DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:5509-65-9
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryName 2,6-Difluoroaniline Synonyms 2,6-Difluorobenzenamine Molecular Structure Molecular Formula
high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:5509-65-9
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryCHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis
Cas:5509-65-9
Min.Order:1 Kilogram
FOB Price: $2.0 / 3.0
Type:Trading Company
inquiry2,6-Difluoroaniline Basic information Product Name: 2,6-Difluoroaniline Synonyms: Benzenamine, 2,6-difluoro-;2,6-DIFLUOROANILINE;2,6-DIFLUOROBENZENAMINE;2,6-DIFLUOROANILINE, 97+%;2,6-Dif
Cas:5509-65-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:5509-65-9
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryProduct Name 2,6-Difluoroaniline Identification Synonyms 2,6-Difluorobenzenamine Molecular Formula C6H5F2N Molecular Weight 129.11 CAS Number 5509-65-9 EINECS/ELINCS 226-853-0 Appearance: Clear yellow liquid Storage:Preserve in well-closed, light-re
Cas:5509-65-9
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his products from many recent effective packing ways;
1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white or off-white powder Storage:Store in sealed containers
Cas:5509-65-9
Min.Order:100 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:5509-65-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:5509-65-9
Min.Order:1 Gram
FOB Price: $6.0 / 9.0
Type:Trading Company
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:5509-65-9
Min.Order:1 Kilogram
FOB Price: $48.2 / 51.6
Type:Trading Company
inquiry2,6-DifluoroanilineCAS:5509-65-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme
Cas:5509-65-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:5509-65-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct Detail Minimum Order Qty. 10 Gram
Cas:5509-65-9
Min.Order:20 Metric Ton
Negotiable
Type:Trading Company
inquiry2,6-Difluoroaniline CAS:5509-65-9 Specification Item Standard Test Results Identification A.H-NMR:Comply with the structure Complies B.LC-MS:Comply with t
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:5509-65-9
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:5509-65-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:5509-65-9
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryMassive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Cas:5509-65-9
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:5509-65-9
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct name: 2,6-Difluoroaniline CAS No.:5509-65-9 Molecule Formula:C6H5F2N Molecule Weight:129.11 Purity: 99.0% Package: 200kg/drum Description:Light yellow to brown liquid Manufacture Standards:Enterprise Standard
Cas:5509-65-9
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:5509-65-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry2,6-difluorobenzamide
2,6-difluoroaniline
Conditions | Yield |
---|---|
With sodium hypochlorite; sodium hydroxide In water at -5℃; for 2h; Reagent/catalyst; Hofmann Rearrangement; Large scale; Green chemistry; | 92% |
With sodium hypochlorite; sodium hydroxide at -5℃; for 1.5h; Large scale; | 89.6% |
1-chloro-2,6-difluorobenzene
A
ortho-difluorobenzene
B
2,6-difluoroaniline
Conditions | Yield |
---|---|
With ammonium hydroxide; copper(I) oxide at 160℃; for 24h; bomb; Further byproducts given; | A 2% B 71% |
Conditions | Yield |
---|---|
With naphtophenone at 25℃; for 4h; Product distribution; Irradiation; further tenmperatures; | A 54% B 13% C 10% |
Conditions | Yield |
---|---|
With sodium azide; sulfuric acid |
1-chloro-3,5-difluorobenzene
A
2,4-difluorophenylamine
B
2,6-difluoroaniline
Conditions | Yield |
---|---|
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; |
Conditions | Yield |
---|---|
With ammonium hydroxide; cesium fluoride; copper(I) oxide 1.) N,N'-dimethylethyleneurea, 250 deg C (bomb), 12 h, 2.) 170 deg C (bomb), 24 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given; | |
