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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5411-63-2 with competitive price

Cas:5411-63-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

5411-63-2 N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5411-63-2 CAS NO.5411-63-2

Cas:5411-63-2

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

2-ButenaMide, N,N-diethyl-3-Methyl-

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

N,N-diethyl-3-methyl-2-Butenamide Application:N,N-diethyl-3-methyl-2-Butenamide

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Other

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

5411-63-2

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

N,N-diethyl-3-methyl-but-2-enamide cas 5411-63-2Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

N,N-diethyl-3-methyl-but-2-enamide cas 5411-63-2

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-ButenaMide, N,N-diethyl-3-Methyl-

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barri

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

N,N-diethyl-3-methyl-2-ButenamideAppearance:white powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport) or by sea

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

5411-63-2

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Stable supply of goods and provision of high-quality services Application:As raw materials in the field of medicine and biology

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-ButenaMide, N,N-diethyl-3-Methyl-

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

5411-63-2 CAS NO.5411-63-2

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Wising Chem Co., Ltd

Henan Wising Chem specializes in sourcing chemicals in China. We are associated with many trusted manufacturers each having different areas of expertise required for meeting the needs of our local as well as overseas buyers. We have access to custom

2-ButenaMide, N,N-diethyl-3-Methyl-

Cas:5411-63-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

N,N-diethyl-3-methyl-but-2-enamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jusheng Technology Co., Ltd.,

1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:10 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Shandong Jiashisheng Biotechnolgy Co.,Ltd

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

N,N-diethyl-3-methyl-2-Butenamide

Cas:5411-63-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

3,3-Dimethylacryloyl chloride
3350-78-5

3,3-Dimethylacryloyl chloride

diethylamine
109-89-7

diethylamine

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

Conditions
ConditionsYield
90%
With diethyl ether
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

N,N-diethyl-1,2,2-trichlorovinylamine
686-10-2

N,N-diethyl-1,2,2-trichlorovinylamine

acetone
67-64-1

acetone

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

Conditions
ConditionsYield
(i), (ii) /BRN= 635680/, (iii) (hydrolysis); Multistep reaction;
2-methylallylmagnesium chloride
5674-01-1

2-methylallylmagnesium chloride

2,2-Dimethyl-but-3-enoic acid diethylamide

2,2-Dimethyl-but-3-enoic acid diethylamide

A

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

B

N,N-diethyl-3-methyl-3-butenamide
62721-80-6

N,N-diethyl-3-methyl-3-butenamide

Conditions
ConditionsYield
In tetrahydrofuran; hexane at 20℃; for 1h; Yield given. Yields of byproduct given;
With lithium diisopropyl amide In tetrahydrofuran; hexane at 20℃; for 1h; Yield given. Yields of byproduct given;
carbon monoxide
201230-82-2

carbon monoxide

diethylamine
109-89-7

diethylamine

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

A

diethyl-methallyl-amine
19737-36-1

diethyl-methallyl-amine

B

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

C

N,N-diethyl-3-methyl-3-butenamide
62721-80-6

N,N-diethyl-3-methyl-3-butenamide

D

4-Methyl-2-oxo-pent-3-enoic acid diethylamide

4-Methyl-2-oxo-pent-3-enoic acid diethylamide

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In benzene under 76000 Torr; Ambient temperature;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

N,N-diethyl-3-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanamide

N,N-diethyl-3-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanamide

Conditions
ConditionsYield
With methanol; water; caesium carbonate; bis(1,5-cyclooctadiene)nickel (0); tricyclohexylphosphine In toluene at 20℃; for 7h;80%
triethylsilyl chloride
994-30-9

triethylsilyl chloride

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

A

(Z)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide
1174909-04-6

(Z)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide

B

(E)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide
1174909-05-7

(E)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With lithium diisopropyl amide In tetrahydrofuran at -78 - -75℃; for 1h; Inert atmosphere;
Stage #2: triethylsilyl chloride In tetrahydrofuran at -78℃; for 18.5h; Inert atmosphere; Reflux;
Stage #3: With water; ammonium chloride In tetrahydrofuran Saturated solution; optical yield given as %de; diastereoselective reaction;
A 21%
B 47%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

