus pentoxide In methanesulfonic acid at 70℃; for 0.333333h; Friedel-Crafts Acylation; Inert atmosphere; Microwave irradiation;98%
With methanesulfonic acid; phosphorus pentoxide at 70℃;96%
With methanesulfonic acid; phosphorus pentoxide at 70℃; for 0.5h;94%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

benzene
71-43-2

benzene

3-methyl-3-phenylbutanoic acid
1010-48-6

3-methyl-3-phenylbutanoic acid

Conditions
ConditionsYield
With aluminum (III) chloride at 5 - 20℃; for 0.333333h;98%
With aluminium trichloride at 65℃;94%
Stage #1: 3-Methylbutenoic acid; benzene; aluminum (III) chloride at 65℃;
Stage #2: With hydrogenchloride; water at 0℃; pH=< 2;
94%
Thiophene-2-thiol
7774-74-5

Thiophene-2-thiol

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3-methyl-3-(thiophene-2-thio)butyric acid
111190-17-1

3-methyl-3-(thiophene-2-thio)butyric acid

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran for 21h; Heating;98%
With triethylamine In tetrahydrofuran for 20h; Reflux; Inert atmosphere;63.35%
With triethylamine In tetrahydrofuran for 20h; Reflux; Inert atmosphere;63.35%
With triethylamine In tetrahydrofuran for 20h; Inert atmosphere; Reflux;63.35%
With triethylamine In tetrahydrofuran for 20h; Inert atmosphere; Reflux;63.4%
N-p-toluenesulfonylpyrrole
17639-64-4

N-p-toluenesulfonylpyrrole

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

4,5-dihydro-4,4-dimethyl-1-(4'-methylphenylsulfonyl)cyclopenta[b]pyrrol-6(1H)-one

4,5-dihydro-4,4-dimethyl-1-(4'-methylphenylsulfonyl)cyclopenta[b]pyrrol-6(1H)-one

Conditions
ConditionsYield
With {[Zn4(pdpa)2(H2O)8]*H2O}n; trifluoroacetic anhydride In 1,2-dichloro-ethane for 4h; Reagent/catalyst; Nazarov Cyclization; Reflux;98%
With C10H2N16(4-)*3H2O*4Ag(1+); trifluoroacetic anhydride In 1,2-dichloro-ethane for 5h; Reagent/catalyst; Nazarov Cyclization; Reflux;92%
With iron(III) chloride; trifluoroacetic anhydride In dichloromethane for 4h; Reflux;74%
With trifluoroacetic anhydride In 1,2-dichloro-ethane at 80℃; for 16h; Nazarov cyclization;51%
{TiMgCl6(C2H5O2CCH3)4}

{TiMgCl6(C2H5O2CCH3)4}

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Ti(4+)*Mg(2+)*4Cl(1-)*2(CH3)2CCHCO2(1-)*2C2H5O2CCH3={TiMgCl4((CH3)2CCHCO2)2(C2H5O2CCH3)2}

Ti(4+)*Mg(2+)*4Cl(1-)*2(CH3)2CCHCO2(1-)*2C2H5O2CCH3={TiMgCl4((CH3)2CCHCO2)2(C2H5O2CCH3)2}

Conditions
ConditionsYield
In dichloromethane dissolving (TiMgCl6(C2H5O2CCH3)4) (3.2 mmol) in CH2Cl2; addn. of (CH3)2CCHCO2H (6.5 mmol) against a stream of N2; warming to 35°C for 1.5 h; cooling to room temp.;; pumping off solvent; stirring with hexane; filtering, drying in vac. for 2 h; elem. anal.;;98%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

(3-isopropylene-2,2-dimethylcyclobutyl)methanol

(3-isopropylene-2,2-dimethylcyclobutyl)methanol

(2,2-dimethyl-3-(propan-2-ylidene)cyclobutyl)methyl 3-methylbut-2-enoate

(2,2-dimethyl-3-(propan-2-ylidene)cyclobutyl)methyl 3-methylbut-2-enoate

Conditions
ConditionsYield
With dmap; diisopropyl-carbodiimide In dichloromethane at 40℃; for 24h;98%
methanol
67-56-1

methanol

3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

Methyl 3,3-dimethylacrylate
924-50-5

Methyl 3,3-dimethylacrylate

Conditions
ConditionsYield
With [1-(3-sulfonic acid)]propyl-3-methylimidazolium hydrogen sulfate for 3h; Reflux; Green chemistry;97.8%
With sulfuric acid95%
With sulfuric acid for 16h; Heating;92%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