With ammonium hydroxide; cesium fluoride; copper(I) oxide 1.) N,N'-dimethylethyleneurea, 250 deg C (bomb), 12 h, 2.) 160 deg C (bomb), 24 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) CsF, 2.) H2, N-ethyldiethanolamine / 2.) 10percent Pd/C / 1.) N,N'-dimethylethyleneurea, 250 deg C (bomb), 12 h, 2.) ethylene glycol, 100 deg C, 200 psi 2: 71 percent / conc. NH4OH / Cu2O / 24 h / 160 °C / bomb View Scheme | |
Multi-step reaction with 2 steps 1: CsF / various solvent(s) / 12 h / 250 °C / reaction carried out in a bomb 2: 71 percent / conc. NH4OH / Cu2O / 24 h / 160 °C / bomb View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: KF / various solvent(s) / 12 h / 300 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: (i) nBuLi, (ii) /BRN= 1900390/ 2: NaN3, H2SO4 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: copper(I) bromide; pyridine / toluene / 20 h / 60 °C 2.1: potassium nitrate; bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethyl acetate / 12 h / 90 °C / Sealed tube 2.2: 0.17 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: copper(I) bromide; pyridine / toluene / 20 h / 60 °C 2.1: potassium nitrate; bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethanol / 12 h / 55 °C / Sealed tube 2.2: 0.17 h / 20 °C 3.1: copper(I) bromide; pyridine / toluene / 20 h / 60 °C 4.1: potassium nitrate; bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethyl acetate / 12 h / 90 °C / Sealed tube 4.2: 0.17 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Stage #1: 2,2'-difluoroazobenzene With N-fluorobis(benzenesulfon)imide; potassium nitrate; bis(dibenzylideneacetone)-palladium(0) In ethyl acetate at 90℃; for 12h; Sealed tube; Stage #2: With sodium tetrahydroborate; copper(l) chloride In ethanol at 20℃; for 0.166667h; | 41.3 mg |
Multi-step reaction with 2 steps 1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 105 °C / Sealed tube 2: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme |
Azobenzene
2,6-difluoroaniline
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: potassium nitrate; bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethanol / 12 h / 55 °C / Sealed tube 1.2: 0.17 h / 20 °C 2.1: copper(I) bromide; pyridine / toluene / 20 h / 60 °C 3.1: potassium nitrate; bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethyl acetate / 12 h / 90 °C / Sealed tube 3.2: 0.17 h / 20 °C View Scheme | |
Multi-step reaction with 3 steps 1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 55 °C 2: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 105 °C / Sealed tube 3: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme |
2,6-difluoroaniline
Conditions | Yield |
---|---|
With sodium tetrahydroborate; copper(l) chloride In ethanol at 20℃; | 23.2 mg |
2,6-difluoroaniline
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: ethyl acetate / 2 h / 20 °C / Sealed tube 2: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 55 °C 3: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 105 °C / Sealed tube 4: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme | |
Multi-step reaction with 4 steps 1: N-fluorobis(benzenesulfon)imide / ethyl acetate / 2 h / 20 °C / Sealed tube 2: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 55 °C 3: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 105 °C / Sealed tube 4: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme | |
Multi-step reaction with 5 steps 1: dichloromethane / 24 h / 20 °C 2: ethyl acetate / 2 h / 20 °C / Sealed tube 3: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 55 °C 4: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 105 °C / Sealed tube 5: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme |
2,6-difluoroaniline
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: ethyl acetate / 2 h / 20 °C / Sealed tube 2: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 55 °C 3: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 105 °C / Sealed tube 4: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme |
1-(2,4,6-trimethylphenyl)-2-phenyldiazene
2,6-difluoroaniline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 100 °C / Sealed tube 2: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C View Scheme |
2,6-difluoroaniline
Conditions | Yield |
---|---|