1-chloro-2,4-dimethoxybenzene
7051-13-0

1-chloro-2,4-dimethoxybenzene

5,7-dimethoxy-2-methyl-4-naphthol
106914-39-0

5,7-dimethoxy-2-methyl-4-naphthol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide In tetrahydrofuran -78 deg C, 1 h, rt;46%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

A

(Z)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide
1174909-02-4

(Z)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide

B

(E)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide
1174909-03-5

(E)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide

C

N,N-diethyl-3-methyl-3-butenamide
62721-80-6

N,N-diethyl-3-methyl-3-butenamide

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With lithium diisopropyl amide In tetrahydrofuran at -78 - -75℃; for 1h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78℃; for 17.5h; Inert atmosphere; Reflux;
Stage #3: With water; ammonium chloride In tetrahydrofuran Saturated solution; optical yield given as %de; diastereoselective reaction;
A 39%
B 35%
C n/a
3-methoxyphenyl bromide
2398-37-0

3-methoxyphenyl bromide

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

4-hydroxy-5-methoxy-2-methyl-naphthalene
22273-56-9

4-hydroxy-5-methoxy-2-methyl-naphthalene

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With n-butyllithium; N-cyclohexylisopropylamine In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 3-methoxyphenyl bromide In tetrahydrofuran at 20℃; for 18h; Diels-Alder reaction; Inert atmosphere;
35%
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
3,3-Dimethylacryloyl chloride
3350-78-5

3,3-Dimethylacryloyl chloride

diethylamine
109-89-7

diethylamine

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

Conditions
ConditionsYield
90%
With diethyl ether
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

N,N-diethyl-1,2,2-trichlorovinylamine
686-10-2

N,N-diethyl-1,2,2-trichlorovinylamine

acetone
67-64-1

acetone

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

Conditions
ConditionsYield
(i), (ii) /BRN= 635680/, (iii) (hydrolysis); Multistep reaction;
2-methylallylmagnesium chloride
5674-01-1

2-methylallylmagnesium chloride

2,2-Dimethyl-but-3-enoic acid diethylamide

2,2-Dimethyl-but-3-enoic acid diethylamide

A

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

B

N,N-diethyl-3-methyl-3-butenamide
62721-80-6

N,N-diethyl-3-methyl-3-butenamide

Conditions
ConditionsYield
In tetrahydrofuran; hexane at 20℃; for 1h; Yield given. Yields of byproduct given;
With lithium diisopropyl amide In tetrahydrofuran; hexane at 20℃; for 1h; Yield given. Yields of byproduct given;
carbon monoxide
201230-82-2

carbon monoxide

diethylamine
109-89-7

diethylamine

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

A

diethyl-methallyl-amine
19737-36-1

diethyl-methallyl-amine

B

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

C

N,N-diethyl-3-methyl-3-butenamide
62721-80-6

N,N-diethyl-3-methyl-3-butenamide

D

4-Methyl-2-oxo-pent-3-enoic acid diethylamide

4-Methyl-2-oxo-pent-3-enoic acid diethylamide

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In benzene under 76000 Torr; Ambient temperature;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

N,N-diethyl-3-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanamide

N,N-diethyl-3-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanamide

Conditions
ConditionsYield
With methanol; water; caesium carbonate; bis(1,5-cyclooctadiene)nickel (0); tricyclohexylphosphine In toluene at 20℃; for 7h;80%
triethylsilyl chloride
994-30-9

triethylsilyl chloride

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

A

(Z)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide
1174909-04-6

(Z)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide

B

(E)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide
1174909-05-7

(E)-N,N-diethyl-3-methyl-4-triethylsilyl-but-2-enamide

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With lithium diisopropyl amide In tetrahydrofuran at -78 - -75℃; for 1h; Inert atmosphere;
Stage #2: triethylsilyl chloride In tetrahydrofuran at -78℃; for 18.5h; Inert atmosphere; Reflux;
Stage #3: With water; ammonium chloride In tetrahydrofuran Saturated solution; optical yield given as %de; diastereoselective reaction;
A 21%
B 47%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

1-chloro-2,4-dimethoxybenzene
7051-13-0

1-chloro-2,4-dimethoxybenzene

5,7-dimethoxy-2-methyl-4-naphthol
106914-39-0

5,7-dimethoxy-2-methyl-4-naphthol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide In tetrahydrofuran -78 deg C, 1 h, rt;46%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