<(4-nitrophenyl)oxy>sulfonyl isocyanate
73748-48-8

<(4-nitrophenyl)oxy>sulfonyl isocyanate

(4-nitrophenyl)-N-(3-methylbut-2-enoyl)sulfamate
1070898-27-9

(4-nitrophenyl)-N-(3-methylbut-2-enoyl)sulfamate

Conditions
ConditionsYield
With triethylamine In toluene at 20℃; for 0.5h;97%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

recorcinol
108-46-3

recorcinol

1-(2',4'-dihydroxyphenyl)-3-methyl-1-oxo-2-butene
99323-00-9

1-(2',4'-dihydroxyphenyl)-3-methyl-1-oxo-2-butene

Conditions
ConditionsYield
With zinc(II) chloride; trichlorophosphate at 25℃; for 2h;96.9%
With aluminium trichloride; trichlorophosphate for 5h; Ambient temperature;92%
Stage #1: 3-Methylbutenoic acid With boron trifluoride diethyl etherate; trichlorophosphate at 0℃; for 0.25h; Substitution;
Stage #2: recorcinol at 25℃; for 5h; Acylation; Friedel-Crafts reaction;
80%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

thiophenol
108-98-5

thiophenol

3-methyl-3-phenylsulfanyl-butanoic acid
64793-86-8

3-methyl-3-phenylsulfanyl-butanoic acid

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride at 50℃; for 24h;96%
With iodine at 50℃; for 5h; Michael reaction;95%
With piperidine at 103 - 107℃; for 19h;87%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

3-Methyl-but-2-enoic acid methylsulfanylmethyl ester
72064-63-2

3-Methyl-but-2-enoic acid methylsulfanylmethyl ester

Conditions
ConditionsYield
With t-butyl bromide; sodium hydrogencarbonate at 25 - 30℃; for 24h;95%
With t-butyl bromide; sodium hydrogencarbonate
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3-Phenyl-1-propanol
122-97-4

3-Phenyl-1-propanol

3-phenylpropyl 3-methyl-2-butenoate
56500-48-2

3-phenylpropyl 3-methyl-2-butenoate

Conditions
ConditionsYield
With chloro-trimethyl-silane; silver perchlorate; titanium tetrachloride; 4-(trifluoromethyl)benzoic anhydride In dichloromethane; toluene at 20℃; for 12h;95%
With 2-fluoro-1-ethylpyridinium tetrafluoroborate; cesium fluoride 1) methylene chloride, 30 min, r.t., 2) methylene chloride, overnight, r.t.; Yield given. Multistep reaction;
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

methoxyhydroquinone
824-46-4

methoxyhydroquinone

2,2-Dimethyl-6-hydroxy-7-methoxy-4-chromanone
74094-44-3

2,2-Dimethyl-6-hydroxy-7-methoxy-4-chromanone

Conditions
ConditionsYield
With methanesulfonic acid at 70℃; for 12h;95%
With methanesulfonic acid; phosphorus pentoxide at 70℃; for 0.5h;91%
With methanesulfonic acid; phosphorus pentoxide91%
With trifluoroacetic acid at 80℃; for 1h;84%
With PPA 1.) 30 deg C, 4 h, 100 deg C, 1 h;48%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

3-Ethoxy-4-methoxybenzenethiol
111424-64-7

3-Ethoxy-4-methoxybenzenethiol

3-(3-Ethoxy-4-methoxy-phenylsulfanyl)-3-methyl-butyric acid
111424-50-1

3-(3-Ethoxy-4-methoxy-phenylsulfanyl)-3-methyl-butyric acid

Conditions
ConditionsYield
With piperidine at 103 - 107℃; for 18h;95%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

4-bromo-3-(bromomethyl)but-2-enoic acid
75887-43-3

4-bromo-3-(bromomethyl)but-2-enoic acid

Conditions
ConditionsYield
With N-Bromosuccinimide; Perbenzoic acid In tetrachloromethane for 4h; Heating;95%
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane for 4h; Reflux;95%
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane Reflux;95%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

4-methoxy-phenol
150-76-5

4-methoxy-phenol

4'-methoxyphenyl 3-methylbut-2-enoate
84346-76-9

4'-methoxyphenyl 3-methylbut-2-enoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 6h; Ambient temperature;95%
With aluminium trichloride; trichlorophosphate for 0.5h; Ambient temperature; Yield given;
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

rac-methylbenzylamine
618-36-0

rac-methylbenzylamine

A

N-benzyl-3,3-dimethylacrylic amide
67264-80-6

N-benzyl-3,3-dimethylacrylic amide

B

3-Methyl-but-2-enoic acid (1-phenyl-ethyl)-amide
98379-81-8

3-Methyl-but-2-enoic acid (1-phenyl-ethyl)-amide

Conditions
ConditionsYield
With potassium hydroxide; bis(o-nitrophenyl)phenylphosphonate; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate other amines; multistep reaction;A 95%
B 85%
3-Methylbutenoic acid
541-47-9

3-Methylbutenoic acid

benzyl 2-amino-(R)-4,6-O-benzylidene-2-deoxy-β-D-allopyranoside
195006-98-5

benzyl 2-amino-(R)-4,6-O-benzylidene-2-deoxy-β-D-allopyranoside

benzyl (R)-4,6-O-benzylidene-2-deoxy-2-(3-methyl-2-butenamido)-β-D-allopyranoside
434948-91-1

benzyl (R)-4,6-O-benzylidene-2-deoxy-2-(3-methyl-2-butenamido)-β-D-allopyranoside

Conditions
ConditionsYield
With trichloroacetic acid pentachlorophenyl ester; triethylamine In tetrahydrofuran at 20℃; for 8h;95%
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