With sodium tetrahydroborate; copper(l) chloride In ethanol at 20℃; | 24.8 mg |
2,6-difluoroaniline
1,3-difluoro-2-nitrosobenzene
Conditions | Yield |
---|---|
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 23℃; Inert atmosphere; | 100% |
With Oxone In dichloromethane; water at 20℃; for 15h; | 99% |
With potassium peroxymonosulfate sulfate In dichloromethane; water at 20℃; for 24h; | 86.49% |
2,6-difluoroaniline
2,6-difluoro-4-iodoaniline
Conditions | Yield |
---|---|
With N-iodo-succinimide; toluene-4-sulfonic acid In N,N-dimethyl-formamide at 5 - 20℃; for 2.5h; | 100% |
With Iodine monochloride In acetic acid at 20℃; for 0.25h; | 95% |
Stage #1: 2,6-difluoroaniline With Iodine monochloride; acetic acid In water at 20℃; for 0.25h; Stage #2: With sodium carbonate In water | 95% |
2,6-difluoroaniline
Ethyl oxalyl chloride
ethyl 2-((2,6-difluorophenyl)amino)-2-oxoacetate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 0 - 20℃; for 24h; | 100% |
With triethylamine In tetrahydrofuran at 0℃; for 16h; Inert atmosphere; |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; | 99% |
With hydrogenchloride In dichloromethane for 3h; Ambient temperature; | 78% |
In hydrogenchloride; dichloromethane |
2,6-difluoroaniline
4-bromo-2,6-difluoroaniline
Conditions | Yield |
---|---|
With N-Bromosuccinimide In acetonitrile at 20℃; | 99% |
With N-Bromosuccinimide In chloroform at 20℃; | 93% |
Stage #1: 2,6-difluoroaniline With bromine; acetic acid In water at 20℃; for 0.25h; Stage #2: With sodium carbonate In water | 92% |
Conditions | Yield |
---|---|
In dichloromethane at 20℃; for 16h; | 98% |
In toluene at 0 - 20℃; for 4h; Solvent; Temperature; | 94% |
91% |
Conditions | Yield |
---|---|
With trifluoroacetic acid In toluene at 120℃; for 16h; | 98% |
2,6-difluoroaniline
potassium ethyl xanthogenate
2-mercapto-4-fluorobenzothiazole
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 120℃; for 0.133333h; microwave irradiation; | 98% |
In N,N-dimethyl-formamide at 120℃; for 3.5h; Inert atmosphere; | 98% |
In N,N-dimethyl-formamide at 120℃; for 3.5h; Inert atmosphere; | 98% |
In 1-methyl-pyrrolidin-2-one at 90℃; for 2h; | 56% |
In N,N-dimethyl-formamide at 120℃; for 4h; |
methyl 3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}-2-methylphenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzoate
2,6-difluoroaniline
N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}-2-methylphenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Conditions | Yield |
---|---|
Stage #1: methyl 3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}-2-methylphenyl)amino}-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl)benzoate; 2,6-difluoroaniline With sodium hexamethyldisilazane In tetrahydrofuran at 20℃; for 0.0833333h; Stage #2: With sodium hydrogencarbonate In tetrahydrofuran; water | 98% |
Conditions | Yield |
---|---|
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tri-tert-butyl phosphine; sodium t-butanolate In toluene at 100℃; Buchwald-Hartwig Coupling; Inert atmosphere; | 98% |
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tri-tert-butyl phosphine; sodium t-butanolate In toluene at 100℃; for 16h; Buchwald-Hartwig Coupling; Inert atmosphere; | 96% |
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tri-tert-butyl phosphine In toluene at 100℃; Inert atmosphere; |
Conditions | Yield |
---|---|
Stage #1: 2,6-difluoroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h; Stage #2: acetylacetone With sodium acetate In methanol; water at 20℃; | 98% |
Stage #1: 2,6-difluoroaniline With hydrogenchloride; acetic acid; sodium nitrite In water at 0℃; for 0.75h; Stage #2: acetylacetone With sodium acetate In ethanol; water for 1h; | 94% |
Conditions | Yield |
---|---|
Stage #1: 2,6-difluoroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h; Stage #2: acetylacetone With sodium acetate In ethanol; water at 0 - 20℃; for 10h; | 98% |
2,6-difluoroaniline
2-nitrobenzyl chloride
N-(2,6-difluorophenyl)-2-nitrobenzamide
Conditions | Yield |
---|---|
In 1,4-dioxane at 20℃; | 97% |
Conditions | Yield |
---|---|
In [D3]acetonitrile at 20℃; for 6h; Inert atmosphere; | 97% |
Conditions | Yield |