A

(Z)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide
1174909-02-4

(Z)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide

B

(E)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide
1174909-03-5

(E)-N,N-diethyl-3-methyl-4-trimethylsilyl-but-2-enamide

C

N,N-diethyl-3-methyl-3-butenamide
62721-80-6

N,N-diethyl-3-methyl-3-butenamide

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With lithium diisopropyl amide In tetrahydrofuran at -78 - -75℃; for 1h; Inert atmosphere;
Stage #2: chloro-trimethyl-silane In tetrahydrofuran at -78℃; for 17.5h; Inert atmosphere; Reflux;
Stage #3: With water; ammonium chloride In tetrahydrofuran Saturated solution; optical yield given as %de; diastereoselective reaction;
A 39%
B 35%
C n/a
3-methoxyphenyl bromide
2398-37-0

3-methoxyphenyl bromide

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

4-hydroxy-5-methoxy-2-methyl-naphthalene
22273-56-9

4-hydroxy-5-methoxy-2-methyl-naphthalene

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With n-butyllithium; N-cyclohexylisopropylamine In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 3-methoxyphenyl bromide In tetrahydrofuran at 20℃; for 18h; Diels-Alder reaction; Inert atmosphere;
35%
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

4-Bromoveratrole
2859-78-1

4-Bromoveratrole

5,6-dimethoxy-2-methyl-4-naphthol
106914-41-4

5,6-dimethoxy-2-methyl-4-naphthol

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With n-butyllithium; N-cyclohexylisopropylamine In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 4-Bromoveratrole In tetrahydrofuran at 20℃; for 18h; Diels-Alder reaction; Inert atmosphere;
31%
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2,4-dibromo-1-(methoxymethoxy)benzene
21571-52-8

2,4-dibromo-1-(methoxymethoxy)benzene

A

5-bromo-8-(methoxymethoxy)-3-methyl-1-naphthalenol
160538-97-6

5-bromo-8-(methoxymethoxy)-3-methyl-1-naphthalenol

B

8-bromo-5-(methoxymethoxy)-3-methyl-1-naphthalenol

8-bromo-5-(methoxymethoxy)-3-methyl-1-naphthalenol

C

N,N-diethyl-2-[2-bromo-5-(methoxymethoxy)phenyl]-3-methyl-3-butenoic acid amide

N,N-diethyl-2-[2-bromo-5-(methoxymethoxy)phenyl]-3-methyl-3-butenoic acid amide

D

N,N-diethyl-2-[5-bromo-2-(methoxymethoxy)phenyl]-3-methyl-3-butenoic acid amide

N,N-diethyl-2-[5-bromo-2-(methoxymethoxy)phenyl]-3-methyl-3-butenoic acid amide

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Metallation;
Stage #2: 2,4-dibromo-1-(methoxymethoxy)benzene With lithium cyclohexylisopropylamide In tetrahydrofuran; hexane at 0℃; for 14h; Cycloaddition; Condensation; Further byproducts given;
A 31%
B 7%
C n/a
D n/a
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

N-cyclohexylisopropylamine
1195-42-2

N-cyclohexylisopropylamine

2,4-dibromo-1-(methoxymethoxy)benzene
21571-52-8

2,4-dibromo-1-(methoxymethoxy)benzene

α-naphthol
90-15-3

α-naphthol

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran29%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2,4-dibromo-1-(methoxymethoxy)benzene
21571-52-8

2,4-dibromo-1-(methoxymethoxy)benzene

5-bromo-8-(methoxymethoxy)-3-methyl-1-naphthalenol
160538-97-6

5-bromo-8-(methoxymethoxy)-3-methyl-1-naphthalenol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide21%
With lithium cyclohexylisopropylamide In tetrahydrofuran at -78 - 0℃; for 24h;20%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

1-bromo-3,4,5-trimethoxybenzene
2675-79-8

1-bromo-3,4,5-trimethoxybenzene

5,6,7-trimethoxy-2-methyl-4-naphthol
6395-25-1

5,6,7-trimethoxy-2-methyl-4-naphthol

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With n-butyllithium; N-cyclohexylisopropylamine In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: 1-bromo-3,4,5-trimethoxybenzene In tetrahydrofuran at 20℃; for 18h; Diels-Alder reaction; Inert atmosphere;
21%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2,2'-dimethoxy-3,3',5,5'-tetrabromobiphenyl
855255-50-4