---|---|
Stage #1: acetaldehyde With sodium tetrahydroborate; acetic acid In 1,2-dichloro-ethane at 0 - 20℃; for 1h; Stage #2: 2,6-difluoroaniline In 1,2-dichloro-ethane at 20℃; | 97% |
Conditions | Yield |
---|---|
Stage #1: 2-bromothiazole-4-carboxylic Acid With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 0.25h; Stage #2: 2,6-difluoroaniline In N,N-dimethyl-formamide at 20℃; for 16h; | 96% |
2,6-difluoroaniline
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; Inert atmosphere; | 96% |
With triethylamine In dichloromethane at 20℃; for 1h; | 96% |
2,6-difluoroaniline
2-(4-bromophenyl)benzothiazole
Conditions | Yield |
---|---|
With C47H70BrO4PPdSi; sodium t-butanolate In tetrahydrofuran at 20℃; for 1h; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere; Sealed tube; | 96% |
2,6-difluoroaniline
2-(bromomethyl)benzonitrile
Conditions | Yield |
---|---|
at 150℃; for 16h; Schlenk technique; Inert atmosphere; | 95.3% |
2,6-difluoroaniline
pivaloyl chloride
N-(2,6-difluorophenyl)trimethylacetamide
Conditions | Yield |
---|---|
With triethylamine In toluene at 0 - 50℃; | 95% |
In toluene at 20℃; Reflux; |
2-chlorosulfonyl-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine
2,6-difluoroaniline
florasulam
Conditions | Yield |
---|---|
Stage #1: 2,6-difluoroaniline With N-chloro-succinimide; dimethylsulfide In acetonitrile at -20℃; Inert atmosphere; Stage #2: 2-chlorosulfonyl-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine With 3-Methylpyridine In acetonitrile at 20 - 40℃; Temperature; Inert atmosphere; | 94.2% |
In propylene glycol at 40℃; for 1.5h; Product distribution / selectivity; | 88% |
In propylene glycol; dichloromethane at 25 - 45℃; for 5.5 - 8h; Product distribution / selectivity; | 84.6% |
2,6-difluoroaniline
N-sulfinyl-2,6-diflouroaniline
Conditions | Yield |
---|---|
With N-(chlorosulfinyl)imidazole In dichloromethane at -40 - 20℃; for 1.5h; Inert atmosphere; | 94% |
With thionyl chloride |
Conditions | Yield |
---|---|
With potassium hexamethylsilazane In tetrahydrofuran at 100℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube; Green chemistry; | 94% |
2,6-difluoroaniline
4-acetophenyl triflate
Conditions | Yield |
---|---|
With C46H27F24FeNiP2(1+)*CF3O3S(1-); triethylamine In 2-methyltetrahydrofuran at 100℃; for 16h; Concentration; Schlenk technique; Inert atmosphere; Glovebox; Sealed tube; | 94% |
Conditions | Yield |
---|---|
With acetic acid; isopentyl nitrite at 0 - 5℃; Diazotization; | 93% |
2,6-difluoroaniline
ortho-nitrofluorobenzene
2,6-difluoro-N-(2-nitrophenyl)aniline
Conditions | Yield |
---|---|
Stage #1: 2,6-difluoroaniline With sodium tert-amylate In tetrahydrofuran at 0 - 10℃; for 1.11667h; Large scale reaction; Stage #2: ortho-nitrofluorobenzene In tetrahydrofuran at 9 - 15℃; for 3h; Thermodynamic data; Concentration; Time; Large scale reaction; | 93% |
Stage #1: 2,6-difluoroaniline With tert.-butyl lithium In tetrahydrofuran; pentane at -78℃; for 0.166667h; Stage #2: ortho-nitrofluorobenzene In tetrahydrofuran; pentane at 0 - 20℃; for 0.5h; | 68% |
Stage #1: 2,6-difluoroaniline With sodium hydride In N,N-dimethyl-formamide for 0.5h; Stage #2: ortho-nitrofluorobenzene In N,N-dimethyl-formamide for 16h; |
2-chloro-7-(1-methyl-1H-pyrazol-4-yl)-1,5-naphthyridine
2,6-difluoroaniline
C18H13F2N5
Conditions | Yield |
---|---|
Stage #1: 2,6-difluoroaniline With lithium hexamethyldisilazane In tetrahydrofuran at 0℃; for 1h; Stage #2: 2-chloro-7-(1-methyl-1H-pyrazol-4-yl)-1,5-naphthyridine In tetrahydrofuran at 0 - 20℃; | 93% |
1,3-diphenyl-3-hydroxypropene
2,6-difluoroaniline
Conditions | Yield |
---|---|
With copper(II) bis(trifluoromethanesulfonate) In 1,2-dichloro-ethane at 70℃; for 3h; regioselective reaction; | 93% |
2,6-difluoroaniline
4-bromo-2,6-difluoroaniline
Conditions | Yield |
---|---|
Stage #1: 2,6-difluoroaniline; 4-bromo-2,6-difluoroaniline With Oxone In dichloromethane; water at 20℃; for 17h; Inert atmosphere; Stage #2: In acetic acid; toluene; trifluoroacetic acid at 20℃; | 93% |
Conditions | Yield |
---|---|
In toluene at 0 - 20℃; for 4h; | 93% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View