2,2'-dimethoxy-3,3',5,5'-tetrabromobiphenyl

4,4'-dibromodiospyrol

4,4'-dibromodiospyrol

Conditions
ConditionsYield
Stage #1: N,N-dimethylamino-3,3-diethylacrylamide With 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: 3,3',5,5'-tetrabromo-2,2'-dimethoxybiphenyl In tetrahydrofuran at -78 - 20℃;
20%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

Limettin
487-06-9

Limettin

1,3-Dimethoxy-9-methyl-benzo[c]chromen-6-one

1,3-Dimethoxy-9-methyl-benzo[c]chromen-6-one

Conditions
ConditionsYield
With trichlorophosphate13%
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

A

N,N-diethyl-3-methylbutanamide
533-32-4

N,N-diethyl-3-methylbutanamide

B

2-isopropyl-3,3-dimethyl-glutaric acid bis-diethylamide

2-isopropyl-3,3-dimethyl-glutaric acid bis-diethylamide

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

N,N-Diethyl-2,3-dibrom-3-methyl-buttersaeureamid
91367-35-0

N,N-Diethyl-2,3-dibrom-3-methyl-buttersaeureamid

Conditions
ConditionsYield
With bromine In tetrachloromethane
bromobenzene
108-86-1

bromobenzene

N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

3-methylnaphthalen-1-ol
13615-40-2

3-methylnaphthalen-1-ol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2-bromoanisole
578-57-4

2-bromoanisole

A

4-hydroxy-5-methoxy-2-methyl-naphthalene
22273-56-9

4-hydroxy-5-methoxy-2-methyl-naphthalene

B

N,N-diethyl-2-isopropenyl-2-(3'-methoxyphenyl)acetamide
106914-38-9

N,N-diethyl-2-isopropenyl-2-(3'-methoxyphenyl)acetamide

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide Product distribution; multistep reaction: 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, thenn room temp., overnight. Investigation of different reagents and compounds;
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction. Yields of byproduct given;
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, room temp., overnight; Yield given. Multistep reaction. Yields of byproduct given;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

9-bromophenanthrene
573-17-1

9-bromophenanthrene

3-Methyl-triphenylen-1-ol
106914-42-5

3-Methyl-triphenylen-1-ol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

1-bromo-2-(methoxymethoxy)benzene
68314-54-5

1-bromo-2-(methoxymethoxy)benzene

8-methoxymethoxy-3-methyl-1-naphthalenol
106914-40-3

8-methoxymethoxy-3-methyl-1-naphthalenol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2-chloro-1,4-dimethoxybenzene
2100-42-7

2-chloro-1,4-dimethoxybenzene

5,8-dimethoxy-3-methylnaphthalen-1-ol
50559-08-5

5,8-dimethoxy-3-methylnaphthalen-1-ol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

1-chloro-3,5-dimethoxybenzene
7051-16-3

1-chloro-3,5-dimethoxybenzene

5,7-dimethoxy-2-methyl-4-naphthol
106914-39-0

5,7-dimethoxy-2-methyl-4-naphthol

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2-chloro-5-methylanisole
73909-16-7

2-chloro-5-methylanisole

1-Hydroxy-8-methoxy-3,6-dimethyl-naphthalin
778-99-4

1-Hydroxy-8-methoxy-3,6-dimethyl-naphthalin

Conditions
ConditionsYield
With lithium cyclohexylisopropylamide 1) THF, hexane, -78 deg C, 1 h; 2) THF, -20 deg C, then room temp., overnight; Yield given. Multistep reaction;
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

2-isopropyl-3,3-dimethyl-glutaric acid

2-isopropyl-3,3-dimethyl-glutaric acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium alanate; diethyl ether
2: aqueous hydrochloric acid
View Scheme
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

N,N-Diethyl-2,3-di-S-acetyl-3-methyl-buttersaeureamid
92158-68-4

N,N-Diethyl-2,3-di-S-acetyl-3-methyl-buttersaeureamid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Br2 / CCl4
2: Py / benzene
View Scheme
N,N-dimethylamino-3,3-diethylacrylamide
5411-63-2

N,N-dimethylamino-3,3-diethylacrylamide

C9H16NO(1-)

C9H16NO(1-)

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran at -78 - -20℃; for 1.25h; Inert atmosphere;

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